HG

Hervé Guillou

CV Hervé Guillou Directeur de Recherche INRAE
169
Documents
Identifiants chercheurs

Présentation

Hervé Guillou (INRAE Toulouse)

Born in Brest 13/09/1975

herve.guillou@inrae.fr

https://orcid.org/0000-0002-5363-9081

Since 2018: Member of unit board of directors (UMR1331 INRAE Toulouse)

Since 2016: Senior investigator (DR) INRAE Toulouse, ToxAlim

Since 2009: Group leader, “Integrative Toxicology and Metabolism”, INRAE ToxAlim

2008: Junior investigator (CR) INRAE Toulouse, Molecular Pharmacology (Dir: Dr T. Pineau)

2004 –2007: Post-doctoral scientist at Babraham Institute (Cambridge UK)

Cell Signaling department (led by Dr L.R. Stephens et Dr P.T. Hawkins)

2000- 2004: Assistant lecturer in biochemistry, Agrocampus Rennes

Degrees

2014: HDR – Toulouse University (France)

2004: PhD in biochemistry and Cell Biology (Rennes University, France)

2000: MSc in Physiology (Rennes University, France)

Teaching and training

Teaching: Pre-clinical Toxicology, Molecular endocrinology, Metabolism, Physiology and Hepatology, Lipid Biochemistry (MSc, University of Toulouse)

PhD Supervised (and current position): Dr Simon Ducheix (PhD 2014; PI INSERM Nantes), Dr Alexia Buis (PhD 2018; started her own company), Dr Marion Régnier (PhD 2018; Post-doc, Institut Cochin), Dr Sarra Smati (MD, PhD 2019; Assistant Professor, University of Nantes), Dr Tiffany Fougeray (PhD 2020; Post-doc, Harvard Medical School), Dr Léonie Dopavogui (PhD 2021; Industry, Canada).

Post-doctoral scientist (and current position): Dr Normand Podechard (2009-2011; Professor Rennes University of Pharmacy), Dr Alexandra Montagner (2011-2016; Principal Investigator INSERM Toulouse), Dr Anne Fougerat (2017-2021; Principal Investigator INRAE Toulouse), Dr Elena Piccinin (2022; Assistant Professor, University of Bari).

Fundings & Awards

Young scientist award from the French Society of Nutrition in 2014

Awards from the Francophone Society of Diabetes in 2015 and 2019

Fundings: ANR, ARC, INCA, SFD, SFN, AFEF, Occitanie, ANSES, FRM, EU (JPI)

Publications & Communication

80 talks including selected oral communications at international meetings (Keystone Symposium; EMBO Meeting, EASD, EASL)

110 peer reviewed publications in international journals

Full publication list available at https://scholar.google.fr/citations?user=Toi0KcYAAAAJ&hl=fr

Publications

Publications

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Association between dietary pesticide exposure profiles and body weight change in French adults: Results from the NutriNet-Santé cohort

Justine Berlivet , Laurence Payrastre , Pauline Rebouillat , Anne Fougerat , Mathilde Touvier et al.
Environment International, 2024, 184, pp.108485. ⟨10.1016/j.envint.2024.108485⟩
Article dans une revue hal-04725361 v1
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Pivotal role of intestinal cholesterol and nuclear receptor LXR in metabolic liver steatohepatitis and hepatocarcinoma

Elena Piccinin , Maria Arconzo , Emanuela Pasculli , Angela Fulvia Tricase , Silvia Cultrera et al.
Cell & Bioscience, 2024, 14, ⟨10.1186/s13578-024-01248-y⟩
Article dans une revue hal-04671281 v1

Physiopathologie de la stéatose hépatique non-alcoolique (NAFLD)

Lucia Parlati , Marion Régnier , Catherine Postic , Hervé Guillou
Médecine des Maladies Métaboliques, 2023, in press, ⟨10.1016/j.mmm.2023.03.005⟩
Article dans une revue hal-04066670 v1

C/EBPα Confers Dependence to Fatty Acid Anabolic Pathways and Vulnerability to Lipid Oxidative Stress–Induced Ferroptosis in FLT3 -Mutant Leukemia

Marie Sabatier , Rudy Birsen , Laura Lauture , Sarah Mouche , Paolo Angelino et al.
Cancer Discovery, 2023, 13 (7), pp.1720-1747. ⟨10.1158/2159-8290.CD-22-0411⟩
Article dans une revue hal-04166110 v1

Monoacylglycerol lipase reprograms hepatocytes and macrophages to promote liver regeneration

Manon Allaire , Rola Al-Sayegh , Morgane Mabire , Adel Hammoutene , Matthieu Siebert et al.
JHEP Reports Innovation in Hepatology, 2023, 5 (8), pp.100794. ⟨10.1016/j.jhepr.2023.100794⟩
Article dans une revue hal-04178833 v1
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The interplay between dietary fatty acids and gut microbiota influences host metabolism and hepatic steatosis

Marc Schoeler , Sandrine Ellero-Simatos , Till Birkner , Jordi Mayneris-Perxachs , Lisa Olsson et al.
Nature Communications, 2023, 14 (1), pp.5329. ⟨10.1038/s41467-023-41074-3⟩
Article dans une revue hal-04197137 v1

Obesity promotes fumonisin B1 hepatotoxicity

Léonie Dopavogui , Marion Régnier , Arnaud Polizzi , Quentin Ponchon , Sarra Smati et al.
Science of the Total Environment, 2023, 891, pp.164436. ⟨10.1016/j.scitotenv.2023.164436⟩
Article dans une revue hal-04112262 v1

Evidence for constitutive microbiota-dependent short-term control of food intake in mice: Is there a link with inflammation, oxidative stress, endotoxemia, and Glp-1?

Selma Ben Fradj , Emmanuelle Nédélec , Juliette Salvi , Mélanie Fouesnard , Marine Huillet et al.
Antioxidants and Redox Signaling, 2022, 37 (4-6), pp.349-369. ⟨10.1089/ars.2021.0095⟩
Article dans une revue hal-03594297 v1
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Tissular Genomic Responses to Oral FB1 Exposure in Pigs

Léonie Dopavogui , Arnaud Polizzi , Anne Fougerat , Pascal Gourbeyre , Chloé Terciolo et al.
Toxins, 2022, 14 (2), pp.83. ⟨10.3390/toxins14020083⟩
Article dans une revue hal-03609600 v1
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Zac1 and the Imprinted Gene Network program juvenile NAFLD in response to maternal metabolic syndrome

Marine Baptissart , Christine Bradish , Brie Jones , Evan Walsh , Jesse Tehrani et al.
Hepatology, 2022, in press, ⟨10.1002/hep.32363⟩
Article dans une revue hal-03602068 v1
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NMR-based metabolic profiling and discrimination of wild tropical tunas by species, size category, geographic origin, and on-board storage condition

Nathalie Bodin , Aurélien Amiel , Edwin Fouché , Fany Sardenne , Emmanuel Chassot et al.
Food Chemistry, 2022, 371, ⟨10.1016/j.foodchem.2021.131094⟩
Article dans une revue hal-03376705 v1
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The hepatocyte insulin receptor is required to program the liver clock and rhythmic gene expression

Tiffany Fougeray , Arnaud Polizzi , Marion Régnier , Anne Fougerat , Sandrine Ellero-Simatos et al.
Cell Reports, 2022, 39 (2), pp.110674. ⟨10.1016/j.celrep.2022.110674⟩
Article dans une revue hal-03647009 v1
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Prospective association between dietary pesticide exposure profiles and type 2 diabetes risk in the NutriNet-Santé cohort

Pauline Rebouillat , Rodolphe Vidal , Jean-Pierre Cravedi , Bruno Taupier-Letage , Laurent Debrauwer et al.
Environmental Health, 2022, 21 (1), pp.57. ⟨10.1186/s12940-022-00862-y⟩
Article dans une revue hal-03689933 v1

Monoacylglycerol lipase inhibition specifically in macrophages compromises liver regeneration by inducing interferon type 1 that negatively impacts on hepatocyte proliferation

Manon Allaire , Rola Al-Sayegh , Morgane Mabire , Matthieu Siebert , Mathilde Cadoux et al.
Journal of Hepatology, 2022, 77, pp.S65
Article dans une revue hal-03765301 v1
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ATGL-dependent white adipose tissue lipolysis controls hepatocyte PPARα activity

Anne Fougerat , Gabriele Schoiswohl , Arnaud Polizzi , Marion Régnier , Carina Wagner et al.
Cell Reports, 2022, 39 (10), ⟨10.1016/j.celrep.2022.110910⟩
Article dans une revue hal-03695833 v1
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Integrative study of diet-induced mouse models of NAFLD identifies PPARα as a sexually dimorphic drug target

Sarra Smati , Arnaud Polizzi , Anne Fougerat , Sandrine Ellero-Simatos , Yuna Blum et al.
Gut, 2022, 71 (4), pp.807-821. ⟨10.1136/gutjnl-2020-323323⟩
Article dans une revue hal-03215969 v1
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Reduction in gut‐derived MUFAs via intestinal stearoyl‐CoA desaturase 1 deletion drives susceptibility to NAFLD and hepatocarcinoma

Simon Ducheix , Elena Piccinin , Claudia Peres , Oihane Garcia-Irigoyen , Justine Bertrand-Michel et al.
Hepatology Communications, 2022, ⟨10.1002/hep4.2053⟩
Article dans une revue hal-03758408 v1
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Endoplasmic reticulum stress controls iron metabolism through TMPRSS6 repression and hepcidin mRNA stabilization by RNA-binding protein HuR

Audrey Belot , Ophélie Gourbeyre , Anais Palin , Aude Rubio , Amélie Largounez et al.
Haematologica, 2021, 106 (4), pp.1202-1206. ⟨10.3324/haematol.2019.237321⟩
Article dans une revue hal-02911817 v1
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New targets for NAFLD

Lucia Parlati , Marion Régnier , Hervé Guillou , Catherine Postic
JHEP Reports Innovation in Hepatology, 2021, 3 (6), pp.100346. ⟨10.1016/j.jhepr.2021.100346⟩
Article dans une revue hal-03472343 v1
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The pregnane X receptor drives sexually dimorphic hepatic changes in lipid and xenobiotic metabolism in response to gut microbiota in mice

Sharon Barretto , Frédéric Lasserre , Marine Huillet , Marion Régnier , Arnaud Polizzi et al.
Article dans une revue hal-03209709 v1
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Dual regulation of TxNIP by ChREBP and FoxO1 in liver

Bénédicte Noblet , Fadila Benhamed , Insug O-Sullivan , Wenwei Zhang , Gaelle Filhoulaud et al.
iScience, 2021, 24 (3), pp.102218. ⟨10.1016/j.isci.2021.102218⟩
Article dans une revue hal-03176271 v1
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Hepatocyte-specific deletion of Pparα promotes NAFLD in the context of obesity

Marion Régnier , Arnaud Polizzi , Sarra Smati , Céline Lukowicz , Anne Fougerat et al.
Scientific Reports, 2020, 10 (1), pp.6489. ⟨10.1038/s41598-020-63579-3⟩
Article dans une revue inserm-02875414 v1
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Regulation of hepatokine gene expression in response to fasting and feeding: Influence of PPARa and insulin-dependent signaling in hepatocytes

Sarra Smati , Marion Régnier , Tiffany Fougeray , Arnaud Polizzi , Anne Fougerat et al.
Diabetes & Metabolism, 2020, 46 (2), pp.129-136. ⟨10.1016/j.diabet.2019.05.005⟩
Article dans une revue hal-02402566 v1
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Proton NMR enables the absolute quantification of aqueous metabolites and lipid classes in unique mouse liver samples

Aurélien Amiel , Marie Tremblay-Franco , Roselyne Gautier , Simon Ducheix , Alexandra Montagner et al.
Metabolites, 2020, 10 (1), 20 p. ⟨10.3390/metabo10010009⟩
Article dans une revue hal-02622894 v1
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Important Considerations for Sample Collection in Metabolomics Studies with a Special Focus on Applications to Liver Functions

Lorraine Smith , Joran Villaret-Cazadamont , Sandrine P Claus , Cécile Canlet , Hervé Guillou et al.
Metabolites, 2020, 10 (3), pp.104. ⟨10.3390/metabo10030104⟩
Article dans une revue hal-02556806 v1
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Perinatal exposure to a dietary pesticide cocktail does not increase susceptibility to high-fat diet-induced metabolic perturbations at adulthood but modifies urinary and fecal metabolic fingerprints in C57Bl6/J mice

Lorraine Smith , Wendy Klement , Léonie Dopavogui , Frédéric de Bock , Frédéric Lasserre et al.
Environment International, 2020, 144, pp.106010. ⟨10.1016/j.envint.2020.106010⟩
Article dans une revue hal-02912899 v1
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Oxidative Stress in NAFLD: Role of Nutrients and Food Contaminants

Clémence Rives , Anne Fougerat , Sandrine Ellero-Simatos , Nicolas Loiseau , Hervé Guillou et al.
Biomolecules, 2020, 10 (12), pp.1702. ⟨10.3390/biom10121702⟩
Article dans une revue hal-03100801 v1
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Peroxisome Proliferator-Activated Receptors and Their Novel Ligands as Candidates for the Treatment of Non-Alcoholic Fatty Liver Disease

Anne Fougerat , Alexandra Montagner , Nicolas Loiseau , Hervé Guillou , Walter Wahli
Cells, 2020, 9 (7), pp.1638. ⟨10.3390/cells9071638⟩
Article dans une revue hal-02899682 v1
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Author correction: Dimorphic metabolic and endocrine disorders in mice lacking the constitutive androstane receptor

Céline Lukowicz , Sandrine Ellero-Simatos , Marion Régnier , Fabiana Oliviero , Frédéric Lasserre et al.
Scientific Reports, 2020, 10 (1), ⟨10.1038/s41598-020-61226-5⟩
Article dans une revue hal-02627769 v1
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Peroxisome Proliferator-Activated Receptors and Caloric Restriction-Common Pathways Affecting Metabolism, Health, and Longevity

Kalina Duszka , András Gregor , Hervé Guillou , Jürgen König , Walter Wahli
Article dans une revue hal-02904081 v1
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Depletion of gram-positive bacteria impacts hepatic biological functions during the light phase

Hui Yun Penny Oh , Sandrine Ellero-Simatos , Ravikumar Manickam , Nguan Soon Tan , Hervé Guillou et al.
International Journal of Molecular Sciences, 2019, 20 (4), 28 p. ⟨10.3390/ijms20040812⟩
Article dans une revue hal-02620345 v1
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Gene expression profiling reveals that PXR activation inhibits Hhepatic PPAR alpha activity and decreases FGF21 secretion in male C57Bl6/J mice

Sharon Barretto , Frédéric Lasserre , Anne Fougerat , Lorraine Smith , Tiffany Fougeray et al.
International Journal of Molecular Sciences, 2019, 20 (15), ⟨10.3390/ijms20153767⟩
Article dans une revue hal-02617929 v1
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Interaction between Hormone-Sensitive Lipase and ChREBP in Fat Cells Controls Insulin Sensitivity

Pauline Morigny , Marianne Houssier , Aline Mairal , Claire Ghilain , Etienne Mouisel et al.
Nature Metabolism, 2019, 1 (1), pp.133-146. ⟨10.1038/s42255-018-0007-6⟩
Article dans une revue inserm-02150261 v1
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The protective role of liver X receptor (LXR) during fumonisin B1-induced hepatotoxicity

Marion Régnier , Arnaud Polizzi , Céline Lukowicz , Sarra Smati , Frédéric Lasserre et al.
Archives of Toxicology, 2019, 93 (2), pp.505-517. ⟨10.1007/s00204-018-2345-2⟩
Article dans une revue hal-02619117 v1
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Early life stress induces type 2 diabetes-like features in ageing mice

Hanna Ilchmann-Diounou , Maïwenn Olier , Corinne Lencina , Ambre Riba , Sharon Barretto et al.
Brain, Behavior, and Immunity, 2019, 80, pp.452-463. ⟨10.1016/j.bbi.2019.04.025⟩
Article dans une revue hal-02627238 v1

Inhibition of monoacylglycerol lipase, an anti-inflammatory and antifibrogenic strategy in the liver

Aida Habib , Dina Chokr , Jinghong Wan , Pushpa Hegde , Morgane Mabire et al.
Gut, 2019, 68 (3), pp.522-532. ⟨10.1136/gutjnl-2018-316137⟩
Article dans une revue hal-02963612 v1
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Dimorphic metabolic and endocrine disorders in mice lacking the constitutive androstane receptor

Céline Lukowicz , Sandrine Ellero-Simatos , Marion Régnier , Fabiana Oliviero , Frédéric Lasserre et al.
Scientific Reports, 2019, 9 (1), pp.20169. ⟨10.1038/s41598-019-56570-0⟩
Article dans une revue hal-02428712 v1
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The class 3 PI3K coordinates autophagy and mitochondrial lipid catabolism by controlling nuclear receptor PPARα

Anton Iershov , Ivan Nemazanyy , Chantal Alkhoury , Muriel Girard , Esther Barth et al.
Nature Communications, 2019, 10 (1), 18 p. ⟨10.1038/s41467-019-09598-9⟩
Article dans une revue hal-02622186 v1

Sphingolipid metabolism in non-alcoholic fatty liver diseases

Marion Régnier , Arnaud Polizzi , Hervé Guillou , Nicolas Loiseau
Biochimie, 2019, 159, pp.9-22. ⟨10.1016/j.biochi.2018.07.021⟩
Article dans une revue hal-02626541 v1
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PGC-1 alpha induced browning promotes involution and inhibits lactation in mammary glands

Elena Piccinin , Annalisa Morgano , Claudia Peres , Annalisa Contursi , Justine Bertrand-Michel et al.
Cellular and Molecular Life Sciences, 2019, 76 (24), pp.5011-5025. ⟨10.1007/s00018-019-03160-y⟩
Article dans une revue hal-02622923 v1
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Coelomocytes regulate starvation-induced fat catabolism and lifespan extension through the lipase LIPL-5 in Caenorhabditis elegans

Alexia Buis , Stéphanie Bellemin , Jérôme Goudeau , Léa Monnier , Nicolas Loiseau et al.
Cell Reports, 2019, 28 (4), 1041-1049 + 6 p. ⟨10.1016/j.celrep.2019.06.064⟩
Article dans une revue hal-02628480 v1

β-catenin oncogenic activation rewires fatty acid catabolism to fuel hepatocellular carcinoma

Alexandra Montagner , Laurent Le Cam , Hervé Guillou
Gut, 2019, 68 (2), pp.183-185. ⟨10.1136/gutjnl-2018-316557⟩
Article dans une revue hal-02448229 v1
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Selective Liver Estrogen Receptor Modulation Prevents Steatosis, Diabetes, and Obesity Through the Anorectic Growth Differentiation Factor 15 Hepatokine in Mice

Maeva Guillaume , Elodie Riant , Aurélie Fabre , Isabelle Raymond‐letron , Melissa Buscato et al.
Hepatology Communications, 2019, 3 (7), pp.908-924. ⟨10.1002/hep4.1363⟩
Article dans une revue hal-02277993 v1
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Hepatic PPARalpha is critical in the metabolic adaptation to sepsis

Réjane Paumelle , Joël Haas , Nathalie Hennuyer , Eric Baugé , Yann Deleye et al.
Journal of Hepatology, 2019, 70 (5), pp.963-973. ⟨10.1016/j.jhep.2018.12.037⟩
Article dans une revue inserm-02109735 v1
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Metabolic effects of a chronic dietary exposure to a low-dose oesticide cocktail in mice: Sexual dimorphism and role of the constitutive androstane receptor

Céline Lukowicz , Sandrine Ellero-Simatos , Marion Régnier , Arnaud Polizzi , Frédéric Lasserre et al.
Environmental Health Perspectives, 2018, 126 (6), 18 p. ⟨10.1289/EHP2877⟩
Article dans une revue hal-02624889 v1
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Complementary intestinal mucosa and microbiota responses to caloric restriction

Kalina Duszka , Sandrine Ellero-Simatos , Ghim Siong Ow , Marianne Defernez , Eeswari Paramalingam et al.
Scientific Reports, 2018, 8, ⟨10.1038/s41598-018-29815-7⟩
Article dans une revue hal-02621482 v1
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The histone demethylase Phf2 acts as a molecular checkpoint to prevent NAFLD progression during obesity

Julien Bricambert , Marie-Clotilde Alves-Guerra , Pauline Esteves , Carina Prip-Buus , Justine Bertrand-Michel et al.
Nature Communications, 2018, 9 (1), ⟨10.1038/s41467-018-04361-y⟩
Article dans une revue hal-02122655 v1
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Dual extraction of mRNA and lipids from a single biological sample

Normand Podechard , Simon Ducheix , Arnaud Polizzi , Frédéric Lasserre , Alexandra Montagner et al.
Scientific Reports, 2018, 8 (1), pp.7019. ⟨10.1038/s41598-018-25332-9⟩
Article dans une revue hal-01794296 v1
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Intracellular lipids are an independent cause of liver injury and chronic kidney disease in non alcoholic fatty liver disease-like context

Laure Monteillet , Monika Gjorgjieva , Marine Silva , Vincent Verzieux , Linda Imikirene et al.
Molecular metabolism, 2018, 16, pp.100-115. ⟨10.1016/j.molmet.2018.07.006⟩
Article dans une revue inserm-02339561 v1

40 Ar/ 39 Ar age of cryptochron C2r.2r-1 as recorded in a lava sequence within the Ko'olau volcano (Hawaii, USA)

Hervé Guillou , Vincent Scao , Sébastien Nomade
Quaternary Geochronology, 2018, 43, pp.91 - 101. ⟨10.1016/j.quageo.2017.10.005⟩
Article dans une revue hal-01806763 v1

Selective activation of estrogen receptor alpha activation function-1 is sufficient to prevent obesity, steatosis, and insulin resistance in mouse

Maeva Guillaume , Sandra Handgraaf , Aurelie J Fabre , Isabelle Raymond-Letron , Elodie Riant et al.
American Journal of Pathology, 2017, 187 (6), pp.1273-1287. ⟨10.1016/j.ajpath.2017.02.013⟩
Article dans une revue hal-01603827 v1
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Glycerol-3-phosphate acyltransferase 2 expression modulates cell roughness and membrane permeability: An atomic force microscopy study

Elizabeth R. Cattaneo , Eduardo Prieto , Maria B. Garcia-Fabiani , Mauro A. Montanaro , Hervé Guillou et al.
PLoS ONE, 2017, 12 (12), 18 p. ⟨10.1371/journal.pone.0189031⟩
Article dans une revue hal-02622165 v1
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Dietary oleic acid regulates hepatic lipogenesis through a liver X receptor-dependent signaling

Simon Ducheix , Alexandra Montagner , Arnaud Polizzi , Frédéric Lasserre , Marion Régnier et al.
PLoS ONE, 2017, 12 (7), ⟨10.1371/journal.pone.0181393⟩
Article dans une revue hal-01606929 v1
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Identification of signaling pathways targeted by the food contaminant FB1: Transcriptome and kinome analysis of samples from pig liver and intestine

Marion Régnier , Pascal Gourbeyre , Philippe Pinton , Scott Napper , Joëlle Laffitte et al.
Molecular Nutrition and Food Research, 2017, in press (12), 42 p. ⟨10.1002/mnfr.201700433⟩
Article dans une revue hal-01606651 v1
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A Specific ChREBP and PPARα Cross-Talk Is Required for the Glucose-Mediated FGF21 Response

Alison Iroz , Alexandra Montagner , Fadila Benhamed , Françoise Levavasseur , Arnaud Polizzi et al.
Cell Reports, 2017, 21 (2), pp.403 - 416. ⟨10.1016/j.celrep.2017.09.065⟩
Article dans une revue hal-01837159 v1

Insights into the role of hepatocyte PPARα activity in response to fasting

Marion Régnier , Arnaud Polizzi , Yannick Lippi , Edwin Fouché , Géraldine Michel et al.
Molecular and Cellular Endocrinology, 2017, in press, ⟨10.1016/j.mce.2017.07.035⟩
Article dans une revue hal-01605514 v1

Type 2 diabetes prevention through hormone sensitive lipase inhibition: elongase ELOVL6 at the center of attention

P. Morigny , M. Houssier , E. Mouisel , A. Mairal , S. Caspar-Bauguil et al.
Diabetologia, 2017, 60, pp.S249
Article dans une revue hal-02624062 v1

The suppression of hepatic glucose production improves metabolism and insulin sensitivity in subcutaneous adipose tissue in mice

Sylvie Casteras , Aya Abdul-Wahed , Maud Soty , Fanny Vulin , Hervé Guillou et al.
Diabetologia, 2016, 59 (12), pp.2645-2653. ⟨10.1007/s00125-016-4097-y⟩
Article dans une revue hal-01606287 v1
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White-to-brite conversion in human adipocytes promotes metabolic reprogramming towards fatty acid anabolic and catabolic pathways

V Barquissau , D. Beuzelin , D. Pisani , G.E. Beranger , A. Mairal et al.
Molecular metabolism, 2016, 5 (5), pp.352-365. ⟨10.1016/j.molmet.2016.03.002⟩
Article dans une revue hal-02134884 v1
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Hepatic fasting-induced PPAR alpha activity does not depend on essential fatty acids

Arnaud Polizzi , Edwin Fouché , Simon Ducheix , Frédéric Lasserre , Alice Marmugi et al.
International Journal of Molecular Sciences, 2016, 17 (10), pp.1624. ⟨10.3390/ijms17101624⟩
Article dans une revue hal-01476503 v1
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Perilipin 5 fine-tunes lipid oxidation to metabolic demand and protects against lipotoxicity in skeletal muscle

Claire Laurens , Virginie Bourlier , Aline Mairal , Katie Louche , Pierre-Marie Badin et al.
Scientific Reports, 2016, 6, ⟨10.1038/srep38310⟩
Article dans une revue hal-01605047 v1
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The gut microbiota: a major player in the toxicity of environmental pollutants?

Sandrine P. Claus , Hervé Guillou , Sandrine Ellero-Simatos
npj Biofilms and Microbiomes, 2016, 2, ⟨10.1038/npjbiofilms.2016.3⟩
Article dans une revue hal-01602371 v1

Novel Grb14-Mediated Cross Talk between Insulin and p62/Nrf2 Pathways Regulates Liver Lipogenesis and Selective Insulin Resistance

Lucie Popineau , Lucille Morzyglod , Nadege Carre , Michele Cauzac , Pascale Bossard et al.
Molecular and Cellular Biology, 2016, 36 (16), pp.2168 - 2181. ⟨10.1128/MCB.00170-16⟩
Article dans une revue hal-01602453 v1
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Intestinal PPAR gamma signalling is required for sympathetic nervous system activation in response to caloric restriction

Kalina Duszka , Alexandre Picard , Sandrine Ellero-Simatos , Jiapeng Chen , Marianne Defernez et al.
Scientific Reports, 2016, 6, ⟨10.1038/srep36937⟩
Article dans une revue hal-01606898 v1
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Glucocorticoid receptor-PPAR alpha axis in fetal mouse liver prepares neonates for milk lipid catabolism

Gianpaolo Rando , Chek Kun Tan , Nourhène Khaled , Alexandra Montagner , Nicolas Leuenberger et al.
eLife, 2016, 5, 31 p. ⟨10.7554/eLife.11853⟩
Article dans une revue hal-01602433 v1
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Effects of pesticide mixtures in human and animal models: an update of the recent literature

Virginie Rizzati , O. Briand , Hervé Guillou , Laurence Gamet-Payrastre
Chemico-Biological Interactions, 2016, 254, pp.231-246. ⟨10.1016/j.cbi.2016.06.003⟩
Article dans une revue (article de synthèse) hal-02637756 v1
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Transcriptional control of physiological and pathological processes by the nuclear receptor PPAR beta/delta

Nguan Soon Tan , Manuel Vázquez-Carrera , Alexandra Montagner , Ming Keat Sng , Hervé Guillou et al.
Progress in Lipid Research, 2016, 64, pp.98-122. ⟨10.1016/j.plipres.2016.09.001⟩
Article dans une revue hal-01594607 v1
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Hepatic circadian clock oscillators and nuclear receptors integrate microbiome-derived signals

Alexandra Montagner , Agata Korecka , Arnaud Polizzi , Yannick Lippi , Yuna Blum et al.
Scientific Reports, 2016, 6 (1), pp.1-14. ⟨10.1038/srep20127⟩
Article dans une revue hal-01482816 v1
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Localizing the lipid products of PI3Kγ in neutrophils

Laura Norton , Yvonne Lindsay , Arnaud Deladeriere , Tamara Chessa , Hervé Guillou et al.
Advances in Biological Regulation, 2016, 60, pp.36-45. ⟨10.1016/j.jbior.2015.10.005⟩
Article dans une revue hal-01602482 v1
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Activation of the Constitutive Androstane Receptor induces hepatic lipogenesis and regulates Pnpla3 gene expression in a LXR-independent way

Alice Marmugi , Céline Lukowicz , Frédéric Lasserre , Alexandra Montagner , Arnaud Polizzi et al.
Toxicology and Applied Pharmacology, 2016, 303, pp.90 - 100. ⟨10.1016/j.taap.2016.05.006⟩
Article dans une revue hal-01837194 v1
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Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD

Alexandra Montagner , Arnaud Polizzi , Edwin Fouché , Simon Ducheix , Yannick Lippi et al.
Gut, 2016, 65 (7), pp.1202-1214. ⟨10.1136/gutjnl-2015-310798⟩
Article dans une revue inserm-02339685 v1
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Combined QTL and selective sweep mappings with coding SNP annotation and cis-eQTL analysis revealed PARK2 and JAG2 as new candidate genes for adiposity regulation.

Pierre-François Roux , Simon Boitard , Anne Blum , Brian Parks , Alexandra Montagner et al.
G3, 2015, 5, pp.517-529. ⟨10.1534/g3.115.016865⟩
Article dans une revue hal-01194040 v1

Effect of obesity and metabolic syndrome on plasma oxysterols and fatty acids in human

Marie Tremblay-Franco , Chiara Zerbinati , Antonio Pacelli , Giuseppina Palmaccio , Carla Lubrano et al.
Steroids, 2015, 99 (Part B), pp.287-292. ⟨10.1016/j.steroids.2015.03.019⟩
Article dans une revue hal-02639945 v1
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New insights into the organ-specific adverse effects of fumonisin B1

Nicolas Loiseau , Arnaud Polizzi , Aude Dupuy , Nicole Therville , Mirindra Rakotonirainy et al.
Archives of Toxicology, 2015, 89 (9), pp.1619-1629. ⟨10.1007/s00204-014-1323-6⟩
Article dans une revue hal-03331305 v1
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Protective effects of n-6 fatty acids-enriched diet on intestinal ischaemia/reperfusion injury involve lipoxin A4 and its receptor

Thomas Gobbetti , Simon Ducheix , Pauline Le Faouder , Teresa Pérez-Berezo , Fabien Riols et al.
British Journal of Pharmacology, 2015, 172 (3), pp.910-923. ⟨10.1111/bph.12957⟩
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A link between hepatic glucose production and peripheral energy metabolism via hepatokines.

Aya Abdul-Wahed , Amandine Gautier-Stein , Sylvie Casteras , Maud Soty , Damien Roussel et al.
Molecular metabolism, 2014, 3 (5), pp.531-543. ⟨10.1016/j.molmet.2014.05.005⟩
Article dans une revue inserm-01350728 v1

Adverse effects of long-term exposure to bisphenol A during adulthood leading to hyperglycaemia and hypercholesterolemia in mice

Alice Marmugi , Frédéric Lasserre , Diane Beuzelin , Simon Ducheix , Laurence Huc et al.
Toxicology, 2014, 325, pp.133-143. ⟨10.1016/j.tox.2014.08.006⟩
Article dans une revue hal-02641668 v1

The liver X receptor: A master regulator of the gut-liver axis and a target for non alcoholic fatty liver disease

Simon Ducheix , Alexandra Montagner , Vassilia Theodorou , Laurent Ferrier , Hervé Guillou
Biochemical Pharmacology, 2013, 86 (1), pp.96 - 105. ⟨10.1016/j.bcp.2013.03.016⟩
Article dans une revue istex hal-02646839 v1

Essential fatty acids deficiency promotes lipogenic gene expression and hepatic steatosis through the liver X receptor.

Simon Ducheix , Alexandra Montagner , Arnaud Polizzi , Frédéric Lasserre , Alice Marmugi et al.
Journal of Hepatology, 2013, 58 (5), pp.984-92. ⟨10.1016/j.jhep.2013.01.006⟩
Article dans une revue istex inserm-00872314 v1

A systems biology approach to the hepatic role of the oxysterol receptor LXR in the regulation of lipogenesis highlights a cross-talk with PPARα.

Simon Ducheix , Normand Podechard , Frédéric Lasserre , Arnaud Polizzi , Aurélien Pommier et al.
Biochimie, 2013, 95 (3), pp.556-67. ⟨10.1016/j.biochi.2012.09.028⟩
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In vivo hepatic lipid quantification using MRS at 7 Tesla in a mouse model of glycogen storage disease type 1a

N. Ramamonjisoa , H. Ratiney , E. Mutel , Hervé Guillou , G. Mithieux et al.
Journal of Lipid Research, 2013, 54 (7), pp.2010-2022. ⟨10.1194/jlr.D033399⟩
Article dans une revue hal-00847703 v1
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Low Doses of Bisphenol A Induce Gene Expression Related to Lipid Synthesis and Trigger Triglyceride Accumulation in Adult Mouse Liver

Alice Marmugi , Simon Ducheix , Frédéric Lasserre , Arnaud Polizzi , Alain Paris et al.
Hepatology, 2012, 55 (2), pp.395-407. ⟨10.1002/hep.24685⟩
Article dans une revue hal-01019497 v1
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GW501516-activated PPARbeta/delta promotes liver fibrosis via p38-JNK MAPK-induced hepatic stellate cell proliferation.

Radina Kostadinova , Alexandra Montagner , Erwan Gouranton , Sébastien Fleury , Hervé Guillou et al.
Cell & Bioscience, 2012, 2 (1), pp.34. ⟨10.1186/2045-3701-2-34⟩
Article dans une revue inserm-00763884 v1
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The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans

.F. Benhamed , Pd Denechaud , C Robichon , M Moldes , J Girard et al.
Journal of Clinical Investigation, 2012, 122 (6), pp.2176-94. ⟨10.1172/JCI41636⟩
Article dans une revue hal-02649316 v1
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GPCR activation of Ras and PI3Kc in neutrophils depends on PLCb2/b3 and the RasGEF RasGRP4

Sabine Suire Sabine , Charlotte Lécureuil , Karen Anderson E , George Damoulakis George , Izabella Niewczas Izabella et al.
EMBO Journal, 2012, 31 (14), pp.3118-3129. ⟨10.1038/emboj.2012.167⟩
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P-glycoprotein Dysfunction Contributes to Hepatic Steatosis and Obesity in Mice

Magali Vignault-Foucaud , Zeina Soayfane , Cécile Menez-Berlioz , Justine Bertrand-Michel , Pascal Guy et al.
PLoS ONE, 2011, 6 (9), ⟨10.1371/journal.pone.0023614⟩
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Liver X Receptor: an oxysterol sensor and a major playerin the control of lipogenesis

Simon Ducheix , J.M.A. Lobaccaro , Pascal G.P. Martin , Hervé Guillou
Chemistry and Physics of Lipids, 2011, 164 (6), pp.500-14. ⟨10.1016/j.chemphyslip.2011.06.004⟩
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Cooperativity between Integrin Activation and Mechanical Stress Leads to Integrin Clustering.

Olivier Ali , Hervé Guillou , Olivier Destaing , Corinne Albiges-Rizo , Marc R. Block et al.
Biophysical Journal, 2011, 100 (11), pp.2595-604. ⟨10.1016/j.bpj.2011.03.028⟩
Article dans une revue inserm-00605002 v1

Regulation of LPCAT3 by LXR.

O. Demeure , Frédéric Lecerf , C. Duby , Colette Désert , S. Ducheix et al.
Gene, 2011, 470 (1-2), pp.7-11. ⟨10.1016/j.gene.2010.09.002⟩
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ELOVL2 controls the level of n-6 28:5 and 30:5 fatty acids in testis, a prerequisite for male fertility and spermmaturation in mice

Damir Zadravec , Petr Tvrdik , Hervé Guillou , Rilchard Haslam , Tsutomu Kobayash et al.
Journal of Lipid Research, 2011, 52 (2), pp.245-255. ⟨10.1194/jlr.M011346⟩
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Is Crohn's creeping fat an adipose tissue?

Isabelle Olivier , Vassilia Theodorou , Philippe Valet , Isabelle Castan-Laurell , Hervé Guillou et al.
Inflammatory Bowel Diseases, 2011, 17 (3), pp.747-57. ⟨10.1002/ibd.21413⟩
Article dans une revue inserm-00617823 v1
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P-glycoprotein Dysfunction Contributes to HepaticSteatosis and Obesity in Mice

Magali Vignault-Foucaud , Zeina Soayfane , Cécile Menez-Berlioz , Justine Bertrand-Michel , Pascal G.P. Martin et al.
PLoS ONE, 2011, 6 (9), pp.e23614
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PI3K beta Plays a Critical Role in Neutrophil Activation by Immune Complexes

Suhasini Kulkarni , Cassian Sitaru , Zoltan Jakus , Karen E. Anderson , George Damoulakis et al.
Science Signaling, 2011, 4 (168), pp.ra23. ⟨10.1126/scisignal.2001617⟩
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Ablation of the very-long-chain fatty acid elongase ELOVL3 in mice leads to constrained lipid storage and resistance to diet-induced obesity

Damir Zadravec , Annelie Brolinson , Rachel M. Fisher , Claes Carneheim , Robert I. Csikasz et al.
FASEB Journal, 2010, 24 (11), pp.4366 - 4377. ⟨10.1096/fj.09-152298⟩
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ARAP3 binding to phosphatidylinositol-(3,4,5)-trisphosphate depends on N-terminal tandem PH domains and adjacent sequences

Helen E. Craig , John Coadwell , Hervé Guillou , Sonja Vermeren
Cellular Signalling, 2010, 22 (2), pp.257-264. ⟨10.1016/j.cellsig.2009.09.025⟩
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FSH-stimulated PTEN activity accounts for the lack of FSH mitogenic effect in prepubertal rat Sertoli cells

Joëlle Dupont , Astrid Musnier , Jérémy Decourtye , Thomas Boulo , Charlotte Lécureuil et al.
Molecular and Cellular Endocrinology, 2009, 315 (1-2), pp.271. ⟨10.1016/j.mce.2009.09.016⟩
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Identification of potential mechanisms of toxicity after di-(2-ethylhexyl)-phthalate (DEHP) adult exposure in the liver using a systems biology approach

Alexandre Eveillard , Frédéric Lasserre , M de Tayrac , Arnaud Polizzi , S Claus et al.
Toxicology and Applied Pharmacology, 2009, 236 (3), pp.282-292. ⟨10.1016/j.taap.2009.02.008⟩
Article dans une revue istex hal-02662270 v1

Liver X receptor alpha regulates fatty acid synthase expression in chicken.

O. Demeure , C. Duby , Colette Désert , S. Assaf , Dominique Hazard et al.
Poultry Science, 2009, 88 (12), pp.2628-35. ⟨10.3382/ps.2009-00258⟩
Article dans une revue hal-00730008 v1
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A minimal model for hepatic fatty acid balance during fasting: Application to PPAR alpha-deficient mice

Pierre Blavy , Florence Gondret , Hervé Guillou , Sandrine Lagarrigue , P.G.P. Martin et al.
Journal of Theoretical Biology, 2009, 261 (2), pp.266. ⟨10.1016/j.jtbi.2009.07.025⟩
Article dans une revue hal-00559147 v1
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Di-(2-ethylhexyl)-phthalate (DEHP) activates the Constitutive Androstane Receptor (CAR): a novel signalling pathway sensitive to phthalates

Alexandre Eveillard , Laila Mselli-Lakhal , Ariane Mogha , Frédéric Lasserre , Arnaud Polizzi et al.
Biochemical Pharmacology, 2009, 77 (11), pp.1735. ⟨10.1016/j.bcp.2009.02.023⟩
Article dans une revue hal-00493499 v1

Transcriptional regulation of hepatic fatty acid metabolism

Hervé Guillou , Pg Martin , Thierry Pineau
Sub-cellular biochemistry, 2008, 49, pp.3-47
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Novel aspects of PPARα-mediated regulation of lipid and xenobiotic metabolism revealed through a nutrigenomic study

Pascal G.P. Martin , Hervé Guillou , Frédéric Lasserre , Sébastien Dejean , Annaig Lan et al.
Hepatology, 2007, 45 (3), pp.767-777. ⟨10.1002/hep.21510⟩
Article dans une revue hal-00661808 v1

Novel aspects of PPAR alpha-mediated regulation of lipid and xenobiotic metabolism revealed through a nutrigenomic study.

P.G.P. Martin , Hervé Guillou , F. Lasserre , S. Déjean , Annaig Lan et al.
Hepatology, 2007, 45, pp.667-677
Article dans une revue hal-02659352 v1
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Myristic acid increases $\Delta$6-desaturase activity in cultured rat hepatocytes

Sophie Jan , Hervé Guillou , Sabine d'Andrea , Stéphanie Daval , Monique Bouriel et al.
Reproduction Nutrition Development, 2004, 44 (2), pp.131-140. ⟨10.1051/rnd:2004020⟩
Article dans une revue hal-00900482 v1
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Distinct roles of endoplasmic reticulum cytochrome b5 and fused cytochrome b5-like domain for rat Δ6-desaturase activity

Hervé Guillou , Sabine d'Andrea , Vincent V. Rioux , Romain Barnouin , Stéphanie Dalaine et al.
Journal of Lipid Research, 2003, 45, pp.32 - 40. ⟨10.1194/jlr.m300339-jlr200⟩
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Effects of dietary fatty acids on the expression of an array of class II nuclear receptor target genes

P. Martin , Hervé Guillou , F. Lasserre , Cécile Calléja , Sophie Jan et al.
Drug Metabolism Reviews, 2003, 35 (178), pp.89
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Conversion of hexadecanoic acid to hexadecenoic acid by rat delta 6-desaturase

Hervé Guillou , Vincent V. Rioux , Daniel D. Catheline , Jean-Noel J.-N. Thibault , Monique Bouriel et al.
Journal of Lipid Research, 2003, 44 (3), pp.450-454. ⟨10.1194/jlr.C200019-JLR200⟩
Article dans une revue hal-02678861 v1
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Although it is rapidly metabolized in cultured rat hepatocytes, lauric acid is used for protein acylation

Vincent V. Rioux , Stéphanie Daval , Hervé Guillou , Sophie Jan , Philippe P. Legrand
Reproduction Nutrition Development, 2003, 43 (5), pp.419-430. ⟨10.1051/rnd:2003036⟩
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The same rat delta 6-desaturase not only acts on 18- but also on 24-carbon fatty acids in very-long-chain polyunsaturated fatty acid biosynthesis

Sabine d'Andrea , Hervé Guillou , Sophie Jan , Daniel D. Catheline , Jean-Noel J.-N. Thibault et al.
Biochemical Journal, 2002, 364, pp.49-55
Article dans une revue hal-02669429 v1

Hydrolysis of beta-casein by gastric proteases. 1. Comparison of proteolytic action of bovine chymosin and pepsin A

Hervé Guillou , Guy Miranda , J.P. Pelissier
International Journal of Peptide and Protein Research, 1991, 37, pp.494-501
Article dans une revue hal-02708181 v1
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Analyse quantitative des caséines dans le lait de vache par chromatographie liquide rapide d'échange d'ions (FPLC)

Hervé Guillou , G. Miranda , J.-P. Pelissier
Le Lait, 1987, 67 (2), pp.135-148
Article dans une revue hal-00929097 v1

Analyse quantitative des caseines dans le lait de vache par chromatographie liquide rapide d'echanges d'ions (FPLC)

Hervé Guillou , Guy Miranda , J.P. Pelissier
Lait, 1987, 67 (2), pp.135-148
Article dans une revue hal-02721649 v1

Analyse quantitative des caseines dans le lait de vache par chromatographie liquide rapide d'echange d'ions (FPLC)

Hervé Guillou , Guy Miranda , J.P. Pelissier
Lait, 1987, 67, pp.135-148
Article dans une revue hal-02719777 v1
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Méthodes de dosage des protéines du lait de vache

Hervé Guillou , J.P. Pelissier , R. Grappin
Le Lait, 1986, 66 (2), pp.143-175
Article dans une revue hal-00929062 v1

Methodes de dosage des proteines du lait de vache

Hervé Guillou , J.P. Pelissier , R. Grappin
Lait, 1986, 66, pp.143-175
Article dans une revue hal-02718097 v1

Study of genotoxic effects on exocrine pancreas after chronic dietary exposure to cocktail of pesticides

Camille Guyon , Clémence Rives , Céline Marie Pauline Martin , Hala Shalhoub , Noémie Poirier-Jaouen et al.
15th ICAW - International Comet Assay Workshop, Sep 2024, Rovinj, Croatia
Communication dans un congrès hal-04917625 v1
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Apport de l'imagerie MS dans le domaine de la toxicologie alimentaire

Justine Ferey , Loic Mervant , Emilien Jamin , Fabrice Pierre , Françoise Guéraud et al.
Journées annuelles du GDR-MSI, Jun 2024, Strasbourg (67), France
Communication dans un congrès hal-04634081 v1

Rôle de PPARα hépatocytaire dans le contrôle transcriptionnel de l’adaptation à un régime cétogène

Anne Fougerat , Arnaud Polizzi , Clothilde Marbach , Marion Régnier , Tiffany Fougeray et al.
Congrès de la Société Francophone du Diabète 2023, Mar 2023, Montpellier, France
Communication dans un congrès hal-04725860 v1

Effects of thermoneutral housing in a mouse model of non-alcoholic fatty liver disease

C.M.P. Martin , A. Polizzi , Valérie Alquier-Bacquié , F. Laserre , Marine Huillet et al.
59th Annual Meeting of the European Association for the Study of Diabetes (EASD), Oct 2023, Hamburg, Germany. pp.1007
Communication dans un congrès hal-04954521 v1

Rôle de PPARα hépatocytaire dans le contrôle transcriptionnel de l’adaptation à un régime cétogène

Anne Fougerat , Arnaud Polizzi , Clothilde Marbach , Marion Régnier , Tiffany Fougeray et al.
Congrès annuel de recherche translationnelle de la FHU IMPACT, Nov 2023, Toulouse, France
Communication dans un congrès hal-04725844 v1

Hepatocyte PPARα is required for the sensing of adipose-derived fatty acids and for full brown adipose tissue activation during lipolysis

Anne Fougerat , Gabriele Schoiswohl , Arnaud Polizzi , Marion Régnier , Carina Wagner et al.
58th annual meeting European Association for the Study of Diabetes, Sep 2022, Stockholm (Suède), Sweden
Communication dans un congrès hal-04725827 v1

Effets d’une exposition alimentaire, périnatale et chronique alimentaire, à des doses réglementaires de glyphosate sur l’axe microbiote intestinal-intestin-foie

Lorraine Smith , Céline Martin , Sabrine Naimi , Beatrice Engelmann , Frédéric Lasserre et al.
13ème congrès annuel de la Société Francophone de Santé et Environnement, Nov 2022, Valence, France
Communication dans un congrès hal-03775382 v1

Rôle de PPARα hépatocytaire dans le dialogue entre le foie et les tissus adipeux lors de la lipolyse

Anne Fougerat , Gabriele Schoiswohl , Arnaud Polizzi , Marion Régnier , Sarra Smati et al.
Congrès de la Société Francophone du Diabète 2022, Mar 2022, Nice, France
Communication dans un congrès hal-04725851 v1

Early life stress induces type 2 diabetes-like features in ageing mice

Hanna Ilchmann-Diounou , Maïwenn Olier , Corinne Lencina , Ambre Riba , Sharon Barretto et al.
NeuroGASTRO 2019 Congress, Sep 2019, Lisbon, Portugal. 1 p
Communication dans un congrès hal-02736934 v1

Sex dimorphic role of estrogen receptor a in physiological regulation of hepatic metabolism

Blandine Tramunt , Sarra Smati , Naia Grandgeorge , Anne Fougerat , Maxime Guillaume et al.
55. Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD), Sep 2019, Barcelona, Spain. 1 p
Communication dans un congrès hal-02734566 v1

Constitutive Androstane Receptor deficiency leads to sexually dimorphic metabolic disorders in aging

Céline Lukowicz , Marion Régnier , Frédéric Lasserre , Arnaud Polizzi , Alexandra Montagner et al.
54. Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD), European Association for the Study of Diabetes (EASD). GBR., Oct 2018, Berlin, France. pp.1
Communication dans un congrès hal-02735254 v1
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Hepatocyte PI3Kα controls the PPARα-FGF21 axis and regulates whole body fatty acid homeostasis

Marion Régnier , Arnaud Polizzi , Céline Lukowicz , S. Smati , Anne Fougerat et al.
European Assocation for the Study of Diabetes (EASD), Oct 2018, Berlin, Germany
Communication dans un congrès hal-04442612 v1

Hepatokines in metabolic disease: novel insights into FGF21 regulation by glucose

Catherine Postic , Alison Iroz , Alexandra Montagner , Fadila Benhamed , Arnaud Polizzi et al.
52. Annual Scientific Meeting of the European Society for Clinical Investigation “Precision medicine for healthy ageing”, May 2018, Barcelone, Spain. pp.1
Communication dans un congrès hal-02734271 v1

Influence of gender on progression of liver metabolic diseases in response to different nutritional challenges

Sarra Smati , Arnaud Polizzi , Marion Régnier , Alain Marrot , Céline Lukowicz et al.
54. Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD), European Association for the Study of Diabetes (EASD). GBR., Oct 2018, Berlin, Germany. pp.1
Communication dans un congrès hal-02735253 v1
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Intracellular lipids: an independent cause of liver injury and chronic kidney disease in non-alcoholic fatty liver disease-like context

Laure Monteillet , Monika Gjorgjieva , Marine Silva , Vincent Verzieux , Hervé Guillou et al.
G2L2, Oct 2018, Genève, Switzerland
Communication dans un congrès inserm-02388687 v1
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Hepatocyte PI3Kα controls the PPARα-FGF21 axis and regulates whole body fatty acid homeostasis

Marion Régnier , Arnaud Polizzi , Céline Lukowicz , Edwin Fouché , Frédéric Lasserre et al.
EMBO meeting, Apr 2017, Majorqua, Spain
Communication dans un congrès hal-04442626 v1
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Early life stress induces type 2 diabetes at adulthood in male mice

Hanna Ilchmann-Diounou , Maïwenn Olier , Corinne Lencina , Sandrine Ellero-Simatos , Ambre Riba et al.
10. International Meeting of Pediatric Endocrinology, Sep 2017, Washington, United States
Communication dans un congrès hal-01603069 v1
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Chronic maternal separation in mice impaired immuno-metabolism in older offspring on standard diet

Hanna Ilchmann-Diounou , Corinne Lencina , Sandrine Ellero-Simatos , Ambre Riba , Cherryl Harkat et al.
The Neonatal Window of Opportunity, Early Priming for Life, Herrenhausen Conference, Dec 2016, Hanovre, Germany
Communication dans un congrès hal-01608144 v1

Partial inhibition of hormone-sensitive lipase improves insulin sensitivity by induction of de novo lipogenesis and elongase ELOVL6 in human adipocytes

Pauline Morigny , Marianne Houssier , Sylvie Caspar Bauguil , Diane Beuzelin , Aline Mairal et al.
51. Annual Meeting of the European Association for the Study of Diabetes (EASD), European Association for the Study of Diabetes (EASD). Düsseldorf, GBR., Sep 2015, Stockholm, Sweden. 2 p
Communication dans un congrès hal-02744175 v1

Specific modulation of hepatic estrogen receptor alpha prevents fatty liver but also obesity and insulin resistance induced by a high fat diet in mice

Maeva Guillaume , Sandra Handgraaf , Isabelle Raymond-Letron , Aude Fabre , Elodie Riant et al.
50th International Liver Congress of the European-Association-for-the-Study-of-the-Liver, European Association for the Study of the Liver (EASL). Genève, CHE., Apr 2015, Vienne, Austria. 1 p
Communication dans un congrès hal-02743029 v1
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Contribution of the nuclear receptors PXR and CAR to gene expression modulations induced by fipronil in rodent liver

Béatrice Roques , Marlène Z. Lacroix , Nabila Moussaoui , Julien Leghait , Sylvie Puel et al.
12th International Congress of the European Association for Veterinary Pharmacology and Toxicology (EAVPT), Jul 2012, Noordwijkerhout, Netherlands. pp.1-182
Communication dans un congrès hal-02744689 v1

Contribution of the nuclear receptors PXR and CAR to gene expression modulations induced by fipronil in rodent liver

Béatrice Roques , Marlène Z. Lacroix , Nabila Moussaoui , Julien Leghait , Sylvie Puel et al.
4th Health Food Symposium, Pôle Aliment Sécurité Sanitaire & Santé (PA3S)., 2012, Toulouse, France
Communication dans un congrès hal-02802231 v1

Role of LXR in hepatic fatty acid homeostasis revealed through a nutrigenomic approach

Hervé Guillou
Journées des récepteurs nucléaires, Muséum National d’Histoire Naturelle (MNHN). Saisissez le nom du laboratoire, du service ou du département., Paris, FRA., Mar 2011, Paris, France
Communication dans un congrès hal-02802823 v1

Regulation of hepatic lipid metabolism: effect of dietary fatty acids and effect of Bisphenol A

Hervé Guillou
Centre de Génomique Integrative de Lausanne, Centre de Génomique Integrative de Lausanne., Feb 2011, Lausanne, Switzerland
Communication dans un congrès hal-02802819 v1

Regulation of hepatic lipid metabolism: effect of dietary fatty acids and effect of Bisphenol A.

Hervé Guillou
ENS Lyon, Ecole Normale Supérieure (ENS). Dr Hugo Aguilaniu, Lyon, FRA., Apr 2011, Lyon, France
Communication dans un congrès hal-02803044 v1

An xosysterol sensor and a master regulator of lipogenesis

Hervé Guillou
ENOR meeting, Saisissez le nom du laboratoire, du service ou du département., Ville service., Sep 2011, Rome, Italy
Communication dans un congrès hal-02802433 v1

L’expression d’une forme active de ChREBP conduit à la réinduction de la lipogenèse dans un modèle animal de déficience en LXR et SREBP-1c

A. Poupeau , F. Rayah-Benhamed , R. Dentin , Hervé Guillou , .J. Girard et al.
69èmes journées de l'Agence Française d’Etude du Foie, Saisissez le nom du laboratoire, du service ou du département., Ville service., Sep 2011, Paris, France
Communication dans un congrès hal-02804525 v1

ELOVL2 controls the level of n-628:5 and 30:5 fatty acids in testis, a prerequisite for male fertility and sperm maturation in mice

Damir Zadravec , Petr Tvrdik , Hervé Guillou , Richard Haslam , Tsutomu Kobayashi et al.
52. International Conference on the Bioscience of Lipids : Expanding the Horizons of Lipidomics, International Conference on the Bioscience of Lipids (ICBL). INT., Aug 2011, Varsovie, Poland. ⟨10.1016/j.chemphyslip.2011.05.035⟩
Communication dans un congrès hal-02747851 v1

Oxysterol signaling in fatty acid metabolism

Hervé Guillou
INSERM U915, L'institut du Thorax, Saisissez le nom du laboratoire, du service ou du département., Ville service., Jan 2011, Nantes, France
Communication dans un congrès hal-02802818 v1

Régulation du Liver X Receptor par le fructose et développement de la stéatose hépatique

Simon Ducheix , F Rayah-Benhamed , Alexandra Montagner , Arnaud Polizzi , Frédéric Lasserre et al.
9. Journées Francophones de Nutrition (JFN), Ville service., Dec 2011, Reims, France
Communication dans un congrès hal-02805683 v1

Rôle de LXR dans le métabolisme des acides gras

Hervé Guillou
Institut Cochin, Institut Cochin. Dr Catherine Postic, Ville service, FRA., Mar 2011, Cochin, France
Communication dans un congrès hal-02802820 v1
Image document

Integrating QTL controlling fatness, lipid metabolites and gene expressions to genetically dissect the adiposity complex trait in a meat chicken cross

Yuna Blum , Olivier O. Demeure , Colette Désert , Hervé Guillou , J Bertrand-Michel et al.
62. Annual Meeting of the European Association for Animal Production (EAAP), Aug 2011, Stavanger, Norway
Communication dans un congrès hal-02748764 v1

Power Allocation Problem in Charging Electric Vehicles with Photovoltaic Production

Hervé Guillou , Van-Dat Cung , Duy Long Ha , Mireille Jacomino
The 8th International Conference on Supply Chain Management and Information Systems (SCMIS2010), Oct 2010, Hong Kong, China. pp.720-725
Communication dans un congrès hal-00528686 v1

Nuclear receptors in the transcriptional control of hepatic fatty acid metabolism

Hervé Guillou
The Wenner-Gren Institute, University of Stockholm, Sep 2009, Stockholm, Sweden. pp.Inconnu
Communication dans un congrès hal-02813403 v1
Image document

A minimal and dynamic model for fatty acid metabolism in mouse liver

Pierre Blavy , Florence Gondret , Hervé Guillou , Sandrine Lagarrigue , Pascal G.P. Martin et al.
Journées Ouvertes de Biologie, Informatique et Mathématique (JOBIM), Jun 2008, Lille (FR), France
Communication dans un congrès hal-00729742 v1

A minimal and dynamical model for fatty acid metabolism in mouse liver

Pierre Blavy , Florence Gondret , Hervé Guillou , Sandrine Lagarrigue , Pascal G.P. Martin et al.
Journées Ouvertes Biologie Informatique Mathématiques, 2008, Lille, France. pp.Inconnu
Communication dans un congrès hal-02817340 v1

A kinetic view of coordinate modulations of gene expression and metabolism in wild-type and PPARa-/- mice during fasting

R Barnouin , Frédéric Lasserre , Michela Cantiello , Hervé Guillou , Thierry Pineau et al.
Gene signature symposia, 2005, Paris, France. pp.Inconnu
Communication dans un congrès hal-02828236 v1

PPARa remplit-il véritablement la fonction de senseur nutritionnel vis-à-vis des acides gras alimentaires ? Une étude comparée de signatures transcriptomique et lipidomique

Pascal G.P. Martin , Frédéric Lasserre , Hervé Guillou , R Barnouin , S Dejean et al.
Journée GERLI de lipidomique, 2005, Toulouse, France. pp.Inconnu
Communication dans un congrès hal-02829883 v1

Influence des acides gras alimentaires sur les voies de signalisation des récepteurs nucléaires : une étude comparée de signatures transcriptomique et lipidomique

Pascal G.P. Martin , Frédéric Lasserre , Hervé Guillou , R Barnouin , S Dejean et al.
Journées Scientifiques du GIS « PA-3S », 2005, Boussens, France. pp.Inconnu
Communication dans un congrès hal-02834051 v1

Empreintes transcriptionnelles de lipides alimentaires sur modèles souris

Pascal G.P. Martin , Hervé Guillou , Frédéric Lasserre , S Dejean , P Legrand et al.
Analyse intégrée de signatures variées GENOTOUL, 2005, Toulouse, France. pp.Inconnu
Communication dans un congrès hal-02825872 v1

A kinetic view of coordinate modulations of gene expression and metabolism in wild-type and PPARa-/- mice during fasting

Pgp Martin , R Barnouin , Frédéric Lasserre , Hervé Guillou , Michela Cantiello et al.
Cycles de conferences de l'IFR31, 2005, Toulouse, France. pp.Inconnu
Communication dans un congrès hal-02832532 v1

A kinetic view of coordinate modulations of gene expression and metabolism in wild type and PPARa-/- mice during fasting

R Barnouin , Frédéric Lasserre , M Cantielo , Hervé Guillou , Thierry Pineau et al.
Conference of the Paul Hamel Institute / New developements in the metabolic syndrome, 2004, Monaco, France. pp.Inconnu
Communication dans un congrès hal-02828078 v1

Biological effects of nutrients : what interdisciplinary strategies to grasp and analyze complex signatures

Pascal G.P. Martin , Frédéric Lasserre , Hervé Guillou , R Barnouin , S Dejean et al.
Journée d’animation du Département d’Alimentation Humaine de l’INRA, 2004, Paris, France. pp.Inconnu
Communication dans un congrès hal-02833182 v1

Characterization of hepatic effects induced by food lipids from the analysis of their biological signatures in mice

Pascal G.P. Martin , Hervé Guillou , Frédéric Lasserre , A Paris , S Dejean et al.
Journée d’animation du Département d’Alimentation Humaine de l’INRA, 2004, Paris, France. pp.Inconnu
Communication dans un congrès hal-02826237 v1

Is PPARa a true nutritional sensor for dietary fatty acids: a coordinate transcriptomic and lipidomic study

Pascal G.P. Martin , Frédéric Lasserre , Hervé Guillou , R Barnouin , S Dejean et al.
Journée d’animation scientifique de l’IFR31, 2004, Toulouse, France. pp.Inconnu
Communication dans un congrès hal-02829897 v1

Caractérisation des effets hépatiques induits par les lipides alimentaires par analyse de leurs signatures biologiques chez la souris

Pascal G.P. Martin , Hervé Guillou , Frédéric Lasserre , S Dejean , P Legrand et al.
Journée d’animation scientifique de l’IFR30, 2004, Toulouse, France. pp.Inconnu
Communication dans un congrès hal-02825956 v1

Expression and activity of two recombinant isoforms of rat NMT1

Vincent V. Rioux , Frédérique F. Pédrono , Stéphanie Daval , Daniel D. Catheline , Monique Bouriel et al.
6th Congress of International Society for the Study of Fatty Acids and Lipids (ISSFAL), Jun 2004, Brighton, United Kingdom
Communication dans un congrès hal-03348632 v1

Activité de la myristoyl-CoA: protéine N-myristoyltransférase de rat exprimée dans les cellules COS-7.

Vincent V. Rioux , M. Ravache , Etienne Cognard , Stéphanie Daval , Hervé Guillou et al.
Groupe d’Etude et de Recherche sur les Lipides et les Lipoprotéines (GERLI), Diversité moléculaire et physiopathologie, Sep 2003, Paris, France
Communication dans un congrès hal-03348639 v1

Effects of dietary fatty acids on the expression of an array of class II nuclear receptor target genes

Pascal G.P. Martin , Hervé Guillou , Frédéric Lasserre , Cécile Calléja , Sophie Jan et al.
Inconnu, 2003, pp.Inconnu
Communication dans un congrès hal-02833157 v1

Regulation of hepatic desaturases by PPAR alpha

Hervé Guillou , Pascal G.P. Martin , Sophie Jan , Sabine d'Andrea , Alain Roulet et al.
Inconnu, 2003, pp.Inconnu
Communication dans un congrès hal-02832865 v1

Effet des acides gras saturés sur l’activité et l’expression des D6- et D5-désaturases

Sophie Jan , Hervé Guillou , Sabine d'Andrea , Stéphanie Daval , Emmanuelle Dumont et al.
4èmes Journées Francophones de Nutrition, Nov 2002, Dijon, France
Communication dans un congrès hal-03348641 v1

Modelisation de la digestion gastrique des proteines du lait

Benedicte Savalle , P. Garnier , Guy Miranda , Hervé Guillou , J.P. Pelissier
Journee d'automne d'information scientifique, Oct 1987, Jouy-en-Josas, France
Communication dans un congrès hal-02783241 v1

Transcriptional regulation of hepatic fatty acid metabolism

Hervé Guillou , Pgp Martin , Thierry Pineau
Subcellular Biochemistry: Lipids in Health and Disease, Springer, 2009
Chapitre d'ouvrage hal-02815951 v1