Jean-Marie PELOPONESE

Documents

Publications

Valproate reactivates HTLV-1 tax and reduces ABCB1/MDR1 expression in PBMCs derived from ATLL patients

Célima Mourouvin , Julie Tram , Laetitia Marty , Anika Marie-Delcasse , Gildas Belrose et al.

Frontiers in Oncology, 2026, 16, ⟨10.3389/fonc.2026.1721313⟩

Article dans une revue hal-05767142v1

The Oncoprotein Fra-2 Drives the Activation of Human Endogenous Retrovirus Env Expression in Adult T-Cell Leukemia/Lymphoma (ATLL) Patients

Julie Tram , Laetitia Marty , Célima Mourouvin , Magali Abrantes , Ilham Jaafari et al.

Cells, 2024, 13 (18), pp.1517. ⟨10.3390/cells13181517⟩

Article dans une revue hal-04693875v1

The helicase-like transcription factor redirects the autophagic flux and restricts human T cell leukemia virus type 1 infection

Aurélie Beauvois , Hélène Gazon , Pradeep Singh Chauhan , Majeed Jamakhani , Jean-Rock Jacques et al.

Proceedings of the National Academy of Sciences of the United States of America, 2023, 120 (31), pp.e2216127120. ⟨10.1073/pnas.2216127120⟩

Article dans une revue hal-04277558v1

Murine leukemia virus (MLV) P50 protein induces cell transformation via transcriptional regulatory function

Charbel Akkawi , Jerome Feuillard , Felipe Leon Diaz , Khalid Belkhir , Nelly Godefroy et al.

Retrovirology, 2023, 20 (1), pp.16. ⟨10.1186/s12977-023-00631-w⟩

Article dans une revue hal-04235300v1

Alternative RNA splicing in cancer: what about adult T-cell leukemia?

Julie Tram , Jean-Michel Mesnard , Jean-Marie Peloponese

Frontiers in Immunology, 2022, 13, pp.959382. ⟨10.3389/fimmu.2022.959382⟩

Article dans une revue (article de synthèse) hal-04277550v1

A newly identified interaction between nucleolar NPM1/B23 and the HTLV-I basic leucine zipper factor in HTLV-1 infected cells

Zhenlong Liu , Émilie Larocque , Yongli Xie , Yong Xiao , Guy Lemay et al.

Frontiers in Microbiology, 2022, 13, pp.988944. ⟨10.3389/fmicb.2022.988944⟩

Article dans une revue hal-03923108v2

The HTLV-1 viral oncoproteins Tax and HBZ reprogram the cellular mRNA splicing landscape

Charlotte Vandermeulen , Tina O’grady , Jerome Wayet , Bartimee Galvan , Sibusiso Maseko et al.

PLoS Pathogens, 2021, 17 (9), pp.e1009919. ⟨10.1371/journal.ppat.1009919⟩

Article dans une revue hal-03400504v1

Exploring hTERT promoter methylation in cutaneous T‐cell lymphomas

Alain Chebly , Joana Ropio , Jean-Marie Peloponese , Sandrine Poglio , Martina Prochazkova‐carlotti et al.

Molecular Oncology, 2021, ⟨10.1002/1878-0261.12946⟩

Article dans une revue hal-03400510v1

hMZF-2, the Elusive Transcription Factor

Alain Chebly , Jean-Marie Peloponese , Evelyne Ségal-Bendirdjian , Jean-Philippe Merlio , Roland Tomb et al.

Frontiers in Genetics, 2020, 11, ⟨10.3389/fgene.2020.581115⟩

Article dans une revue hal-03436699v1

Collagen IV (COL4A1, COL4A2), a Component of the Viral Biofilm, Is Induced by the HTLV-1 Oncoprotein Tax and Impacts Virus Transmission

Sebastian Millen , Christine Gross , Norbert Donhauser , Melanie Mann , Jean-Marie Peloponese et al.

Frontiers in Microbiology, 2019, 10, ⟨10.3389/fmicb.2019.02439⟩

Article dans une revue hal-02347336v1

The Host DHX9 DExH-Box Helicase Is Recruited to Chikungunya Virus Replication Complexes for Optimal Genomic RNA Translation

Roy Matkovic , Eric Bernard , Simon Fontanel , Patrick Eldin , Nathalie Chazal et al.

Journal of Virology, 2019, 93 (4), ⟨10.1128/jvi.01764-18⟩

Article dans une revue (data paper) hal-05471262v1

The Host DHX9 DExH-Box Helicase Is Recruited to Chikungunya Virus Replication Complexes for Optimal Genomic RNA Translation

Roy Matkovic , Eric Bernard , Simon Fontanel , Patrick Eldin , Nathalie Chazal et al.

Journal of Virology, 2019, 93 (4), pp.1764 - 1782. ⟨10.1128/JVI.01764-18⟩

Article dans une revue hal-02147108v1

HTLV-1 basic leucine zipper factor protects cells from oxidative stress by upregulating expression of Heme Oxygenase I

Amanda W. Rushing , Blake Rushing , Kimson Hoang , Stephanie Sanders , Jean-Marie Peloponese et al.

PLoS Pathogens, 2019, 15 (6), pp.e1007922. ⟨10.1371/journal.ppat.1007922⟩

Article dans une revue hal-02347284v1

Hijacking of the AP-1 Signaling Pathway during Development of ATL

Hélène Gazon , Benoit Barbeau , Jean-Michel Mesnard , Jean-Marie Peloponese

Frontiers in Microbiology, 2018, 8, pp.2686. ⟨10.3389/fmicb.2017.02686⟩

Article dans une revue hal-02120102v1

HBZ-mediated shift of JunD from growth suppressor to tumor promoter in leukemic cells by inhibition of ribosomal protein S25 expression

M Terol , H Gazon , I Lemasson , M Duc-Dodon , B Barbeau et al.

Leukemia, 2017, 31 (10), pp.2235-2243. ⟨10.1038/leu.2017.74⟩

Article dans une revue hal-02120104v1

Differential Effects of AZD-1208 and SMI-4a, Two Pim-1 Kinase Inhibitors on Primary HAM/TSP and ATL Cells

D Jean-Baptiste , G Belrose , Jc Meniane , A Lézin , S Jeannin et al.

Annals of Carcinogenesis, 2017

Article dans une revue hal-02137872v1

Reducing the global burden of HTLV-1 infection: An agenda for research and action

Luc Willems , Hideki Hasegawa , Roberto Accolla , Charles Bangham , Ali Bazarbachi et al.

Antiviral Research, 2017, 137, pp.41-48. ⟨10.1016/j.antiviral.2016.10.015⟩

Article dans une revue hal-02137848v1

Impaired expression of DICER and some microRNAs in HBZ expressing cells from acute adult T-cell leukemia patients

Hélène Gazon , Gildas Belrose , Marie Terol , Jean-Come Meniane , Jean-Michel Mesnard et al.

Oncotarget, 2016, 7 (21), ⟨10.18632/oncotarget.7162⟩

Article dans une revue hal-02120105v1

Roles of HTLV-1 basic Zip Factor (HBZ) in Viral Chronicity and Leukemic Transformation. Potential New Therapeutic Approaches to Prevent and Treat HTLV-1-Related Diseases

Jean-Michel Mesnard , Benoit Barbeau , Raymond Césaire , Jean-Marie Peloponese

Viruses, 2015, 7 (12), pp.6490-6505. ⟨10.3390/v7122952⟩

Article dans une revue hal-02120107v1

HBZ Stimulates Brain-Derived Neurotrophic Factor/TrkB Autocrine/Paracrine Signaling To Promote Survival of Human T-Cell Leukemia Virus Type 1-Infected T Cells

N. Polakowski , M. Terol , K. Hoang , I. Nash , S. Laverdure et al.

Journal of Virology, 2014, 88 (22), pp.13482-13494. ⟨10.1128/JVI.02285-14⟩

Article dans une revue hal-02120111v1

Functional comparison of antisense proteins of HTLV-1 and HTLV-2 in viral pathogenesis

Benoit Barbeau , Jean-Marie Peloponese , Jean-Michel Mesnard

Frontiers in Microbiology, 2013, 4, ⟨10.3389/fmicb.2013.00226⟩

Article dans une revue hal-02120116v1

Increased osteopontin expression in HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) patient cells is associated with IL-17 expression

Sarkis Sarkis , Gildas Belrose , Jean-Marie Peloponese , Stéphane Olindo , Raymond Césaire et al.

Journal of Clinical Virology, 2013, 58 (1), pp.295-298. ⟨10.1016/j.jcv.2013.05.006⟩

Article dans une revue istex hal-02146262v1

Human T-Cell Leukemia Virus Type 1 (HTLV-1) bZIP Factor Requires Cellular Transcription Factor JunD To Upregulate HTLV-1 Antisense Transcription from the 3' Long Terminal Repeat

H. Gazon , I. Lemasson , N. Polakowski , R. Césaire , M. Matsuoka et al.

Journal of Virology, 2012, 86 (17), pp.9070-9078. ⟨10.1128/JVI.00661-12⟩

Article dans une revue hal-02120123v1

Effects of valproate on Tax and HBZ expression in HTLV-1 and HAM/TSP T lymphocytes

G. Belrose , A. Gross , S. Olindo , A. Lezin , M. Dueymes et al.

Blood, 2011, 118 (9), pp.2483-2491. ⟨10.1182/blood-2010-11-321364⟩

Article dans une revue hal-02152775v1

Effects of valproate on Tax and HBZ expression in HTLV-1 and HAM/TSP T lymphocytes

Gildas Belrose , Antoine Gross , Stéphane Olindo , Agnès Lézin , Maryvonne Dueymes et al.

Blood, 2011, 118 (9), pp.2483-2491. ⟨10.1182/blood-2010-11-321364⟩

Article dans une revue hal-02146255v1

Induction of reactive oxygen species by human T-cell leukemia virus type 1 tax correlates with DNA damage and expression of cellular senescence marker.

Takao Kinjo , Julia Ham-Terhune , Jean-Marie Peloponese , Kuan-Teh Jeang

Journal of Virology, 2010, 84 (10), pp.5431-7. ⟨10.1128/JVI.02460-09⟩

Article dans une revue hal-00509061v1

Peptidylproline cis-trans isomerase Pin1 interacts with HTLV-1 Tax and modulates its activation of NF-{kappa}B.

Jean-Marie Peloponese , Junichiro Yasunaga , Takao Kinjo , Koichi Watashi , Kuan-Teh Jeang

Journal of Virology, 2009, 83 (7), pp.3238-48. ⟨10.1128/JVI.01824-08⟩

Article dans une revue hal-00358495v1

Inflammatory cardiac valvulitis in TAX1BP1-deficient mice through selective NF-κB activation

Hidekatsu Iha , Jean-Marie Peloponese , Lynn Verstrepen , Grzegorz Zapart , Fumiyo Ikeda et al.

EMBO Journal, 2008, 27 (4), pp.629-641. ⟨10.1038/emboj.2008.5⟩

Article dans une revue hal-02137874v1

Histone Acetyltransferase hALP and Nuclear Membrane Protein hsSUN1 Function in De-condensation of Mitotic Chromosomes

Ya-Hui Chi , Kerstin Haller , Jean-Marie Peloponese , Kuan-Teh Jeang

Journal of Biological Chemistry, 2007, 282 (37), pp.27447-27458. ⟨10.1074/jbc.M703098200⟩

Article dans une revue hal-02137882v1

Heterozygous Deletion of Mitotic Arrest–Deficient Protein 1 (MAD1) Increases the Incidence of Tumors in Mice

Yoichi Iwanaga , Ya-Hui Chi , Akiko Miyazato , Sergey Sheleg , Kerstin Haller et al.

Cancer Research, 2007, 67 (1), pp.160-166. ⟨10.1158/0008-5472.CAN-06-3326⟩

Article dans une revue hal-02137886v1

Evidence for Cooperative Transforming Activity of the Human Pituitary Tumor Transforming Gene and Human T-Cell Leukemia Virus Type 1 Tax

Sergey Sheleg , Jean-Marie Peloponese , Ya-Hui Chi , Yan Li , Michael Eckhaus et al.

Journal of Virology, 2007, 81 (15), pp.7894-7901. ⟨10.1128/JVI.00555-07⟩

Article dans une revue hal-02137885v1

Modulation of Nuclear Factor-κB by Human T Cell Leukemia Virus Type 1 Tax Protein: Implications for Oncogenesis and Inflammation

Jean-Marie Peloponese , Man Lung Yeung , Kuan-Teh Jeang

Immunologic Research, 2006, 34 (1), pp.1-12. ⟨10.1385/IR:34:1:1⟩

Article dans une revue istex hal-02137890v1

Role for Akt/Protein Kinase B and Activator Protein-1 in Cellular Proliferation Induced by the Human T-cell Leukemia Virus Type 1 Tax Oncoprotein

Jean-Marie Peloponese , Kuan-Teh Jeang

Journal of Biological Chemistry, 2006, 281 (13), pp.8927-8938. ⟨10.1074/jbc.M510598200⟩

Article dans une revue hal-02137889v1

The N-terminus of rodent and human MAD1 confers species-specific stringency to spindle assembly checkpoint

Jean-Marie Peloponese , V Haller , V Kibler , T Kasai , Y-H Chi et al.

Oncogene, 2006, 25 (15), pp.2137-2147. ⟨10.1038/sj.onc.1209259⟩

Article dans une revue hal-02137894v1

Abnormal centrosome amplification in cells through the targeting of Ran-binding protein-1 by the human T cell leukemia virus type-1 Tax oncoprotein

Jean-Marie Peloponese , Kerstin Haller , Akiko Miyazato , Kuan-Teh Jeang

Proceedings of the National Academy of Sciences of the United States of America, 2005, 102 (52), pp.18974-18979. ⟨10.1073/pnas.0506659103⟩

Article dans une revue hal-02137892v1

Full-length HIV-1 Tat protein necessary for a vaccine

Sandrine Opi , Jean-Marie Peloponese , Didier Esquieu , Jennifer Watkins , Grant Campbell et al.

Vaccine, 2004, 22 (23-24), pp.3105-3111. ⟨10.1016/j.vaccine.2004.01.057⟩

Article dans une revue istex hal-02137961v1

Ubiquitination of Human T-Cell Leukemia Virus Type 1 Tax Modulates Its Activity

Jean-Marie Peloponese , Hidekatsu Iha , Venkat Yedavalli , Akiko Miyazato , Yan Li et al.

Journal of Virology, 2004, 78 (21), pp.11686-11695. ⟨10.1128/JVI.78.21.11686-11695.2004⟩

Article dans une revue hal-02137895v1

A possible improvement for structure-based drug design illustrated by the discovery of a Tat HIV-1 inhibitor

Mickaël Montembault , Giang Vo-Thanh , Abdallah Deyine , Valérie Fargeas , Monique Villiéras et al.

Bioorganic and Medicinal Chemistry Letters, 2004, 14 (6), pp.1543-1546. ⟨10.1016/j.bmcl.2003.12.095⟩

Article dans une revue istex hal-02137964v1

A non-proteolytic role for ubiquitin in Tat-mediated transactivation of the HIV-1 promoter

Vanessa Brès , Rosemary Kiernan , Laetitia Linares , Christine Chable-Bessia , Olga Plechakova et al.

Nature Cell Biology, 2003, 5 (8), pp.754-761. ⟨10.1038/ncb1023⟩

Article dans une revue istex hal-02137972v1

Segregation of NF-κB activation through NEMO/IKKγ by Tax and TNFα: implications for stimulus-specific interruption of oncogenic signaling

Hidekatsu Iha , Karen Kibler , Venkat Yedavalli , Jean-Marie Peloponese , Kerstin Haller et al.

Oncogene, 2003, 22 (55), pp.8912-8923. ⟨10.1038/sj.onc.1207058⟩

Article dans une revue hal-02137967v1

Tat HIV-1 Primary and Tertiary Structures Critical to Immune Response Against Non-homologous Variants

Sandrine Opi , Jean-Marie Peloponese , Didier Esquieu , Grant Campbell , Jean de Mareuil et al.

Journal of Biological Chemistry, 2002, 277 (39), pp.35915-35919. ⟨10.1074/jbc.M204393200⟩

Article dans une revue hal-02137976v1

Homonuclear 1 H-NMR assignment and structural characterization of human immunodeficiency virus type 1 Tat Mal protein

Catherine Grégoire , Jean-Marie Peloponese , Didier Esquieu , Sandrine Opi , Grant Campbell et al.

Biopolymers, 2001, 62 (6), pp.324-335. ⟨10.1002/bip.10000⟩

Article dans une revue istex hal-02137978v1

1H-13C nuclear magnetic resonance assignment and structural characterization of HIV-1 Tat protein.

Jean-Marie Peloponese , C. Gregoire , S Opi , E Esquieu , James N. Sturgis et al.

Comptes Rendus de l'Académie des Sciences - Series III - Sciences de la Vie, 2000, 323 (10), pp.883-94. ⟨10.1016/S0764-4469(00)01228-2⟩

Article dans une revue istex hal-02137980v1

Full Peptide Synthesis, Purification, and Characterization of Six Tat Variants

Jean-Marie Peloponese , Yves Collette , Catherine Grégoire , Christian Bailly , Daniel Campèse et al.

Journal of Biological Chemistry, 1999, 274 (17), pp.11473-11478. ⟨10.1074/jbc.274.17.11473⟩

Article dans une revue hal-02137983v1

TERT Hypermethylated Oncogenic Region, A new player in the activation of the hTERT gene in cutaneous T-cell lymphomas.

Alain Chebly , Joana Ropio , Jean-Marie Peloponese , Sandrine Poglio , Martina Prochazkova-Carlotti et al.

European Society of Human Genetics (ESHG). 53rd European Society of Human Genetics (ESHG) Conference, Jun 2020, Virtuel - Online, France. Springer Nature, European Journal of Human Genetics, 28 (Suppl. 1), pp.1005-1006 / E-P24.24, 2020

Poster de conférence hal-05308649v1

Antagonistic regulation of HBZ splicing by hnRNPA1 and hnRNPH1 drives HTLV-1 leukemogenesis

Julie Tram , Célima Mourouvin , Laetitia Marty , Anika Marie-Delcasse , Arnaud Lecante et al.

2026

Pré-publication, Document de travail hal-05767154v1

Transcriptional rewiring of NF-κB by HBZ and Fra-2 drives inflammatory chemoresistance in Tax-negative adult T-cell leukemia/lymphoma

Julie Tram , Laetitia Marty , Celima Mourouvin , Magali Abrantes , Raymond Cesaire et al.

2026

Pré-publication, Document de travail hal-05775763v1

A new HIV-1 latency reversing agent activating HIV-Tat

Phuoc Bao Viet Tong , Laetitia Marty , Nawel Chekrit , Martine Pugnière , Jean-Marie Péloponèse et al.

2026

Pré-publication, Document de travail hal-05767151v1

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