Gabriel MARKOV
CRCN CNRS
3
Documents
Affiliations actuelles
- 542078
Identifiants chercheurs
- gabriel-markov
- 0000-0002-8566-7482
- Google Scholar : https://scholar.google.fr/citations?user=-JiG5QcAAAAJ
- IdRef : 155301837
Présentation
I investigate metabolic pathway evolution, integrating information about the evolution of single enzymes with the distribution of metabolites accross lineages. This led me to develop methods to tackle directly the evolution of pathways at that level of abstraction. I am strongly interested about eukaryotic metabolic pathways for which there is a significant amount of detailed biological knowledge, such as those producing signaling molecules.
Publications
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Asymmetric dimerization in a transcription factor superfamily is promoted by allosteric interactions with DNANucleic Acids Research, 2023, 51 (16), pp.8864-8879. ⟨10.1093/nar/gkad632⟩
Article dans une revue
hal-04234634v1
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A novel nuclear receptor subfamily enlightens the origin of heterodimerizationBMC Biology, 2022, 20 (1), pp.217. ⟨10.1186/s12915-022-01413-0⟩
Article dans une revue
hal-03843774v1
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A structural signature motif enlightens the origin and diversification of nuclear receptorsPLoS Genetics, 2021, 17 (4), pp.e1009492. ⟨10.1371/journal.pgen.1009492⟩
Article dans une revue
hal-03222330v1
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