GL

Guy Lippens

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Publications

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Bacillus subtilis utilizes decarboxylated S-adenosylmethionine for the biosynthesis of tandem aminopropylated microcin C, a potent inhibitor of bacterial aspartyl-tRNA synthetase

Alexey Kulikovsky , Eldar Yagmurov , Anastasiia Grigoreva , Aleksandr Popov , Konstantin Severinov et al.
Journal of the American Chemical Society, In press, ⟨10.1021/jacs.4c18468⟩
Article dans une revue hal-05014998 v1

A widespread family of ribosomal peptide metallophores involved in bacterial adaptation to metal stress

Laura Leprevost , Sophie Jünger , Guy Lippens , Céline Guillaume , Giuseppe Sicoli et al.
Proceedings of the National Academy of Sciences of the United States of America, 2024, 121 (49), pp.e2408304121. ⟨10.1073/pnas.2408304121⟩
Article dans une revue hal-04811059 v1
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The structure of a Tau fragment bound to tubulin prompts new hypotheses on Tau mechanism and oligomerization

Liza Ammar Khodja , Valérie Campanacci , Guy Lippens , Benoît Gigant
Article dans une revue hal-04771509 v1
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New route to a pyrazoline scaffold featuring original substitutions and its crystal structure

Guy Lippens , Nicolas Jean-Bart , Emmanuel Gras
Chemical Monthly = Monatshefte für Chemie, 2024, 155 (2), pp.183-188. ⟨10.1007/s00706-023-03169-x⟩
Article dans une revue hal-04669669 v1
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Exploring the pH dependence of an improved PETase

Cyril Charlier , Sabine Gavalda , Jelena Grga , Laura Perrot , Valeria Gabrielli et al.
Biophysical Journal, In press, ⟨10.1016/j.bpj.2024.04.026⟩
Article dans une revue hal-04569437 v1
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Biochemical characterization of a SusD-like protein involved in β-1,3-glucan utilization by an uncultured cow rumen Bacteroides

Xiaoqian Li , Guy Lippens , Jean-Luc Parrou , Gianluca Cioci , Jérémy Esque et al.
MSphere, 2024, 9 (8), ⟨10.1128/msphere.00278-24⟩
Article dans une revue hal-04743213 v1
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Catalytic enantiospecific deuteration of complex amino acid mixtures with ruthenium nanoparticles

Gabriel Mencia , Pauline Rouan , Pier-Francesco Fazzini , Hanna Kulyk , Victor Varela-Izquierdo et al.
Catalysis Science & Technology, 2024, 14 (17), pp.4904-4911. ⟨10.1039/D4CY00588K⟩
Article dans une revue hal-04778743 v1
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Structural and Biochemical Characterization of a Nonbinding SusD-Like Protein Involved in Xylooligosaccharide Utilization by an Uncultured Human Gut <i>Bacteroides</i> Strain

Alexandra Tauzin , Zhi Wang , Gianluca Cioci , Xiaoqian Li , Aurore Labourel et al.
MSphere, 2023, 7 (5), ⟨10.1128/msphere.00244-22⟩
Article dans une revue hal-03796391 v1
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An NMR look at an engineered PET depolymerase

Cyril Charlier , Sabine Gavalda , Vinciane Borsenberger , Sophie Duquesne , Alain Marty et al.
Biophysical Journal, In press, 121 (15), pp.2882-2894. ⟨10.1016/j.bpj.2022.07.002⟩
Article dans une revue hal-03739009 v1
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Characterization of a Family of Scorpion Toxins Modulating Ca2+-Activated Cl− Current in Vascular Myocytes

Jean-Luc Morel , Nathalie Mokrzycki , Guy Lippens , Hervé Drobecq , Pierre Sautière et al.
Toxins, 2022, 14 (11), pp.780. ⟨10.3390/toxins14110780⟩
Article dans une revue hal-03864126 v1
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Proline-Rich Region II (PRR2) Plays an Important Role in Tau–Glycan Interaction: An NMR Study

Anqesha Murray , Lufeng Yan , James Gibson , Jian Liu , David Eliezer et al.
Biomolecules, 2022, 12 (11), pp.1573. ⟨10.3390/biom12111573⟩
Article dans une revue (data paper) hal-03832416 v1
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The Jo-In protein welding system is a relevant tool to create CBM-containing plant cell wall degrading enzymes

Louise Badruna , Vincent Burlat , Pierre Roblin , Thomas Enjalbert , Guy Lippens et al.
New Biotechnology, 2021, 65, pp.31-41. ⟨10.1016/j.nbt.2021.07.004⟩
Article dans une revue hal-03340154 v1
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Improved NMR Detection of Phospho-Metabolites in a Complex Mixture

Neil Cox , Pierre Millard , Cyril Charlier , Guy Lippens
Analytical Chemistry, 2021, 93 (11), pp.4818-4824. ⟨10.1021/acs.analchem.0c04056⟩
Article dans une revue hal-03171690 v2
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Virtual decoupling to break the simplification versus resolution trade-off in nuclear magnetic resonance of complex metabolic mixtures

Cyril Charlier , Neil Cox , Sophie Prud'Homme , Alain Geffard , Jean-Marc Nuzillard et al.
Magnetic Resonance, 2021, 2, pp.619-627. ⟨10.5194/mr-2-619-2021⟩
Article dans une revue hal-03338624 v1

IsoSolve: An Integrative Framework to Improve Isotopic Coverage and Consolidate Isotopic Measurements by Mass Spectrometry and/or Nuclear Magnetic Resonance

Pierre Millard , Serguei Sokol , Michael Kohlstedt , Christoph Wittmann , Fabien Létisse et al.
Analytical Chemistry, 2021, 93 (27), pp.9428-9436. ⟨10.1021/acs.analchem.1c01064⟩
Article dans une revue hal-03307270 v1
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The covalent complex of Jo-In results from a long-lived, non-covalent intermediate state with near-native structure

Neil Cox , Cyril Charlier , Ramadoss Vijayaraj , Marion de La Mare , Sophie Barbe et al.
Biochemical and Biophysical Research Communications, 2021, 589, pp.223-228. ⟨10.1016/j.bbrc.2021.12.028⟩
Article dans une revue hal-03554277 v1
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Identification and characterization of andalusicin: N-terminally dimethylated class III lantibiotic from Bacillus thuringiensis sv. andalousiensis

Anastasiia Grigoreva , Julia Andreeva , Dmitry Bikmetov , Anastasiia Rusanova , Marina Serebryakova et al.
iScience, 2021, 24 (5), ⟨10.1016/j.isci.2021.102480⟩
Article dans une revue hal-03270626 v1
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The Zebra Mussel (Dreissena polymorpha) as a Model Organism for Ecotoxicological Studies: A Prior 1H NMR Spectrum Interpretation of a Whole Body Extract for Metabolism Monitoring

Sophie Martine Prud’homme , Younes Mohamed Ismail Hani , Neil Cox , Guy Lippens , Jean-Marc Nuzillard et al.
Metabolites, 2020, 10 (6), pp.256. ⟨10.3390/metabo10060256⟩
Article dans une revue hal-02934872 v1

Increasing field strength versus advanced isotope labeling for NMR based fluxomics

Mickael Dinclaux , Edern Cahoreau , Pierre Millard , Fabien Letisse , Guy Lippens
Magnetic Resonance in Chemistry, 2020, pp.1-7. ⟨10.1002/mrc.4988⟩
Article dans une revue hal-02438088 v1

Backbone chemical shift assignment of macrophage infectivity potentiator virulence factor of Trypanosoma cruzi

Juan M. Lopez , Ricardo Antiparra , Guy Lippens , Mirko Zimic , Patricia Sheen et al.
Biomolecular NMR Assignments, 2019, 13 (1), pp.21-25. ⟨10.1007/s12104-018-9844-1⟩
Article dans une revue hal-02170460 v1
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Cyclophilin A allows the allosteric regulation of a structural motif in the disordered domain 2 of NS5A and thereby fine-tunes HCV RNA replication

Marie Dujardin , Vanesa Madan , Neha S Gandhi , François-Xavier Cantrelle , Hélène Launay et al.
Journal of Biological Chemistry, 2019, 294 (35), pp.13171-13185. ⟨10.1074/jbc.RA119.009537⟩
Article dans une revue hal-02998113 v1
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Elucidating Tau function and dysfunction in the era of cryo-EM

Guy Lippens , Benoît Gigant
Journal of Biological Chemistry, In press, 294 (24), pp.9316-9325. ⟨10.1074/jbc.REV119.008031⟩
Article dans une revue hal-02137974 v1

Efficient in vivo synthesis of lasso peptide pseudomycoidin proceeds in the absence of both the leader and the leader peptidase

Tatyana Zyubko , Marina Serebryakova , Julia Andreeva , Mikhail Metelev , Guy Lippens et al.
Chemical Science, 2019, 10 (42), pp.9699-9707. ⟨10.1039/C9SC02370D⟩
Article dans une revue hal-02368109 v1

Integrated pH Measurement during Reaction Monitoring with Dual-Reception 1 H– 31 P NMR Spectroscopy

Neil Cox , Rainer Kuemmerle , Pierre Millard , Edern Cahoreau , Jean-Marie François et al.
Analytical Chemistry, 2019, 91 (6), pp.3959-3963. ⟨10.1021/acs.analchem.8b05147⟩
Article dans une revue hal-02131891 v1
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Tuning the catalytic activity and selectivity of water-soluble bimetallic RuPt nanoparticles by modifying their surface metal distribution

Donia Bouzouita , Guy Lippens , Edwin A Baquero , Pier-Francesco Fazzini , Grégory Pieters et al.
Nanoscale, 2019, 11 (35), pp.16544-16552. ⟨10.1039/C9NR04149D⟩
Article dans une revue hal-02283913 v2

Major Differences between the Self-Assembly and Seeding Behavior of Heparin-Induced and in Vitro Phosphorylated Tau and Their Modulation by Potential Inhibitors

Clément Despres , Jing Di , François-Xavier Cantrelle , Zizheng Li , Isabelle Huvent et al.
ACS Chemical Biology, 2019, 14 (6), pp.1363-1379. ⟨10.1021/acschembio.9b00325⟩
Article dans une revue hal-02317189 v1

Futile Encounter Engineering of the DSR-M Dextransucrase Modifies the Resulting Polymer Length

Marion Claverie , Gianluca Cioci , Matthieu Guionnet , Julia Schörghuber , Roman Lichtenecker et al.
Biochemistry, 2019, 58 (25), pp.2853-2859. ⟨10.1021/acs.biochem.9b00373⟩
Article dans une revue hal-02176417 v1
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Efficient Access to Deuterated and Tritiated Nucleobase Pharmaceuticals and Oligonucleotides using Hydrogen-Isotope Exchange

Alberto Palazzolo , Sophie Feuillastre , Viktor Pfeifer , Sébastien Garcia-Argote , Donia Bouzouita et al.
Angewandte Chemie International Edition, 2019, 58 (15), pp.4891-4895. ⟨10.1002/anie.201813946⟩
Article dans une revue cea-02075752 v1

Improved Isotopic Profiling by Pure Shift Heteronuclear 2D J -Resolved NMR Spectroscopy

Davy Sinnaeve , Mickael Dinclaux , Edern Cahoreau , Pierre Millard , Jean-Charles Portais et al.
Analytical Chemistry, 2018, 90 (6), pp.4025-4031. ⟨10.1021/acs.analchem.7b05206⟩
Article dans une revue hal-02131883 v1

The Neuronal tau protein blocks in vitro fibrillation of the amyloid-beta (A beta) peptide at the oligomeric stage

Cecilia Wallin , Yoshitaka Hiruma , Sebastian K. T. S. Warmlander , Isabelle Huvent , Juri Jarvet et al.
Journal of the American Chemical Society, 2018, 140 (26), pp.8138-8146. ⟨10.1021/jacs.7b13623⟩
Article dans une revue hal-02154329 v1

In-cell NMR: from metabolites to macromolecules

Guy Lippens , Edern Cahoreau , Pierre Millard , C. Charlier , J. Lopez et al.
Analyst, 2018, 143 (3), pp.620-629. ⟨10.1039/C7AN01635B⟩
Article dans une revue hal-01886451 v1

Interaction study between HCV NS5A-D2 and NS5B using 19F NMR

Marie Dujardin , François-Xavier Cantrelle , Guy Lippens , Xavier Hanoulle
Journal of Biomolecular NMR, 2018, 70 (1), pp.67-76. ⟨10.1007/s10858-017-0159-9⟩
Article dans une revue hal-01886452 v1

Overall Structural Model of NS5A Protein from Hepatitis C Virus and Modulation by Mutations Confering Resistance of Virus Replication to Cyclosporin A

Aurélie Badillo , Véronique Receveur-Brechot , Stéphane Sarrazin , François-Xavier Cantrelle , Frédéric Delolme et al.
Biochemistry, 2017, 56 (24), pp.3029 - 3048. ⟨10.1021/acs.biochem.7b00212⟩
Article dans une revue hal-01785410 v1

Monitoring of nanoparticle reactivity in solution: interaction of l -lysine and Ru nanoparticles probed by chemical shift perturbation parallels regioselective H/D exchange

Luis Miguel Martinez-Pietro , Edwin A Baquero , Grégory Pieters , Juan Flores , Ernesto de Jesus et al.
Chemical Communications, 2017, 53 (43), pp.5850-5853. ⟨10.1039/c7cc02445b⟩
Article dans une revue hal-02004103 v1

Metabolic phenotyping of human plasma by H-1-NMR at high and medium magnetic field strengths: a case study for lung cancer

Evelyne Louis , Francois-Xavier Cantrelle , Liesbet Mesotten , Gunter Reekmans , Liene Bervoets et al.
Magnetic Resonance in Chemistry, 2017, 55 (8), pp.706-713. ⟨10.1002/mrc.4577⟩
Article dans une revue hal-01886450 v1
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Investigations on the Determinants Responsible for Low Molar Mass Dextran Formation by DSR-M Dextransucrase

Marion Claverie , Gianluca Cioci , Marlène Vuillemin , Nelly Monties , Pierre Roblin et al.
ACS Catalysis, 2017, 7 (10), pp.7106-7119. ⟨10.1021/acscatal.7b02182⟩
Article dans une revue hal-01886431 v1

Glycan Determinants of Heparin-Tau Interaction

Jing Zhao , Isabelle Huvent , Guy Lippens , David Eliezer , Anqiang Q. Zhang et al.
Biophysical Journal, 2017, 112 (5), pp.921-932. ⟨10.1016/j.bpj.2017.01.024⟩
Article dans une revue hal-01600157 v1
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Structure and antagonism of the receptor complex mediated by human TSLP in allergy and asthma

Kenneth Verstraete , Frank Peelman , Harald Braun , Juan Lopez , Dries van Rompaey et al.
Nature Communications, 2017, 8 (1), 17 p. ⟨10.1038/ncomms14937⟩
Article dans une revue hal-01605011 v1
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NMR reveals the intrinsically disordered domain 2 of NS5A protein as an allosteric regulator of the hepatitis C virus RNA polymerase NS5B

Luiza Bessa , Hélène Launay , Marie Dujardin , Xavier Cantrelle , Guy Lippens et al.
Journal of Biological Chemistry, 2017, 292 (44), pp.18024-18043. ⟨10.1074/jbc.M117.813766⟩
Article dans une revue hal-01620117 v1
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Identification of the Tau phosphorylation pattern that drives its aggregation

Clement Despres , Cillian Byrne , Haoling Qi , François-Xavier Cantrelle , Isabelle Huvent et al.
Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (34), pp.9080 - 9085. ⟨10.1073/pnas.1708448114⟩
Article dans une revue hal-01620128 v1

(15)N-NMR-based approach for amino acids-based (13)C-metabolic flux analysis of metabolism

Pierre Millard , Edern Cahoreau , Maud Heuillet , Jean-Charles Portais , Guy Lippens
Analytical Chemistry, 2017, 89 (3), pp.2101-2106. ⟨10.1021/acs.analchem.6b04767⟩
Article dans une revue hal-01602563 v1

A β-Turn Motif in the Steroid Hormone Receptor’s Ligand-Binding Domains Interacts with the Peptidyl-prolyl Isomerase (PPIase) Catalytic Site of the Immunophilin FKBP52

Cillian Byrne , Morkos A. Henen , Mathilde Belnou , François-Xavier Cantrelle , Amina Kamah et al.
Biochemistry, 2016, 55 (38), pp.5366 - 5376. ⟨10.1021/acs.biochem.6b00506⟩
Article dans une revue hal-01389826 v1
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NMR Meets Tau: Insights into Its Function and Pathology

Guy Lippens , Isabelle Landrieu , Caroline Smet , Isabelle Huvent , Neha Gandhi et al.
Ancient biomolecules, 2016, 6 (2), ⟨10.3390/biom6020028⟩
Article dans une revue (article de synthèse) hal-01389829 v1

Proline Conformation in a Functional Tau Fragment

Puneet Ahuja , Xavier Cantrelle , Isabelle Huvent , Xavier Hanoulle , Juan Lopez et al.
Journal of Molecular Biology, 2016, 428 (1), pp.79 - 91. ⟨10.1016/j.jmb.2015.11.023⟩
Article dans une revue hal-01389832 v1

Studying Intrinsically disordered proteins under true in vivo conditions by combined cross-polarization and carbonyl-detection NMR spectroscopy

Juan Lopez , Robert Schneider , Francois-Xavier Cantrelle , Isabelle Huvent , Guy Lippens
Angewandte Chemie International Edition, 2016, 55 (26), pp.7418-7422. ⟨10.1002/anie.201601850⟩
Article dans une revue istex hal-01886415 v1
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Characterization of Neuronal Tau Protein as a Target of Extracellular Signal-regulated Kinase

Haoling Qi , Sudhakaran Prabakaran , François-Xavier Cantrelle , Béatrice Chambraud , Jeremy Gunawardena et al.
Journal of Biological Chemistry, 2016, 291 (14), pp.7742 - 7753. ⟨10.1074/jbc.M115.700914⟩
Article dans une revue hal-01389831 v1

The FK506-binding protein FKBP52 in vitro induces aggregation of truncated Tau forms with prion-like behavior.

Julien Giustiniani , Kevin Guillemeau , Omar Dounane , Elodie Sardin , Isabelle Huvent et al.
FASEB Journal, 2015, Epub ahead of print
Article dans une revue hal-01145979 v1
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Tau phosphorylation regulates the interaction between BIN1’s SH3 domain and Tau’s proline-rich domain

Yoann Sottejeau , Alexis Bretteville , François-Xavier Cantrelle , Nicolas Malmanche , Florie Demiaute et al.
Acta Neuropathologica Communications, 2015, 3 (1), ⟨10.1186/s40478-015-0237-8⟩
Article dans une revue hal-01221659 v1

A Phosphorylation-Induced Turn Defines the Alzheimer's Disease AT8 Antibody Epitope on the Tau Protein.

Neha S Gandhi , Isabelle Landrieu , Cillian Byrne , Predrag Kukic , Laziza Amniai et al.
Angewandte Chemie International Edition, 2015, 127 (23), pp.6923-6927 ⟨10.1002/ange.201501898⟩
Article dans une revue istex hal-01145963 v1

Mechanism of Tau-promoted microtubule assembly as probed by NMR spectroscopy.

Benoît Gigant , Isabelle Landrieu , Caroline Fauquant , Pascale Barbier , Isabelle Huvent et al.
Journal of the American Chemical Society, 2014, pp.12615-23
Article dans une revue hal-01077829 v1

A functional fragment of Tau forms fibers without the need for an intermolecular cysteine bridge.

Isabelle Huvent , Amina Kamah , François-Xavier Cantrelle , Nicolas Barois , Christian Slomianny et al.
Biochemical and Biophysical Research Communications, 2014, 445 (2), pp.299-303. ⟨10.1016/j.bbrc.2014.01.161⟩
Article dans une revue hal-01077911 v1

Nuclear magnetic resonance analysis of the acetylation pattern of the neuronal Tau protein.

Amina Kamah , Isabelle Huvent , François-Xavier Cantrelle , Haoling Qi , Guy Lippens et al.
Biochemistry, 2014, 53 (18), pp.3020-32. ⟨10.1021/bi500006v⟩
Article dans une revue hal-01077868 v1

Immunophilin FKBP52 induces Tau-P301L filamentous assembly in vitro and modulates its activity in a model of tauopathy.

Julien Giustiniani , Béatrice Chambraud , Elodie Sardin , Omar Dounane , Kevin Guillemeau et al.
Proceedings of the National Academy of Sciences of the United States of America, 2014, pp.4584-9
Article dans une revue hal-01077897 v1

Phosphorylation in intrinsically disordered regions regulates the activity of Neurogenin2.

Gary S Mcdowell , Christopher J Hindley , Guy Lippens , Isabelle Landrieu , Anna Philpott
BMC Biochemistry, 2014, pp.24
Article dans une revue hal-01081937 v1

H/D exchange of a 15 N labelled Tau fragment as measured by a simple Relax-EXSY experiment

Juan Lopez , Puneet Ahuja , Isabelle Landrieu , Francois-Xavier Cantrelle , Isabelle Huvent et al.
Journal of Magnetic Resonance, 2014, Journal of Magnetic Resonance, 249, pp.32-37. ⟨10.1016/j.jmr.2014.10.008⟩
Article dans une revue hal-03235804 v1

Tau pathology modulates Pin1 post-translational modifications and may be relevant as biomarker.

Kunie Ando , Pierre Dourlen , Anne-Véronique Sambo , Alexis Bretteville , Karim Bélarbi et al.
Neurobiol Aging, 2013, 34 (3), pp.757-69. ⟨10.1016/j.neurobiolaging.2012.08.004⟩
Article dans une revue istex hal-00765859 v1

Unraveling a phosphorylation event in a folded protein by NMR spectroscopy: phosphorylation of the Pin1 WW domain by PKA.

Caroline Smet-Nocca , Hélène Launay , Jean-Michel Wieruszeski , Guy Lippens , Isabelle Landrieu
Journal of Biomolecular NMR, 2013, 55 (4), pp.323-37. ⟨10.1007/s10858-013-9716-z⟩
Article dans une revue istex hal-00903359 v1

A new strategy for sequential assignment of intrinsically unstructured proteins based on (15)N single isotope labelling.

Juan Lopez , Puneet Ahuja , Melanie Gerard , Jean-Michel Wieruszeski , Guy Lippens
Journal of Magnetic Resonance, 2013, 236, pp.1-6. ⟨10.1016/j.jmr.2013.07.007⟩
Article dans une revue istex hal-00903369 v1

Hepatitis C Virus NS5B and Host Cyclophilin A share a common binding site on NS5A.

Claire Rosnoblet , Bernd Fritzinger , Dominique Legrand , Hélène Launay , Jean-Michel Wieruszeski et al.
Journal of Biological Chemistry, 2012, epub ahead of print. ⟨10.1074/jbc.M112.392209⟩
Article dans une revue hal-00765873 v1

Towards understanding the phosphorylation code of tau.

Guy Lippens , Laziza Amniai , Jean-Michel Wieruszeski , Alain Sillen , Arnaud Leroy et al.
Biochemical Society Transactions, 2012, 40 (4), pp.698-703. ⟨10.1042/BST20120050⟩
Article dans une revue hal-00765867 v1
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Differential contribution of the repeats to heparin binding of HBHA, a major adhesin of Mycobacterium tuberculosis.

Pierre Lebrun , Dominique Raze , Bernd Fritzinger , Jean-Michel Wieruszeski , Franck Biet et al.
PLoS ONE, 2012, 7 (3), pp.e32421. ⟨10.1371/journal.pone.0032421⟩
Article dans une revue hal-00713026 v1

Cell signaling, post-translational protein modifications and NMR spectroscopy.

Francois-Xavier Theillet , Caroline Smet-Nocca , Stamatios Liokatis , Rossukon Thongwichian , Jonas Kosten et al.
Journal of Biomolecular NMR, 2012, 54 (3), pp.217-36. ⟨10.1007/s10858-012-9674-x⟩
Article dans une revue hal-00765863 v1

Increasing brain protein O-GlcNAc-ylation mitigates breathing defects and mortality of Tau.P301L mice.

Peter Borghgraef , Clément Menuet , Clara Theunis , Justin V Louis , Herman Devijver et al.
PLoS ONE, 2012, pp.e84442
Article dans une revue hal-01077942 v1

Post-translational modification: nature's escape from genetic imprisonment and the basis for dynamic information encoding.

Sudhakaran Prabakaran , Guy Lippens , Hanno Steen , Jeremy Gunawardena
Wiley Interdisciplinary Reviews: Systems Biology and Medicine, 2012, 4 (6), pp.565-83. ⟨10.1002/wsbm.1185⟩
Article dans une revue hal-00765876 v1
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Structural activation of the transcriptional repressor EthR from Mycobacterium tuberculosis by single amino acid change mimicking natural and synthetic ligands

Xavier Carette , Nicolas Blondiaux , Eve Willery , Sylviane Hoos , Nathalie Lecat-Guillet et al.
Nucleic Acids Research, 2011, 40 (7), pp.3018 - 3030. ⟨10.1093/nar/gkr1113⟩
Article dans une revue pasteur-03525621 v1

Systematic identification of tubulin interacting fragments of the microtubule-associated protein TAU leads to a highly efficient promoter of microtubule assembly.

Caroline Fauquant , Virginie Redeker , Isabelle Landrieu , Jean-Michel Wieruzseski , Dries Verdegem et al.
Journal of Biological Chemistry, 2011, epub ahead of print. ⟨10.1074/jbc.M111.223545⟩
Article dans une revue hal-00618268 v1

Domain 3 of NS5A protein from the hepatitis C virus has intrinsic {alpha}-helical propensity and is a substrate of Cyclophilin A.

Dries Verdegem , Aurelie Badillo , Jean-Michel Wieruszeski , Isabelle Landrieu , Arnaud Leroy et al.
Journal of Biological Chemistry, 2011, epub ahead of print. ⟨10.1074/jbc.M110.182436⟩
Article dans une revue hal-00586923 v1

Intermolecular interaction studies using small volumes.

David Bourry , Davy Sinnaeve , Katelijne Gheysen , Bernd Fritzinger , Gianni Vandenborre et al.
Magnetic Resonance in Chemistry, 2011, 49 (1), pp.9-15. ⟨10.1002/mrc.2699⟩
Article dans une revue hal-00586937 v1

Glycerol and glycerol carbonate as ultraviscous solvents for mixture analysis by NMR.

Pedro Lameiras , Leslie Boudesocque , Zéphirin Mouloungui , Jean-Hugues Renault , Jean-Michel Wieruszeski et al.
Journal of Magnetic Resonance, 2011, 212 (1), pp.161-8. ⟨10.1016/j.jmr.2011.06.021⟩
Article dans une revue istex hal-00618281 v1

Identification of O-GlcNAc sites within peptides of the Tau protein and their impact on phosphorylation.

Caroline Smet-Nocca , Malgorzata Broncel , Jean-Michel Wieruszeski , Caroline Tokarski , Xavier Hanoulle et al.
Molecular BioSystems, 2011, 7 (5), pp.1420-9. ⟨10.1039/c0mb00337a⟩
Article dans une revue hal-00586849 v1

Molecular Basis for an Ancient Partnership between Prolyl Isomerase Pin1 and Phosphatase Inhibitor-2.

Furqan Sami , Caroline Smet-Nocca , Meera Khan , Isabelle Landrieu , Guy Lippens et al.
Biochemistry, 2011, 50 (30), pp.6567-78. ⟨10.1021/bi200553e⟩
Article dans une revue hal-00618273 v1

Characterization of the AT180 epitope of phosphorylated Tau protein by a combined nuclear magnetic resonance and fluorescence spectroscopy approach.

Laziza Amniai , Guy Lippens , Isabelle Landrieu
Biochemical and Biophysical Research Communications, 2011, epub ahead of print. ⟨10.1016/j.bbrc.2011.08.046⟩
Article dans une revue istex hal-00618266 v1

Comparative analysis of Erk phosphorylation suggests a mixed strategy for measuring phospho-form distributions.

Sudhakaran Prabakaran , Robert A Everley , Isabelle Landrieu , Jean-Michel Wieruszeski , Guy Lippens et al.
Molecular Systems Biology, 2011, 7, pp.482. ⟨10.1038/msb.2011.15⟩
Article dans une revue hal-00586931 v1

Ranking High Affinity Ligands of Low Solubility by NMR Spectroscopy

Isabelle Landrieu , Xavier Hanoulle , Bernd Fritzinger , Dragos Horvath , Jean-Michel Wieruszeski et al.
ACS Medicinal Chemistry Letters, 2011, 2 (6), pp.485-487. ⟨10.1021/ml200039u⟩
Article dans une revue hal-00618277 v1

Molecular implication of PP2A and Pin1 in the Alzheimer's disease specific hyperphosphorylation of Tau.

Isabelle Landrieu , Caroline Smet-Nocca , Laziza Amniai , Justin Vijay Louis , Jean-Michel Wieruszeski et al.
PLoS ONE, 2011, 6 (6), pp.e21521. ⟨10.1371/journal.pone.0021521⟩
Article dans une revue hal-00618270 v1

Mice lacking phosphatase PP2A subunit PR61/B'{delta} (Ppp2r5d) develop spatially restricted tauopathy by deregulation of CDK5 and GSK3{beta}

Justin V Louis , Ellen Martens , Peter Borghgraef , Caroline Lambrecht , Ward Sents et al.
Proceedings of the National Academy of Sciences of the United States of America, 2011, epub ahead of print. ⟨10.1073/pnas.1018777108⟩
Article dans une revue hal-00586855 v1

Structural basis for the non-immunosuppressive character of the cyclosporin A analogue Debio 025.

Isabelle Landrieu , Xavier Hanoulle , Fanny Bonachera , Arnaud Hamel , Nathalie Sibille et al.
Biochemistry, 2010, 49 (22), pp.4679-86. ⟨10.1021/bi1003266⟩
Article dans une revue hal-00508817 v1

Spectroscopic studies of GSK3β phosphorylation of the neuronal Tau protein and its interaction with the N-terminal domain of apolipoprotein E

Arnaud Leroy , Isabelle Landrieu , Isabelle Huvent , Dominique Legrand , Bernadette Coddeville et al.
Journal of Biological Chemistry, 2010, 285 (43), pp.33435-33444. ⟨10.1074/jbc.M110.149419⟩
Article dans une revue hal-00641629 v1
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Microtubule and MAPs: thermodynamics of complex formation by AUC, ITC, fluorescence, and NMR.

François Devred , Pascale Barbier , Daniel Lafitte , Isabelle Landrieu , Guy Lippens et al.
Methods in Cell Biology, 2010, 95, pp.449-480. ⟨10.1016/S0091-679X(10)95023-1⟩
Article dans une revue hal-00508818 v1

DEB025 (Alisporivir) inhibits hepatitis C virus replication by preventing a cyclophilin A induced cis-trans isomerisation in domain II of NS5A.

Lotte Coelmont , Xavier Hanoulle , Udayan Chatterji , Carola Berger , Joke Snoeck et al.
PLoS ONE, 2010, 5 (10), pp.e13687. ⟨10.1371/journal.pone.0013687⟩
Article dans une revue hal-00586948 v1

Alzheimer disease specific phosphoepitopes of Tau interfere with assembly of tubulin but not binding to microtubules.

Laziza Amniai , Pascale Barbier , Alain Sillen , Jean-Michel Wieruszeski , Vincent Peyrot et al.
FASEB Journal, 2009, 23 (4), pp.1146-52. ⟨10.1096/fj.08-121590⟩
Article dans une revue hal-00348164 v1

Hepatitis C virus NS5A protein is a substrate for the Peptidyl-Prolyl cis/trans isomerase activity of Cyclophilins A and B.

Xavier Hanoulle , Aurélie Badillo , Jean-Michel Wieruszeski , Dries Verdegem , Isabelle Landrieu et al.
Journal of Biological Chemistry, 2009, epub ahead of print. ⟨10.1074/jbc.M809244200⟩
Article dans une revue hal-00373457 v1

Selective backbone labelling of ILV methyl labelled proteins.

Nathalie Sibille , Xavier Hanoulle , Fanny Bonachera , Dries Verdegem , Isabelle Landrieu et al.
Journal of Biomolecular NMR, 2009, 43 (4), pp.219-27. ⟨10.1007/s10858-009-9307-1⟩
Article dans une revue istex hal-00373458 v1

The talin rod IBS2 alpha helix interacts with the beta 3 integrin cytoplasmic tail membrane proximal helix by establishing charge complementary salt bridges.

Sophie Rodius , Olivier Chaloin , Michèle Moes , Elisabeth Schaffner-Reckinger , Isabelle Landrieu et al.
Journal of Biological Chemistry, 2008, epub ahead of print. ⟨10.1074/jbc.M709704200⟩
Article dans une revue hal-00293590 v1

Sandwich-ELISE NMR: reducing the sample volume of NMR samples.

Jean-Michel Wieruszeski , Bernd Fritzinger , Xavier Hanoulle , José C Martins , Guy Lippens
Journal of Magnetic Resonance, 2008, 193 (1), pp.37-40. ⟨10.1016/j.jmr.2008.04.006⟩
Article dans une revue istex hal-00293593 v1

Structural and functional characterisation of the interaction between cyclophilin B and A heparin derived oligosaccharide.

Xavier Hanoulle , Aurélie Melchior , Nathalie Sibille , Benjamin Parent , Agnès Denys et al.
Journal of Biological Chemistry, 2007, epub ahead of print. ⟨10.1074/jbc.M706353200⟩
Article dans une revue hal-00175485 v1

NMR Investigation of the Interaction between the Neuronal Protein Tau and the Microtubules.

Alain Sillen , Pascale Barbier , Isabelle Landrieu , Sylvie Lefebvre , Jean-Michel Wieruszeski et al.
Biochemistry, 2007, 46 (11), pp.3055-3064. ⟨10.1021/bi061920i⟩
Article dans une revue istex hal-00139673 v1

Tau aggregation in Alzheimer's disease : what role for phosphorylation ?

Guy Lippens , Alain Sillen , Isabelle Landrieu , Laziza Amniai , Nathalie Sibille et al.
Prion, 2007, 1 (1), pp.21-25
Article dans une revue hal-00161158 v1

Contribution of rotational diffusion to pulsed field gradient diffusion measurements.

Andrew J Baldwin , John Christodoulou , Paul D Barker , Christopher M Dobson , Guy Lippens
The Journal of Chemical Physics, 2007, 127 (11), pp.114505. ⟨10.1063/1.2759211⟩
Article dans une revue hal-00273334 v1

Studying the natively unfolded neuronal Tau protein by solution NMR spectroscopy.

Guy Lippens , Alain Sillen , Caroline Smet , Jean-Michel Wieruszeski , Arnaud Leroy et al.
Protein and Peptide Letters, 2006, 13, pp.235-246
Article dans une revue hal-00085628 v1

Arabidopsis PASTICCINO2 is an antiphosphatase involved in regulation of cyclin-dependent kinase A.

Marco da Costa , Liên Bach , Isabelle Landrieu , Yannick Bellec , Olivier Catrice et al.
The Plant cell, 2006, 18, pp.1426-1437
Article dans une revue hal-00085654 v1

Selective intracellular accumulation of the major metabolite issued from the activation of the prodrug ethionamide in mycobacteria.

Xavier Hanoulle , Jean-Michel Wieruszeski , Pierre Rousselot-Pailley , Isabelle Landrieu , Camille Locht et al.
Journal of Antimicrobial Chemotherapy, 2006, 58 (4), pp.768. ⟨10.1093/jac/dkl332⟩
Article dans une revue hal-00103724 v1

Pin1 allows for differential Tau dephosphorylation in neuronal cells.

Malika Hamdane , Pierre Dourlen , Alexis Bretteville , Anne-Véronique Sambo , Stéphanie Ferreira et al.
Molecular and Cellular Neuroscience, 2006, 32, pp.155-160
Article dans une revue hal-00085645 v1

Exploring the Molecular Function of PIN1 by Nuclear Magnetic Resonance.

Isabelle Landrieu , Caroline Smet , Jean-Michel Wieruszeski , Anne-Véronique Sambo , René Wintjens et al.
Current Protein and Peptide Science, 2006, 7, pp.179-194
Article dans une revue hal-00085621 v1

New DEFT sequences for the acquisition of one-dimensional carbon NMR spectra of small unlabelled molecules.

Guy Lippens , Jean-Michel Wieruszeski , Marcel Piotto , Karim Elbayed , Marise Bourdonneau
Magnetic Resonance in Chemistry, 2006, 44, pp.943-947
Article dans une revue hal-00103769 v1

Osmoregulated periplasmic glucans of the free-living photosynthetic bacterium Rhodobacter sphaeroides

Philippe Talaga , Virginie Cogez , Jean-Michel Wieruszeski , Bernd Stahl , Jérôme Lemoine et al.
European Journal of Biochemistry, 2002, 269, pp.2464-2472
Article dans une revue hal-00021144 v1

In vivo detection of the cyclic osmoregulated periplasmic glucan of Ralstonia solanacearum by high-resolution magic angle spinning NMR.

Jean-Michel Wieruszeski , Anne Bohin , Jean-Pierre Bohin , Guy Lippens
Journal of Magnetic Resonance, 2001, 151, pp.1-6
Article dans une revue hal-00021378 v1

Recombinant production of the p10CKS1At protein from Arabidopsis thaliana and 13C and 15N double-isotopic enrichment for NMR studies

I. Landrieu , P. Casteels , B. Odaert , Lieven de Veylder , D. Portetelle et al.
Protein Expression and Purification, 1999, 16, pp.144-151
Article dans une revue hal-02686867 v1