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Isabelle Fournier

Professor Senior Member Institut Universitaire de France Vice President for Doctoral Research at University of Lille
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Présentation

Prof. Fournier is Distinguished Professor at University of Lille, and she holds a position as co-director of the PRISM Inserm U1192 Lab and as Vice President for Doctoral Research for the university. She is a bioanalytical chemist specialized in clinical mass spectrometry and proteomics. She started research working on fundamental of MALDI during her PhD at University Pierre & Marie Curie in Paris first and then, as a postdoctoral fellow within the group of Prof. Michael Karas in Frankfurt. In 2002, she established her own group at University of Lille where she started developing MALDI MS Imaging. She contributed to the field with several developments including strategies for imaging of FFPE tissues and proteins, and the development of tagged probes for specific imaging of mRNA and antigens. In 2009, she was hired as Full Professor and awarded a Junior position at Institut Universitaire de France. Since 2012, she got interested by the development of Spatially Resolved Proteomics in combination to MALDI MSI for applications in oncology. Over the past 5 years, she also worked on the development of in vivo MS for guided surgery and intraoperative analysis. She confounded the Imabiotech Company which provides services in MALDI MSI and recently CELEOS that will commercialize the SpiderMass technology. She was recently distinguished by the international distinguish award from MSACL and was awarded a senior position at Institut Universitaire de France in 2019.

Domaines de recherche

Chimie analytique Génomique, Transcriptomique et Protéomique [q-bio.GN] Imagerie

Compétences

mass spectrometry imaging proteomics spatial proteomics lipidomics health technology

Publications

"antonella-raffo-romero"

Correction: Heimdall, an alternative protein issued from a ncRNA related to kappa light chain variable region of immunoglobulins from astrocytes: a new player in neural proteome

Alice Capuz , Sylvain Osien , Tristan Cardon , Mélodie Anne Karnoub , Soulaimane Aboulouard
Cell Death and Disease, 2023, 14 (10), pp.677. ⟨10.1038/s41419-023-06143-x⟩
Article dans une revue hal-04278155v1
Image document

Location of neonatal microglia drives small extracellular vesicles content and biological functions in vitro

Adriana-Natalia Murgoci , Marie Duhamel , Antonella Raffo-Romero , Khalil Mallah , Soulaimane Aboulouard
Journal of Extracellular Vesicles, 2020, 9 (1), pp.1727637. ⟨10.1080/20013078.2020.1727637⟩
Article dans une revue inserm-02941810v1

Mapping Spatiotemporal Microproteomics Landscape in Experimental Model of Traumatic Brain Injury Unveils a link to Parkinson's Disease

Khalil Mallah , Jusal Quanico , Antonella Raffo-Romero , Tristan Cardon , Soulaimane Aboulouard
Molecular and Cellular Proteomics, 2019, 18 (8), pp.1669-1682. ⟨10.1074/mcp.RA119.001604⟩
Article dans une revue inserm-02941592v1

Matrix-Assisted Laser Desorption/Ionization-Mass Spectrometry Imaging of Lipids in Experimental Model of Traumatic Brain Injury Detecting Acylcarnitines as Injury Related Markers

Khalil Mallah , Jusal Quanico , Antonella Raffo-Romero , Tristan Cardon , Soulaimane Aboulouard
Analytical Chemistry, 2019, 91 (18), pp.11879-11887. ⟨10.1021/acs.analchem.9b02633⟩
Article dans une revue inserm-02941587v1
Image document

Spatially-Resolved Top-down Proteomics Bridged to MALDI MS Imaging Reveals the Molecular Physiome of Brain Regions

Vivian Delcourt , Julien Franck , Jusal Quanico , Jean-Pascal Gimeno , Maxence Wisztorski
Molecular and Cellular Proteomics, 2018, 17 (2), pp.357-372. ⟨10.1074/mcp.M116.065755⟩
Article dans une revue inserm-02941492v1

Deciphering molecular consequences of the proprotein convertase 1/3 inhibition in macrophages for application in anti-tumour immunotherapy

Franck Rodet , Alice Capuz , Tsukasa Hara , Rinaldo van Meel , Marie Duhamel
Journal of Biotechnology, 2018, 282, pp.80-85. ⟨10.1016/j.jbiotec.2018.07.002⟩
Article dans une revue hal-04445717v1
Image document

3D MALDI mass spectrometry imaging reveals specific localization of long-chain acylcarnitines within a 10-day time window of spinal cord injury

Jusal Quanico , Lena Hauberg-Lotte , Stephanie Devaux , Zahra Laouby , Celine Meriaux
Scientific Reports, 2018, 8 (1), pp.16083. ⟨10.1038/s41598-018-34518-0⟩
Article dans une revue inserm-02940797v1