Francois Chevalier

François Chevalier UMR6252 CIMAP Team leader Group ARIA
44 %
Libre accès
204
Documents
Affiliations actuelles
  • Accueil et Recherche en Radiobiologie des Ions Accélérés (ARIA)
  • Centre de recherche sur les Ions, les MAtériaux et la Photonique (CIMAP - UMR 6252)
Contact

Présentation

Domaines de recherche

Cancer Biologie cellulaire Génomique, Transcriptomique et Protéomique [q-bio.GN] Biochimie, Biologie Moléculaire

Compétences

hadronbiologie

Publications

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Publications

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Radiobiology Contributions and Perspectives in Hadron Therapy, with a focus on carbon ions: Report from the workshop Hadron therapy for life, Caen, March 2025

Siamak Haghdoost , Juliette Thariat , Iluliana Toma-Dasu , Benjamin Frey , Claire Rodriguez-Lafrasse et al.

International Journal of Particle Therapy, 2026, 19, pp.101289. ⟨10.1016/j.ijpt.2025.101289⟩

Article dans une revue hal-05386921v1
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Particle Therapy to Overcome Cancer Radiation Resistance: “ARCHADE” Consortium Updates in Radiation Biology

Samuel Valable , Mathieu Césaire , Kilian Lecrosnier , Antoine Gilbert , Mihaela Tudor et al.

Cancers, 2025, 17 (9), pp.1580. ⟨10.3390/cancers17091580⟩

Article dans une revue hal-05064518v1

In vitro flash effect as a function of ultra-high dose rates with proton beam

Mihaela Temelie , Mateusz Sitarz , Mihaela Tudor , Kilian Lecrosnier , Mihai Radu et al.

International Journal of Particle Therapy, 2025, 17, pp.101053. ⟨10.1016/j.ijpt.2025.101053⟩

Article dans une revue hal-05397419v1
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Impact of KRAS G12C mutation on the efficacy of chemoradiotherapy in patients with unresectable stage II or III non-small cell lung cancer

Jean Cabon , Delphine Lerouge , Sebastien Thureau , Jacques Balosso , Marin Guigo et al.

Frontiers in Oncology, 2025, 15, ⟨10.3389/fonc.2025.1675825⟩

Article dans une revue hal-05390494v1
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Effect of reoxygenation on radioresistance of chronically hypoxic A549 non-small cell lung cancer (NSCLC) cells following X-ray and carbon ion exposure

Hasan Nisar , Bikash Konda , Marie Denise Hoffmann , Frederik Labonté , Maryam Arif et al.

International Journal of Molecular Sciences, 2025, 26 (18), pp.9153. ⟨10.3390/ijms26189153⟩

Article dans une revue hal-05300963v1
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Assessing the Relative Contribution of DSB Repair Proteins as a Function of LET

Francisco D.C. Guerra Liberal , Shannon J Thompson , Lydia L Gardner , Jason L Parsons , François Chevalier et al.

International Journal of Particle Therapy, 2025, 17, pp.101198. ⟨10.1016/j.ijpt.2025.101198⟩

Article dans une revue hal-05222162v1

Multi-proteomics investigation of the early response to X-rays and carbon ion irradiations of HeLa cells

Ousseynou Ben Diouf , Antoine Gilbert , Benoit Bernay , Mamadou Soumboundou , Cheikh Sall et al.

Integrative biology, 2025, 17, ⟨10.1093/intbio/zyaf008⟩

Article dans une revue hal-05125143v1
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CpG Methylation Protects DNA against Ionizing Radiation

Leo Sala , Tereza Zápotocká , Jana Šáchová , Václav Olšanský , David Chvátil et al.

Journal of Physical Chemistry B, 2025, ⟨10.1021/acs.jpcb.5c04043⟩

Article dans une revue hal-05221620v1
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Use of patient-derived tumor organoids from head and neck squamous cell carcinoma for the evaluation of the differential effect of carbon ions over X-rays

Marion Perréard , Romane Florent , Jordane Divoux , Vianney Bastit , Lucie Lecouflet et al.

Radiotherapy & Oncology, 2025, 210, pp.111026. ⟨10.1016/j.radonc.2025.111026⟩

Article dans une revue hal-05213124v1
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Interferon signaling is enhanced by ATR inhibition in glioblastoma cells irradiated with X-rays, protons or carbon ions

Gro Elise Rødland , Mihaela Temelie , Adrian Eek Mariampillai , Ana Maria Serban , Nina Frederike Jeppesen Edin et al.

Radiotherapy & Oncology, 2025, 203, pp.110669. ⟨10.1016/j.radonc.2024.110669⟩

Article dans une revue (data paper) hal-04865839v1
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Radiosensitizing Effect of PARP Inhibition on Chondrosarcoma and Chondrocyte Cells Is Dependent on Radiation LET

Antoine Gilbert , Mihaela Tudor , Amandine Delaunay , Raphaël Leman , Julien Levilly et al.

Biomolecules, 2024, 14 (9), pp.1071. ⟨10.3390/biom14091071⟩

Article dans une revue hal-04679720v1
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Hypoxia Modulates Radiosensitivity and Response to Different Radiation Qualities in A549 Non-Small Cell Lung Cancer (NSCLC) Cells

Hasan Nisar , Frederik M Labonté , Marie Denise Roggan , Claudia Schmitz , François Chevalier et al.

International Journal of Molecular Sciences, 2024, 25 (2), pp.1010. ⟨10.3390/ijms25021010⟩

Article dans une revue hal-04409075v1
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Pilot screening of potential matrikines resulting from collagen breakages through ionizing radiation

Juliette Montanari , Lucas Schwob , Aurélie Marie-Brasset , Claire Vinatier , Charlotte Lepleux et al.

Radiation and Environmental Biophysics, 2024, ⟨10.1007/s00411-024-01086-z⟩

Article dans une revue hal-04672742v1
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Applications of GANIL Research Activities and Techniques

Fanny Farget , Patricia Roussel-Chomaz , François Chevalier , Eloïse Dessay , Diane Doré et al.

Nuclear Science and Technology Open Research, 2024, 2, pp.79. ⟨10.12688/nuclscitechnolopenres.17612.1⟩

Article dans une revue hal-05387290v1
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Phospho-proteomics analysis of early response to X-ray irradiation reveals molecular mechanism potentially related to U251 cell radioresistance

Ousseynou Ben Diouf , Antoine Gilbert , Benoit Bernay , Randi G Syljuåsen , Mihaela Tudor et al.

Proteomes, 2024, 13 (1), pp.1. ⟨10.3390/proteomes13010001⟩

Article dans une revue (data paper) hal-04865879v1
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Potential Benefits of Combining Proton or Carbon Ion Therapy with DNA Damage Repair Inhibitors

Gro Elise Rødland , Mihaela Temelie , Adrian Eek Mariampillai , Sissel Hauge , Antoine Gilbert et al.

Cells, 2024, 13 (12), pp.1058. ⟨10.3390/cells13121058⟩

Article dans une revue (article de synthèse) hal-04617893v1
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NF-κB in the Radiation Response of A549 Non-Small Cell Lung Cancer Cells to X-rays and Carbon Ions under Hypoxia

Hasan Nisar , Paulina Sanchidrián González , Frederik Labonté , Claudia Schmitz , Marie Roggan et al.

International Journal of Molecular Sciences, 2024, 25 (8), pp.4495. ⟨10.3390/ijms25084495⟩

Article dans une revue hal-04553905v1

Radiation‐Induced Transfer of Charge, Atoms and Energy within Isolated Biomolecular Systems

François Chevalier , Thomas Schlathölter , Jean-Christophe Poully

ChemBioChem, 2023, ⟨10.1002/cbic.202300543⟩

Article dans une revue hal-04216855v1
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A Longitudinal Study of Individual Radiation Responses in Pediatric Patients Treated with Proton and Photon Radiotherapy, and Interventional Cardiology: Rationale and Research Protocol of the HARMONIC Project

Maria Grazia Andreassi , Nadia Haddy , Mats Harms-Ringdahl , Jonica Campolo , Andrea Borghini et al.

International Journal of Molecular Sciences, 2023, 24 (9), pp.8416. ⟨10.3390/ijms24098416⟩

Article dans une revue (article de synthèse) hal-04103396v1
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In vitro hyperspectral biomarkers of human chondrosarcoma cells in nanoparticle-mediated radiosensitization using carbon ions

Mihaela Tudor , Roxana Cristina Popescu , Raluca D Negoita , Antoine Gilbert , Mihaela A Ilisanu et al.

Scientific Reports, 2023, 13 (1), pp.14878. ⟨10.1038/s41598-023-41991-9⟩

Article dans une revue hal-04202858v1
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Chondrosarcoma Resistance to Radiation Therapy: Origins and Potential Therapeutic Solutions

Antoine Gilbert , Mihaela Tudor , Juliette Montanari , Kevin Commenchail , Diana Iulia Savu et al.

Cancers, 2023, 15 (7), pp.1962. ⟨10.3390/cancers15071962⟩

Article dans une revue hal-04058836v1
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Radioresistance of Non-Small Cell Lung Cancers and Therapeutic Perspectives

Mathieu Césaire , Juliette Montanari , Hubert Curcio , Delphine Lerouge , Radj Gervais et al.

Cancers, 2022, 14 (12), pp.2829. ⟨10.3390/cancers14122829⟩

Article dans une revue hal-03697588v1
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Label-Free Direct Mass Spectrometry Analysis of the Bystander Effects Induced in Chondrocytes by Chondrosarcoma Cells Irradiated with X-rays and Carbon Ions

Antoine Gilbert , Valentin Payet , Benoît Bernay , Elisabeth Chartier-Garcia , Isabelle Testard et al.

Frontiers in Bioscience-Landmark, 2022, 27 (9), pp.277. ⟨10.31083/j.fbl2709277⟩

Article dans une revue hal-03814877v1

CYCLHAD: A French Facility Dedicated for Research and Treatment in Hadrontherapy

François Chevalier , P. Lesueur , G. Gaubert

Nuclear Physics News, 2022, 32 (2), pp.27-31. ⟨10.1080/10619127.2022.2063002⟩

Article dans une revue hal-03759681v1

Avoidance or adaptation of radiotherapy in patients with cancer with Li-Fraumeni and heritable TP53-related cancer syndromes

Juliette Thariat , François Chevalier , Daniel Orbach , Luc Ollivier , Pierre-Yves Marcy et al.

Lancet Oncology, 2021, 22 (12), pp.e562-e574. ⟨10.1016/S1470-2045(21)00425-3⟩

Article dans une revue hal-03464420v1
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A Proteomic Study Suggests Stress Granules as New Potential Actors in Radiation-Induced Bystander Effects

Mihaela Tudor , Antoine Gilbert , Charlotte Lepleux , Mihaela Temelie , Sonia Hem et al.

International Journal of Molecular Sciences, 2021, 22 (15), pp.7957. ⟨10.3390/ijms22157957⟩

Article dans une revue hal-03301338v1
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Counteracting Radio-Resistance Using the Optimization of Radiotherapy

François Chevalier

International Journal of Molecular Sciences, 2020, 21 (5), pp.1767. ⟨10.3390/ijms21051767⟩

Article dans une revue hal-02503021v1

A multimodal treatment of carbon ions irradiation, miRNA-34 and mTOR inhibitor specifically control high-grade chondrosarcoma cancer stem cells

Guillaume Vares , Vidhula Ahire , Shigeaki Sunada , Eun Ho Kim , Sei Sai et al.

Radiotherapy & Oncology, 2020, 150, pp.253-261. ⟨10.1016/j.radonc.2020.07.034⟩

Article dans une revue hal-03298410v1
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Hadrontherapy Interactions in Molecular and Cellular Biology

Juliette Thariat , Samuel Valable , Carine Laurent , Siamak Haghdoost , Elodie A. Pérès et al.

International Journal of Molecular Sciences, 2020, 21 (1), pp.133. ⟨10.3390/ijms21010133⟩

Article dans une revue hal-02429129v1
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Sensitization of chondrosarcoma cells with PARP inhibitor and high-LET radiation

Mathieu Césaire , Utpal Ghosh , Jean-Baptiste Austry , Etienne Müller , Francesco Paolo Cammarata et al.

Journal of Bone Oncology, 2019, 17, pp.100246. ⟨10.1016/j.jbo.2019.100246⟩

Article dans une revue hal-02332712v1
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High LET Radiation Overcomes In Vitro Resistance to X-Rays of Chondrosarcoma Cell Lines

François Chevalier , Dounia Houria Hamdi , Charlotte Lepleux , Mihaela Temelie , Anaïs Nicol et al.

Technology in Cancer Research and Treatment, 2019, 18, pp.153303381987130. ⟨10.1177/1533033819871309⟩

Article dans une revue hal-02333914v1
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Bystander effectors of chondrosarcoma cells irradiated at different LET impair proliferation of chondrocytes

Charlotte Lepleux , Aurélie Marie-Brasset , Mihaela Temelie , Marion Boulanger , Émilie Brotin et al.

Journal of Cell Communication and Signaling, 2019, 13 (3), pp.343-356. ⟨10.1007/s12079-019-00515-9⟩

Article dans une revue inserm-02125509v1
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Combining PARP inhibition, radiation, and immunotherapy: A possible strategy to improve the treatment of cancer?

Mathieu Césaire , Juliette Thariat , Serge M. Candéias , Dinu Stefan , Yannick Saintigny et al.

International Journal of Molecular Sciences, 2018, 19 (12), pp.3793. ⟨10.3390/ijms19123793⟩

Article dans une revue hal-01948336v1
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Radiosensitization Effect of Talazoparib, a Parp Inhibitor, on Glioblastoma Stem Cells Exposed to Low and High Linear Energy Transfer Radiation

Paul Lesueur , François Chevalier , Elias A. El-Habr , Marie-Pierre Junier , Hervé Chneiweiss et al.

Scientific Reports, 2018, 8, pp.3664. ⟨10.1038/s41598-018-22022-4⟩

Article dans une revue hal-01738585v1

Review of the Mechanisms Involved in the Abscopal Effect and Future Directions with a Focus on Thymic Carcinoma

Paul Lesueur , François Chevalier , Dinu Stefan , Jean-Louis Habrand , Delphine Lerouge et al.

Tumori, 2017, 103 (3), pp.217-222. ⟨10.5301/tj.5000616⟩

Article dans une revue hal-02503009v1
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Poly-(ADP-ribose)-polymerase inhibitors as radiosensitizers: a systematic review of pre-clinical and clinical human studies

Paul Lesueur , François Chevalier , Jean-Baptiste Austry , Waisse Waissi , Hélène Burckel et al.

Oncotarget, 2017, 8 (40), ⟨10.18632/oncotarget.19079⟩

Article dans une revue hal-02493848v1
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Translational research in radiobiology in the framework of France HADRON national collaboration

Claire Rodriguez-Lafrasse , Yannick Saintigny , François Chevalier , Myriam Bernaudin , Carine Laurent et al.

Translational Cancer Research, 2017, 6 (S5), pp.S795-S806. ⟨10.21037/tcr.2017.06.33⟩

Article dans une revue hal-01610093v1
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Poly-(ADP-ribose)-polymerase inhibitors as radiosensitizers: a systematic review of pre-clinical and clinical human studies

Paul Lesueur , François Chevalier , Jean-Baptiste Austry , Waisse Waissi , Hélène Burckel et al.

Oncotarget, 2017, 8 (40), pp.69105-69124. ⟨10.18632/oncotarget.19079]⟩

Article dans une revue cea-01938036v1
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Comparable Senescence Induction in Three-dimensional Human Cartilage Model by Exposure to Therapeutic Doses of X-rays or C-ions

Dounia Hamdi , François Chevalier , Jean-Emmanuel Groetz , Florent Durantel , Jean-Yves Thuret et al.

International Journal of Radiation Oncology, Biology, Physics, 2016, 95 (1), pp.139 - 146. ⟨10.1016/j.ijrobp.2016.02.014⟩

Article dans une revue cea-01938049v1
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A threshold of endogenous stress is required to engage cellular response to protect against mutagenesis.

Yannick Saintigny , François Chevalier , Anne Bravard , Elodie Dardillac , David Laurent et al.

Scientific Reports, 2016, 6, pp.29412. ⟨10.1038/srep29412⟩

Article dans une revue hal-01594490v1
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Dosimetry for radiobiology experiments at GANIL

Florent Durantel , Emmanuel Balanzat , Amine Cassimi , François Chevalier , Yvette Ngono-Ravache et al.

Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2016, 816, pp.70 - 77. ⟨10.1016/j.nima.2016.01.052⟩

Article dans une revue cea-01938057v1

Proteomic overview and perspectives of the radiation-induced bystander effects

François Chevalier , Dounia Houria Hamdi , Yannick Saintigny , Jean-Louis Lefaix

Mutation Research/Reviews in Mutation Research, 2015, 763, pp.280-293. ⟨10.1016/j.mrrev.2014.11.008⟩

Article dans une revue hal-02503001v1

Impact of Therapeutic Irradiation on Healthy Articular Cartilage

Yannick Saintigny , Séverine Cruet-Hennequart , Dounia Houria Hamdi , François Chevalier , Jean-Louis Lefaix

Radiation Research, 2015, 183 (2), pp.135-146. ⟨10.1667/rr13928.1⟩

Article dans une revue hal-02493854v1
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In vitro engineering of human 3D chondrosarcoma: a preclinical model relevant for investigations of radiation quality impact

Dounia Hamdi , Sofia Barbieri , François Chevalier , Jean-Emmanuel Groetz , Florence Legendre et al. Article dans une revue hal-01315021v1

Proteomic Comparison of Equine and Bovine Milks on Renneting

Therese Uniacke-Lowe , Francois Chevalier , Sonia Hem , Patrick F. Fox , Daniel M. Mulvihill

Journal of Agricultural and Food Chemistry, 2013, 61 (11), pp.2839 - 2850. ⟨10.1021/jf3045846⟩

Article dans une revue hal-01837537v1

Impairing the microRNA biogenesis pathway induces proteome modifications characterized by size bias and enrichment in antioxidant proteins

Delphine Peric , Jean Labarre , François Chevalier , Germain Rousselet

Proteomics, 2012, 12 (14), pp.2295-2302. ⟨10.1002/pmic.201100461⟩

Article dans une revue istex hal-02502836v1

Accumulation of cyclophilin A isoforms in conditioned medium of irradiated breast cancer cells

François Chevalier , Jordane Dépagne , Sonia Hem , Sylvie Chevillard , Julie Bensimon et al.

Proteomics, 2012, 12 (11), pp.1756-1766. ⟨10.1002/pmic.201100319⟩

Article dans une revue istex hal-02502815v1

Effect of high-pressure treatment of milk for cheese manufacture on proteolysis, lipolysis, texture and functionality of Cheddar cheese during ripening

Daniela Voigt , François Chevalier , John Donaghy , Margaret Patterson , Michael Qian et al.

Innovative Food Science & Emerging Technologies / Innovative Food Science and Emerging Technologies , 2012, 13, pp.23-30. ⟨10.1016/j.ifset.2011.10.004⟩

Article dans une revue istex hal-02502753v1
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Technical updates to basic proteins focalization using IPG strips

Jordane Dépagne , François Chevalier

Proteome Science, 2012, 10 (1), pp.54. ⟨10.1186/1477-5956-10-54⟩

Article dans une revue hal-02502828v1

Bcl-2 Inhibits Nuclear Homologous Recombination by Localizing BRCA1 to the Endomembranes

C. Laulier , A. Barascu , J. Guirouilh-Barbat , G. Pennarun , C. Le Chalony et al.

Cancer Research, 2011, 71 (10), pp.3590-3602. ⟨10.1158/0008-5472.CAN-10-3119⟩

Article dans une revue hal-02502797v1

Proteomic analysis of Arabidopsis thaliana ecotypes with contrasted root architecture in response to phosphate deficiency

François Chevalier , Michel Rossignol

Journal of Plant Physiology, 2011, 168 (16), pp.1885-1890. ⟨10.1016/j.jplph.2011.05.024⟩

Article dans une revue istex hal-02501132v1

Proteins and proteolysis in pre-term and term human milk and possible implications for infant formulae

Emanuele Armaforte , Erika Curran , Thom Huppertz , C. Anthony Ryan , Maria Caboni et al.

International Dairy Journal, 2010, 20 (10), pp.715-723. ⟨10.1016/j.idairyj.2010.03.008⟩

Article dans une revue istex hal-02502695v1

Effect of high-pressure treatment on microbiology, proteolysis, lipolysis and levels of flavour compounds in mature blue-veined cheese

Daniela Voigt , François Chevalier , Michael Qian , Alan Kelly

Innovative Food Science & Emerging Technologies / Innovative Food Science and Emerging Technologies , 2010, 11 (1), pp.68-77. ⟨10.1016/j.ifset.2009.10.009⟩

Article dans une revue istex hal-02502718v1

Standard Dyes for Total Protein Staining in Gel-Based Proteomic Analysis

François Chevalier

Materials, 2010, 3 (10), pp.4784-4792. ⟨10.3390/ma3104784⟩

Article dans une revue hal-02502783v1

Proteomic Quantification of Disulfide-Linked Polymers in Raw and Heated Bovine Milk

François Chevalier , Alan Kelly

Journal of Agricultural and Food Chemistry, 2010, 58 (12), pp.7437-7444. ⟨10.1021/jf1010879⟩

Article dans une revue hal-02502703v1
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Highlights on the capacities of "Gel-based" proteomics

François Chevalier

Proteome Science, 2010, 8 (1), pp.23. ⟨10.1186/1477-5956-8-23⟩

Article dans une revue hal-02502775v1

Use of Reducing/Nonreducing Two-Dimensional Electrophoresis for the Study of Disulfide-Mediated Interactions between Proteins in Raw and Heated Bovine Milk

François Chevalier , Christophe Hirtz , Nicolas Sommerer , Alan Kelly

Journal of Agricultural and Food Chemistry, 2009, 57 (13), pp.5948-5955. ⟨10.1021/jf900518n⟩

Article dans une revue hal-02502451v1

Effect of high-pressure homogenisation on rheological properties of rennet-induced skim milk and standardised milk gels

Kristina Lodaite , François Chevalier , Emanuele Armaforte , Alan Kelly

Journal of Dairy Research, 2009, 76 (3), pp.294-300. ⟨10.1017/S0022029909004117⟩

Article dans une revue istex hal-02502466v1

Use of Reducing/Nonreducing Two-Dimensional Electrophoresis for the Study of Disulfide-Mediated Interactions between Proteins in Raw and Heated Bovine Milk

François Chevalier , Christophe Hirtz , Nicolas Sommerer , Alan Kelly

Journal of Agricultural and Food Chemistry, 2009, 57 (13), pp.5948-5955. ⟨10.1021/jf900518n⟩

Article dans une revue hal-02502915v1
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Proteomic Studies of Saliva: A Proposal for a Standardized Handling of Clinical Samples

François Chevalier , Christophe Hirtz , Sandrine Chay , Frédéric Cuisinier , Nicolas Sommerer et al.

Clinical Proteomics, 2007, 3 (1-4), pp.13 - 21. ⟨10.1007/s12014-007-9000-x⟩

Article dans une revue hal-01743573v1

Salivary protein profiling in type I diabetes using two-dimensional electrophoresis and mass spectrometry

Christophe Hirtz , François Chevalier , Nicolas Sommerer , Isabelle Raingeard , Jacques Bringer et al.

Clinical Proteomics, 2006, 2 (1-2), pp.117-127. ⟨10.1385/CP:2:1:117⟩

Article dans une revue hal-02502403v1

Different Impact of Staining Procedures Using Visible Stains and Fluorescent Dyes for Large-Scale Investigation of Proteomes by MALDI-TOF Mass Spectrometry

François Chevalier , Delphine Centeno , Valerie Rofidal , Marc Tauzin , Olivier Martin et al.

Journal of Proteome Research, 2006, 5 (3), pp.512-520. ⟨10.1021/pr050194n⟩

Article dans une revue hal-02501122v1

MS characterization of multiple forms of alpha-amylase in human saliva

Christophe Hirtz , François Chevalier , Delphine Centeno , Valerie Rofidal , Jean-Christophe Egea et al.

Proteomics, 2005, 5 (17), pp.4597-4607. ⟨10.1002/pmic.200401316⟩

Article dans une revue istex hal-02501106v1

Proteomic investigation of natural variation between Arabidopsis ecotypes

François Chevalier , Olivier Martin , Valerie Rofidal , Anne-Dominique Devauchelle , Samuel Barteau et al.

Proteomics, 2004, 4 (5), pp.1372-1381. ⟨10.1002/pmic.200300750⟩

Article dans une revue istex hal-02501082v1

Proteomic capacity of recent fluorescent dyes for protein staining

François Chevalier , Valerie Rofidal , Pavlina Vanova , Alexis Bergoin , Michel Rossignol

Phytochemistry, 2004, 65 (11), pp.1499-1506. ⟨10.1016/j.phytochem.2004.04.019⟩

Article dans une revue istex hal-02501090v1

Proteomic investigation of natural variation between Arabidopsis ecotypes

François Chevalier , Olivier Martin , Valérie Rofidal , A.D. Devauchelle , S. Barteau et al.

Proteomics, 2004, 4, pp.1372-1381

Article dans une revue hal-02669598v1

Effects of phosphate availability on the root system architecture: large-scale analysis of the natural variation between Arabidopsis accessions

François Chevalier , M. Pata , Philippe Nacry , Patrick Doumas , M. Rossignol

Plant, Cell and Environment, 2003, 26, 12 p. ⟨10.1046/j.1365-3040.2003.01100.x⟩

Article dans une revue hal-01833623v1

Maillard glycation of β-lactoglobulin induces conformation changes

François Chevalier , J.-M. Chobert , M. Dalgalarrondo , Y. Choiset , T. Haertle Article dans une revue istex hal-02501034v1

CHARACTERIZATION OF THE MAILLARD REACTION PRODUCTS OF BETA-LACTOGLOBULIN GLUCOSYLATED IN MILD CONDITIONS

François Chevalier , Jean-Marc Chobert , Michèle Dalgalarrondo , Thomas Haertlé

Journal of Food Biochemistry, 2001, 25 (1), pp.33-55. ⟨10.1111/j.1745-4514.2001.tb00723.x⟩

Article dans une revue istex hal-02500986v1

Scavenging of Free Radicals, Antimicrobial, and Cytotoxic Activities of the Maillard Reaction Products of β-Lactoglobulin Glycated with Several Sugars

François Chevalier , Jean-Marc Chobert , Claude Genot , Thomas Haertlé

Journal of Agricultural and Food Chemistry, 2001, 49 (10), pp.5031-5038. ⟨10.1021/jf010549x⟩

Article dans une revue istex hal-02500999v1

Improvement of functional properties of β-lactoglobulin glycated through the Maillard reaction is related to the nature of the sugar

François Chevalier , Jean-Marc Chobert , Yves Popineau , Marie Georgette Nicolas , Thomas Haertlé

International Dairy Journal, 2001, 11 (3), pp.145-152. ⟨10.1016/S0958-6946(01)00040-1⟩

Article dans une revue istex hal-02501021v1
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Maillard glycation of $\beta$-lactoglobulin with several sugars: comparative study of the properties of the obtained polymers and of the substituted sites

François Chevalier , Jean-Marc Chobert , Daniel Mollé , Thomas Haertlé

Le Lait, 2001, 81 (5), pp.651-666. ⟨10.1051/lait:2001155⟩

Article dans une revue hal-00895361v1

Applications des faisceaux d’ions dans le domaine médical

François Chevalier

École thématique EMIR&A « Interaction des particules chargées avec la matière : Fondements et Applications », EMIR&A, Réseau national d'accélérateurs pour l'irradiation et l'analyse des molécules et matériaux, Feb 2025, Roscoff, France

Communication dans un congrès hal-04941369v1

Dosimetry and cellular mechanisms of carbon ion FLASH irradiations at GANIL

Mateusz Sitarz , Kilian Lecrosnier , Jeevan Babu Amakkattu , Yann Doublet , Jean-Marc Fontbonne et al.

European Nuclear Physics Conference 2025 (EuNPC 2025), Sep 2025, Caen (FR), France

Communication dans un congrès hal-05281268v1

Effet Flash in vitro par irradiation proton à ultra haut débit de dose

Kilian Lecrosnier , Mihaela Temelie , Mihaela Tudor , Mateusz Sitarz , Mihai Radu et al.

4ᵉ édition du Symposium de la recherche scientifique francophone en Europe centrale et orientale "SRSF-ECO’2025", Ambassade de France en Roumanie, en partenariat avec la direction régionale de l’Agence Universitaire de la Francophonie, Oct 2025, Iași, Romania

Communication dans un congrès hal-05353742v1

Conférence plénière inaugurale : Au cœur de l'interaction rayonnement - matière ; Applications des faisceaux d’ions dans le domaine médical

François Chevalier

4ᵉ édition du Symposium de la recherche scientifique francophone en Europe centrale et orientale "SRSF-ECO’2025", Ambassade de France en Roumanie, en partenariat avec la direction régionale de l’Agence Universitaire de la Francophonie, Oct 2025, Iași, Romania

Communication dans un congrès hal-05353730v1

La recherche en hadron biologie pour améliorer le traitement des cancers radio résistants

François Chevalier

Conférence de l'UFR des Sciences de la Santé, Université Iba Der THIAM de Thiès, Oct 2025, Thiès, Senegal

Communication dans un congrès hal-05333632v1

Objectifs du réseau RESPLANDIR et présentation des résultats de l’intercomparaison des plateformes d’irradiation à l’aide de la dosimétrie alanine

Morgane dos Santos , Emilie Bayart , François Chevalier , Charbel Koumeir , Amélia Maia Leite et al.

2ᵉ Congrès RadioTransNet, Nov 2025, Paris, France

Communication dans un congrès hal-05390485v1

Oxygen influence on cell response to 12C-FLASH

Kilian Lecrosnier , Mateusz Sitarz , Jeevan Babu Amakkattu , Yann Doublet , Jean-Marc Fontbonne et al.

FLASH Workshop 2025: The Role of Oxygen in FLASH Radiation Therapy, Jul 2025, Heidelberg (Germany), Germany

Communication dans un congrès hal-05144104v1

Étude multi-protéomique de la réponse précoce aux irradiations par rayons X et ions carbone des cellules HeLa

Ousseynou Bendiouf , Mamadou Soumboundou , Antoine Gilbert , Benoit Bernay , Cheikh Sall et al.

Journées conjointes des départements de Médecine et de Biologie, 2025, Ziguinchor, Sénégal, Senegal

Communication dans un congrès hal-05219012v1

Projet émergent: Irradiation Flash carbone au GANIL

François Chevalier

2ème journée scientifique de la Structure Fédérative Normandie Oncologie, Structure Fédérative 4207, Nov 2024, Caen, France

Communication dans un congrès hal-04804262v1

Projet collaboratif CHOXTRACC : Recherche de combinaisons thérapeutiques hadronthérapie – thérapies ciblant la radiorésistance biologique liée à l’hypoxie et au stress oxydant tumoral

François Chevalier

2ème journée scientifique de la Structure Fédérative Normandie Oncologie, Structure Fédérative 4207, Nov 2024, Caen, France

Communication dans un congrès hal-04804253v1

Effet protecteur du FLASH in vitro en fonction de la lignée cellulaire, de la concentration en oxygène et du TEL des ions carbone

Mateusz Sitarz , Kilian Lecrosnier , Yann Doublet , Jean-Marc Fontbonne , Alain Méry et al.

2ème congrès de radiobiologie de la Société Française de Biologie des Radiations, SFBR, Oct 2024, Porquerolles (Var), France

Communication dans un congrès hal-04756324v1

Role of KRAS mutation on NSCLC resistance to x-rays and carbon ions

Mathieu Césaire , Kilian Lecrosnier , Antoine Gilbert , Juliette Montanari , François Chevalier

JOURNÉES DE L’ÉCOLE DOCTORALE NBISE, May 2024, Caen (FR), France

Communication dans un congrès hal-04684490v1

The majority of DNA repair deficiencies do not alter the correlation between relative biological effectiveness (RBE) and linear energy transfer (LET) in CRISPR-edited cells

Francisco Liberal , Jason Parsons , François Chevalier , Kevin Tabury , Stephen Mcmahon

48th European Radiation Research Society Meeting ERRS 2024, Sep 2024, Aveiro (Portugal), Portugal

Communication dans un congrès hal-04702445v1

Les effets Bystander radio-induits appréhendés à travers l’étude de différents types de radiations

François Chevalier

5ème Séminaire ARCHADE, association ARCHADE, May 2024, Caen (FR), France

Communication dans un congrès hal-04599342v1

Radiobiology at GANIL

François Chevalier

PIANOFORTE WP5 Infrastructure Workshop, INFN, Jan 2024, Catania, Sicily (Italy), Italy

Communication dans un congrès hal-04432820v1

Applications of GANIL Research Activities and Techniques

Fanny Farget , Anne-Marie Frelin , Clara Grygiel , Eloïse Dessay , François Chevalier et al.

AccelApp'24 International Topical Meeting on Nuclear Applications of Accelerators, Mar 2024, Norfolk VA, USA, United States

Communication dans un congrès hal-04513097v1

Initial insights into radiosensitization of Rhabdomyosarcoma for enhanced hadrontherapy outcomes: Progress from the SaRHa Project

Zacharenia Nikitaki , François Chevalier , Siamak Haghdoost

RAD 2024 Conference, Jun 2024, Herceg Novi, Montenegro

Communication dans un congrès hal-04628370v1

Cartilage upon ionizing radiation: from molecular processes to biological effects

Jean-Christophe Poully , François Chevalier , Thomas Schlathölter

DySoN-MultIChem 2024, Apr 2024, Tbilisi, Georgia, Georgia

Communication dans un congrès hal-04553902v1

Activité bystander de matrikines issues de l’irradiation du collagène

Juliette Montanari , Jean Christophe Poully , François Chevalier

2ème congrès de radiobiologie de la Société Française de Biologie des Radiations, SFBR, Oct 2024, Porquerolles (Var), France

Communication dans un congrès hal-04756317v1

Effets de l’hadronthérapie et des inhibiteurs de PARP sur les cellules de chondrosarcome et les chondrocytes

Antoine Gilbert , Kevin Commenchail , Amandine Delaunay , Samuel Valable , François Chevalier

2ème congrès de radiobiologie de la Société Française de Biologie des Radiations, SFBR, Oct 2024, Porquerolles (Var), France

Communication dans un congrès hal-04756328v1

Le sotorasib radiosensibilise le CPNPC muté KRAS G12C in vitro

Kilian Lecrosnier , Mathieu Césaire , Antoine Gilbert , Juliette Montanari , François Chevalier

2ème congrès de radiobiologie de la Société Française de Biologie des Radiations, SFBR, Oct 2024, Porquerolles (Var), France

Communication dans un congrès hal-04756333v1

Etude protéomique et phosphoprotéomique des mécanismes biologiques impliques dans la réponse précoce des cellules HeLa aux irradiations par rayons x et ions carbone

Ousseynou Bendiouf , Mamadou Soumboundou , Antoine Gilbert , Benoit Bernay , Cheikh Sall et al.

Doctorales 2024 / Journées de la Recherche, Université IBA DER THIAM, ED-2DS, Nov 2024, Thiès, Senegal

Communication dans un congrès hal-05219021v1

Radiosensitization of chondrosarcoma cells with PARPi

Antoine Gilbert , François Chevalier

Annual meeting of the DORADIOS project, Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway, Nov 2023, Oslo, Norway

Communication dans un congrès hal-04323153v1

Phospho-proteomic analysis: preliminary results

François Chevalier

Annual meeting of the DORADIOS project, Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway, Nov 2023, Oslo, Norway

Communication dans un congrès hal-04323136v1

Radiation-biology of radioresistant cancer models and bystander effects in a context of hadrontherapy

François Chevalier

General seminar at the Department of Radiation Biology, within the DORADIOS project, Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway, Nov 2023, Oslo, Norway

Communication dans un congrès hal-04320364v1

Plateforme iRiA pour l'accueil des expériences de radiobiologie auprès des faisceaux du GANIL

François Chevalier

Assemblée générale du GDR Mi2B « Outils et méthodes nucléaires pour la lutte contre le cancer », Oct 2023, Bordeaux, France

Communication dans un congrès hal-04268299v1

Radiosensitizing effect of ATM and ATR kinase inhibitors on glioblastoma

Ana-Maria-Adriana Șerban , Mihaela Temelie , Gro Elise Rødland , Antoine Gilbert , François Chevalier et al.

RAP 2023, May 2023, Attica, Greece

Communication dans un congrès hal-05213219v1

La plateforme de Radiobiologie du CIMAP-GANIL

François Chevalier

Journées 2023 du réseau Resplandir "Réseau des Plateformes Nationales d'Irradiation pour la Dosimétrie, l'Instrumentation et la Radiobiologie", Mar 2023, Strasbourg, France

Communication dans un congrès hal-04268316v1

FLASH irradiations with carbon ions: a proof of concept at GANIL

François Chevalier

Annual meeting of the DORADIOS project, Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway, Nov 2023, Oslo, Norway

Communication dans un congrès hal-04323128v1

Programmes de recherche pré-cliniques en cours en proton et ions carbone au CIMAP

François Chevalier

Workshop Radiotransnet : Recherche Préclinique en Protonthérapie & Hadronthérapie, Radiotransnet, Nov 2022, Caen (FR), France

Communication dans un congrès hal-04268409v1

Utilisation d'inhibiteurs KRAS comme agents de radiosensibilisation dans le CBNPC

François Chevalier

Journée Scientifique de l’axe 1 du Cancéropôle Nord-Ouest : Focus sur les cancers du Poumon et du Pancréas, Nov 2022, Paris, France

Communication dans un congrès hal-04268390v1

KRAS inhibitors in combination with X-rays or protons irradiation in NSCLC

Mathieu Césaire , François Chevalier

1er congrés de la SFBR, Nov 2022, Saint Raphael, France

Communication dans un congrès hal-04217173v1

Effets de l’hadronthérapie et des inhibiteurs de PARP sur les cellules souches cancéreuses de chondrosarcome

Antoine Gilbert , François Chevalier

1er congrés de la SFBR, Nov 2022, Saint Raphael, France

Communication dans un congrès hal-04217182v1

Radiosensitization of chondrosarcoma with PARP inhibitors

Antoine Gilbert , François Chevalier

Meeting of the DORADIOS RO-NO EU project, Oct 2022, Bucharest (RO), Romania

Communication dans un congrès hal-04268362v1

Plateforme d’accueil des expériences interdisciplinaires auprès des faisceaux du GANIL

François Chevalier , Jimmy Rangama

Workshop Radiotransnet : Recherche Préclinique en Protonthérapie & Hadronthérapie, Radiotransnet, Nov 2022, Caen (FR), France

Communication dans un congrès hal-04268402v1

Radiation-induced bystander effects in Chondrosarcoma in a context of hadrontherapy: Proteomic approaches

François Chevalier

General seminar of the IFIN-HH institute, Oct 2021, Bucharest (RO), Romania

Communication dans un congrès hal-04268380v1

Charged Particle Irradiation Effects on Human Chondrosarcoma Cells

Mihaela Tudor , François Chevalier , Diana Savu

46th Annual Meeting of the European Radiation Research Society - ERRS 2021, Nov 2021, Caen, France

Communication dans un congrès hal-04674898v1
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Impact of Hypoxia and Hadrontherapy on Radioresistant Chondrosarcoma Cancer Stem Cells

Antoine Gilbert , Julie Laurence , Marilyne Guillamin , Siamak Haghdoost , Samuel Valable et al.

Proceeding of the ERRS 2021, Nov 2021, CAEN, France. pp.93

Communication dans un congrès hal-03757408v1

Radioresistance in Chondrosarcoma using the CIRIL-ARIA biology platform

François Chevalier

22nd COLLOQUE GANIL, Sep 2021, Autrans Meaudre en Vercors, France

Communication dans un congrès hal-04268423v1

Radioresistance and bystander signaling in Chondrosarcoma

François Chevalier

Seminar of the Brancusi PHC project FIDIA2C, Apr 2020, Bucharest (RO), Romania

Communication dans un congrès hal-04268455v1

Direct And Bystander Irradiation Effects Induced By Proton Irradiation Of Chondrosarcoma Cells

Mihaela Tudor , Mihaela Temelie , Liviu Craciun , Cenusa Constantin , François Chevalier et al.

National Online Conference of Biophysics -CNB 2020-, ROMANIAN SOCIETY OF PURE AND APPLIED BIOPHYSICS, Jun 2020, Brasov, Romania

Communication dans un congrès hal-04674870v1

Bystander effects induced by proton irradiated human chondrosarcoma cells

Mihaela Tudor , Mihaela Temelie , Roxana Cristina Popescu , Anna Rzjanina , Gennady Mytsin et al.

Eight international conference on radiation in various fields of research (RAD2020), Jul 2020, Herceg Novi, Montenegro

Communication dans un congrès hal-05213203v1

Low dose irradiation effects on the Normal cells / Tumoral cells dialogue

François Chevalier

Seminar for Brâncusi PHC project "Partenariat Hubert Curien franco-roumain", Nov 2019, Bucharest (RO), Romania

Communication dans un congrès hal-04268478v1

Bystander Effects of human chondrosarcoma cells irradiated with accelerated ions

François Chevalier , Charlotte Lepleux , Aurélie Marie-Brasset , Mihaela Temelie , Marion Boulanger et al.

CNB 2018 - 15th National Conference of Biophysics of the Romanian Society of Pure and Applied Biophysics, Sep 2018, Bucharest (RO), Romania

Communication dans un congrès hal-04236753v1

Multimodal treatments of radio-resistant cancer: emerging effective combined therapy of PARP-1 inhibitors and high-LET particle therapy

Utpal Ghosh , Mihaela Temelie , Diana Savu , François Chevalier

CNB 2018 - 15th National Conference of Biophysics of the Romanian Society of Pure and Applied Biophysics, Sep 2018, Bucharest (RO), Romania

Communication dans un congrès hal-05213193v1

O 086: Radiosensitization Effect of Talazoparib, a PARP inhibitor, on Glioblastoma Stem Cells Exposed to X-rays and Carbon Ions

Y Saintigny , P Lesueur , E El-Habr , MP Junier , H Chneiweiss et al.

57th Annual Meeting of the Particle Therapy Cooperative Group, May 2018, Cincinnati (Ohio, USA), United States

Communication dans un congrès hal-05459808v1

Bystander effect in Hadrontherapy

François Chevalier

Seminar for Sakura PHC project "Partenariat Hubert Curien franco-Japonais", Nov 2017, Tokyo (JP), Japan

Communication dans un congrès hal-04268487v1

Faits et arguments pour une toxicité extra-cellulaire des ions

François Chevalier

CIRFA 13ème Congrès Francophone de Radiobiologie SIRLAF, Dec 2017, Lyon, France

Communication dans un congrès hal-04236724v1

O22: In Vitro Engineering of Human 3D Models of Cartilage and Chondrosarcoma for Hadronbiology

Yannick Saintigny , Dounia Hamdi , François Chevalier , Jean-Louis Lefaix

53rd Annual Meeting for the Particle Therapy Cooperative Group, Jun 2014, Shanghai (Chine), China

Communication dans un congrès hal-05459830v1

De l’intérêt de l’étude approfondie des cartes peptidiques massiques par MALDI-ToF: exemple d’une classe de protéines, les amylases salivaires humaines.

N Sommerer , C Hirtz , François Chevalier , D Centeno , V Rofidal et al.

1er Symposium de Chimie et Biologie Analytiques, Sep 2005, Montpellier, France

Communication dans un congrès hal-04239206v1

Proteomic characterization of arabidopsis ecotypes under phosphate starvation

François Chevalier , O Martin , V Rofidal , N Sommerer , M Rossignol

Third year progress meeting EU-Framework 5 (GVE) Molecular breeding for plant growth and yield, Nov 2004, London (U.K.), United Kingdom

Communication dans un congrès hal-04268593v1

Recherche préliminaire de marqueurs salivaires du diabète de type 1 chez l’homme

C Hirtz , François Chevalier , I Raingeard , Jc Egea , J Bringer et al.

Association Dentaire Française, Nov 2004, Paris, France

Communication dans un congrès hal-04268601v1

Proteomic characterization of arabidopsis ecotypes under phosphate starvation

François Chevalier , A-D Devauchelle , S Barteau , N Sommerer , M Rossignol

Second year progress meeting EU-Framework 5 (GVE) Molecular breeding for plant growth and yield, Oct 2003, Gant, Belgium

Communication dans un congrès hal-04268584v1

Proteomic characterization of arabidopsis ecotypes under phosphate starvation

François Chevalier , P Nacry , M Pata , N Sommerer , M Rossignol

First year progress meeting EU-Framework 5 (GVE) Molecular breeding for plant growth and yield, Nov 2002, Montpellier (FR), France

Communication dans un congrès hal-04268575v1

Radiothérapie FLASH avec des ions carbone: premières études mécanistiques in vitro au GANIL

Mateusz Sitarz , Kilian Lecrosnier , Jeevan Babu Amakkattu , Yann Doublet , Jean-Marc Fontbonne et al.

17 èmes Journées scientifiques annuelles du Cancéropôle Nord-Ouest 2025, May 2025, Deauville, France

Poster de conférence hal-05075954v1

Cellular mechanisms of flash effect with carbon and oxygen ions

Kilian Lecrosnier , Mateusz Sitarz , Yann Doublet , Jean-Marc Fontbonne , Marilyne Guillamin et al.

5th FLASH Radiotherapy and Particle Therapy Conference, Dec 2025, Prague, Czech Republic

Poster de conférence hal-05416169v1

2348 DNA damage response inhibitors enhance interferon signaling in an LET-dependent manner after irradiation of glioblastoma cells

Gro Elise Rødland , Mihaela Temelie , Adrian Eek Mariampillai , Ana Maria Serban , Nina Frederike J. Edin et al.

ESTRO 2025, May 2025, Vienna, Austria. 206, pp.S3878-S3879, 2025, ⟨10.1016/S0167-8140(25)00992-2⟩

Poster de conférence hal-05125951v1

In vitro flash effect as a function of ultra-high dose rates with proton beam

Mihaela Temelie , Mateusz Sitarz , Mihaela Tudor , Kilian Lecrosnier , Mihai Radu et al.

PTCOG 63, Jun 2025, Buenos AIres, Argentina

Poster de conférence hal-05118358v1

Le sotorasib radiosensibilise le cancer bronchique muté KRAS G12C in vitro

Mathieu Cesaire , Kilian Lecrosnier , Juliette Montanari , Serge Candéias , François Chevalier

17 èmes Journées scientifiques annuelles du Cancéropôle Nord-Ouest 2025, May 2025, Deauville, France

Poster de conférence hal-05076003v1

Dosimetric System for Flash in vitro Studies with Passively Scattered Carbon Beam at GANIL

Marc Rousseau , Mateusz Sitarz , Yann Doublet , Jean-Marc Fontbonne , Simon Lechien et al.

FRPT 2024, Dec 2024, Roma, Italy

Poster de conférence hal-04828024v1

Investigation of Flash Effect in vitro using Healthy and Tumor Cells with Carbon Ions at GANIL

Mateusz Sitarz , Kilian Lecrosnier , Yann Doublet , Jean-Marc Fontbonne , Alain Méry et al.

FRPT 2024, Dec 2024, Roma, Italy

Poster de conférence hal-04828016v1

Role of KRAS mutation on NSCLC resistance to x-rays and carbon ions

Kilian Lecrosnier , Mathieu Césaire , Antoine Gilbert , Juliette Montanari , François Chevalier

Journée Normande de Recherche Biomédicale, Jun 2024, Rouen (France), France.

Poster de conférence hal-04614592v1

Phospho-proteomics analysis of early-response to x-ray irradiation reveals molecular mechanisms potentially related to U251 cells radioresistance

Ousseynou Ben Diouf , Antoine Gilbert , Benoit Bernay , Mamadou Soumboundou , Radhia M’kacher et al.

Journée Normande de Recherche Biomédicale, Jun 2024, Rouen (France), France.

Poster de conférence hal-04614598v1

Radiosensitizing effects of PARP inhibition on chondrosarcoma cells and chondrocytes according to radiation LET

Antoine Gilbert , Raphael Leman , Samuel Valable , François Chevalier

Journées de l'EDnBISE 2024, May 2024, Caen (FR), France

Poster de conférence hal-04684479v1

Radiobiology platform for carbon Flash research at GANIL

François Chevalier , Mateusz Sitarz , Kilian Lecrosnier , Yann Doublet , Simon Lechien et al.

FRPT 2024, Dec 2024, Roma, Italy

Poster de conférence hal-04827993v1
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Monte Carlo Modelization and Dosimetric Verification of C beamline components for Radiobiological studies

Jeevan Babu Amakkattu , Mateusz Sitarz , Violaine Vizcaino , François Chevalier , Alain Méry

Joliot-Curie School - Radiations for Health, Sep 2024, St Pierre d'Oléron, France.

Poster de conférence hal-04705560v1

Radiosensitizing effects of PARP inhibition on chondrosarcoma cells and chondrocytes according to radiation LET

Antoine Gilbert , Raphaël Leman , Samuel Valable , François Chevalier

Journée Normande de Recherche Biomédicale, Jun 2024, Rouen (France), France.

Poster de conférence hal-04614581v1

IFN signaling after proton and carbon ion irradiation is enhanced by ATR inhibition

Gro Elise Rødland , Mihaela Temelie , Ana-Maria Șerban , Adrian Eek Mariampillai , Nina Frederike Jeppesen Edin et al.

NIRO Annual Meeting 2023, Sep 2023, Jessheim, Norway

Poster de conférence hal-04217154v1

IFN signaling after proton and carbon ion irradiation is enhanced by inhibitors of ATR but not ATM kinase

Gro Elise Rødland , Mihaela Temelie , Ana-Maria Șerban , Nina Frederike Jeppesen Edin , Eirik Malinen et al.

International Wolfsberg Meeting on Molecular Radiation Biology/Oncology, Jun 2023, Oslo, Norway

Poster de conférence hal-04217066v1

Hadrontherapy and PARP inhibitors effects on chondrosarcoma cancer stem cells

Antoine Gilbert , Kevin Commenchail , Samuel Valable , François Chevalier

ICRR 2023, Aug 2023, Montréal Québec, Canada

Poster de conférence hal-04217091v1

Atr kinase inhibitor augments ifn signaling following proton and carbon ion irradiation

Diana Iulia. Savu , Gro Elise Rødland , Mihaela Temelie , Ana-Maria Serban , Adrian E. Mariampillai et al.

ICRR 2023, Aug 2023, Montréal Québec, Canada

Poster de conférence hal-04217114v1
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Bystander communication between irradiated chondrosarcoma cells and non-irradiated chondrocytes: proteomic study according to doses and LETs

A Gilbert , M Tudor , D Savu , S Candéias , François Chevalier

ICRR2023 - the 17th International Congress for Radiation Research, Aug 2023, Montréal, Canada.

Poster de conférence hal-04217083v1

Glioblastoma and glioblastoma stem-like cancer cells radiosensitization to X-ray and carbon ions using ATM and ATR inhibitors

Mihaela Temelie , Mihaela Tudor , Ana-Maria Serban , Gro Elise Rødland , Daniela Stroe et al.

ICRR 2023, Aug 2023, Montréal (Quebec), Canada

Poster de conférence hal-04217139v1

Investigation of proton irradiation induced effects in chondrosarcoma and bystander normal chondrocytes and endothelial cells

Tudor M. , Temelie M. , Gilbert A. , Dinischiotu A. , François Chevalier et al.

RAP2023, May 2023, Attica, Greece

Poster de conférence hal-04217042v1
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Role of KRAS mutation on NSCLC resistance to X-rays and protons

Juliette Montanari , Mathieu Césaire , Antoine Gilbert , François Chevalier

ERRS 2022 - 47th Annual Meeting of the European Radiation Research Society, Sep 2022, Catania, Italy.

Poster de conférence hal-03808183v1
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Impact de l'hadronthérapie par ions carbone et protons sur les cellules souches cancéreuses de chondrosarcome en hypoxie

Antoine Gilbert , Juliette Montanari , Kévin Commenchail , Marilyne Guillamin , Samuel Valable et al.

14éme journée scientifique de la cancéropôle Nord-Ouest, May 2022, Deauville, France

Poster de conférence hal-03757233v1
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Analysis of ionizing radiation induced effects in radioresistant tumours and bystander normal cells

M Tudor , A Gilbert , M Temelie , A Dinischiotu , François Chevalier et al.

46th FEBS Congress, Jul 2022, Lisbon, Portugal

Poster de conférence hal-03757272v1

Direct and bystander effects of human chondrosarcoma cell line irradiated with protons

Mihaela Tudor , Roxana Popescu , Mihaela Temelie , François Chevalier , Diana Savu

Ninth International Conference on Radiation in Various Fields of Research -RAD 2021 Conference, Jun 2021, Herceg Novi, Montenegro.

Poster de conférence hal-04674892v1
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Sensitization of chondrosarcoma cells with PARP inhibitor and impact on cancer stem cells

Mathieu Césaire , Antoine Gilbert , Julie Laurence , Nicolas Elie , Florence Giffard et al.

ERRS 2021, Nov 2021, CAEN, France

Poster de conférence hal-03757108v1
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Presentation of the CIRIL / radiation biology platform dedicated for experiments with the GANIL facility

Chevalier François , Violaine Vizcaino , Jean-Christophe Poully , Alain Mery , Jimmy Rangama

ERRS 2021, Nov 2021, CAEN, France

Poster de conférence hal-03757189v1
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Proteomic analysis of bystander effects in chondrosarcoma cells

Antoine Gilbert , Mihaela Tudor , Charlotte Lepleux , Valérie Rofidal , Sonia Hem et al.

45th Annual Meeting of the European Radiation Research Society, Sep 2020, Lund, Sweden. , pp.123

Poster de conférence hal-03144446v1

Bystander effects induced by proton-irradiated human chondrosarcoma cells

Mihaela Tudor , Mihaela Temelie , Roxana Cristina Popescu , Anna Rzjanina , Gennady Mytsin et al.

Eighth International Conference on Radiation in Various Fields of Research - RAD 2020 virtual Conference, Jun 2020, Herceg Novi, Montenegro.

Poster de conférence hal-04674882v1

Radiosensitization effects of doxorubicin-iron oxide nanosystem in charged particle radiation-therapy for human chondrosarcoma

Mihaela Tudor , Roxana Popescu , Anna Rzjanina , Gennady Mytsin , Mihai Radu et al.

Eighth International Conference on Radiation in Various Fields of Research - RAD 2020 virtual Conference, Jun 2020, Herceg Novi, Montenegro.

Poster de conférence hal-04674886v1
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Bystander effectors of chondrosarcoma cells irradiated at different LET impair proliferation of chondrocytes

Charlotte Lepleux , Aurélie Marie-Brasset , Emilie Brotin , Tetsuo Nakajima , Diana Savu et al.

ENLIGHT Annual Meeting and Training 2019, Jul 2019, Caen, France

Poster de conférence hal-03144584v1
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Sensitization of chondrosarcoma cells with PARP inhibitor and high-LET radiation

Mathieu Césaire , Utpal Ghosh , Jean Baptiste Austry , Francesco Cammarata , Laurent Castera et al.

ENLIGHT Annual Meeting and Training 2019, Jul 2019, Caen, France

Poster de conférence hal-03144597v1
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Proteomic analysis of the Radiation-Induced Bystander Effects

Charlotte Lepleux , François Chevalier

ENLIGHT Annual Meeting and Training 2019, Jul 2019, Caen, France

Poster de conférence hal-03144600v1
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P23 - Bystander effectors of chondrosarcoma cells irradiated at different LET impair proliferation of chondrocytes

Charlotte Lepleux , Diana Savu , François Chevalier

16th International Congress of Radiation Research, Aug 2019, Manchester, United Kingdom

Poster de conférence hal-03144483v1
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P47. Proteomic analysis of the Radiation-Induced Bystander Effects between low-dose irradiated Chondrosarcoma cells and Bystander Chondrocytes

Charlotte Lepleux , Valerie Rofidal , Sonia Hem , Christine Almunia , J. Armengaud et al.

4th European Radiation Protection Week, Oct 2019, Stockholm, Sweden

Poster de conférence hal-03144468v1
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High LET Radiation Overcomes in vitro Resistance to X-rays of Chondrosarcoma Cell Lines

Dounia Houria Hamdi , Charlotte Lepleux , Agnès Nicolle , Guillaume Varès , Paul Lesueur et al.

ENLIGHT Annual Meeting and Training 2019, Jul 2019, Caen, France

Poster de conférence hal-03144579v1

P 014: Study of Bystander Effects in Chondrosarcoma Cells Irradiated In Vitro with X-Rays and Carbon Ions

François Chevalier , Charlotte Lepleux , Aurélie Marie-Brasset , Yannik Saintigny

57th Annual Meeting of the Particle Therapy Cooperative Group, May 2018, Cincinnati (Ohio, USA), United States

Poster de conférence hal-05459796v1

P 010 - Radio-sensitization of Chondrosarcoma Cells by PARP-inhibitors

François Chevalier , Mathieu Césaire , Yannik Saintigny

57th Annual Meeting of the Particle Therapy Cooperative Group, May 2018, Cincinnati (Ohio, USA), United States

Poster de conférence hal-05459813v1
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Discriminating sub-population responses of a mixture of human cell lines by proteogenomics

Christine Almunia , Yannick Cogne , Olivier Pible , Charlotte Lepleux , François Chevalier et al.

43rd FEBS Congress, Biochemistry Forever, Prague, Czech Republic, July 7-12, 2018, Jul 2018, Prague (CZ), France

Poster de conférence hal-04475761v1
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Study of bystander signals emitted by chondrosarcoma cells irradiated in vitro with X-rays and carbon ions

François Chevalier , Charlotte Lepleux

ERRS and GBS 2017 - the Joint 43rd European Radiation Research Society (ERRS) and 20th German Society for Biological Radiation Research (GBS) Annual Meetings, Sep 2017, Essen, Germany.

Poster de conférence hal-04236739v1
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Radio-sensitization of chondrosarcoma cells by PARP inhibitors

Utpal Ghosh , Jean-Baptiste Austry , Francesco Paulo Cammarata , Renata Leanza , Pietro Pisciotta et al.

ERRS and GBS 2017 - the Joint 43rd European Radiation Research Society (ERRS) and 20th German Society for Biological Radiation Research (GBS) Annual Meetings", Sep 2017, Essen, Germany

Poster de conférence hal-04236732v1
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Méta-analyses protéogénomiques d’un effet Bystander radio-induit aux faibles doses

Charlotte Lepleux , Christine Almunia , Olivier Pible , Diana Tronic-Le Roux , Jean Armengaud et al.

Congrès SFEAP 2016 - Congrès de la Société Française d'Electrophorèse et d’Analyse Protéomique, Oct 2016, Chambéry, France.

Poster de conférence hal-04236701v1
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Proliferation impairment of chondrosarcoma cells irradiated with X-Rays and carbon-ion beams

François Chevalier , Dounia Houria Hamdi , Yvonne De Jong , Judith V. M. G.. Bovée , Yannick Saintigny

PTCOG55 2016 - the 55th Annual Meeting for the Particle Therapy Cooperative Group, May 2016, Prague, Czech Republic.

Poster de conférence hal-04236718v1

P047: In vitro Engineering of Human 3D Chondrosarcoma: a Preclinical Model Relevant to Hadrontherapy

Yannick Saintigny , Dounia Hamdi , François Chevalier , Yvonne de Jong , Judith Bovee et al.

53rd Annual Meeting for the Particle Therapy Cooperative Group, Jun 2014, Shanghai (Chine), China

Poster de conférence hal-05459846v1
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P046: Engineering of a 3D cartilage model: study of healthy cartilage exposition during hadrontherapy

François Chevalier , Dounia Hamdi , Yannick Saintigny , Florence Legendre , Magali Demoor et al.

PTCOG 53 - Particle Therapy Co-Operative Group, Jun 2014, Shanghai, China.

Poster de conférence hal-04235720v1
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Analysis of targeted effects of ionizing radiations on reconstructed human healthy cartilage and chondrosarcoma

Dounia H. Hamdi , François Chevalier , Jean-Emmanuel Groetz , Jl Lefaix , Yannick Saintigny

60th annual meeting of the Radiation Research Society, Sep 2014, Las Vegas, United States.

Poster de conférence hal-04248682v1

In vitro engineering of human cartilage: a preclinical model relevant to exposition of surrounding healthy tissues during radiotherapy

François Chevalier , Dounia Hamdi , Jean-Louis Lefaix

Workshop on 3D culture models for radiation and cancer research, Sep 2013, Rotterdam (NL), Netherlands

Poster de conférence hal-04235688v1
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Proteomic comparison of ALT and Telomerase+ Glioma Stem cells

François Chevalier , David Silvestre , Maya Jeitany , Jordane Depagne , Pascale Bertrand et al.

HUPO 2011 10th World Congress, Sep 2011, Genève, Switzerland.

Poster de conférence hal-04244543v1

Analysis of proteins in the secretome of the mouse developing testis

François Chevalier , Marie-Justine Guerquin , Jordane Depagne , Pascale Bertrand , René Habert et al.

5ème rencontre Plasticité et Instabilité des Génomes PIG-5, Nov 2009, Marcoule, France

Poster de conférence hal-04484368v1
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Analysis of proteins in the secretome of the mouse developing testis

François Chevalier , Marie-Justine Guerquin , Jordane Depagne , Pascale Bertrand , René Habert et al.

SMAP 2009 - Congrès Français de Spectrométrie de Masse et d’Analyse Protéomique, Sep 2009, Dijon, France

Poster de conférence hal-04244517v1
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Proteins and proteolysis in pre-term and term human milk samples

François Chevalier , Emanuele Armaforte , A Ryan , Al Kelly

The 38th UCC Annual Research Conference hosts on Food, Nutrition and Consumer Sciences, Sep 2008, Cork, Ireland

Poster de conférence hal-04244470v1
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Study of protein complex formation during storage and gelation of UHT milk

E Armaforte , François Chevalier , M. F. Caboni , M. A. E. Auty , A. L. Kelly

The 38th UCC Annual Research Conference hosts on Food, Nutrition and Consumer Sciences, Sep 2008, Cork, Ireland

Poster de conférence hal-04244482v1
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Research of diffusible factors secreted during radio-induced mammary tumor cell death

François Chevalier , Jordane Depagne , Sylvie Chevillard , Pascale Bertrand , Jérôme Lebeau

25ème congrès de la SFEAP, Oct 2008, Tour, France

Poster de conférence hal-04244503v1
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Proteomic changes in milk after heat treatment

François Chevalier , Katharina Hinz , Alan L. Kelly

The IDF World Dairy Summit, Sep 2007, Dublin, Ireland.

Poster de conférence hal-04244453v1

Proteomic study of changes in milk protein profile with increasing somatic cell count

K Hinz , François Chevalier , B Larsen L , M Bruckmaier R , L Kelly A

International Dairy Federation: World Dairy Summit 2007, Sep 2007, Dublin, Ireland

Poster de conférence hal-04244443v1
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Cytokin in action is linked to oxidative stress as shown by proteome analysis in $Arabidopsis$

P Vanova , François Chevalier , V Rofidal , M Rossignol , J Malbeck et al.

19th annual meeting of the International Plant growth substance Association, Jul 2007, Puerto Vallarta, Mexico

Poster de conférence hal-04239178v1
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Proteomic comparison of human milk from term and pre-term mothers

François Chevalier , Emanuele Armaforte , Erika Curran , C. Antony Ryan , Alan L. Kelly

International Dairy Federation: World Dairy Summit 2007, Sep 2007, Dublin, Ireland

Poster de conférence hal-04244460v1

Salivary protein profiling in type 1 diabetes using proteomic tools

C Hirtz , François Chevalier , N. Sommerer , I Raingeard , J Bringer et al.

IADR Pan European Federation 2006, Sep 2006, Dublin (Ireland), Ireland

Poster de conférence hal-04239185v1
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Unexpected proteomics and biochemical complexity of human salivary $\alpha$-amylases in 2D gels

Nicolas Sommerer , Christophe Hirtz , Jean-Pascal Gimeno , François Chevalier , Delphine Centeno et al.

17th International Mass Spectrometry Conference, Aug 2006, Prague, Czech Republic.

Poster de conférence hal-04239153v1
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Link between cytokinins, oxidative stress and jasmonic acid as revealed by proteome analysis in $Arabidopsis$

P Vanova , François Chevalier , V Rofidal , M Rossignol , J Malbeck et al.

XV FESPB Congress - Federation of European Societies of Plant Biology, Jul 2006, Lyon, France.

Poster de conférence hal-04239138v1
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Human saliva proteome reveal unexpected forms of alpha-amylase.

C. Hirtz , François Chevalier , D. Centeno , V. Rofidal , J. C. Egea et al.

Joint Meeting of the Continental European (CED) and the Scandinavian (NOF) Divisions of IADR, Sep 2005, Amsterdam (Hollande), Netherlands

Poster de conférence hal-04239129v1

Scavenging of free radicals, anti-microbial and cytotoxic activities of the maillard reaction products of ß-lactoglobulin glycated with various sugars

François Chevalier , Jean-Marc Chobert , Claude Genot , Thomas Haertlé

Thermally processed food : possible health implications Working Groups & Management Committee Meetings, Apr 2005, Larnaca, Cyprus

Poster de conférence hal-04239193v1
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Effects of elevated endogenous cytokinin levels on the $Arabidopsis\ thaliana$ proteome

Pavlina Vanova , François Chevalier , Valérie Rofidal , Michel Rossignol , Jiri Malbeck et al.

ACPD 2005 - Auxins And Cytokinins In Plant Development International symposium, Jul 2005, Prague, Czech Republic.

Poster de conférence hal-04239116v1
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Modulation de l’expression de protéines salivaires lors du diabète de type 1

Christophe Hirtz , François Chevalier , Sandrine Chay , Isabelle Raingeard , Jacques Bringer et al.

1er Symposium de Chimie et Biologie Analytiques, Sep 2005, Montpellier, France

Poster de conférence hal-04239199v1
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Identification des protéines par MALDI-TOF après électrophorèse 2D : Performance et compatibilité comparaison du bleu colloïdal (CCB), nitrate d'argent (SN), Spyro$^{TM}$ Ruby (SR) and Deep Purple$^{TM}$ (DP)

Nicolas Sommerer , François Chevalier , Valérie Rofidal , Delphine Centeno , Marc Tauzin et al.

1er Symposium de Chimie et Biologie Analytiques, Sep 2005, Montpellier, France

Poster de conférence hal-04239209v1
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Comparative proteomics to reveal naturally occurring variability in Arabidopsis thaliana accessions.

François Chevalier , Anne-Dominique Devauchelle , Samuel Barteau , Olivier Martin , Nicolas Sommerer et al.

Proteomic Forum München, Sep 2003, Munich, Germany

Poster de conférence hal-04239084v1
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Glycation leads to polymerization and tryptic resistance of beta-lactoglobulin

François Chevalier , Jean-Marc Chobert , Thomas Haertle

Milk protein conference, Mar 2000, Vinstra, Norway

Poster de conférence hal-04239052v1
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Effects of Ionizing Radiation in Cancer Radiotherapy

François Chevalier

François Chevalier. MDPI, 2025, 978-3-7258-3386-3

Ouvrages (ouvrage de synthèse) hal-05096820v1
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Radiobiology of Combining Radiotherapy with Other Cancer Treatment Modalities

Vidhula Ahire , Niloefar Ahmadi Bidakhvidi , Tom Boterberg , Pankaj Chaudhary , François Chevalier et al.

Radiobiology Textbook, Springer International Publishing, pp.311 - 386, 2023, ⟨10.1007/978-3-031-18810-7_6⟩

Chapitre d'ouvrage hal-04221267v1
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Basic Concepts of Radiation Biology

Ans Baeyens , Ana Margarida Abrantes , Vidhula Ahire , Elizabeth Ainsbury , Sarah Baatout et al.

Radiobiology Textbook, Springer International Publishing, pp.25-81, 2023, ⟨10.1007/978-3-031-18810-7_2⟩

Chapitre d'ouvrage hal-04221255v1

Identification of factors involved in neurogenesis recovery following irradiation of the adult mouse subventricular zone, a preliminary study

François Chevalier , A Chicheportiche , M Daynac , J Depagne , P Bertrand et al.

Tsz-Kwong Man and Ricardo J. Flores. Proteomics – Human Diseases and Protein Functions, InTech, pp.327-346, 2012, 978-953-307-832-8

Chapitre d'ouvrage hal-04239262v1

Analytical Methods / Mass Spectrometric Methods

François Chevalier , Nicolas Sommerer

Encyclopedia of Dairy Sciences, Academic Press, 2011, 978-0-12-374407-4. ⟨10.1016/B978-0-12-374407-4.00019-4⟩

Chapitre d'ouvrage hal-02805378v1

Milk Proteins : Proteomics

François Chevalier

McSweeney PLH. Encyclopedia of Dairy Sciences, Second Edition, vol. 1, Academic Press, pp.843-847, 2011

Chapitre d'ouvrage hal-04239251v1

What future for “Gel-based proteomic” approaches?

François Chevalier

Giselle C. Rancourt. Proteomics: Methods, Applications and Limitations, Protein Biochemistry, Synthesis, Structure and Cellular Functions, Nova Science Publishers, pp.31-52, 2011, 978-1-61668-691-8

Chapitre d'ouvrage hal-04239235v1

Analytical Methods: Electrophoresis

François Chevalier

McSweeney PLH. Encyclopedia of Dairy Sciences, Second Edition, vol. 1, Academic Press, pp.185-192, 2011

Chapitre d'ouvrage hal-04239245v1

Visible and Fluorescent Staining of Two-Dimensional Gels

François Chevalier , Valerie Rofidal , Michel Rossignol

Plant Proteomics, 355, Humana Press, pp.145-156, 2007, ⟨10.1385/1-59745-227-0:145⟩

Chapitre d'ouvrage hal-02501127v1

Interfacial properties of glycated ß-lactoglobulin

François Chevalier , J-M Chobert , T Haertlé

Marc Anton. Recent Advances in Agricultural and Food Chemistry, Research Signpost, pp.117-125, 2002, 81-7736-102-3

Chapitre d'ouvrage hal-04239224v1