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Harald Hampel

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**Professor Harald Hampel** obtained his MD and PhD at the University of Munich, Germany. After training at the University of Munich, he moved to Washington D.C. in 1995 for a post-doctoral fellowship at the National Institutes of Health (NIH), National Institute on Aging (NIA), Laboratory of Neurosciences in Bethesda, Md., USA, focusing on structural &amp; functional neuroimaging of the healthy aging and Alzheimer's disease brain. In 1997 he became founding director of the Alzheimer Memorial Center at the University of Munich where he was appointed as Professor of Psychiatry in 2005. In 2006 he moved to Dublin and was appointed Professor and Chair of Psychiatry at Trinity College, University of Dublin, Ireland. During this time, he was a PI at the Trinity College Institute of Neuroscience (TCIN). In 2010 he was appointed Professor, Chair and Head of Department of Psychiatry, head of the Alzheimer Research Center and co-director of the Brain Imaging Center (BIC) at the University of Frankfurt, Germany. In 2013-2019 he was appointed Professor and AXA Research Fund &amp; Sorbonne University Excellence Chair at Sorbonne University, Institut de la Mémoire et de la Maladie d’Alzheimer (IM2A), Institut du Cerveau et de la Moelle épinière (ICM), at the Department of Neurology, Hôpital Pitié Salpêtrière in Paris, France. Professor Hampel was coordinator of major clinical and translational research programs, in the area of Alzheimer's and other neurodegenerative diseases. In 2019 he joined Eisai Inc. and became Chief Medical Officer, Senior Vice President, Head of Global Medical Affairs, Neurology Business Group, Nutley, NJ, USA. He is founding president of the Alzheimer Precision Medicine Initiative (APMI) and its cohort program (APMI-CP) and heads the international Cholinergic Systems Working Group. <https://www.linkedin.com/in/harald-hampel-md-phd-msc-7496357b/> <https://orcid.org/0000-0003-0894-8982>
**Professor Harald Hampel** obtained his MD and PhD at the University of Munich, Germany. After training at the University of Munich, he moved to Washington D.C. in 1995 for a post-doctoral fellowship at the National Institutes of Health (NIH), National Institute on Aging (NIA), Laboratory of Neurosciences in Bethesda, Md., USA, focusing on structural &amp; functional neuroimaging of the healthy aging and Alzheimer's disease brain. In 1997 he became founding director of the Alzheimer Memorial Center at the University of Munich where he was appointed as Professor of Psychiatry in 2005. In 2006 he moved to Dublin and was appointed Professor and Chair of Psychiatry at Trinity College, University of Dublin, Ireland. During this time, he was a PI at the Trinity College Institute of Neuroscience (TCIN). In 2010 he was appointed Professor, Chair and Head of Department of Psychiatry, head of the Alzheimer Research Center and co-director of the Brain Imaging Center (BIC) at the University of Frankfurt, Germany. In 2013-2019 he was appointed Professor and AXA Research Fund &amp; Sorbonne University Excellence Chair at Sorbonne University, Institut de la Mémoire et de la Maladie d’Alzheimer (IM2A), Institut du Cerveau et de la Moelle épinière (ICM), at the Department of Neurology, Hôpital Pitié Salpêtrière in Paris, France. Professor Hampel was coordinator of major clinical and translational research programs, in the area of Alzheimer's and other neurodegenerative diseases. In 2019 he joined Eisai Inc. and became Chief Medical Officer, Senior Vice President, Head of Global Medical Affairs, Neurology Business Group, Nutley, NJ, USA. He is founding president of the Alzheimer Precision Medicine Initiative (APMI) and its cohort program (APMI-CP) and heads the international Cholinergic Systems Working Group. <https://www.linkedin.com/in/harald-hampel-md-phd-msc-7496357b/> <https://orcid.org/0000-0003-0894-8982>

Publications

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The foundation and architecture of precision medicine in neurology and psychiatry

Harald Hampel , Peng Gao , Jeffrey Cummings , Nicola Toschi , Paul M Thompson et al.
Trends in Neurosciences, inPress, ⟨10.1016/j.tins.2022.12.004⟩
Journal articles hal-03938895v1
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Menopause hormone therapy significantly alters pathophysiological biomarkers of Alzheimer's disease

Herman Depypere , Andrea Vergallo , Pablo Lemercier , Simone Lista , Andrea Benedet et al.
Alzheimer's & Dementia , 2022, ⟨10.1002/alz.12759⟩
Journal articles hal-03942258v1
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Evaluation of major national dementia policies and health‐care system preparedness for early medical action and implementation

Harald Hampel , Andrea Vergallo , Takeshi Iwatsubo , Min Cho , Kiyoshi Kurokawa et al.
Alzheimer's & Dementia , 2022, 18 (10), pp.1993-2002. ⟨10.1002/alz.12655⟩
Journal articles hal-03942260v1
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New insights into the genetic etiology of Alzheimer's disease and related dementias

Celine Bellenguez , Fahri Kucukali , Iris E. Jansen , Luca Kleineidam , Sonia Moreno-Grau et al.
Nature Genetics, 2022, 54 (4), pp.412-436. ⟨10.1038/s41588-022-01024-z⟩
Journal articles hal-03668928v1
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Designing the next-generation clinical care pathway for Alzheimer’s disease

Harald Hampel , Rhoda Au , Soeren Mattke , Wiesje M van der Flier , Paul Aisen et al.
Nature Aging, 2022, 2, 2, pp.692 - 703. ⟨10.1038/s43587-022-00269-x⟩
Journal articles hal-03942256v1
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State‐of‐the‐art of lumbar puncture and its place in the journey of patients with Alzheimer's disease

Harald Hampel , Leslie M Shaw , Paul Aisen , Christopher Chen , Alberto Lleó et al.
Alzheimer's & Dementia , 2022, 18 (1), pp.159-177. ⟨10.1002/alz.12372⟩
Journal articles hal-03942259v1
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Partial Volume Correction Increases the Sensitivity of 18F-Florbetapir-Positron Emission Tomography for the Detection of Early Stage Amyloidosis

Stefan J Teipel , Martin Dyrba , Andrea Vergallo , Simone Lista , Marie Odile Habert et al.
Frontiers in Aging Neuroscience, 2021, 13, ⟨10.3389/fnagi.2021.748198⟩
Journal articles hal-03521540v1
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The Amyloid-β Pathway in Alzheimer’s Disease

Harald Hampel , John Hardy , Kaj Blennow , Christopher Chen , George Perry et al.
Molecular Psychiatry, 2021, 26, pp.5481 - 5503. ⟨10.1038/s41380-021-01249-0⟩
Journal articles hal-03942257v1
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Progress regarding the context-of-use of tau as biomarker of Alzheimer’s disease and other neurodegenerative diseases

Nicole Campese , Giovanni Palermo , Claudia Del Gamba , Maria Francesca Beatino , Alessandro Galgani et al.
Expert Review of Proteomics, 2021, ⟨10.1080/14789450.2021.1886929⟩
Journal articles hal-03138524v1
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Common variants in Alzheimer's disease and risk stratification by polygenic risk scores

Itziar de Rojas , Sonia Moreno-Grau , Niccolo Tesi , Benjamin Grenier-Boley , Victor Andrade et al.
Nature Communications, 2021, 12 (1), pp.3417. ⟨10.1038/s41467-021-22491-8⟩
Journal articles hal-03287265v1
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Association of plasma Aβ40/Aβ42 ratio and brain Aβ accumulation: testing a whole-brain PLS-VIP approach in individuals at risk of Alzheimer's disease

Pablo Lemercier , Andrea Vergallo , Simone Lista , Henrik Zetterberg , Kaj Blennow et al.
Neurobiology of Aging, 2021, 107, pp.57 - 69. ⟨10.1016/j.neurobiolaging.2021.07.005⟩
Journal articles hal-03391168v1
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MiRNA-15b and miRNA-125b are associated with regional Aβ-PET and FDG-PET uptake in cognitively normal individuals with subjective memory complaints

Andrea Vergallo , Simone Lista , Yuhai Zhao , Pablo Lemercier , Stefan Teipel et al.
Translational Psychiatry, 2021, 11, pp.78. ⟨10.1038/s41398-020-01184-8⟩
Journal articles hal-03125818v1

The β-Secretase BACE1 in Alzheimer’s Disease

Harald Hampel , Robert Vassar , Bart de Strooper , John Hardy , Michael Willem et al.
Biological Psychiatry, 2021, 89 (8), pp.745-756. ⟨10.1016/j.biopsych.2020.02.001⟩
Journal articles hal-03197728v1
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Aptamarker prediction of brain amyloid-β status in cognitively normal individuals at risk for Alzheimer’s disease

Gregory Penner , Soizic Lecocq , Anaëlle Chopin , Ximena Vedoya , Simone Lista et al.
PLoS ONE, 2021, 16 (1), pp.e0243902. ⟨10.1371/journal.pone.0243902⟩
Journal articles hal-03212567v1

Association of plasma YKL-40 with brain amyloid-β levels, memory performance, and sex in subjective memory complainers

Andrea Vergallo , Simone Lista , Pablo Lemercier , Patrizia A. Chiesa , Henrik Zetterberg et al.
Neurobiology of Aging, 2020, 96, pp.22 - 32. ⟨10.1016/j.neurobiolaging.2020.07.009⟩
Journal articles hal-03491473v1
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Different Clinical Contexts of Use of Blood Neurofilament Light Chain Protein in the Spectrum of Neurodegenerative Diseases

Giovanni Palermo , Sonia Mazzucchi , Alessandra Della Vecchia , Gabriele Siciliano , Ubaldo Bonuccelli et al.
Molecular Neurobiology, 2020, 57 (11), pp.4667-4691. ⟨10.1007/s12035-020-02035-9⟩
Journal articles hal-03385896v1
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A Path Toward Precision Medicine for Neuroinflammatory Mechanisms in Alzheimer's Disease

Harald Hampel , Filippo Caraci , A. Claudio Cuello , Giuseppe Mario Caruso , Robert Nisticò et al.
Frontiers in Immunology, 2020, 11, pp.456. ⟨10.3389/fimmu.2020.00456⟩
Journal articles hal-02570114v1
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Accuracy of MRI Classification Algorithms in a Tertiary Memory Center Clinical Routine Cohort

Alexandre Morin , Jorge Samper-González , Anne Bertrand , Sebastian Ströer , Didier Dormont et al.
Journal of Alzheimer's Disease, 2020, pp.1-10. ⟨10.3233/JAD-190594⟩
Journal articles hal-02511532v1
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Age and sex impact plasma NFL and t-Tau trajectories in individuals with subjective memory complaints: a 3-year follow-up study

Filippo Baldacci , Simone Lista , Maria Laura Manca , Patrizia A Chiesa , Enrica Cavedo et al.
Alzheimer's Research and Therapy, 2020, 12 (1), pp.147. ⟨10.1186/s13195-020-00704-4⟩
Journal articles hal-03272059v1
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Resting-state posterior alpha rhythms are abnormal in subjective memory complaint seniors with preclinical Alzheimer's neuropathology and high education level: the INSIGHT-preAD study

Claudio Babiloni , Susanna Lopez , Claudio del Percio , Giuseppe Noce , Maria Teresa Pascarelli et al.
Neurobiology of Aging, 2020, 90, pp.43-59. ⟨10.1016/j.neurobiolaging.2020.01.012⟩
Journal articles hal-03006214v1
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Brain Aβ load association and sexual dimorphism of plasma BACE1 concentrations in cognitively normal individuals at risk for AD

Andrea Vergallo , Marion Houot , Enrica Cavedo , Pablo Lemercier , Eugeen Vanmechelen et al.
Alzheimer's and Dementia, 2019, 15, pp.1274 - 1285. ⟨10.1016/j.jalz.2019.07.001⟩
Journal articles hal-03489074v1
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Biomarker-guided clustering of Alzheimer's disease clinical syndromes

Nicola Toschi , Simone Lista , Filippo Baldacci , Enrica Cavedo , Henrik Zetterberg et al.
Neurobiology of Aging, 2019, 83, pp.42 - 53. ⟨10.1016/j.neurobiolaging.2019.08.032⟩
Journal articles hal-03488653v1
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Reduction of recruitment costs in preclinical AD trials. Validation of automatic pre-screening algorithm for brain amyloidosis

Manon Ansart , Stéphane Epelbaum , Geoffroy Gagliardi , Olivier Colliot , Didier Dormont et al.
Statistical Methods in Medical Research, 2019, pp.096228021882303. ⟨10.1177/0962280218823036⟩
Journal articles hal-01964942v2
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Applicability of in vivo staging of regional amyloid burden in a cognitively normal cohort with subjective memory complaints: the INSIGHT-preAD study

Fatemah A Sakr , Michel J Grothe , Enrica Cavedo , Irina Jelistratova , Marie-Odile Habert et al.
Alzheimer's Research and Therapy, 2019, 11, pp.15. ⟨10.1186/s13195-019-0466-3⟩
Journal articles hal-02006123v1
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Time for the systems-level integration of aging: Resilience enhancing strategies to prevent Alzheimer’s disease

Harald Hampel , Simone Lista , Christian Neri , Andrea Vergallo
Progress in Neurobiology, 2019, 181, pp.101662 -. ⟨10.1016/j.pneurobio.2019.101662⟩
Journal articles hal-03488187v1
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Biomarker-based prognosis for people with mild cognitive impairment (ABIDE): a modelling study

Ingrid S van Maurik , Stephanie J Vos , Isabelle Bos , Femke H Bouwman , Charlotte Teunissen et al.
The Lancet Neurology, 2019, 18 (11), pp.1034-1044. ⟨10.1016/S1474-4422(19)30283-2⟩
Journal articles inserm-02747461v1
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Differential default mode network trajectories in asymptomatic individuals at risk for Alzheimer's disease

Michel Thiebaut de Schotten , Hovagim Bakardjian , Habib Benali , Hugo Bertin , Joel Bonheur et al.
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 2019, 15 (7), pp.940-950. ⟨10.1016/j.jalz.2019.03.006⟩
Journal articles hal-02368904v1
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Plasma amyloid β 40/42 ratio predicts cerebral amyloidosis in cognitively normal individuals at risk for Alzheimer's disease

Andrea Vergallo , Lucile Mégret , Simone Lista , Enrica Cavedo , Henrik Zetterberg et al.
Alzheimer's and Dementia, 2019, 15, pp.764 - 775. ⟨10.1016/j.jalz.2019.03.009⟩
Journal articles hal-03484725v1
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Biomarker-Drug and Liquid Biopsy Co-development for Disease Staging and Targeted Therapy: Cornerstones for Alzheimer’s Precision Medicine and Pharmacology

Harald Hampel , Edward J Goetzl , Dimitrios Kapogiannis , Simone Lista , Andrea Vergallo et al.
Frontiers in Pharmacology, 2019, 10, pp.310. ⟨10.3389/fphar.2019.00310⟩
Journal articles hal-02095292v1
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Gray Matter Network Disruptions and Regional Amyloid Beta in Cognitively Normal Adults

Mara ten Kate , Pieter Jelle Visser , Hovagim Bakardjian , Frederik Barkhof , Sietske A.M. Sikkes et al.
Frontiers in Aging Neuroscience, 2018, 10, pp.67. ⟨10.3389/fnagi.2018.00067⟩
Journal articles hal-01757310v1
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Current state of Alzheimer’s fluid biomarkers

José Luis Molinuevo , Scott Ayton , Richard Batrla , Martin M Bednar , Tobias Bittner et al.
Acta Neuropathologica, 2018, 136 (6), pp.821-853. ⟨10.1007/s00401-018-1932-x⟩
Journal articles hal-01960281v1
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Revolution of Alzheimer Precision Neurology. Passageway of Systems Biology and Neurophysiology

Harald Hampel , Nicola Toschi , Claudio Babiloni , Filippo Baldacci , Keith L Black et al.
Journal of Alzheimer's Disease, 2018, 64 (s1), pp.S47 - S105. ⟨10.3233/jad-179932⟩
Journal articles hal-01910402v1
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No association of cortical amyloid load and EEG connectivity in older people with subjective memory complaints

Stefan Teipel , Hovagim Bakardjian , Gabriel Gonzalez-Escamilla , Enrica Cavedo , Sarah Weschke et al.
Neuroimage-Clinical, 2018, 17, pp.435-443. ⟨10.1016/j.nicl.2017.10.031⟩
Journal articles hal-01738143v1
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Analysis of shared heritability in common disorders of the brain

Verneri Anttila , Brenda Sullivan , Hilary Finucane , Walter Walters , Jose Bras et al.
Science, 2018, 360 (6395), eaap8757. ⟨10.1126/science.aap8757⟩
Journal articles cea-01870483v1
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Cognitive and neuroimaging features and brain β-amyloidosis in individuals at risk of Alzheimer's disease (INSIGHT-preAD): a longitudinal observational study

Bruno Dubois , Stéphane Epelbaum , Francis Nyasse , Hovagim Bakardjian , Geoffroy Gagliardi et al.
The Lancet Neurology, 2018, 17 (4), pp.335 - 346. ⟨10.1016/S1474-4422(18)30029-2⟩
Journal articles hal-01777834v1

Evaluation of amyloid status in a cohort of elderly individuals with memory complaints: validation of the method of quantification and determination of positivity thresholds

Marie-Odile Marie , Hugo Bertin , Mickael Labit , Mamadou Diallo , Sullivan Marie et al.
Annals of Nuclear Medicine, 2018, 32 (2), pp.75 - 86. ⟨10.1007/s12149-017-1221-0⟩
Journal articles hal-01716483v1
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Blood-based biomarkers for Alzheimer disease: mapping the road to the clinic

Harald Hampel , Sid O'Bryant , José L Molinuevo , Henrik Zetterberg , Colin L. Masters et al.
Nature Reviews Neurology, 2018, 14 (11), pp.639-652. ⟨10.1038/s41582-018-0079-7⟩
Journal articles hal-01972372v1
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Preclinical effects of APOE ε4 on cerebrospinal fluid Aβ42 concentrations

Ronald Lautner , Philip S Insel , Tobias Skillbäck , Bob Olsson , Mikael Landén et al.
Alzheimer's Research and Therapy, 2017, 9, pp.87. ⟨10.1186/s13195-017-0313-3⟩
Journal articles hal-01629381v1
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Preclinical Alzheimer's disease: a systematic review of the cohorts underlying the concept

Stéphane Epelbaum , Rémy Genthon , Enrica Cavedo , Marie Habert , Foudil Lamari et al.
Alzheimer's and Dementia, 2017, 13 (4), pp.454-467. ⟨10.1016/j.jalz.2016.12.003⟩
Journal articles hal-01672859v1
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Reduced basal forebrain atrophy progression in a randomized Donepezil trial in prodromal Alzheimer's disease

Enrica Cavedo , Michel J Grothe , Olivier Colliot , Simone Lista , Marie Chupin et al.
Scientific Reports, 2017, 7 (1), pp.11706. ⟨10.1038/s41598-017-09780-3⟩
Journal articles hal-01589622v1
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Revolution of Resting-State Functional Neuroimaging Genetics in Alzheimer’s Disease

Patrizia A. Chiesa , Enrica Cavedo , Simone Lista , Paul M Thompson , Harald Hampel et al.
Trends in Neurosciences, 2017, ⟨10.1016/j.tins.2017.06.002⟩
Journal articles hal-01560182v1
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Two-level diagnostic classification using cerebrospinal fluid YKL-40 in Alzheimer's disease

Filippo Baldacci , Nicola Toschi , Simone Lista , Henrik Zetterberg , Kaj Blennow et al.
Alzheimer's and Dementia, 2017, ⟨10.1016/j.jalz.2017.01.021⟩
Journal articles hal-01496140v1
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Amyloidosis and neurodegeneration result in distinct structural connectivity patterns in mild cognitive impairment

Thomas Jacquemont , Fabrizio de Vico Fallani , Anne Bertrand , Stéphane Epelbaum , Alexandre Routier et al.
Neurobiology of Aging, 2017, ⟨10.1016/j.neurobiolaging.2017.03.023⟩
Journal articles hal-01518785v1
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Free and Cued Selective Reminding Test – accuracy for the differential diagnosis of Alzheimer's and neurodegenerative diseases: A large-scale biomarker-characterized monocenter cohort study (ClinAD)

Stéphane Epelbaum , Marc Teichmann , Dalila Samri , Marcel Levy Nogueira , Harald Hampel et al.
Alzheimer's and Dementia, 2017, 13 (8), pp.913 - 923. ⟨10.1016/j.jalz.2016.12.014⟩
Journal articles hal-01672862v1

The frequency and influence of dementia risk factors in prodromal Alzheimer's disease

Isabelle Bos , Stephanie Vos , Lutz Frölich , Johannes Kornhuber , Jens Wiltfang et al.
Neurobiology of Aging, 2017, 56, pp.33-40. ⟨10.1016/j.neurobiolaging.2017.03.034⟩
Journal articles hal-03623839v1
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A Precision Medicine Initiative for Alzheimer's disease: the road ahead to biomarker-guided integrative disease modeling.

Harald Hampel , Sid O’bryant , Stanley Durrleman , Erfan Younesi , Katrine Rojkova et al.
Climacteric, 2017, 20 (2), pp.107-118
Journal articles hal-01566281v1
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Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Rebecca Sims , Sven van Der Lee , Adam Naj , Céline Bellenguez , Nandini Badarinarayan et al.
Nature Genetics, 2017, 49 (9), pp.1373-1384. ⟨10.1038/ng.3916⟩
Journal articles inserm-02466466v1
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Reduced Regional Cortical Thickness Rate of Change in Donepezil-Treated Subjects With Suspected Prodromal Alzheimer’s Disease

Enrica Cavedo , Bruno Dubois , Olivier Colliot , Simone Lista , Bernard Croisile et al.
Journal of Clinical Psychiatry, 2016, ⟨10.4088/JCP.15m10413⟩
Journal articles hal-01388951v1

Predictors of cognitive decline and treatment response in a clinical trial on suspected prodromal Alzheimer's disease

Stefan J Teipel , Enrica Cavedo , Michel J Grothe , Simone Lista , Samantha Galluzzi et al.
Neuropharmacology, 2016, 108, pp.128-35
Journal articles hal-01372417v1
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Apolipoprotein E-dependent load of white matter hyperintensities in Alzheimer's disease: a voxel-based lesion mapping study

Katrin Morgen , Michael Schneider , Lutz Frölich , Heike Tost , Michael M. Plichta et al.
Alzheimer's Research and Therapy, 2015, 7, pp.27. ⟨10.1186/s13195-015-0111-8⟩
Journal articles hal-01256015v1
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Comparing biological markers of Alzheimer's disease across blood fraction and platforms: Comparing apples to oranges

Sid E. O'Bryant , Simone Lista , Robert A. Rissman , Melissa Edwards , Fan Zhang et al.
Alzheimer's and Dementia, 2015, 3, pp.27-34. ⟨10.1016/j.dadm.2015.12.003⟩
Journal articles hal-01250140v1

Donepezil decreases annual rate of hippocampal atrophy in suspected prodromal Alzheimer's disease

Bruno Dubois , Marie Chupin , Harald Hampel , Simone Lista , Enrica Cavedo et al.
Alzheimer's and Dementia, 2015, 11 (9), pp.1041-1049. ⟨10.1016/j.jalz.2014.10.003⟩
Journal articles hal-01249861v1
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Excess of rare coding variants in PLD3 in late-but not early-onset Alzheimer's disease

Eva C Schulte , Alexander Kurz , Panagiotis Alexopoulos , Harald Hampel , Annette Peters et al.
Human Genome Variation, 2015, 2, pp.14028. ⟨10.1038/hgv.2014.28⟩
Journal articles hal-01120238v1
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The road ahead to cure Alzheimer’s disease: development of biological markers and neuroimaging methods for prevention trials across all stages and target populations

Enrica Cavedo , Simone Lista , Zaven S Khachaturian , Paul S Aisen , Philippe Amouyel et al.
The Journal of prevention of Alzheimer's disease, 2014, 1 (3), pp.181-202. ⟨10.14283/jpad.2014.32⟩
Journal articles hal-01098836v1

Perspective on future role of biological markers in clinical therapy trials of Alzheimer's disease: a long-range point of view beyond 2020

Harald Hampel , Simone Lista , Stefan J Teipel , Francesco Garaci , Robert Nisticò et al.
Biochemical Pharmacology, 2014, pp.426-49
Journal articles hal-01098832v1

Validation of AclarusDx™, a blood-based transcriptomic signature for the diagnosis of Alzheimer's disease.

Pascale Fehlbaum-Beurdeley , Olivier Sol , Laurent Désiré , Jacques Touchon , Thierry Dantoine et al.
Journal of Alzheimer's Disease, 2012, 32 (1), pp.169-181. ⟨10.3233/JAD-2012-120637⟩
Journal articles hal-01325482v1

Validation of AclarusDx™, a blood-based transcriptomic signature for the diagnosis of Alzheimer's disease.

Pascale Fehlbaum-Beurdeley , Olivier Sol , Laurent Désiré , Jacques Touchon , Thierry Dantoine et al.
Journal of Alzheimer's Disease, 2012, 32 (1), pp.169-81. ⟨10.3233/JAD-2012-120637⟩
Journal articles hal-00727243v1

Using support vector machines with multiple indices of diffusion for automated classification of mild cognitive impairment.

Laurence O'Dwyer , Franck Lamberton , Arun L W Bokde , Michael Ewers , Yetunde O Faluyi et al.
PLoS ONE, 2012, 7, pp.e32441
Journal articles hal-01164652v1

Sexual dimorphism in healthy aging and mild cognitive impairment: a DTI study.

Laurence O'Dwyer , Franck Lamberton , Arun L W Bokde , Michael Ewers , Yetunde O Faluyi et al.
PLoS ONE, 2011, 7 (7), pp.e37021
Journal articles hal-01164673v1

Multiple indices of diffusion identifies white matter damage in mild cognitive impairment and Alzheimer's disease.

Laurence O'Dwyer , Franck Lamberton , Arun L W Bokde , Michael Ewers , Yetunde O Faluyi et al.
PLoS ONE, 2010, 6 (6), pp.e21745
Journal articles hal-01157540v1
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Total and Phosphorylated Tau Protein as Biological Markers of Alzheimer's Disease

Harald Hampel , Kaj Blennow , Leslie M. Shaw , Yvonne C. Hoessler , Henrik Zetterberg et al.
Experimental Gerontology, 2009, 45 (1), pp.30. ⟨10.1016/j.exger.2009.10.010⟩
Journal articles hal-00547645v1
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White matter hyperintensities and medial temporal lobe atrophy in clinical subtypes of mild cognitive impairment: the DESCRIPA study

Laura van de Pol , Frans Verhey , Giovanni Frisoni , Magda Tsolaki , Panagiota Papapostoulou et al.
Journal of Neurology, Neurosurgery and Psychiatry, 2009, 80 (10), pp.1069. ⟨10.1136/jnnp.2008.158881⟩
Journal articles hal-00552719v1
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Validation of Alzheimer's disease CSF and Plasma Biological Markers The Multi-Center Reliability Study of the Pilot European Alzheimer's Disease Neuroimaging Initiative (E-ADNI)

Katharina Buerger , Giovanni B. Frisoni , Olga Uspenskaya , Michael Ewers , Henrik Zetterberg et al.
Experimental Gerontology, 2009, 44 (9), pp.579. ⟨10.1016/j.exger.2009.06.003⟩
Journal articles hal-00510618v1
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Blood-based Biomarkers of Microvascular Pathology in Alzheimer's disease

Michael Ewers , Michelle M. Mielke , Harald Hampel
Experimental Gerontology, 2009, 45 (1), pp.75. ⟨10.1016/j.exger.2009.09.005⟩
Journal articles hal-00547642v1

P3-324: CONCURRENT EEG/FMRI NETWORK DYNAMICS ALTERATIONS IN COGNITIVELY INTACT INDIVIDUALS AT RISK FOR ALZHEIMER'S DISEASE

Patrizia Andrea Chiesa , Giuseppe Spinelli , Denis Schwartz , Simone Lista , Marie-Claude Potier et al.
AAIC'2019 Alzheimer’s Association International Conference, Jul 2019, Los Angeles, United States. pp.P1062-P1063, ⟨10.1016/j.jalz.2019.06.3356⟩
Conference papers hal-03006234v1

P3-110: PRECLINICAL ALZHEIMER'S DISEASE: WHICH EEG BIOMARKERS FOR PRECISION MEDICINE?

Claudio Babiloni , Susanna Lopez , Claudio del Percio , Giuseppe Noce , Maria Teresa Pascarelli et al.
AAIC'2019 Alzheimer’s Association International Conference, Jul 2019, Los Angeles, United States. pp.P972-P972, ⟨10.1016/j.jalz.2019.06.3138⟩
Conference papers hal-03006232v1

P4-027: EVIDENCE FOR COGNITIVE COMPENSATION IN EARLY AMYLOIDOSIS IN HIGH-PERFORMING HEALTHY ELDERLY AT RISK FOR ALZHEIMER'S DISEASE

Hovagim Bakardjian , Giuseppe Spinelli , Nathalie George , Denis Schwartz , Harald Hampel et al.
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