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Frédérique FAVIER

9
Documents
Identifiants chercheurs

Présentation

After a PhD in protein crystallography in Strasbourg in the laboratory of D. Moras, I was recruited in 1995 as an assistant professor at the University of Nancy, now University of Lorraine, France. I carry out my research work in the BioMod team at the CRM2 (UMR CNRS-UL 7036). I am currently involved in two main research projects. - The first one concerns glutathione transferases. Although the first structures were established about thirty years ago, the diversity of these proteins throughout living organisms reveals roles that are complex and still poorly known, particularly in plants and fungi. In collaboration with the team of Pr. E. Gelhaye (IAM laboratory, Nancy), we have more than 10 years of experience in the analysis of the structure of these proteins, especially in complex with specialized metabolites, in relation with their function. - My second research area concerns horizontal gene transfer via integrative and conjugative elements (ICE) in Streptococcus thermophilus, a Gram-positive bacterium. We analyze the structures of proteins involved in the early stage of conjugation and in the transfer through the type IV secretion system, in collaboration with Drs N. Soler and B. Douzi in the ICE-TeA team led by Pr. N. Leblond-Bourget (DynAMic laboratory in Nancy) who are long-time specialists in the field. - Previously, I worked for a long time on methionine sulfoxide reductases, which are protective proteins against oxidative stress.

Publications

sandrine-boschi-muller

Methionine Sulfoxide Reductase B Displays a High Level of Flexibility

Fanomezana Ranaivoson , Fabrice Neiers , Brice Kauffmann , Sandrine Boschi-Muller , Guy Branlant
Journal of Molecular Biology, 2009, 394 (1), pp.83 - 93. ⟨10.1016/j.jmb.2009.08.073⟩
Article dans une revue hal-01690443v1

A Structural Analysis of the Catalytic Mechanism of Methionine Sulfoxide Reductase A from Neisseria meningitidis

Fanomezana Ranaivoson , Mathias Antoine , Brice Kauffmann , Sandrine Boschi-Muller , André Aubry
Journal of Molecular Biology, 2008, 377 (1), pp.268 - 280. ⟨10.1016/j.jmb.2008.01.021⟩
Article dans une revue hal-01690635v1
Image document

Functional and structural aspects of poplar cytosolic and plastidial type A methionine sulfoxide reductases

Nicolas Rouhier , Brice Kauffmann , Frédérique Tete-Favier , Pasquale Palladino , Pierre Gans
Journal of Biological Chemistry, 2007, 282 (5), pp.3367-3378. ⟨10.1074/jbc.M605007200⟩
Article dans une revue hal-02655515v1

The X-ray structure of the N-terminal domaine of PILB from Neissera meningitidis reveals a thioredoxin-fold

F.M. Ranaivoson , B. Kauffmann , F. Neiers , J. Wu , S. Boschi-Muller
Journal of Molecular Biology, 2006, 358/2, pp.443-454
Article dans une revue hal-00089617v1
Image document

Crystal Structure of Two Ternary Complexes of Phosphorylating Glyceraldehyde-3-phosphate Dehydrogenase from Bacillus stearothermophilus with NAD and d-Glyceraldehyde 3-Phosphate

Claude Didierjean , Catherine Corbier , Mustapha Fatih , Frederique Favier , Sandrine Boschi-Muller
Journal of Biological Chemistry, 2003, 278 (15), pp.12968-12976. ⟨10.1074/jbc.M211040200⟩
Article dans une revue hal-01690824v1

Crystallization and preliminary X-ray diffraction studies of the peptide methionine sulfoxide reductase B domain of Neisseria meningitidis PILB

Brice Kauffmann , Frederique Favier , Alexandre Olry , Sandrine Boschi-Muller , Philippe Carpentier
Acta crystallographica Section D : Structural biology [1993-..], 2002, 58 (9), pp.1467 - 1469. ⟨10.1107/S0907444902010570⟩
Article dans une revue hal-01690844v1

Crystallization and preliminary X-ray diffraction studies of the peptide methionine sulfoxide reductase from Escherichia coli.

F. Tête-Favier , D. Cobessi , G. A. Leonard , S. Azza , F. Talfournier
Acta crystallographica Section D : Structural biology [1993-..], 2000, 56 (Pt 9), pp.1194-7. ⟨10.1107/s0907444903006814⟩
Article dans une revue hal-00151126v1

Crystal structure of the Escherichia coli peptide methionine sulphoxide reductase at 1.9 A resolution.

F. Tête-Favier , D. Cobessi , S. Boschi-Muller , S. Azza , G. Branlant
Structure / Struct Fold Des; Structure (Camb ), 2000, 8 (11), pp.1167-78
Article dans une revue hal-00151127v1

Structure tridimensionnelle d'une méthionine sulfoxyde reductase de classe A en complexe avec un substrat

F.M. Ranaivoson , M. Antoine , S. Boschi-Muller , G. Branlant , A. Aubry
14ème Réunion du Groupe Français des Peptides et des Protéines (GFPP), 2005, Aussois, France
Communication dans un congrès hal-00089642v1