Hersen Pascal

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Publications

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Optogenetic control of pheromone gradients reveals functional limits of mating behavior in budding yeast

Alvaro Banderas , Maud Hofmann , Céline Cordier , Matthias Le Bec , M Carolina Elizondo-Cantú et al.

Life Science Alliance, 2025, 8 (6), ⟨10.26508/lsa.202403078⟩

Article dans une revue hal-04789573v1
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Amplitude-Modulated Singular Value Decomposition for Ultrafast Ultrasound Imaging of Gas Vesicles

Ge Zhang , Mathis Vert , Mohamed Nouhoum , Esteban Rivera , Nabil Haidour et al.

IEEE Transactions on Medical Imaging, 2025, 44 (8), pp.3490-3501. ⟨10.1109/TMI.2025.3565023⟩

Article dans une revue hal-05342227v1
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Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability

Fabien Duveau , Céline Cordier , Lionel Chiron , Matthias Le Bec , Sylvain Pouzet et al.

eLife, 2024, 12, pp.RP88750. ⟨10.7554/eLife.88750⟩

Article dans une revue hal-04799234v1
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Prediction of strain level phage–host interactions across the Escherichia genus using only genomic information

Baptiste Gaborieau , Hugo Vaysset , Florian Tesson , Inès Charachon , Nicolas Dib et al.

Nature Microbiology, 2024, 9 (11), pp.2847-2861. ⟨10.1038/s41564-024-01832-5⟩

Article dans une revue hal-04781608v1
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Optogenetic spatial patterning of cooperation in yeast populations

Matthias Le Bec , Sylvain Pouzet , Céline Cordier , Simon Barral , Vittore Scolari et al.

Nature Communications, 2024, 15 (1), pp.75. ⟨10.1038/s41467-023-44379-5⟩

Article dans une revue hal-04288752v2
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Optogenetic control of beta-carotene bioproduction in yeast across multiple lab-scales

Sylvain Pouzet , Jessica Cruz-Ramón , Matthias Le Bec , Céline Cordier , Alvaro Banderas et al.

Frontiers in Bioengineering and Biotechnology, 2023, 11, pp.1085268. ⟨10.3389/fbioe.2023.1085268⟩

Article dans une revue hal-04247146v1
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Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability

Fabien Duveau , Céline Cordier , Lionel Chiron , Matthias Lebec , Sylvain Pouzet et al. Article dans une revue hal-04288775v1
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CyberSco.Py an open-source software for event-based, conditional microscopy

Lionel Chiron , Matthias Le Bec , Céline Cordier , Sylvain Pouzet , Dimitrije Milunov et al.

Scientific Reports, 2022, 12 (1), pp.11579. ⟨10.1038/s41598-022-15207-5⟩

Article dans une revue hal-03761554v1
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Autonomous and Assisted Control for Synthetic Microbiology

Alvaro Banderas , Matthias Le Bec , Céline Cordier , Pascal Hersen

International Journal of Molecular Sciences, 2020, 21 (23), pp.9223. ⟨10.3390/ijms21239223⟩

Article dans une revue hal-03083194v1
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Observing Nutrient Gradients, Gene Expression and Growth Variation Using the "Yeast Machine" Microfluidic Device

Zoran Marinkovic , Clément Vulin , Mislav Acman , Xiaohu Song , Jean Di Meglio et al.

Bio-protocol , 2020, 10 (13), ⟨10.21769/BioProtoc.3668⟩

Article dans une revue hal-03083179v1
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The Promise of Optogenetics for Bioproduction: Dynamic Control Strategies and Scale-Up Instruments

Sylvain Pouzet , Alvaro Banderas , Matthias Le Bec , Thomas Lautier , Gilles Truan et al.

Bioengineering, 2020, 7 (4), pp.151. ⟨10.3390/bioengineering7040151⟩

Article dans une revue (article de synthèse) hal-03083199v1
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Rational programming of history-dependent logic in cellular populations

Ana Zúñiga , Sarah Guiziou , Pauline Mayonove , Zachary Ben Meriem , Miguel Camacho et al.

Nature Communications, 2020, 11 (1), pp.4758. ⟨10.1038/s41467-020-18455-z⟩

Article dans une revue inserm-02952457v1

Enrichment of persisters enabled by a ß-lactam-induced filamentation method reveals their stochastic single-cell awakening

Etthel Windels , Zacchari Ben Meriem , Taiyeb Zahir , Kevin Verstrepen , Pascal Hersen et al.

Communications Biology, 2019, 2 (1), pp.426. ⟨10.1038/s42003-019-0672-3⟩

Article dans une revue hal-03761734v1
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Hyperosmotic Stress Response Memory is Modulated by Gene Positioning in Yeast

Zacchari Ben Meriem , Yasmine Khalil , Pascal Hersen , Emmanuelle Fabre

Cells, 2019, 8 (6), pp.582. ⟨10.3390/cells8060582⟩

Article dans une revue hal-02331194v1
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A microfluidic device for inferring metabolic landscapes in yeast monolayer colonies

Zoran Marinkovic , Clément Vulin , Mislav Acman , Xiaohu Song , Jean-Marc Di Meglio et al.

eLife, 2019, 8, ⟨10.7554/eLife.47951⟩

Article dans une revue hal-02331190v1
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Identification of individual cells from z-stacks of bright-field microscopy images

Jean-Baptiste Lugagne , Srajan Jain , Pierre Ivanovitch , Zacchary Ben Meriem , Clément Vulin et al.

Scientific Reports, 2018, 8 (1), pp.11455. ⟨10.1038/s41598-018-29647-5⟩

Article dans une revue hal-01898065v1
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Assembly and Characterizations of Bifunctional Fluorescent and Magnetic Microneedles Displaying Length Tunability over One Decade

Jean-Baptiste Lugagne , Gwennhaël Brackx , Emek Seyrek , Sophie Nowak , Yann Sivry et al.

Advanced Functional Materials, 2017, 27 (31), pp.1700362. ⟨10.1002/adfm.201700362⟩

Article dans une revue hal-02342490v1

Long-range self-organization of cytoskeletal myosin II filament stacks

Shiqiong Hu , Kinjal Dasbiswas , Zhenhuan Guo , Yee-Han Tee , Visalatchi Thiagarajan et al.

Nature Cell Biology, 2017, 19 (2), pp.133-141. ⟨10.1038/ncb3466⟩

Article dans une revue hal-03761727v1
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Balancing a genetic toggle switch by real-time feedback control and periodic forcing

Jean-Baptiste Lugagne , Sebastián Sosa Carrillo , Melanie Kirch , Agnes Köhler , Gregory Batt et al.

Nature Communications, 2017, 8 (1), pp.1-8. ⟨10.1038/s41467-017-01498-0⟩

Article dans une revue hal-01666980v1
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Long-term tracking of budding yeast cells in brightfield microscopy: CellStar and the Evaluation Platform

Cristian Versari , Szymon Stoma , Kirill Batmanov , Artémis Llamosi , Filip Mroz et al.

Journal of the Royal Society Interface, 2017, 14 (127), pp.32. ⟨10.1098/rsif.2016.0705⟩

Article dans une revue hal-01547623v1

Extracellular Vesicle Production Loaded with Nanoparticles and Drugs in a Trade-off between Loading, Yield and Purity: Towards a Personalized Drug Delivery System

Max Piffoux , Amanda Silva , Jean-Baptiste Lugagne , Pascal Hersen , Claire Wilhelm et al.

Advanced Biosystems, 2017, 1 (5), pp.1700044. ⟨10.1002/adbi.201700044⟩

Article dans une revue hal-03761731v1
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Age-Related Changes in Locomotor Performance Reveal a Similar Pattern for Caenorhabditis elegans, Mus domesticus, Canis familiaris, Equus caballus, and Homo sapiens

Adrien Marck , Geoffroy C.B. Berthelot , Vincent Foulonneau , Andy Marc , Juliana Antero et al.

Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 2016, 72 (4), pp.455-463. ⟨10.1093/gerona/glw136⟩

Article dans une revue hal-01792239v1

What population reveals about individual cell identity: Single-cell parameter estimation of models of gene expression in yeast

Artémis Llamosi , Andres Gonzalez , Cristian Versari , Eugenio Cinquemani , Giancarlo Ferrari-Trecate et al.

PLoS Computational Biology, 2016, 12 (2), pp.e1004706. ⟨10.1371/journal.pcbi.1004706⟩

Article dans une revue hal-01248298v1
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Out-of-equilibrium stationary states, percolation, and subcritical instabilities in a fully nonconservative system

Mathieu Génois , Pascal Hersen , Eric Bertin , Sylvain Courrech Du Pont , Guillaume Grégoire

Physical Review E , 2016, 94 (4), pp.042101. ⟨10.1103/physreve.94.042101⟩

Article dans une revue hal-02001608v3
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Combining Spinach-tagged RNA and gene localization to image gene expression in live yeast

David Guet , Laura Burns , Suman Maji , Jérôme Boulanger , Pascal Hersen et al.

Nature Communications, 2015, 6, pp.8882. ⟨10.1038/ncomms9882⟩

Article dans une revue hal-01725192v1

Structured illumination microscopy reveals focal adhesions are composed of linear subunits

Shiqiong Hu , Yee-Han Tee , Alexandre Kabla , Ronen Zaidel-Bar , Alexander Bershadsky et al.

Cytoskeleton, 2015, 72 (5), pp.235-245. ⟨10.1002/cm.21223⟩

Article dans une revue istex hal-03761721v1

Growing Yeast into Cylindrical Colonies

Clément Vulin , Jean-Marc Di Meglio , Ariel B. Lindner , Adrian Daerr , Andrew Murray et al.

Biophysical Journal, 2014, 106 (10), pp.2214-2221. ⟨10.1016/j.bpj.2014.02.040⟩

Article dans une revue hal-03761718v1

In vivo measurement of signaling cascade dynamics

Megan Mcclean , Pascal Hersen , Sharad Ramanathan

Cell Cycle, 2014, pp.373-376. ⟨10.4161/cc.8.3.7450⟩

Article dans une revue hal-03761747v1

High transcript levels of heat-shock genes are associated with shorter lifespan of Caenorhabditis elegans

X. Manière , A. Krisko , F.X. Pellay , J.-M. Di Meglio , Pascal Hersen et al.

Experimental Gerontology, 2014, 60 (11), pp.12-17. ⟨10.1016/j.exger.2014.09.005⟩

Article dans une revue hal-03761717v1

Severe osmotic compression triggers a slowdown of intracellular signaling, which can be explained by molecular crowding.

Agnès Miermont , François Waharte , Shiqiong Hu , Megan Nicole Mcclean , Samuel Bottani et al.

Proceedings of the National Academy of Sciences of the United States of America, 2013, 110 (14), pp.5725-30. ⟨10.1073/pnas.1215367110⟩

Article dans une revue hal-00817393v1
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An agent-based model of dune interactions produces the emergence of patterns in deserts

Mathieu Génois , Sylvain Courrech Du Pont , Pascal Hersen , Guillaume Grégoire

Geophysical Research Letters, 2013, 40, pp.3909. ⟨10.1002/grl.50757⟩

Article dans une revue hal-00759289v2
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Spatial structuring and size selection as collective behaviours in an agent-based model for barchan fields.

Mathieu Génois , Pascal Hersen , Sylvain Courrech Du Pont , Guillaume Grégoire

The European Physical Journal B: Condensed Matter and Complex Systems, 2013, 86 (11), pp.447. ⟨10.1140/epjb/e2013-40710-2⟩

Article dans une revue istex hal-00869412v1

Micro-patterned porous substrates for cell-based assays

Fanny Evenou , Jean-Marc Di Meglio , Benoit Ladoux , Pascal Hersen

Lab on a Chip, 2012, 12 (9), pp.1717. ⟨10.1039/C2LC20696J⟩

Article dans une revue hal-03761704v1
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Long-term model predictive control of gene expression at the population and single-cell levels

Jannis Uhlendorf , Agnès Miermont , Thierry Delaveau , Gilles Charvin , Francois Fages et al.

Proceedings of the National Academy of Sciences of the United States of America, 2012, 109 (35), pp.14271-14276. ⟨10.1073/pnas.1206810109⟩

Article dans une revue hal-01528440v1

Emerging modes of collective cell migration induced by geometrical constraints

Sri Ram Krishna Vedula , Man Chun Leong , Tan Lei Lai , Pascal Hersen , Alexandre Kabla et al.

Proceedings of the National Academy of Sciences of the United States of America, 2012, 109 (32), pp.12974-12979. ⟨10.1073/pnas.1119313109⟩

Article dans une revue hal-03761712v1

Locomotion Control of Caenorhabditis elegans through Confinement

Félix Lebois , Pascal Sauvage , Charlotte Py , Olivier Cardoso , Benoît Ladoux et al.

Biophysical Journal, 2012, 102 (12), pp.2791-2798. ⟨10.1016/j.bpj.2012.04.051⟩

Article dans une revue hal-03761705v1

Cell crawling mediates collective cell migration to close undamaged epithelial gaps

Ester Anon , Xavier Serra-Picamal , Pascal Hersen , Nils Gauthier , Michael Sheetz et al.

Proceedings of the National Academy of Sciences of the United States of America, 2012, 109 (27), pp.10891-10896. ⟨10.1073/pnas.1117814109⟩

Article dans une revue hal-03761707v1

Evidence of a large-scale mechanosensing mechanism for cellular adaptation to substrate stiffness

Léa Trichet , Jimmy Le Digabel , Rhoda Hawkins , Sri Ram Krishna Vedula , Mukund Gupta et al.

Proceedings of the National Academy of Sciences of the United States of America, 2012, 109 (18), pp.6933-6938. ⟨10.1073/pnas.1117810109⟩

Article dans une revue hal-03761708v1

Push it, pull it

Pascal Hersen , Benoît Ladoux

Nature, 2011, pp.340-341. ⟨10.1038/470340a⟩

Article dans une revue istex hal-03761744v1

The Dynamical Systems Properties of the HOG Signaling Cascade

Agnès Miermont , Jannis Uhlendorf , Megan Mcclean , Pascal Hersen

Journal of Signal Transduction, 2011, 2011, pp.1-12. ⟨10.1155/2011/930940⟩

Article dans une revue hal-03761696v1

Magnetic micropillars as a tool to govern substrate deformations

Jimmy Le Digabel , Nicolas Biais , Jérôme Fresnais , Jean-François Berret , Pascal Hersen et al.

Lab on a Chip, 2011, 11 (15), ⟨10.1039/C1LC20263D⟩

Article dans une revue hal-01378197v1

Towards Real-Time Control of Gene Expression: in silico Analysis*

Jannis Uhlendorf , Pascal Hersen , Gregory Batt

IFAC Proceedings Volumes, 2011, 44 (1), pp.14844-14850. ⟨10.3182/20110828-6-IT-1002.02614⟩

Article dans une revue hal-03761737v1

Mechanics of cell spreading within 3D-micropatterned environments

Marion Ghibaudo , Jean-Marc Di Meglio , Pascal Hersen , Benoit Ladoux

Lab on a Chip, 2011, 11 (5), pp.805-812. ⟨10.1039/C0LC00221F⟩

Article dans une revue hal-03761693v1

Running Worms: C. elegans Self-Sorting by Electrotaxis

Xavier Manière , Félix Lebois , Ivan Matic , Benoit Ladoux , Jean-Marc Di Meglio et al.

PLoS ONE, 2011, 6 (2), pp.e16637. ⟨10.1371/journal.pone.0016637⟩

Article dans une revue hal-03761699v1

Polygon formation and surface flow on a rotating fluid surface

R. Bergmann , L. Tophøj , T. Homan , P. Hersen , A. Andersen et al.

Journal of Fluid Mechanics, 2011, 679, pp.415-431. ⟨10.1017/jfm.2011.152⟩

Article dans une revue hal-03761702v1

Strength Dependence of Cadherin-Mediated Adhesions

Benoit Ladoux , Ester Anon , Mireille Lambert , Aleksandr Rabodzey , Pascal Hersen et al.

Biophysical Journal, 2010, 98 (4), pp.534-542. ⟨10.1016/j.bpj.2009.10.044⟩

Article dans une revue hal-03761686v1

Formation and stability of transverse and longitudinal sand dunes

Erwan Reffet , Sylvain Courrech Du Pont , Pascal Hersen , Stéphane Douady

Geology, 2010, 38 (6), pp.491-494. ⟨10.1130/G30894.1⟩

Article dans une revue hal-03761691v1

Traction forces exerted by epithelial cell sheets

Alexandre Saez , Ester Anon , Marion Ghibaudo , Olivia Du Roure , Jean-Marc Di Meglio et al.

Journal of Physics: Condensed Matter, 2010, 22 (19), pp.194119. ⟨10.1088/0953-8984/22/19/194119⟩

Article dans une revue hal-03761689v1
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Substrate topography induces a cross-over from 2D to 3D behavior in fibroblast migration

Marion Ghibaudo , Léa Trichet , Jimmy Le Digabel , Alain Richert , Pascal Hersen et al.

Biophysical Journal, 2009, 97 (1), pp.357-368. ⟨10.1016/j.bpj.2009.04.024⟩

Article dans une revue hal-00410702v1

Dynamic analysis of cell signalling

Pascal Hersen , Megan Mcclean , Sharad Ramanathan

Médecine/Sciences, 2008, 24 (12), pp.1020-1022. ⟨10.1051/medsci/200824121020⟩

Article dans une revue (article de synthèse) hal-03761748v1

Signal processing by the HOG MAP kinase pathway

Pascal Hersen , Megan Nicole Mcclean , Lakshminarayanan Mahadevan , Sharad Ramanathan

Proceedings of the National Academy of Sciences of the United States of America, 2008, 105 (20), pp.7165-7170. ⟨10.1073/pnas.0710770105⟩

Article dans une revue hal-00321259v1
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Genetic drift at expanding frontiers promotes gene segregation

Oskar Hallatschek , Pascal Hersen , Sharad Ramanathan , David R. Nelson

Proceedings of the National Academy of Sciences of the United States of America, 2007, 104, pp.19926-19930. ⟨10.1073/pnas.0710150104⟩

Article dans une revue hal-00321262v1
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Polygons on a Rotating Fluid Surface

Thomas Jansson , Martin Haspang , Kåre H. Jensen , Pascal Hersen , Tomas Bohr

Physical Review Letters, 2006, 96 (17), pp.174502. ⟨10.1103/PhysRevLett.96.174502⟩

Article dans une revue hal-00135893v1
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The song of the dunes as a self-synchronized instrument

Stéphane Douady , Audrey Manning , Pascal Hersen , Hicham Elbelrhiti , Suzie Protière et al.

Physical Review Letters, 2006, 97 (1), pp.018002. ⟨10.1103/PhysRevLett.97.018002⟩

Article dans une revue hal-00135892v1

Polygons on a Rotating Fluid Surface

Thomas Jansson , Martin Haspang , Kåre Jensen , Pascal Hersen , Tomas Bohr

Physical Review Letters, 2006, 96 (17), pp.174502. ⟨10.1103/PhysRevLett.96.174502⟩

Article dans une revue hal-03761666v1

Collision of barchan dunes as a mechanism of size regulation

Pascal Hersen , Stéphane Douady

Geophysical Research Letters, 2005, 32 (21), pp.L21403. ⟨10.1029/2005GL024179⟩

Article dans une revue hal-03761654v1

Flow effects on the morphology and dynamics of aeolian and subaqueous barchan dunes

Pascal Hersen

Journal of Geophysical Research: Earth Surface, 2005, 110 (F4), pp.n/a-n/a. ⟨10.1029/2004JF000185⟩

Article dans une revue hal-03761625v1

On the crescentic shape of barchan dunes

P. Hersen

The European Physical Journal B: Condensed Matter and Complex Systems, 2004, 37 (4), pp.507-514. ⟨10.1140/epjb/e2004-00087-y⟩

Article dans une revue hal-03761616v1

Corridors of barchan dunes: stability and size selection

Pascal Hersen , Ken H. Andersen , Hicham Elbelrhiti , Bruno Andreotti , Philippe Claudin et al.

Physical Review E : Statistical, Nonlinear, and Soft Matter Physics [2001-2015], 2004, 69 (1), pp.011304. ⟨10.1103/PhysRevE.69.011304⟩

Article dans une revue hal-00009356v1

Relevant Length Scale of Barchan Dunes

Pascal Hersen , Stéphane Douady , Bruno Andreotti

Physical Review Letters, 2002, 89 (26), pp.264301. ⟨10.1103/PhysRevLett.89.264301⟩

Article dans une revue hal-03761584v1

Towards Real-Time Control of Gene Expression at the Single Cell Level: A Stochastic Control Approach

Lakshmeesh Maruthi , Ilya Tkachev , Alfonso Carta , Eugenio Cinquemani , Pascal Hersen et al.

Computational Methods in Systems Biology, 8859, Springer International Publishing, pp.155-172, 2014, Lecture Notes in Computer Science, 978-3-319-12981-5. ⟨10.1007/978-3-319-12982-2_12⟩

Chapitre d'ouvrage hal-01096959v1

Microfluidic Platforms for Generating Dynamic Environmental Perturbations to Study the Responses of Single Yeast Cells

Anjali Bisaria , Pascal Hersen , Megan Mcclean

Yeast Genetics, 1205, Springer New York, pp.111-129, 2014, Methods in Molecular Biology, ⟨10.1007/978-1-4939-1363-3_8⟩

Chapitre d'ouvrage hal-03761742v1

In silico control of biomolecular processes

Jannis Uhlendorf , Agnès Miermont , Thierry Delaveau , Gilles Charvin , François Fages et al.

Mario A. Marchisio. Computational Methods in Synthetic Biology, 1244, Springer New York, pp.8, 2014, Methods in Molecular Biology, 978-1-4939-1877-5. ⟨10.1007/978-1-4939-1878-2_13⟩

Chapitre d'ouvrage hal-01104057v1

Micropatterned Porous Membranes for Combinatorial Cell-Based Assays

Clément Vulin , Fanny Evenou , Jean-Marc Di Meglio , Pascal Hersen

Micropatterning in Cell Biology Part C, 121, Elsevier, pp.155-169, 2014, Methods in Cell Biology, ⟨10.1016/b978-0-12-800281-0.00011-7⟩

Chapitre d'ouvrage hal-03761739v1

Dunes, the Collective Behaviour of Wind and Sand, or: Are Dunes Living Beings?

Stéphane Douady , Pascal Hersen

Morphogenesis, Springer Berlin Heidelberg, pp.107-118, 2011, ⟨10.1007/978-3-642-13174-5_6⟩

Chapitre d'ouvrage istex hal-03761749v1

Measuring In Vivo Signaling Kinetics in a Mitogen-Activated Kinase Pathway Using Dynamic Input Stimulation

Megan Mcclean , Pascal Hersen , Sharad Ramanathan

Yeast Genetic Networks, 734, Humana Press, pp.101-119, 2011, Methods in Molecular Biology, ⟨10.1007/978-1-61779-086-7_6⟩

Chapitre d'ouvrage hal-03761745v1

Towards real-time control of gene expression : controlling the hog signaling cascade

Jannis Uhlendorf , Samuel Bottani , François Fages , Pascal Hersen , Grégory Batt

Russ B. Altman; A. Keith Dunker; Lawrence Hunter; Tiffany A. Murray; Teri E. Klein. Biocomputing 2011, World Scientific, pp.338-349, 2010, ⟨10.1142/9789814335058_0035⟩

Chapitre d'ouvrage hal-03761738v1
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Morphogenese et Dynamique des Barchanes

Pascal Hersen

Dynamique des Fluides [physics.flu-dyn]. Université Paris-Diderot - Paris VII, 2004. Français. ⟨NNT : ⟩

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