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Hervé Guillou

CV Hervé Guillou Directeur de Recherche INRAE
162
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Researcher identifiers
  • IdHAL herve-guillou-inrae

Presentation

**Hervé Guillou (INRAE Toulouse)** **Born in Brest 13/09/1975** **herve.guillou@inrae.fr** **https://orcid.org/0000-0002-5363-9081** **Since 2018:** Member of unit board of directors (UMR1331 INRAE Toulouse) **Since 2016:** Senior investigator (DR) INRAE Toulouse, ToxAlim **Since 2009:** Group leader, “Integrative Toxicology and Metabolism”, INRAE ToxAlim **2008:** Junior investigator (CR) INRAE Toulouse, Molecular Pharmacology (Dir: Dr T. Pineau) **2004 –2007:** Post-doctoral scientist at Babraham Institute (Cambridge UK) Cell Signaling department (led by Dr L.R. Stephens et Dr P.T. Hawkins) **2000- 2004:** Assistant lecturer in biochemistry, Agrocampus Rennes **Degrees** **2014:** HDR – Toulouse University (France) **2004**: PhD in biochemistry and Cell Biology (Rennes University, France) **2000**: MSc in Physiology (Rennes University, France) **Teaching and training** **Teaching:** Pre-clinical Toxicology, Molecular endocrinology, Metabolism, Physiology and Hepatology, Lipid Biochemistry (MSc, University of Toulouse) **PhD Supervised (and current position):** Dr Simon Ducheix (PhD 2014; PI INSERM Nantes), Dr Alexia Buis (PhD 2018; started her own company), Dr Marion Régnier (PhD 2018; Post-doc, Institut Cochin), Dr Sarra Smati (MD, PhD 2019; Assistant Professor, University of Nantes), Dr Tiffany Fougeray (PhD 2020; Post-doc, Harvard Medical School), Dr Léonie Dopavogui (PhD 2021; Industry, Canada). **Post-doctoral scientist (and current position):** Dr Normand Podechard (2009-2011; Professor Rennes University of Pharmacy), Dr Alexandra Montagner (2011-2016; Principal Investigator INSERM Toulouse), Dr Anne Fougerat (2017-2021; Principal Investigator INRAE Toulouse), Dr Elena Piccinin (2022; Assistant Professor, University of Bari). **Fundings & Awards** Young scientist award from the French Society of Nutrition in 2014 Awards from the Francophone Society of Diabetes in 2015 and 2019 **Fundings:** ANR, ARC, INCA, SFD, SFN, AFEF, Occitanie, ANSES, FRM, EU (JPI) **Publications & Communication** 80 talks including selected oral communications at international meetings (Keystone Symposium; EMBO Meeting, EASD, EASL) 110 peer reviewed publications in international journals Full publication list available at [https://scholar.google.fr/citations?user=Toi0KcYAAAAJ&hl=fr](https://scholar.google.fr/citations?user=Toi0KcYAAAAJ&hl=fr)

Publications

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p110α-dependent hepatocyte signaling is critical for liver gene expression and its rewiring in MASLD

Marion Régnier , Arnaud Polizzi , Tiffany Fougeray , Anne Fougerat , Prunelle Perrier
Journal articles hal-04442467v1

Monoacylglycerol lipase reprograms hepatocytes and macrophages to promote liver regeneration

Manon Allaire , Rola Al-Sayegh , Morgane Mabire , Adel Hammoutene , Matthieu Siebert
JHEP Reports Innovation in Hepatology, 2023, 5 (8), pp.100794. ⟨10.1016/j.jhepr.2023.100794⟩
Journal articles hal-04178833v1

Obesity promotes fumonisin B1 hepatotoxicity

Léonie Dopavogui , Marion Régnier , Arnaud Polizzi , Quentin Ponchon , Sarra Smati
Science of the Total Environment, 2023, 891, pp.164436. ⟨10.1016/j.scitotenv.2023.164436⟩
Journal articles hal-04112262v1
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The interplay between dietary fatty acids and gut microbiota influences host metabolism and hepatic steatosis

Marc Schoeler , Sandrine Ellero-Simatos , Till Birkner , Jordi Mayneris-Perxachs , Lisa Olsson
Nature Communications, 2023, 14 (1), pp.5329. ⟨10.1038/s41467-023-41074-3⟩
Journal articles hal-04197137v1

Physiopathologie de la stéatose hépatique non-alcoolique (NAFLD)

Lucia Parlati , Marion Régnier , Catherine Postic , Hervé Guillou
Médecine des Maladies Métaboliques, 2023, in press, ⟨10.1016/j.mmm.2023.03.005⟩
Journal articles hal-04066670v1

C/EBPα Confers Dependence to Fatty Acid Anabolic Pathways and Vulnerability to Lipid Oxidative Stress–Induced Ferroptosis in FLT3 -Mutant Leukemia

Marie Sabatier , Rudy Birsen , Laura Lauture , Sarah Mouche , Paolo Angelino
Cancer Discovery, 2023, 13 (7), pp.1720-1747. ⟨10.1158/2159-8290.CD-22-0411⟩
Journal articles hal-04166110v1
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Prospective association between dietary pesticide exposure profiles and type 2 diabetes risk in the NutriNet-Santé cohort

Pauline Rebouillat , Rodolphe Vidal , Jean-Pierre Cravedi , Bruno Taupier-Letage , Laurent Debrauwer
Environmental Health, 2022, 21 (1), pp.57. ⟨10.1186/s12940-022-00862-y⟩
Journal articles hal-03689933v1
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NMR-based metabolic profiling and discrimination of wild tropical tunas by species, size category, geographic origin, and on-board storage condition

Nathalie Bodin , Aurélien Amiel , Edwin Fouché , Fany Sardenne , Emmanuel Chassot
Food Chemistry, 2022, 371, ⟨10.1016/j.foodchem.2021.131094⟩
Journal articles hal-03376705v1
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Zac1 and the Imprinted Gene Network program juvenile NAFLD in response to maternal metabolic syndrome

Marine Baptissart , Christine Bradish , Brie Jones , Evan Walsh , Jesse Tehrani
Hepatology, 2022, in press, ⟨10.1002/hep.32363⟩
Journal articles hal-03602068v1
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The hepatocyte insulin receptor is required to program the liver clock and rhythmic gene expression

Tiffany Fougeray , Arnaud Polizzi , Marion Régnier , Anne Fougerat , Sandrine Ellero-Simatos
Cell Reports, 2022, 39 (2), pp.110674. ⟨10.1016/j.celrep.2022.110674⟩
Journal articles hal-03647009v1

Monoacylglycerol lipase inhibition specifically in macrophages compromises liver regeneration by inducing interferon type 1 that negatively impacts on hepatocyte proliferation

Manon Allaire , Rola Al-Sayegh , Morgane Mabire , Matthieu Siebert , Mathilde Cadoux
Journal of Hepatology, 2022, 77, pp.S65
Journal articles hal-03765301v1
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Reduction in gut‐derived MUFAs via intestinal stearoyl‐CoA desaturase 1 deletion drives susceptibility to NAFLD and hepatocarcinoma

Simon Ducheix , Elena Piccinin , Claudia Peres , Oihane Garcia-Irigoyen , Justine Bertrand-Michel
Hepatology Communications, 2022, ⟨10.1002/hep4.2053⟩
Journal articles hal-03758408v1
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Integrative study of diet-induced mouse models of NAFLD identifies PPARα as a sexually dimorphic drug target

Sarra Smati , Arnaud Polizzi , Anne Fougerat , Sandrine Ellero-Simatos , Yuna Blum
Gut, 2022, 71 (4), pp.807-821. ⟨10.1136/gutjnl-2020-323323⟩
Journal articles hal-03215969v1
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ATGL-dependent white adipose tissue lipolysis controls hepatocyte PPARα activity

Anne Fougerat , Gabriele Schoiswohl , Arnaud Polizzi , Marion Régnier , Carina Wagner
Cell Reports, 2022, 39 (10), ⟨10.1016/j.celrep.2022.110910⟩
Journal articles hal-03695833v1
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Tissular Genomic Responses to Oral FB1 Exposure in Pigs

Léonie Dopavogui , Arnaud Polizzi , Anne Fougerat , Pascal Gourbeyre , Chloé Terciolo
Toxins, 2022, 14 (2), pp.83. ⟨10.3390/toxins14020083⟩
Journal articles hal-03609600v1

Evidence for constitutive microbiota-dependent short-term control of food intake in mice: Is there a link with inflammation, oxidative stress, endotoxemia, and Glp-1?

Selma Ben Fradj , Emmanuelle Nédélec , Juliette Salvi , Mélanie Fouesnard , Marine Huillet
Antioxidants and Redox Signaling, 2022, 37 (4-6), pp.349-369. ⟨10.1089/ars.2021.0095⟩
Journal articles hal-03594297v1
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Dual regulation of TxNIP by ChREBP and FoxO1 in liver

Bénédicte Noblet , Fadila Benhamed , Insug O-Sullivan , Wenwei Zhang , Gaelle Filhoulaud
iScience, 2021, 24 (3), pp.102218. ⟨10.1016/j.isci.2021.102218⟩
Journal articles hal-03176271v1
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The pregnane X receptor drives sexually dimorphic hepatic changes in lipid and xenobiotic metabolism in response to gut microbiota in mice

Sharon Barretto , Frédéric Lasserre , Marine Huillet , Marion Régnier , Arnaud Polizzi
Journal articles hal-03209709v1
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New targets for NAFLD

Lucia Parlati , Marion Régnier , Hervé Guillou , Catherine Postic
JHEP Reports Innovation in Hepatology, 2021, 3 (6), pp.100346. ⟨10.1016/j.jhepr.2021.100346⟩
Journal articles hal-03472343v1
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Endoplasmic reticulum stress controls iron metabolism through TMPRSS6 repression and hepcidin mRNA stabilization by RNA-binding protein HuR

Audrey Belot , Ophélie Gourbeyre , Anais Palin , Aude Rubio , Amélie Largounez
Haematologica, 2021, 106 (4), pp.1202-1206. ⟨10.3324/haematol.2019.237321⟩
Journal articles hal-02911817v1
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Proton NMR enables the absolute quantification of aqueous metabolites and lipid classes in unique mouse liver samples

Aurélien Amiel , Marie Tremblay-Franco , Roselyne Gautier , Simon Ducheix , Alexandra Montagner
Metabolites, 2020, 10 (1), 20 p. ⟨10.3390/metabo10010009⟩
Journal articles hal-02622894v1
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Peroxisome Proliferator-Activated Receptors and Their Novel Ligands as Candidates for the Treatment of Non-Alcoholic Fatty Liver Disease

Anne Fougerat , Alexandra Montagner , Nicolas Loiseau , Hervé Guillou , Walter Wahli
Cells, 2020, 9 (7), pp.1638. ⟨10.3390/cells9071638⟩
Journal articles hal-02899682v1
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Author correction: Dimorphic metabolic and endocrine disorders in mice lacking the constitutive androstane receptor

Céline Lukowicz , Sandrine Ellero-Simatos , Marion Régnier , Fabiana Oliviero , Frédéric Lasserre
Scientific Reports, 2020, 10 (1), ⟨10.1038/s41598-020-61226-5⟩
Journal articles hal-02627769v1
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Peroxisome Proliferator-Activated Receptors and Caloric Restriction-Common Pathways Affecting Metabolism, Health, and Longevity

Kalina Duszka , András Gregor , Hervé Guillou , Jürgen König , Walter Wahli
Journal articles hal-02904081v1
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Oxidative Stress in NAFLD: Role of Nutrients and Food Contaminants

Clémence Rives , Anne Fougerat , Sandrine Ellero-Simatos , Nicolas Loiseau , Hervé Guillou
Biomolecules, 2020, 10 (12), pp.1702. ⟨10.3390/biom10121702⟩
Journal articles hal-03100801v1
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Perinatal exposure to a dietary pesticide cocktail does not increase susceptibility to high-fat diet-induced metabolic perturbations at adulthood but modifies urinary and fecal metabolic fingerprints in C57Bl6/J mice

Lorraine Smith , Wendy Klement , Léonie Dopavogui , Frédéric de Bock , Frédéric Lasserre
Environment International, 2020, 144, pp.106010. ⟨10.1016/j.envint.2020.106010⟩
Journal articles hal-02912899v1
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Important Considerations for Sample Collection in Metabolomics Studies with a Special Focus on Applications to Liver Functions

Lorraine Smith , Joran Villaret-Cazadamont , Sandrine P Claus , Cécile Canlet , Hervé Guillou
Metabolites, 2020, 10 (3), pp.104. ⟨10.3390/metabo10030104⟩
Journal articles hal-02556806v1
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Hepatocyte-specific deletion of Pparα promotes NAFLD in the context of obesity

Marion Régnier , Arnaud Polizzi , Sarra Smati , Céline Lukowicz , Anne Fougerat
Scientific Reports, 2020, 10 (1), pp.6489. ⟨10.1038/s41598-020-63579-3⟩
Journal articles inserm-02875414v1
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Regulation of hepatokine gene expression in response to fasting and feeding: Influence of PPARa and insulin-dependent signaling in hepatocytes

Sarra Smati , Marion Régnier , Tiffany Fougeray , Arnaud Polizzi , Anne Fougerat
Diabetes & Metabolism, 2020, 46 (2), pp.129-136. ⟨10.1016/j.diabet.2019.05.005⟩
Journal articles hal-02402566v1
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The class 3 PI3K coordinates autophagy and mitochondrial lipid catabolism by controlling nuclear receptor PPARα

Anton Iershov , Ivan Nemazanyy , Chantal Alkhoury , Muriel Girard , Esther Barth
Nature Communications, 2019, 10 (1), 18 p. ⟨10.1038/s41467-019-09598-9⟩
Journal articles hal-02622186v1
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The protective role of liver X receptor (LXR) during fumonisin B1-induced hepatotoxicity

Marion Régnier , Arnaud Polizzi , Céline Lukowicz , Sarra Smati , Frédéric Lasserre
Archives of Toxicology, 2019, 93 (2), pp.505-517. ⟨10.1007/s00204-018-2345-2⟩
Journal articles hal-02619117v1
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Dimorphic metabolic and endocrine disorders in mice lacking the constitutive androstane receptor

Céline Lukowicz , Sandrine Ellero-Simatos , Marion Régnier , Fabiana Oliviero , Frédéric Lasserre
Scientific Reports, 2019, 9 (1), ⟨10.1038/s41598-019-56570-0⟩
Journal articles hal-02428712v1

Inhibition of monoacylglycerol lipase, an anti-inflammatory and antifibrogenic strategy in the liver

Aida Habib , Dina Chokr , Jinghong Wan , Pushpa Hegde , Morgane Mabire
Gut, 2019, 68 (3), pp.522-532. ⟨10.1136/gutjnl-2018-316137⟩
Journal articles hal-02963612v1
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Early life stress induces type 2 diabetes-like features in ageing mice

Hanna Ilchmann-Diounou , Maïwenn Olier , Corinne Lencina , Ambre Riba , Sharon Barretto
Brain, Behavior, and Immunity, 2019, 80, pp.452-463. ⟨10.1016/j.bbi.2019.04.025⟩
Journal articles hal-02627238v1
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Coelomocytes regulate starvation-induced fat catabolism and lifespan extension through the lipase LIPL-5 in Caenorhabditis elegans

Alexia Buis , Stéphanie Bellemin , Jérôme Goudeau , Léa Monnier , Nicolas Loiseau
Cell Reports, 2019, 28 (4), 1041-1049 + 6 p. ⟨10.1016/j.celrep.2019.06.064⟩
Journal articles hal-02628480v1

β-catenin oncogenic activation rewires fatty acid catabolism to fuel hepatocellular carcinoma

Alexandra Montagner , Laurent Le Cam , Hervé Guillou
Gut, 2019, 68 (2), pp.183-185. ⟨10.1136/gutjnl-2018-316557⟩
Journal articles hal-02448229v1
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Hepatic PPARalpha is critical in the metabolic adaptation to sepsis

Réjane Paumelle , Joël Haas , Nathalie Hennuyer , Eric Baugé , Yann Deleye
Journal of Hepatology, 2019, 70 (5), pp.963-973. ⟨10.1016/j.jhep.2018.12.037⟩
Journal articles inserm-02109735v1
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Selective Liver Estrogen Receptor Modulation Prevents Steatosis, Diabetes, and Obesity Through the Anorectic Growth Differentiation Factor 15 Hepatokine in Mice

Maeva Guillaume , Elodie Riant , Aurelie Fabre , Isabelle Raymond-Letron , Melissa Buscato
Hepatology Communications, 2019, 3 (7), pp.908-924. ⟨10.1002/hep4.1363⟩
Journal articles hal-02277993v1

Sphingolipid metabolism in non-alcoholic fatty liver diseases

Marion Régnier , Arnaud Polizzi , Hervé Guillou , Nicolas Loiseau
Biochimie, 2019, 159, pp.9-22. ⟨10.1016/j.biochi.2018.07.021⟩
Journal articles hal-02626541v1
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PGC-1 alpha induced browning promotes involution and inhibits lactation in mammary glands

Elena Piccinin , Annalisa Morgano , Claudia Peres , Annalisa Contursi , Justine Bertrand-Michel
Cellular and Molecular Life Sciences, 2019, 76 (24), pp.5011-5025. ⟨10.1007/s00018-019-03160-y⟩
Journal articles hal-02622923v1
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Depletion of gram-positive bacteria impacts hepatic biological functions during the light phase

Hui Yun Penny Oh , Sandrine Ellero-Simatos , Ravikumar Manickam , Nguan Soon Tan , Hervé Guillou
International Journal of Molecular Sciences, 2019, 20 (4), 28 p. ⟨10.3390/ijms20040812⟩
Journal articles hal-02620345v1
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Gene expression profiling reveals that PXR activation inhibits Hhepatic PPAR alpha activity and decreases FGF21 secretion in male C57Bl6/J mice

Sharon Barretto , Frédéric Lasserre , Anne Fougerat , Lorraine Smith , Tiffany Fougeray
International Journal of Molecular Sciences, 2019, 20 (15), ⟨10.3390/ijms20153767⟩
Journal articles hal-02617929v1
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Interaction between Hormone-Sensitive Lipase and ChREBP in Fat Cells Controls Insulin Sensitivity

Pauline Morigny , Marianne Houssier , Aline Mairal , Claire Ghilain , Etienne Mouisel
Nature Metabolism, 2019, 1 (1), pp.133-146. ⟨10.1038/s42255-018-0007-6⟩
Journal articles inserm-02150261v1
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Dual extraction of mRNA and lipids from a single biological sample

Normand Podechard , Simon Ducheix , Arnaud Polizzi , Frédéric Lasserre , Alexandra Montagner
Scientific Reports, 2018, 8 (1), pp.7019. ⟨10.1038/s41598-018-25332-9⟩
Journal articles hal-01794296v1
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Intracellular lipids are an independent cause of liver injury and chronic kidney disease in non alcoholic fatty liver disease-like context

Laure Monteillet , Monika Gjorgjieva , Marine Silva , Vincent Verzieux , Linda Imikirene
Molecular metabolism, 2018, 16, pp.100-115. ⟨10.1016/j.molmet.2018.07.006⟩
Journal articles inserm-02339561v1

40 Ar/ 39 Ar age of cryptochron C2r.2r-1 as recorded in a lava sequence within the Ko'olau volcano (Hawaii, USA)

Hervé Guillou , Vincent Scao , Sébastien Nomade
Quaternary Geochronology, 2018, 43, pp.91 - 101. ⟨10.1016/j.quageo.2017.10.005⟩
Journal articles hal-01806763v1
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Metabolic effects of a chronic dietary exposure to a low-dose oesticide cocktail in mice: Sexual dimorphism and role of the constitutive androstane receptor

Céline Lukowicz , Sandrine Ellero-Simatos , Marion Régnier , Arnaud Polizzi , Frédéric Lasserre
Environmental Health Perspectives, 2018, 126 (6), 18 p. ⟨10.1289/EHP2877⟩
Journal articles hal-02624889v1
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Complementary intestinal mucosa and microbiota responses to caloric restriction

Kalina Duszka , Sandrine Ellero-Simatos , Ghim Siong Ow , Marianne Defernez , Eeswari Paramalingam
Scientific Reports, 2018, 8, ⟨10.1038/s41598-018-29815-7⟩
Journal articles hal-02621482v1
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The histone demethylase Phf2 acts as a molecular checkpoint to prevent NAFLD progression during obesity

Julien Bricambert , Marie-Clotilde Alves-Guerra , Pauline Esteves , Carina Prip-Buus , Justine Bertrand-Michel
Nature Communications, 2018, 9 (1), ⟨10.1038/s41467-018-04361-y⟩
Journal articles hal-02122655v1

Insights into the role of hepatocyte PPARα activity in response to fasting

Marion Régnier , Arnaud Polizzi , Yannick Lippi , Edwin Fouché , Géraldine Michel
Molecular and Cellular Endocrinology, 2017, in press, ⟨10.1016/j.mce.2017.07.035⟩
Journal articles hal-01605514v1
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Dietary oleic acid regulates hepatic lipogenesis through a liver X receptor-dependent signaling

Simon Ducheix , Alexandra Montagner , Arnaud Polizzi , Frédéric Lasserre , Marion Régnier
PLoS ONE, 2017, 12 (7), ⟨10.1371/journal.pone.0181393⟩
Journal articles hal-01606929v1
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A Specific ChREBP and PPARα Cross-Talk Is Required for the Glucose-Mediated FGF21 Response

Alison Iroz , Alexandra Montagner , Fadila Benhamed , Françoise Levavasseur , Arnaud Polizzi
Cell Reports, 2017, 21 (2), pp.403 - 416. ⟨10.1016/j.celrep.2017.09.065⟩
Journal articles hal-01837159v1
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Identification of signaling pathways targeted by the food contaminant FB1: Transcriptome and kinome analysis of samples from pig liver and intestine

Marion Régnier , Pascal Gourbeyre , Philippe Pinton , Scott Napper , Joëlle Laffitte
Molecular Nutrition and Food Research, 2017, in press (12), 42 p. ⟨10.1002/mnfr.201700433⟩
Journal articles hal-01606651v1

Type 2 diabetes prevention through hormone sensitive lipase inhibition: elongase ELOVL6 at the center of attention

P. Morigny , M. Houssier , E. Mouisel , A. Mairal , S. Caspar-Bauguil
Diabetologia, 2017, 60, pp.S249
Journal articles hal-02624062v1

Selective activation of estrogen receptor alpha activation function-1 is sufficient to prevent obesity, steatosis, and insulin resistance in mouse

Maeva Guillaume , Sandra Handgraaf , Aurelie J Fabre , Isabelle Raymond-Letron , Elodie Riant
American Journal of Pathology, 2017, 187 (6), pp.1273-1287. ⟨10.1016/j.ajpath.2017.02.013⟩
Journal articles hal-01603827v1
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Glycerol-3-phosphate acyltransferase 2 expression modulates cell roughness and membrane permeability: An atomic force microscopy study

Elizabeth R. Cattaneo , Eduardo Prieto , Maria B. Garcia-Fabiani , Mauro A. Montanaro , Hervé Guillou
PLoS ONE, 2017, 12 (12), 18 p. ⟨10.1371/journal.pone.0189031⟩
Journal articles hal-02622165v1
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The gut microbiota: a major player in the toxicity of environmental pollutants?

Sandrine P. Claus , Hervé Guillou , Sandrine Ellero-Simatos
npj Biofilms and Microbiomes, 2016, 2, ⟨10.1038/npjbiofilms.2016.3⟩
Journal articles hal-01602371v1

Novel Grb14-Mediated Cross Talk between Insulin and p62/Nrf2 Pathways Regulates Liver Lipogenesis and Selective Insulin Resistance

Lucie Popineau , Lucille Morzyglod , Nadege Carre , Michele Cauzac , Pascale Bossard
Molecular and Cellular Biology, 2016, 36 (16), pp.2168 - 2181. ⟨10.1128/MCB.00170-16⟩
Journal articles hal-01602453v1
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Perilipin 5 fine-tunes lipid oxidation to metabolic demand and protects against lipotoxicity in skeletal muscle

Claire Laurens , Virginie Bourlier , Aline Mairal , Katie Louche , Pierre-Marie Badin
Scientific Reports, 2016, 6, ⟨10.1038/srep38310⟩
Journal articles hal-01605047v1
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Activation of the Constitutive Androstane Receptor induces hepatic lipogenesis and regulates Pnpla3 gene expression in a LXR-independent way

Alice Marmugi , Céline Lukowicz , Frédéric Lasserre , Alexandra Montagner , Arnaud Polizzi
Toxicology and Applied Pharmacology, 2016, 303, pp.90 - 100. ⟨10.1016/j.taap.2016.05.006⟩
Journal articles hal-01837194v1
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Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD

Alexandra Montagner , Arnaud Polizzi , Edwin Fouché , Simon Ducheix , Yannick Lippi
Gut, 2016, 65 (7), pp.1202-1214. ⟨10.1136/gutjnl-2015-310798⟩
Journal articles inserm-02339685v1
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Transcriptional control of physiological and pathological processes by the nuclear receptor PPAR beta/delta

Nguan Soon Tan , Manuel Vázquez-Carrera , Alexandra Montagner , Ming Keat Sng , Hervé Guillou
Progress in Lipid Research, 2016, 64, pp.98-122. ⟨10.1016/j.plipres.2016.09.001⟩
Journal articles hal-01594607v1
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Hepatic circadian clock oscillators and nuclear receptors integrate microbiome-derived signals

Alexandra Montagner , Agata Korecka , Arnaud Polizzi , Yannick Lippi , Yuna Blum
Scientific Reports, 2016, 6 (1), pp.1-14. ⟨10.1038/srep20127⟩
Journal articles hal-01482816v1
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Localizing the lipid products of PI3Kγ in neutrophils

Laura Norton , Yvonne Lindsay , Arnaud Deladeriere , Tamara Chessa , Hervé Guillou
Advances in Biological Regulation, 2016, 60, pp.36-45. ⟨10.1016/j.jbior.2015.10.005⟩
Journal articles hal-01602482v1
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Effects of pesticide mixtures in human and animal models: an update of the recent literature

Virginie Rizzati , O. Briand , Hervé Guillou , Laurence Gamet-Payrastre
Chemico-Biological Interactions, 2016, 254, pp.231-246. ⟨10.1016/j.cbi.2016.06.003⟩
Journal articles hal-02637756v1
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Intestinal PPAR gamma signalling is required for sympathetic nervous system activation in response to caloric restriction

Kalina Duszka , Alexandre Picard , Sandrine Ellero-Simatos , Jiapeng Chen , Marianne Defernez
Scientific Reports, 2016, 6, ⟨10.1038/srep36937⟩
Journal articles hal-01606898v1
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Glucocorticoid receptor-PPAR alpha axis in fetal mouse liver prepares neonates for milk lipid catabolism

Gianpaolo Rando , Chek Kun Tan , Nourhène Khaled , Alexandra Montagner , Nicolas Leuenberger
eLife, 2016, 5, 31 p. ⟨10.7554/eLife.11853⟩
Journal articles hal-01602433v1

The suppression of hepatic glucose production improves metabolism and insulin sensitivity in subcutaneous adipose tissue in mice

Sylvie Casteras , Aya Abdul-Wahed , Maud Soty , Fanny Vulin , Hervé Guillou
Diabetologia, 2016, 59 (12), pp.2645-2653. ⟨10.1007/s00125-016-4097-y⟩
Journal articles hal-01606287v1
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White-to-brite conversion in human adipocytes promotes metabolic reprogramming towards fatty acid anabolic and catabolic pathways

V Barquissau , D. Beuzelin , D. Pisani , G.E. Beranger , A. Mairal
Molecular metabolism, 2016, 5 (5), pp.352-365. ⟨10.1016/j.molmet.2016.03.002⟩
Journal articles hal-02134884v1
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Hepatic fasting-induced PPAR alpha activity does not depend on essential fatty acids

Arnaud Polizzi , Edwin Fouché , Simon Ducheix , Frédéric Lasserre , Alice Marmugi
International Journal of Molecular Sciences, 2016, 17 (10), pp.1624. ⟨10.3390/ijms17101624⟩
Journal articles hal-01476503v1
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Protective effects of n-6 fatty acids-enriched diet on intestinal ischaemia/reperfusion injury involve lipoxin A4 and its receptor

Thomas Gobbetti , Simon Ducheix , Pauline Le Faouder , Teresa Pérez-Berezo , Fabien Riols
British Journal of Pharmacology, 2015, 172 (3), pp.910-923. ⟨10.1111/bph.12957⟩
Journal articles hal-01601458v1
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New insights into the organ-specific adverse effects of fumonisin B1

Nicolas Loiseau , Arnaud Polizzi , Aude Dupuy , Nicole Therville , Mirindra Rakotonirainy
Archives of Toxicology, 2015, 89 (9), pp.1619-1629. ⟨10.1007/s00204-014-1323-6⟩
Journal articles hal-03331305v1

Effect of obesity and metabolic syndrome on plasma oxysterols and fatty acids in human

Marie Tremblay-Franco , Chiara Zerbinati , Antonio Pacelli , Giuseppina Palmaccio , Carla Lubrano
Steroids, 2015, 99 (Part B), pp.287-292. ⟨10.1016/j.steroids.2015.03.019⟩
Journal articles hal-02639945v1
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Combined QTL and selective sweep mappings with coding SNP annotation and cis-eQTL analysis revealed PARK2 and JAG2 as new candidate genes for adiposity regulation.

Pierre-François Roux , Simon Boitard , Anne Blum , Brian Parks , Alexandra Montagner
G3, 2015, 5, pp.517-529. ⟨10.1534/g3.115.016865⟩
Journal articles hal-01194040v1

Adverse effects of long-term exposure to bisphenol A during adulthood leading to hyperglycaemia and hypercholesterolemia in mice

Alice Marmugi , Frédéric Lasserre , Diane Beuzelin , Simon Ducheix , Laurence Huc
Toxicology, 2014, 325, pp.133-143. ⟨10.1016/j.tox.2014.08.006⟩
Journal articles hal-02641668v1
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A link between hepatic glucose production and peripheral energy metabolism via hepatokines.

Aya Abdul-Wahed , Amandine Gautier-Stein , Sylvie Casteras , Maud Soty , Damien Roussel
Molecular metabolism, 2014, 3 (5), pp.531-543. ⟨10.1016/j.molmet.2014.05.005⟩
Journal articles inserm-01350728v1

Essential fatty acids deficiency promotes lipogenic gene expression and hepatic steatosis through the liver X receptor.

Simon Ducheix , Alexandra Montagner , Arnaud Polizzi , Frédéric Lasserre , Alice Marmugi
Journal of Hepatology, 2013, 58 (5), pp.984-92. ⟨10.1016/j.jhep.2013.01.006⟩
Journal articles inserm-00872314v1

The liver X receptor: A master regulator of the gut-liver axis and a target for non alcoholic fatty liver disease

Simon Ducheix , Alexandra Montagner , Vassilia Theodorou , Laurent Ferrier , Hervé Guillou
Biochemical Pharmacology, 2013, 86 (1), pp.96 - 105. ⟨10.1016/j.bcp.2013.03.016⟩
Journal articles hal-02646839v1
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In vivo hepatic lipid quantification using MRS at 7 Tesla in a mouse model of glycogen storage disease type 1a

N. Ramamonjisoa , H. Ratiney , E. Mutel , Hervé Guillou , G. Mithieux
Journal of Lipid Research, 2013, 54 (7), pp.2010-2022. ⟨10.1194/jlr.D033399⟩
Journal articles hal-00847703v1

A systems biology approach to the hepatic role of the oxysterol receptor LXR in the regulation of lipogenesis highlights a cross-talk with PPARα.

Simon Ducheix , Normand Podechard , Frédéric Lasserre , Arnaud Polizzi , Aurélien Pommier
Biochimie, 2013, 95 (3), pp.556-67. ⟨10.1016/j.biochi.2012.09.028⟩
Journal articles inserm-00872582v1
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The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans

.F. Benhamed , Pd Denechaud , C Robichon , M Moldes , J Girard
Journal of Clinical Investigation, 2012, 122 (6), pp.2176-94. ⟨10.1172/JCI41636⟩
Journal articles hal-02649316v1
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GPCR activation of Ras and PI3Kc in neutrophils depends on PLCb2/b3 and the RasGEF RasGRP4

Sabine Suire Sabine , Charlotte Lécureuil , Karen Anderson E , George Damoulakis George , Izabella Niewczas Izabella
EMBO Journal, 2012, 31 (14), pp.3118-3129. ⟨10.1038/emboj.2012.167⟩
Journal articles hal-00776864v1
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Low Doses of Bisphenol A Induce Gene Expression Related to Lipid Synthesis and Trigger Triglyceride Accumulation in Adult Mouse Liver

Alice Marmugi , Simon Ducheix , Frédéric Lasserre , Arnaud Polizzi , Alain Paris
Hepatology, 2012, 55 (2), pp.395-407. ⟨10.1002/hep.24685⟩
Journal articles hal-01019497v1
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GW501516-activated PPARbeta/delta promotes liver fibrosis via p38-JNK MAPK-induced hepatic stellate cell proliferation.

Radina Kostadinova , Alexandra Montagner , Erwan Gouranton , Sébastien Fleury , Hervé Guillou
Cell & Bioscience, 2012, 2 (1), pp.34. ⟨10.1186/2045-3701-2-34⟩
Journal articles inserm-00763884v1
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ELOVL2 controls the level of n-6 28:5 and 30:5 fatty acids in testis, a prerequisite for male fertility and spermmaturation in mice

Damir Zadravec , Petr Tvrdik , Hervé Guillou , Rilchard Haslam , Tsutomu Kobayash
Journal of Lipid Research, 2011, 52 (2), pp.245-255. ⟨10.1194/jlr.M011346⟩
Journal articles hal-01137032v1
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Liver X Receptor: an oxysterol sensor and a major playerin the control of lipogenesis

Simon Ducheix , J.M.A. Lobaccaro , Pascal G.P. Martin , Hervé Guillou
Chemistry and Physics of Lipids, 2011, 164 (6), pp.500-14. ⟨10.1016/j.chemphyslip.2011.06.004⟩
Journal articles hal-02651993v1
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Cooperativity between Integrin Activation and Mechanical Stress Leads to Integrin Clustering.

Olivier Ali , Hervé Guillou , Olivier Destaing , Corinne Albiges-Rizo , Marc R. Block
Biophysical Journal, 2011, 100 (11), pp.2595-604. ⟨10.1016/j.bpj.2011.03.028⟩
Journal articles inserm-00605002v1

Regulation of LPCAT3 by LXR.

O. Demeure , Frédéric Lecerf , C. Duby , Colette Désert , S. Ducheix
Gene, 2011, 470 (1-2), pp.7-11. ⟨10.1016/j.gene.2010.09.002⟩
Journal articles hal-00729271v1

PI3K beta Plays a Critical Role in Neutrophil Activation by Immune Complexes

Suhasini Kulkarni , Cassian Sitaru , Zoltan Jakus , Karen E. Anderson , George Damoulakis
Science Signaling, 2011, 4 (168), pp.ra23. ⟨10.1126/scisignal.2001617⟩
Journal articles hal-02649985v1
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P-glycoprotein Dysfunction Contributes to HepaticSteatosis and Obesity in Mice

Magali Vignault-Foucaud , Zeina Soayfane , Cécile Menez-Berlioz , Justine Bertrand-Michel , Pascal G.P. Martin
PLoS ONE, 2011, 6 (9), pp.e23614
Journal articles hal-01137178v1
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Is Crohn's creeping fat an adipose tissue?

Isabelle Olivier , Vassilia Theodorou , Philippe Valet , Isabelle Castan-Laurell , Hervé Guillou
Inflammatory Bowel Diseases, 2011, 17 (3), pp.747-57. ⟨10.1002/ibd.21413⟩
Journal articles inserm-00617823v1
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P-glycoprotein Dysfunction Contributes to Hepatic Steatosis and Obesity in Mice

Magali Vignault-Foucaud , Zeina Soayfane , Cécile Menez-Berlioz , Justine Bertrand-Michel , Pascal Guy
PLoS ONE, 2011, 6 (9), ⟨10.1371/journal.pone.0023614⟩
Journal articles hal-02650319v1

Ablation of the very-long-chain fatty acid elongase ELOVL3 in mice leads to constrained lipid storage and resistance to diet-induced obesity

Damir Zadravec , Annelie Brolinson , Rachel M. Fisher , Claes Carneheim , Robert I. Csikasz
FASEB Journal, 2010, 24 (11), pp.4366 - 4377. ⟨10.1096/fj.09-152298⟩
Journal articles hal-02662422v1

ARAP3 binding to phosphatidylinositol-(3,4,5)-trisphosphate depends on N-terminal tandem PH domains and adjacent sequences

Helen E. Craig , John Coadwell , Hervé Guillou , Sonja Vermeren
Cellular Signalling, 2010, 22 (2), pp.257-264. ⟨10.1016/j.cellsig.2009.09.025⟩
Journal articles hal-02662592v1
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A minimal model for hepatic fatty acid balance during fasting: Application to PPAR alpha-deficient mice

Pierre Blavy , Florence Gondret , Hervé Guillou , Sandrine Lagarrigue , P.G.P. Martin
Journal of Theoretical Biology, 2009, 261 (2), pp.266. ⟨10.1016/j.jtbi.2009.07.025⟩
Journal articles hal-00559147v1

Identification of potential mechanisms of toxicity after di-(2-ethylhexyl)-phthalate (DEHP) adult exposure in the liver using a systems biology approach

Alexandre Eveillard , Frédéric Lasserre , M de Tayrac , Arnaud Polizzi , S Claus
Toxicology and Applied Pharmacology, 2009, 236 (3), pp.282-292. ⟨10.1016/j.taap.2009.02.008⟩
Journal articles hal-02662270v1

Liver X receptor alpha regulates fatty acid synthase expression in chicken.

O. Demeure , C. Duby , Colette Désert , S. Assaf , Dominique Hazard
Poultry Science, 2009, 88 (12), pp.2628-35. ⟨10.3382/ps.2009-00258⟩
Journal articles hal-00730008v1
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FSH-stimulated PTEN activity accounts for the lack of FSH mitogenic effect in prepubertal rat Sertoli cells

Joëlle Dupont , Astrid Musnier , Jérémy Decourtye , Thomas Boulo , Charlotte Lécureuil
Molecular and Cellular Endocrinology, 2009, 315 (1-2), pp.271. ⟨10.1016/j.mce.2009.09.016⟩
Journal articles hal-00547657v1
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Di-(2-ethylhexyl)-phthalate (DEHP) activates the Constitutive Androstane Receptor (CAR): a novel signalling pathway sensitive to phthalates

Alexandre Eveillard , Laila Mselli-Lakhal , Ariane Mogha , Frédéric Lasserre , Arnaud Polizzi
Biochemical Pharmacology, 2009, 77 (11), pp.1735. ⟨10.1016/j.bcp.2009.02.023⟩
Journal articles hal-00493499v1

Transcriptional regulation of hepatic fatty acid metabolism

Hervé Guillou , Pg Martin , Thierry Pineau
Sub-cellular biochemistry, 2008, 49, pp.3-47
Journal articles hal-02653666v1

Novel aspects of PPARα-mediated regulation of lipid and xenobiotic metabolism revealed through a nutrigenomic study

Pascal G.P. Martin , Hervé Guillou , Frédéric Lasserre , Sébastien Dejean , Annaig Lan
Hepatology, 2007, 45 (3), pp.767-777. ⟨10.1002/hep.21510⟩
Journal articles hal-00661808v1

Novel aspects of PPAR alpha-mediated regulation of lipid and xenobiotic metabolism revealed through a nutrigenomic study.

P.G.P. Martin , Hervé Guillou , F. Lasserre , S. Déjean , Annaig Lan
Hepatology, 2007, 45, pp.667-677
Journal articles hal-02659352v1
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Myristic acid increases $\Delta$6-desaturase activity in cultured rat hepatocytes

Sophie Jan , Hervé Guillou , Sabine d'Andrea , Stéphanie Daval , Monique Bouriel
Reproduction Nutrition Development, 2004, 44 (2), pp.131-140. ⟨10.1051/rnd:2004020⟩
Journal articles hal-00900482v1
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Conversion of hexadecanoic acid to hexadecenoic acid by rat delta 6-desaturase

Hervé Guillou , Vincent V. Rioux , Daniel D. Catheline , Jean-Noel J.-N. Thibault , Monique Bouriel
Journal of Lipid Research, 2003, 44 (3), pp.450-454. ⟨10.1194/jlr.C200019-JLR200⟩
Journal articles hal-02678861v1
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Although it is rapidly metabolized in cultured rat hepatocytes, lauric acid is used for protein acylation

Vincent V. Rioux , Stéphanie Daval , Hervé Guillou , Sophie Jan , Philippe P. Legrand
Reproduction Nutrition Development, 2003, 43 (5), pp.419-430. ⟨10.1051/rnd:2003036⟩
Journal articles hal-00900517v1

Effects of dietary fatty acids on the expression of an array of class II nuclear receptor target genes

P. Martin , Hervé Guillou , F. Lasserre , Cécile Calléja , Sophie Jan
Drug Metabolism Reviews, 2003, 35 (178), pp.89
Journal articles hal-02674247v1

The same rat delta 6-desaturase not only acts on 18- but also on 24-carbon fatty acids in very-long-chain polyunsaturated fatty acid biosynthesis

Sabine d'Andrea , Hervé Guillou , Sophie Jan , Daniel D. Catheline , Jean-Noel J.-N. Thibault
Biochemical Journal, 2002, 364, pp.49-55
Journal articles hal-02669429v1

Hydrolysis of beta-casein by gastric proteases. 1. Comparison of proteolytic action of bovine chymosin and pepsin A

Hervé Guillou , Guy Miranda , J.P. Pelissier
International Journal of Peptide and Protein Research, 1991, 37, pp.494-501
Journal articles hal-02708181v1
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Analyse quantitative des caséines dans le lait de vache par chromatographie liquide rapide d'échange d'ions (FPLC)

Hervé Guillou , G. Miranda , J.-P. Pelissier
Le Lait, 1987, 67 (2), pp.135-148
Journal articles hal-00929097v1

Analyse quantitative des caseines dans le lait de vache par chromatographie liquide rapide d'echange d'ions (FPLC)

Hervé Guillou , Guy Miranda , J.P. Pelissier
Lait, 1987, 67, pp.135-148
Journal articles hal-02719777v1

Analyse quantitative des caseines dans le lait de vache par chromatographie liquide rapide d'echanges d'ions (FPLC)

Hervé Guillou , Guy Miranda , J.P. Pelissier
Lait, 1987, 67 (2), pp.135-148
Journal articles hal-02721649v1

Methodes de dosage des proteines du lait de vache

Hervé Guillou , J.P. Pelissier , R. Grappin
Lait, 1986, 66, pp.143-175
Journal articles hal-02718097v1
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Méthodes de dosage des protéines du lait de vache

Hervé Guillou , J.P. Pelissier , R. Grappin
Le Lait, 1986, 66 (2), pp.143-175
Journal articles hal-00929062v1
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Apport de l'imagerie MS dans le domaine de la toxicologie alimentaire

Justine Ferey , Loic Mervant , Emilien Jamin , Fabrice Pierre , Françoise Guéraud
Journées annuelles du GDR-MSI, Jun 2024, Strasbourg (67), France
Conference papers hal-04634081v1

Effets d’une exposition alimentaire, périnatale et chronique alimentaire, à des doses réglementaires de glyphosate sur l’axe microbiote intestinal-intestin-foie

Lorraine Smith , Céline Martin , Sabrine Naimi , Beatrice Engelmann , Frédéric Lasserre
13ème congrès annuel de la Société Francophone de Santé et Environnement, Nov 2022, Valence, France
Conference papers hal-03775382v1

Sex dimorphic role of estrogen receptor a in physiological regulation of hepatic metabolism

Blandine Tramunt , Sarra Smati , Naia Grandgeorge , Anne Fougerat , Maxime Guillaume
55. Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD), Sep 2019, Barcelona, Spain. 1 p
Conference papers hal-02734566v1

Early life stress induces type 2 diabetes-like features in ageing mice

Hanna Ilchmann-Diounou , Maïwenn Olier , Corinne Lencina , Ambre Riba , Sharon Barretto
NeuroGASTRO 2019 Congress, Sep 2019, Lisbon, Portugal. 1 p
Conference papers hal-02736934v1
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Hepatocyte PI3Kα controls the PPARα-FGF21 axis and regulates whole body fatty acid homeostasis

Marion Régnier , Arnaud Polizzi , Céline Lukowicz , S. Smati , Anne Fougerat
European Assocation for the Study of Diabetes (EASD), Oct 2018, Berlin, Germany
Conference papers hal-04442612v1

Constitutive Androstane Receptor deficiency leads to sexually dimorphic metabolic disorders in aging

Céline Lukowicz , Marion Régnier , Frédéric Lasserre , Arnaud Polizzi , Alexandra Montagner
54. Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD), European Association for the Study of Diabetes (EASD). GBR., Oct 2018, Berlin, France. pp.1
Conference papers hal-02735254v1

Hepatokines in metabolic disease: novel insights into FGF21 regulation by glucose

Catherine Postic , Alison Iroz , Alexandra Montagner , Fadila Benhamed , Arnaud Polizzi
52. Annual Scientific Meeting of the European Society for Clinical Investigation “Precision medicine for healthy ageing”, May 2018, Barcelone, Spain. pp.1
Conference papers hal-02734271v1

Influence of gender on progression of liver metabolic diseases in response to different nutritional challenges

Sarra Smati , Arnaud Polizzi , Marion Régnier , Alain Marrot , Céline Lukowicz
54. Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD), European Association for the Study of Diabetes (EASD). GBR., Oct 2018, Berlin, Germany. pp.1
Conference papers hal-02735253v1
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Intracellular lipids: an independent cause of liver injury and chronic kidney disease in non-alcoholic fatty liver disease-like context

Laure Monteillet , Monika Gjorgjieva , Marine Silva , Vincent Verzieux , Hervé Guillou
G2L2, Oct 2018, Genève, Switzerland
Conference papers inserm-02388687v1
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Early life stress induces type 2 diabetes at adulthood in male mice

Hanna Ilchmann-Diounou , Maïwenn Olier , Corinne Lencina , Sandrine Ellero-Simatos , Ambre Riba
10. International Meeting of Pediatric Endocrinology, Sep 2017, Washington, United States
Conference papers hal-01603069v1
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Hepatocyte PI3Kα controls the PPARα-FGF21 axis and regulates whole body fatty acid homeostasis

Marion Régnier , Arnaud Polizzi , Céline Lukowicz , Edwin Fouché , Frédéric Lasserre
EMBO meeting, Apr 2017, Majorqua, Spain
Conference papers hal-04442626v1
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Chronic maternal separation in mice impaired immuno-metabolism in older offspring on standard diet

Hanna Ilchmann-Diounou , Corinne Lencina , Sandrine Ellero-Simatos , Ambre Riba , Cherryl Harkat
The Neonatal Window of Opportunity, Early Priming for Life, Herrenhausen Conference, Dec 2016, Hanovre, Germany
Conference papers hal-01608144v1

Specific modulation of hepatic estrogen receptor alpha prevents fatty liver but also obesity and insulin resistance induced by a high fat diet in mice

Maeva Guillaume , Sandra Handgraaf , Isabelle Raymond-Letron , Aude Fabre , Elodie Riant
50th International Liver Congress of the European-Association-for-the-Study-of-the-Liver, European Association for the Study of the Liver (EASL). Genève, CHE., Apr 2015, Vienne, Austria. 1 p
Conference papers hal-02743029v1

Partial inhibition of hormone-sensitive lipase improves insulin sensitivity by induction of de novo lipogenesis and elongase ELOVL6 in human adipocytes

Pauline Morigny , Marianne Houssier , Sylvie Caspar Bauguil , Diane Beuzelin , Aline Mairal
51. Annual Meeting of the European Association for the Study of Diabetes (EASD), European Association for the Study of Diabetes (EASD). Düsseldorf, GBR., Sep 2015, Stockholm, Sweden. 2 p
Conference papers hal-02744175v1

Contribution of the nuclear receptors PXR and CAR to gene expression modulations induced by fipronil in rodent liver

Béatrice Roques , Marlène Z. Lacroix , Nabila Moussaoui , Julien Leghait , Sylvie Puel
4th Health Food Symposium, Pôle Aliment Sécurité Sanitaire & Santé (PA3S)., 2012, Toulouse, France
Conference papers hal-02802231v1
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Contribution of the nuclear receptors PXR and CAR to gene expression modulations induced by fipronil in rodent liver

Béatrice Roques , Marlène Z. Lacroix , Nabila Moussaoui , Julien Leghait , Sylvie Puel
12th International Congress of the European Association for Veterinary Pharmacology and Toxicology (EAVPT), Jul 2012, Noordwijkerhout, Netherlands. pp.1-182
Conference papers hal-02744689v1

An xosysterol sensor and a master regulator of lipogenesis

Hervé Guillou
ENOR meeting, Saisissez le nom du laboratoire, du service ou du département., Ville service., Sep 2011, Rome, Italy
Conference papers hal-02802433v1

Regulation of hepatic lipid metabolism: effect of dietary fatty acids and effect of Bisphenol A.

Hervé Guillou
ENS Lyon, Ecole Normale Supérieure (ENS). Dr Hugo Aguilaniu, Lyon, FRA., Apr 2011, Lyon, France
Conference papers hal-02803044v1

Oxysterol signaling in fatty acid metabolism

Hervé Guillou
INSERM U915, L'institut du Thorax, Saisissez le nom du laboratoire, du service ou du département., Ville service., Jan 2011, Nantes, France
Conference papers hal-02802818v1

Régulation du Liver X Receptor par le fructose et développement de la stéatose hépatique

Simon Ducheix , F Rayah-Benhamed , Alexandra Montagner , Arnaud Polizzi , Frédéric Lasserre
9. Journées Francophones de Nutrition (JFN), Ville service., Dec 2011, Reims, France
Conference papers hal-02805683v1
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Integrating QTL controlling fatness, lipid metabolites and gene expressions to genetically dissect the adiposity complex trait in a meat chicken cross

Yuna Blum , Olivier O. Demeure , Colette Désert , Hervé Guillou , J Bertrand-Michel
62. Annual Meeting of the European Association for Animal Production (EAAP), Aug 2011, Stavanger, Norway
Conference papers hal-02748764v1

Rôle de LXR dans le métabolisme des acides gras

Hervé Guillou
Institut Cochin, Institut Cochin. Dr Catherine Postic, Ville service, FRA., Mar 2011, Cochin, France
Conference papers hal-02802820v1

L’expression d’une forme active de ChREBP conduit à la réinduction de la lipogenèse dans un modèle animal de déficience en LXR et SREBP-1c

A. Poupeau , F. Rayah-Benhamed , R. Dentin , Hervé Guillou , .J. Girard
69èmes journées de l'Agence Française d’Etude du Foie, Saisissez le nom du laboratoire, du service ou du département., Ville service., Sep 2011, Paris, France
Conference papers hal-02804525v1

ELOVL2 controls the level of n-628:5 and 30:5 fatty acids in testis, a prerequisite for male fertility and sperm maturation in mice

Damir Zadravec , Petr Tvrdik , Hervé Guillou , Richard Haslam , Tsutomu Kobayashi
52. International Conference on the Bioscience of Lipids : Expanding the Horizons of Lipidomics, International Conference on the Bioscience of Lipids (ICBL). INT., Aug 2011, Varsovie, Poland. ⟨10.1016/j.chemphyslip.2011.05.035⟩
Conference papers hal-02747851v1

Regulation of hepatic lipid metabolism: effect of dietary fatty acids and effect of Bisphenol A

Hervé Guillou
Centre de Génomique Integrative de Lausanne, Centre de Génomique Integrative de Lausanne., Feb 2011, Lausanne, Switzerland
Conference papers hal-02802819v1

Role of LXR in hepatic fatty acid homeostasis revealed through a nutrigenomic approach

Hervé Guillou
Journées des récepteurs nucléaires, Muséum National d’Histoire Naturelle (MNHN). Saisissez le nom du laboratoire, du service ou du département., Paris, FRA., Mar 2011, Paris, France
Conference papers hal-02802823v1

Power Allocation Problem in Charging Electric Vehicles with Photovoltaic Production

Hervé Guillou , Van-Dat Cung , Duy Long Ha , Mireille Jacomino
The 8th International Conference on Supply Chain Management and Information Systems (SCMIS2010), Oct 2010, Hong Kong, China. pp.720-725
Conference papers hal-00528686v1

Nuclear receptors in the transcriptional control of hepatic fatty acid metabolism

Hervé Guillou
The Wenner-Gren Institute, University of Stockholm, Sep 2009, Stockholm, Sweden. pp.Inconnu
Conference papers hal-02813403v1
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A minimal and dynamic model for fatty acid metabolism in mouse liver

Pierre Blavy , Florence Gondret , Hervé Guillou , Sandrine Lagarrigue , Pascal G.P. Martin
Journées Ouvertes de Biologie, Informatique et Mathématique (JOBIM), Jun 2008, Lille (FR), France
Conference papers hal-00729742v1

A minimal and dynamic model for fatty acid metabolism in mouse liver

Pierre Blavy , Florence Gondret , Hervé Guillou , Sandrine Lagarrigue , Pascal G.P. Martin
Journées Ouvertes de Biologie, Informatique et Mathématique (JOBIM), Jun 2008, Lille, France
Conference papers hal-02756716v1

A minimal and dynamical model for fatty acid metabolism in mouse liver

Pierre Blavy , Florence Gondret , Hervé Guillou , Sandrine Lagarrigue , Pascal G.P. Martin
Journées Ouvertes Biologie Informatique Mathématiques, 2008, Lille, France. pp.Inconnu
Conference papers hal-02817340v1

Empreintes transcriptionnelles de lipides alimentaires sur modèles souris

Pascal G.P. Martin , Hervé Guillou , Frédéric Lasserre , S Dejean , P Legrand
Analyse intégrée de signatures variées GENOTOUL, 2005, Toulouse, France. pp.Inconnu
Conference papers hal-02825872v1

PPARa remplit-il véritablement la fonction de senseur nutritionnel vis-à-vis des acides gras alimentaires ? Une étude comparée de signatures transcriptomique et lipidomique

Pascal G.P. Martin , Frédéric Lasserre , Hervé Guillou , R Barnouin , S Dejean
Journée GERLI de lipidomique, 2005, Toulouse, France. pp.Inconnu
Conference papers hal-02829883v1

Influence des acides gras alimentaires sur les voies de signalisation des récepteurs nucléaires : une étude comparée de signatures transcriptomique et lipidomique

Pascal G.P. Martin , Frédéric Lasserre , Hervé Guillou , R Barnouin , S Dejean
Journées Scientifiques du GIS « PA-3S », 2005, Boussens, France. pp.Inconnu
Conference papers hal-02834051v1

A kinetic view of coordinate modulations of gene expression and metabolism in wild-type and PPARa-/- mice during fasting

Pgp Martin , R Barnouin , Frédéric Lasserre , Hervé Guillou , Michela Cantiello
Cycles de conferences de l'IFR31, 2005, Toulouse, France. pp.Inconnu
Conference papers hal-02832532v1

A kinetic view of coordinate modulations of gene expression and metabolism in wild-type and PPARa-/- mice during fasting

R Barnouin , Frédéric Lasserre , Michela Cantiello , Hervé Guillou , Thierry Pineau
Gene signature symposia, 2005, Paris, France. pp.Inconnu
Conference papers hal-02828236v1

Caractérisation des effets hépatiques induits par les lipides alimentaires par analyse de leurs signatures biologiques chez la souris

Pascal G.P. Martin , Hervé Guillou , Frédéric Lasserre , S Dejean , P Legrand
Journée d’animation scientifique de l’IFR30, 2004, Toulouse, France. pp.Inconnu
Conference papers hal-02825956v1

Expression and activity of two recombinant isoforms of rat NMT1

Vincent V. Rioux , Frédérique F. Pédrono , Stéphanie Daval , Daniel D. Catheline , Monique Bouriel
6th Congress of International Society for the Study of Fatty Acids and Lipids (ISSFAL), Jun 2004, Brighton, United Kingdom
Conference papers hal-03348632v1

Characterization of hepatic effects induced by food lipids from the analysis of their biological signatures in mice

Pascal G.P. Martin , Hervé Guillou , Frédéric Lasserre , A Paris , S Dejean
Journée d’animation du Département d’Alimentation Humaine de l’INRA, 2004, Paris, France. pp.Inconnu
Conference papers hal-02826237v1

Is PPARa a true nutritional sensor for dietary fatty acids: a coordinate transcriptomic and lipidomic study

Pascal G.P. Martin , Frédéric Lasserre , Hervé Guillou , R Barnouin , S Dejean
Journée d’animation scientifique de l’IFR31, 2004, Toulouse, France. pp.Inconnu
Conference papers hal-02829897v1

Biological effects of nutrients : what interdisciplinary strategies to grasp and analyze complex signatures

Pascal G.P. Martin , Frédéric Lasserre , Hervé Guillou , R Barnouin , S Dejean
Journée d’animation du Département d’Alimentation Humaine de l’INRA, 2004, Paris, France. pp.Inconnu
Conference papers hal-02833182v1

A kinetic view of coordinate modulations of gene expression and metabolism in wild type and PPARa-/- mice during fasting

R Barnouin , Frédéric Lasserre , M Cantielo , Hervé Guillou , Thierry Pineau
Conference of the Paul Hamel Institute / New developements in the metabolic syndrome, 2004, Monaco, France. pp.Inconnu
Conference papers hal-02828078v1

Activité de la myristoyl-CoA: protéine N-myristoyltransférase de rat exprimée dans les cellules COS-7.

Vincent V. Rioux , M. Ravache , Etienne Cognard , Stéphanie Daval , Hervé Guillou
Groupe d’Etude et de Recherche sur les Lipides et les Lipoprotéines (GERLI), Diversité moléculaire et physiopathologie, Sep 2003, Paris, France
Conference papers hal-03348639v1

Effects of dietary fatty acids on the expression of an array of class II nuclear receptor target genes

Pascal G.P. Martin , Hervé Guillou , Frédéric Lasserre , Cécile Calléja , Sophie Jan
Inconnu, 2003, pp.Inconnu
Conference papers hal-02833157v1

Regulation of hepatic desaturases by PPAR alpha

Hervé Guillou , Pascal G.P. Martin , Sophie Jan , Sabine d'Andrea , Alain Roulet
Inconnu, 2003, pp.Inconnu
Conference papers hal-02832865v1

Effet des acides gras saturés sur l’activité et l’expression des D6- et D5-désaturases

Sophie Jan , Hervé Guillou , Sabine d'Andrea , Stéphanie Daval , Emmanuelle Dumont
4èmes Journées Francophones de Nutrition, Nov 2002, Dijon, France
Conference papers hal-03348641v1

Modelisation de la digestion gastrique des proteines du lait

Benedicte Savalle , P. Garnier , Guy Miranda , Hervé Guillou , J.P. Pelissier
Journee d'automne d'information scientifique, Oct 1987, Jouy-en-Josas, France
Conference papers hal-02783241v1

Transcriptional regulation of hepatic fatty acid metabolism

Hervé Guillou , Pgp Martin , Thierry Pineau
Subcellular Biochemistry: Lipids in Health and Disease, Springer, 2009
Book sections hal-02815951v1