jean christophe delpech

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Publications

Sex specific correction of maternal inflammation-induced behavioral abnormalities by the inhibition of colony-stimulating factor 1 receptor

Jean-Christophe Delpech , Hana Yeh , Srinidhi Venkatesan Kalavai , Yang You , Zhi Ruan et al.

Brain, Behavior, and Immunity, 2026, 131, pp.106163. ⟨10.1016/j.bbi.2025.106163⟩

Article dans une revue hal-05546988v1
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Rodent models of Alzheimer's disease: Critical analysis of current hypotheses and pathways for future research

Pasindu Hansana Singhaarachchi , Peter Antal , Frédéric Calon , Carsten Culmsee , Jean-Christophe Delpech et al.

Progress in Neurobiology, 2025, 252, pp.102821. ⟨10.1016/j.pneurobio.2025.102821⟩

Article dans une revue hal-05273054v1

Efficient enrichment of plasma-derived extracellular vesicles from small volumes of bovine blood

Vincent Prieur , Isabelle Cassar-Malek , Arnaud Delavaud , Liam Barry-Carroll , Jean-Christophe Delpech et al.

Journal of Animal Science, 2025, 103, pp.skaf354. ⟨10.1093/jas/skaf354⟩

Article dans une revue hal-05448255v1

GLP-1-mediated targeting of inflammation corrects obesogenic memory in male mice

Stéphane Léon , Julie Benoit , Samantha Clark , Philippe Zizzari , Bin Yang et al.

Diabetes, 2025, ⟨10.2337/db24-1071⟩

Article dans une revue hal-05191590v1

Microglial GPR56 is the molecular target of maternal immune activation-induced parvalbumin-positive interneuron deficits

Diankun Yu , Tao Li , Jean-Christophe Delpech , Beika Zhu , Priya Kishore et al.

Science Advances , 2022, 8 (18), ⟨10.1126/sciadv.abm2545⟩

Article dans une revue hal-04115237v1

Correction to: Plaque associated microglia hyper-secrete extracellular vesicles and accelerate tau propagation in a humanized APP mouse model

Kevin Clayton , Jean-Christophe Delpech , Shawn Herron , Naotoshi Iwahara , Maria Ericsson et al.

Molecular Neurodegeneration, 2021, 16 (1), ⟨10.1186/s13024-021-00447-2⟩

Article dans une revue hal-03259490v1
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Wine yeast species show strong inter- and intra-specific variability in their sensitivity to ultraviolet radiation

Jean-Christophe Delpech , Dhruba Pathak , Merina Varghese , Srinidhi Venkatesan Kalavai , Emma C. Hays et al.

Food Microbiology, 2021, 100 (611), ⟨10.1016/j.fm.2021.103864⟩

Article dans une revue hal-03385929v1
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Plaque associated microglia hyper-secrete extracellular vesicles and accelerate tau propagation in a humanized APP mouse model

Kevin Clayton , Jean-Christophe Delpech , Shawn Herron , Naotoshi Iwahara , Maria Ericsson et al.

Molecular Neurodegeneration, 2021, 16, pp.18. ⟨10.1186/s13024-021-00440-9⟩

Article dans une revue hal-03259493v1

Inhibition of colony stimulating factor 1 receptor corrects maternal inflammation-induced microglial and synaptic dysfunction and behavioral abnormalities

Seiko Ikezu , Hana Yeh , Jean-Christophe Delpech , Maya Woodbury , Alicia van Enoo et al.

Molecular Psychiatry, 2020, ⟨10.1038/s41380-020-0671-2⟩

Article dans une revue hal-03259500v1

P2RX7 inhibitor suppresses exosome secretion and disease phenotype in P301S tau transgenic mice

Zhi Ruan , Jean-Christophe Delpech , Srinidhi Venkatesan Kalavai , Alicia van Enoo , Jianqiao Hu et al.

Molecular Neurodegeneration, 2020, 15 (1), ⟨10.1186/s13024-020-00396-2⟩

Article dans une revue hal-03259497v1

Cre-inducible Adeno Associated Virus-mediated Expression of P301L Mutant Tau Causes Motor Deficits and Neuronal Degeneration in the Substantia Nigra

Yang You , Mina Botros , Alicia Enoo , Aaron Bockmiller , Shawn Herron et al.

Neuroscience, 2019, 422, pp.65-74. ⟨10.1016/j.neuroscience.2019.10.001⟩

Article dans une revue hal-03259501v1

Neuroimmune Crosstalk through Extracellular Vesicles in Health and Disease

Jean-Christophe Delpech , Shawn Herron , Mina Botros , Tsuneya Ikezu

Trends in Neurosciences, 2019, 42 (5), pp.361-372. ⟨10.1016/j.tins.2019.02.007⟩

Article dans une revue hal-03259504v1
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Dietary n-3 long chain PUFA supplementation promotes a pro-resolving oxylipin profile in the brain

Charlotte Rey , Jean-Christophe Delpech , Charlotte Madore , Agnès Nadjar , Andrew D. Greenhalgh et al.

Brain, Behavior, and Immunity, 2019, 76, pp.17-27. ⟨10.1016/j.bbi.2018.07.025⟩

Article dans une revue hal-02627173v1

Blood biomarkers for evaluation of perinatal encephalopathy

Jean-Christophe Delpech , Ernest Graham , Allen Everett , Frances Northington

Current Opinion in Pediatrics, 2018, 30 (2), pp.199-203. ⟨10.1097/MOP.0000000000000591⟩

Article dans une revue hal-03259511v1

Amygdala hyper-connectivity in a mouse model of unpredictable early life stress

Jean-Christophe Delpech , Frances Johnson , Garth Thompson , Lan Wei , Jin Hao et al.

Translational Psychiatry, 2018, 8 (1), ⟨10.1038/s41398-018-0092-z⟩

Article dans une revue hal-03259513v1

Circulating bacterial lipopolysaccharide-induced inflammation reduces flow in brain-irrigating arteries independently from cerebrovascular prostaglandin production

Frédéric Villéga , Jean-Christophe Delpech , Marion Griton , Caroline André , Jean-Michel Franconi et al.

Neuroscience, 2017, 346, pp.160-172. ⟨10.1016/j.neuroscience.2017.01.018⟩

Article dans une revue hal-03259516v1

Dynamic cross-talk between microglia and peripheral monocytes underlies stress-induced neuroinflammation and behavioral consequences

Jean-Christophe Delpech , Eric Wohleb

Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2017, 79, pp.40-48. ⟨10.1016/j.pnpbp.2016.04.013⟩

Article dans une revue hal-03259525v1
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Circulating bacterial lipopolysaccharide-induced inflammation reduces flow in brain-irrigating arteries independently from cerebrovascular prostaglandin production

Frédéric Villéga , Jean-Christophe Delpech , Marion Griton , Caroline André , Sylvain Miraux et al.

Neuroscience, 2017, 346, pp.160-172. ⟨10.1016/j.neuroscience.2017.01.018⟩

Article dans une revue hal-02376362v1

Early life stress perturbs the maturation of microglia in the developing hippocampus

Jean-Christophe Delpech , Lan Wei , Jin Hao , Xiaoqing Yu , Charlotte Madore et al.

Brain, Behavior, and Immunity, 2016, 57, pp.79-93. ⟨10.1016/j.bbi.2016.06.006⟩

Article dans une revue hal-03259519v1

Microglial Activation Enhances Associative Taste Memory through Purinergic Modulation of Glutamatergic Neurotransmission

Jean-Christophe Delpech , N. Saucisse , S. Parkes , C. Lacabanne , Agnès Aubert et al.

Journal of Neuroscience, 2015, 35 (7), pp.3022-3033. ⟨10.1523/JNEUROSCI.3028-14.2015⟩

Article dans une revue hal-03259535v1

Dietary n-3 PUFAs Deficiency Increases Vulnerability to Inflammation-Induced Spatial Memory Impairment

Jean-Christophe Delpech , Aurore Thomazeau , Charlotte Madore , Clémentine Bosch-Bouju , Thomas Larrieu et al.

Neuropsychopharmacology, 2015, 40 (12), pp.2774-2787. ⟨10.1038/npp.2015.127⟩

Article dans une revue hal-03259529v1

Microglia in neuronal plasticity: influence of stress

Jean-Christophe Delpech , Charlotte Madore , Agnes Nadjar , Corinne Joffre , Eric S. Wohleb et al.

Neuropharmacology, 2015, 96 (Part A), pp.19-28. ⟨10.1016/j.neuropharm.2014.12.034⟩

Article dans une revue hal-02636176v1

Transgenic increase in n-3/n-6 fatty acid ratio protects against cognitive deficits induced by an immune challenge through decrease of neuroinflammation

Jean-Christophe Delpech , Charlotte Madore , Corinne Joffre , Agnès Aubert , Jing Xuan Kang et al.

Neuropsychopharmacology, 2015, 40 (3), pp.525-536. ⟨10.1038/npp.2014.196⟩

Article dans une revue hal-02635645v1

N-3 polyunsaturated fatty acid and neuroinflammation in aging and Alzheimer’s disease

Sophie Layé , Charlotte Madore , Isabelle St-Amour , Jean-Christophe Delpech , Corinne Joffre et al.

Nutrition and Aging, 2015, 3 (1), pp.33-47. ⟨10.3233/NUA-150049⟩

Article dans une revue hal-02630551v1

Dietary n-3 PUFAs deficiency increases vulnerability to inflammation-induced spatial memory impairment

Jean-Christophe Delpech , Aurore Thomazeau , Charlotte Madore , Clémentine Bosch-Bouju , Thomas Larrieu et al.

Neuropsychopharmacology, 2015, 40 (12), pp.2774-2787. ⟨10.1038/npp.2015.127⟩

Article dans une revue hal-02640350v1

Transgenic Increase in n-3/n-6 Fatty Acid Ratio Protects Against Cognitive Deficits Induced by an Immune Challenge through Decrease of Neuroinflammation

Jean-Christophe Delpech , Charlotte Madore , Corinne Joffre , Agnès Aubert , Jing Xuan Kang et al.

Neuropsychopharmacology, 2015, 40 (3), pp.525-536. ⟨10.1038/npp.2014.196⟩

Article dans une revue hal-03259541v1

Nutritional n-3 PUFAs deficiency during perinatal periods alters brain innate immune system and neuronal plasticity-associated genes

Charlotte Madore , Agnès Nadjar , Jean-Christophe Delpech , A. Sere , A. Aubert et al.

Brain, Behavior, and Immunity, 2014, 41, pp.22-31. ⟨10.1016/j.bbi.2014.03.021⟩

Article dans une revue istex hal-03259544v1
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Mechanisms involved in dual vasopressin/apelin neuron dysfunction during aging

J. Sauvant , Jean-Christophe Delpech , K. Palin , N. de Mota , J. Dudit et al.

PLoS ONE, 2014, 9 (2), pp.e87421. ⟨10.1371/journal.pone.0087421⟩

Article dans une revue hal-01369526v1

Nutritional n-3 PUFAs deficiency during perinatal periods alters brain innate immune system and neuronal plasticity-associated genes

Charlotte Madore , Agnes Nadjar , Jean-Christophe Delpech , Alexandra Séré , Agnès Aubert et al.

Brain, Behavior, and Immunity, 2014, 41, pp.22-31. ⟨10.1016/j.bbi.2014.03.021⟩

Article dans une revue istex hal-02640850v1

Early morphofunctional plasticity of microglia in response to acute lipopolysaccharide

Charlotte Madore , Corinne Joffre , Jean-Christophe Delpech , Veronique de Smedt-Peyrusse , Agnès Aubert et al.

Brain, Behavior, and Immunity, 2013, 34, pp.151-158. ⟨10.1016/j.bbi.2013.08.008⟩

Article dans une revue istex hal-02646632v1

Early morphofunctional plasticity of microglia in response to acute lipopolysaccharide

C. Madore , C. Joffre , Jean-Christophe Delpech , V. de Smedt-Peyrusse , A. Aubert et al.

Brain, Behavior, and Immunity, 2013, 34, pp.151-158. ⟨10.1016/j.bbi.2013.08.008⟩

Article dans une revue istex hal-03259548v1

Long term adequate n-3 polyunsaturated fatty acid diet protects from depressive-like behavior but not from working memory disruption and brain cytokine expression in aged mice

Jean-Christophe Delpech , Aurélie Moranis , Véronique de Smedt-Peyrusse , Agnès Aubert , Philippe Guesnet et al.

Brain, Behavior, and Immunity, 2012, 26 (5), pp.721-731. ⟨10.1016/j.bbi.2011.11.001⟩

Article dans une revue istex hal-03259550v1

Long term adequate n-3 polyunsaturated fatty acid diet protects from depressive-like behavior but not from working memory disruption and brain cytokine expression in aged mice

Aurélie Moranis , Jean-Christophe Delpech , Veronique de Smedt-Peyrusse , Agnès Aubert , Philippe P. Guesnet et al.

Brain, Behavior, and Immunity, 2012, 26 (5), pp.721-731. ⟨10.1016/j.bbi.2011.11.001⟩

Article dans une revue istex hal-02647840v1

Neuroinflammation and aging: influence of dietary n-3 polyunsaturated fatty acid

Sophie Layé , Jean-Christophe Delpech , Veronique de Smedt-Peyrusse , Corinne Joffre , Thomas Larrieu et al.

Oléagineux, Corps Gras, Lipides, 2011, 18 (6), pp.301 - 306. ⟨10.1051/ocl.2011.0412⟩

Article dans une revue hal-02643433v1

Phénotypage multidimensionnel : intérêt de l’outil HDeeP

Cécile Gladine , Nils Paulhe , Estelle Pujos-Guillot , Claire Sulmont-Rossé , Sophie Layé et al.

6èmes Assises régionales de Nutrition Santé, Oct 2024, Grenoble, France

Communication dans un congrès hal-04817167v1

Dietary lipids and microglia priming

Sophie Layé , Charlotte Madore , Jean-Christophe Delpech , Agnes Nadjar , Corinne Joffre

11. European Meeting on Glial Cell Function in Health and Disease, Jul 2013, Berlin, Germany. ⟨10.1002/glia.22531⟩

Communication dans un congrès istex hal-02747574v1

Impact de l’inflammation centrale sur la mémoire

Jean-Christophe Delpech

Sciences du Vivant [q-bio]. Université de Bordeaux Ségalen (Bordeaux 2), 2012. Français. ⟨NNT : ⟩

Thèse tel-02809292v1