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jean christophe delpech

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Wolframin-1-expressing neurons in the entorhinal cortex propagate tau to CA1 neurons and impair hippocampal memory in mice

Jean-Christophe Delpech , Dhruba Pathak , Merina Varghese , Srinidhi Venkatesan Kalavai , Emma C. Hays et al.
Science Translational Medicine, 2021, 13 (611), ⟨10.1126/scitranslmed.abe8455⟩
Journal articles hal-03385929v1

Correction to: Plaque associated microglia hyper-secrete extracellular vesicles and accelerate tau propagation in a humanized APP mouse model

Kevin Clayton , Jean-Christophe Delpech , Shawn Herron , Naotoshi Iwahara , Maria Ericsson et al.
Molecular Neurodegeneration, 2021, 16 (1), ⟨10.1186/s13024-021-00447-2⟩
Journal articles hal-03259490v1
Image document

Plaque associated microglia hyper-secrete extracellular vesicles and accelerate tau propagation in a humanized APP mouse model

Kevin Clayton , Jean-Christophe Delpech , Shawn Herron , Naotoshi Iwahara , Maria Ericsson et al.
Molecular Neurodegeneration, 2021, 16, pp.18. ⟨10.1186/s13024-021-00440-9⟩
Journal articles hal-03259493v1

Inhibition of colony stimulating factor 1 receptor corrects maternal inflammation-induced microglial and synaptic dysfunction and behavioral abnormalities

Seiko Ikezu , Hana Yeh , Jean-Christophe Delpech , Maya Woodbury , Alicia van Enoo et al.
Molecular Psychiatry, 2020, ⟨10.1038/s41380-020-0671-2⟩
Journal articles hal-03259500v1

P2RX7 inhibitor suppresses exosome secretion and disease phenotype in P301S tau transgenic mice

Zhi Ruan , Jean-Christophe Delpech , Srinidhi Venkatesan Kalavai , Alicia van Enoo , Jianqiao Hu et al.
Molecular Neurodegeneration, 2020, 15 (1), ⟨10.1186/s13024-020-00396-2⟩
Journal articles hal-03259497v1

Cre-inducible Adeno Associated Virus-mediated Expression of P301L Mutant Tau Causes Motor Deficits and Neuronal Degeneration in the Substantia Nigra

Yang You , Mina Botros , Alicia Enoo , Aaron Bockmiller , Shawn Herron et al.
Neuroscience, 2019, 422, pp.65-74. ⟨10.1016/j.neuroscience.2019.10.001⟩
Journal articles hal-03259501v1

Neuroimmune Crosstalk through Extracellular Vesicles in Health and Disease

Jean-Christophe Delpech , Shawn Herron , Mina Botros , Tsuneya Ikezu
Trends in Neurosciences, 2019, 42 (5), pp.361-372. ⟨10.1016/j.tins.2019.02.007⟩
Journal articles hal-03259504v1
Image document

Dietary n-3 long chain PUFA supplementation promotes a pro-resolving oxylipin profile in the brain

Charlotte Rey , Jean-Christophe Delpech , Charlotte Madore , Agnès Nadjar , Andrew D. Greenhalgh et al.
Brain, Behavior, and Immunity, 2019, 76, pp.17-27. ⟨10.1016/j.bbi.2018.07.025⟩
Journal articles hal-02627173v1

Amygdala hyper-connectivity in a mouse model of unpredictable early life stress

Jean-Christophe Delpech , Frances Johnson , Garth Thompson , Lan Wei , Jin Hao et al.
Translational Psychiatry, 2018, 8 (1), ⟨10.1038/s41398-018-0092-z⟩
Journal articles hal-03259513v1

Blood biomarkers for evaluation of perinatal encephalopathy

Jean-Christophe Delpech , Ernest Graham , Allen Everett , Frances Northington
Current Opinion in Pediatrics, 2018, 30 (2), pp.199-203. ⟨10.1097/MOP.0000000000000591⟩
Journal articles hal-03259511v1

Circulating bacterial lipopolysaccharide-induced inflammation reduces flow in brain-irrigating arteries independently from cerebrovascular prostaglandin production

Frédéric Villéga , Jean-Christophe Delpech , Marion Griton , Caroline André , Jean-Michel Franconi et al.
Neuroscience, 2017, 346, pp.160-172. ⟨10.1016/j.neuroscience.2017.01.018⟩
Journal articles hal-03259516v1
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Circulating bacterial lipopolysaccharide-induced inflammation reduces flow in brain-irrigating arteries independently from cerebrovascular prostaglandin production

Frédéric Villéga , Jean-Christophe Delpech , Marion Griton , Caroline André , Sylvain Miraux et al.
Neuroscience, 2017, 346, pp.160-172. ⟨10.1016/j.neuroscience.2017.01.018⟩
Journal articles hal-02376362v1

Dynamic cross-talk between microglia and peripheral monocytes underlies stress-induced neuroinflammation and behavioral consequences

Jean-Christophe Delpech , Eric Wohleb
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2017, 79, pp.40-48. ⟨10.1016/j.pnpbp.2016.04.013⟩
Journal articles hal-03259525v1

Early life stress perturbs the maturation of microglia in the developing hippocampus

Jean-Christophe Delpech , Lan Wei , Jin Hao , Xiaoqing Yu , Charlotte Madore et al.
Brain, Behavior, and Immunity, 2016, 57, pp.79-93. ⟨10.1016/j.bbi.2016.06.006⟩
Journal articles hal-03259519v1

Microglial Activation Enhances Associative Taste Memory through Purinergic Modulation of Glutamatergic Neurotransmission

Jean-Christophe Delpech , N. Saucisse , S. Parkes , C. Lacabanne , Agnès Aubert et al.
Journal of Neuroscience, 2015, 35 (7), pp.3022-3033. ⟨10.1523/JNEUROSCI.3028-14.2015⟩
Journal articles hal-03259535v1

Microglial Activation Enhances Associative Taste Memory through Purinergic Modulation of Glutamatergic Neurotransmission

Jean-Christophe Delpech , N. Saucisse , S. Parkes , C. Lacabanne , A. Aubert et al.
Journal of Neuroscience, 2015, 35 (7), pp.3022-3033. ⟨10.1523/JNEUROSCI.3028-14.2015⟩
Journal articles hal-02347951v1

Transgenic increase in n-3/n-6 fatty acid ratio protects against cognitive deficits induced by an immune challenge through decrease of neuroinflammation

Jean-Christophe Delpech , Charlotte Madore , Corinne Joffre , Agnès Aubert , Jing Xuan Kang et al.
Neuropsychopharmacology, 2015, 40 (3), pp.525-536. ⟨10.1038/npp.2014.196⟩
Journal articles hal-02635645v1

Microglia in neuronal plasticity: Influence of stress

Jean-Christophe Delpech , Charlotte Madore , Agnes Nadjar , Corinne Joffre , Eric Wohleb et al.
Neuropharmacology, 2015, 96, pp.19-28. ⟨10.1016/j.neuropharm.2014.12.034⟩
Journal articles hal-03259538v1

Dietary n-3 PUFAs deficiency increases vulnerability to inflammation-induced spatial memory impairment

Jean-Christophe Delpech , Aurore Thomazeau , Charlotte Madore , Clémentine Bosch-Bouju , Thomas Larrieu et al.
Neuropsychopharmacology, 2015, 40 (12), pp.2774-2787. ⟨10.1038/npp.2015.127⟩
Journal articles hal-02640350v1

N-3 polyunsaturated fatty acid and neuroinflammation in aging and Alzheimer’s disease

Sophie Layé , Charlotte Madore , Isabelle St-Amour , Jean-Christophe Delpech , Corinne Joffre et al.
Nutrition and Aging, 2015, 3 (1), pp.33-47. ⟨10.3233/NUA-150049⟩
Journal articles hal-02630551v1

Transgenic Increase in n-3/n-6 Fatty Acid Ratio Protects Against Cognitive Deficits Induced by an Immune Challenge through Decrease of Neuroinflammation

Jean-Christophe Delpech , Charlotte Madore , Corinne Joffre , Agnès Aubert , Jing Xuan Kang et al.
Neuropsychopharmacology, 2015, 40 (3), pp.525-536. ⟨10.1038/npp.2014.196⟩
Journal articles hal-03259541v1

Dietary n-3 PUFAs Deficiency Increases Vulnerability to Inflammation-Induced Spatial Memory Impairment

Jean-Christophe Delpech , Aurore Thomazeau , Charlotte Madore , Clémentine Bosch-Bouju , Thomas Larrieu et al.
Neuropsychopharmacology, 2015, 40 (12), pp.2774-2787. ⟨10.1038/npp.2015.127⟩
Journal articles hal-03259529v1

Microglia in neuronal plasticity: influence of stress

Jean-Christophe Delpech , Charlotte Madore , Agnes Nadjar , Corinne Joffre , Eric S. Wohleb et al.
Neuropharmacology, 2015, 96 (Part A), pp.19-28. ⟨10.1016/j.neuropharm.2014.12.034⟩
Journal articles hal-02636176v1

Nutritional n-3 PUFAs deficiency during perinatal periods alters brain innate immune system and neuronal plasticity-associated genes

Charlotte Madore , Agnès Nadjar , Jean-Christophe Delpech , A. Sere , A. Aubert et al.
Brain, Behavior, and Immunity, 2014, 41, pp.22-31. ⟨10.1016/j.bbi.2014.03.021⟩
Journal articles hal-03259544v1

Nutritional n-3 PUFAs deficiency during perinatal periods alters brain innate immune system and neuronal plasticity-associated genes

Charlotte Madore , Agnes Nadjar , Jean-Christophe Delpech , Alexandra Séré , Agnès Aubert et al.
Brain, Behavior, and Immunity, 2014, 41, pp.22-31. ⟨10.1016/j.bbi.2014.03.021⟩
Journal articles hal-02640850v1
Image document

Mechanisms involved in dual vasopressin/apelin neuron dysfunction during aging

J. Sauvant , Jean-Christophe Delpech , K. Palin , N. de Mota , J. Dudit et al.
PLoS ONE, 2014, 9 (2), pp.e87421. ⟨10.1371/journal.pone.0087421⟩
Journal articles hal-01369526v1

Early morphofunctional plasticity of microglia in response to acute lipopolysaccharide

Charlotte Madore , Corinne Joffre , Jean-Christophe Delpech , Veronique de Smedt-Peyrusse , Agnès Aubert et al.
Brain, Behavior, and Immunity, 2013, 34, pp.151-158. ⟨10.1016/j.bbi.2013.08.008⟩
Journal articles hal-02646632v1

Early morphofunctional plasticity of microglia in response to acute lipopolysaccharide

C. Madore , C. Joffre , Jean-Christophe Delpech , V. de Smedt-Peyrusse , A. Aubert et al.
Brain, Behavior, and Immunity, 2013, 34, pp.151-158. ⟨10.1016/j.bbi.2013.08.008⟩
Journal articles hal-03259548v1

Long term adequate n-3 polyunsaturated fatty acid diet protects from depressive-like behavior but not from working memory disruption and brain cytokine expression in aged mice

Jean-Christophe Delpech , Aurélie Moranis , Véronique de Smedt-Peyrusse , Agnès Aubert , Philippe Guesnet et al.
Brain, Behavior, and Immunity, 2012, 26 (5), pp.721-731. ⟨10.1016/j.bbi.2011.11.001⟩
Journal articles hal-03259550v1

Long term adequate n-3 polyunsaturated fatty acid diet protects from depressive-like behavior but not from working memory disruption and brain cytokine expression in aged mice

Aurélie Moranis , Jean-Christophe Delpech , Veronique de Smedt-Peyrusse , Agnès Aubert , Philippe P. Guesnet et al.
Brain, Behavior, and Immunity, 2012, 26 (5), pp.721-731. ⟨10.1016/j.bbi.2011.11.001⟩
Journal articles hal-02647840v1

Neuroinflammation and aging: influence of dietary n-3 polyunsaturated fatty acid

Sophie Layé , Jean-Christophe Delpech , Veronique de Smedt-Peyrusse , Corinne Joffre , Thomas Larrieu et al.
Oléagineux, Corps Gras, Lipides, 2011, 18 (6), pp.301 - 306. ⟨10.1051/ocl.2011.0412⟩
Journal articles hal-02643433v1

Dietary lipids and microglia priming

Sophie Layé , Charlotte Madore , Jean-Christophe Delpech , Agnes Nadjar , Corinne Joffre et al.
11. European Meeting on Glial Cell Function in Health and Disease, Jul 2013, Berlin, Germany. ⟨10.1002/glia.22531⟩
Conference papers hal-02747574v1

Impact de l’inflammation centrale sur la mémoire

Jean-Christophe Delpech
Sciences du Vivant [q-bio]. Université de Bordeaux Ségalen (Bordeaux 2), 2012. Français. ⟨NNT : ⟩
Theses tel-02809292v1