Jean-Michel Escoffre

54%
Libre accès
106
Documents
Affiliation actuelle
  • Imaging, Brain & Neuropsychiatry (iBraiN)

Présentation

Jean-Michel Escoffre earned his M.Sc. degrees in Vectorology, Gene Therapy, Vaccinology and in Structure/Function in Macromolecules and Living Processes in 2005 and 2006 respectively, at the University Paul-Sabatier (Toulouse, France). He obtained his Ph.D. degrees in Cell Biophysics in 2010 at the Institute of Pharmacology and Structural Biology (IPBS/CNRS, UMR 5089) and University Paul-Sabatier. During his PhD fellowship, he investigated the molecular and cellular mechanisms of gene electrotransfer. For his first post-doctoral fellowship, he joined the Institute of Imaging and Brain of the French Institute for Health and Medical Science (Inserm, UMR 930) in Tours, France (2010-2013). He worked in the fields of gene and drug delivery using microbubble-assisted ultrasound. Then, he joined the Imaging Division at UMC Utrecht, The Netherlands. His main research interest was the development of HIFU-mediated anticancer immunotherapy (2013-2015). He is currently pursuing his research as Inserm Senior Researcher at the Institute of Imaging and Brain of the French Institute for Health and Medical Science (Inserm, University of Tours) in Tours, France. His main research interest lie in the fields of biodrug delivery using ultrasound-guided therapeutic ultrasound. Jean-Michel Escoffre is also expert in Diagnostic Tools, Therapies and Public Health for many national, European and international public and private agencies.


Compétences

Ultrasound imaging ultrasound sonoporation drug delivery ultrasound neuromodulation

Publications

Publications

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Numerical modeling of ultrasound propagation in the inner ear for sonoporation-mediated drug delivery

Fabrice Micaletti , David Bakhos , Jean-Michel Escoffre , Dapeng Li , Ayache Bouakaz et al.
Applied Physics Letters, 2025, 126 (2), pp.024101. ⟨10.1063/5.0239956⟩
Article dans une revue inserm-04891735 v1
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Intracerebral drug delivery using microbubble/nanodroplet-assisted ultrasound to address neurodegenerative diseases

Karen Ea , Nicolas Taulier , Christiane Contino-Pépin , Wladimir Urbach , Stéphane Desgranges et al.
Journal of Clinical and Translational Research, 2025, pp.00061. ⟨10.36922/jctr.24.00061⟩
Article dans une revue hal-04974610 v1
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Delivery of Anticancer Drugs Using Microbubble-Assisted Ultrasound in a 3D Spheroid Model

Marie Roy , Corentin Alix , Julien Burlaud-Gaillard , Damien Fouan , William Raoul et al.
Molecular Pharmaceutics, 2024, Online ahead of print. ⟨10.1021/acs.molpharmaceut.3c00921⟩
Article dans une revue inserm-04374054 v1
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Enhanced macromolecular substance extravasation through the blood-brain barrier via acoustic bubble-cell interactions

Jifan Chen , Jean-Michel Escoffre , Oliver Romito , Tarik Iazourene , Antoine Presset et al.
Ultrasonics Sonochemistry, 2024, 103, pp.106768. ⟨10.1016/j.ultsonch.2024.106768⟩
Article dans une revue inserm-04425434 v1
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Microbubble-assisted ultrasound for inner ear drug delivery

Fabrice Micaletti , Jean-Michel Escoffre , Sandrine Kerneis , Ayache Bouakaz , John Galvin et al.
Advanced Drug Delivery Reviews, 2024, 204, pp.115145. ⟨10.1016/j.addr.2023.115145⟩
Article dans une revue inserm-04333190 v1
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Metabolomic profile of cerebral tissue after acoustically-mediated blood-brain barrier opening in a healthy rat model: a focus on the contralateral side

Antoine Presset , Sylvie Bodard , Antoine Lefèvre , Anaïs Millet , Edward Oujagir et al.
Frontiers in Molecular Neuroscience, 2024, 17, pp.1383963. ⟨10.3389/fnmol.2024.1383963⟩
Article dans une revue inserm-04795005 v1
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Sonoporation of the Round Window Membrane on a Sheep Model: A Safety Study

Sandrine Kerneis , Jean-Michel Escoffre , John J Galvin , Ayache Bouakaz , Antoine Presset et al.
Pharmaceutics, 2023, 15 (2), pp.442. ⟨10.3390/pharmaceutics15020442⟩
Article dans une revue inserm-03964324 v1
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Tumor Spheroids as Model to Design Acoustically Mediated Drug Therapies: A Review

Marie Roy , Corentin Alix , Ayache Bouakaz , Sophie Serrière , Jean-Michel Escoffre
Pharmaceutics, 2023, 15 (3), pp.806. ⟨10.3390/pharmaceutics15030806⟩
Article dans une revue inserm-04032858 v1
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First Metabolomic Signature of Blood-Brain Barrier Opening Induced by Microbubble-Assisted Ultrasound

Antoine Presset , Sylvie Bodard , Antoine Lefèvre , Anaïs Millet , Edward Oujagir et al.
Frontiers in Molecular Neuroscience, 2022, 15, pp.888318. ⟨10.3389/fnmol.2022.888318⟩
Article dans une revue inserm-03707049 v1
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Microbubble-assisted ultrasound for imaging and therapy of melanoma skin cancer: A systematic review

François Avry , Coralie Mousset , Edward Oujagir , Ayache Bouakaz , Valérie Gouilleux-Gruart et al.
Ultrasound in Medicine & Biology, In press, 48 (11), pp.2174-2198. ⟨10.1016/j.ultrasmedbio.2022.06.021⟩
Article dans une revue inserm-03707096 v1
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Ultrasound Neurostimulation in Mice: Impact of Ultrasound Settings and Beam Properties

Jean-Michel Escoffre , Ayache Bouakaz , Tarik Iazourène , Hanaa Malloul , Edward Oujagir et al.
IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control, 2022, Ahead of print
Article dans une revue inserm-03528841 v1
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Delivery of anti-cancer drugs using microbubble-assisted ultrasound in digestive oncology: From preclinical to clinical studies

Jean-Michel Escoffre , Najib Sekkat , Edward Oujagir , Sylvie Bodard , Coralie Mousset et al.
Expert Opinion on Drug Delivery, 2022, Online ahead of print. ⟨10.1080/17425247.2022.2061459⟩
Article dans une revue inserm-03626073 v1
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Taking Advantages of Blood–Brain or Spinal Cord Barrier Alterations or Restoring Them to Optimize Therapy in ALS?

Hugo Alarcan , Yara Al Ojaimi , Debora Lanznaster , Jean-Michel Escoffre , Philippe Corcia et al.
Journal of Personalized Medicine, 2022, 12, pp.1071. ⟨10.3390/jpm12071071⟩
Article dans une revue inserm-03723283 v1
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Acoustic and Elastic Properties of a Blood Clot during Microbubble-Enhanced Sonothrombolysis: Hardening of the Clot with Inertial Cavitation

Laurent Auboire , Damien Fouan , Jean-Marc Grégoire , Fréderic Ossant , Camille Plag et al.
Pharmaceutics, 2021, 13, pp.1566. ⟨10.3390/pharmaceutics13101566⟩
Article dans une revue inserm-03354808 v1
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Voluntary Wheel Running Does Not Enhance Radiotherapy Efficiency in a Preclinical Model of Prostate Cancer: The Importance of Physical Activity Modalities?

Suzanne Dufresne , Cindy Richard , Arthur Dieumegard , Luz Orfila , Gregory Delpon et al.
Cancers, 2021, 13 (21), pp.5402. ⟨10.3390/cancers13215402⟩
Article dans une revue inserm-03409985 v1
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A systematic review of ultrasound imaging and therapy in mental disorders

Marta Andrea Siragusa , Jean-Pierre Remenieras , Ayache Bouakaz , Jean-Michel Escoffre , Frédéric Patat et al.
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2020, 101, pp.109919. ⟨10.1016/j.pnpbp.2020.109919⟩
Article dans une revue inserm-02519433 v1
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Ultrasound-responsive cavitation nuclei for therapy and drug delivery

Klazina Kooiman , Silke Roovers , Simone a G Langeveld , Robert T Kleven , Heleen Dewitte et al.
Ultrasound in Medicine & Biology, In press
Article dans une revue inserm-02437994 v1
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Endothelial Cells, First Target of Drug Delivery Using Microbubble-Assisted Ultrasound

Antoine Presset , Corentin Bonneau , Sasaoka Kazuyoshi , Lydie Nadal-Desbarats , Takigucho Mitsuyoshi et al.
Ultrasound in Medicine & Biology, 2020, Online ahead of print. ⟨10.1016/j.ultrasmedbio.2020.03.013⟩
Article dans une revue inserm-02565367 v1
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New insights on the role of ROS in the mechanisms of sonoporation-mediated gene delivery

Jean-Michel Escoffre , Pablo Campomanes , Mounir Tarek , Ayache Bouakaz
Ultrasonics Sonochemistry, 2020, 64, pp.104998. ⟨10.1016/j.ultsonch.2020.104998⟩
Article dans une revue inserm-02488866 v1
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Editorial: Bubbles, Droplets and Micelles for Acoustically-Mediated Drug/Gene Delivery

Jean-Michel Escoffre , Baudouin Denis de Senneville , Noboru Sasaki , Marc Derieppe
Frontiers in Pharmacology, 2020, 11, pp.954. ⟨10.3389/fphar.2020.00954⟩
Article dans une revue inserm-02915877 v1
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Enhanced Amikacin Diffusion With Ultrasound and Microbubbles in a Mechanically Ventilated Condensed Lung Rabbit Model

Fabien Espitalier , François Darrouzain , Jean-Michel Escoffre , David Ternant , Eric Piver et al.
Frontiers in Pharmacology, 2020, 10, pp.1562. ⟨10.3389/fphar.2019.01562⟩
Article dans une revue inserm-02441635 v1
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Assessment of Intratumoral Doxorubicin Penetration after Mild Hyperthermia-mediated Release from Thermosensitive Liposomes

Marc Derieppe , Jean-Michel Escoffre , Baudouin Denis de Senneville , Quincy van Houtum , Angelique Barten-van Rijbroek et al.
Contrast Media and Molecular Imaging, 2019, ⟨10.1155/2019/2645928⟩
Article dans une revue hal-02377672 v1
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Minireview: Biophysical Mechanisms of Cell Membrane Sonopermeabilization. Knowns and Unknowns

Jean-Michel Escoffre , Ayache Bouakaz
Langmuir, 2019, 35 (31), pp.10151-10165. ⟨10.1021/acs.langmuir.8b03538⟩
Article dans une revue inserm-02438144 v1
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Experience implication in subjective surgical ergonomics comparison between laparoscopic and robot-assisted surgeries

V. Mendes , Franck Bruyère , Jean-Michel Escoffre , Aurélien Binet , Hubert Lardy et al.
Journal of Robotic Surgery, 2019, ⟨10.1007/s11701-019-00933-2⟩
Article dans une revue inserm-02438134 v1
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Quantitative Ultrasound in Ex Vivo Fibrotic Rabbit Livers

Emilie Franceschini , Jean-Michel Escoffre , Anthony Novell , Laurent Auboire , Vanda Mendes et al.
Ultrasound in Medicine & Biology, 2019, 45 (7), pp.1777-1786. ⟨10.1016/j.ultrasmedbio.2019.02.013⟩
Article dans une revue hal-02200101 v1
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Enhancing Nab-Paclitaxel Delivery Using Microbubble-Assisted Ultrasound in a Pancreatic Cancer Model

Diane Bressand , Anthony Novell , Alban Girault , William Raoul , Gaëlle Fromont-Hankard et al.
Molecular Pharmaceutics, 2019, 16 (9), pp.3814-3822. ⟨10.1021/acs.molpharmaceut.9b00416⟩
Article dans une revue hal-02301225 v1

Comment on “The Enhancing Effect of Focused Ultrasound on TNK-Tissue Plasminogen Activator-Induced Thrombolysis using an In Vitro Circulating Flow Model”

Laurent Auboire , Jean-Michel Escoffre
Journal of Stroke and Cerebrovascular Diseases, 2019, 28 (7), pp.2052. ⟨10.1016/j.jstrokecerebrovasdis.2019.03.039⟩
Article dans une revue inserm-02438124 v1
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Microbubbles combined with ultrasound therapy in ischemic stroke: A systematic review of in-vivo preclinical studies

Laurent Auboire , Charles Sennoga , Jean-Marc Hyvelin , Frédéric Ossant , Jean-Michel Escoffre et al.
PLoS ONE, 2018, 13 (2), pp.e0191788. ⟨10.1371/journal.pone.0191788⟩
Article dans une revue hal-01761337 v1
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Development of a Fluid Dynamic Model for Quantitative Contrast-Enhanced Ultrasound Imaging

Baudouin Denis de Senneville , Anthony Novell , Chloé J. Arthuis , Vanda Mendes , Paul-Armand Dujardin et al.
IEEE Transactions on Medical Imaging, 2018, 37 (2), pp.372-383
Article dans une revue hal-01962485 v1

Experimental Implementation of a Pulse Compression Technique Using Coherent Plane-Wave Compounding

Yanis Mehdi Benane , Denis Bujoreanu , Roberto J Lavarello , F. Varray , Jean-Michel Escoffre et al.
IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control, 2018, 65 (6), pp.1025 - 1036. ⟨10.1109/TUFFC.2018.2820747⟩
Article dans une revue hal-01957676 v1
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Microbubble-Assisted Ultrasound-Induced Transient Phosphatidylserine Translocation

Jean-Michel Escoffre , Marc Derieppe , Bart Lammertink , Clemens Bos , Chrit Moonen
Ultrasound in Medicine & Biology, 2017, 43 (4), pp.838-851. ⟨10.1016/j.ultrasmedbio.2016.12.002⟩
Article dans une revue inserm-02438167 v1
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Evaluation of high resolution ultrasound as a tool for assessing the 3D volume of blood clots during in vitro thrombolysis

Laurent Auboire , Jean-Michel Escoffre , Damien Fouan , Jean-René Jacquet , Frédéric Ossant et al.
Scientific Reports, 2017, 7 (1), pp.6211. ⟨10.1038/s41598-017-06089-z⟩
Article dans une revue inserm-02438161 v1
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Real-Time Monitoring of Placental Oxygenation during Maternal Hypoxia and Hyperoxygenation Using Photoacoustic Imaging

Chloé J. Arthuis , Anthony Novell , Florian Raes , Jean-Michel Escoffre , Stéphanie Lerondel et al.
PLoS ONE, 2017, 12 (1), pp.e0169850. ⟨10.1371/journal.pone.0169850⟩
Article dans une revue inserm-02438173 v1

Microbubble-mediated ultrasound drug-delivery and therapeutic monitoring

Charles Sennoga , Emma Kanbar , Laurent Auboire , Paul-Armand Dujardin , Damien Fouan et al.
Expert Opinion on Drug Delivery, 2016, 14 (9), pp.1031-1043. ⟨10.1080/17425247.2017.1266328⟩
Article dans une revue inserm-02438187 v1
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Formulation and Pharmacokinetics of Thermosensitive Stealth® Liposomes Encapsulating 5-Fluorouracil

Chantal Al Sabbagh , Nicolas Tsapis , Anthony Novell , Patricia Calleja-Gonzalez , Jean-Michel Escoffre et al.
Pharmaceutical Research, 2015, 32 (5), pp.1585-1603. ⟨10.1007/s11095-014-1559-0⟩
Article dans une revue inserm-02438401 v1
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Recruitment of endocytosis in sonopermeabilization-mediated drug delivery: A real-time study

Marc Derieppe , Katarzyna Rojek , Jean-Michel Escoffre , Baudouin Denis de Senneville , Chrit T. W. Moonen et al.
Physical Biology, 2015
Article dans une revue hal-01159814 v1

Focused ultrasound influence on calcein-loaded thermosensitive stealth liposomes

Anthony Novell , Chantal Al Sabbagh , Jean-Michel Escoffre , Cedric Gaillard , Nicolas Tsapis et al.
International Journal of Hyperthermia, 2015, 31 (4), pp.349-358. ⟨10.3109/02656736.2014.1000393⟩
Article dans une revue inserm-02438261 v1

Recruitment of endocytosis in sonopermeabilization-mediated drug delivery: a real-time study

Marc Derieppe , Katarzyna Rojek , Jean-Michel Escoffre , Baudouin Denis de Senneville , Chrit Moonen et al.
Physical Biology, 2015, 12 (4), pp.046010. ⟨10.1088/1478-3975/12/4/046010⟩
Article dans une revue inserm-02438247 v1
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Development of a tumor tissue-mimicking model with endothelial cell layer and collagen gel for evaluating drug penetration

Noboru Sasaki , Clemens Bos , Jean-Michel Escoffre , Gert Storm , Chrit Moonen
International Journal of Pharmaceutics, 2015, 482 (1-2), pp.118-122. ⟨10.1016/j.ijpharm.2015.01.039⟩
Article dans une revue inserm-02438274 v1
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Sonochemotherapy: from bench to bedside

Bart Lammertink , Clemens Bos , Roel Deckers , Gert Storm , Chrit Moonen et al.
Frontiers in Pharmacology, 2015, 6, ⟨10.3389/fphar.2015.00138⟩
Article dans une revue inserm-02438239 v1
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Role of endocytosis in sonoporation-mediated membrane permeabilization and uptake of small molecules: a electron microscopy study

A Zeghimi , Jean-Michel Escoffre , Ayache Bouakaz
Physical Biology, 2015, 12 (6), pp.066007. ⟨10.1088/1478-3975/12/6/066007⟩
Article dans une revue inserm-02438214 v1

Mild hyperthermia influence on Herceptin® properties

Jean-Michel Escoffre , Roel Deckers , Noboru Sasaki , Clemens Bos , Chrit Moonen
Journal of Radiology and Oncology, 2015, 49 (1), pp.41-49. ⟨10.2478/raon-2014-0045⟩
Article dans une revue inserm-02438251 v1

Evaluation of chirp reversal power modulation sequence for contrast agent imaging

Novell Anthony , Charles Sennoga , Jean-Michel Escoffre , Jennifer Chaline , Ayache Bouakaz
Physics in Medicine and Biology, 2014, 59 (17), pp.5101-5117. ⟨10.1088/0031-9155/59/17/5101⟩
Article dans une revue inserm-02438448 v1

Serum influence on in-vitro gene delivery using microbubble-assisted ultrasound

Aya Zeghimi , Novell Anthony , Rose-Anne Thepault , Patrick Vourc'H , Ayache Bouakaz et al.
Journal of Drug Targeting, 2014, 22 (8), pp.748-760. ⟨10.3109/1061186X.2014.921922⟩
Article dans une revue inserm-02438479 v1

Membrane disorder and phospholipid scrambling in electropermeabilized and viable cells

Jean-Michel Escoffre , Elisabeth Bellard , Cécile Faurie , Sarah C. Sébaï , Muriel Golzio et al.
Biochimica et Biophysica Acta:Biomembranes, 2014, 1838 (7), pp.1701-1709. ⟨10.1016/j.bbamem.2014.02.013⟩
Article dans une revue inserm-02438553 v1

Evidence for electro-induced membrane defects assessed by lateral mobility measurement of a GPi anchored protein

Jean-Michel Escoffre , Marie Hubert , Justin Teissié , Marie-Pierre Rols , Cyril Favard
European Biophysics Journal, 2014, 43 (6-7), pp.277-286. ⟨10.1007/s00249-014-0961-1⟩
Article dans une revue inserm-02438517 v1

Microbubble attenuation and destruction: are they involved in sonoporation efficiency?

Jean-Michel Escoffre , Novell Anthony , Julien Piron , Aya Zeghimi , Alexander A Doinikov
IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control, 2013, 60 (1), ⟨10.1109/TUFFC.2013.2536⟩
Article dans une revue inserm-02438857 v1

Effect of different parameters used for in vitro gene electrotransfer on gene expression efficiency, cell viability and visualization of plasmid DNA at the membrane level

Sasa Haberl , Masa Kanduser , Karel Flisar , Dusa Hodzic , Vladimir Bostjan Bregar et al.
The Journal of Gene Medicine, 2013, 15 (5), pp.169-181. ⟨10.1002/jgm.2706⟩
Article dans une revue istex inserm-02438609 v1

Bleomycin delivery into cancer cells in vitro with ultrasound and SonoVue® or BR14® microbubbles

Nerijus Lamanauskas , Novell Anthony , Jean-Michel Escoffre , Mindaugas Venslauskas , Saulius Satkauskas et al.
Journal of Drug Targeting, 2013, 21 (4), pp.407-414. ⟨10.3109/1061186X.2012.761223⟩
Article dans une revue inserm-02438654 v1

Irinotecan Delivery by Microbubble-Assisted Ultrasound: In Vitro Validation and a Pilot Preclinical Study

Jean-Michel Escoffre , Novell Anthony , Sophie Serriere , Thierry Lecomte , Ayache Bouakaz
Molecular Pharmaceutics, 2013, 10 (7), pp.2667-2675. ⟨10.1021/mp400081b⟩
Article dans une revue inserm-02438593 v1

Second Harmonic and Subharmonic for Non-Linear Wideband Contrast Imaging Using a Capacitive Micromachined Ultrasonic Transducer Array

Novell Anthony , Jean-Michel Escoffre , Ayache Bouakaz
Ultrasound in Medicine & Biology, 2013, 39 (8), pp.1500-1512. ⟨10.1016/j.ultrasmedbio.2013.03.002⟩
Article dans une revue inserm-02438581 v1

In-Vivo Gene Delivery by Sonoporation: Recent Progress and Prospects

Jean-Michel Escoffre , Aya Zeghimi , Novell Anthony , Ayache Bouakaz
Current Gene Therapy, 2013, 13 (1), pp.2-14. ⟨10.2174/156652313804806606⟩
Article dans une revue inserm-02438876 v1

Focused ultrasound mediated drug delivery from temperature-sensitive liposomes: in-vitro characterization and validation

Jean-Michel Escoffre , Novell Anthony , Mariska de Smet , Ayache Bouakaz
Physics in Medicine and Biology, 2013, 58 (22), pp.8135-8151. ⟨10.1088/0031-9155/58/22/8135⟩
Article dans une revue inserm-02438570 v1

Doxorubicin liposome-loaded microbubbles for contrast imaging and ultrasound-triggered drug delivery

Jean-Michel Escoffre , Christophoros Mannaris , Bart Geers , Anthony Novell , Ine Lentacker et al.
IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control, 2013, 60 (1), pp.78-87. ⟨10.1109/TUFFC.2013.2539⟩
Article dans une revue inserm-02438665 v1

New insights into uteroplacental perfusion: Quantitative analysis using Doppler and contrast-enhanced ultrasound imaging

Chloé Julie Arthuis , Novell Anthony , Jean-Michel Escoffre , Frédéric Patat , Ayache Bouakaz et al.
Placenta, 2013, 34 (5), pp.424-431. ⟨10.1016/j.placenta.2013.01.019⟩
Article dans une revue istex inserm-02438627 v1
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Electrochemotherapy: Progress and Prospects.

Jean-Michel Escoffre , Marie-Pierre Rols
Current Pharmaceutical Design, 2012, epub ahead of print
Article dans une revue inserm-00680356 v1
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Electrochemotherapy: Progress and Prospects

Jean-Michel Escoffre , Marie-Pierre Rols
Current Pharmaceutical Design, 2012, 18 (23), pp.3406-3415. ⟨10.2174/138161212801227087⟩
Article dans une revue inserm-02438896 v1
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Drug delivery by electropulsation: Recent developments in oncology

Teissié Justin , Jean-Michel Escoffre , Aurélie Paganin-Gioanni , Sophie Chabot , Elisabeth Bellard et al.
International Journal of Pharmaceutics, 2012, 423 (1), pp.3-6. ⟨10.1016/j.ijpharm.2011.09.038⟩
Article dans une revue inserm-02438916 v1

Destabilizing Giant Vesicles with Electric Fields: An Overview of Current Applications

Thomas Portet , Chloé Mauroy , Vincent Démery , Thibault Houles , Jean-Michel Escoffre et al.
Journal of Membrane Biology, 2012, 245 (9), pp.555-564. ⟨10.1007/s00232-012-9467-x⟩
Article dans une revue istex hal-00998473 v1

New Insights in the Gene Electrotransfer Process: Evidence for the Involvement of the Plasmid DNA Topology

Jean-Michel Escoffre , Biliana Nikolova , Laetitia Mallet , Julien Henri , Cyril Favard et al.
Current Gene Therapy, 2012, 12 (5), pp.417-422. ⟨10.2174/156652312802762554⟩
Article dans une revue inserm-02438890 v1

Hyaluronidase and Collagenase Increase the Transfection Efficiency of Gene Electrotransfer in Various Murine Tumors

Maja Cemazar , Muriel Golzio , Gregor Sersa , Jean-Michel Escoffre , Andrej Coer et al.
Human Gene Therapy, 2012, 23 (1), pp.128-137. ⟨10.1089/hum.2011.073⟩
Article dans une revue inserm-02438934 v1

Cholesterol implications in plasmid DNA electrotransfer: Evidence for the involvement of endocytotic pathways

Christelle Rosazza , Émilie Phez , Jean-Michel Escoffre , Laurence Cézanne , Andreas Zumbusch et al.
International Journal of Pharmaceutics, 2012, 423 (1), pp.134-143. ⟨10.1016/j.ijpharm.2011.05.024⟩
Article dans une revue inserm-02438956 v1

Doxorubicin Delivery into Tumor Cells with Ultrasound and Microbubbles

Jean-Michel Escoffre , Julien Piron , Novell Anthony , Ayache Bouakaz
Molecular Pharmaceutics, 2011, 8 (3), pp.799-806. ⟨10.1021/mp100397p⟩
Article dans une revue inserm-02438975 v1

The Actin Cytoskeleton Has an Active Role in the Electrotransfer of Plasmid DNA in Mammalian Cells

Christelle Rosazza , Jean-Michel Escoffre , Andreas Zumbusch , Marie-Pierre Rols
Molecular Therapy, 2011, 19 (5), pp.913-921. ⟨10.1038/mt.2010.303⟩
Article dans une revue inserm-02438983 v1
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Electromediated formation of DNA complexes with cell membranes and its consequences for gene delivery

Jean-Michel Escoffre , Thomas Portet , Cyril Favard , Justin Teissié , David S. Dean et al.
Biochimica et Biophysica Acta:Biomembranes, 2011, 1808 (6), pp.1538-1543. ⟨10.1016/j.bbamem.2010.10.009⟩
Article dans une revue hal-00998724 v1
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Direct visualization at the single-cell level of siRNA electrotransfer into cancer cells

Aurélie Paganin-Gioanni , Elisabeth Bellard , Jean-Michel Escoffre , Marie-Pierre Rols , Teissié Justin et al.
Proceedings of the National Academy of Sciences of the United States of America, 2011, 108 (26), pp.10443-10447. ⟨10.1073/pnas.1103519108⟩
Article dans une revue inserm-02438940 v1

Gene Transfer: How Can the Biological Barriers Be Overcome?

Jean-Michel Escoffre , Justin Teissié , Marie-Pierre Rols
Journal of Membrane Biology, 2010, 236 (1), pp.61-74. ⟨10.1007/s00232-010-9275-0⟩
Article dans une revue istex inserm-02439003 v1

Observations of the Mechanisms of Electromediated DNA Uptake - From Vesicles to Tissues

Muriel Golzio , Jean-Michel Escoffre , Thomas Portet , Chloé Mauroy , Justin Teissié et al.
Current Gene Therapy, 2010, 10 (4), pp.256-266. ⟨10.2174/156652310791823461⟩
Article dans une revue hal-00999322 v1

In Vitro Gene Transfer by Electrosonoporation

Jean-Michel Escoffre , Kadija Kaddur , Marie-Pierre Rols , Ayache Bouakaz
Ultrasound in Medicine & Biology, 2010, 36 (10), pp.1746-1755. ⟨10.1016/j.ultrasmedbio.2010.06.019⟩
Article dans une revue inserm-02438997 v1

Electro-mediated gene transfer and expression are controlled by the life-time of DNA/membrane complex formation

Cécile Faurie , Matej Reberšek , Muriel Golzio , Masa Kanduser , Jean-Michel Escoffre et al.
The Journal of Gene Medicine, 2010, 12 (1), pp.117-125. ⟨10.1002/jgm.1414⟩
Article dans une revue inserm-02439034 v1

What is (Still not) Known of the Mechanism by Which Electroporation Mediates Gene Transfer and Expression in Cells and Tissues

Jean-Michel Escoffre , Thomas Portet , Luc Wasungu , Teissié Justin , David S. Dean et al.
Molecular Biotechnology, 2009, 41 (3), pp.286-295. ⟨10.1007/s12033-008-9121-0⟩
Article dans une revue istex inserm-02439136 v1

Gene electrotransfer: from biophysical mechanisms to in vivo applications. Part 2 - In vivo developments and present clinical applications

Jean-Michel Escoffre , Chloé Mauroy , Thomas Portet , Luc Wasungu , Aurélie Paganin-Gioanni et al.
Biophysical Reviews and Letters, 2009, 1 (4), pp.185-191. ⟨10.1007/s12551-009-0019-2⟩
Article dans une revue inserm-02439026 v1

Transgene expression of transfected supercoiled plasmid DNA concatemers in mammalian cells

Jean-Michel Escoffre , Elisabeth Bellard , Muriel Golzio , Justin Teissié , Marie-Pierre Rols
The Journal of Gene Medicine, 2009, 11 (11), pp.1071-1073. ⟨10.1002/jgm.1384⟩
Article dans une revue istex inserm-02439039 v1

A 3D in vitro spheroid model as a way to study the mechanisms of electroporation

Luc Wasungu , Jean-Michel Escoffre , Annie Valette , Justin Teissié , Marie-Pierre Rols
International Journal of Pharmaceutics, 2009, 379 (2), pp.278-284. ⟨10.1016/j.ijpharm.2009.03.035⟩
Article dans une revue istex inserm-02439046 v1

Visualization of Membrane Loss during the Shrinkage of Giant Vesicles under Electropulsation

Thomas Portet , Franc Camps I Febrer , Jean-Michel Escoffre , Cyril Favard , Marie-Pierre Rols et al.
Biophysical Journal, 2009, 96 (10), pp.4109-4121. ⟨10.1016/j.bpj.2009.02.063⟩
Article dans une revue inserm-02439154 v1

Long-lasting In vivo Gene Silencing by Electrotransfer of shRNA Expressing Plasmid

Jean-Michel Escoffre , Arnaud Debin , Jean-Paul Reynes , Daniel Drocourt , Gérard Tiraby et al.
Technology in Cancer Research and Treatment, 2008, 7 (2), pp.109-116. ⟨10.1177/153303460800700203⟩
Article dans une revue inserm-02439064 v1

Membrane perturbation by an external electric field: a mechanism to permit molecular uptake

Jean-Michel Escoffre , David S. Dean , Marie Hubert , Marie-Pierre Rols , Cyril Favard
European Biophysics Journal, 2007, 36 (8), pp.973-983. ⟨10.1007/s00249-007-0194-7⟩
Article dans une revue istex inserm-02439124 v1

In vivo imaging of tumor growth after electrochemotherapy with cisplatin

Maja Cemazar , Muriel Golzio , Jean-Michel Escoffre , Bettina Couderc , Gregor Sersa et al.
Biochemical and Biophysical Research Communications, 2006, 348 (3), pp.997-1002. ⟨10.1016/j.bbrc.2006.07.132⟩
Article dans une revue istex inserm-02439075 v1
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Irinotecan delivery by microbubble-assisted ultrasound - A pilot preclinical study

Jean-Michel Escoffre , Anthony Novell , Sophie Serrière , Ayache Bouakaz
12th International Symposium on Therapeutic Ultrasound, Jun 2012, Heidelberg (Germany), Germany. pp.40-45, ⟨10.1063/1.4769914⟩
Communication dans un congrès hal-04280331 v1
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Analysis of Contrast-Enhanced Ultrasound using fluid dynamic

Baudouin Denis de Senneville , Anthony Novell , Chloé J. Arthuis , Vanda Mendes , Paul-Armand Dujardin et al.
IEEE International Symposium on Biomedical Imaging (ISBI), Apr 2018, Washington, United States
Communication dans un congrès hal-01963092 v1

A fluid dynamic model for quantitative contrast-enhanced ultrasound imaging: validation for the assessment of uteroplacental perfusion

Baudouin Denis de Senneville , Anthony Novell , Chloé J. Arthuis , Vanda Mendes , Paul-Armand Dujardin et al.
IEEE International Ultrasonics Symposium, Oct 2018, Kobe, Japan
Communication dans un congrès hal-01963238 v1
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Involvement of cytoskeleton in sonoporation and drug delivery

Aya Zeghimi , Jean-Michel Escoffre , Ayache Bouakaz
2014 IEEE International Ultrasonics Symposium, Sep 2014, Chicago (IL), United States. pp.850-853, ⟨10.1109/ultsym.2014.0209⟩
Communication dans un congrès hal-04280322 v1
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Lattice of nonlinear coupled oscillators: An acousto-mechanical analogy of gas microbubble

Jennifer Chaline , Ayache Bouakaz , Jean-Michel Escoffre , Victor Sanchez-Morcillo , Noe Jimenez et al.
2014 IEEE International Ultrasonics Symposium, Sep 2014, Chicago (IL), United States. pp.2277-2279, ⟨10.1109/ultsym.2014.0567⟩
Communication dans un congrès hal-04280323 v1
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Ultrastructural sonoporation bio-effects: Comparative study on two human cancer cell lines

Aya Zeghimi , Jean-Michel Escoffre , Ayache Bouakaz
2013 IEEE International Ultrasonics Symposium (IUS), Jul 2013, Prague, Czech Republic. pp.61-64, ⟨10.1109/ultsym.2013.0016⟩
Communication dans un congrès hal-04280326 v1
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Role of thermal and mechanical effects on drug release from thermosensitive nanocarriers

Anthony Novell , Jean-Michel Escoffre , Chantal Al-Sabbagh , Christophoros Mannaris , Elias Fattal et al.
2012 IEEE International Ultrasonics Symposium, Oct 2012, Dresden (GERMANY), Germany. pp.1873-1876, ⟨10.1109/ultsym.2012.0470⟩
Communication dans un congrès hal-04280329 v1
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High-intensity focused ultrasound-mediated doxorubicin delivery with thermosensitive liposomes

Jean-Michel Escoffre , Christophoros Mannaris , Anthony Novell , Laëtitia Rioc , Marie-Edith Meyre et al.
11TH INTERNATIONAL SYMPOSIUM ON THERAPEUTIC ULTRASOUND, Apr 2011, New York, NY, United States. pp.81-87, ⟨10.1063/1.4757315⟩
Communication dans un congrès hal-04280336 v1
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Doxorubicin-liposomes loaded microbubbles for ultrasound-triggered doxorubicin delivery

Jean-Michel Escoffre , Anthony Novell , Bart Geers , Ine Lentacker , Ayache Bouakaz
Acoustics 2012, Apr 2012, Nantes, France
Communication dans un congrès hal-00810695 v1
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Blood-brain barrier disruption with focused ultrasound enhances delivery of dopamine transporter tracer (PE2I) into the brain

Jean-Michel Escoffre , Sophie Serrière , Sylvie Bodard , Anthony Novell , Sylvie Chalon et al.
Acoustics 2012, Apr 2012, Nantes, France
Communication dans un congrès hal-00810925 v1
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Ultrastructural modifications of cell membranes and organelles induced by sonoporation

Aya Zeghimi , Rustem Uzbekov , Brigite Arbeille , Jean-Michel Escoffre , Ayache Bouakaz
2012 IEEE International Ultrasonics Symposium (IUS), Oct 2012, Dresden (Germany), Germany. pp.2045-2048, ⟨10.1109/ultsym.2012.0511⟩
Communication dans un congrès hal-04280327 v1
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Enhanced gene transfection using ultrasound and Vevo Micromarker ® microbubbles

Julien Piron , Jean-Michel Escoffre , Kadija Kaddur , Anthony Novell , Ayache Bouakaz
2010 IEEE International Ultrasonics Symposium, Oct 2010, San Diego, United States. ⟨10.1109/ULTSYM.2010.5935896⟩
Communication dans un congrès hal-04280337 v1

Dynamic of DNA/membrane interaction after electrotransfection process.

J.M. Escoffre , E. Phez , C. Favard , J. Teissié , M.P. Rols
XIIIth Meeting of Study Group of Molecules – Membranes Interactions, 2008, Strasbourg, France
Communication dans un congrès hal-00455675 v1

DNA electrotransfection: effects of electric fields on cell membrane

J.M. Escoffre , E. Phez , L. Cézanne , F. Camps , David S. Dean et al.
XIXth International Symposium of BioElectrochemistry Society, 2007, Toulouse, France
Communication dans un congrès hal-00455681 v1
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In vivo imaging of siRNA electrotransfer and silencing in different organs

Aurélie Paganin-Gioanni , Jean-Michel Escoffre , Laurent Mazzolini , Marie-Pierre Rols , Justin Teissie et al.
11th Mediterranean Conference on Medical and Biological Engineering and Computing 2007, Jun 2007, Ljubljana, Slovenia
Communication dans un congrès hal-04280340 v1

New insights on mechanisms of electrogenetransfer

J.M. Escoffre , E. Phez , F. Camps , Thomas Portet , David S. Dean et al.
XXIIth Scientific days of Thematic Group of Research on Vectorisation., 2007, Strasbourg, France
Communication dans un congrès hal-00455678 v1

DNA electrotransfection: Electric field effects on cell membrane

J.M. Escoffre , E. Phez , L. Cézanne , F. Camps , David S. Dean et al.
VIth National Congress of Francophone Society of Cell and Gene Therapy, 2007, Giens, France
Communication dans un congrès hal-00455679 v1

DNA/membrane interaction: a key step of electrotransfection

J.M. Escoffre , E. Phez , F. Camps , C. Favard , J. Teissié et al.
VIth European Biophysics Congress, 2006, London, United Kingdom
Communication dans un congrès hal-00455676 v1