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Gabriel MARKOV

CRCN CNRS
32
Documents
Affiliations actuelles
  • 542078
Identifiants chercheurs

Présentation

I investigate metabolic pathway evolution, integrating information about the evolution of single enzymes with the distribution of metabolites accross lineages. This led me to develop methods to tackle directly the evolution of pathways at that level of abstraction. I am strongly interested about eukaryotic metabolic pathways for which there is a significant amount of detailed biological knowledge, such as those producing signaling molecules.

Publications

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Inferring and comparing metabolism across heterogeneous sets of annotated genomes using AuCoMe

Arnaud Belcour , Jeanne Got , Méziane Aite , Ludovic Delage , Jonas Collén
Genome Research, 2023, 33, pp.972 - 987. ⟨10.1101/gr.277056.122⟩
Article dans une revue hal-04192851v3
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Asymmetric dimerization in a transcription factor superfamily is promoted by allosteric interactions with DNA

Abdul Kareem Mohideen Patel , Pierre Vilela , Tajith Baba Shaik , Alastair G Mcewen , Isabelle Hazemann
Nucleic Acids Research, 2023, 51 (16), pp.8864-8879. ⟨10.1093/nar/gkad632⟩
Article dans une revue hal-04234634v1
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Aldehyde perception induces specific molecular responses in Laminaria digitata and affects algal consumption by a specialist grazer

Qikun Xing , Léa Cabioch , Antoine Desrut , Gildas Le Corguillé , Sylvie Rousvoal
Plant Journal, In press, ⟨10.1111/tpj.16450⟩
Article dans une revue hal-04197531v1
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Small molecules as products of evolution

Gabriel Markov , Vincent Laudet
Current Biology - CB, 2022, 32 (3), pp.R100-R105. ⟨10.1016/j.cub.2021.12.038⟩
Article dans une revue hal-03937973v1
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Independent Evolution of the MYB Family in Brown Algae

Qiangcheng Zeng , Hanyu Liu , Xiaonan Chu , Yonggang Niu , Caili Wang
Frontiers in Genetics, 2022, 12, ⟨10.3389/fgene.2021.811993⟩
Article dans une revue hal-03938547v1
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A novel nuclear receptor subfamily enlightens the origin of heterodimerization

Brice Beinsteiner , Gabriel V Markov , Maxime Bourguet , Alastair G Mcewen , Stéphane Erb
BMC Biology, 2022, 20 (1), pp.217. ⟨10.1186/s12915-022-01413-0⟩
Article dans une revue hal-03843774v1
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A structural signature motif enlightens the origin and diversification of nuclear receptors

Brice Beinsteiner , Gabriel V Markov , Stéphane Erb , Yassmine Chebaro , Alastair G Mcewen
PLoS Genetics, 2021, 17 (4), pp.e1009492. ⟨10.1371/journal.pgen.1009492⟩
Article dans une revue hal-03222330v1
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Semi-Quantitative Targeted Gas Chromatography-Mass Spectrometry Profiling Supports a Late Side-Chain Reductase Cycloartenol-to-Cholesterol Biosynthesis Pathway in Brown Algae

Jean Girard , Goulven Lanneau , Ludovic Delage , Cédric Leroux , Arnaud Belcour
Frontiers in Plant Science, 2021, 12, pp.1-10. ⟨10.3389/fpls.2021.648426⟩
Article dans une revue hal-03222505v1

Different Early Responses of Laminariales to an Endophytic Infection Provide Insights About Kelp Host Specificity

Qikun Xing , Miriam Bernard , Sylvie Rousvoal , Erwan Corre , Gabriel Markov
Frontiers in Marine Science, 2021, 8, ⟨10.3389/fmars.2021.742469⟩
Article dans une revue hal-03454704v1
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Biological rhythms in the deep-sea hydrothermal mussel Bathymodiolus azoricus

Audrey Mat , Jozée Sarrazin , Gabriel Markov , Vincent Apremont , Christine Dubreuil
Nature Communications, 2020, 11 (1), ⟨10.1038/s41467-020-17284-4⟩
Article dans une revue hal-02907599v1
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The genome of Ectocarpus subulatus – A highly stress-tolerant brown alga

Simon M. Dittami , Erwan Corre , Loraine Brillet-Guéguen , Agnieszka Lipinska , Noé Pontoizeau
Marine Genomics, 2020, 52, pp.100740. ⟨10.1016/j.margen.2020.100740⟩
Article dans une revue hal-02866117v1
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Inferring Biochemical Reactions and Metabolite Structures to Understand Metabolic Pathway Drift

Arnaud Belcour , Jean Girard , Méziane Aite , Ludovic Delage , Camille Trottier
iScience, 2020, 23 (2), pp.100849. ⟨10.1016/j.isci.2020.100849⟩
Article dans une revue hal-01943880v2
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Diversity and evolution of cytochromes P450 in stramenopiles

Linhong Teng , Xiao Fan , David R. Nelson , Wentao Han , Xiao Zhang
Planta, 2019, 249 (3), pp.647-661. ⟨10.1007/s00425-018-3028-1⟩
Article dans une revue hal-02065007v1
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Genome–Scale Metabolic Networks Shed Light on the Carotenoid Biosynthesis Pathway in the Brown Algae Saccharina japonica and Cladosiphon okamuranus

Delphine Nègre , Méziane Aite , Arnaud Belcour , Clémence Frioux , Loraine Brillet-Guéguen
Antioxidants , 2019, 8 (11), pp.564. ⟨10.3390/antiox8110564⟩
Article dans une revue hal-02395080v1
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Hormonally active phytochemicals from macroalgae: a largely untapped source of ligands to deorphanize nuclear receptors in emerging marine animal models

Gabriel V. Markov , Jean Girard , Vincent Laudet , Catherine Leblanc
General and Comparative Endocrinology, 2018, 265, pp.41-45. ⟨10.1016/j.ygcen.2018.06.004⟩
Article dans une revue hal-02393542v1
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Traceability, reproducibility and wiki-exploration for "à-la-carte" reconstructions of genome-scale metabolic models

Méziane Aite , Marie Chevallier , Clémence Frioux , Camille Trottier , Jeanne Got
PLoS Computational Biology, 2018, 14 (5), pp.e1006146. ⟨10.1371/journal.pcbi.1006146⟩
Article dans une revue hal-01807842v1

Linking Genomic and Metabolomic Natural Variation Uncovers Nematode Pheromone Biosynthesis

Jan Falcke , Neelanjan Bose , Alexander Artyukhin , Christian Rödelsperger , Gabriel V. Markov
Cell Chemical Biology, 2018, 25 (6), pp.787-796.e12. ⟨10.1016/j.chembiol.2018.04.004⟩
Article dans une revue hal-03941058v1
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NR3E receptors in cnidarians: A new family of steroid receptor relatives extends the possible mechanisms for ligand binding

Konstantin Khalturin , Isabelle M.L. Billas , Yassmine Chebaro , Adam M. Reitzel , Ann M. Tarrant
Journal of Steroid Biochemistry and Molecular Biology, 2018, 184, pp.11-19. ⟨10.1016/j.jsbmb.2018.06.014⟩
Article dans une revue hal-02017750v1
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Origin of an ancient hormone/receptor couple revealed by resurrection of an ancestral estrogen

Gabriel Markov , Juliana Gutierrez-Mazariegos , Delphine Pitrat , Isabelle M. L. Billas , François Bonneton
Science Advances , 2017, 3 (3), pp.e1601778. ⟨10.1126/sciadv.1601778⟩
Article dans une revue hal-01693173v1
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Functional Conservation and Divergence ofdaf-22Paralogs inPristionchus pacificusDauer Development

Gabriel V. Markov , Jan M Meyer , Oishika Panda , Alexander B Artyukhin , Marc Claaßen
Molecular Biology and Evolution, 2016, 33 (10), pp.2506 - 2514. ⟨10.1093/molbev/msw090⟩
Article dans une revue hal-04460142v1
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On the origin and evolutionary history of NANOG

Pierluigi Scerbo , Gabriel V Markov , Céline Vivien , Laurent Kodjabachian , Barbara Demeneix
PLoS ONE, 2014, 9 (1), pp.e85104. ⟨10.1371/journal.pone.0085104⟩
Article dans une revue hal-01111124v1
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Ventx factors function as Nanog-like guardians of developmental potential in Xenopus

Pierluigi Scerbo , Fabrice Girardot , Céline Vivien , Gabriel V Markov , Guillaume Luxardi
PLoS ONE, 2012, 7 (5), pp.e36855. ⟨10.1371/journal.pone.0036855⟩
Article dans une revue hal-00843463v1

Origin and evolution of the ligand-binding ability of nuclear receptors

Gabriel Markov , Vincent Laudet
Molecular and Cellular Endocrinology, 2011, 334 (1-2), pp.21 - 30. ⟨10.1016/j.mce.2010.10.017⟩
Article dans une revue hal-02648059v1

Evolution of Nuclear Retinoic Acid Receptor Alpha (RAR alpha) Phosphorylation Sites. Serine Gain Provides Fine-Tuned Regulation

Eric Samarut , Ismail Amal , Gabriel Markov , Roland Stote , Annick Dejaegere
Molecular Biology and Evolution, 2011, 28 (7), pp.2125 - 2137. ⟨10.1093/molbev/msr035⟩
Article dans une revue hal-02645447v1

Independent elaboration of steroid hormone signaling pathways in metazoans

Gabriel V Markov , Raquel Tavares , Chantal Dauphin-Villemant , Barbara A. Demeneix , Michael E. Baker
Proceedings of the National Academy of Sciences of the United States of America, 2009, 106 (29), pp.11913-11918. ⟨10.1073/pnas.0812138106⟩
Article dans une revue hal-02666864v1
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The evolution of the ligand/receptor couple: a long road from comparative endocrinology to comparative genomics

Gabriel V Markov , Mathilde Paris , Stephanie Bertrand , Vincent Laudet
Molecular and Cellular Endocrinology, 2008, 293 (1-2), pp.5. ⟨10.1016/j.mce.2008.06.011⟩
Article dans une revue hal-00532041v1

The "street light syndrome", or how protein taxonomy can bias experimental manipulations

Gabriel Markov , Guillaume Lecointre , Barbara Demeneix , Vincent Laudet
BioEssays, 2008, 30 (4), pp.349-357. ⟨10.1002/bies.20730⟩
Article dans une revue hal-02662543v1

Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita

Pierre Abad , Jerome Gouzy , Jean-Marc Aury , Philippe Castagnone-Sereno , Etienne Danchin
Nature Biotechnology, 2008, 26 (8), pp.909-915. ⟨10.1038/nbt.1482⟩
Article dans une revue hal-01189285v1

Evolution of nuclear receptors in insects

François Bonneton , Arnaud Chaumot , T. Iwema , I. Billas , D. Moras
18th International Ecdysone Workshop 2010, Jul 2010, Ceske Budejovice, Czech Republic. pp.1
Communication dans un congrès hal-02593438v1
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Evolution of Hormonal Mechanisms

Vincent Laudet , Gabriel V. Markov
Encyclopedia of Endocrine Diseases, Second Edition, 2018, 978-0-12-812200-6. ⟨10.1016/B978-0-12-812199-3.64198-1⟩
Chapitre d'ouvrage hal-03941018v1
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Evolution of Steroid Signaling in Metazoans

Gabriel Markov
Agricultural sciences. Ecole normale supérieure de lyon - ENS LYON, 2011. English. ⟨NNT : 2011ENSL0634⟩
Thèse tel-01373637v1