Ivan Mikaelian

21
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Publications

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The endoplasmic reticulum pool of Bcl-xL prevents cell death through IP3R-dependent calcium release

Rudy Gadet , Lea Jabbour , Trang Thi Minh Nguyen , Olivier Lohez , Ivan Mikaelian et al.

Cell Death Discovery, 2024, 10, pp.346. ⟨10.1038/s41420-024-02112-1⟩

Article dans une revue hal-04675577v1
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Viruses traverse the human proteome through peptide interfaces that can be biomimetically leveraged for drug discovery

Laurène Meyniel-Schicklin , Jérôme Amaudrut , Pierre Mallinjoud , Fabrice Guillier , Philippe E Mangeot et al.

Proceedings of the National Academy of Sciences of the United States of America, 2024, 121 (5), pp.e2308776121. ⟨10.1073/pnas.2308776121⟩

Article dans une revue hal-04411218v1
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Pericyte stem cells induce <scp>Ly6G</scp> <sup>+</sup> cell accumulation and immunotherapy resistance in pancreatic cancer

Zhichong Wu , Kevin Thierry , Sophie Bachy , Xinyi Zhang , Pia Gamradt et al.

EMBO Reports, 2023, ⟨10.15252/embr.202256524⟩

Article dans une revue hal-04047023v1
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Nrh L11R single nucleotide polymorphism, a new prediction biomarker in breast cancer, impacts endoplasmic reticulum-dependent Ca2+ traffic and response to neoadjuvant chemotherapy

Minh Quang Duong , Rudy Gadet , Isabelle Treilleux , Stéphane Borel , Adrien Nougarède et al.

Cell Death and Disease, 2023, 14, pp.392. ⟨10.1038/s41419-023-05917-7⟩

Article dans une revue hal-04185345v1
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Mitochondrial Bcl-xL promotes brain synaptogenesis by controlling non-lethal caspase activation

Trang Thi Minh Nguyen , Rudy Gadet , Marine Lanfranchi , Romane Lahaye , Sozerko Yandiev et al.

iScience, 2023, 26 (5), pp.106674. ⟨10.1016/j.isci.2023.106674⟩

Article dans une revue hal-04121358v1
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A minimal standardized human bone marrow microphysiological system to assess resident cell behavior during normal and pathological processes

Thibault Voeltzel , Gaëlle Fossard , Michaël Degaud , Kevin Geistlich , Nicolas Gadot et al.

Biomaterials Science, 2022, 10 (2), pp.485-498. ⟨10.1039/d1bm01098k⟩

Article dans une revue hal-03758030v1
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EGFR-dependent aerotaxis is a common trait of breast tumour cells

Ivan Mikaelian , Rudy Gadet , Mathieu Deygas , Philippe Bertolino , Ana Hennino et al.

Journal of experimental & clinical cancer research, 2022, 41 (1), pp.324. ⟨10.1186/s13046-022-02514-y⟩

Article dans une revue hal-04045454v1
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Mitochondrial morphodynamics alteration induced by influenza virus infection as a new antiviral strategy

Irene Pila-Castellanos , Diana Molino , Joe Mckellar , Laetitia Lines , Juliane da Graca et al.

PLoS Pathogens, 2021, 17, ⟨10.1371/journal.ppat.1009340⟩

Article dans une revue hal-03439550v1
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Hypoxia triggers collective aerotactic migration in Dictyostelium discoideum

Olivier Cochet-Escartin , Mete Demircigil , Satomi Hirose , Blandine Allais , Philippe Gonzalo et al.

eLife, 2021, 10, pp.e64731. ⟨10.7554/elife.64731⟩

Article dans une revue hal-02997747v2
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The apoptosis inhibitor Bcl-xL controls breast cancer cell migration through mitochondria-dependent reactive oxygen species production

Margaux Bessou , Jonathan Lopez , Rudy Gadet , Mathieu Deygas , Nikolay Popgeorgiev et al.

Oncogene, 2020, 39 (15), pp.3056-3074. ⟨10.1038/s41388-020-1212-9⟩

Article dans une revue hal-03094820v1
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PRMT1 Is Critical for the Transcriptional Activity and the Stability of the Progesterone Receptor.

Lucie Malbeteau , Coralie Poulard , Cécile Languilaire , Ivan Mikaelian , Frederic Flamant et al.

iScience, 2020, 23 (6), pp.101236. ⟨10.1016/j.isci.2020.101236⟩

Article dans une revue hal-03019840v1

Breast Cancer Targeting through Inhibition of the Endoplasmic Reticulum-Based Apoptosis Regulator Nrh/BCL2L10

Adrien Nougarede , Nikolay Popgeorgiev , Loay Kassem , Soleilmane Omarjee , Stephane Borel et al.

Cancer Research, 2018, 78 (6), pp.1404-1417. ⟨10.1158/0008-5472.CAN-17-0846⟩

Article dans une revue hal-02373767v1
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Redox regulation of EGFR steers migration of hypoxic mammary cells towards oxygen

Mathieu Deygas , Rudy Gadet , Germain Gillet , Ruth Rimokh , Philippe Gonzalo et al.

Nature Communications, 2018, 9 (1), pp.4545. ⟨10.1038/s41467-018-06988-3⟩

Article dans une revue hal-02322485v1

Combination of a discovery LC-MS/MS analysis and a label-free quantification for the characterization of an epithelial-mesenchymal transition signature

Jordane Biarc , Philippe Gonzalo , Ivan Mikaelian , Laurent Fattet , Mathieu Deygas et al.

Journal of Proteomics, 2014, 110, pp.183-194. ⟨10.1016/j.jprot.2014.05.026⟩

Article dans une revue hal-01230272v1

Genetic and Pharmacologic Inhibition of mTORC1 Promotes EMT by a TGF-β-independent mechanism

Ivan Mikaelian , M. Malek , R. Gadet , J. Viallet , A. Garcia et al.

Cancer Research, 2013, 73 (22), pp.6621-6631. ⟨10.1158/0008-5472.CAN-13-0560⟩

Article dans une revue hal-01976686v1

Calcineurin A vs NS5A-TP2/HDDC2: a case study of site-directed low-frequency random mutagenesis for dissecting target specificity of peptide aptamers

Silvia Dibenedetto , David Cluet , Pierre-Nicolas Stebe , Véronique Baumlé , Jérémie Léault et al.

Molecular and Cellular Proteomics, 2013, 12 (7), pp.1939-52

Article dans une revue ensl-00960932v1

Tif1γ is essential for the terminal differentiation of mammary alveolar epithelial cells and for lactation through SMAD4 inhibition

Cédric Hesling , Jonathan Lopez , Laurent Fattet , Philippe Gonzalo , Isabelle Treilleux et al.

Development, 2013, 140 (1), pp.167--175. ⟨10.1242/dev.085068⟩

Article dans une revue hal-05005945v1

Down-regulation of BRCA1 expression by miR-146a and miR-146b-5p in triple negative sporadic breast cancers.

Amandine I Garcia , Monique Buisson , Pascale Bertrand , Ruth Rimokh , Etienne Rouleau et al.

EMBO Molecular Medicine, 2011, 3 (5), pp.279-90. ⟨10.1002/emmm.201100136⟩

Article dans une revue hal-00814005v1

Antagonistic regulation of EMT by TIF1γ and Smad4 in mammary epithelial cells.

Cédric Hesling , Laurent Fattet , Guillaume Teyre , Delphine Jury , Philippe Gonzalo et al.

EMBO Reports, 2011, 12 (7), pp.665-72. ⟨10.1038/embor.2011.78⟩

Article dans une revue hal-00835151v1
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A RasGAP SH3 peptide aptamer inhibits RasGAP-Aurora interaction and induces caspase-independent tumor cell death

Perayot Pamonsinlapatham , Réda Hadj-Slimane , Françoise Raynaud , Marc Bickle , Claudine Corneloup et al.

PLoS ONE, 2008, 3 (8), pp.e2902. ⟨10.1371/journal.pone.0002902⟩

Article dans une revue hal-00416049v1
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Interaction of the Epstein-Barr Virus mRNA Export Factor EB2 with Human Spen Proteins SHARP, OTT1, and a Novel Member of the Family, OTT3, Links Spen Proteins with Splicing Regulation and mRNA Export

Edwige Hiriart , Henri Gruffat , Monique Buisson , Ivan Mikaelian , Selina Keppler et al.

Journal of Biological Chemistry, 2005, 280 (44), pp.36935 - 36945. ⟨10.1074/jbc.m501725200⟩

Article dans une revue hal-01928098v1