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JM
Jean-Louis Milan
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Documents
Identifiants chercheurs
- jean-louis-milan
- 0000-0001-5191-3094
- IdRef : 124313736
Présentation
I have begun developing computational modelling of cytoskeleton dynamics to understand how the cells adapt their structure to their environment. I have succeed in proposing mechanisms of cell adhesion and cell migration guided by substrate shape. Based on these results of our models that reproduced observed phenomenon on static cellular environment, I have built the idea of upgrading the models into avatars of cell to develop strategies for tissue engineering based on in silico live predicting tool that a are able to guide cell functions into dynamic cellular environments.
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Actomyosin, vimentin and LINC complex pull on osteosarcoma nuclei to deform on micropillar topographyBiomaterials, 2020, 234, pp.119746. ⟨10.1016/j.biomaterials.2019.119746⟩
Article dans une revue
hal-02525268v1
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