Geanncarlo Lugo-Villarino

92 %
Libre accès
61
Documents
Affiliations actuelles
  • Institut de pharmacologie et de biologie structurale (IPBS)
  • Université Toulouse III - Paul Sabatier (UT3)

Publications

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Publications

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HIV-1 Tat favors the multiplication of Mycobacterium tuberculosis and Toxoplasma by inhibiting clathrin-mediated endocytosis and autophagy

Aurélie Rivault , Audrey Bernut , Myriam Ben-Neji , Magali Abrantes , Maxime Jansen et al.

PLoS Pathogens, 2025, 21 (9), pp.e1013183. ⟨10.1371/journal.ppat.1013183⟩

Article dans une revue hal-05262587v1
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Druggable redox pathways against Mycobacterium abscessus in cystic fibrosis patient-derived airway organoids

Stephen Adonai Leon-Icaza , Salimata Bagayoko , Romain Vergé , Nino Iakobachvili , Chloé Ferrand et al.

PLoS Pathogens, 2023, 19 (8), pp.e1011559. ⟨10.1371/journal.ppat.1011559⟩

Article dans une revue hal-04197558v1
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Mycobacteria–host interactions in human bronchiolar airway organoids

Nino Iakobachvili , Stephen Adonai Leon‐icaza , Kèvin Knoops , Norman Sachs , Serge Mazères et al.

Molecular Microbiology, 2022, 117 (3), pp.682-692. ⟨10.1111/mmi.14824⟩

Article dans une revue hal-03856942v1
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Dysregulation of the IFN-I signaling pathway by Mycobacterium tuberculosis leads to exacerbation of HIV-1 infection of macrophages

Maeva Dupont , Thien-Phong Vu Manh , Karine Pingris , Shanti Souriant , Tomàs Velez et al.

Journal of Leukocyte Biology, 2022, 112 (5), pp.1329-1342. ⟨10.1002/JLB.4MA0422-730R⟩

Article dans une revue hal-04738082v1
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Increased frequency of CD14$^+$HLA-DR<sup>-/low</sup> cells in type 2 diabetes patients with poor glycemic control

M.A. Valtierra-Alvarado , J.E. Castañeda-Delgado , Geanncarlo Lugo-Villarino , F. Dueñas-Arteaga , B. Rivas-Santiago et al.

Human Immunology, 2022, 83 (11), pp.789-795. ⟨10.1016/j.humimm.2022.08.011⟩

Article dans une revue hal-04738359v1
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Impact of type 2 diabetes on the capacity of human macrophages infected with Mycobacterium tuberculosis to modulate monocyte differentiation through a bystander effect

Monica Alejandra Valtierra‐alvarado , Geanncarlo Lugo-Villarino , Fátima Dueñas-Arteaga , Beatriz Elena González-Contreras , Anahí Lugo-Sánchez et al.

Immunology and Cell Biology, 2021, 99 (10), pp.1026-1039. ⟨10.1111/imcb.12497⟩

Article dans une revue hal-04737989v1

A Pulmonary Lactobacillus murinus Strain Induces Th17 and RORγt + Regulatory T Cells and Reduces Lung Inflammation in Tuberculosis

Lucie Bernard-Raichon , André Colom , Sarah C Monard , Amine Namouchi , Margaux Cescato et al.

Journal of Immunology, 2021, 207 (7), pp.1857-1870. ⟨10.4049/jimmunol.2001044⟩

Article dans une revue hal-03367614v1
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Dysbiosis, malnutrition and enhanced gut-lung axis contribute to age-related respiratory diseases

Vinciane Saint-Criq , Geanncarlo Lugo-Villarino , Muriel Thomas

Ageing Research Reviews - ARR, 2021, 66, pp.101235. ⟨10.1016/j.arr.2020.101235⟩

Article dans une revue (article de synthèse) hal-03129383v1
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Dissemination of Mycobacterium tuberculosis is associated to a SIGLEC1 null variant that limits antigen exchange via trafficking extracellular vesicles

Susana Benet , Cristina Gálvez , Francis Drobniewski , Irina Kontsevaya , Lilibeth Arias et al.

Journal of Extracellular Vesicles, 2021, 10 (3), pp.17. ⟨10.1002/jev2.12046⟩

Article dans une revue hal-04737910v1
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Host phospholipid peroxidation fuels ExoU-dependent cell necrosis and supports $Pseudomonas\ aeruginosa$-driven pathology

Salimata Bagayoko , Stephen Adonai Leon-Icaza , Miriam Pinilla , Audrey Hessel , Karin Santoni et al.

PLoS Pathogens, 2021, 17 (9), pp.e1009927. ⟨10.1371/journal.ppat.1009927⟩

Article dans une revue hal-03355818v1
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Host-Derived Lipids from Tuberculous Pleurisy Impair Macrophage Microbicidal-Associated Metabolic Activity

José Luis Marín Franco , Melanie Genoula , Dan Corral , Gabriel Duette , Malena Ferreyra et al.

Cell Reports, 2020, 33 (13), pp.108547. ⟨10.1016/j.celrep.2020.108547⟩

Article dans une revue hal-03450535v2
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Tuberculosis-associated IFN-I induces Siglec-1 on tunneling nanotubes and favors HIV-1 spread in macrophages

Maeva Dupont , Shanti Souriant , Luciana Balboa , Thien-Phong Vu Manh , Karine Pingris et al.

eLife, 2020, 9, ⟨10.7554/eLife.52535⟩

Article dans une revue hal-02995702v1
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Le récepteur Siglec-1/CD169 sur les macrophages : un catalyseur de la synergie infectieuse entre Mycobacterium tuberculosis et le VIH-1

M Dupont , Geanncarlo Lugo-Villarino , C. Vérollet

Médecine/Sciences, 2020, 36 (10), pp.855-858. ⟨10.1051/medsci/2020155⟩

Article dans une revue hal-03017395v1
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Fatty acid oxidation of alternatively activated macrophages prevents foam cell formation, but Mycobacterium tuberculosis counteracts this process via HIF-1α activation

Melanie Genoula , José Luis Marín Franco , Mariano Maio , Belén Dolotowicz , Malena Ferreyra et al.

PLoS Pathogens, 2020, 16 (10), pp.e1008929. ⟨10.1371/journal.ppat.1008929⟩

Article dans une revue hal-03017388v1
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Type 2 diabetes mellitus metabolic control correlates with the phenotype of human monocytes and monocyte-derived macrophages

Monica Alejandra Valtierra-Alvarado , Julio Enrique Castañeda-Delgado , Sandra Iveth Ramírez-Talavera , Geanncarlo Lugo-Villarino , Fátima Dueñas-Arteaga et al.

Journal of Diabetes and its Complications, 2020, 34 (11), pp.107708. ⟨10.1016/j.jdiacomp.2020.107708⟩

Article dans une revue hal-03017379v1
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Editorial: The Mononuclear Phagocyte System in Infectious Disease

Geanncarlo Lugo-Villarino , Céline Cougoule , Etienne Meunier , Yoann Rombouts , Christel Vérollet et al.

Frontiers in Immunology, 2019, 10, pp.1443. ⟨10.3389/fimmu.2019.01443⟩

Article dans une revue hal-02347777v1
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Tuberculosis Exacerbates HIV-1 infection through IL-10/STAT3-Dependent Tunneling Nanotube Formation in Macrophages

Shanti Souriant , Luciana Balboa , Maeva Dupont , Karine Pingris , Denise Kviatcovsky et al.

Cell Reports, 2019, 26 (13), pp.3586-3599.e7. ⟨10.1016/j.celrep.2019.02.091⟩

Article dans une revue hal-03034321v2
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Variability in the virulence of specific Mycobacterium tuberculosis clinical isolates alters the capacity of human dendritic cells to signal for T cells

Ana Gabriela Ramos-Martinez , Monica Alejandra Valtierra-Alvarado , Mariana Haydee Garcia-Hernandez , Rogelio Hernandez-Pando , Julio Enrique Castañeda-Delgado et al.

Memórias do Instituto Oswaldo Cruz, 2019, 114, pp.e190102. ⟨10.1590/0074-02760190102⟩

Article dans une revue hal-02346891v1
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Les nanotubes membranaires des macrophages infectés par le VIH-1

Shanti Souriant , Maeva Dupont , Olivier Neyrolles , Isabelle Maridonneau-Parini , Geanncarlo Lugo-Villarino et al.

Médecine/Sciences, 2019, 35 (11), pp.825-827. ⟨10.1051/medsci/2019159⟩

Article dans une revue hal-03017306v1
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The C-Type Lectin Receptor DC-SIGN Has an Anti-Inflammatory Role in Human M(IL-4) Macrophages in Response to Mycobacterium tuberculosis

Geanncarlo Lugo-Villarino , Anthony Troegeler , Luciana Balboa , Claire Lastrucci , Carine Duval et al.

Frontiers in Immunology, 2018, 9, ⟨10.3389/fimmu.2018.01123⟩

Article dans une revue hal-02348476v1

Formation of Foamy Macrophages by Tuberculous Pleural Effusions Is Triggered by the Interleukin-10/Signal Transducer and Activator of Transcription 3 Axis through ACAT Upregulation

Melanie Genoula , José Luis Marín Franco , Maeva Dupont , Denise Kviatcovsky , Ayelén Milillo et al.

Frontiers in Immunology, 2018, 9, ⟨10.3389/fimmu.2018.00459⟩

Article dans une revue hal-04958873v1
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Formation of Foamy Macrophages by Tuberculous Pleural Effusions Is Triggered by the Interleukin-10/Signal Transducer and Activator of Transcription 3 Axis through ACAT Upregulation

Melanie Genoula , José Luis Marín Franco , Maeva Dupont , Denise Kviatcovsky , Ayelén Milillo et al.

Frontiers in Immunology, 2018, 9, ⟨10.3389/fimmu.2018.00459⟩

Article dans une revue hal-02348491v1
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Tunneling Nanotubes: Intimate Communication between Myeloid Cells

Maeva Dupont , Shanti Souriant , Geanncarlo Lugo-Villarino , Isabelle Maridonneau-Parini , Christel Vérollet

Frontiers in Immunology, 2018, 9, ⟨10.3389/fimmu.2018.00043⟩

Article dans une revue hal-02348503v1

Tunneling Nanotubes: Intimate Communication between Myeloid Cells

Maeva Dupont , Shanti Souriant , Geanncarlo Lugo-Villarino , Isabelle Maridonneau-Parini , Christel Vérollet

Frontiers in Immunology, 2018, 9, ⟨10.3389/fimmu.2018.00043⟩

Article dans une revue hal-04958698v1

Type-2 diabetes alters the basal phenotype of human macrophages and diminishes their capacity to respond, internalise, and control Mycobacterium tuberculosis

Nallely Lopez-Lopez , Ana Gabriela Ramos Martinez , Mariana Haydee Garcia-Hernandez , Rogelio Hernandez-Pando , Julio Enrique Castañeda-Delgado et al.

Memórias do Instituto Oswaldo Cruz, 2018, 113 (4), ⟨10.1590/0074-02760170326⟩

Article dans une revue hal-02348497v1
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Podosomes, But Not the Maturation Status, Determine the Protease-Dependent 3D Migration in Human Dendritic Cells

Céline Cougoule , Claire Lastrucci , Romain Guiet , Rémi Mascarau , Etienne Meunier et al.

Frontiers in Immunology, 2018, 9, ⟨10.3389/fimmu.2018.00846⟩

Article dans une revue hal-02348486v1

The role of the lung microbiota and the gut-lung axis in respiratory infectious diseases

Alexia Dumas , Lucie Bernard , Yannick Poquet , Geanncarlo Lugo-Villarino , Olivier Neyrolles

Cellular Microbiology, 2018, 20 (12), pp.e12966. ⟨10.1111/cmi.12966⟩

Article dans une revue hal-02346963v1
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C-type lectin receptor DCIR modulates immunity to tuberculosis by sustaining type I interferon signaling in dendritic cells

Anthony Troegeler , Ingrid Mercier , Céline Cougoule , Danilo Pietretti , André Colom et al.

Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (4), pp.E540-E549. ⟨10.1073/pnas.1613254114⟩

Article dans une revue hal-02348507v1

Role of Cathepsins in Mycobacterium tuberculosis Survival in Human Macrophages

David Pires , Joana Marques , João Palma Pombo , Nuno Carmo , Paulo Bettencourt et al.

Scientific Reports, 2016, 6 (1), ⟨10.1038/srep32247⟩

Article dans une revue hal-02348513v1

Tuberculosis is associated with expansion of a motile, permissive and immunomodulatory CD16+ monocyte population via the IL-10/STAT3 axis

Claire Lastrucci , Alan Bénard , Luciana Balboa , Karine Pingris , Shanti Souriant et al.

Cell Research, 2015, 25 (12), pp.1333-1351. ⟨10.1038/cr.2015.123⟩

Article dans une revue hal-02348517v1

Pyroptosis of resident macrophages differentially orchestrates inflammatory responses to Staphylococcus aureus in resistant and susceptible mice

Solène Accarias , Geanncarlo Lugo-Villarino , Gilles Foucras , Olivier Neyrolles , Séverine Boullier et al.

European Journal of Immunology, 2015, 45 (3), pp.794-806. ⟨10.1002/eji.201445098⟩

Article dans une revue hal-02348547v1
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Collectin CL-LK Is a Novel Soluble Pattern Recognition Receptor for Mycobacterium tuberculosis

Anthony Troegeler , Geanncarlo Lugo-Villarino , Søren Hansen , Voahangy Rasolofo , Maiken Lumby Henriksen et al.

PLoS ONE, 2015, 10 (7), pp.e0132692. ⟨10.1371/journal.pone.0132692⟩

Article dans une revue hal-02348524v1

SIGN ing a symbiotic treaty with gut microbiota

Geanncarlo Lugo-Villarino , Olivier Neyrolles

EMBO Journal, 2015, 34 (7), pp.829-831. ⟨10.15252/embj.201591266⟩

Article dans une revue hal-02348533v1

Diverging biological roles among human monocyte subsets in the context of tuberculosis infection

Luciana Balboa , Jorge Barrios-Payán , Erika González-Domínguez , Claire Lastrucci , Geanncarlo Lugo-Villarino et al.

Clinical Science, 2015, 129 (4), pp.319-330. ⟨10.1042/CS20150021⟩

Article dans une revue hal-02348528v1

An efficient siRNA-mediated gene silencing in primary human monocytes, dendritic cells and macrophages

Anthony Troegeler , Claire Lastrucci , Carine Duval , Antoine Tanne , Céline Cougoule et al.

Immunology and Cell Biology, 2014, 92 (8), pp.699-708. ⟨10.1038/icb.2014.39⟩

Article dans une revue hal-02348566v1

Of Clots and Granulomas: Platelets are New Players in Immunity to Tuberculosis

G. Lugo-Villarino , O. Neyrolles

Journal of Infectious Diseases, 2014, 210 (11), pp.1687-1690. ⟨10.1093/infdis/jiu356⟩

Article dans une revue hal-02348560v1

A genomic portrait of the genetic architecture and regulatory impact of microRNA expression in response to infection

K. Siddle , M. Deschamps , L. Tailleux , Y. Nédelec , J. Pothlichet et al.

Genome Research, 2014, 24 (5), pp.850-859. ⟨10.1101/gr.161471.113⟩

Article dans une revue hal-02348571v1

Manipulation of the Mononuclear Phagocyte System by Mycobacterium tuberculosis

G. Lugo-Villarino , O. Neyrolles

Cold Spring Harbor Perspectives in Medicine, 2014, 4 (11), pp.a018549-a018549. ⟨10.1101/cshperspect.a018549⟩

Article dans une revue hal-02348555v1
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Playing hide-and-seek with host macrophages through the use of mycobacterial cell envelope phthiocerol dimycocerosates and phenolic glycolipids

Ainhoa Arbues , Geancarlo Lugo-Villarino , Olivier Neyrolles , Christophe Guilhot , Catherine Astarie-Dequeker

Frontiers in Cellular and Infection Microbiology, 2014, 4, pp.173. ⟨10.3389/fcimb.2014.00173⟩

Article dans une revue hal-02325951v1

Mycobacterium tuberculosis nitrogen assimilation and host colonization require aspartate

Alexandre Gouzy , Gerald Larrouy-Maumus , Ting-Di Wu , Antonio Peixoto , Florence Levillain et al.

Nature Chemical Biology, 2013, 9 (11), pp.674-676. ⟨10.1038/nchembio.1355⟩

Article dans une revue hal-02348577v1
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Emerging Trends in the Formation and Function of Tuberculosis Granulomas

Geanncarlo Lugo-Villarino , D. Hudrisier , A. Bénard , Olivier Neyrolles

Frontiers in Immunology, 2013, 3, pp.405. ⟨10.3389/fimmu.2012.00405⟩

Article dans une revue hal-02348606v1

Actin-binding protein regulation by microRNAs as a novel microbial strategy to modulate phagocytosis by host cells: the case of N-Wasp and miR-142-3p

Paulo Bettencourt , Sabrina Marion , David Pires , Leonor Santos , Claire Lastrucci et al.

Frontiers in Cellular and Infection Microbiology, 2013, 3, ⟨10.3389/fcimb.2013.00019⟩

Article dans une revue hal-02348587v1

Dressed not to kill: CD16 + monocytes impair immune defence against tuberculosis

Geanncarlo Lugo-Villarino , Olivier Neyrolles

European Journal of Immunology, 2013, 43 (2), pp.327-330. ⟨10.1002/eji.201243256⟩

Article dans une revue hal-02348597v1

The C-type Lectin Receptors Dectin-1, MR, and SIGNR3 Contribute Both Positively and Negatively to the Macrophage Response to Leishmania infantum

Lise Lefèvre , Geanncarlo Lugo-Villarino , Etienne Meunier , Alexis Valentin , David Olagnier et al.

Immunity, 2013, 38 (5), pp.1038-1049. ⟨10.1016/j.immuni.2013.04.010⟩

Article dans une revue hal-02348593v1

Metallobiology of host–pathogen interactions: an intoxicating new insight

Hélène Botella , Gustavo Stadthagen , Geanncarlo Lugo-Villarino , Chantal de Chastellier , Olivier Neyrolles

Trends in Microbiology, 2012, 20 (3), pp.106-112. ⟨10.1016/j.tim.2012.01.005⟩

Article dans une revue istex hal-02348611v1

Macrophage polarization: convergence point targeted by Mycobacterium tuberculosis and HIV

Geanncarlo Lugo-Villarino

Frontiers in Immunology, 2011, 2, ⟨10.3389/fimmu.2011.00043⟩

Article dans une revue hal-02348631v1

Mycobacterial p(1)-type ATPases mediate resistance to zinc poisoning in human macrophages.

Hélène Botella , Pascale Peyron , Florence Levillain , Renaud Poincloux , Yannick Poquet et al.

Cell Host and Microbe, 2011, 10 (3), pp.248-59. ⟨10.1016/j.chom.2011.08.006⟩

Article dans une revue hal-00674577v1
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C-type lectins with a sweet spot for Mycobacterium tuberculosis

G. Lugo-Villarino , D. Hudrisier , A. Tanne , Olivier Neyrolles

European Journal of Microbiology and Immunology, 2011, 1 (1), pp.25-40. ⟨10.1556/EuJMI.1.2011.1.6⟩

Article dans une revue hal-02348626v1

Editorial: How to play tag? DC-SIGN shows the way!

G. Lugo-Villarino , O. Neyrolles

Journal of Leukocyte Biology, 2011, 89 (3), pp.321-323. ⟨10.1189/jlb.1010547⟩

Article dans une revue hal-02348621v1

Eosinophils in the zebrafish: prospective isolation, characterization, and eosinophilia induction by helminth determinants

Keir Balla , Geanncarlo Lugo-Villarino , Jan Spitsbergen , David Stachura , Yan Hu et al.

Blood, 2010, 116 (19), pp.3944-3954. ⟨10.1182/blood-2010-03-267419⟩

Article dans une revue hal-02348648v1

T-Bet Plays a Key Role in NK-Mediated Control of Melanoma Metastatic Disease

Miriam Werneck , Geanncarlo Lugo-Villarino , Eun Sook Hwang , Harvey Cantor , Laurie Glimcher

Journal of Immunology, 2008, 180 (12), pp.8004-8010. ⟨10.4049/jimmunol.180.12.8004⟩

Article dans une revue hal-02348657v1

Supplemental Data Communicable Ulcerative Colitis Induced by T-Bet Deficiency in the Innate Immune System

Wendy S Garrett , Graham M Lord , Shivesh Punit , Geanncarlo Lugo-Villarino , Sarkis Mazmanian et al.

Cell, 2007

Article dans une revue hal-03020444v1

Cutting Edge: STAT1 and T-bet Play Distinct Roles in Determining Outcome of Visceral Leishmaniasis Caused by Leishmania donovani

Lucia Rosas , Heidi Snider , Joseph Barbi , Anjali Satoskar , Geanncarlo Lugo-Villarino et al.

Journal of Immunology, 2006, 177 (1), pp.22-25. ⟨10.4049/jimmunol.177.1.22⟩

Article dans une revue hal-02348669v1

Identification and characterization of lung commensal bacteria that modulate immune response in Tuberculosis

Lucie Bernard-Raichon , André Colom , Margaux Cescato , Céline Cougoule , Pauline Guilloton et al.

103. Annual Meeting of the American Association of Immunologists, American Association of Immunologists, May 2019, San Diego, CA, United States

Communication dans un congrès hal-04171999v1