Frédéric Cassé

Research Engineer in biology
42
Documents
Identifiants chercheurs

Présentation

Publications

4
3
4
9
3
1
5
1
2
2
2
2
2
2
5
5
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
16
6
6
4
3
3
2
2
1

Publications

Mechanical Stimulation of Equine Bone Marrow Mesenchymal Stromal Cell-Derived Cartilage-Like In Vitro Model Triggers Osteoarthritis Features

Romain Contentin , Cassie Jehl , Kevin Commenchail , Florence Legendre , Philippe Galéra et al.

ACS Biomaterials Science and Engineering, 2025, ⟨10.1021/acsbiomaterials.5c00500⟩

Article dans une revue hal-05131501v1
Deposit thumbnail

L’arthrose chez le cheval : des thérapies innovantes

Florence Legendre , Frédéric Cassé , Romain Contentin , Lélia Bertoni , Magali Demoor et al.

L'actu des labos normands en santé équine, 2024, 1, pp.8-9

Article dans une revue hal-04780982v1
Deposit thumbnail

Equine osteoarthritis: Strategies to enhance mesenchymal stromal cell-based acellular therapies

Manon Jammes , Romain Contentin , Frédéric Cassé , Philippe Galéra

Frontiers in Veterinary Science, 2023, 10 (1115774), ⟨10.3389/fvets.2023.1115774⟩

Article dans une revue hal-04042900v1
Deposit thumbnail

Effect of pro-inflammatory cytokine priming and storage temperature of the mesenchymal stromal cell (MSC) secretome on equine articular chondrocytes

Manon Jammes , Romain Contentin , Fabrice Audigié , Frédéric Cassé , Philippe Galéra

Frontiers in Bioengineering and Biotechnology, 2023, 11, pp.1204737. ⟨10.3389/fbioe.2023.1204737⟩

Article dans une revue hal-04197029v1
Deposit thumbnail

Pro-Inflammatory Cytokine Priming and Purification Method Modulate the Impact of Exosomes Derived from Equine Bone Marrow Mesenchymal Stromal Cells on Equine Articular Chondrocytes

Manon Jammes , Frédéric Cassé , Emilie Velot , Arnaud Bianchi , Fabrice Audigié et al.

International Journal of Molecular Sciences, 2023, 24 (18), pp.14169. ⟨10.3390/ijms241814169⟩

Article dans une revue hal-04221506v1
Deposit thumbnail

Bone Marrow MSC Secretome Increases Equine Articular Chondrocyte Collagen Accumulation and Their Migratory Capacities

Romain Contentin , Manon Jammes , Bastien Bourdon , Frédéric Cassé , Arnaud Bianchi et al.

International Journal of Molecular Sciences, 2022, 23 (10), pp.5795. ⟨10.3390/ijms23105795⟩

Article dans une revue hal-03695375v1
Deposit thumbnail

Functionalized Nanogels with Endothelin-1 and Bradykinin Receptor Antagonist Peptides Decrease Inflammatory and Cartilage Degradation Markers of Osteoarthritis in a Horse Organoid Model of Cartilage

Aurélie Cullier , Frédéric Cassé , Seng Manivong , Romain Contentin , Florence Legendre et al.

International Journal of Molecular Sciences, 2022, 23 (16), pp.8949. ⟨10.3390/ijms23168949⟩

Article dans une revue hal-03775355v1

Synaptic Adhesion Molecules Regulate the Integration of New Granule Neurons in the Postnatal Mouse Hippocampus and their Impact on Spatial Memory

Marine Krzisch , Christine Fülling , Laura Jabinet , Jan Armida , Elias Gebara et al.

Cerebral Cortex, 2022, ⟨10.1093/cercor/bhw217⟩

Article dans une revue hal-03896703v1
Deposit thumbnail

Marine Collagen Hydrolysates Downregulate the Synthesis of Pro-Catabolic and Pro-Inflammatory Markers of Osteoarthritis and Favor Collagen Production and Metabolic Activity in Equine Articular Chondrocyte Organoids

Bastien Bourdon , Romain Contentin , Frédéric Cassé , Chloé Maspimby , Sarah Oddoux et al.

International Journal of Molecular Sciences, 2021, 22 (2), pp.580. ⟨10.3390/ijms22020580⟩

Article dans une revue hal-03114578v1
Deposit thumbnail

Marine Collagen Hydrolysates Promote Collagen Synthesis, Viability and Proliferation While Downregulating the Synthesis of Pro-Catabolic Markers in Human Articular Chondrocytes

Bastien Bourdon , Frédéric Cassé , Nicolas Gruchy , Pierre Cambier , Sylvain Leclercq et al.

International Journal of Molecular Sciences, 2021, 22 (7), pp.3693-3718. ⟨10.3390/ijms22073693⟩

Article dans une revue hal-03215150v1
Deposit thumbnail

The synaptic balance between sumoylation and desumoylation is maintained by the activation of metabotropic mGlu5 receptors

Lenka Schorova , Marie Pronot , Gwenola Poupon , Marta Prieto , Alessandra Folci et al.

Cellular and Molecular Life Sciences, 2019, 76 (15), pp.3019-3031. ⟨10.1007/s00018-019-03075-8⟩

Article dans une revue inserm-02474777v1

Mossy Cells Control Adult Neural Stem Cell Quiescence and Maintenance through a Dynamic Balance between Direct and Indirect Pathways

Chia-Yu Yeh , Brent Asrican , Jonathan Moss , Luis Jhoan Quintanilla , Ting He et al.

Neuron, 2018, 99 (3), pp.493-510.e4. ⟨10.1016/j.neuron.2018.07.010⟩

Article dans une revue hal-03896715v1
Deposit thumbnail

Sumoylation regulates FMRP-mediated dendritic spine elimination and maturation

Anouar Khayachi , Carole Gwizdek , Gwénola Poupon , Damien Alcor , Magda Chafai et al.

Nature Communications, 2018, 9 (1), pp.757. ⟨10.1038/s41467-018-03222-y⟩

Article dans une revue inserm-02443557v1

Sumoylation regulates FMRP-mediated dendritic spine elimination and maturation

Anouar Khayachi , Carole Gwizdek , Gwénola Poupon , Damien Alcor , Magda Chafai et al.

Nature Communications, 2018, 9 (1), ⟨10.1038/s41467-018-03222-y⟩

Article dans une revue hal-03039173v1

Astrocytes’ Contribution to Adult Neurogenesis in Physiology and Alzheimer’s Disease

Frédéric Cassé , Kevin Richetin , Nicolas Toni

Frontiers in Cellular Neuroscience, 2018, 12, pp.432. ⟨10.3389/fncel.2018.00432⟩

Article dans une revue hal-03789897v1

Sumoylation regulates FMRP-mediated dendritic spine elimination and maturation

Anouar Khayachi , Carole Gwizdek , Gwénola Poupon , Damien Alcor , Magda Chafai et al.

Nature Communications, 2018, 9 (1), ⟨10.1038/s41467-018-03222-y⟩

Article dans une revue hal-03084675v1

Interactions between N -Ethylmaleimide-sensitive factor and GluA2 contribute to effects of glucocorticoid hormones on AMPA receptor function in the rodent hippocampus

Hui Xiong , Frédéric Cassé , Ming Zhou , Zhi-Qi Xiong , Marian Joels et al.

Hippocampus, 2016, 26 (7), pp.848-856. ⟨10.1002/hipo.22567⟩

Article dans une revue istex inserm-03494824v1
Deposit thumbnail

mTOR is essential for corticosteroid effects on hippocampal AMPA receptor function and fear memory

Hui Xiong , Frédéric Cassé , Yang Zhou , Ming Zhou , Zhi-Qi Xiong et al.

Perceptual and Motor Skills, 2015, 22 (12), pp.577-583. ⟨10.1101/lm.039420.115⟩

Article dans une revue hal-03930835v1
Deposit thumbnail

Synaptic Integration of Adult-Born Hippocampal Neurons Is Locally Controlled by Astrocytes.

Sébastien Sultan , Liyi Li , Jonathan Moss , Francesco Petrelli , Frédéric Cassé et al.

Neuron, 2015, 88 (5), pp.957-972. ⟨10.1016/j.neuron.2015.10.037⟩

Article dans une revue hal-02882611v1

mGlu5 receptors regulate synaptic sumoylation via a transient PKC-dependent diffusional trapping of Ubc9 into spines

Céline Loriol , Frédéric Cassé , Anouar Khayachi , Gwénola Poupon , Magda Chafai et al.

Nature Communications, 2014, 5 (1), ⟨10.1038/ncomms6113⟩

Article dans une revue hal-03039214v1

mGlu5 receptors regulate synaptic sumoylation via a transient PKC-dependent diffusional trapping of Ubc9 into spines

Céline Loriol , Frédéric Cassé , Anouar Khayachi , Gwénola Poupon , Magda Chafai et al.

Nature Communications, 2014, 5 (1), ⟨10.1038/ncomms6113⟩

Article dans une revue hal-03084688v1

Protein Sumoylation in Brain Development, Neuronal Morphology and Spinogenesis.

Carole Gwizdek , Frédéric Cassé , Stéphane Martin

NeuroMolecular Medicine, 2013, epub ahead of print. ⟨10.1007/s12017-013-8252-z⟩

Article dans une revue hal-00855033v1

Protein Sumoylation in Brain Development, Neuronal Morphology and Spinogenesis

Carole Gwizdek , Frédéric Cassé , Stéphane Martin

NeuroMolecular Medicine, 2013, 15 (4), pp.677-691. ⟨10.1007/s12017-013-8252-z⟩

Article dans une revue hal-03084691v1

Glutamate controls tPA recycling by astrocytes, which in turn influences glutamatergic signals.

Frédéric Cassé , Isabelle Bardou , Lydia Danglot , Aurélien Briens , Axel Montagne et al.

Journal of Neuroscience, 2012, 32 (15), pp.5186-99. ⟨10.1523/JNEUROSCI.5296-11.2012⟩

Article dans une revue hal-00786439v1

Tissue‐type plasminogen activator induces plasmin‐dependent proteolysis of intracellular neuronal nitric oxide synthase

Amandine Baron , Yannick Hommet , Frédéric Cassé , Denis Vivien

Biology of the Cell, 2012, 102 (10), pp.539-547. ⟨10.1042/BC20100072⟩

Article dans une revue hal-05509921v1

Antibodies Preventing the Interaction of Tissue-Type Plasminogen Activator With N-Methyl- d -Aspartate Receptors Reduce Stroke Damages and Extend the Therapeutic Window of Thrombolysis

Richard Macrez , Pauline Obiang , Maxime Gauberti , Benoit Roussel , Amandine Baron et al.

Stroke, 2011, 42 (8), pp.2315-2322. ⟨10.1161/STROKEAHA.110.606293⟩

Article dans une revue hal-03895712v1

Antibodies Preventing the Interaction of Tissue-Type Plasminogen Activator With N-Methyl- d -Aspartate Receptors Reduce Stroke Damages and Extend the Therapeutic Window of Thrombolysis

Richard Macrez , Pauline Obiang , Maxime Gauberti , Benoit Roussel , Amandine Baron et al.

Stroke, 2011, 42 (8), pp.2315-2322. ⟨10.1161/STROKEAHA.110.606293⟩

Article dans une revue hal-05509915v1

Tissue-type plasminogen activator induces plasmin-dependent proteolysis of intracellular neuronal nitric oxide synthase

Amandine Baron , Yannick Hommet , Frédéric Cassé , Denis Vivien

Biology of the Cell, 2010, 102 (10), pp.539-547. ⟨10.1042/bc20100072⟩

Article dans une revue hal-03895701v1

NR2D-containing NMDA receptors mediate tissue plasminogen activator-promoted neuronal excitotoxicity

A Baron , A Montagne , Frédéric Cassé , S Launay , E Maubert et al.

Cell Death and Differentiation, 2010, 17 (5), pp.860-871. ⟨10.1038/cdd.2009.172⟩

Article dans une revue hal-03895693v1

Small extracellular vesicles as biomarkers candidates for moderate asthma of horses: A proteomic investigation

Eliott Schmitt , Anne Courouce , Marie-Pierre Toquet , Margot Bègue , Benoit Bernay et al.

43th Annual VCRS Comparative Meeting, Veterinary Comparative Respiratory Society, Sep 2025, Magog, Canada

Communication dans un congrès hal-05285231v1

Mesenchymal stromal cells-derived exosomes: a new treatment for horse osteoarthritis?

Frédéric Cassé , Manon Jammes , Émilie Velot , Arnaud Bianchi , Fabrice Audigié et al.

FSEV Meeting 2023, Société Française des vésicules extracellulaires, Nov 2023, On line, France

Communication dans un congrès hal-04347467v1

Injection intra-articulaire d’un nanogel fonctionnalisé combinant des effets mécanique et biologique rémanents contre l’arthrose chez le cheval : étude de tolérance

A. Terlinden , Sandrine Jacquet , Aurélie Cullier , Frédéric Cassé , F. Legendre et al.

50ème Journées annuelles de l'AVEF, Nov 2022, Reims, France

Communication dans un congrès hal-04004349v1

The secretome of equine bone marrow-derived mesenchymal stem cells enhanced regenerative phenotype of equine articular chondrocytes

Manon Jammes , Romain Contentin , Frédéric Cassé , Bastien Bourdon , Arnaud Bianchi et al.

Journées de l'Ecole Doctorale Normande de Biologie Intégrative, Santé, Environnement (nBISE) - 24e édition, Jun 2022, Caen, France

Communication dans un congrès hal-03728083v1

Study of therapeutic potential of new functionalized nanogels against osteoarthritis by using equine cartilage organoid cultures

Aurélie Cullier , Frédéric Cassé , Florence Legendre , Romain Contentin , Seng Manivong et al.

Journée Normande de Recherche Biomédicale, Jun 2022, Rouen, France

Communication dans un congrès hal-03722806v1

Functionalized Nanohydrogels decrease Inflammatory and Cartilage Degradation Biomarkers in an organoid model of horse cartilage tissue

Aurélie Cullier , Romain Contentin , Frédéric Cassé , Florence Legendre , Seng Manivong et al.

XXIIIème Journées de l'Ecole Doctorale Normande de Biologie Intégrative Santé et Environnement, May 2021, CAEN, France

Communication dans un congrès hal-03229755v1

Proteomic Profiling of Respiratory Small Extracellular Vesicles Reveals Biomarkers Candidates for Moderate Equine Asthma

Eliott Schmitt , Anne Courouce , Marie-Pierre Toquet , Margot Bègue , Benoit Bernay et al.

Hong Kong Jockey Club International Conference 2025, Dec 2025, Hong Kong, China

Poster de conférence hal-05285260v1

Comparative proteomics of small extracellular vesicles reveals immune-related biomarkers in moderate equine asthma

Eliott Schmitt , Anne Courouce , Marie-Pierre Toquet , Margot Bègue , Benoit Bernay et al.

Journées de Recherche Respiratoire, Oct 2025, Caen, France

Poster de conférence hal-05285287v1

Immunomodulatory effects of plasma-derived extracellular vesicles on equine alveolar macrophages

Meriem Rami , Eliott Schmitt , Marie-Pierre Toquet , Erika Hue , Sandra Audonnet et al.

42th Annual VCRS Comparative Meeting, Nov 2024, Levi, Finland

Poster de conférence hal-04781094v1

Comparative analysis of small extracellular vesicles isolation strategies in equine plasma

Eliott Schmitt , Marie-Pierre Toquet , Sandra Audonnet , Didier Goux , Valérie Picandet et al.

Journées de l'école doctorale Normandie de Biologie Intégrative, Santé et Environnement, May 2024, Caen, France

Poster de conférence hal-04766702v1

Functionalized Nanogels decrease Inflammatory and Cartilage Degradation markers of Osteoarthritis in a horse organoid model of cartilage

Aurélie Cullier , Romain Contentin , Frédéric Cassé , Florence Legendre , Seng Manivong et al.

International Cartilage Regeneration & joint Preservation Society, Apr 2022, Berlin, Germany

Poster de conférence hal-03653007v1
Deposit thumbnail

The secretome of equine bone marrow-derived mesenchymal stem cells enhanced regenerative phenotype of equine articular chondrocytes

Manon Jammes , Romain Contentin , Frédéric Cassé , Bastien Bourdon , Arnaud Bianchi et al.

International Society of Extracellular Vesicles Congress 2022 (ISEV2022), May 2022, Lyon, France

Poster de conférence hal-03710365v1

Intra-articular injection of a functionalized nanogel combining prolonged mechanical and biological effects as a treatment for osteoarthritis in the horse: a double-blinded, randomized tolerance study

A. Terlinden , Sandrine Jacquet , Aurélie Cullier , Frédéric Cassé , Florence Legendre et al.

Journées Normandes de la Recherche Biomédicale, Jun 2022, Rouen, France

Poster de conférence hal-04003400v1