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Guilhem Pages

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### **RESEARCH EXPERIENCE** **Since AgroResonance platform, UR370 QuaPA**, INRA, Saint-Genès-Champanelle, France **2014/10** *Research engineer* · Optimize and write NMR/MRI methods and protocols to match customer requirements · Develop *in-situ* low-field NMR · Work under ISO 9001 management system **2014/03 Biomedical NMR Group UMR 5068**, Paul Sabatier University, Toulouse, France **2014/09** *Postdoctoral researcher in Professor M. Malet-Martino’s group* · Optimized diffusion NMR data acquisition to deformulate complex mixtures · Characterized adulteration in supplement diets by benchtop NMR **2011/02 Singapore BioImaging Consortium**, A\*STAR, Singapore **2014/02** *Senior research fellow* · Characterised *in-vivo* and *in-vitro* biological pathways by Dynamic Nuclear Polarization (DNP) NMR · Modelized biological pathways to estimate kinetic parameters from DNP experimental data · Studied brain activity by Gluco-CEST · Maintained the NMR spectrometer **2010/02 Physical Chemistry Department**, Royal Institute of Technology (KTH), Stockholm, Sweden **2011/01** *Postdoctoral researcher in Professor I. Furò’s group* · Measured and explained water diffusion in wood · Characterised interactions between wood and oil · Developed pulse sequence for diffusion measurements in complex system **2007/01 School of Molecular and Microbial Biosciences**, University of Sydney, Sydney, Australia **2009/12** *Postdoctoral researcher in Professor P. W. Kuchel’s group* · Implemented fast diffusion pulse sequences to study erythrocyte shape evolution · Studied starch digestion by NMR and electrophoretic NMR · Characterised peptide structure (hERG, TASK2) · Developed NMR pulse sequence **2003/10 Research unit JE 2421 TRACES**, Paul Cézanne University, Marseille, France **2006/10** *Post-graduate student.* · Developed a new NMR technique that improves the resolution of NMR diffusion experiments: “Chromatographic NMR” · Optimized HPLC assay of Saint John’s Wort’s naphthodianthrones · Maintenance and troubleshooting of spectrometers and HPLC equipment **2002/09 Pharmaceutical laboratory DistriB3**, Marseille, France **2003/09** *Laboratory technician.* · Identified plants and determined active principles using Pharmacopoeia monographs · Developed analytical methods **2002/02 Synthesis, Catalysis and Chirality Laboratory**, Paul Cézanne University, Marseille **2002/08** *Graduate student*, MS training period. · Synthesized chromatographic phase and characterized them by IR and Solid state NMR **2001/07 Sanofi~Synthélabo**, Process development laboratory, Montpellier, France **2001/10** *Laboratory student*, BS training period. · Developed and extrapolated a drug synthesis · Synthesized in the preproduction unit **1999/04 Pierre Fabre**, Industrial and chemical development center, Gaillac, France **1999/07** *Laboratory student*, Training period. · Optimized the synthesis of an active molecule ### **GRANTS & AWARDS** - **French research national agency (ANR),** 2019 (4y, € 487 528) *OutLabMRI: A unique MR imager outside the laboratory : new horizons in agro-ecosystems* - **I-SITE CAP 20-25, PhD grant,** 2018 (3y, € 90 000) *Développement et validation d’un nouveau capteur pour mesurer* in situ *et localement les quantités et flux d’eau dans les agroécosystèmes* - **I-SITE CAP 20-25 EMERGENCE,** 2018 (1y, € 30 000) *Augmenter la sensibilité de l’imagerie du 13C hyperpolarisé par polarisation croisée : premières démonstrations* in vivo - **Ligue régionale contre le cancer,** 2016 (2y, € 40 000) *Développement d’une méthode d’imagerie innovante contrastant les caractéristiques du microenvironnement du chondrosarcome: diagnostic et suivi de nouvelles prodrogues bispécifiques* - **Joint Council Office Exploratory Grant,** 2013 (1y, SGD$ 133 000) *Enabling multi-nuclear dynamic nuclear polarization - nuclear magnetic resonance (DNP-NMR)* - **University of Sydney Bridging Support Grant,** 2009 (1y, AUS$ 20 000) *NMR diffusion and exchange spectroscopy for studying chemical transformation in heterogeneous biochemical systems* - **Magnetic Resonance in Chemistry Award for young scientist,** 2006 (1500 €) - **3rd poster prize** (2 books) in Chemometric 2005 congress - **3-years PhD grant** (2003-2006) from the French Conseil Régional de Provence-Alpes-Côte d’Azur ### **EDUCATION** - **HDR, 2019,** University Clermont Auvergne, Clermont-Ferrand, France *“IRM: du laboratoire au champ”* - **PhD in Physical Chemistry, 2006,** University Paul Cézanne, Marseille, France *“Chromatographic NMR”* Supervisor: Professor Stefano Caldarelli - **Engineering degree, 2002,** University Paul Cézanne, Marseille, France National Higher School of Chemical Synthesis, Process and Engineering (ENSSPICAM) - **MS** **in organic chemistry, 2002,** University Paul Cézanne, Marseille, France *A new chromatographic phase based on cholesterol ether. Synthesis and characterization.*

Publications

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Use of a portable MRI to evaluate root structure-function relationships in water-use for several herbaceous species

Magali Nuixe , Amidou Sissou Traoré , Shannan Blystone , J.-M. Bonny , Guilhem Pagès
Plant and Soil, inPress
Journal articles hal-04729444v1
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Interhemispheric reactivity of the subthalamic nucleus sustains progressive dopamine neuron loss in asymmetrical parkinsonism

Pascal Salin , Christophe Melon , Carine Chassain , Guilhem Pagès , Bruno Pereira
Neurobiology of Disease, 2024, 191, pp.106398. ⟨10.1016/j.nbd.2023.106398⟩
Journal articles hal-04408699v1
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Towards portable MRI in the plant sciences

Shannan Blystone , Magali Nuixe , Amidou Sissou Traoré , Hervé Cochard , Catherine Picon-Cochard
Plant Methods, 2024, 20 (1), pp.31. ⟨10.1186/s13007-024-01152-z⟩
Journal articles hal-04487647v1
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Characterization of the sodium binding state in several food products by 23 Na nuclear magnetic resonance spectroscopy

Nour El Sabbagh , Jean-Marie Bonny , Sylvie Clerjon , Carine Chassain , Guilhem Pagés
Magnetic Resonance in Chemistry, 2022, pp.1-9. ⟨10.1002/mrc.5250⟩
Journal articles hal-03613378v1

Quantitative sodium MRI in food: addressing sensitivity issues using single quantum chemical shift imaging at high field

Sylvie Clerjon , Nour El Sabbagh , Guilhem Pagès , Amidou Traoré , J.-M. Bonny
Magnetic Resonance in Chemistry, 2022, 60 (7), pp.628-636. ⟨10.1002/mrc.5239⟩
Journal articles hal-03537396v1
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Simultaneous proteoglycans and hypoxia mapping of chondrosarcoma environment by frequency selective CEST MRI

Roxane Autissier , Leslie Mazuel , Elise Maubert , Jean‐marie Bonny , Philippe Auzeloux
Magnetic Resonance in Medicine, inPress, 86 (2), pp.1008-1018. ⟨10.1002/mrm.28781⟩
Journal articles hal-03187913v1

Correction to : MRSI vs CEST MRI to understand tomato metabolism in ripening fruit: is there a better contrast ?

Guilhem Pagés , Catherine Deborde , Martine Lemaire-Chamley , Annick Moing , Jean-Marie Bonny
Analytical and Bioanalytical Chemistry, 2021, 413 (6), pp.1777-1777. ⟨10.1007/s00216-021-03180-3⟩
Journal articles hal-03297107v1
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Circadian Variation of Root Water Status in Three Herbaceous Species Assessed by Portable NMR

Magali Nuixe , Amidou Sissou Trao , Shannan Blystone , J.-M. Bonny , Robert Falcimagne
Plants, 2021, 10 (4), ⟨10.3390/plants10040782⟩
Journal articles hal-03200198v1
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Low field, time domain NMR in the agriculture and agrifood sectors: An overview of applications in plants, foods and biofuels

Luiz Alberto Colnago , Zeev Wiesman , Guilhem Pagès , Maja Musse , Tatiana Monaretto
Journal of Magnetic Resonance, 2021, 323, 9 p. ⟨10.1016/j.jmr.2020.106899⟩
Journal articles hal-03136584v1

MRSI vs CEST MRI to understand tomato metabolism in ripening fruit: is there a better contrast?

Guilhem Pagès , Catherine Deborde , Martine Lemaire-Chamley , Annick Moing , J.-M. Bonny
Analytical and Bioanalytical Chemistry, 2021, 413, pp.1251-1257. ⟨10.1007/s00216-020-03101-w⟩
Journal articles hal-03101885v1
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Effects of Long-Term Endogenous Corticosteroid Exposure on Brain Volume and Glial Cells in the AdKO Mouse

Jorge Miguel Amaya , Ernst Suidgeest , Isabelle Sahut-Barnola , Typhanie Dumontet , Nathanaëlle Montanier
Frontiers in Neuroscience, 2021, 15, pp.604103. ⟨10.3389/fnins.2021.604103⟩
Journal articles hal-03138884v1
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Spurious phase correction in rapid metabolic imaging

Nour El Sabbagh , Carine Chassain , H. Ratiney , Guilhem Pagés , J.-M. Bonny
Journal of Magnetic Resonance, 2021, 332 (107065), pp.107065. ⟨10.1016/j.jmr.2021.107065⟩
Journal articles hal-03363454v1
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Parsimonious discretization for characterizing multi‐exponential decay in magnetic resonance

J.-M. Bonny , Amidou Traore , Mustapha Bouhrara , Richard Spencer , Guilhem Pagès
NMR in Biomedicine, 2020, 33 (12), ⟨10.1002/nbm.4366⟩
Journal articles hal-02926295v1
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Antioxidant and Cardio-protective Effects of epa in Early Low-severity Sepsis through ucp3- and sirt3-upholding of the Mitochondrial Redox Potential

Thibault Léger , Kasra Azarnoush , Amidou Traoré , Lucie Cassagnes , Jean-Paul Rigaudière
Oxidative Medicine and Cellular Longevity, 2019, 2019, 21 p. ⟨10.1155/2019/9710352⟩
Journal articles hal-02282312v1

Uncertainties of calculated Cramér-Rao lower bounds: implications for quantitative MRS

J.-M. Bonny , Guilhem Pages
Magnetic Resonance in Medicine, 2019, 81 (2), pp.759-764. ⟨10.1002/mrm.27415⟩
Journal articles hal-02621447v1
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Glyoxalase activity in human erythrocytes and mouse lymphoma, liver and brain probed with hyperpolarized C-13-methylglyoxal

Dmitry Shishmarev , Philip W. Kuchel , Guilhem Pages , Alan J. Wright , Richard L. Hesketh
Communications Biology, 2018, 1, ⟨10.1038/s42003-018-0241-1⟩
Journal articles hal-02624539v1
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mGlu5 receptor antagonist blocks bromocriptine-induced conditioned place preference in bilateral mesolimbic-lesioned rat

Omar Ouachikh , Carine Chassain , Guilhem Pages , Franck Durif , Aziz Hafidi
Behavioural Brain Research, 2017, 317, pp.301 - 310. ⟨10.1016/j.bbr.2016.09.030⟩
Journal articles hal-01690871v1

The impact of processing and aging on the oxidative potential, molecular structure and dissolution of gelatin.

Anne Duconseille , Mounir Traikia , Marie Lagrée , Cyril Jousse , Guilhem Pagès
Food Hydrocolloids, 2017, 66, pp.246-258. ⟨10.1016/j.foodhyd.2016.11.034⟩
Journal articles hal-01546098v1

Pulsed Field Gradient NMR with Sigmoid Shape Gradient Sampling To Produce More Detailed Diffusion Ordered Spectroscopy Maps of Real Complex Mixtures: Examples with Medicine Analysis

Guilhem Pages , Alice Bonny , Véronique Gilard , Myriam Malet-Martino
Analytical Chemistry, 2016, 88 (6), pp.3304-3309. ⟨10.1021/acs.analchem.5b04781⟩
Journal articles hal-02061365v1

FmRα analysis: Rapid and direct estimation of relaxation and kinetic parameters from dynamic nuclear polarization time courses

Guilhem Pages , Philip Kuchel
Magnetic Resonance in Medicine, 2015, 73 (6), pp.2075-2080. ⟨10.1002/mrm.25345⟩
Journal articles hal-02631754v1

Long-lived spin state of a tripeptide in stretched hydrogel

Kaz Nagashima , D. Krishna Rao , Guilhem Pages , S. Sendhil Velan , Philipw Kuchel
Journal of Biomolecular NMR, 2014, 59 (1), pp.31-41. ⟨10.1007/s10858-014-9821-7⟩
Journal articles hal-02636735v1

Evaluation of a Benchtop Cryogen-Free Low-Field 1H NMR Spectrometer for the Analysis of Sexual Enhancement and Weight Loss Dietary Supplements Adulterated with Pharmaceutical Substances

Guilhem Pages , Anna Gerdova , David Williamson , Véronique Gilard , Robert Martino
Analytical Chemistry, 2014, 86 (23), pp.11897-11904. ⟨10.1021/ac503699u⟩
Journal articles hal-02063995v1

Dependence of residual dipolar couplings on foot angle in 1H MR spectra from skeletal muscle

Nikita Agarwal , Guilhem Pages , Loyola d' Silva , Nicholas Said , Philip W Kuchel
Magnetic Resonance Imaging, 2014, 32 (4), pp.379-384. ⟨10.1016/j.mri.2014.01.001⟩
Journal articles hal-02629885v1

Structure and antimicrobial activity of platypus ‘intermediate’ defensin-like peptide

Allan Torres , Paramjit Bansal , Jennifer Koh , Guilhem Pages , Wu Ming
FEBS Letters, 2014, 588 (9), pp.1821-1826. ⟨10.1016/j.febslet.2014.03.044⟩
Journal articles hal-02632080v1

Hyperpolarized [1,13C]pyruvate in lysed human erythrocytes: effects of co-substrate supply on reaction time courses

Guilhem Pages , Yee Ling Tan , Philip W. Kuchel
NMR in Biomedicine, 2014, 27 (10), pp.1203-1210. ⟨10.1002/nbm.3176⟩
Journal articles hal-02632293v1

‘Chiral compartmentation’ in metabolism: Enzyme stereo-specificity yielding evolutionary options

Philip W. Kuchel , Guilhem Pages , Christoph Naumann
FEBS Letters, 2013, 587 (17), pp.2790-2797. ⟨10.1016/j.febslet.2013.05.025⟩
Journal articles hal-02646847v1
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Mathematical modeling and data analysis of NMR experiments using hyperpolarized 13C metabolites

Guilhem Pages , Philip W. Kuchel
Magnetic Resonance Insights, 2013, 6, pp.13-21. ⟨10.4137/mri.s11084⟩
Journal articles hal-02643047v1

Imaging brain deoxyglucose uptake and metabolism by glucoCEST MRI

Fatima A. Nasrallah , Guilhem Pages , Philip W. Kuchel , Xavier Golay , Kai-Hsiang Chuang
Journal of Cerebral Blood Flow and Metabolism, 2013, 33 (8), pp.1270-1278. ⟨10.1038/jcbfm.2013.79⟩
Journal articles hal-02652679v1

Insights into hERG K+ channel structure and function from NMR studies

Chaiann Ng , Allanm Torres , Guilhem Pages , Philipw Kuchel , Jamiei Vandenberg
European Biophysics Journal, 2013, 42 (1), pp.71-79. ⟨10.1007/s00249-012-0808-6⟩
Journal articles hal-02645294v1

NMR q-space analysis of canonical shapes of human erythrocytes: stomatocytes, discocytes, spherocytes and echinocytes

Timothyj Larkin , Guilhem Pages , Bogdane Chapman , Johne J. Rasko , Philipw Kuchel
European Biophysics Journal, 2013, 42 (1), pp.3-16. ⟨10.1007/s00249-012-0822-8⟩
Journal articles hal-02647193v1

Suppressing magnetization exchange effects in stimulated-echo diffusion experiments

Guilhem Pages , Sergey V. Dvinskikh , Istvan Furo
Journal of Magnetic Resonance, 2013, 234, pp.35-43. ⟨10.1016/j.jmr.2013.06.001⟩
Journal articles hal-02650941v1

Transmembrane exchange of hyperpolarized 13C-urea in human erythrocytes: subminute timescale kinetic analysis

Guilhem Pages , Max Puckeridge , Guo Liangfeng , Yee ling Tan , Chacko Jacob
Biophysical Journal, 2013, 105 (9), pp.1956-1966
Journal articles hal-02646248v1

Stejskal–tanner equation derived in full

Philip W. Kuchel , Guilhem Pages , Kaz Nagashima , Sendhil Velan , Vimalan Vijayaragavan
Concepts in Magnetic Resonance Part A: Bridging Education and Research, 2012, 40A (5), pp.205-214. ⟨10.1002/cmr.a.21241⟩
Journal articles hal-02647775v1

Polymer binding to carbon nanotubes in aqueous dispersions: residence time on the nanotube surface as obtained by NMR diffusometry

Anton E. Frise , Guilhem Pages , Michael Shtein , Ilan Pri Bar , Oren Regev
Journal of Physical Chemistry B, 2012, 116 (9), pp.2635-2642. ⟨10.1021/jp209800u⟩
Journal articles hal-02644450v1

Simultaneous estimation of T1 and the flip angle in hyperpolarized NMR experiments using acquisition at non-regular time intervals

Max Puckeridge , Guilhem Pages , Philip W. Kuchel
Journal of Magnetic Resonance, 2012, 222, pp.68-73. ⟨10.1016/j.jmr.2012.06.006⟩
Journal articles hal-02645762v1

Vegetable oil reactions within wood studied by direct 13C excitation with 1H decoupling and magic-angle sample spinning (MAS) NMR

Guilhem Pages , Alireza M. Salehi , Sergey V. Dvinskikh , Mats K. G. Johansson , Istvan Furo
Progress in Organic Coatings, 2012, 75 (3), pp.259-263. ⟨10.1016/j.porgcoat.2012.05.007⟩
Journal articles hal-02648737v1

Kinetics of starch hydrolysis and glucose mutarotation studied by NMR chemical exchange saturation transfer (CEST)

Anthony C. Dona , Guilhem Pages , Philip W. Kuchel
Carbohydrate Polymers, 2011, 86 (4), pp.1525-1532. ⟨10.1016/j.carbpol.2011.06.056⟩
Journal articles hal-02644539v1

Starch granule characterization by kinetic analysis of their stages during enzymic hydrolysis: 1H nuclear magnetic resonance studies

Anthony C. Dona , Guilhem Pages , Robert G. Gilbert , Philip W. Kuchel
Carbohydrate Polymers, 2011, 83 (4), pp.1775-1786. ⟨10.1016/j.carbpol.2010.10.042⟩
Journal articles hal-02646434v1

Mass Transport of Volatile Molecules in Porous Materials: Evaporation-Condensation Phenomena Described by NMR Diffusometry

Caroline Carrara , Guilhem Pages , Corinne Delaurent , Stéphane Viel , Stefano Caldarelli
Journal of Physical Chemistry C, 2011, 115 (38), pp.18776--18781. ⟨10.1021/jp2074607⟩
Journal articles hal-01460272v1

Oxidation of methyl linoleate in the presence of lignin

Alireza M. Salehi , Guilhem Pages , Istvan Furo , Gunnar Henriksson , Mats Johansson
Progress in Organic Coatings, 2011, 72, pp.325-333. ⟨10.1016/j.porgcoat.2011.05.004⟩
Journal articles hal-02646203v1

Erythrocyte shape reversion from echinocytes to discocytes: Kinetics via fast-measurement NMR diffusion-diffraction

Guilhem Pages , T. W. Yau , P. W. Kuchel
Magnetic Resonance in Medicine, 2010, 64 (3), pp.645-652. ⟨10.1002/mrm.22457⟩
Journal articles hal-02664294v1

Digestion of starch: In vivo and in vitro kinetic models used to characterise oligosaccharide or glucose release

Anthony C. Dona , Guilhem Pagès , Robert G. Gilbert , Philip W. Kuchel
Carbohydrate Polymers, 2010, 80 (3), pp.599-617
Journal articles hal-02666672v1
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Kinetics of in vitro digestion of starches monitored by time-resolved1H nuclear magnetic resonance

Anthony C. Dona , Guilhem Pages , Robert G. Gilbert , Marianne Gaborieau , Philip W. Kuchel
Biomacromolecules, 2009, 10 (3), pp.638-644. ⟨10.1021/bm8014413⟩
Journal articles hal-02658070v1
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The pore domain outer helix contributes to both activation and inactivation of the hERG K+ channel

Pengchu Ju , Guilhem Pages , Peter Riek , Po-Chia Chen , Allan Torres
Journal of Biological Chemistry, 2009, 284 (2), pp.1000-1008. ⟨10.1074/jbc.M806400200⟩
Journal articles hal-02666154v1

Structure of the pore-helix of the hERG K+ channel

Guilhem Pages , Allan M. Torres , Pengchu Ju , Paramjit S. Bansal , Paul F. Alewood
European Biophysics Journal, 2009, 39 (1), pp.111-120. ⟨10.1007/s00249-009-0433-1⟩
Journal articles hal-02663771v1
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Pulsed field gradient magic angle spinning NMR self-diffusion measurements in liquids

Stéphane Viel , Fabio Ziarelli , Guilhem Pages , Caroline Carrara , Stefano Caldarelli
Journal of Magnetic Resonance, 2008, 190 (1), pp.113-123. ⟨10.1016/j.jmr.2007.10.010⟩
Journal articles hal-02666155v1

Cholesteric bonded stationary phases for high-performance liquid chromatography: a comparative study of the chromatographic behavior

Cédric Courtois , Guilhem Pages , Stefano Caldarelli , Corinne Delaurent
Analytical and Bioanalytical Chemistry, 2008, 392 (3), pp.451-461. ⟨10.1007/s00216-008-2276-5⟩
Journal articles hal-02666966v1
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Erythrocyte-shape evolution recorded with fast-measurement NMR diffusion-diffraction

Guilhem Pages , David Szekely , Philip W. Kuchel
Journal of Magnetic Resonance Imaging, 2008, 28 (6), pp.1409-1416. ⟨10.1002/jmri.21588⟩
Journal articles hal-02655917v1
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Different chemometric approaches to optimize the assay of St. John's Wort active ingredients

Guilhem Pages , Corinne Delaurent , Roger Phan-Tan-Luu , Michelle Sergent
Chemometrics and Intelligent Laboratory Systems, 2007, 86 (2), pp.159-167. ⟨10.1016/j.chemolab.2006.06.006⟩
Journal articles hal-02659854v1

Optimization of the assay of naphthodianthrones in dry St John’s wort extract by reversed-phase liquid chromatography

Guilhem Pages , Michael Mazarin , Michelle Sergent , Roger Phan-Tan-Luu , Corinne Delaurent
Analytical and Bioanalytical Chemistry, 2006, 385 (4), pp.716-723. ⟨10.1007/s00216-006-0426-1⟩
Journal articles hal-02664542v1
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Investigation of the chromatographic process via pulsed-gradient spin−echo nuclear magnetic resonance. Role of the solvent composition in partitioning chromatography

Guilhem Pages , Corinne Delaurent , Stefano Caldarelli
Analytical Chemistry, 2006, 78 (2), pp.561-566. ⟨10.1021/ac051454n⟩
Journal articles hal-02665659v1
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Simplified analysis of mixtures of small molecules by chromatographic NMR spectroscopy

Guilhem Pages , Corinne Delaurent , Stefano Caldarelli
Angewandte Chemie International Edition, 2006, 45 (36), pp.5950-5953. ⟨10.1002/anie.200601622⟩
Journal articles hal-02665660v1
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Détermination des volumes morts et des eff ets extra-colonne en chromatographie liquide de partage à polarité de phase inversée

Corinne Delaurent , Guilhem Pages , Stéphane Alphéran
Spectra Analyse, 2005, 245, pp.36-46
Journal articles hal-02683632v1

Optimization of St John's Wort flavonoid separation by reversed phase liquid chromatography on a silica-based monolithic column

C. Brenier-Maurel , C. Delaurent , Guilhem Pages , M. -C. Guilhem , A. M. Siouffi
Chromatographia, 2002, 56 (5-6), pp.277-282. ⟨10.1007/BF02491932⟩
Journal articles hal-02682605v1
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Quantitative 23Na MRI in food during sodium diffusion

Raphaël Monod , J.-M. Bonny , Guilhem Pagès , Thierry Thomas-Danguin , Sylvie Clerjon
16th International Conference on the Applications of Magnetic Resonance in Food Science, Antonio Gilberto Ferreira, Federal University of Sao Carlos - Brazil, Jun 2024, Foz Do Iguazu, Brazil
Conference papers hal-04624915v1

Evaluer la réponse thérapeutique tumorale : intérêt d'une approche bimodale en IRM CEST et imagerie nucléaire

Roxane Autissier , Erwan Boutault , Jean-Marie Bonny , Philippe Auzeloux , Emmanuel Moreau
6ème Congrès scientifique de la socièté Française de Résonance Magnétique en Biologie et Médicine (SFRMBM) 2023, SFRMBM, Mar 2023, Paris, France
Conference papers hal-04086942v1
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Caractérisation de l'état de liaison du sel dans les produits alimentaires par relaxométrie RMN du 23Na

Sylvie Clerjon , Diamantino Agripino da Cunha , Amidou Traoré , Guilhem Pagès , J.-M. Bonny
Journées RMN du Grand Sud, May 2023, Lyon, France
Conference papers hal-04115255v1
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MUTANT : a new image filtering paradigm for improved parameters determination. Application to myelin water fraction mapping and sodium concentrations imaging

J.-M. Bonny , Wafaa Zaaraoui , Mohamed-Mounir El Mendili , Guilhem Pagès , Mustapha Bouhrara
ISMRM workshop, Sep 2023, Nashville (Tennessee), United States
Conference papers hal-04235727v1
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Transportable MRI to characterize water in plants directly in their natural environment

Guilhem Pagès
NMR for Life Sciences, Oct 2023, Nantes, France
Conference papers hal-04238193v1
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Measuring tree water content in-situ with a portable, unilateral magnet

Shannan Blystone , Guilhem Pagès , Hervé H. Cochard , Pierre Conchon
4emes Journées RMN du Grand Sud, May 2023, Lyon, France
Conference papers hal-04117301v1
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MEASURING TREE WATER CONTENT AND LOCATING CONDUCTIVE TISSUES WITH PORTABLE MRI

S Blystone , Guilhem Pagès , H Cochard , P Conchon
Journées de l'Ecole Doctorale, Université Clermont Auvergne, Jun 2023, Clermont Ferrand (FR), France
Conference papers hal-04133747v1
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Measuring tree water content with a portable, unilateral magnet

Shannan Blystone , Guilhem Pagès , Hervé H. Cochard , Pierre Conchon
GERM 2023, Jun 2023, Murol, France
Conference papers hal-04133617v1
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Sound Zones mobiles

Guilhem Pagès , Manuel Melon , Laurent Simon , Luna Timbal , Valentin Bourrud
16ème Congrès Français d'Acoustique, Apr 2022, Marseille, France
Conference papers hal-03651588v1
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MRSI vs CEST MRI to understand tomato metabolism during fruit development: Is there a better contrast?

Guilhem Pagès , Catherine Deborde , Martine Lemaire-Chamley , Annick Moing , J.-M. Bonny
15th edition of the International Conference on the Applications of Magnetic Resonance in Food Science (MRFOOD2022), Jun 2022, Aarhus, Denmark
Conference papers hal-03695147v1
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A portable and unilateral nmr device to measure tree water and locate conductive tissues

Shannan Blystone , Guilhem Pagès , Hervé H. Cochard , Pierre Conchon
Congrès Italian-French International Conference on Magnetic Resonance, Sep 2022, Milan, Italy
Conference papers hal-03822545v1
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Can metabolic mri be useful to image tomato metabolism?

Guilhem Pagès , Catherine Deborde , Martine Lemaire-Chamley , Moing A Lemaire-Chamley , J.-M. Bonny
International Plant Spectroscopy Conference (IPSC), Sep 2022, Nantes, France
Conference papers hal-03781345v1
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Characterization of sodium relaxation in food: a mandatory step to reach quantitative sodium images

Sylvie Clerjon , Guilhem Pagès , El Sabbagh , Amidou Traoré , J.-M. Bonny
15. International Conference on the Applications of Magnetic Resonance in Food Science, Jun 2022, Aarhus, Denmark
Conference papers hal-03757144v1
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Low-field mri: a useful tool to characterize water in intact plants

Nuixe Magali , Guilhem Pagès , J.-M. Bonny , Amidou Traoré , Catherine Picon-Cochard
International Plant Spectroscopy Conference (IPSC), Sep 2022, Nantes, France
Conference papers hal-03781364v1

TUMOR MICROENVIRONMENT IMAGING: MULTIMODALITY BENEFIT TO STUDY CHONDROSARCOMA

Roxane Autissier , Leslie Mazuel , Elise Maubert , J.-M. Bonny , Philippe Auzeloux
EMIM 2021, Aug 2021, Göttingen, Germany
Conference papers hal-03345202v1
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État hydrique des racines de plantes prairiales évalué par RMN portable

Magali Nuixe , Amidou Traoré , Shannan Blystone , J.-M. Bonny , Robert Falcimagne
GERM, Apr 2021, Online, France
Conference papers hal-03377555v1
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Quantitative sodium MRI in foods : addressing sensitivity issues using single quantum Chemical Shift Imaging at high field

Sylvie Clerjon , Nour El Sabbagh , Guilhem Pagès , Amidou Traoré , J.-M. Bonny
Applications of Magnetic Resonance in Food Science: Multiscale Food Structures and FoodOmics, Groupement Ampere, Oct 2021, distanciel, France
Conference papers hal-03579561v1
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Digestion du pain: rôle de la phase orale, de la variété de blé et du procédé de panification dans la modulation de la digestion du gluten de pain

Marie-Agnès Peyron , Mélany Genot , Thierry Sayd , Guilhem Pagès , Vincenza Ferraro
Journées Francophones de Nutrition, Nov 2021, LIlle, France
Conference papers hal-03758348v1
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IMAGERIE METABOLIQUE RAPIDE DE MOLECULES HYPERPOLARISEES : A LA RECHERCHE DU TEMPS PERDU

El Sabbagh Nour , Carine Chassain , Guilhem Pages , Jean-Marie Bonny
Journées du Grand Sud, Jul 2021, CLERMONT-FERRAND, France. ⟨10.15454/1.5572398324758228E12⟩
Conference papers hal-03334089v1
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Phase Correction in IDEAL-type Rapid Spectroscopic Imaging

Nour El Sabbagh , Carine Chassain , Hélène Ratiney , Guilhem Pagès , J.-M. Bonny
ISMRM 2021 Annual meeting, May 2021, Online, France
Conference papers hal-03238486v1
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Can NMR become a tool of choice to study ecosystems directly in the fields?

Guilhem Pagès
Compact NMR conference II, Oct 2021, Online, France
Conference papers hal-03419138v1
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Assessment of the sensitivity of a low-field NMR sensor by characterizing root water status of an herbaceous plant under drought conditions

Magali Nuixe , Amidou Traoré , J.-M. Bonny , Guilhem Pagès , Catherine Picon-Cochard
Compact NMR Conference II, Oct 2021, Nantes, France
Conference papers hal-03377468v1
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Benefit of multimodal MRI to follow in vivo tumor microenvironment changes during therapy

Roxane Autissier , Leslie Mazuel , J.-M. Bonny , Philippe Auzeloux , Sébastien Schmitt
5th SFRMBM, Sep 2021, LYON, France
Conference papers hal-03369601v1
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Spatial Localization of Metabollites In Fruits By NMR : Tissue Dissection and Metabolic Profiling Or Non-Invasive Whole Fruite Imaging ?

Lemaire-Chamley Martine , Guilhem Pagès , Deborde Catherine , Mounet Fabien , Maucourt Mickael
3. Journées RMN du Grand-Sud, Jul 2021, Clermont-Ferrand, France
Conference papers hal-03757279v1
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L'IRM CEST est-elle un contraste intéressant pouŕ etudier les agroressources et les produits transformés?

Guilhem Pagès , Jean Marie Bonny
1ère conférence virtuelle du GERM, Apr 2020, Online, France
Conference papers hal-03238264v1
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Incertitude de la borne de Cramée-Rao: conséquences en SRM quantitative

J.-M. Bonny , Guilhem Pages
4. Congrès de la Société Française de Résonance Magnétique en Biologie et Médecine, Mar 2019, Strasbourg, France
Conference papers hal-02734461v1

Suivi longitudinal du métabolisme cérébral par imagerie spectroscopique de résonance magnétique nucléaire chez des modèles murins progressifs de la maladie de Parkinson

Carine Chassain , Christophe Melon , Guilhem Pages , Yann Le Fur , Paolo Gubellini
4. Congrès de la Société Française de Résonance Magnétique en Biologie et Médecine, Mar 2019, Strasbourg, France
Conference papers hal-02734202v1
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Multi échelles, multi contrastes, l’Imagerie par Résonance Magnétique pour l’agronomie, l’agro-alimentaire et la nutrition

S. Clerjon , Amidou Traore , Guilhem Pages , J.-M. Bonny
8. Journées Scientifiques et Techniques du Réseau des Microscopistes de l'INRA, 2018, Clermont-Ferrand, France
Conference papers hal-02733824v1
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A robust and prior knowledge independent method to interpret non-negative least squares (NNLS) T2 relaxation results

Guilhem Pages , Amidou Traore , J.-M. Bonny
14. International Conference on the Applications of Magnetic Resonance in Food Science, Sep 2018, Rennes, France
Conference papers hal-02736963v1
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IRM de l'aliment à l'alimentation

Guilhem Pages
Journée scientifique de la fédération FJV, Nov 2018, Nancy, France
Conference papers hal-02785689v1
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CEST MRI to contrast chondrosarcoma tumors: two contrasts in one acquisition

Leslie Mazuel , Roxane Autissier , Eric Maubert , A. Voissiere , Valérie Weber-Haddad
13. European Molecular Imaging Meeting, Mar 2018, San Sebastián, Spain
Conference papers hal-02733597v1

To which extent the Cramér-Rao bound (CRB) is a reliable benchmark in quantitative MRS ?

Guilhem Pages , J.-M. Bonny
ISMRM 2018, Jun 2018
Conference papers hal-02735231v1
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CEST-MRI to reveal new contrasts: application in preclinical imaging and food science

Guilhem Pages , J.-M. Bonny
2ème Journée RMN du Grand-Sud, Jun 2018, Toulouse, France
Conference papers hal-02787903v1

CEST MRI to contrast chondrosarcoma tumors: two contrasts in one acquisition

Leslie Mazuel , Roxanne Autissier , Elise Maubert , Aurélien Voissiere , Valérie Weber
Congrès EMIM European Society of Molecular Imaging, Mar 2018, SAN SEBASTIAN, Spain
Conference papers hal-01938943v1
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Incertitude de la borne de Cramér-Rao : conséquences en spectroscopie RMN quantitative

Guilhem Pages , J.-M. Bonny
20. GERM Congress, May 2017, Aussois, France
Conference papers hal-01607389v1

Une vision pragmatique de l’analyse multiexponentielle des décroissances obtenues en RMN

Guilhem Pages , Amidou Traore , J.-M. Bonny
20. GERM Congress, May 2017, Aussois, France
Conference papers hal-01607351v1
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Low- and high-field NMR spectrometry: complementarity in the struggle against counterfeiting

Guilhem Pages , Véronique Gilard , Robert Martino , Myriam Malet-Martino
1ère Journée Grand-sud de RMN, May 2016, Montpellier, France
Conference papers hal-02795728v1
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Quantitative in-situ NMR to characterize protein oxidation and its dynamics

Guilhem Pages , Amaël Morisse , Philippe P. Gatellier , Estelle Martineau , Patrick Giraudeau
13. International Conference on the Applications of Magnetic Resonance in Food Science, Jun 2016, Karlsruhe, Germany. 1 p
Conference papers hal-02793518v1
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Towards the discrimination of gelatin by hrmas: role of processing on its chemical composition

Anne Duconseille , Guilhem Pages , Mounir Traïkia , Marie Lagrée , Cyril Jousse
61. International Congress of Meat Science and Technology (ICoMST), Aug 2015, Clermont-Ferrand, France
Conference papers hal-02742338v1
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CHARACTERIZATION OF WATER STATE AND REPARTITION DURING DRYING PROCESS OF TOMATO WITH SINGLE SIDED NUCLEAR MAGNETIC RESONANCE

Amidou Traoré , Guilhem Pagès , Sylvie Clerjon , Alexandre Leca , Nadia Bertin
16th Bienniel International Bologna Conference Magnetic Resonance In Porous Media, Aug 2024, Tromso, Norway. 2014
Conference poster hal-04683948v1
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The challenge to get MRI metabolic maps in fleshy fruit: tomato example

Guilhem Pagès , Catherine Deborde , Martine Lemaire-Chamley , Annick Moing , Jean-Marie Bonny
16th Biennial International Bologna Conference Magnetic Resonance in Porous Media, Aug 2024, Tromso, Norvège, Norway
Conference poster hal-04683887v1
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Evaluation of a unilateral magnet to characterize water in root systems

Magali Nuixe , Guilhem Pagès , Jean-Marie Bonny , Catherine Pichon-Cochard , Amidou Traore
16th Bienniel International Bologna Conference Magnetic Resonance in Porous Media, Aug 2024, Tromso, Norvège, Norway
Conference poster hal-04683911v1
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A portable and unilateral NMR device to measure tree water content and locate conductive tissues

Shannan Blystone , Guilhem Pagès , Hervé H. Cochard , Pierre Conchon
Italian-French International Conference on Magnetic Resonance, Sep 2022, Milan, Italy
Conference poster hal-03822537v1
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Characterization of sodium relaxation in food : a mandatory step to reach quantitative sodium images

Sylvie Clerjon , Guilhem Pagès , Nour El Sabbagh , Amidou Traoré , J.-M. Bonny
15. International Conference on the Applications of Magnetic Resonance in Food Science, Jun 2022, Aarhus, Denmark
Conference poster hal-03757121v1
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Correction de phase pour l'Imagerie Spectroscopique Rapide

Nour El Sabbagh , Carine Chassain , Helene Ratiney , Guilhem Pagès , J.-M. Bonny
5. Congrès de la Société Française de Résonance Magnétique en Biologie et Médecine (SFRMBM), Sep 2021, LYON, France
Conference poster hal-03757198v1
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Réaliser des mesures en extérieur avec un aimant unilatéral : Comment s'affranchir des biais de mesure RMN dus aux variations de température

Benmoussa Abdlatif , Nuixe Magali , Bonny Jean-Marie , Guilhem Pagès , Traoré Amidou
Journées RMN du Grand Sud, Jul 2021, Clermont-Ferrand, France
Conference poster hal-03331815v1
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IMAGERIE METABOLIQUE RAPIDE DE MOLECULES HYPERPOLARISEES : A LA RECHERCHE DU TEMPS PERDU

El Sabbagh Nour , Carine Chassain , Guilhem Pages , Jean-Marie Bonny
Journées RMN du Grand Sud, Jul 2021, Clermont-Ferrand, France
Conference poster hal-03331830v1

Spatial localization of metabolites in fruits by NMR: tissue dissection and metabolic profiling or non-invasive whole fruit imaging?

Martine Lemaire-Chamley , Guilhem Pagès , Catherine Deborde , Fabien Mounet , Mickaël Maucourt
Journées RMN du Grand-Sud, Jul 2021, Clermont-Ferrand, France
Conference poster hal-03329972v1
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Tumor microenvironment imaging: Benefits of multimodality to study chondrosarcoma

Roxane Autissier , ; Leslie Mazuel , Elise Maubert , Jean-Marie Bonny , Philippe Auzeloux
Journées du Grand Sud, Jul 2021, CLERMONT-FERRAND, France. ⟨10.18145/ivia)⟩
Conference poster hal-03334046v1
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Imagerie Métabolique Rapide de Molécules Hyperpolarisées : à la Recherche du Temps Perdu

El Sabbagh Nour , Chassain Carine , Guilhem Pagès , J.-M. Bonny
Journées du Grand Sud, Jul 2021, CLERMONT-FERRAND, France. 2021, ⟨10.15454/1.5572398324758228E12⟩
Conference poster hal-03334100v1
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To dissect or not to dissect for fruit spatial metabolomics : tissue profiling or MRI

Martine Lemaire-Chamley , Guilhem Pagès , Catherine Deborde , Fabien F. Mounet , Mickael Maucourt
3. Journées RMN du Grand-Sud, Jul 2021, Clermont-Ferrand, France
Conference poster hal-03757356v1
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Prédiction de la teneur en eau des racines par spectroscopie proche infra-rouge

Catherine Picon-Cochard , Magali Nuixe , Pierrick Arnault , Amidou Traoré , Guilhem Pagès
Workshop INRAE Imagerie des Sols, Oct 2021, Saint Rémy-lès-Chevreuse, France
Conference poster hal-04138768v1
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To dissect or not to dissect for fruit spatial metabolomics: tissue profiling or MRI?

Martine Lemaire-Chamley , Guilhem Pagès , Catherine Deborde , Fabien Mounet , Mickael Maucourt
Metabolomics, Jun 2021, online meeting, France
Conference poster hal-03757407v1
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La RMN portable pour caractériser les racines de plantes prairiales

Magali Nuixe , Amidou Traoré , Shannan Blystone , J.-M. Bonny , Robert Falcimagne
Journées du Grand Sud, Jul 2021, CLERMONT-FERRAND, France. 2021
Conference poster hal-03347761v1
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LA RMN PORTABLE POUR CARACTERISER LES RACINES DE PLANTES PRAIRIALES

Magali Nuixe , Amidou Traoré , Shannan Blystone , J.-M. Bonny , Robert Falcimagne
Journées RMN du Grand Sud, Jul 2021, Clermont-Ferrand, France
Conference poster hal-03331827v1
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TUMOR MICROENVIRONMENT IMAGING: BENEFITS OF MULTIMODALITY TO STUDY CHONDROSARCOMA

Roxane Autissier , ; Leslie Mazuel , Elise Maubert , Jean-Marie Bonny , Philippe Auzeloux
Journées RMN du Grand Sud, Jul 2021, Clermont-Ferrand, France
Conference poster hal-03331842v1
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Spurious phase correction in multi-shot CSI

Nour El Sabbagh , Carine Chassain , Hélène Ratiney , Guilhem Pagès , J.-M. Bonny
ESMRMB 2020 - 37th annual meeting, Sep 2020, Inconnu, France
Conference poster hal-03238472v1
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A new approach to interpret non-negative least squares (NNLS) T2relaxation results

Guilhem Pages , Amidou Traore , J.-M. Bonny
EUROISMAR, Aug 2019, Berlin, Germany. 2019
Conference poster hal-02734560v1
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Profiling the temperature dependent frequency of an open-magnet for outdoor applications

Amidou Traore , Corinne C. Rondeau-Mouro , Rim Aliouissi , Abdlatif Benmoussa , J.-M. Bonny
EUROISMAR, Aug 2019, Berlin, Germany. 2019
Conference poster hal-02735518v1
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Développement et caractérisation de modèles d’études précliniques de chondrosarcome

Elise Maubert , Roxane Autissier , Aurélien Voissiere , Yvain Gerard , Sébastien Schmitt
Journées Scientifiques du CLARA (Cancéropôle Lyon Auvergne Rhône-Alpes), Apr 2019, Lyon, France. 2019
Conference poster hal-02734873v1
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Imagerie métabolique rapide en 13C

Nour El Sabbagh , J.-M. Bonny , Franck Durif , Hélène Ratiney , Guilhem Pages
Petit GERM, May 2019, Oléron, France. 2019
Conference poster hal-02733862v1
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Profiling the temperature dependent frequency of an open-magnet for outdoor applications

Amidou Traore , Rim Aliouissi , Guilhem Pages , J.-M. Bonny
International Conference on Magnetic Resonance Microscopy, ICMRM, Aug 2019, Paris, France. 2019
Conference poster hal-02735961v1
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Profiling the temperature dependent frequency of an open-magnet for outdoor applications

Amidou Traoré , Corinne Rondeau-Mouro , Rim Aliouissi , Abdlatif Benmoussa , Jean-Marie Bonny
International Society of Magnetic Resonance, Aug 2019, Berlin, Germany
Conference poster hal-04113288v1
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Intérêt de l'imagerie IRM-CEST in-vivo pour l'étude du microenvironnement tumoral du chondrosarcome

Roxane Autissier , Elise Maubert , Sébastien Schmicke , Philippe Auzeloux , Caroline Peyrode
4ème congrès de la société française de résonance magnétique en biologie & médecine, Mar 2019, Strasbourg, France. 2019
Conference poster hal-02734277v1
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CEST MRI to contrast chondrosarcoma tumors: two contrasts in one acquisition

Leslie Mazuel , A. Voissiere , Valérie Weber , Yvain Gerard , Sophie Besse
ISMRM 2018, Jun 2018, Paris, France. 2018
Conference poster hal-02736532v1
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Diffusion MRI in muscles at high b-values: towards a quantification of microscopic organelles

Nicolas Moutal , Denis S Grebenkov , S. Clerjon , Guilhem Pages , J.-M. Bonny
ISMRM 2018, Jun 2018, Paris, France. 2018
Conference poster hal-02734828v1
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Longitudinal follow-up of brain metabolism in rat models of progressive Parkinson's disease using Magnetic Resonance Spectroscopy Imaging

Carine Chassain , Christophe Melon , Guilhem Pages , Yann Le Fur , P Salin
ISMRM 2018, 2018, 2018
Conference poster hal-02737966v1
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Cardiac MRI assessment of the effects of dietary Eicosapentaenoic acid (EPA) on the adverse consequences of sepsis

Amidou Traore , Thibault Leger , Guilhem Pages , Lucie Cassagnes , Kasra Azarnoush
Joint Annual Meeting ISMRM-ESMRMB, Jun 2018, Paris, France. 2018
Conference poster hal-01824991v1
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A new approach to interpret non-negative least squares (NNLS) relaxation results

Guilhem Pages , Amidou Traore , J.-M. Bonny
EUROMAR, Jul 2018, Nantes, France. 2018
Conference poster hal-02737455v1
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Can CEST contrast image gluten network?

Charbel Assaf , Guilhem Pages , J.-M. Bonny
14. International Conference on the Applications of Magnetic Resonance in Food Science, Sep 2018, Rennes, France. 2018
Conference poster hal-02735065v1

Effect of the exposure of gelatin to various environmental conditions on its chemical composition

Anne Duconseille , Guilhem Pages , M. Traikiac , Marie Lagrée , Cyril Jousse
1. Journées Grand Sud de RMN, May 2016, Montpellier, France. 2016
Conference poster hal-01602923v1
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Suivi de l'oxydation des acides gras et des protéines par RMN quantitative pour une meilleure maîtrise des qualités sensorielles et nutritionnelles des aliments

Guilhem Pages , Amaël Morisse , Philippe P. Gatellier , Patrick Giraudeau , J.-M. Bonny
Groupe d’Etude de Résonance Magnétique, May 2015, Sète, France. 1 p., 2015
Conference poster hal-02743150v1

Low-field 1H NMR spectrometer for the analysis of dietary supplements adulterated with pharmaceutical substances

Guilhem Pages , Anna Gerdova , David Williamson , Véronique Gilard , Robert Martino
Combating Counterfeit Medicines: the Solutions, Mar 2015, London, United Kingdom. , 1 p., 2015
Conference poster hal-02741139v1
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La "RMN Chromatographique"

Guilhem Pagès
Chimie analytique. Université Paul Cézanne (Aix Marseille 3), 2006. Français. ⟨NNT : ⟩
Theses tel-03238234v1
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Développements méthodologiques en IRM: du laboratoire au champ

Guilhem Pages
Ingénierie des aliments. Université Clermont Auvergne, 2019
Habilitation à diriger des recherches tel-02790086v1