
Isabelle Luron
Présentation
Director of Research (H-index 42) Current position at the NuMeCan Institute, INRA, INSERM, University of Rennes Team ‘EAT’ 16 Le Clos 35590 Saint-Gilles FRANCE Research interests in nutrition and gut physiology, in the area of gut-brain dialogue upon food transition*, i.e. the impact of perinatal nutritional environment on the gut-brain axis and microbiota colonisation, and long term consequences on gut-brain functioning and sensitivity to stress (programming). Participant of European Projects: 2020-2025: H2020-INFRAIA-2020-1 PIGWEB An infrastructure for experimental research for sustainable pig production 2009-2012: FP7 KBBE-2008-2b-227509 INTERPLAY 2004-2008: FP6-2002-Food-1-506144 « Feed for Pig Health » Development of Natural Alternatives to Anti-microbials for The Control of Pig Health and Promotion of Performance 2001-2004: QLK5-CT-2000-00522 « Healthypigut » Defining and validating gut health criteria in young pigs, based on digestive physiology, microbiology and mucosal immunology investigations for testing alternative strategies to in-feed antibiotics Participant of ANR projects (Porcinet, PNRA) and > 30 collaborative contracts with industrials in last 10 y.
Domaines de recherche
Compétences
Publications
Publications
Protein ingredient quality of infant formulas impacts gut physiology and microbiota in mini-piglets used as a human infant model.https://espghancongress.org/. 56th Annual Meeting of ESPGHAN 2024, May 2024, Milan, Italy. , 2024
Poster de conférence
hal-04582804
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Protein ingredient quality of infant formulas impacts gut physiology and microbiota in mini-piglets used as a human infant model56th Annual meeting of European Society for Paediatric Gastroenterology Hepatology and Nutrition (ESPGHAN), May 2024, Milan, Italy
Poster de conférence
hal-04779997
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Protein ingredient quality within infnat formulas impacts digestion and amino acid bioavailability: a combined in vitro and in vivo approachADSA annual meeting 2023, Jun 2023, Ottawa, Canada. , Journal of Dairy Science, 106 (supplement 1), pp.337-338, 2023, Abstracts of the 2023 American Dairy Science Association® Annual Meeting
Poster de conférence
hal-04155468
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Two human milk synthetic bacterial community exhibited contrasted impacts on intestinal immune and barrier function in vitroInternational Milk Genomic Consortium Annual Symposium, Sep 2023, Cork, Ireland
Poster de conférence
hal-04885470
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Protein ingredient quality and structure of infant formulas impact plasma amino acid kinetics in pigletshttps://espghancongress.org/. 55th Annual meeting of the European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN), May 2023, Vienne, Austria. , 2023
Poster de conférence
hal-04159876
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La qualité des ingrédients protéiques laitiers impacte la physiologie intestinale et le microbiote d’un modèle animal du nourrissonhttps://www.lesjfn.fr/expo. Journées Francophones de Nutrition (JFN), Dec 2023, Marseille, France. , 2023
Poster de conférence
hal-04353506
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In vitro infant digestion model leads to similar conclusion as in vivo study: focus on human milk and infant formula protein digestionADSA annual meeting 2023, Jun 2023, Ottawa, Canada. , Journal of Dairy Science, 106 (supplement 1), pp.332, 2023, Abstracts of the 2023 American Dairy Science Association® Annual Meeting
Poster de conférence
hal-04155575
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Impact of neonatal digestion on the physiology of breast milk bacteria and their immunomodulation capacitieshttps://cbl2022.colloque.inrae.fr/cbl-2022. Colloque du Club des Bactéries Lactiques 23ème édition, Jun 2022, Rennes, France. , 12, 2022, ⟨10.3390/nu12041039⟩
Poster de conférence
hal-04318063
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Protein structure within infant milk formulas impact their in vitro dynamic digestion.https://www.univ-rennes.fr/evenements-0/journees-scientifiques-ed-egaal. Journée Scientifiques de l’école doctorale EGAAL, Jun 2022, Rennes, France. , 2023
Poster de conférence
hal-04159921
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Qualité nutritionnelle des protéines du lait humain et d’une préparation pour nourrissons, étude pré-clinique chez le modèle mini-porceletJournées francophones de Nutrition 2022, Nov 2022, Toulouse, France. , 2022
Poster de conférence
hal-03864937
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La structure des protéines dans les préparations pour nourrisson impacte leur digestion in vitro.Congrès des Sociétés de Pédiatrie, Jun 2022, Lille, France. 2023
Poster de conférence
hal-04158758
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Comparaison of dynamic in vitro digestion of human milk vs standard infant formula to better understand their digestive kinetics7th International Conference on Food Digestion (ICFD2022), May 2022, Cork, Ireland. 2022
Poster de conférence
hal-03662104
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Immunomodulatory potential of bacteria isolated from human breast milk on different cellular models23ème édition du colloque du Club des Bactéries Lactiques, Jun 2022, Rennes, France. , 2022
Poster de conférence
hal-03694103
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Standardized ileal digestibility of amino acids and nitrogen in human milk and infant formula – an in vivo study7th International Conference of Food Digestion (ICFD 2022), May 2022, Cork, Ireland. 2022
Poster de conférence
hal-03662139
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Machine Learning classification performance on mechanistic representations of the gut microbiota built from abundance profilesJournées Ouvertes en Biologie, Informatique et Mathématiques (JOBIM), Jul 2022, Rennes, France. , pp.181, 2022, Proceedings
Poster de conférence
hal-04155624
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La structure des préparations pour nourrissons module leur cinétique digestive : approche in vitro et in vivoJournées Francophones de Nutrition, Nov 2022, Toulouse, France. , 2022
Poster de conférence
hal-03865009
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Post-natal development of the ghrelin system and impact of medium-chain fatty acid-enriched formula feeding in Yucatan mini-pigsResearch Congress on Eating Disorder, Sep 2019, Paris, France
Poster de conférence
hal-02943030
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Développement post-natal du système ghréline et impact d’une formule infantile enrichie en acides gras à chaine moyenne chez le mini-porc Yucatan.Journées Francophones de Nutrition, Sep 2019, Rennes, France. , pp.P214
Poster de conférence
hal-02946488
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La matière grasse laitière et le probiotique L. fermentum incorporés dans des préparations pour nourrissons modulent leur digestion ainsi que la composition du microbiote et les propriétés barrière de l’intestin chez le mini-porcLes Journées Francophones de Nutrition, Nov 2018, Nice, France. , 2018
Poster de conférence
hal-01946277
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Une supplémentation précoce en fructooligosaccharides à courte chaîne (FOScc) stimule la maturation du système immunitaire intestinal des porcelets allaités et améliore la réactivité immunitaire ultérieure50. Journées de la Recherche Porcine, Feb 2018, Paris, France. IFIP - Institut du Porc, Journées de la Recherche Porcine en France, 2018, Journées de la Recherche Porcine en France
Poster de conférence
hal-01714761
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Early prebiotic supplementation induces long-lasting consequences on microbiota composition and metabolic health in adult pigs consuming an unbalanced diet5. International Conference on Food Digestion, Apr 2017, Rennes, France. , 2017, Proceedings of the 5th International Conference on Food Digestion
Poster de conférence
hal-01595246
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An intestinal transcriptome analysis in fetal pigs reveals genes involved in glucose and lipid metabolism and immunity as valuable clues of maturity at birth50. Annual Meeting of the European Society for Pediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN), May 2017, Prague, Czech Republic. , 64 (Suppl. 1), 2017, Journal of Pediatric Gastroenterology and Nutrition
Poster de conférence
hal-01575939
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Neonatal modulation of gut digestion and microbiota by addition of dairy lipids and probiotic L. fermentum CECT 5716 in infant formula programs adult gut microbiota and physiology in a minipig model5. International Conference on Food Digestion, Apr 2017, Rennes, France. , 2017, Proceedings of the 5th International Conference on Food Digestion
Poster de conférence
hal-01545650
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Addition of dairy lipids and probiotic Lactobacillus fermentum CECT 5716 in infant formula programs gut microbiota, epithelial permeability, immunity and GLP-1 secretion in adult minipigs50. Annual Meeting of the European Society for Pediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN), May 2017, Prague, Czech Republic. , Journal of Pediatric Gastroenterology and Nutrition, 64 (Suppl. 1), 2017, Journal of Pediatric Gastroenterology and Nutrition
Poster de conférence
hal-01595024
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La matière grasse laitière et le probiotique L. fermentum CECT 5716 incorporés dans des formules infantiles programment la composition du microbiote et la fonction endocrine intestinale dans un modèle miniporc17. Journées Francophones de Nutrition (JFN), Dec 2017, nantes, France. , 2017, Livre des résumés
Poster de conférence
hal-01688924
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Microbiota can be affected by the lipid composition of infant formulas49. Annual meeting of the european society for paediatric gastroenterology, hepatology and nutrition (ESPGHAN), May 2016, Athènes, Greece. , Journal of Pediatric Gastroenterology and Nutrition, 62 - suppl. 1, 2016, Journal of Pediatric Gastroenterology and Nutrition
Poster de conférence
hal-01413552
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Maternal diet effects during the perinatal period on cognitive and hedonic brain processes and metabolism of adult Yucatan minipigs Tests on obese adults Test on lean adultsInternational Conference on Obesity and Chronic Disease (ICOCD 2016), Jul 2016, Las Vegas, United States
Poster de conférence
hal-02865369
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L’incorporation de matière grasse laitière et L. fermentum CECT 5716 dans des formules infantiles modifie les fonctions barrière et immunitaire intestinales sans effet sur les conséquences métaboliques d’un régime hyperénergétique chez le miniporc adulte16. Journées Francophones de Nutrition (JFN), Nov 2016, Montpellier, France. 2016, Livre des résumés
Poster de conférence
hal-01595026
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BAC treatment of the rectosigmoid in piglet: a reproducible model of partial aganglionnosis ina large animal49. Annual meeting of the european society for paediatric gastroenterology, hepatology and nutrition (ESPGHAN), May 2016, Athènes, Greece. , Journal of Pediatric Gastroenterology and Nutrition, 62 - suppl. 1, 2016, Journal of Pediatric Gastroenterology and Nutrition
Poster de conférence
hal-01413539
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Impacts of the structure of infant formulas on their digestive behaviour and hydrolysis: insights from in vitro studies and comparison with human milk49. Annual Meeting of the European Society for Paediatric Gastroenterology, Hepatology and Nutrition, May 2016, Athènes, Greece. 2016
Poster de conférence
hal-02743141
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Impact of food additive (prebiotic) and food contaminant (mycotoxin) in the maternal diet onto the ontogenesis and responsiveness of mucosal immune systemIAD 2016 - 10. Journées du Réseau Français "Immunologie des animaux domestiques", Mar 2016, Ploufragan, France. 51 p., 2016
Poster de conférence
hal-01527067
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Early digestive microbiota characteristics is correlated to susceptibility to post-weaning diarrhea13. Digestive physiology of pigs, May 2015, Varsovie, Poland. , 2015, Book of abstracts
Poster de conférence
hal-01575940
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Dysregulation of sirtuins and key metabolic genes in skeletal muscle of pigs with intrauterine growth restriction is associated to alterations of circulating IGF-151st Annual Meeting of the European Association for the Study of Diabetes (EASD), 2015, NA, France. Springer Link, Diabetologia, 58 (Suppl. 1), 2015, Diabetologia
Poster de conférence
hal-01205625
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Un régime hyperlipidique entraîne des désordres métaboliques sans modification de la composition corporelle chez le porc conventionnel adulte12. Journées Francophones de Nutrition (JFN), Dec 2014, Bruxelles, Belgique. , Nutrition Clinique et Métabolisme, 28 suppl 1, 2014, Nutrition Clinique et Métabolisme
Poster de conférence
hal-01594210
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Addition of milk fat in infant formula impacts neonatal gut microbiotaThe 11. Biennial ISSFAL Congress 2014, Jun 2014, Stockholm, Sweden. 2014
Poster de conférence
hal-01209668
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Milk lipids in infant formulas modify the proteolysis, microbiota and intestinal physiology in neonatal pigletsThe 11. Biennial ISSFAL Congress 2014, Jun 2014, Stockholm, Sweden. 2014
Poster de conférence
hal-01209667
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La matière grasse laitière dans les formules infantiles modifie la digestion des protéines, le microbiote et la physiologie intestinale chez le porcelet nouveau-né.Congrès national de la société française de pédiatrie, May 2014, Lyon, France. 2014
Poster de conférence
hal-01408009
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An insight into the interfacial composition and susceptibility to digestion of model infant formulas stabilized by milk polar lipidsThe 11. Biennial ISSFAL Congress 2014, Jun 2014, Stockholm, Sweden. , 2014
Poster de conférence
hal-01209666
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Des approches multi-omiques pour caractériser la fin du développement foetal et mieux comprendre le déterminisme de la maturité à la naissance en lien avec la survie néonatale46. Journées de la Recherche Porcine, Feb 2014, Paris, France. IFIP - Institut du Porc, Journées de la Recherche Porcine en France, 46, 2014, Journées de la Recherche Porcine en France
Poster de conférence
hal-01173389
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Perinatal antibiotic treatment of sows affects intestinal barrier and immune system in offspring64. Annual Meeting of the European Federation of Animal Science (EAAP), Aug 2013, Nantes, France. Wageningen Academic Publishers, Annual Meeting of the European Association for Animal Production, 19, 2013, Annual Meeting of the European Association for Animal Production
Poster de conférence
hal-01594212
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Does the structure of infant formula and human milk influence their digestibility?Food Structures, Digestion and Health International Conference, Oct 2013, Melbourne, Australia. 2013
Poster de conférence
hal-01209543
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Supplementation of the maternal diet with linolenic acid (C18:3 n-3) modifies piglet gut immune system education towards LPS46. Annual meeting of the european society for paediatric gastroenterology, hepatology and nutrition (ESPGHAN), May 2013, Londres, United Kingdom. , Journal of Pediatric Gastroenterology and Nutrition, 56 - Suppl. 2, 2013, Journal of Pediatric Gastroenterology and Nutrition
Poster de conférence
hal-01413557
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Comment la structuration des matrices alimentaires affecte la biodisponibilité des nutriments? Formules infantiles et digestibilitéJournées francophones de nutrition, Dec 2013, Bordeaux, France. 2013
Poster de conférence
hal-01209550
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Effets d’une supplémentation alimentaire peri‐partum en fructo‐oligosaccharides à chaînes courtes sur le statut immunitaire et les performances de croissance des porcelets45. Journées de la Recherche Porcine, Feb 2013, Paris, France. IFIP - Institut du Porc, Journées de la Recherche Porcine en France, 45, 2013, 45èmes journées de la recherche porcine
Poster de conférence
hal-02745950
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Introduction of milk phospholipids and lipids in infant formula promotes the intestinal immune system maturation in neonatal piglets2 International Conference on Food Digestion, Mar 2013, Madrid, Spain. , 2013
Poster de conférence
hal-01209430
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Introduction of milk phospholipids and lipids in infant formula promotes the intestinal immune system maturation in neonatal pigletsFood Structures, Digestion and Health International Conference, Oct 2013, Melbourne, Australia. , 2013
Poster de conférence
hal-01209542
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A maternal scFOS supplementation modulates maturation of the immune system of piglets64. Annual Meeting of the European Federation of Animal Science (EAAP), Aug 2013, Nantes, France. Wageningen Academic Publishers, Annual Meeting of the European Association for Animal Production, 19, 2013, Annual Meeting of the European Association for Animal Production
Poster de conférence
hal-01594360
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A multi-tissue analysis in fetal pigs to identify genes involved in the determinism of maturity and survival at birth9th Intenational Conference on Pig Reproduction (ICPR), Jun 2013, Olsztyn, Poland. , 2013, Programm and Abstract Book
Poster de conférence
hal-02749790
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Effects of sow antibiotic treatment and offspring diet on microbiota and gut barrier throughout life64. Annual Meeting of the European Federation of Animal Science (EAAP), Aug 2013, Nantes, France. Wageningen Academic Publishers, Annual Meeting of the European Association for Animal Production, 19, 2013, Annual Meeting of the European Association for Animal Production
Poster de conférence
hal-01594362
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Impact of Casein / Whey proteins (Cns/WPs) ratio of infant formulas on in vivo protein digestion and gut physiology1 st international conference on Food Digestion, Mar 2012, Cesena, Italy. Cost Infogest, 2012
Poster de conférence
hal-01209325
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Presence of milk phospholipids and milk lipids modified the immunomodulatory properties of infant formula in neonatal pigs4th World Congress of Pediatric Gastroenterology, Hepatology and Nutrition, Nov 2012, Taïpei, Taiwan. , 2012, Abstract book
Poster de conférence
hal-01454222
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Infant formula: effect of heat treatment and composition on physical characteristics and nutritional composition of powders, and biochemistry of proteins5. International Symposium on Spray Dried Dairy Products, Jun 2012, Saint Malo, France. , 2012
Poster de conférence
hal-01209389
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Peri-partum scFOS supplementation improves intestinal mucosal immune response of the offspring4th World Congress of Pediatric Gastroenterology, Hepatology and Nutrition, Nov 2012, Taïpei, Taiwan. , 2012, Abstract Book
Poster de conférence
hal-02744682
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Characterization of the placental development in the intrauterine growth-retarded pigletColloque SF-DOHaD, Nov 2012, Paris, France. Cambridge University Press, Journal of Developmental Origins of Health and Disease, 4 (Supplement 1), 2013, Founding meeting of SF-DOHAD
Poster de conférence
hal-02748225
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Characterization of the placental development in the intra-uterine growth retarded pigletInternational Federation of Placenta Associations Meeting 2012, Sep 2012, Hiroshima, Japan. W B SAUNDERS CO LTD, Placenta, 33, pp.137, 2012, Abstracts for the International Federation of Placenta Associations Meeting 2012. ⟨10.1016/j.placenta.2012.06.016⟩
Poster de conférence
istex
hal-02747691
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La supplémentation du régime maternel en C18 : 3n-3 modifie l'éducation du système immunitaire intestinal vis-à-vis du LPS chez le porcelet10. Journées francophones de nutrition (JFN), Dec 2012, Lyon, France. , 2012, 10èmes journées francophone de nutrition
Poster de conférence
hal-01210346
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La supplémentation en Scfos du régime maternel en peri-partum modifie la qualité immune du colostrum et le développement du système immunitaire intestinal des porcelets9. Journées Francophones de Nutrition (JFN), Dec 2011, Reims, France. Elsevier Mason SAS, Nutrition Clinique et Métabolisme, 25 (Suppl. 2), 1 p., 2011, 9ème Journées francophones de nutrition
Poster de conférence
hal-02744566
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Peri-partum scFOS supplementation modifies colostrum immune quality and intestinal immune system development of the offspring2nd International Symposium Microbes for Health, Dec 2011, Paris, France. 2011
Poster de conférence
hal-02806561
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Validation of air displacement plethysmography for body composition in living pigletsAnnual meeting of pediatric academic societies, May 2010, Vancouver, Canada. 2011
Poster de conférence
hal-02807171
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In vivo digestion of infant formula in piglets: protein digestion kinetics and their potential bioactivityBiopolymères 2010, Matrices alimentaires : Construction, déconstruction, propriétés sensorielles et nutritionnelles, Dec 2010, Le croisic, France. , 2010
Poster de conférence
hal-01190811
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Effects of CCK and gastrin on pancreatic secretion in vivo in the calfAnnual symposium on animal and human nutrition, Oct 1996, Nantes, France. 1997
Poster de conférence
hal-02837377
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Regulation of bovine pancreatic elastase II expression during ontogenyAnnual symposium on animal and human nutrition, Oct 1996, Nantes, France. 1997
Poster de conférence
hal-02834343
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Response of growth hormone and insulin regulatory axes and instestinal mucosal function to protein in milk substitutes for baby pig as a model for human baby[Contract] 2007
Rapport
(rapport contrat/projet)
hal-02815344
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Régulation de la fonction pancréatique chez le veau et le porcSciences du Vivant [q-bio]. Université de Rennes 1, 2001
HDR
tel-02831816
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The role of gut hormones in adaptation to life after birthSymposium on the developmental process from ovocytes to newborn in pigs and calves, 2001, Copenhagen, Denmark. n.p., 2001
Proceedings/Recueil des communications
hal-02826451
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Effects of different colostrum intake on morphology, cell proliferation and enzyme activities in the gut of neonatal calves14. Meeting of the Fachgruppe physiologie und biochemie der deutschen veterin"rmedizinischen, Apr 2000, Munich, Germany. n.p., 2000
Proceedings/Recueil des communications
hal-02838266
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La gastrine via les récepteurs CCKB/gastrine (CCKB/G) pancréatiques stimule la synthèse protéique et active la voie PI3 kinase et P70 S6 kinaseRéunion annuelle du club d'études des cellules epithéliales digestives, Jan 1999, Bruxelles, Belgique. n.p., 1999
Proceedings/Recueil des communications
hal-02842624
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Effects of age and food on exocrine pancreatic function and some regulatory aspectsSatellite symposium, Aug 1999, Zurich, Switzerland. n.p., 1999
Proceedings/Recueil des communications
hal-02835123
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Influence of age and food on digestive secretionFrench-Polish symposium on development of adaptations in the gastrointestinal tract and in the whole body in growing animals regarding food utilization and health, Jun 1998, Paris, France. n.p., 1998
Proceedings/Recueil des communications
hal-02835222
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Regulation de la synthese des enzymes pancreatiques au cours du developpement postnatal et du sevrage chez le veau. Sequences de quelques enzymesSciences du Vivant [q-bio]. Université de Rennes 1, 1990. Français. ⟨NNT : ⟩
Thèse
tel-02851421
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