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Francois PUEL

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Dr. François PUEL Professor, ###### Head, Process Engineering and Materials Research Department (LGPM) ##### CentraleSupélec, Université Paris-Saclay, France **Skills**: Mass transfer, Crystallization, Filtration, Emulsification, Process scale-up and industrialization, modelling of particulate processes; Experimental investigation, Solid state transition, Process Analytical Technologies (PATs) **Domains of application:** crystallization and formulation of powders; purification of ingredients (chemicals, pharmaceutics, cosmetics) and industrial products, bio-processes **Leadership:** Head of a 70-people Lab , Participation to national and international networks namely in the field of industrial crystallization. Expert for French, Swiss and Belgian research agencies, Expertise and executive training for industry. <a name="_Toc284084912"></a>Resume ---------------------------------- A graduate of the Chemical Engineering School of Lyon, he received his PhD in Chemical Engineering from the University of Lyon1 (UL1) in 1994. Then he joined the solid processing department at Rhône-Poulenc Research &amp; Development Lab. in Decines, France for 8 years. He was engaged in the development of crystallization processes from laboratory to industrial scale as a senior scientist. He received the senior Moulton Medal in 1997 since he transferred a modelling framework from academy to industry. He joined UL1 in 2001 as an associate professor. He achieved in 2014 full professorship at the renowned Ecole Centrale Paris (now CentraleSupélec since January 2015). His major challenge is to develop an expertise in chemical engineering and industrial biotechnology at CentraleSupélec both in teaching and research. In 2015, he was appointed head of the Biochemical &amp; Chemical Engineering Education Department. In 2020 he took over the head of the LGPM research department in 2020. He cumulates a total of 59 papers in peer-review journals (WoS), 3 book chapters (international ed.), 4 patents and more than 110 contributions (oral and poster) at scientific conferences, including 5 keynotes (ORCID : <http://orcid.org/0000-0001-6059-7273>). 0n 4th of March 2022: 1753 citations and h-factor = 25 (WoS – citation metrics at <https://publons.com/researcher/1432087/francois-puel/metrics/>) 2755 citations and h-factor = 30 (Google scholar metrics at https://scholar.google.fr/citations?user=dJSnW8gAAAAJ&amp;hl=fr/) ; Full list of publications : <https://cv.archives-ouvertes.fr/francois-puel>
Dr. François PUEL (2022/11/07) Professor, Head, Process Engineering and Materials Research Department (LGPM) CentraleSupélec, Université Paris-Saclay, France **Skills**: Mass transfer, Crystallization, Filtration, Emulsification, Process scale-up and industrialization, modelling of particulate processes; Experimental investigation, Solid state transition, Process Analytical Technologies (PATs) **Domains of application:** crystallization and formulation of powders; purification of ingredients (pharmaceutics, cosmetics) and industrial products (nuclear fuel, crop science), bio-processes **Leadership:** Head of a 60-people research department, Participation to national and international networks namely in the field of crystallization. Expert for French, Swiss and Belgian research agencies, Expertise and executive training for industry. <a name="_Toc284084912"></a>Resume ---------------------------------- A graduate of the Chemical Engineering School of Lyon, he received his PhD in Chemical Engineering from the University of Lyon1 (UL1) in 1994. Then he joined the solid processing department at Rhône-Poulenc Research &amp; Development Lab. in Decines, France for 8 years. He was engaged in the development of crystallization processes from laboratory to industrial scale as a senior scientist. He received the senior Moulton Medal in 1997 since he transferred a modelling framework from academy to industry. He joined UL1 in 2001 as an associate professor. He achieved in 2014 full professorship at the renowned Ecole Centrale Paris (now CentraleSupélec since January 2015). His major challenge is to develop an expertise in life science and biotechnologies at Ecole Centrale Paris both in teaching and research. He was appointed head of the BioProcess &amp; Chemical Engineering Education Department in 2015 and head of the Chemical Engineering and Materials Research Department (LGPM EA4038) in 2020. He cumulates a total of 59 papers in peer-review journals (WoS), 3 book chapters (international ed.), 4 patents and more than 110 contributions (oral and poster) at scientific conferences, including 5 keynotes (ORCID :<http://orcid.org/0000-0001-6059-7273> ). 0n 7th of November 2022: 1,836 citations and h-factor = 25 (WoS – citation metrics at <https://publons.com/researcher/1432087/francois-puel/>) 2,891 citations and h-factor = 30 (Google scholar metrics at [https://scholar.google.fr/citations?user=dJSnW8gAAAAJ&amp;hl=fr/](https://scholar.google.fr/citations?user=dJSnW8gAAAAJ&hl=fr/)) . Full list of publications : <https://cv.archives-ouvertes.fr/francois-puel>

Publications

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Flowability characterization of torrefied biomass powders: static and dynamic testing

John Pachón-Morales , Julien Colin , Joel Casalinho , Patrick Perre , François Puel et al.
Biomass and Bioenergy, 2020, 138, pp.105608. ⟨10.1016/j.biombioe.2020.105608⟩
Journal articles hal-02903554v1
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Potential of DEM for investigation of non- consolidated flow of cohesive and elongated biomass particles

John Pachón-Morales , Patrick Perré , Joel Casalinho , Huy Do , Dingena Schott et al.
Advanced Powder Technology, 2020, 31 (4), pp.1500-1515. ⟨10.1016/j.apt.2020.01.023⟩
Journal articles hal-02936438v1

Shear stress computation in a millimeter thin flat panel photobioreactor: Numerical design validated by experiments

Wenbiao Jiang , Wendie Levasseur , Joel Casalinho , Thierry Martin , François Puel et al.
Biotechnology and Applied Biochemistry, 2020, ⟨10.1002/bab.1894⟩
Journal articles hal-03046741v1
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Biomethane production by adsorption technology: New cycle development, adsorbent selection and process optimization

Najib Chouikhi , Federico Brandani , Pluton Pullumbi , Patrick Perré , François Puel et al.
Adsorption - Journal of the International Adsorption Society, 2020, pp.21-24. ⟨10.1007/s10450-020-00250-3⟩
Journal articles hal-02936480v1
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DEM modelling for flow of cohesive lignocellulosic biomass powders: Model calibration using bulk tests

John Pachón-Morales , Huy Do , Julien Colin , François Puel , Patrick Perre et al.
Advanced Powder Technology, 2019, 30 (4), pp.732-750. ⟨10.1016/j.apt.2019.01.003⟩
Journal articles hal-02294258v1
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Effect of torrefaction intensity on the flow properties of lignocellulosic biomass powders

John Pachón-Morales , Julien Colin , Floran Pierre , François Puel , Patrick Perre et al.
Biomass and Bioenergy, 2019, 120, pp.301-312. ⟨10.1016/j.biombioe.2018.11.017⟩
Journal articles hal-01959291v1
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Influence of micromixing time and shear rate in fast contacting mixers on the precipitation of boehmite and NH 4 -dawsonite

Robin Lafficher , Mathieu Digne , Fabien Salvatori , Malika Boualleg , Didier Colson et al.
Chemical Engineering Science, 2018, 175, pp.343-353. ⟨10.1016/j.ces.2017.10.011⟩
Journal articles hal-01654484v1
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Drop size distribution monitoring of oil-in-water emulsions in SMX+ static mixers: Effect of operating and geometrical conditions

Elodie Chabanon , Nida Sheibat-Othman , O. Mdere , Jean-Pierre Valour , Sébastien Urbaniak et al.
International Journal of Multiphase Flow, 2017, 92, pp.61 - 69. ⟨10.1016/j.ijmultiphaseflow.2017.03.001⟩
Journal articles hal-01507424v1
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Development of new alumina precipitation routes for catalysis applications

Robin Lafficher , Mathieu Digne , Fabien Salvatori , Malika Boualleg , Didier Colson et al.
Journal of Crystal Growth, 2017, 468, pp.526-530. ⟨10.1016/j.jcrysgro.2016.11.092⟩
Journal articles hal-01534077v1
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Flowability of lignocellulosic biomass powders: influence of torrefaction intensity

John Pachón-Morales , Julien Colin , Floran Pierre , Thibaut Champavert , François Puel et al.
EPJ Web of Conferences, 2017, Powders and Grains 2017 – 8th International Conference on Micromechanics on Granular Media, 140, pp.4. ⟨10.1051/epjconf/201714013017⟩
Journal articles hal-01656548v2
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Ammonium aluminium carbonate hydroxide NH 4 Al(OH) 2 CO 3 as an alternative route for alumina preparation: Comparison with the classical boehmite precursor

Robin Lafficher , Mathieu Digne , Fabien Salvatori , Malika Boualleg , Didier Colson et al.
Powder Technology, 2017, 320, pp.565 - 573. ⟨10.1016/j.powtec.2017.07.080⟩
Journal articles hal-01654472v1
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Processing-induced-transformations (PITs) during direct compression: impact of compression speeds on phase transition of caffeine

Audrey Juban , Stephanie Briancon , François Puel
Drug Development and Industrial Pharmacy, 2016, 42 (11), pp.1857 - 1864. ⟨10.1080/03639045.2016.1179753⟩
Journal articles hal-01398336v1
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Influence of particle size and shape properties on cake resistance and compressibility during pressure filtration

D. Bourcier , J.P. Féraud , D. Colson , K. Mandrick , D. Ode et al.
Chemical Engineering Science, 2016, 144, pp.176-187. ⟨10.1016/j.ces.2016.01.023⟩
Journal articles hal-01279589v1
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On droplets size distribution in a pulsed column. Part I: In-situ measurements and corresponding CFD–PBE simulations

A. Amokrane , S. Maass , F. Lamadie , François Puel , S. Charton et al.
Chemical Engineering Journal, 2016, 296, pp.366-376. ⟨10.1016/j.cej.2016.03.089⟩
Journal articles hal-01301432v1
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Processing-induced-transformations (PITs) during direct compression: Impact of tablet composition and compression load on phase transition of caffeine

Audrey Juban , Stéphanie Briançon , François Puel
International Journal of Pharmaceutics, 2016, 501 (1-2), pp.253-264. ⟨10.1016/j.ijpharm.2016.01.079⟩
Journal articles hal-01279575v1
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Filtration Process Optimization: Rheological Behavior of a Filter Cake at Different Moisture Contents

Damien Bourcier , Yan Siong Kong , Jean-Pierre Feraud , Denis Ode , Didier Colson et al.
Chemical Engineering and Technology, 2016, Mechanical Particle-fluid Separation Technology, 39 (3), pp.515-521. ⟨10.1002/ceat.201500426⟩
Journal articles hal-01279592v1

Formulation des systèmes pâteux ou préparations semi-solides

Marie-Alexandrine Bolzinger , Stephanie Briançon , Y. Chevalier , François Puel
Techniques de l'Ingenieur, 2015, PHA2016
Journal articles hal-01273308v1

Formation of microcapsules by complex coacervation

Delphine Ach , Stéphanie Briançon , Guy Broze , François Puel , Alain Rivoire et al.
Canadian Journal of Chemical Engineering, 2015, 93 (2 (SI)), pp. 183-191. ⟨10.1002/cjce.22086⟩
Journal articles hal-01273155v1
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Predictive model for tensile strength of pharmaceutical tablets based on local hardness measurements

Audrey Juban , Cécile Nouguier-Lehon , Stéphanie Briancon , Thierry Hoc , François Puel et al.
International Journal of Pharmaceutics, 2015, 490 (1-2), pp. 438-445. ⟨10.1016/j.ijpharm.2015.05.078⟩
Journal articles hal-01273157v1

Single-phase flow in a pulsed column: Particle Image Velocimetry validation of a CFD based model

A. Amokrane , S. Charton , F. Lamadie , J.F. Paisant , F. Puel et al.
Chemical Engineering Science, 2014, 114, pp.40-50. ⟨10.1016/j.ces.2014.04.003⟩
Journal articles hal-01273152v1

Precipitation and adsorption during fluoride removal from water by calcite in the presence of acetic acid

A. Ben Nasr , K. Walha , F. Puel , D. Mangin , R. Ben Amar et al.
Desalination and Water Treatment, 2014, 52 (10-12), pp.2231-2240. ⟨10.1080/19443994.2013.799441⟩
Journal articles hal-01273005v1

Development of a CFD-PBE coupled model for the simulation of the drops behaviour in a pulsed column

Abdenour Amokrane , Sophie Charton , Nida Sheibat-Othman , Julian Becker , Jean P. Klein et al.
Canadian Journal of Chemical Engineering, 2014, 92 (2), pp.220-233. ⟨10.1002/cjce.21933⟩
Journal articles hal-01273007v1

Coupled population balance–CFD simulation of droplet breakup in a high pressure homogenizer

Per Julian Becker , François Puel , Arend Dubbelboer , Jo Janssen , Nida Sheibat-Othman et al.
Computers & Chemical Engineering, 2014, 68, pp.140-150. ⟨10.1016/j.compchemeng.2014.05.014⟩
Journal articles hal-01273154v1

Development of an improved breakage kernel for high dispersed viscosity phase emulsification

Per Julian Becker , François Puel , Hugo Atle Jakobsen , Nida Sheibat-Othman
Chemical Engineering Science, 2014, 109, pp.326-338. ⟨10.1016/j.ces.2014.02.008⟩
Journal articles hal-01273019v1

Monitoring silicone oil droplets during emulsification in stirred vessel: Effect of dispersed phase concentration and viscosity

Per Julian Becker , François Puel , Yves Chevalier , Nida Sheibat-Othman
Canadian Journal of Chemical Engineering, 2014, 92 (2), pp.296-306. ⟨10.1002/cjce.21885⟩
Journal articles hal-01273011v1

New filterability and compressibility test cell design for nuclear products

J.P. Féraud , D. Bourcier , D. Ode , F. Puel
Nuclear Engineering and Design, 2013, 265, pp.288-293. ⟨10.1016/j.nucengdes.2013.06.036⟩
Journal articles hal-01273000v1

Actinides oxalate precipitation in emulsion modeling: From the drop scale to the industrial process

Sophie Charton , Amine Kacem , Abdenour Amokrane , Gilles Borda , François Puel et al.
Chemical Engineering Research and Design, 2013, 91 (4), pp.660-669. ⟨10.1016/j.cherd.2013.02.001⟩
Journal articles hal-01271829v1

In Situ Monitoring of Cocrystallization Processes - Complementary Use of Sensing Technologies

E. Gagniere , F. Puel , D. Mangin , J.-P. Valour , A. Rivoire et al.
Chemical Engineering and Technology, 2012, 35 (SI) (6), pp.1039-1044. ⟨10.1002/ceat.201100711⟩
Journal articles hal-01271824v1

Crystallization-in-emulsion process of a melted organic compound: In situ optical monitoring and simultaneous droplet and particle size measurements

Abir Khalil , François Puel , Xavier Cosson , Olga Gorbatchev , Yves Chevalier et al.
Journal of Crystal Growth, 2012, 342 (1), pp.99-109. ⟨10.1016/j.jcrysgro.2011.06.005⟩
Journal articles hal-01271819v1

Process induced transformations during tablet manufacturing: Phase transition analysis of caffeine using DSC and low frequency micro-Raman spectroscopy

Sébastien Hubert , Stéphanie Briancon , Alain Hédoux , Yannick Guinet , Laurent Paccou et al.
International Journal of Pharmaceutics, 2011, 420 (1), pp.76-83. ⟨10.1016/j.ijpharm.2011.08.028⟩
Journal articles hal-01271810v1

Cocrystal formation in solution: Inducing phase transition by manipulating the amount of cocrystallizing agent

Emilie Gagniere , Denis Mangin , François Puel , Jean-Pierre Valour , Jean-Paul Klein et al.
Journal of Crystal Growth, 2011, 316 (1), pp.118 - 125. ⟨10.1016/j.jcrysgro.2010.12.027⟩
Journal articles hal-01904869v1

Investigation of Discrete Population Balance Models and Breakage Kernels for Dilute Emulsification Systems

Per Julian Becker , François E. Puel , Reynald Henry , Nida Sheibat-Othman
Industrial and engineering chemistry research, 2011, 50, pp.11358-11374. ⟨10.1021/ie2006033⟩
Journal articles hal-00925079v1

Coupling between Membrane Processes and Crystallization Operations

Catherine Charcosset , Roland Kieffer , Denis Mangin , François Puel
Industrial and engineering chemistry research, 2010, 49 (12), pp.5489-5495. ⟨10.1021/ie901824x⟩
Journal articles hal-01271789v1

Study of droplet size distribution during an emulsification process using in situ video probe coupled with an automatic image analysis

Abir Khalil , François Puel , Yves Chevalier , Jean-Marc Galvan , Alain Rivoire et al.
Chemical Engineering Journal, 2010, 165 (3), pp.946-957. ⟨10.1016/j.cej.2010.10.031⟩
Journal articles hal-02844838v1

Precipitation of barium sulphate in a hollow fiber membrane contactor, Part I: Investigation of particulate fouling

Roland Kieffer , Denis Mangin , François Puel , Catherine Charcosset
Chemical Engineering Science, 2009, 64 (8), pp.1759-1767. ⟨10.1016/j.ces.2009.01.011⟩
Journal articles hal-01270944v1

Cocrystal Formation in Solution: In Situ Solute Concentration Monitoring of the Two Components and Kinetic Pathways

E. Gagnière , Denis Mangin , François Puel , C. Bebon , Jean-Paul Klein et al.
Crystal Growth & Design, 2009, 9 (8), pp.3376-3383. ⟨10.1021/cg801019d⟩
Journal articles hal-02102877v1

Formation of co-crystals: Kinetic and thermodynamic aspects

Emilie Gagnière , Denis Mangin , François Puel , Alain Rivoire , Olivier Monnier et al.
Journal of Crystal Growth, 2009, 311 (9), pp.2689-2695. ⟨10.1016/j.jcrysgro.2009.02.040⟩
Journal articles hal-01270958v1

Polymorphism in Processes of Crystallization in Solution: A Practical Review

D. Mangin , F. Puel , S. Veesler
Organic Process Research and Development, 2009, 13, pp.1241-1253
Journal articles hal-00440718v1

Precipitation of barium sulphate in a hollow fiber membrane contactor: Part II The influence of process parameters

Roland Kieffer , Denis Mangin , François Puel , Catherine Charcosset
Chemical Engineering Science, 2009, 64 (8), pp.1885-1891. ⟨10.1016/j.ces.2009.01.013⟩
Journal articles hal-01270948v1

Polymorphisme et transition de phases solides en solution

Denis Mangin , François Puel , S. Veesler
Les Techniques de l'Ingenieur, 2008, J2160, pp.1-10
Journal articles hal-01273265v1

Quantitative in situ monitoring of citric acid phase transition in water using Raman spectroscopy

Alexandre Caillet , François Puel , Gilles Fevotte
Chemical Engineering and Processing: Process Intensification, 2008, 47 (3), pp.377-382. ⟨10.1016/j.cep.2007.01.004⟩
Journal articles emse-00611868v1

Crystallization mechanisms of acicular crystals

F. Puel , E. Verdurand , P. Taulelle , C. Bebon , D. Colson et al.
Journal of Crystal Growth, 2008, 310 (1), pp.110-115
Journal articles hal-00269963v1

Understanding and modelling of crystallization mechanisms by in-situ analytical technologies monitoring

Manuel Henri , François E. Puel , Philippe D Perrichon , Caroline Wisniewski , Gilles Fevotte et al.
International Journal of Chemical Reactor Engineering, 2008, 6 (A3), pp.A3
Journal articles emse-00498786v1

Numerical simulation of mass transfer in a liquid–liquid membrane contactor for laminar flow conditions

Roland Kieffer , Catherine Charcosset , François Puel , Denis Mangin
Computers & Chemical Engineering, 2008, 32 (6), pp.1325-1333. ⟨10.1016/j.compchemeng.2007.06.013⟩
Journal articles hal-01270940v1

Industrial batch crystallization of a plate-like organic product. In situ monitoring and 2D-CSD modelling. Part 2: Kinetic modelling and identification

M. Oullion , F. Puel , G. Févotte , S. Righini , P. Carvin et al.
Chemical Engineering Science, 2007, 62 (3), pp.833-845. ⟨10.1016/j.ces.2006.08.078⟩
Journal articles hal-01272260v1

Industrial batch crystallization of a plate-like organic product. In situ monitoring and 2D-CSD modelling: Part 1: Experimental study

M. Oullion , F. Puel , G. Févotte , S. Righini , P. Carvin et al.
Chemical Engineering Science, 2007, 62 (3), pp.820-832. ⟨10.1016/j.ces.2006.08.077⟩
Journal articles hal-01270889v1

Effects of surfactants on crystallization of ethylene glycol distearate in oil-in-water emulsion

M.A. Bolzinger , C. Cogne , L. Lafferrere , F. Salvatori , P. Ardaud et al.
Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2007, 299 (1-3), pp.93-100. ⟨10.1016/j.colsurfa.2006.11.026⟩
Journal articles hal-01270892v1

Crystallization of Monohydrate Citric Acid. 1. In Situ Monitoring through the Joint Use of Raman Spectroscopy and Image Analysis

Alexandre Caillet , Alain Rivoire , Jean-Marc Galvan , François Puel , Gilles Fevotte et al.
Crystal Growth & Design, 2007, 7 (10), pp.2080-2087. ⟨10.1021/cg060557b⟩
Journal articles hal-01270895v1

In-line monitoring of partial and overall solid concentration during solvent-mediated phase transition using Raman spectroscopy

A. Caillet , F. Puel , G. Fevotte
International Journal of Pharmaceutics, 2006, 307 (2), pp.201-208. ⟨10.1016/j.ijpharm.2005.10.009⟩
Journal articles hal-01270880v1

Cristallisation : aspects théoriques

François Puel , S. Veesler , Denis Mangin
Techniques de l'Ingenieur, 2005, J2710, pp.1-16
Journal articles hal-01273260v1

Comparative scale-up of three methods for producing ibuprofen-loaded nanoparticles

Sergio A. Galindo-Rodríguez , François Puel , Stephanie Briançon , Eric Allémann , Eric Doelker et al.
European Journal of Pharmaceutical Sciences, 2005, 25 (4-5), pp.357-367. ⟨10.1016/j.ejps.2005.03.013⟩
Journal articles hal-01270840v1

Polymorphism in processes of crystallization in solution

S. Veesler , François Puel , Gilles Fevotte
STP Pharma Pratiques, 2005, 15 (1), pp.53-84
Journal articles hal-01270872v1

Applications of NIR spectroscopy to monitoring and analyzing the solid state during industrial crystallization processes

Gilles Fevotte , J. Calas , François Puel , C. Hoff
International Journal of Pharmaceutics, 2004, 273 (1-2), pp.159-169. ⟨10.1016/j.ijpharm.2004.01.003⟩
Journal articles hal-01270834v1

Investigation of the growth rate of β-cyclodextrin in water during both flow-cell and batch experiments

M. Kohl , F. Puel , J.P. Klein , C. Hoff , O. Monnier et al.
Journal of Crystal Growth, 2004, 270 (3-4), pp.633-645. ⟨10.1016/j.jcrysgro.2004.07.023⟩
Journal articles hal-01270837v1

Simulation and analysis of industrial crystallization processes through multidimensional population balance equations. Part 1: a resolution algorithm based on the method of classes

F. Puel , G. Févotte , J.P. Klein
Chemical Engineering Science, 2003, 58 (16), pp.3715-3727. ⟨10.1016/S0009-2509(03)00254-9⟩
Journal articles hal-01270738v1

Simulation and analysis of industrial crystallization processes through multidimensional population balance equations. Part 2: a study of semi-batch crystallization

F. Puel , G. Févotte , J.P. Klein
Chemical Engineering Science, 2003, 58 (16), pp.3729-3740. ⟨10.1016/S0009-2509(03)00253-7⟩
Journal articles hal-01270743v1

Real-time evaluation of the concentration of impurities during organic solution crystallization

L Derdour , G Févotte , François Puel , P Carvin
Powder Technology, 2003, 129 (1-3), pp.1-7. ⟨10.1016/S0032-5910(02)00283-8⟩
Journal articles hal-01270735v1

An Online Strategy To Increase the Average Crystal Size during Organic Batch Cooling Crystallization

F. Lewiner , G. Févotte , J. P. Klein , F. Puel
Industrial and engineering chemistry research, 2002, 41 (5), pp.1321-1328. ⟨10.1021/ie000962e⟩
Journal articles hal-01270730v1

On-line ATR FTIR measurement of supersaturation during solution crystallization processes. Calibration and applications on three solute/solvent systems

F Lewiner , J.P Klein , François Puel , G Févotte
Chemical Engineering Science, 2001, 56 (6), pp.2069-2084. ⟨10.1016/S0009-2509(00)00508-X⟩
Journal articles hal-01270722v1

Improving batch cooling seeded crystallization of an organic weed-killer using on-line ATR FTIR measurement of supersaturation

F. Lewiner , G. Févotte , J.P. Klein , F. Puel
Journal of Crystal Growth, 2001, 226 (2-3), pp.348-362. ⟨10.1016/S0022-0248(01)01395-1⟩
Journal articles hal-01270726v1

Habit Transient Analysis in Industrial Crystallization Using Two Dimensional Crystal Sizing Technique

F. Puel , P. Marchal , J. Klein
Chemical Engineering Research and Design, 1997, 75 (2), pp.193-205. ⟨10.1205/026387697523444⟩
Journal articles hal-01270718v1

Procédé de coulage sous pression pour la fabrication par voie directe de pastilles de combustible nucléaire : Influence des propriétés physiques des suspensions sur la filtrabilité

David Diaz , François Puel , Denis Ode , Emmanuelle Brackx , Franck Doreau et al.
SFGP2019, Oct 2019, Nantes, France
Conference papers hal-02535688v1

Bio-methane purification by adsorption technology: Optimization of operating parameters and adsorbent selection based on PSA process

Najib Chouikhi , Pluton Pullumbi , François Puel , Patrick Perré
International Conference on Fundamentals of Adsorption FOA, May 2019, Cairns, Australia
Conference papers hal-02536669v1

Bubble formation and detachment: an investigation by experiments and simulations

Wenbiao Jiang , Victor Pozzobon , Joel Casalinho , Thierry Martin , Patrick Perre et al.
8th International Colloids Conference, Jun 2018, Shanghai, China
Conference papers hal-01823145v1
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Experimental study of tensile strength of pharmaceutical tablets: effect of the diluent nature and compression pressure

Audrey Juban , Stephanie Briancon , François Puel , Thierry Hoc , Cécile Nouguier-Lehon et al.
Powders and Grains 2017 8th International Conference on Micromechanics of granular Media, Jul 2017, Montpellier, France. ⟨10.1051/epjconf/201714013002⟩
Conference papers hal-01820525v1

Solvolyse de la lignine

Aurélie Galfré , Emilie Gagniere , Isabelle Pitault , François Puel
SFGP2017, Jul 2017, Nancy, France
Conference papers hal-01823007v1
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Lignin solvolyse study

Aurélie Galfré , Emilie Gagniere , Isabelle Pitault , François Puel , Mélaz Tayakout-Fayolle et al.
19th International Symposium on the Wood, Fibre and Pulping Chemistry ISWFPC, Aug 2017, Porto Seguro, Brazil
Conference papers hal-01820534v1
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Influence de l'épaisseur de particule sur l'homogénéité de traitement thermique d'un bois de peuplier

John Pachón-Morales , Julien Colin , Floran Pierre , François Puel , Patrick Perré et al.
16ème Congrès de la Société Française de Génie des Procédés, Jul 2017, Nancy, France
Conference papers hal-01661843v1
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Flowability of lignocellulosic biomass powders: influence of torrefaction intensity

John Pachón-Morales , Julien Colin , Floran Pierre , Thibaut Champavert , François Puel et al.
Powders and Grains 2017: 8th International Conference on Micromechanics of Granular Media, Jul 2017, Montpellier, France. ⟨10.1051/epjconf/201714013017⟩
Conference papers hal-01661834v1
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Computational Filterability and dewatering determination based on shape and size distribution of solid suspensions

Danièle Bourcier , J.P Féraud , D. Ode , D Colson , François Puel et al.
12th World Filtration Congress (WFC12), Apr 2016, Taipei, Taiwan
Conference papers hal-01820512v1

Drop size distribution monitoring and modeling of oil-in-water emulsions in SMX+ static mixers.

Elodie Chabanon , Nida Sheibat-Othman , François Puel
DEFI Dynamic and Evolving Phases Interphases, Oct 2016, Solaize, France
Conference papers hal-01823137v1
Image document

Préparation d'alumine pour la catalyse : développement de nouveaux procédés de précipitation

Robin Lafficher , Mathieu Digne , Fabien Salvatori , Malika Boualleg , Didier Colson et al.
Colloque CRISTAL8, May 2016, Rouen, France
Conference papers hal-01822972v1
Image document

Development of new alumina precipitation routes for catalysis applications

Robin Lafficher , Mathieu Digne , Fabien Salvatori , Malika Boualleg , Didier Colson et al.
18th International Conference on Crystal Growth and Epitaxy, Aug 2016, Nagoya, Japan
Conference papers hal-01820517v1

New filterability and compressibility test cell design for nuclear product

Damien Bourcier , Jean-Pierre Feraud , Denis Ode , Colson Didier , François Puel et al.
Separation, Aug 2015, San Francisco, United States
Conference papers hal-01823070v1

Management of concentrate brine (reject water) produced from desalination processes

Barbara Malinowska , François Puel
Workshop Seawater Desalination using solar Energy, May 2015, Koweït City, Kuwait
Conference papers hal-01823052v1

Fluoride removal from water by a hybrid membrane process based on precipitation and microfiltration

Anis Ben Nasr , Khaled Walha , François Puel , Denis Mangin , Raja Ben Amar et al.
ECCE10 -10th Congress of Chemical Engineering, Sep 2015, Nice, France
Conference papers hal-01823114v1

Study and modelling of the dispersed phase behaviour in a pulsed column

Abdenour Amokrane , Sophie Charton , Sebastien Mass , François Puel
ECCE - 10th Congress of Chemical Engineering , Sep 2015, Nice, France
Conference papers hal-01823123v1

Influence of particle properties and working pressures on cake dewatering

Damien Bourcier , François Puel , Jean-Pierre Feraud , Denis Ode , Didier Colson et al.
ECCE10 - 10th Congress of Chemical Engi neering, Sep 2015, Nice, France
Conference papers hal-01823076v1

Nouveau procédé de préparation d'alumine pour la catalyse

Robin Lafficher , Mathieu D Digne , Fabien Salvatori , Malika Boualleg , Didier Colson et al.
Colloque Science et Technologie des Poudres, Poudre et Matériaux Frittés STPMF2015, Apr 2015, Nancy, France
Conference papers hal-01822946v1

Influence of particle properties on cake resistance and compressibility : a modelling study

Damien Bourcier , Jean-Pierre Feraud , Denis Ode , Didier Colson , François Puel et al.
European conference on Fluid separation Particle FPS2014, 2014, Lyon, France
Conference papers hal-01925109v1

State of the art: guidelines for the selection of fast precipitation devices

R. Lafficher , M. Digne , F. Salvatori , M. Boualleg , Didier Colson et al.
19th International Symposium on Industrial Crystallisation ISIC19, 2014, Toulouse, France
Conference papers hal-01920806v1

Crystallization-in-emulsion process: obtaining of primary nucleation rates thanks to an in situ video monitoring in stirred reactor

Thouaiba Htira , Emilie Gagnière , Abir Khalil , J.-M. Galvan , Alain Rivoire et al.
19th International Symposium on Industrial Crystallisation ISIC19, 2014, Toulouse, France
Conference papers hal-01925217v1

Etude de l\textquoterightécoulement turbulent dans une colonne pulsée par mesure PIV synchronisées

Abdenour Amokrane , F. Lamadie , J.F. Paisant , François Puel , Sophie Charton et al.
14ième congrès francophone de Techniques Laser CFTL2014, 2014, Marseille, Unknown Region
Conference papers hal-01925215v1

Transformation induite par le procédé industriel lors de la fabrication de comprimé : partie 3 - cartographie de la transition de phase solide de la caféine par micro-spectroscopie Raman

Sébastien Hubert , T. Manakul , D. Deligny , Stéphanie Briançon , A. Champagnon et al.
14ème Congrès de la Société Française de Génie des Procédés, Oct 2013, Lyon, France
Conference papers hal-01996656v1

New Filterability and Compressibility Test Cells for Nuclear Products

P. Feraud , D. Bourcier , D. Ode , François Puel
Filtech 2013, 2013, Wiesbaden, Germany
Conference papers hal-01925118v1

Crystallization in emulsion process: in situ video monitoring of the evolution of droplet and particle size distributions

Abir Khalil , François Puel , Emilie Gagnière , Jean-Marc Galvan , Alain Rivoire et al.
27th Conference of European Colloid and Interface Society – ECIS 2013, Sep 2013, Sofia, Bulgaria
Conference papers hal-01996665v1

Downsizing and wall effect on high pressure new filterability test cell

P. Feraud , D. Bourcier , L. Salemi , D. Ode , François Puel et al.
AFS2013 Fall conference, 2013, Cincinnati, USA, Unknown Region
Conference papers hal-01925231v1

Coupling of Population Balance Modelling to Computational Fluid Dynamics

Julian Becker , François Puel , Nida Sheibat -Othman
Multimod ITN : 3rd Workshop, 2013, Chalkidiki, Greece
Conference papers hal-01925232v1

Transformation induite par le procédé industriel lors de la fabrication de comprimé : Étude de la transition polymorphique d'un principe actif modèle (caféine)

Sébastien Hubert , Stéphanie Briançon , A. Heydoux , D. Deligny , Cécile Nouguier-Lehon et al.
14ème Congrès de la Société Française de Génie des Procédés, Oct 2013, Lyon, France
Conference papers hal-01996659v1

A Coupled Population Balance CFD Framework in OpenFoam for a High-Pressure Homogenizer

Per Julian Becker , François Puel , Arend Dubbelboer , Nida Sheibat-Othman
Récents Progrès en Génie des Procédés, 2013, Lyon, France
Conference papers hal-01925249v1

Transformation induite par le procédé industriel lors de la fabrication de comprimé : partie 1 Analyse de la transition de phase de caféine par ACD et MSR-BF

Sébastien Hubert , Stéphanie Briançon , A. Heydoux , Yannick Guinet , Laurent Paccou et al.
14ème Congrès de la Société Française de Génie des Procédés, Oct 2013, Lyon, France
Conference papers hal-01996658v1

Procédé de cristallisation en émulsion en réacteur agité : suivi vidéo in situ de l'évolution des distributions de tailles de gouttes et de particules

Abir Khalil , François Puel , Yves Chevalier , Alain Rivoire , Jean-Paul Klein et al.
14ème Congrès de la Société Française de Génie des Procédés, Oct 2013, Lyon, France
Conference papers hal-01996660v1

In situ monitoring of the droplet size distribution of o/w emulsion during the emulsification process

Abir Khalil , François Puel , Alain Rivoire , J.-P. Klein , Y. Chevalier et al.
27th European conference of colloid and interface society ECIS, Sep 2013, sofia, Bulgaria
Conference papers hal-01996704v1

Procédé de cristallisation en émulsion : obtention des paramètres de nucléation primaire au moyen d'un suivi vidéo in situ en réacteur agité

Thouaiba Htira-Ezzi , Abir Khalil , François Puel , Emilie Gagnière , Jean-Marc Galvan et al.
Cristal 7, May 2013, Toulouse-Albi, France. pp.1--9
Conference papers hal-02001475v1

Micro-Raman spectroscopy of Pharmaceuticals and Bio-pharmaceuticals induced by manufacturing stresses

Laurent Paccou , Yannick Guinet , Sébastien Hubert , Stéphanie Briançon , François Puel et al.
International Discussion Meeting on Relaxations in complex systems IDMRCS7, Jul 2013, Barcelona, Spain
Conference papers hal-01996655v1

Transformation induite par le procédé industriel lors de la fabrication de comprimé : partie 2 - analyse de la densité dans le volume et en surface des comprimés par micro-tomographie aux rayons X et micro-indentation

Sébastien Hubert , M. Berot , Cécile Nouguier-Lehon , Stéphanie Briançon , T. Hoc et al.
14ème Congrès de la Société Française de Génie des Procédés, Oct 2013, Lyon, France
Conference papers hal-01996657v1

New filterability and compressibility cell test design for nuclear product

P. Feraud , D. Bourcier , D. Ode , François Puel
Récents Progrès en Génie des Procédés, 2013, Lyon, France
Conference papers hal-01925123v1

Process Induced Transformations (PITs) during tablet manufacturing: Mapping of caffeine phase transition using High Frequency Micro-Raman Spectroscopy (HF-MRS)

Sébastien Hubert , T. Manakul , D. Deligny , Stéphanie Briançon , A. Champagnon et al.
Journée Scientifique de l’Institut de Chimie de Lyon, Oct 2012, Villeurbanne, France
Conference papers hal-02001473v1

Oxalate Precipitation in Emulsion: from the Drop Scale to the Industrial Process

Abdenour Amokrane , Amine Kacem , Sophie Charton , François Puel , Jean-Paul Klein et al.
International Conference on Nuclear Chemistry for Sustainable Fuel Cycles (ATALANTE), Sep 2012, Montpellier, France. pp.456-459, ⟨10.1016/j.proche.2012.10.069⟩
Conference papers hal-01272092v1

Coupling Population Balance Modeling to Computational Fluid Dynamics in a High-Pressure Homogenizer

Julian Becker , François Puel , Arend Dubbelboer , Nida Sheibat -Othman
25th Meetings J. Cartier : Emulsification : Modeling Applications and Technologies, 2012, Lyon, France
Conference papers hal-01925241v1

On the solution of the population balance model describing breakage dominated emulsification: Evaluation of weighted residual methods

J. Solsvik , Per Julian Becker , François Puel , H.A. Jakobsen
25th Meetings J. Cartier : Emulsification : Modeling Applications and Technologies, 2012, Lyon, France
Conference papers hal-01920814v1

Crystallization-In-Emulsion Process: Extraction of Primary Nucleation Rates from experiments Performed in stirred reactor

A. Khalil , F. Puel , Emilie Gagnière , Jean-Paul Klein
10th International Workshop on Crystal Growth of Organic Materials CGOM10, 2012, Limerick, Ireland
Conference papers hal-01925236v1

Population balance model: breakage kernel parameter fitting to emulsification data

J. Solsvik , Per Julian Becker , François Puel , H.A. Jakobsen
25th Meetings J. Cartier : Emulsification : Modeling Applications and Technologies, 2012, Lyon, France
Conference papers hal-01920815v1

Process induced transformations (PITs) during tablet manufacturing: Phase transition analysis of caffeine using DSC and low frequency micro-Raman spectroscopy

Sébastien Hubert , Stéphanie Briançon , A. Heydoux , Yannick Guinet , Laurent Paccou et al.
12th International conference on Pharmacy and Applied Physical Chemistry PhandTA12, May 2012, Graz, France
Conference papers hal-02001480v1

Characterization of density distribution in formulated tablets using X-ray micro-computed tomography and micro-indentation

Sébastien Hubert , M. Berot , Stéphanie Briançon , Cécile Nouguier-Lehon , T. Hoc et al.
12th International conference on Pharmacy and Applied Physical Chemistry PhandTA12, May 2012, Graz, Austria
Conference papers hal-02001479v1

Study of the dispersed phase behaviour in a pulsed column for oxalate precipitation in emulsion

Abdenour Amokrane , Sophie Charton , F. Lamadie , Julian Becker , J.-P. Klein et al.
25th Meetings J. Cartier : Emulsification : Modeling Applications and Technologies, 2012, Lyon, France
Conference papers hal-01920820v1

Micro-Raman spectroscopy of caffeine polymorphs in tablets: comparison between low and high frequency investigations

Sébastien Hubert , T. Manakul , D. Deligny , A. Heydoux , Y. Guynet et al.
Fourteenth International Workshop on Physical characterization of Pharmaceutical Solids IWPCPS14, Jun 2012, Barcelone, Spain
Conference papers hal-02001465v1

Study of the dispersed phase behaviour in a pulsed column for oxalate precipitation in emulsion

Abdenour Amokrane , Sophie Charton , F. Lamadie , Jean-Paul Klein , François Puel et al.
20th International Congress of Chemical and Process Engineering CHISA, 2012, Prague, République Tchéque, Unknown Region
Conference papers hal-01920816v1

Coupling of discrete population balance to CFD in OpenFOAM

Julian Becker , François Puel , Nida Sheibat -Othman
Multimod ITN : 2nd Workshop, 2012, Milan, Italy
Conference papers hal-01925233v1

Application des mécanismes fondamentaux de la cristallisation en solution : des succès, des avancées et des challenges.

François Puel
Colloque CEA Journées Scientifiques de Marcoule 2012, Jun 2012, Marcoule, France
Conference papers hal-01275510v1

Transition de phases solides des principes actifs en compression : application à la caféine

Alain Hédoux , T. Hoc , Hatem Fessi , François Puel , Sébastien Hubert et al.
4ème Journée partenariale de l’Institut Carnot, Oct 2012, Lyon, France
Conference papers hal-02001471v1

Process induced transformations (PITs) during tablet manufacturing: Phase transition analysis of caffeine using DSC and low frequency micro-Raman spectroscopy

Sébastien Hubert , Stéphanie Briançon , A. Heydoux , Yannick Guinet , Laurent Paccou et al.
8th World meeting on Pharmaceutics, Bio-pharmaceutics and Pharmaceutical Technology, Mar 2012, Istanbul, Turkey
Conference papers hal-02001481v1

Modeling of the dispersed liquid phase behavior in a pulsed column for oxalate precipitation in emulsion

Abdenour Amokrane , Sophie Charton , F. Lamadie , Per Julian Becker , Jean Paul Klein et al.
9th International Conference on Computational Fluid dynamics in the Minerals and Process Industries CFD2012, 2012, Melbourne, Australia
Conference papers hal-01925124v1

Transformations Induites par les Procédés d'Industrialisation (TIPI's) lors de la fabrication de comprimés : Mesure du taux de transformation de la caféine par DSC et micro spectroscopie Raman basse fréquence

Sébastien Hubert , Stéphanie Briançon , A. Heydoux , Yannick Guinet , Laurent Paccou et al.
Journées Scientifiques de l’Institut de Chimie de Lyon, Jun 2011, Villeurbanne, France
Conference papers hal-02001474v1

In situ monitoring of cocrystallization process in solution: complementary use of sensing technologies

E. Gagniere , François E. Puel , Denis Mangin , Jean Pierre Valour , Alain Rivoire et al.
18th International Workshop on Industrial Crystallization BIWIC 2011, Sep 2011, Delft, Netherlands
Conference papers hal-02110464v1

Etude du procédé de co-cristallisation de molécules d’intérêt pharmaceutique

Emilie Gagniere , D. Mangin , François E. Puel , Alain Rivoire , Jean Paul Klein et al.
Journées CRISTECH 2010, Oct 2010, Autrans, France
Conference papers hal-02113645v1

Application des mécanismes fondamentaux de la cristallisation à la cristallisation industrielle en solution

François Puel
CRISTAL 6, CINaM, May 2010, Lyon, France. pp.28
Conference papers hal-01275500v1

Etude du procédé de co-cristallisation de molécules d’intérêt pharmaceutique - Partie 2 : Contrôle de la phase formée

Emilie Gagniere , D. Mangin , François E. Puel , Jean Paul Klein , Olivier Monnier et al.
CRISTAL 6, May 2010, Marseille, France
Conference papers hal-02112061v1

In Situ video monitoring of crystallisable emulsions : study of droplet size distribution

Abir Khalil , François Puel , Yves Chevalier , Jean-Marc Galvan , Alain Rivoire et al.
WCE 2010 World Congress of Emulsions, Oct 2010, Lyon, France
Conference papers hal-02001482v1

Formation of carbamazepine-nicotinamide cocrystals: kinetic aspects

Emilie Gagniere , D. Mangin , François E. Puel , Jean Paul Klein , Olivier Monnier et al.
9th International Workshop on Crystal Growth of Organic Materials CGOM9, Aug 2010, Singapore, Singapore
Conference papers hal-02112067v1

Procédé de formulation par cristallisation en émulsion : Dispositif de suivi in situ et premières observations

Abir Khalil , Xavier Cosson , François Puel , Yves Chevalier , Alain Rivoire et al.
Récents Progrès en Génie des Procédés, CRISTAL 6, May 2010, Marseille, France. pp.266--273
Conference papers hal-02001476v1

Etude du procédé de co-cristallisation de molécules d’intérêt pharmaceutique - Partie 1 : Chemins cinétiques de cristallisation

Emilie Gagniere , D. Mangin , François E. Puel , Jean Paul Klein , Olivier Monnier et al.
CRISTAL 6, May 2010, Marseille, France
Conference papers hal-02112057v1

Procédé de formulation par cristallisation en émulsion : etude de la distribution en taille de gouttes par video in situ

Abir Khalil , François Puel , Yves Chevalier , Alain Rivoire , Jean-Paul Klein et al.
12ème Congrès de la Société Française de Génie des Procédés, Oct 2009, Marseille, France
Conference papers hal-02001477v1

Formation des co-cristaux carbamazepine-nicotinamide : Impact des paramètres de procédés

Emilie Gagniere , D. Mangin , François E. Puel , Alain Rivoire , Jean Paul Klein et al.
CRISTAL 5, May 2008, Lyon, France
Conference papers hal-02112045v1

Formation of carbamazepine-nicotinamide co-crystals : Impact of process parameters

Emilie Gagniere , D. Mangin , François E. Puel , Alain Rivoire , Jean Paul Klein et al.
17th International Symposium on Industrial Crystallisation ISIC17- CGOM8, Sep 2008, Maastrich, Netherlands
Conference papers hal-02110413v1

Application de la spectroscopie moyen infra rouge in situ au développement et au contrôle des procédés de cristallisation en solution

François Puel , Gilles Fevotte
Congrès CRISTAL 2, Nov 2003, Toulouse, France
Conference papers hal-01275499v1

Applications of infrared spectroscopy for the mastery of crystallization of organic materials

François Puel , Gilles Fevotte
Workshop CGCOM6, Aug 2003, Glasgow, United Kingdom
Conference papers hal-01275496v1

Polymorphism in fine organic processes

François Puel , J.P. Klein
Workshop Sympocrist CRMC2, Sep 2002, Marseille, France
Conference papers hal-01275492v1
Image document

Lignin solvolyse study

Aurélie Galfré , Isabelle Pitault , Mélaz Tayakout-Fayolle , François Puel , Emilie Gagnière et al.
25th International Symposiusm on Chemical Reaction Engineering ISCRE25, May 2018, Florence, Italy. 25th International Symposiusm on Chemical Reaction Engineering ISCRE25
Conference poster hal-01820538v1

Fluoride removal from water by calcite and acid addition followed by microfiltration

Anis Ben Nasr , Khaled Walha , François Puel , Denis Mangin , Raja Ben Amar et al.
Conference on desalination for the environment, clean water and energy, May 2014, Limassol, Cyprus
Conference poster hal-02097022v1

Procédé de cristallisation en émulsion en réacteur agité : suivi vidéo in situ de l’évolution des distributions de tailles de gouttes et de particules

Abir Khalil , François E. Puel , Emilie Gagniere , Yves Chevalier , Jean-Marc Galvan et al.
Congrès XIVème SFG, Oct 2013, Lyon, France
Conference poster hal-02113832v1

Co-cristallisation de carbamazépine-nicotinamide : aspects cinétiques et thermodynamiques

Emilie Gagniere , D. Mangin , François E. Puel , Alain Rivoire , Jean Paul Klein et al.
Journées CRISTECH, Oct 2008, Ile d'Oléron, France
Conference poster hal-02113853v1

Emulsions

Y. Chevalier , Marie-Alexandrine Bolzinger , François Puel
Anne-Marie PENSE-LHERITHIER. Conception des produits cosmétiques : La formulation , Chapitre 7, Lavoisier SA, pp.163-220, 2015
Book sections hal-01273270v1

Crystallization of Pharmaceutical Crystals

S. Veesler , François Puel
Tatau Nishinaga. Handbook of Crystal Growth, 1-A (Chapitre 21), Elsevier, pp.915-949, 2014, Fundamentals : Thermodynamics and Kinetics, 9780444563699. ⟨10.1016/B978-0-444-56369-9.00021-6⟩
Book sections hal-01273239v1

Co-crystallization in solution and scale-up issues

Emilie Gagniere , Denis Mangin , S. Veesler , François Puel
Johan Wouters, Luc Quéré. Pharmaceutical salts and co-crystals, chapitre 9, Royal Society of Chemistry, pp.188-211, 2012, RSC Drug Discovery Series, 978-1-84973-158-4. ⟨10.1039/9781849733502-00188⟩
Book sections hal-01273214v1

Industrial technologies and scale up

François Puel , Stephanie Briançon , Hatem Fessi
S. Benita. Microencapsulation : methods and industrial applications , 158, CRC Press Taylor & Francis group, pp.149-182, 2006, Drugs and Pharmaceutical Science, 978-0-8247-2317-0. ⟨10.1201/9781420027990.fmatt⟩
Book sections hal-01273208v1