JG

Jean-Charles Guéry

49
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Publications

Publications

Investigating Dysregulated X Chromosome Inactivation in Human B Cells and Plasmacytoid Dendritic Cells by RNA FISH

Berenice Faz-Lopez , Sophie Allart , Julie Chaumeil , Jean-Charles Guéry

Methods in Molecular Biology, 2026, Methods in Molecular Biology, 2990, pp.157-177. ⟨10.1007/978-1-0716-4997-8_13⟩

Article dans une revue hal-05498169v1
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Escape From X Chromosome Inactivation as a Driver of Plasmacytoid DC Heterogeneity in Health and Disease

Franck Barrat , Jean‐Charles Guéry

Immunological Reviews, In press, 336 (1), pp.e70074. ⟨10.1111/imr.70074⟩

Article dans une revue (article de synthèse) hal-05364668v1

Altered X-chromosome inactivation of the TLR7/8 locus and heterogeneity of pDCs in systemic sclerosis

Yong Du , Bérénice Faz-Lopez , Marie Dominique Ah Kioon , Claire Cenac , Michael Pierides et al.

Journal of Experimental Medicine, 2025, 222 (3), pp.e20231809. ⟨10.1084/jem.20231809⟩

Article dans une revue hal-02378928v1
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The Inactive X Chromosome: A Genetic Driver of Female‐Biased Rheumatic Autoimmune Disorders?

Léa Ferrayé , Mélissa Nieucel , Magali Savignac , Julie Chaumeil , Jean‐Charles Guéry et al.

European Journal of Immunology, 2025, 55 (5), pp.e202451331. ⟨10.1002/eji.202451331⟩

Article dans une revue hal-05148010v1
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In Asthmatic Patients, Sexual Dimorphism correlates With Androgen Receptor Expression in ILC2s at Single Cell‐Resolution

Nina Anesi , Mathilde Calmels , Laurent Guilleminault , Flora Abbas , Claire Cenac et al.

Clinical and Experimental Allergy, 2025, 55 (9), pp.851-853. ⟨10.1111/cea.70047⟩

Article dans une revue hal-05187200v1
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Altered X-chromosome inactivation predisposes to autoimmunity

Christophe Huret , Léa Ferrayé , Antoine David , Myriame Mohamed , Nicolas Valentin et al.

Science Advances , 2024, 10 (18), pp.eadn6537. ⟨10.1126/sciadv.adn6537⟩

Article dans une revue hal-04581817v1

Sexual dimorphism in skin immunity is mediated by an androgen-ILC2-dendritic cell axis

Liang Chi , Can Liu , Inta Gribonika , Julia Gschwend , Dan Corral et al.

Science, 2024, 384 (6692), pp.eadk6200. ⟨10.1126/science.adk6200⟩

Article dans une revue hal-04585729v1
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B cell‐intrinsic TLR7 signaling is required for neutralizing antibody responses to SARS‐CoV‐2 and pathogen‐like COVID‐19 vaccines

Charles-Henry Miquel , Flora Abbas , Claire Cénac , Charlotte Foret-Lucas , Chang Guo et al.

European Journal of Immunology, 2023, 53 (10), pp.e2350437. ⟨10.1002/eji.202350437⟩

Article dans une revue hal-04163592v2

PKCα interacts with Ca v 1.3 calcium channels to promote the Ca v 1.2/Ca v 1.3 duo tuning Th2 functions

Nicolas Giang , Thomas Villeneuve , Kilian Maire , José Enrique Mejia , Jean‐charles Guéry et al.

Allergy, 2023, 78 (3), pp.879-882. ⟨10.1111/all.15611⟩

Article dans une revue hal-04220236v1
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TLR8 escapes X chromosome inactivation in human monocytes and CD4+ T cells

Ali Youness , Claire Cenac , Berenice Faz-López , Solange Grunenwald , Franck J Barrat et al.

Biology of Sex Differences, 2023, 14 (1), pp.60. ⟨10.1186/s13293-023-00544-5⟩

Article dans une revue hal-04330722v1
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Influence of X chromosome in sex-biased autoimmune diseases

Charles-Henry Miquel , Berenice Faz-López , Jean‐charles Guéry

Journal of Autoimmunity, 2023, 137, pp.102992. ⟨10.1016/j.jaut.2023.102992⟩

Article dans une revue hal-04220151v1
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Targeting androgen signaling in ILC2s protects from IL-33–driven lung inflammation, independently of KLRG1

Eve Blanquart , Audrey Mandonnet , Marion Mars , Claire Cenac , Nina Anesi et al.

Journal of Allergy and Clinical Immunology, 2022, 149 (1), pp.237-251.e12. ⟨10.1016/j.jaci.2021.04.029⟩

Article dans une revue hal-03411390v1
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Female bonobos show social swelling by synchronizing their maximum swelling and increasing bonding

Elisa Demuru , Marta Caselli , Jean-Pascal Guéry , Carole Michelet , Franck Alexieff et al.

Scientific Reports, 2022, 12 (1), pp.17676. ⟨10.1038/s41598-022-22325-7⟩

Article dans une revue hal-04680578v1

Separation of the Ca V 1.2‐Ca V 1.3 calcium channel duo prevents type 2 allergic airway inflammation

Nicolas Giang , Marion Mars , Marc Moreau , Jose Mejia , Grégory Bouchaud et al.

Allergy, 2022, 77 (2), pp.525-539. ⟨10.1111/all.14993⟩

Article dans une revue hal-03344050v1
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HIV-1 infection enhances innate function and TLR7 expression in female plasmacytoid dendritic cells

Flora Abbas , Claire Cenac , Ali Youness , Pascal Azar , Pierre Delobel et al.

Life Science Alliance, 2022, 5 (10), pp.e202201452. ⟨10.26508/lsa.202201452⟩

Article dans une revue hal-04220272v1

Hydroxychloroquine inhibits proteolytic processing of endogenous TLR7 protein in human primary plasmacytoid dendritic cells

Claire Cenac , Mariette F. Ducatez , Jean‐Charles Guéry

European Journal of Immunology, 2022, 52, pp.54-61. ⟨10.1002/eji.202149361⟩

Article dans une revue hal-03651880v1
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Escape from X Chromosome Inactivation and the Female Predominance in Autoimmune Diseases

Ali Youness , Charles-Henry Miquel , Jean-Charles Guéry

International Journal of Molecular Sciences, 2021, 22 (3), pp.1114. ⟨10.3390/ijms22031114⟩

Article dans une revue hal-03652202v1
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Prédominance féminine des maladies auto-immunes

Charles-Henry Miquel , Ali Youness , Jean-Charles Guéry

Revue du Rhumatisme monographies, 2021, 88 (1), pp.3-7. ⟨10.1016/j.monrhu.2020.10.002⟩

Article dans une revue hal-03154504v1
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Sex Differences in Primary HIV Infection

Jean-Charles Guéry

Frontiers in Immunology, 2021, 12, pp.729233. ⟨10.3389/fimmu.2021.729233⟩

Article dans une revue hal-03651952v1
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Sex hormone regulation of innate lymphoid cells

Eve Blanquart , Sophie Laffont , Jean-Charles Guéry

Biomedical journal, 2020, 44 (2), pp.144-156. ⟨10.1016/j.bj.2020.11.007⟩

Article dans une revue hal-03153831v1
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TLR7 dosage polymorphism shapes interferogenesis and HIV-1 acute viremia in women

Pascal Azar , José E Mejía , Claire Cénac , Arnoo Shaiykova , Ali Youness et al.

JCI Insight, 2020, 5 (12), pp.e136047. ⟨10.1172/jci.insight.136047⟩

Article dans une revue pasteur-02864900v1

Asthma and allergy

Lucette Pelletier , Jean-Charles Guéry

Revue du Praticien (La), 2020, 70 (2), pp.195-199

Article dans une revue hal-03710120v1

Why Is Systemic Lupus Erythematosus More Common in Women?

Jean-Charles Guéry

Joint Bone Spine, 2019, 86 (3), pp.297-299. ⟨10.1016/j.jbspin.2018.12.004⟩

Article dans une revue hal-03568559v1

Female predisposition to TLR7-driven autoimmunity: gene dosage and the escape from X chromosome inactivation

Mélanie Souyris , José E Mejía , Julie Chaumeil , Jean-Charles Guéry

Seminars in Immunopathology, 2019, 41 (2), pp.153-164. ⟨10.1007/s00281-018-0712-y⟩

Article dans une revue hal-03568729v1

CD49d/CD29‐integrin controls the accumulation of plasmacytoid dendritic cells into the CNS during neuroinflammation

Arnaud Garnier , Sophie Laffont , Laure Garnier , Elisa Kaba , Urban Deutsch et al.

European Journal of Immunology, 2019, 49 (11), pp.2030-2043. ⟨10.1002/eji.201948086⟩

Article dans une revue hal-02372827v1

Estrogen Signaling in Bystander Foxp3 neg CD4 + T Cells Suppresses Cognate Th17 Differentiation in Trans and Protects from Central Nervous System Autoimmunity

Laure Garnier , Sophie Laffont , Karine Lélu , Nir Yogev , Ari Waisman et al.

Journal of Immunology, 2018, 201 (11), pp.3218-3228. ⟨10.4049/jimmunol.1800417⟩

Article dans une revue hal-02378915v1

TLR7 escapes X chromosome inactivation in immune cells

Mélanie Souyris , Claire Cenac , Pascal Azar , Danièle Daviaud , Astrid Canivet et al.

Science Immunology, 2018, 3 (19), ⟨10.1126/sciimmunol.aap8855⟩

Article dans une revue hal-03851873v1
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Androgen signaling negatively controls group 2 innate lymphoid cells

Sophie Laffont , Eve Blanquart , Magali Savignac , Claire Cénac , Gilles Laverny et al.

Journal of Experimental Medicine, 2017, 214 (6), pp.1581-1592. ⟨10.1084/jem.20161807⟩

Article dans une revue hal-03551225v1
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The β and α2δ auxiliary subunits of voltage-gated calcium channel 1 (Cav1) are required for Th2-lymphocyte function and acute allergic airway inflammation

Nicolas Rosa , Emily Triffaux , Virginie Robert , Marion Mars , Martin Klein et al.

Journal of Allergy and Clinical Immunology, 2017, Equipe III, 142 (3), pp.892 - +. ⟨10.1016/j.jaci.2017.09.045⟩

Article dans une revue hal-01828863v1
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Sex Differences in Plasmacytoid Dendritic Cell Levels of IRF5 Drive Higher IFN-α Production in Women.

Morgane Griesbeck , Susanne Ziegler , Sophie Laffont , Nikaïa Smith , Lise Chauveau et al.

Journal of Immunology, 2015, 195 (11), pp.5327-36. ⟨10.4049/jimmunol.1501684⟩

Article dans une revue pasteur-01372393v1

Estradiol promotes functional responses in inflammatory and steady-state dendritic cells through differential requirement for activation function-1 of estrogen receptor α.

Cyril Seillet , Nelly Rouquié , Eliane Foulon , Victorine Douin-Echinard , Andrée Krust et al.

Journal of Immunology, 2013, 190 (11), pp.5459-70. ⟨10.4049/jimmunol.1203312⟩

Article dans une revue inserm-00852281v1

The TLR-mediated response of plasmacytoid dendritic cells is positively regulated by estradiol in vivo through cell-intrinsic estrogen receptor α signaling.

Cyril Seillet , Sophie Laffont , Florence Trémollières , Nelly Rouquié , Claude Ribot et al.

Blood, 2012, 119 (2), pp.454-64. ⟨10.1182/blood-2011-08-371831⟩

Article dans une revue inserm-00726899v1

Estradiol administration controls eosinophilia through estrogen receptor-alpha activation during acute peritoneal inflammation.

Victorine Douin-Echinard , Bertrand Calippe , Audrey Billon-Galès , Coralie Fontaine , Françoise Lenfant et al.

Journal of Leukocyte Biology, 2011, 90 (1), pp.145-54. ⟨10.1189/jlb.0210073⟩

Article dans une revue inserm-00615500v1

Estrogen receptor α signaling in T lymphocytes is required for estradiol-mediated inhibition of Th1 and Th17 cell differentiation and protection against experimental autoimmune encephalomyelitis.

Karine Lélu , Sophie Laffont , Laurent Delpy , Pierre-Emmanuel Paulet , Therese Périnat et al.

Journal of Immunology, 2011, 187 (5), pp.2386-93. ⟨10.4049/jimmunol.1101578⟩

Article dans une revue hal-00697793v1

17Beta-estradiol promotes TLR4-triggered proinflammatory mediator production through direct estrogen receptor alpha signaling in macrophages in vivo.

Bertrand Calippe , Victorine Douin-Echinard , Laurent Delpy , Muriel Laffargue , Karine Lélu et al.

Journal of Immunology, 2010, 185 (2), pp.1169-76. ⟨10.4049/jimmunol.0902383⟩

Article dans une revue inserm-00504327v1

Endogenous estrogens, through estrogen receptor α, constrain autoimmune inflammation in female mice by limiting CD4+ T-cell homing into the CNS.

Karine Lélu , Laurent Delpy , Virginie Robert , Eliane Foulon , Sophie Laffont et al.

European Journal of Immunology, 2010, 40 (12), pp.3489-98. ⟨10.1002/eji.201040678⟩

Article dans une revue hal-00697795v1

Estrogen Receptor {alpha} Expression in Both Endothelium and Hematopoietic Cells Is Required for the Accelerative Effect of Estradiol on Reendothelialization.

Céline E. Toutain , Cédric Filipe , Audrey Billon , Coralie Fontaine , Laurent Brouchet et al.

Arteriosclerosis, Thrombosis, and Vascular Biology, 2009, epub ahead of print. ⟨10.1161/ATVBAHA.109.192849⟩

Article dans une revue inserm-00410359v1

Endothelial estrogen receptor-alpha plays a crucial role in the atheroprotective action of 17beta-estradiol in low-density lipoprotein receptor-deficient mice.

Audrey Billon-Galés , Coralie Fontaine , Victorine Douin-Echinard , Laurent Delpy , Hortense Berges et al.

Circulation, 2009, 120 (25), pp.2567-76. ⟨10.1161/CIRCULATIONAHA.109.898445⟩

Article dans une revue hal-00458859v1

Chronic estradiol administration in vivo promotes the proinflammatory response of macrophages to TLR4 activation: involvement of the phosphatidylinositol 3-kinase pathway.

Bertrand Calippe , Victorine Douin-Echinard , Muriel Laffargue , Henrik Laurell , Vanessa Rana-Poussine et al.

Journal of Immunology, 2008, 180 (12), pp.7980-8

Article dans une revue hal-00321739v1
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Estrogen receptor alpha, but not beta, is required for optimal dendritic cell differentiation and [corrected] CD40-induced cytokine production.

Victorine Douin-Echinard , Sophie Laffont , Cyril Seillet , Laurent Delpy , Andree Krust et al.

Journal of Immunology, 2008, 180 (6), pp.3661-9

Article dans une revue inserm-00312757v1
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Natural killer cells recruited into lymph nodes inhibit alloreactive T-cell activation through perforin-mediated killing of donor allogeneic dendritic cells.

Sophie Laffont , Cyril Seillet , John Ortaldo , Jérôme D. Coudert , Jean-Charles Guéry

Blood, 2008, 112 (3), pp.661-71. ⟨10.1182/blood-2007-10-120089⟩

Article dans une revue inserm-00306011v1

Role of inflammatory cytokines in the effect of estradiol on atheroma.

P. Gourdy , B. Calippe , H. Laurell , F. Trémollières , Victorine Douin-Echinard et al.

Clinical and Experimental Pharmacology and Physiology, 2008, 35 (4), pp.396-401. ⟨10.1111/j.1440-1681.2008.04885.x⟩

Article dans une revue hal-00323053v1

Understanding the controversy about hormonal replacement therapy: insights from estrogen effects on experimental and clinical atherosclerosis.

Jean-François Arnal , Victorine Douin-Echinard , Florence Tremollières , Anne-Dominique Terrisse , Pierre Sié et al.

Archives des Maladies du Coeur et des Vaisseaux, 2007, 100 (6-7), pp.554-62

Article dans une revue inserm-00423380v1

Calcium channel blocker prevents T helper type 2 cell-mediated airway inflammation.

Bruno Gomes , Marilena Djata Cabral , Alexandra Gallard , Magali Savignac , Pierre Paulet et al.

American Journal of Respiratory and Critical Care Medicine, 2007, 175 (11), pp.1117-24. ⟨10.1164/rccm.200607-1026OC⟩

Article dans une revue hal-00170629v1

The cGMP/protein kinase G pathway contributes to dihydropyridine-sensitive calcium response and cytokine production in TH2 lymphocytes.

Bruno Gomes , Magali Savignac , Marilena Djata Cabral , Pierre Paulet , Marc Moreau et al.

Journal of Biological Chemistry, 2006, 281 (18), pp.12421-7. ⟨10.1074/jbc.M510653200⟩

Article dans une revue hal-00170621v1

CD8+ T-cell-mediated killing of donor dendritic cells prevents alloreactive T helper type-2 responses in vivo.

Sophie Laffont , Jérôme D Coudert , Lucile Garidou , Laurent Delpy , Aurélie Wiedemann et al.

Blood, 2006, 108 (7), pp.2257-64. ⟨10.1182/blood-2005-10-4059⟩

Article dans une revue hal-00458864v1

Estrogen enhances susceptibility to experimental autoimmune myasthenia gravis by promoting type 1-polarized immune responses.

Laurent Delpy , Victorine Douin-Echinard , Lucile Garidou , Corinne Bruand , Abdelhadi Saoudi et al.

Journal of Immunology, 2005, 175 (8), pp.5050-7

Article dans une revue hal-00458865v1

The Influence of Sex Hormones and X Chromosome in Immune Responses

Nina Anesi , Charles-Henry Miquel , Sophie Laffont , Jean‐charles Guéry

Sabra L. Klein; Craig W. Roberts. Sex and Gender Differences in Infection and Treatments for Infectious Diseases, 441, Springer Cham, p. 21-59, 2023, Current Topics in Microbiology and Immunology, 978-3-031-35139-6. ⟨10.1007/978-3-031-35139-6_2⟩

Chapitre d'ouvrage hal-04220181v1

Deconstructing the sex bias in allergy and autoimmunity

Sophie Laffont , Jean-Charles Guéry

Advances in Immunology, 142 (chap 2), Elsevier, pp.35-64, 2019, ⟨10.1016/bs.ai.2019.04.001⟩

Chapitre d'ouvrage hal-02378906v1