Accéder directement au contenu

Francois Chevalier

François Chevalier
144
Documents
Affiliations actuelles
  • 1061150
  • 53953
  • 56527
  • 20287
Identifiants chercheurs
Contact

Présentation

Dr. François Chevalier, PhD, HDR, with a background in protein chemistry and molecular biology, received his doctoral degree in biochemistry in 2001 (INRA, Nantes, France), for the biochemical characterization of glycated proteins. He did a 5 years post-doctoral research positions in Montpellier (INRA, France) with a special focus on global analysis of proteins using two-dimensional electrophoresis and mass spectrometry. Following a research positions in Cork (UCC, Ireland) with a study of protein quality using proteomics tools, he is currently employed in CEA (DRF-IRAMIS-CIMAP in Caen) as team leader in radiation biology in the ARIA group (Applications in Radiobiology with Accelerated Ions). Dr. François Chevalier is specialized in radiation-biology of radioresistant cancer models and bystander effects in a context of hadrontherapy. He has published more than 70 scientific and technical papers in peer reviewed journals.

Domaines de recherche

Cancer Biologie cellulaire Génomique, Transcriptomique et Protéomique [q-bio.GN] Biochimie, Biologie Moléculaire

Publications

Image document

NF-κB in the Radiation Response of A549 Non-Small Cell Lung Cancer Cells to X-rays and Carbon Ions under Hypoxia

Hasan Nisar , Paulina Sanchidrián González , Frederik Labonté , Claudia Schmitz , Marie Roggan
International Journal of Molecular Sciences, 2024, 25 (8), pp.4495. ⟨10.3390/ijms25084495⟩
Article dans une revue hal-04553905v1
Image document

Hypoxia Modulates Radiosensitivity and Response to Different Radiation Qualities in A549 Non-Small Cell Lung Cancer (NSCLC) Cells

Hasan Nisar , Frederik M Labonté , Marie Denise Roggan , Claudia Schmitz , François Chevalier
International Journal of Molecular Sciences, 2024, 25 (2), pp.1010. ⟨10.3390/ijms25021010⟩
Article dans une revue hal-04409075v1
Image document

In vitro hyperspectral biomarkers of human chondrosarcoma cells in nanoparticle-mediated radiosensitization using carbon ions

Mihaela Tudor , Roxana Cristina Popescu , Raluca D Negoita , Antoine Gilbert , Mihaela A Ilisanu
Scientific Reports, 2023, 13 (1), pp.14878. ⟨10.1038/s41598-023-41991-9⟩
Article dans une revue hal-04202858v1

Radiation‐Induced Transfer of Charge, Atoms and Energy within Isolated Biomolecular Systems

François Chevalier , Thomas Schlathölter , Jean-Christophe Poully
ChemBioChem, 2023, ⟨10.1002/cbic.202300543⟩
Article dans une revue hal-04216855v1
Image document

A Longitudinal Study of Individual Radiation Responses in Pediatric Patients Treated with Proton and Photon Radiotherapy, and Interventional Cardiology: Rationale and Research Protocol of the HARMONIC Project

Maria Grazia Andreassi , Nadia Haddy , Mats Harms-Ringdahl , Jonica Campolo , Andrea Borghini
International Journal of Molecular Sciences, 2023, 24 (9), pp.8416. ⟨10.3390/ijms24098416⟩
Article dans une revue hal-04103396v1
Image document

Chondrosarcoma Resistance to Radiation Therapy: Origins and Potential Therapeutic Solutions

Antoine Gilbert , Mihaela Tudor , Juliette Montanari , Kevin Commenchail , Diana Iulia Savu
Cancers, 2023, 15 (7), pp.1962. ⟨10.3390/cancers15071962⟩
Article dans une revue hal-04058836v1

CYCLHAD: A French Facility Dedicated for Research and Treatment in Hadrontherapy

François Chevalier , P. Lesueur , G. Gaubert
Nuclear Physics News, 2022, 32 (2), pp.27-31. ⟨10.1080/10619127.2022.2063002⟩
Article dans une revue hal-03759681v1
Image document

Radioresistance of Non-Small Cell Lung Cancers and Therapeutic Perspectives

Mathieu Césaire , Juliette Montanari , Hubert Curcio , Delphine Lerouge , Radj Gervais
Cancers, 2022, 14 (12), pp.2829. ⟨10.3390/cancers14122829⟩
Article dans une revue hal-03697588v1
Image document

Label-Free Direct Mass Spectrometry Analysis of the Bystander Effects Induced in Chondrocytes by Chondrosarcoma Cells Irradiated with X-rays and Carbon Ions

Antoine Gilbert , Valentin Payet , Benoît Bernay , Elisabeth Chartier-Garcia , Isabelle Testard
Frontiers in Bioscience-Landmark, 2022, 27 (9), pp.277. ⟨10.31083/j.fbl2709277⟩
Article dans une revue hal-03814877v1

Avoidance or adaptation of radiotherapy in patients with cancer with Li-Fraumeni and heritable TP53-related cancer syndromes

Juliette Thariat , François Chevalier , Daniel Orbach , Luc Ollivier , Pierre-Yves Marcy
Lancet Oncology, 2021, 22 (12), pp.e562-e574. ⟨10.1016/S1470-2045(21)00425-3⟩
Article dans une revue hal-03464420v1
Image document

A Proteomic Study Suggests Stress Granules as New Potential Actors in Radiation-Induced Bystander Effects

Mihaela Tudor , Antoine Gilbert , Charlotte Lepleux , Mihaela Temelie , Sonia Hem
International Journal of Molecular Sciences, 2021, 22 (15), pp.7957. ⟨10.3390/ijms22157957⟩
Article dans une revue hal-03301338v1
Image document

Counteracting Radio-Resistance Using the Optimization of Radiotherapy

François Chevalier
International Journal of Molecular Sciences, 2020, 21 (5), pp.1767. ⟨10.3390/ijms21051767⟩
Article dans une revue hal-02503021v1

A multimodal treatment of carbon ions irradiation, miRNA-34 and mTOR inhibitor specifically control high-grade chondrosarcoma cancer stem cells

Guillaume Vares , Vidhula Ahire , Shigeaki Sunada , Eun Ho Kim , Sei Sai
Radiotherapy & Oncology, 2020, 150, pp.253-261. ⟨10.1016/j.radonc.2020.07.034⟩
Article dans une revue hal-03298410v1
Image document

Hadrontherapy Interactions in Molecular and Cellular Biology

Juliette Thariat , Samuel Valable , Carine Laurent , Siamak Haghdoost , Elodie A. Pérès
International Journal of Molecular Sciences, 2020, 21 (1), pp.133. ⟨10.3390/ijms21010133⟩
Article dans une revue hal-02429129v1
Image document

Sensitization of chondrosarcoma cells with PARP inhibitor and high-LET radiation

Mathieu Césaire , Utpal Ghosh , Jean-Baptiste Austry , Etienne Müller , Francesco Paolo Cammarata
Journal of Bone Oncology, 2019, 17, pp.100246. ⟨10.1016/j.jbo.2019.100246⟩
Article dans une revue hal-02332712v1
Image document

Bystander effectors of chondrosarcoma cells irradiated at different LET impair proliferation of chondrocytes

Charlotte Lepleux , Aurélie Marie-Brasset , Mihaela Temelie , Marion Boulanger , Émilie Brotin
Journal of Cell Communication and Signaling, 2019, 13 (3), pp.343-356. ⟨10.1007/s12079-019-00515-9⟩
Article dans une revue inserm-02125509v1
Image document

High LET Radiation Overcomes In Vitro Resistance to X-Rays of Chondrosarcoma Cell Lines

François Chevalier , Dounia Houria Hamdi , Charlotte Lepleux , Mihaela Temelie , Anaïs Nicol
Technology in Cancer Research and Treatment, 2019, 18, pp.153303381987130. ⟨10.1177/1533033819871309⟩
Article dans une revue hal-02333914v1
Image document

Combining PARP inhibition, radiation, and immunotherapy: A possible strategy to improve the treatment of cancer?

Mathieu Césaire , Juliette Thariat , Serge M. Candéias , Dinu Stefan , Yannick Saintigny
International Journal of Molecular Sciences, 2018, 19 (12), pp.3793. ⟨10.3390/ijms19123793⟩
Article dans une revue hal-01948336v1
Image document

Radiosensitization Effect of Talazoparib, a Parp Inhibitor, on Glioblastoma Stem Cells Exposed to Low and High Linear Energy Transfer Radiation

Paul Lesueur , François Chevalier , Elias A. El-Habr , Marie-Pierre Junier , Hervé Chneiweiss
Scientific Reports, 2018, 8, pp.3664. ⟨10.1038/s41598-018-22022-4⟩
Article dans une revue hal-01738585v1
Image document

Poly-(ADP-ribose)-polymerase inhibitors as radiosensitizers: a systematic review of pre-clinical and clinical human studies

Paul Lesueur , François Chevalier , Jean-Baptiste Austry , Waisse Waissi , Hélène Burckel
Oncotarget, 2017, 8 (40), ⟨10.18632/oncotarget.19079⟩
Article dans une revue hal-02493848v1
Image document

Translational research in radiobiology in the framework of France HADRON national collaboration

Claire Rodriguez-Lafrasse , Yannick Saintigny , François Chevalier , Myriam Bernaudin , Carine Laurent
Translational Cancer Research, 2017, 6 (S5), pp.S795-S806. ⟨10.21037/tcr.2017.06.33⟩
Article dans une revue hal-01610093v1

Review of the Mechanisms Involved in the Abscopal Effect and Future Directions with a Focus on Thymic Carcinoma

Paul Lesueur , François Chevalier , Dinu Stefan , Jean-Louis Habrand , Delphine Lerouge
Tumori, 2017, 103 (3), pp.217-222. ⟨10.5301/tj.5000616⟩
Article dans une revue hal-02503009v1
Image document

Poly-(ADP-ribose)-polymerase inhibitors as radiosensitizers: a systematic review of pre-clinical and clinical human studies

Paul Lesueur , François Chevalier , Jean-Baptiste Austry , Waisse Waissi , Hélène Burckel
Oncotarget, 2017, 8 (40), pp.69105-69124. ⟨10.18632/oncotarget.19079]⟩
Article dans une revue cea-01938036v1
Image document

Comparable Senescence Induction in Three-dimensional Human Cartilage Model by Exposure to Therapeutic Doses of X-rays or C-ions

Dounia Hamdi , François Chevalier , Jean-Emmanuel Groetz , Florent Durantel , Jean-Yves Thuret
International Journal of Radiation Oncology, Biology, Physics, 2016, 95 (1), pp.139 - 146. ⟨10.1016/j.ijrobp.2016.02.014⟩
Article dans une revue cea-01938049v1
Image document

A threshold of endogenous stress is required to engage cellular response to protect against mutagenesis.

Yannick Saintigny , François Chevalier , Anne Bravard , Elodie Dardillac , David Laurent
Scientific Reports, 2016, 6, pp.29412. ⟨10.1038/srep29412⟩
Article dans une revue hal-01594490v1
Image document

Dosimetry for radiobiology experiments at GANIL

Florent Durantel , Emmanuel Balanzat , Amine Cassimi , François Chevalier , Yvette Ngono-Ravache
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2016, 816, pp.70 - 77. ⟨10.1016/j.nima.2016.01.052⟩
Article dans une revue cea-01938057v1
Image document

In vitro engineering of human 3D chondrosarcoma: a preclinical model relevant for investigations of radiation quality impact

Dounia Hamdi , Sofia Barbieri , François Chevalier , Jean-Emmanuel Groetz , Florence Legendre
Article dans une revue hal-01315021v1

Impact of Therapeutic Irradiation on Healthy Articular Cartilage

Yannick Saintigny , Séverine Cruet-Hennequart , Dounia Houria Hamdi , François Chevalier , Jean-Louis Lefaix
Radiation Research, 2015, 183 (2), pp.135-146. ⟨10.1667/rr13928.1⟩
Article dans une revue hal-02493854v1

Proteomic overview and perspectives of the radiation-induced bystander effects

François Chevalier , Dounia Houria Hamdi , Yannick Saintigny , Jean-Louis Lefaix
Mutation Research/Reviews in Mutation Research, 2015, 763, pp.280-293. ⟨10.1016/j.mrrev.2014.11.008⟩
Article dans une revue hal-02503001v1

Proteomic Comparison of Equine and Bovine Milks on Renneting

Therese Uniacke-Lowe , Francois Chevalier , Sonia Hem , Patrick F. Fox , Daniel M. Mulvihill
Journal of Agricultural and Food Chemistry, 2013, 61 (11), pp.2839 - 2850. ⟨10.1021/jf3045846⟩
Article dans une revue hal-01837537v1

Proteomic Comparison of Equine and Bovine Milks on Renneting

Therese Uniacke-Lowe , François Chevalier , Sonia Hem , Patrick Fox , Daniel Mulvihill
Journal of Agricultural and Food Chemistry, 2013, 61 (11), pp.2839-2850. ⟨10.1021/jf3045846⟩
Article dans une revue hal-02493849v1
Image document

Technical updates to basic proteins focalization using IPG strips

Jordane Dépagne , François Chevalier
Proteome Science, 2012, 10 (1), pp.54. ⟨10.1186/1477-5956-10-54⟩
Article dans une revue hal-02502828v1

Impairing the microRNA biogenesis pathway induces proteome modifications characterized by size bias and enrichment in antioxidant proteins

Delphine Peric , Jean Labarre , François Chevalier , Germain Rousselet
Proteomics, 2012, 12 (14), pp.2295-2302. ⟨10.1002/pmic.201100461⟩
Article dans une revue hal-02502836v1

Accumulation of cyclophilin A isoforms in conditioned medium of irradiated breast cancer cells

François Chevalier , Jordane Dépagne , Sonia Hem , Sylvie Chevillard , Julie Bensimon
Proteomics, 2012, 12 (11), pp.1756-1766. ⟨10.1002/pmic.201100319⟩
Article dans une revue hal-02502815v1

Effect of high-pressure treatment of milk for cheese manufacture on proteolysis, lipolysis, texture and functionality of Cheddar cheese during ripening

Daniela Voigt , François Chevalier , John Donaghy , Margaret Patterson , Michael Qian
Innovative Food Science & Emerging Technologies / Innovative Food Science and Emerging Technologies , 2012, 13, pp.23-30. ⟨10.1016/j.ifset.2011.10.004⟩
Article dans une revue hal-02502753v1

Bcl-2 Inhibits Nuclear Homologous Recombination by Localizing BRCA1 to the Endomembranes

C. Laulier , A. Barascu , J. Guirouilh-Barbat , G. Pennarun , C. Le Chalony
Cancer Research, 2011, 71 (10), pp.3590-3602. ⟨10.1158/0008-5472.CAN-10-3119⟩
Article dans une revue hal-02502797v1

Proteomic analysis of Arabidopsis thaliana ecotypes with contrasted root architecture in response to phosphate deficiency

François Chevalier , Michel Rossignol
Journal of Plant Physiology, 2011, 168 (16), pp.1885-1890. ⟨10.1016/j.jplph.2011.05.024⟩
Article dans une revue hal-02501132v1

Effect of high-pressure treatment on microbiology, proteolysis, lipolysis and levels of flavour compounds in mature blue-veined cheese

Daniela Voigt , François Chevalier , Michael Qian , Alan Kelly
Innovative Food Science & Emerging Technologies / Innovative Food Science and Emerging Technologies , 2010, 11 (1), pp.68-77. ⟨10.1016/j.ifset.2009.10.009⟩
Article dans une revue hal-02502718v1

Proteins and proteolysis in pre-term and term human milk and possible implications for infant formulae

Emanuele Armaforte , Erika Curran , Thom Huppertz , C. Anthony Ryan , Maria Caboni
International Dairy Journal, 2010, 20 (10), pp.715-723. ⟨10.1016/j.idairyj.2010.03.008⟩
Article dans une revue hal-02502695v1
Image document

Highlights on the capacities of "Gel-based" proteomics

François Chevalier
Proteome Science, 2010, 8 (1), pp.23. ⟨10.1186/1477-5956-8-23⟩
Article dans une revue hal-02502775v1

Standard Dyes for Total Protein Staining in Gel-Based Proteomic Analysis

François Chevalier
Materials, 2010, 3 (10), pp.4784-4792. ⟨10.3390/ma3104784⟩
Article dans une revue hal-02502783v1

Proteomic Quantification of Disulfide-Linked Polymers in Raw and Heated Bovine Milk

François Chevalier , Alan Kelly
Journal of Agricultural and Food Chemistry, 2010, 58 (12), pp.7437-7444. ⟨10.1021/jf1010879⟩
Article dans une revue hal-02502703v1

Use of Reducing/Nonreducing Two-Dimensional Electrophoresis for the Study of Disulfide-Mediated Interactions between Proteins in Raw and Heated Bovine Milk

François Chevalier , Christophe Hirtz , Nicolas Sommerer , Alan Kelly
Journal of Agricultural and Food Chemistry, 2009, 57 (13), pp.5948-5955. ⟨10.1021/jf900518n⟩
Article dans une revue hal-02502915v1

Use of Reducing/Nonreducing Two-Dimensional Electrophoresis for the Study of Disulfide-Mediated Interactions between Proteins in Raw and Heated Bovine Milk

François Chevalier , Christophe Hirtz , Nicolas Sommerer , Alan Kelly
Journal of Agricultural and Food Chemistry, 2009, 57 (13), pp.5948-5955. ⟨10.1021/jf900518n⟩
Article dans une revue hal-02502451v1

Effect of high-pressure homogenisation on rheological properties of rennet-induced skim milk and standardised milk gels

Kristina Lodaite , François Chevalier , Emanuele Armaforte , Alan Kelly
Journal of Dairy Research, 2009, 76 (3), pp.294-300. ⟨10.1017/S0022029909004117⟩
Article dans une revue hal-02502466v1
Image document

Proteomic Studies of Saliva: A Proposal for a Standardized Handling of Clinical Samples

François Chevalier , Christophe Hirtz , Sandrine Chay , Frédéric Cuisinier , Nicolas Sommerer
Clinical Proteomics, 2007, 3 (1-4), pp.13 - 21. ⟨10.1007/s12014-007-9000-x⟩
Article dans une revue hal-01743573v1

Different Impact of Staining Procedures Using Visible Stains and Fluorescent Dyes for Large-Scale Investigation of Proteomes by MALDI-TOF Mass Spectrometry

François Chevalier , Delphine D. Centeno , Valerie Rofidal , Marc Tauzin , Olivier Martin
Journal of Proteome Research, 2006, 5 (3), pp.512-520. ⟨10.1021/pr050194n⟩
Article dans une revue hal-02501122v1

Salivary protein profiling in type I diabetes using two-dimensional electrophoresis and mass spectrometry

Christophe Hirtz , François Chevalier , Nicolas Sommerer , Isabelle Raingeard , Jacques Bringer
Clinical Proteomics, 2006, 2 (1-2), pp.117-127. ⟨10.1385/CP:2:1:117⟩
Article dans une revue hal-02502403v1

MS characterization of multiple forms of alpha-amylase in human saliva

Christophe Hirtz , François Chevalier , Delphine D. Centeno , Valerie Rofidal , Jean-Christophe Egea
Proteomics, 2005, 5 (17), pp.4597-4607. ⟨10.1002/pmic.200401316⟩
Article dans une revue hal-02501106v1

Proteomic investigation of natural variation between Arabidopsis ecotypes

François Chevalier , Olivier Martin , Valerie Rofidal , Anne-Dominique Devauchelle , Samuel Barteau
Proteomics, 2004, 4 (5), pp.1372-1381. ⟨10.1002/pmic.200300750⟩
Article dans une revue hal-02501082v1

Proteomic capacity of recent fluorescent dyes for protein staining

François Chevalier , Valerie Rofidal , Pavlina Vanova , Alexis Bergoin , Michel Rossignol
Phytochemistry, 2004, 65 (11), pp.1499-1506. ⟨10.1016/j.phytochem.2004.04.019⟩
Article dans une revue hal-02501090v1

Effects of phosphate availability on the root system architecture: large-scale analysis of the natural variation between Arabidopsis accessions

François Chevalier , M. Pata , Philippe Nacry , Patrick Doumas , M. Rossignol
Plant, Cell and Environment, 2003, 26, 12 p. ⟨10.1046/j.1365-3040.2003.01100.x⟩
Article dans une revue hal-01833623v1

Maillard glycation of β-lactoglobulin induces conformation changes

François Chevalier , J.-M. Chobert , M. Dalgalarrondo , Y. Choiset , T. Haertle
Article dans une revue hal-02501034v1

Maillard glycation of $\beta$-lactoglobulin with several sugars: comparative study of the properties of the obtained polymers and of the substituted sites

François Chevalier , Jean-Marc Chobert , Daniel Mollé , Thomas Haertlé
Lait, 2001, 81 (5), pp.651-666. ⟨10.1051/lait:2001155⟩
Article dans une revue hal-02493839v1
Image document

Maillard glycation of $\beta$-lactoglobulin with several sugars: comparative study of the properties of the obtained polymers and of the substituted sites

François Chevalier , Jean-Marc Chobert , Daniel Mollé , Thomas Haertlé
Le Lait, 2001, 81 (5), pp.651-666. ⟨10.1051/lait:2001155⟩
Article dans une revue hal-00895361v1

Scavenging of Free Radicals, Antimicrobial, and Cytotoxic Activities of the Maillard Reaction Products of β-Lactoglobulin Glycated with Several Sugars

François Chevalier , Jean-Marc Chobert , Claude Genot , Thomas Haertlé
Journal of Agricultural and Food Chemistry, 2001, 49 (10), pp.5031-5038. ⟨10.1021/jf010549x⟩
Article dans une revue hal-02500999v1

CHARACTERIZATION OF THE MAILLARD REACTION PRODUCTS OF BETA-LACTOGLOBULIN GLUCOSYLATED IN MILD CONDITIONS

François Chevalier , Jean-Marc Chobert , Michèle Dalgalarrondo , Thomas Haertlé
Journal of Food Biochemistry, 2001, 25 (1), pp.33-55. ⟨10.1111/j.1745-4514.2001.tb00723.x⟩
Article dans une revue hal-02500986v1

Improvement of functional properties of β-lactoglobulin glycated through the Maillard reaction is related to the nature of the sugar

François Chevalier , Jean-Marc Chobert , Yves Popineau , Marie Georgette Nicolas , Thomas Haertlé
International Dairy Journal, 2001, 11 (3), pp.145-152. ⟨10.1016/S0958-6946(01)00040-1⟩
Article dans une revue hal-02501021v1

Cartilage upon ionizing radiation: from molecular processes to biological effects

Jean-Christophe Poully , François Chevalier , Thomas Schlathölter
DySoN-MultIChem 2024, Apr 2024, Tbilisi, Georgia, Georgia
Communication dans un congrès hal-04553902v1

Radiobiology at GANIL

François Chevalier
PIANOFORTE WP5 Infrastructure Workshop, INFN, Jan 2024, Catania, Sicily (Italy), Italy
Communication dans un congrès hal-04432820v1

Applications of GANIL Research Activities and Techniques

Fanny Farget , Anne-Marie Frelin , Clara Grygiel , Eloïse Dessay , François Chevalier
AccelApp'24 International Topical Meeting on Nuclear Applications of Accelerators, Mar 2024, Norfolk VA, USA, United States
Communication dans un congrès hal-04513097v1

La plateforme de Radiobiologie du CIMAP-GANIL

François Chevalier
Journées 2023 du réseau Resplandir "Réseau des Plateformes Nationales d'Irradiation pour la Dosimétrie, l'Instrumentation et la Radiobiologie", Mar 2023, Strasbourg, France
Communication dans un congrès hal-04268316v1

FLASH irradiations with carbon ions: a proof of concept at GANIL

François Chevalier
Annual meeting of the DORADIOS project, Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway, Nov 2023, Oslo, Norway
Communication dans un congrès hal-04323128v1

Phospho-proteomic analysis: preliminary results

François Chevalier
Annual meeting of the DORADIOS project, Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway, Nov 2023, Oslo, Norway
Communication dans un congrès hal-04323136v1

Plateforme iRiA pour l'accueil des expériences de radiobiologie auprès des faisceaux du GANIL

François Chevalier
Assemblée générale du GDR Mi2B « Outils et méthodes nucléaires pour la lutte contre le cancer », Oct 2023, Bordeaux, France
Communication dans un congrès hal-04268299v1

Radiosensitization of chondrosarcoma cells with PARPi

Antoine Gilbert , François Chevalier
Annual meeting of the DORADIOS project, Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway, Nov 2023, Oslo, Norway
Communication dans un congrès hal-04323153v1

Radiation-biology of radioresistant cancer models and bystander effects in a context of hadrontherapy

François Chevalier
General seminar at the Department of Radiation Biology, within the DORADIOS project, Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway, Nov 2023, Oslo, Norway
Communication dans un congrès hal-04320364v1

Programmes de recherche pré-cliniques en cours en proton et ions carbone au CIMAP

François Chevalier
Workshop Radiotransnet : Recherche Préclinique en Protonthérapie & Hadronthérapie, Radiotransnet, Nov 2022, Caen (FR), France
Communication dans un congrès hal-04268409v1

Radiosensitization of chondrosarcoma with PARP inhibitors

Antoine Gilbert , François Chevalier
Meeting of the DORADIOS RO-NO EU project, Oct 2022, Bucharest (RO), Romania
Communication dans un congrès hal-04268362v1

KRAS inhibitors in combination with X-rays or protons irradiation in NSCLC

Mathieu Césaire , François Chevalier
1er congrés de la SFBR, Nov 2022, Saint Raphael, France
Communication dans un congrès hal-04217173v1

Effets de l’hadronthérapie et des inhibiteurs de PARP sur les cellules souches cancéreuses de chondrosarcome

Antoine Gilbert , François Chevalier
1er congrés de la SFBR, Nov 2022, Saint Raphael, France
Communication dans un congrès hal-04217182v1

Plateforme d’accueil des expériences interdisciplinaires auprès des faisceaux du GANIL

François Chevalier , Jimmy Rangama
Workshop Radiotransnet : Recherche Préclinique en Protonthérapie & Hadronthérapie, Radiotransnet, Nov 2022, Caen (FR), France
Communication dans un congrès hal-04268402v1

Utilisation d'inhibiteurs KRAS comme agents de radiosensibilisation dans le CBNPC

François Chevalier
Journée Scientifique de l’axe 1 du Cancéropôle Nord-Ouest : Focus sur les cancers du Poumon et du Pancréas, Nov 2022, Paris, France
Communication dans un congrès hal-04268390v1

Radiation-induced bystander effects in Chondrosarcoma in a context of hadrontherapy: Proteomic approaches

François Chevalier
General seminar of the IFIN-HH institute, Oct 2021, Bucharest (RO), Romania
Communication dans un congrès hal-04268380v1
Image document

Impact of Hypoxia and Hadrontherapy on Radioresistant Chondrosarcoma Cancer Stem Cells

Antoine Gilbert , Julie Laurence , Marilyne Guillamin , Siamak Haghdoost , Samuel Valable
Proceeding of the ERRS 2021, Nov 2021, CAEN, France. pp.93
Communication dans un congrès hal-03757408v1

Radioresistance in Chondrosarcoma using the CIRIL-ARIA biology platform

François Chevalier
22nd COLLOQUE GANIL, Sep 2021, Autrans Meaudre en Vercors, France
Communication dans un congrès hal-04268423v1

Radioresistance and bystander signaling in Chondrosarcoma

François Chevalier
Seminar of the Brancusi PHC project FIDIA2C, Apr 2020, Bucharest (RO), Romania
Communication dans un congrès hal-04268455v1

Low dose irradiation effects on the Normal cells / Tumoral cells dialogue

François Chevalier
Seminar for Brâncusi PHC project "Partenariat Hubert Curien franco-roumain", Nov 2019, Bucharest (RO), Romania
Communication dans un congrès hal-04268478v1

Bystander Effects of human chondrosarcoma cells irradiated with accelerated ions

François Chevalier , Charlotte Lepleux , Aurélie Marie-Brasset , Mihaela Temelie , Marion Boulanger
CNB 2018 - 15th National Conference of Biophysics of the Romanian Society of Pure and Applied Biophysics, Sep 2018, Bucharest (RO), Romania
Communication dans un congrès hal-04236753v1

Bystander effect in Hadrontherapy

François Chevalier
Seminar for Sakura PHC project "Partenariat Hubert Curien franco-Japonais", Nov 2017, Tokyo (JP), Japan
Communication dans un congrès hal-04268487v1

Faits et arguments pour une toxicité extra-cellulaire des ions

François Chevalier
CIRFA 13ème Congrès Francophone de Radiobiologie SIRLAF, Dec 2017, Lyon, France
Communication dans un congrès hal-04236724v1

De l’intérêt de l’étude approfondie des cartes peptidiques massiques par MALDI-ToF: exemple d’une classe de protéines, les amylases salivaires humaines.

N Sommerer , C Hirtz , François Chevalier , D Centeno , V Rofidal
1er Symposium de Chimie et Biologie Analytiques, Sep 2005, Montpellier, France
Communication dans un congrès hal-04239206v1

Recherche préliminaire de marqueurs salivaires du diabète de type 1 chez l’homme

C Hirtz , François Chevalier , I Raingeard , Jc Egea , J Bringer
Association Dentaire Française, Nov 2004, Paris, France
Communication dans un congrès hal-04268601v1

Proteomic characterization of arabidopsis ecotypes under phosphate starvation

François Chevalier , O Martin , V Rofidal , N Sommerer , M Rossignol
Third year progress meeting EU-Framework 5 (GVE) Molecular breeding for plant growth and yield, Nov 2004, London (U.K.), United Kingdom
Communication dans un congrès hal-04268593v1

Proteomic characterization of arabidopsis ecotypes under phosphate starvation

François Chevalier , A-D Devauchelle , S Barteau , N Sommerer , M Rossignol
Second year progress meeting EU-Framework 5 (GVE) Molecular breeding for plant growth and yield, Oct 2003, Gant, Belgium
Communication dans un congrès hal-04268584v1

Proteomic characterization of arabidopsis ecotypes under phosphate starvation

François Chevalier , P Nacry , M Pata , N Sommerer , M Rossignol
First year progress meeting EU-Framework 5 (GVE) Molecular breeding for plant growth and yield, Nov 2002, Montpellier (FR), France
Communication dans un congrès hal-04268575v1

Atr kinase inhibitor augments ifn signaling following proton and carbon ion irradiation

Diana Iulia. Savu , Gro Elise Rødland , Mihaela Temelie , Ana-Maria Serban , Adrian E. Mariampillai
ICRR 2023, Aug 2023, Montréal Québec, Canada
Poster de conférence hal-04217114v1
Image document

Bystander communication between irradiated chondrosarcoma cells and non-irradiated chondrocytes: proteomic study according to doses and LETs

A Gilbert , M Tudor , D Savu , S Candéias , François Chevalier
ICRR2023 - the 17th International Congress for Radiation Research, Aug 2023, Montréal, Canada.
Poster de conférence hal-04217083v1

Investigation of proton irradiation induced effects in chondrosarcoma and bystander normal chondrocytes and endothelial cells

Tudor M. , Temelie M. , Gilbert A. , Dinischiotu A. , François Chevalier
RAP2023, May 2023, Attica, Greece
Poster de conférence hal-04217042v1

Glioblastoma and glioblastoma stem-like cancer cells radiosensitization to X-ray and carbon ions using ATM and ATR inhibitors

Mihaela Temelie , Mihaela Tudor , Ana-Maria Serban , Gro Elise Rødland , Daniela Stroe
ICRR 2023, Aug 2023, Montréal (Quebec), Canada
Poster de conférence hal-04217139v1

IFN signaling after proton and carbon ion irradiation is enhanced by inhibitors of ATR but not ATM kinase

Gro Elise Rødland , Mihaela Temelie , Ana-Maria Șerban , Nina Frederike Jeppesen Edin , Eirik Malinen
International Wolfsberg Meeting on Molecular Radiation Biology/Oncology, Jun 2023, Oslo, Norway
Poster de conférence hal-04217066v1

Hadrontherapy and PARP inhibitors effects on chondrosarcoma cancer stem cells

Antoine Gilbert , Kevin Commenchail , Samuel Valable , François Chevalier
ICRR 2023, Aug 2023, Montréal Québec, Canada
Poster de conférence hal-04217091v1

IFN signaling after proton and carbon ion irradiation is enhanced by ATR inhibition

Gro Elise Rødland , Mihaela Temelie , Ana-Maria Șerban , Adrian Eek Mariampillai , Nina Frederike Jeppesen Edin
NIRO Annual Meeting 2023, Sep 2023, Jessheim, Norway
Poster de conférence hal-04217154v1
Image document

Impact de l'hadronthérapie par ions carbone et protons sur les cellules souches cancéreuses de chondrosarcome en hypoxie

Antoine Gilbert , Juliette Montanari , Kévin Commenchail , Marilyne Guillamin , Samuel Valable
14éme journée scientifique de la cancéropôle Nord-Ouest, May 2022, Deauville, France
Poster de conférence hal-03757233v1
Image document

Analysis of ionizing radiation induced effects in radioresistant tumours and bystander normal cells

M Tudor , A Gilbert , M Temelie , A Dinischiotu , François Chevalier
46th FEBS Congress, Jul 2022, Lisbon, Portugal
Poster de conférence hal-03757272v1
Image document

Role of KRAS mutation on NSCLC resistance to X-rays and protons

Juliette Montanari , Mathieu Césaire , Antoine Gilbert , François Chevalier
ERRS 2022 - 47th Annual Meeting of the European Radiation Research Society, Sep 2022, Catania, Italy.
Poster de conférence hal-03808183v1
Image document

Presentation of the CIRIL / radiation biology platform dedicated for experiments with the GANIL facility

Chevalier François , Violaine Vizcaino , Jean-Christophe Poully , Alain Mery , Jimmy Rangama
ERRS 2021, Nov 2021, CAEN, France
Poster de conférence hal-03757189v1
Image document

Sensitization of chondrosarcoma cells with PARP inhibitor and impact on cancer stem cells

Mathieu Césaire , Antoine Gilbert , Julie Laurence , Nicolas Elie , Florence Giffard
ERRS 2021, Nov 2021, CAEN, France
Poster de conférence hal-03757108v1
Image document

Proteomic analysis of bystander effects in chondrosarcoma cells

Antoine Gilbert , Mihaela Tudor , Charlotte Lepleux , V. Rofidal , Sonia Hem
45th Annual Meeting of the European Radiation Research Society, Sep 2020, Lund, Sweden. , pp.123
Poster de conférence hal-03144446v1
Image document

P47. Proteomic analysis of the Radiation-Induced Bystander Effects between low-dose irradiated Chondrosarcoma cells and Bystander Chondrocytes

Charlotte Lepleux , Valerie Rofidal , Sonia Hem , Christine Almunia , J. Armengaud
4th European Radiation Protection Week, Oct 2019, Stockholm, Sweden
Poster de conférence hal-03144468v1
Image document

Bystander effectors of chondrosarcoma cells irradiated at different LET impair proliferation of chondrocytes

Charlotte Lepleux , Aurélie Marie-Brasset , Emilie Brotin , Tetsuo Nakajima , Diana Savu
ENLIGHT Annual Meeting and Training 2019, Jul 2019, Caen, France
Poster de conférence hal-03144584v1
Image document

High LET Radiation Overcomes in vitro Resistance to X-rays of Chondrosarcoma Cell Lines

Dounia Houria Hamdi , Charlotte Lepleux , Agnès Nicolle , Guillaume Varès , Paul Lesueur
ENLIGHT Annual Meeting and Training 2019, Jul 2019, Caen, France
Poster de conférence hal-03144579v1
Image document

Proteomic analysis of the Radiation-Induced Bystander Effects

Charlotte Lepleux , François Chevalier
ENLIGHT Annual Meeting and Training 2019, Jul 2019, Caen, France
Poster de conférence hal-03144600v1
Image document

P23 - Bystander effectors of chondrosarcoma cells irradiated at different LET impair proliferation of chondrocytes

Charlotte Lepleux , Diana Savu , François Chevalier
16th International Congress of Radiation Research, Aug 2019, Manchester, United Kingdom
Poster de conférence hal-03144483v1
Image document

Sensitization of chondrosarcoma cells with PARP inhibitor and high-LET radiation

Mathieu Césaire , Utpal Ghosh , Jean Baptiste Austry , Francesco Cammarata , Laurent Castera
ENLIGHT Annual Meeting and Training 2019, Jul 2019, Caen, France
Poster de conférence hal-03144597v1
Image document

Discriminating sub-population responses of a mixture of human cell lines by proteogenomics

Christine Almunia , Yannick Cogne , Olivier Pible , Charlotte Lepleux , François Chevalier
43rd FEBS Congress, Biochemistry Forever, Prague, Czech Republic, July 7-12, 2018, Jul 2018, Prague (CZ), France
Poster de conférence hal-04475761v1
Image document

Study of bystander signals emitted by chondrosarcoma cells irradiated in vitro with X-rays and carbon ions

François Chevalier , Charlotte Lepleux
ERRS and GBS 2017 - the Joint 43rd European Radiation Research Society (ERRS) and 20th German Society for Biological Radiation Research (GBS) Annual Meetings, Sep 2017, Essen, Germany.
Poster de conférence hal-04236739v1
Image document

Radio-sensitization of chondrosarcoma cells by PARP inhibitors

Utpal Ghosh , Jean-Baptiste Austry , Francesco Paulo Cammarata , Renata Leanza , Pietro Pisciotta
ERRS and GBS 2017 - the Joint 43rd European Radiation Research Society (ERRS) and 20th German Society for Biological Radiation Research (GBS) Annual Meetings", Sep 2017, Essen, Germany
Poster de conférence hal-04236732v1
Image document

Proliferation impairment of chondrosarcoma cells irradiated with X-Rays and carbon-ion beams

François Chevalier , Dounia Houria Hamdi , Yvonne De Jong , Judith V. M. G.. Bovée , Yannick Saintigny
PTCOG55 2016 - the 55th Annual Meeting for the Particle Therapy Cooperative Group, May 2016, Prague, Czech Republic.
Poster de conférence hal-04236718v1
Image document

Méta-analyses protéogénomiques d’un effet Bystander radio-induit aux faibles doses

Charlotte Lepleux , Christine Almunia , Olivier Pible , Diana Tronic-Le Roux , Jean Armengaud
Congrès SFEAP 2016 - Congrès de la Société Française d'Electrophorèse et d’Analyse Protéomique, Oct 2016, Chambéry, France.
Poster de conférence hal-04236701v1
Image document

P046: Engineering of a 3D cartilage model: study of healthy cartilage exposition during hadrontherapy

François Chevalier , Dounia Hamdi , Yannick Saintigny , Florence Legendre , Magali Demoor
PTCOG 53 - Particle Therapy Co-Operative Group, Jun 2014, Shanghai, China.
Poster de conférence hal-04235720v1
Image document

Analysis of targeted effects of ionizing radiations on reconstructed human healthy cartilage and chondrosarcoma

Dounia H. Hamdi , François Chevalier , Jean-Emmanuel Groetz , Jl Lefaix , Yannick Saintigny
60th annual meeting of the Radiation Research Society, Sep 2014, Las Vegas, United States.
Poster de conférence hal-04248682v1

In vitro engineering of human cartilage: a preclinical model relevant to exposition of surrounding healthy tissues during radiotherapy

François Chevalier , Dounia Hamdi , Jean-Louis Lefaix
Workshop on 3D culture models for radiation and cancer research, Sep 2013, Rotterdam (NL), Netherlands
Poster de conférence hal-04235688v1
Image document

Proteomic comparison of ALT and Telomerase+ Glioma Stem cells

François Chevalier , David Silvestre , Maya Jeitany , Jordane Depagne , Pascale Bertrand
HUPO 2011 10th World Congress, Sep 2011, Genève, Switzerland.
Poster de conférence hal-04244543v1
Image document

Analysis of proteins in the secretome of the mouse developing testis

François Chevalier , Marie-Justine Guerquin , Jordane Depagne , Pascale Bertrand , René Habert
SMAP 2009 - Congrès Français de Spectrométrie de Masse et d’Analyse Protéomique, Sep 2009, Dijon, France
Poster de conférence hal-04244517v1

Analysis of proteins in the secretome of the mouse developing testis

François Chevalier , Marie-Justine Guerquin , Jordane Depagne , Pascale Bertrand , René Habert
5ème rencontre Plasticité et Instabilité des Génomes PIG-5, Nov 2009, Marcoule, France
Poster de conférence hal-04484368v1
Image document

Research of diffusible factors secreted during radio-induced mammary tumor cell death

François Chevalier , Jordan Depagne , Sylvie Chevillard , Pascale Bertrand , Jérôme Lebeau
25ème congrès de la SFEAP, Oct 2008, Tour, France
Poster de conférence hal-04244503v1
Image document

Study of protein complex formation during storage and gelation of UHT milk

E Armaforte , François Chevalier , M. F. Caboni , M. A. E. Auty , A. L. Kelly
The 38th UCC Annual Research Conference hosts on Food, Nutrition and Consumer Sciences, Sep 2008, Cork, Ireland
Poster de conférence hal-04244482v1
Image document

Proteins and proteolysis in pre-term and term human milk samples

François Chevalier , Emanuele Armaforte , A Ryan , Al Kelly
The 38th UCC Annual Research Conference hosts on Food, Nutrition and Consumer Sciences, Sep 2008, Cork, Ireland
Poster de conférence hal-04244470v1
Image document

Cytokin in action is linked to oxidative stress as shown by proteome analysis in $Arabidopsis$

P Vanova , François Chevalier , V Rofidal , M Rossignol , J Malbeck
19th annual meeting of the International Plant growth substance Association, Jul 2007, Puerto Vallarta, Mexico
Poster de conférence hal-04239178v1
Image document

Proteomic comparison of human milk from term and pre-term mothers

François Chevalier , Emanuele Armaforte , Erika Curran , C. Antony Ryan , Alan L. Kelly
International Dairy Federation: World Dairy Summit 2007, Sep 2007, Dublin, Ireland
Poster de conférence hal-04244460v1
Image document

Proteomic changes in milk after heat treatment

François Chevalier , Katharina Hinz , Alan L. Kelly
The IDF World Dairy Summit, Sep 2007, Dublin, Ireland.
Poster de conférence hal-04244453v1

Proteomic study of changes in milk protein profile with increasing somatic cell count

K Hinz , François Chevalier , B Larsen L , M Bruckmaier R , L Kelly A
International Dairy Federation: World Dairy Summit 2007, Sep 2007, Dublin, Ireland
Poster de conférence hal-04244443v1
Image document

Unexpected proteomics and biochemical complexity of human salivary $\alpha$-amylases in 2D gels

Nicolas Sommerer , Christophe Hirtz , Jean-Pascal Gimeno , François Chevalier , Delphine Centeno
17th International Mass Spectrometry Conference, Aug 2006, Prague, Czech Republic.
Poster de conférence hal-04239153v1

Salivary protein profiling in type 1 diabetes using proteomic tools

C Hirtz , François Chevalier , N. Sommerer , I Raingeard , J Bringer
IADR Pan European Federation 2006, Sep 2006, Dublin (Ireland), Ireland
Poster de conférence hal-04239185v1
Image document

Link between cytokinins, oxidative stress and jasmonic acid as revealed by proteome analysis in $Arabidopsis$

P Vanova , François Chevalier , V Rofidal , M Rossignol , J Malbeck
XV FESPB Congress - Federation of European Societies of Plant Biology, Jul 2006, Lyon, France.
Poster de conférence hal-04239138v1
Image document

Modulation de l’expression de protéines salivaires lors du diabète de type 1

Christophe Hirtz , François Chevalier , Sandrine Chay , Isabelle Raingeard , Jacques Bringer
1er Symposium de Chimie et Biologie Analytiques, Sep 2005, Montpellier, France
Poster de conférence hal-04239199v1
Image document

Effects of elevated endogenous cytokinin levels on the $Arabidopsis\ thaliana$ proteome

Pavlina Vanova , François Chevalier , Valérie Rofidal , Michel Rossignol , Jiri Malbeck
ACPD 2005 - Auxins And Cytokinins In Plant Development International symposium, Jul 2005, Prague, Czech Republic.
Poster de conférence hal-04239116v1
Image document

Identification des protéines par MALDI-TOF après électrophorèse 2D : Performance et compatibilité comparaison du bleu colloïdal (CCB), nitrate d'argent (SN), Spyro$^{TM}$ Ruby (SR) and Deep Purple$^{TM}$ (DP)

Nicolas Sommerer , François Chevalier , Valérie Rofidal , Delphine Centeno , Marc Tauzin
1er Symposium de Chimie et Biologie Analytiques, Sep 2005, Montpellier, France
Poster de conférence hal-04239209v1
Image document

Human saliva proteome reveal unexpected forms of alpha-amylase.

C. Hirtz , François Chevalier , D. Centeno , V. Rofidal , J. C. Egea
Joint Meeting of the Continental European (CED) and the Scandinavian (NOF) Divisions of IADR, Sep 2005, Amsterdam (Hollande), Netherlands
Poster de conférence hal-04239129v1

Scavenging of free radicals, anti-microbial and cytotoxic activities of the maillard reaction products of ß-lactoglobulin glycated with various sugars

François Chevalier , Jean-Marc Chobert , Claude Genot , Thomas Haertlé
Thermally processed food : possible health implications Working Groups & Management Committee Meetings, Apr 2005, Larnaca, Cyprus
Poster de conférence hal-04239193v1
Image document

Comparative proteomics to reveal naturally occurring variability in Arabidopsis thaliana accessions.

François Chevalier , Anne-Dominique Devauchelle , Samuel Barteau , Olivier Martin , Nicolas Sommerer
Proteomic Forum München, Sep 2003, Munich, Germany
Poster de conférence hal-04239084v1
Image document

Glycation leads to polymerization and tryptic resistance of beta-lactoglobulin

François Chevalier , Jean-Marc Chobert , Thomas Haertle
Milk protein conference, Mar 2000, Vinstra, Norway
Poster de conférence hal-04239052v1
Image document

Radiobiology of Combining Radiotherapy with Other Cancer Treatment Modalities

Vidhula Ahire , Niloefar Ahmadi Bidakhvidi , Tom Boterberg , Pankaj Chaudhary , François Chevalier
Radiobiology Textbook, Springer International Publishing, pp.311 - 386, 2023, ⟨10.1007/978-3-031-18810-7_6⟩
Chapitre d'ouvrage hal-04221267v1
Image document

Basic Concepts of Radiation Biology

Ans Baeyens , Ana Margarida Abrantes , Vidhula Ahire , Elizabeth Ainsbury , Sarah Baatout
Radiobiology Textbook, Springer International Publishing, pp.25-81, 2023, ⟨10.1007/978-3-031-18810-7_2⟩
Chapitre d'ouvrage hal-04221255v1

Identification of factors involved in neurogenesis recovery following irradiation of the adult mouse subventricular zone, a preliminary study

François Chevalier , A Chicheportiche , M Daynac , J Depagne , P Bertrand
Tsz-Kwong Man and Ricardo J. Flores. Proteomics – Human Diseases and Protein Functions, InTech, pp.327-346, 2012, 978-953-307-832-8
Chapitre d'ouvrage hal-04239262v1

Analytical Methods: Electrophoresis

François Chevalier
McSweeney PLH. Encyclopedia of Dairy Sciences, Second Edition, vol. 1, Academic Press, pp.185-192, 2011
Chapitre d'ouvrage hal-04239245v1

What future for “Gel-based proteomic” approaches?

François Chevalier
Giselle C. Rancourt. Proteomics: Methods, Applications and Limitations, Protein Biochemistry, Synthesis, Structure and Cellular Functions, Nova Science Publishers, pp.31-52, 2011, 978-1-61668-691-8
Chapitre d'ouvrage hal-04239235v1

Milk Proteins : Proteomics

François Chevalier
McSweeney PLH. Encyclopedia of Dairy Sciences, Second Edition, vol. 1, Academic Press, pp.843-847, 2011
Chapitre d'ouvrage hal-04239251v1

Analytical Methods / Mass Spectrometric Methods

François Chevalier , Nicolas Sommerer
Encyclopedia of Dairy Sciences, Academic Press, 2011, 978-0-12-374407-4. ⟨10.1016/B978-0-12-374407-4.00019-4⟩
Chapitre d'ouvrage hal-02805378v1

Visible and Fluorescent Staining of Two-Dimensional Gels

François Chevalier , Valerie Rofidal , Michel Rossignol
Plant Proteomics, 355, Humana Press, pp.145-156, 2007, ⟨10.1385/1-59745-227-0:145⟩
Chapitre d'ouvrage hal-02501127v1

Interfacial properties of glycated ß-lactoglobulin

François Chevalier , J-M Chobert , T Haertlé
Marc Anton. Recent Advances in Agricultural and Food Chemistry, Research Signpost, pp.117-125, 2002, 81-7736-102-3
Chapitre d'ouvrage hal-04239224v1