Gabriel MARKOV

37
Documents
Affiliation actuelle
  • Laboratoire de Biologie Intégrative des Modèles Marins (LBI2M)

Présentation

I investigate metabolic pathway evolution, integrating information about the evolution of single enzymes with the distribution of metabolites accross lineages. This led me to develop methods to tackle directly the evolution of pathways at that level of abstraction. I am strongly interested about eukaryotic metabolic pathways for which there is a significant amount of detailed biological knowledge, such as those producing signaling molecules.

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Publications

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Plant and algal lipidomes: Analysis, composition, and their societal significance

Juliette Jouhet , Eliana Alves , Yohann Boutté , Sylvain Darnet , Frédéric Domergue et al.
Progress in Lipid Research, 2024, 96, pp.101290. ⟨10.1016/j.plipres.2024.101290⟩
Article dans une revue hal-04673335 v1
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Evolutionary genomics of the emergence of brown algae as key components of coastal ecosystems

France Denoeud , Olivier Godfroy , Corinne Cruaud , Svenja Heesch , Zofia Nehr et al.
Cell, 2024, 187 (24), pp.6943-6965. ⟨10.1016/j.cell.2024.10.049⟩
Article dans une revue hal-04794231 v1
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A review on the chemical ecology of the Fucaceae holobionts: from fundamental knowledge to applications

Coralie Rousseau , Gautier Demoulinger , Sylvie Rousvoal , Delphine Champeval , Maurane Dolly et al.
Comptes Rendus. Chimie, 2024, 26 (S2), pp.1-25. ⟨10.5802/crchim.271⟩
Article dans une revue hal-04740350 v1
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Empirical evidence for metabolic drift in plant and algal lipid biosynthesis pathways

Maëlle Zonnequin , Arnaud Belcour , Ludovic Delage , Anne Siegel , Samuel Blanquart et al.
Frontiers in Plant Science, 2024, 15, pp.1339132. ⟨10.3389/fpls.2024.1339132⟩
Article dans une revue (article de synthèse) hal-04473577 v1
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Asymmetric dimerization in a transcription factor superfamily is promoted by allosteric interactions with DNA

Abdul Kareem Mohideen Patel , Pierre Vilela , Tajith Baba Shaik , Alastair G Mcewen , Isabelle Hazemann et al.
Nucleic Acids Research, 2023, 51 (16), pp.8864-8879. ⟨10.1093/nar/gkad632⟩
Article dans une revue hal-04234634 v1
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Aldehyde perception induces specific molecular responses in Laminaria digitata and affects algal consumption by a specialist grazer

Qikun Xing , Léa Cabioch , Antoine Desrut , Gildas Le Corguillé , Sylvie Rousvoal et al.
The Plant Journal, In press, ⟨10.1111/tpj.16450⟩
Article dans une revue hal-04197531 v1
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Inferring and comparing metabolism across heterogeneous sets of annotated genomes using AuCoMe

Arnaud Belcour , Jeanne Got , Méziane Aite , Ludovic Delage , Jonas Collén et al.
Genome Research, 2023, 33, pp.972 - 987. ⟨10.1101/gr.277056.122⟩
Article dans une revue hal-04192851 v3
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A novel nuclear receptor subfamily enlightens the origin of heterodimerization

Brice Beinsteiner , Gabriel V Markov , Maxime Bourguet , Alastair G Mcewen , Stéphane Erb et al.
BMC Biology, 2022, 20 (1), pp.217. ⟨10.1186/s12915-022-01413-0⟩
Article dans une revue hal-03843774 v1
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Independent Evolution of the MYB Family in Brown Algae

Qiangcheng Zeng , Hanyu Liu , Xiaonan Chu , Yonggang Niu , Caili Wang et al.
Frontiers in Genetics, 2022, 12, ⟨10.3389/fgene.2021.811993⟩
Article dans une revue hal-03938547 v1
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Small molecules as products of evolution

Gabriel Markov , Vincent Laudet
Current Biology, 2022, 32 (3), pp.R100-R105. ⟨10.1016/j.cub.2021.12.038⟩
Article dans une revue hal-03937973 v1
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A structural signature motif enlightens the origin and diversification of nuclear receptors

Brice Beinsteiner , Gabriel V Markov , Stéphane Erb , Yassmine Chebaro , Alastair G Mcewen et al.
PLoS Genetics, 2021, 17 (4), pp.e1009492. ⟨10.1371/journal.pgen.1009492⟩
Article dans une revue hal-03222330 v1

Different Early Responses of Laminariales to an Endophytic Infection Provide Insights About Kelp Host Specificity

Qikun Xing , Miriam Bernard , Sylvie Rousvoal , Erwan Corre , Gabriel Markov et al.
Frontiers in Marine Science, 2021, 8, ⟨10.3389/fmars.2021.742469⟩
Article dans une revue hal-03454704 v1
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Semi-Quantitative Targeted Gas Chromatography-Mass Spectrometry Profiling Supports a Late Side-Chain Reductase Cycloartenol-to-Cholesterol Biosynthesis Pathway in Brown Algae

Jean Girard , Goulven Lanneau , Ludovic Delage , Cédric Leroux , Arnaud Belcour et al.
Frontiers in Plant Science, 2021, 12, pp.1-10. ⟨10.3389/fpls.2021.648426⟩
Article dans une revue hal-03222505 v1
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Biological rhythms in the deep-sea hydrothermal mussel Bathymodiolus azoricus

Audrey Mat , Jozée Sarrazin , Gabriel Markov , Vincent Apremont , Christine Dubreuil et al.
Nature Communications, 2020, 11 (1), ⟨10.1038/s41467-020-17284-4⟩
Article dans une revue hal-02907599 v1
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The genome of Ectocarpus subulatus – A highly stress-tolerant brown alga

Simon M. Dittami , Erwan Corre , Loraine Brillet-Guéguen , Agnieszka Lipinska , Noé Pontoizeau et al.
Marine Genomics, 2020, 52, pp.100740. ⟨10.1016/j.margen.2020.100740⟩
Article dans une revue hal-02866117 v1
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Inferring Biochemical Reactions and Metabolite Structures to Understand Metabolic Pathway Drift

Arnaud Belcour , Jean Girard , Méziane Aite , Ludovic Delage , Camille Trottier et al.
iScience, 2020, 23 (2), pp.100849. ⟨10.1016/j.isci.2020.100849⟩
Article dans une revue hal-01943880 v2
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Genome–Scale Metabolic Networks Shed Light on the Carotenoid Biosynthesis Pathway in the Brown Algae Saccharina japonica and Cladosiphon okamuranus

Delphine Nègre , Méziane Aite , Arnaud Belcour , Clémence Frioux , Loraine Brillet-Guéguen et al.
Antioxidants , 2019, 8 (11), pp.564. ⟨10.3390/antiox8110564⟩
Article dans une revue hal-02395080 v1
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Diversity and evolution of cytochromes P450 in stramenopiles

Linhong Teng , Xiao Fan , David R. Nelson , Wentao Han , Xiao Zhang et al.
Planta, 2019, 249 (3), pp.647-661. ⟨10.1007/s00425-018-3028-1⟩
Article dans une revue hal-02065007 v1
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NR3E receptors in cnidarians: A new family of steroid receptor relatives extends the possible mechanisms for ligand binding

Konstantin Khalturin , Isabelle M.L. Billas , Yassmine Chebaro , Adam M. Reitzel , Ann M. Tarrant et al.
Journal of Steroid Biochemistry and Molecular Biology, 2018, 184, pp.11-19. ⟨10.1016/j.jsbmb.2018.06.014⟩
Article dans une revue hal-02017750 v1
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Traceability, reproducibility and wiki-exploration for "à-la-carte" reconstructions of genome-scale metabolic models

Méziane Aite , Marie Chevallier , Clémence Frioux , Camille Trottier , Jeanne Got et al.
PLoS Computational Biology, 2018, 14 (5), pp.e1006146. ⟨10.1371/journal.pcbi.1006146⟩
Article dans une revue hal-01807842 v1

Linking Genomic and Metabolomic Natural Variation Uncovers Nematode Pheromone Biosynthesis

Jan Falcke , Neelanjan Bose , Alexander Artyukhin , Christian Rödelsperger , Gabriel V. Markov et al.
Cell Chemical Biology, 2018, 25 (6), pp.787-796.e12. ⟨10.1016/j.chembiol.2018.04.004⟩
Article dans une revue hal-03941058 v1
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Hormonally active phytochemicals from macroalgae: a largely untapped source of ligands to deorphanize nuclear receptors in emerging marine animal models

Gabriel V. Markov , Jean Girard , Vincent Laudet , Catherine Leblanc
General and Comparative Endocrinology, 2018, 265, pp.41-45. ⟨10.1016/j.ygcen.2018.06.004⟩
Article dans une revue hal-02393542 v1
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Origin of an ancient hormone/receptor couple revealed by resurrection of an ancestral estrogen

Gabriel Markov , Juliana Gutierrez-Mazariegos , Delphine Pitrat , Isabelle M. L. Billas , François Bonneton et al.
Science Advances , 2017, 3 (3), pp.e1601778. ⟨10.1126/sciadv.1601778⟩
Article dans une revue hal-01693173 v1
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Functional Conservation and Divergence of<i>daf-22</i>Paralogs in<i>Pristionchus pacificus</i>Dauer Development

Gabriel V. Markov , Jan M Meyer , Oishika Panda , Alexander B Artyukhin , Marc Claaßen et al.
Molecular Biology and Evolution, 2016, 33 (10), pp.2506 - 2514. ⟨10.1093/molbev/msw090⟩
Article dans une revue hal-04460142 v1
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On the origin and evolutionary history of NANOG

Pierluigi Scerbo , Gabriel V Markov , Céline Vivien , Laurent Kodjabachian , Barbara Demeneix et al.
PLoS ONE, 2014, 9 (1), pp.e85104. ⟨10.1371/journal.pone.0085104⟩
Article dans une revue hal-01111124 v1
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Ventx factors function as Nanog-like guardians of developmental potential in Xenopus

Pierluigi Scerbo , Fabrice Girardot , Céline Vivien , Gabriel V Markov , Guillaume Luxardi et al.
PLoS ONE, 2012, 7 (5), pp.e36855. ⟨10.1371/journal.pone.0036855⟩
Article dans une revue hal-00843463 v1

Origin and evolution of the ligand-binding ability of nuclear receptors

Gabriel Markov , Vincent Laudet
Molecular and Cellular Endocrinology, 2011, 334 (1-2), pp.21 - 30. ⟨10.1016/j.mce.2010.10.017⟩
Article dans une revue istex hal-02648059 v1

Evolution of Nuclear Retinoic Acid Receptor Alpha (RAR alpha) Phosphorylation Sites. Serine Gain Provides Fine-Tuned Regulation

Eric Samarut , Ismail Amal , Gabriel Markov , Roland Stote , Annick Dejaegere et al.
Molecular Biology and Evolution, 2011, 28 (7), pp.2125 - 2137. ⟨10.1093/molbev/msr035⟩
Article dans une revue hal-02645447 v1

Independent elaboration of steroid hormone signaling pathways in metazoans

Gabriel V Markov , Raquel Tavares , Chantal Dauphin-Villemant , Barbara A. Demeneix , Michael E. Baker et al.
Proceedings of the National Academy of Sciences of the United States of America, 2009, 106 (29), pp.11913-11918. ⟨10.1073/pnas.0812138106⟩
Article dans une revue hal-02666864 v1

Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita

Pierre Abad , Jerome Gouzy , Jean-Marc Aury , Philippe Castagnone-Sereno , Etienne Danchin et al.
Nature Biotechnology, 2008, 26 (8), pp.909-915. ⟨10.1038/nbt.1482⟩
Article dans une revue hal-01189285 v1
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The evolution of the ligand/receptor couple: a long road from comparative endocrinology to comparative genomics

Gabriel V Markov , Mathilde Paris , Stephanie Bertrand , Vincent Laudet
Molecular and Cellular Endocrinology, 2008, 293 (1-2), pp.5. ⟨10.1016/j.mce.2008.06.011⟩
Article dans une revue hal-00532041 v1

The "street light syndrome", or how protein taxonomy can bias experimental manipulations

Gabriel Markov , Guillaume Lecointre , Barbara Demeneix , Vincent Laudet
BioEssays, 2008, 30 (4), pp.349-357. ⟨10.1002/bies.20730⟩
Article dans une revue istex hal-02662543 v1

Evolution of nuclear receptors in insects

François Bonneton , Arnaud Chaumot , T. Iwema , I. Billas , D. Moras et al.
18th International Ecdysone Workshop 2010, Jul 2010, Ceske Budejovice, Czech Republic. pp.1
Communication dans un congrès hal-02593438 v1
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Evolution of Hormonal Mechanisms

Vincent Laudet , Gabriel V. Markov
Encyclopedia of Endocrine Diseases, Second Edition, 2018, 978-0-12-812200-6. ⟨10.1016/B978-0-12-812199-3.64198-1⟩
Chapitre d'ouvrage hal-03941018 v1
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Evolution of Steroid Signaling in Metazoans

Gabriel Markov
Agricultural sciences. Ecole normale supérieure de lyon - ENS LYON, 2011. English. ⟨NNT : 2011ENSL0634⟩
Thèse tel-01373637 v1