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Jean-Louis Milan

29
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Researcher identifiers

Presentation

I have begun developing computational modelling of cytoskeleton dynamics to understand how the cells adapt their structure to their environment. I have succeed in proposing mechanisms of cell adhesion and cell migration guided by substrate shape. Based on these results of our models that reproduced observed phenomenon on static cellular environment, I have built the idea of upgrading the models into avatars of cell to develop strategies for tissue engineering based on in silico live predicting tool that a are able to guide cell functions into dynamic cellular environments.

Publications

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The effect of index finger distal interphalangeal joint arthrodesis on muscle forces and adjacent joint contact pressures

Thomas Valerio , Benjamin Goislard de Monsabert , Barthélémy Faudot , Jean-Bapstiste De Villeneuve de Bargemon , Charlotte Jaloux et al.
Medical and Biological Engineering and Computing, 2022
Journal articles hal-03854600v1
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Mechanobiological model to study the influence of screw design and surface treatment on osseointegration

Nicolas Rousseau , Patrick Chabrand , Arnaud Destainville , Olivier Richart , Jean-Louis Milan et al.
Computer Methods in Biomechanics and Biomedical Engineering, 2021, pp.1-17. ⟨10.1080/10255842.2021.1950144⟩
Journal articles hal-03467261v1
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Local tissue effects and peri‐implant bone healing induced by implant surface treatment: an in vivo study in the sheep

Nicolas Rousseau , Ines Msolli , Patrick Chabrand , Arnaud Destainville , Olivier Richart et al.
Journal of Periodontal Research, 2021, ⟨10.1111/jre.12878⟩
Journal articles hal-03192648v1
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Mechanical performance comparison of two surgical constructs for wrist four-corner arthrodesis via dorsal and radial approaches

Barthélémy Faudot , Julien Ballerini , Mark Ross , Philippe Bellemère , Benjamin Goislard de Monsabert et al.
Clinical Biomechanics, 2021, 82, pp.105274. ⟨10.1016/j.clinbiomech.2021.105274⟩
Journal articles hal-03195609v1
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Mechanical performance comparison of two surgical constructs for wrist four-corner arthrodesis via dorsal and radial approaches

Barthélémy Faudot , Julien Ballerini , Mark Ross , Philippe Bellemère , Benjamin Goislard de Monsabert et al.
Clinical Biomechanics, 2021, 82 (15), pp.105274. ⟨10.1016/j.clinbiomech.2021.105274⟩
Journal articles hal-03192595v1
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Estimation of joint contact pressure in the index finger using a hybrid finite element musculoskeletal approach

Barthélémy Faudot , Jean-Louis Milan , Benjamin Goislard de Monsabert , Thomas Le Corroller , Laurent Vigouroux et al.
Computer Methods in Biomechanics and Biomedical Engineering, 2020, pp.1-11. ⟨10.1080/10255842.2020.1793965⟩
Journal articles hal-02905574v1
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Application of the Johnson-Cook plasticity model in the Finite Element simulations of the nanoindentation of the cortical bone

Djamel Remache , Marie Semaan , Jean-Marie Rossi , Martine Pithioux , Jean-Louis Milan et al.
Journal of the mechanical behavior of biomedical materials, 2020, 101, pp.103426. ⟨10.1016/j.jmbbm.2019.103426⟩
Journal articles hal-02282870v1
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Estimation of joint contact pressure in the index finger using a hybrid finite element musculoskeletal approach

Barthélémy Faudot , Jean-Louis Milan , Benjamin Goislard de Monsabert , Thomas Le Corroller , Laurent Vigouroux et al.
Computer Methods in Biomechanics and Biomedical Engineering, 2020, 23 (15), pp.1225-1235. ⟨10.1080/10255842.2020.1793965⟩
Journal articles hal-03192663v1

Simulating pharmaceutical treatment effects on osteoporosis via a bone remodeling algorithm targeting hypermineralized sites

Jean-Marie Rossi , Milan Jean-Louis , Chan Yone Claudia , Rossi Jean-Marie , Chabrand Patrick et al.
Medical Engineering & Physics, 2020, 76, pp.56-68. ⟨10.1016/j.medengphy.2019.10.011⟩
Journal articles hal-03550961v1
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Simulating pharmaceutical treatment effects on osteoporosis via a bone remodeling algorithm targeting hypermineralized sites

Jean-Louis Milan , Chan Yone Claudia , Rossi Jean-Marie , Chabrand Patrick
Medical Engineering & Physics, 2020, 76, pp.56 - 68. ⟨10.1016/j.medengphy.2019.10.011⟩
Journal articles hal-03481370v1
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Actomyosin, vimentin and LINC complex pull on osteosarcoma nuclei to deform on micropillar topography

Nayana Tusamda Wakhloo , Sebastian Anders , Florent Badique , Melanie Eichhorn , Isabelle Brigaud et al.
Biomaterials, 2020, 234, pp.119746. ⟨10.1016/j.biomaterials.2019.119746⟩
Journal articles hal-02525268v1
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Investigating endodontic sealers eugenol and hydrocortisone roles in modulating the initial steps of inflammation

Charlotte Jeanneau , Thomas Giraud , Jean-Louis Milan , Imad About
Clinical Oral Investigations, 2019, 24 (2), pp.639-647. ⟨10.1007/s00784-019-02957-2⟩
Journal articles hal-02529087v1
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The consequence of substrates of large- scale rigidity on actin network tension in adherent cells

Ian Manifacier , Kevin M Beussman , Sangyoon J Han , Nathan J Sniadecki , Imad About et al.
Computer Methods in Biomechanics and Biomedical Engineering, 2019, 22 (13), pp.1073-1082. ⟨10.1080/10255842.2019.1629428⟩
Journal articles hal-02283812v1
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A biophysical model for curvature-guided cell migration

Maxime Vassaux , Laurent Pieuchot , Karine Anselme , Maxence Bigerelle , Jean-Louis Milan et al.
Biophysical Journal, 2019, 117 (6), pp.1136-1144. ⟨10.1016/j.bpj.2019.07.022⟩
Journal articles hal-02284526v1
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Curvotaxis directs cell migration through cell-scale curvature landscapes

Laurent Pieuchot , Julie Marteau , Alain Guignandon , Thomas dos Santos , Isabelle Brigaud et al.
Nature Communications, 2018, 9, ⟨10.1038/s41467-018-06494-6⟩
Journal articles hal-01960533v1

Topology Topology optimization and additive manufacturing: Comparison of conception methods using industrial codes

Yassine Saadlaoui , Jean-Louis Milan , Jean-Marie Rossi , Patrick Chabrand
Journal of Manufacturing Systems, 2017, 43 (1), pp.178-186. ⟨10.1016/j.jmsy.2017.03.006⟩
Journal articles hal-01691151v1
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Computational Tension Mapping of Adherent Cells Based on Actin Imaging

Ian Manifacier , Jean-Louis Milan , Charlotte Jeanneau , Fanny Chmilewsky , Patrick Chabrand et al.
PLoS ONE, 2016, 11 (1), ⟨10.1371/journal.pone.0146863⟩
Journal articles hal-01443844v1

In silico CDM model sheds light on force transmission in cell from focal adhesions to nucleus

Jean-Louis Milan , Ian Manifacier , Kevin M. Beussman , Sangyoon J. Han , Nathan J. Sniadecki et al.
Journal of Biomechanics, 2016, 49 (13), pp.2625-2634. ⟨10.1016/j.jbiomech.2016.05.031⟩
Journal articles hal-01443843v1
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Computational model combined with in vitro experiments to analyse mechanotransduction during mesenchymal stem cell adhesion

Jean-Louis Milan , Sandrine Lavenus , Paul Pilet , Guy Louarn , Sylvie Wendling et al.
eCells and Materials Journal, 2013, 25, pp.97-113. ⟨10.22203/eCM.v025a07⟩
Journal articles hal-02284008v1
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Computational model combined with in vitro experiments to analyse mechanotransduction during mesenchymal STEM cell adhesion

Jean-Louis Milan , Sandrine Lavenus , Paul Pilet , Guy Louarn , Sylvie Wendling et al.
eCells and Materials Journal, 2013, 25, pp.97
Journal articles hal-00961227v1
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Simulation of bone tissue formation within a porous scaffold under dynamic compression

Josep A. Planell , Jean-Louis Milan , Josep Planell , Damien Lacroix
Biomechanics and Modeling in Mechanobiology, 2010, 9 (5), pp.583 - 596. ⟨10.1007/s10237-010-0199-5⟩
Journal articles hal-01635758v1
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Computational modelling of the mechanical environment of osteogenesis within a polylactic acid–calcium phosphate glass scaffold

Jean-Louis Milan , Josep A. Planell , Damien Lacroix
Biomaterials, 2009, 30 (25), pp.4219 - 4226. ⟨10.1016/j.biomaterials.2009.04.026⟩
Journal articles hal-01635756v1
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Divided medium-based model for analyzing the dynamic reorganization of the cytoskeleton during cell deformation

Jean-Louis Milan , Sylvie Wendling-Mansuy , Michel Jean , Patrick Chabrand
Biomechanics and Modeling in Mechanobiology, 2007, 6 (6), pp.373-390. ⟨10.1007/s10237-006-0057-7⟩
Journal articles hal-00475545v1

Curvature-dependent mesenchymal cells and epithelial tissue migration and orientation

Laurent Pieuchot , Pablo Rougerie , Maxime Vassaux , Julie Marteau , Pierre-François Chauvy et al.
Interface Biology of Implants IBI 2019, May 2019, Rostock, Germany
Conference papers hal-02175659v1

La curvotaxie ou comment la migration des cellules est dirigée par la courbure de leur environnement

Laurent Pieuchot , Maxime Vassaux , Alain Guignandon , Julie Marteau , Jean-Louis Milan et al.
Matériaux 2018, Nov 2018, Strasbourg, France
Conference papers hal-02188974v1

How cells surf the waves? Curvotaxis directs migration trough cell-scale natural landscapes

Laurent Pieuchot , Maxime Vassaux , Julie Marteau , Thomas Cloatre , Tatiana Petithory et al.
American Society for Cell Biology C.1 Materials, Surfaces and Interfaces for Medical Applications and Health, Dec 2016, San Francisco, United States
Conference papers hal-02175663v1

Cytoskeleton dynamical behaviour approached by a granular tensegrity model.

Jean-Louis Milan , Sylvie Wendling Mansuy , Michel Jean , Patrick Chabrand
20th Congress of the International Society of Biomechanics, Jul 2005, Cleveland, United States
Conference papers hal-00479999v1

Granular medium to analyze cytoskeleton mechanics

Jean-Louis Milan , Sylvie Wendling Mansuy , Michel Jean , Patrick Chabrand
Cell Biomechanics Meeting, Sep 2005, Paris, France
Conference papers hal-00479997v1
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Designing Optimal Scaffold Topographies to Promote Nucleus-Guided Mechanosensitive Cell Migration Using in Silico Models

Maxime Vassaux , Laurent Pieuchot , Karine Anselme , Maxence Bigerelle , Jean-Louis Milan et al.
Developments and Novel Approaches in Biomechanics and Metamaterials, 132, Springer International Publishing, pp.199-216, 2020, Advanced Structured Materials, 978-3-030-50464-9. ⟨10.1007/978-3-030-50464-9_12⟩
Book sections hal-03475182v1