
Jean-Jacques HELESBEUX
91
Documents
Publications
Publications
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30th Annual GP2A Medicinal Chemistry ConferencePharmaceuticals, 16 (3), pp.432, 2023, ⟨10.3390/ph16030432⟩
Proceedings/Recueil des communications
hal-04214224
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29th Annual GP2A Medicinal Chemistry Conference29th Annual GP2A Medicinal Chemistry Conference, Pharmaceuticals, 14 (12), pp.1278, 2021, ⟨10.3390/ph14121278⟩
Proceedings/Recueil des communications
hal-03969961
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29th Annual GP2A Medicinal Chemistry ConferencePharmaceuticals, 14 (12), pp.1278, 2021, ⟨10.3390/ph14121278⟩
N°spécial de revue/special issue
hal-03788190
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Potentiating agents for protecting plants from fungal infectionsFrance, Patent n° : US 20200002717 A1 20200102. 2020
Brevet
hal-02866536
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Preparation of tocotrienol derivatives, pharmaceutical composition and method of use in 5-lipoxygenase related diseasesFrance, Patent n° : WO 2017032881 A1 20170302. 2017
Brevet
hal-02866630
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Potentiating agents for protecting plants from fungal infectionsFrance, Patent n° : US 20150216174 A1 20150806. 2015
Brevet
hal-02866739
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Anti-inflammatory activity of vitamin E derivativesJournée Des Doctorants de l’ED EGAAL, Jul 2019, Rennes, France
Communication dans un congrès
hal-02795186
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Structure-based modeling, semisynthesis and biological evaluations of garcinoic acid derivativesJournée Des Doctorants de la SFR QUASAV, Oct 2019, Angers, France
Communication dans un congrès
hal-02794835
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Molecular docking, semisynthesis and biological evaluations of garcinoic acid amides as 5-lipoxygenase inhibitors27th Annual GP2A Medicinal Chemistry Conference, Aug 2019, Nottingham, United Kingdom. pp.179, ⟨10.3390/ph12040179⟩
Communication dans un congrès
hal-02794994
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Aldaulactone, a new phytotoxin involved in Alternaria dauci–Daucus carota interaction11th International Congress of Plant Pathology, 2018, Boston, United States
Communication dans un congrès
hal-02516643
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Design, semisynthesis and biological evaluations of garcinoic acid derivatives as novel anti-inflammatory agents25th Young Research Fellows Meeting, Mar 2018, Orléans, France
Communication dans un congrès
hal-02796904
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Hémisynthèse d’analogues originaux de la vitamine E à visée anti-inflammatoireJournée des doctorants de la SFR QUASAV, 10e édition, Oct 2017, Angers, France
Communication dans un congrès
hal-02864455
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Towards pharmacologically active tocotrienol derivatives starting from δ-garcinoic acid as a common natural precursor24th Young Research Fellow’s Meeting, Feb 2017, Châtenay-Malabry, France
Communication dans un congrès
hal-02864430
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Semisynthetic pathways starting from δ-garcinoic acid towards anti-inflammatory tocotrienols isolated from New Caledonian endemic plants5th AFERP International Conference "Pharmacognosy from here and there", Jul 2017, Angers, France
Communication dans un congrès
hal-02864451
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Towards an Alternative to NSAIDs Based on Vitamin E Analogues25th Conference of GP2A, Aug 2017, Liverpool, United Kingdom. pp.97, ⟨10.3390/ph10040097⟩
Communication dans un congrès
hal-02797756
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Influence of fungal exudates of Alternaria dauci on carrot partial resistanceInternational Symposium on Carrot and Other Apiaceae, International Society for Horticultural Science (ISHS). INT., 2017, Angers, France. pp.231-236, ⟨10.17660/ActaHortic.2017.1153.34⟩
Communication dans un congrès
hal-02516581
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Resistance and pathogenicity: how toxins are involved in the carrot-Alternaria dauci interaction10ème édition des doctorants de la SFR Quasav, 2017, Angers, France
Communication dans un congrès
hal-02516577
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Hémisynthèse de nouveaux analogues de la vitamine E à visée anti-inflammatoireSéminaire recherche du département Pharmacie, Faculté de Santé, Université d’Angers, Sep 2016, Angers, France
Communication dans un congrès
hal-02864459
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Lien entre agressivité et composition des exsudats chez Alternaria dauci, agent causal de la brûlure foliaire de la carotte11èmes Rencontres Phytopathologie-Mycologie, 2016, Aussois, France
Communication dans un congrès
hal-02516455
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Signaling pathways activated after exposure to phytoalexins: an Achilles'heel for necrotrophic fungi?Mission possible: food for all through appropriate plant protection. XVIII International Plant Protection Congress, 2015, Berlin, Germany
Communication dans un congrès
hal-02516454
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Paradoxical effects of the topoisomerase inhibitor ethoxidine in the cellular processes leading to angiogenesis on endothelial cellsPrintemps de la Cardiologie : Recherche Fondamentale et Clinique, 2010, Nantes, France
Communication dans un congrès
hal-03247634
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From Phloridzin towards Semisynthetic Bioactive Dihydrochalcones27th Annual GP2A Medicinal Chemistry Conference, Aug 2019, Notthingham, United Kingdom. Pharmaceuticals, 12 (4), pp.179, 2019, ⟨10.3390/ph12040179⟩
Poster de conférence
hal-02798004
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The vitamin E derivative α-amplexichromanol as anti-inflammatory lead inspired from traditional african medicine67th Annual Conference of the Society for Medicinal Plant and Natural Product Research, Sep 2019, Innsbruck, Austria
Poster de conférence
hal-02864518
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SEMISYNTHESIS OF BIOACTIVE C-BENZYLATED DIHYDROCHALCONES FROM RENEWABLE SOURCESRICT 2019 - Interfacing Chemical Biology and Drug Discovery - 55th International Conference on Medicinal Chemistry, Jul 2019, Nantes, France
Poster de conférence
hal-02798163
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Computational Investigation of multi-target effects in the arachidonic acid cascade on the example of potent natural 5-LO inhibitor garcinoic acid67th Annual Conference of the Society for Medicinal Plant and Natural Product Research, Sep 2019, Innsbruck, Austria
Poster de conférence
hal-02864513
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Anti-inflammatory activity of w-oxidized tocotrienols26th Young Research Fellows Meeting, Feb 2019, Paris, France
Poster de conférence
hal-02796842
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Semisynthetic pathways towards anti-inflammatory tocotrienols isolated from new-caledonian endemic plants14a. RIIPN (14a Reunión Internacional de Productos Naturales), May 2018, Cuernavaca Morelos, Mexico
Poster de conférence
hal-02864440
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Omega-oxidized terpenoids: from traditional African medicine to novel insights into human vitamin physiology24th Conference on Isoprenoids, Sep 2018, Bialystok, Poland
Poster de conférence
hal-02864499
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Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase7th European Workshop on Lipid Mediators, Sep 2018, Bruxelles, Belgium
Poster de conférence
hal-02864504
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Semisynthesis of δ-(R)-tocotrienols8ème Symposium Francophone de Synthèse Totale, May 2018, Bordeaux, France
Poster de conférence
hal-02797021
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Semisynthetic pathways starting from δ-garcinoic acid towards anti-inflammatory tocotrienols isolated from New Caledonian endemic plantsJournées des doctorants de la SFR QUASAV, 11ème édition, Oct 2018, Angers, France
Poster de conférence
hal-02864443
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Computational binding mode prediction of ω-oxidized tocotrienols as inhibitors of 5-lipoxygenasePhyto-Valley 1st Austrian Summit on Natural Products, Jan 2018, Seefeld, Austria
Poster de conférence
hal-02864486
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Computational analysis of the interaction between vitamin E derivatives and 5-lipoxygenaseParacelsus Science Get Together, Jun 2018, Salzbourg, Austria
Poster de conférence
hal-02864497
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Semi-synthetic derivatives and endogenous metabolites of vitamin E as potent, selective and orally available inhibitors of 5 lipoxygenaseFrontiers in Medicinal Chemistry, Mar 2018, Iéna, Germany
Poster de conférence
hal-02864495
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α-amplexichromanol, a vitamin E semisynthetic analog – Valorization of its anti-inflammatory potentialJournée thématique de la SFR ICAT4208, May 2018, Angers, France
Poster de conférence
hal-02864434
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Synthèse et évaluation biologique de nouveaux actifs potentiels ciblant les dysfonctionnements mitochondriauxJournée thématique de la SFR ICAT, May 2018, Angers, France
Poster de conférence
hal-02797199
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26th Annual GP2A Medicinal Chemistry Conference & 32nd Journées Franco-Belges de PharmacochimieJoint 26th GP2A/ 32nd JFB Conferences, Jun 2018, Asnelles sur Mer, France. MDPI, Pharmaceuticals, 12 (2), pp.73, 2019, ⟨10.3390/ph12020073⟩
Poster de conférence
hal-02796872
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Garcinia species are potent and selective, allosteric inhibitors of 5-lipoxygenase and provide novel insights into human vitamin E physiologyPhyto-Valley 1st Austrian Summit on Natural Products, Jan 2018, Seefeld, Austria
Poster de conférence
hal-02864490
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Semisynthetics Pathways Starting from δ-Garcinoic Acid towards Anti-Inflammatory Tocotrienols Isolated from New-Caledonian Endemic Plants25th Conference of GP2A, Aug 2017, Liverpool, United Kingdom. Pharmaceuticals, 10 (4), pp.97, 2017, ⟨10.3390/ph10040097⟩
Poster de conférence
hal-02797913
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Extraction and Purification of δ-Tocotrienol from Bixa orellana and Semi-Synthesis of 7-Formyl-δ-tocotrienol25th Conference of GP2A, Aug 2017, Liverpool, United Kingdom. Pharmaceuticals, 10 (4), pp.97, 2017, ⟨10.3390/ph10040097⟩
Poster de conférence
hal-02797856
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δ-garcinoic acid, a platform to tocotrienol derivatives isolated from barks of New Caledonian endemics plants5e journées scientifiques de l’école doctorale VENAM, Nov 2016, Nantes, France
Poster de conférence
hal-02864424
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mPGES-1 as a New Target for Garcinoic Acid IsoformsThe 24th Conference” of the Groupement des Pharmacochimistes de l’Arc Atlantique (GP2A), Aug 2016, Angers, France. Pharmaceuticals, 10 (1), pp.17, 2017, ⟨10.3390/ph10010017⟩
Poster de conférence
hal-02797636
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δ-Garcinoic Acid, a Convenient Natural Precursor to the Attractive δ-TocotrienolThe 24th Conference” of the Groupement des Pharmacochimistes de l’Arc Atlantique (GP2A), Aug 2016, Angers, France. Pharmaceuticals, 10 (1), pp.17, 2017, ⟨10.3390/ph10010017⟩
Poster de conférence
hal-02797528
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Synthetic 3-deoxyanthocyanidin analogues of delphinidin as potential vasorelaxant agents23rd Conference of the Groupement des Pharmacochimistes de l’Arc Atlantique (GP2A), Aug 2015, Munster, Germany. Pharmaceuticals, 9 (1), pp.1, 2016, ⟨10.3390/ph9010001⟩
Poster de conférence
hal-02864383
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Semisynthesis of natural formylated tocotrienols23rd Conference of the Groupement des Pharmacochimistes de l’Arc Atlantique (GP2A), Aug 2015, Munster, Germany. Pharmaceuticals, 9 (1), pp.1, 2016, ⟨10.3390/ph9010001⟩
Poster de conférence
hal-02864395
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Lien entre résistance partielle à Alternaria dauci et résistance aux toxines fongiques chez la carotte10èmes Rencontres de Phytopathologie- Mycologie, 2014, Aussois, France. 2014
Poster de conférence
hal-03281870
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Semisynthetic modifications of δ-amplexichromanol, an original tocotrienol with antitumoral properties22èmes Conférences Européennes du Groupement des Pharmacochimistes de l’Arc Atlantique (GP2A), 2014, Nantes, France. 2014
Poster de conférence
hal-03247967
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Studies of the reactivity of 2,3-alkoxynaphtoic acids in the presence of organometallic nucleophiles20èmes Conférences Européennes du Groupement des Pharmacochimistes de l’Arc Atlantique (GP2A), 2011, Cork, Ireland. 2011
Poster de conférence
hal-03247975
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New self-assembled monolayers for DIAMS mass spectrometry"titre manquant", 2009, Dublin, Ireland. 2009
Poster de conférence
hal-03247633
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“The 24th Conference” of the Groupement des Pharmacochimistes de l’Arc Atlantique (GP2A)2017, pp.17. ⟨10.3390/ph10010017⟩
Autre publication scientifique
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