Karine Adel-Patient

Directrice de Recherche INRAE Université Paris-Saclay, CEA, INRAE Unité Médicaments et Technologies pour la Santé DRF/Institut Joliot/MTS/SPI/Laboratoire d'ImmunoAllergie Alimentaire
65%
Libre accès
113
Documents
Affiliations actuelles
  • Médicaments et Technologies pour la Santé (MTS)
  • Service de Pharmacologie et Immunoanalyse (SPI)
  • Laboratoire d'immuno-allergie alimentaire (LI2A)
  • Département Alimentation Humaine - INRAE (ALIM-H)
Identifiants chercheurs
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Publications

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Publications

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Dietary exposure to mixtures of chemicals in the first year of life and allergic and respiratory diseases up to 8 years in the French EDEN mother-child cohort

Manel Ghozal , Rosalie Delvert , Karine Adel-Patient , Muriel Tafflet , Isabella Annesi‐maesano et al.
Food and Chemical Toxicology, 2025, 196, pp.115167. ⟨10.1016/j.fct.2024.115167⟩
Article dans une revue anses-04964046 v1
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Prenatal exposure to heavy metals and childhood atopic disease

Courtney Dow , Manik Kadawathagedara , Manel Ghozal , Marie-Aline Charles , Karine Adel-Patient et al.
Environmental Research, 2025, 270, pp.121062. ⟨10.1016/j.envres.2025.121062⟩
Article dans une revue inserm-05074647 v1

Long-term exposure from perinatal life to food-grade TiO$_2$ alters intestinal homeostasis and predisposes to food allergy in young mice

Mohammad Issa , Chloé Michaudel , Marine Guinot , Marta Grauso , Blanche Guillon et al.
Allergy, 2024, 79 (2), pp.471-484. ⟨10.1111/all.15960⟩
Article dans une revue hal-04334514 v1
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Identification of Gut Biomarkers of FPIES in a Longitudinal Comparative Pediatric Study

Anais Lemoine , N Kapel , I Nicolis , P Tounian , A Bruneau et al.
Article dans une revue hal-04923891 v1
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Characteristics of infant formula consumed in the first months of life and allergy in the EDEN mother-child cohort

Moufidath Adjibade , Lucille Vigneron , Rosalie Delvert , Karine Adel-Patient , Amandine Divaret-Chauveau et al.
Maternal and Child Nutrition, 2024, 20 (4), pp.e13673. ⟨10.1111/mcn.13673⟩
Article dans une revue hal-04626780 v1
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Maternal diet quality during pregnancy and biomarkers of potentially toxic trace element exposure: Data from the ELFE cohort

Courtney Dow , Manik Kadawathagedara , Manel Ghozal , Marie-Aline Charles , Karine Adel-Patient et al.
Food and Chemical Toxicology, 2024, 190, pp.114793. ⟨10.1016/j.fct.2024.114793⟩
Article dans une revue hal-04664061 v1
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Prenatal dietary exposure to mixtures of chemicals is associated with allergy or respiratory diseases in children in the ELFE nationwide cohort

Manel Ghozal , Manik Kadawathagedara , Rosalie Delvert , Amandine Divaret-Chauveau , Chantal Raherison et al.
Environmental Health, 2024, 23 (1), pp.5. ⟨10.1186/s12940-023-01046-y⟩
Article dans une revue anses-04426377 v1

Sunflower seed allergy: Identification of novel 2S‐albumins as potential marker allergens

J. Achour , M. Reche , T. Valbuena , C. Chapuis , B. Guillon et al.
Allergy, In press, ⟨10.1111/all.16124⟩
Article dans une revue hal-04564636 v1
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Identification of the major immune differences in severe asthmatic children according to their atopic dermatitis status

Guillaume Lezmi , Clément Poirault , Marta Grauso , Céline Dietrich , Karine Adel-Patient et al.
Cellular Immunology, 2024, 397-398, pp.104815. ⟨10.1016/j.cellimm.2024.104815⟩
Article dans une revue hal-04491593 v1
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Maternal diet quality with child allergic and respiratory multimorbidity in the Elfe birth cohort

Rosalie Delvert , Marie Aline Charles , Bénédicte Leynaert , Manik Kadawathagedara , Karine Adel-Patient et al.
Scientific Reports, 2024, 14 (1), pp.13048. ⟨10.1038/s41598-024-63456-3⟩
Article dans une revue hal-04616765 v1
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Optimization of a sample preparation workflow based on UHPLC-MS/MS method for multi-allergen detection in chocolate: An outcome of the ThRAll project

Jean Henrottin , Rosa Pilolli , Anne-Catherine Huet , Christof van Poucke , Chiara Nitride et al.
Food Control, 2023, 143, pp.109256. ⟨10.1016/j.foodcont.2022.109256⟩
Article dans une revue hal-03761018 v1
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Pre-, pro-, syn-, and Postbiotics in Infant Formulas: What Are the Immune Benefits for Infants?

Anaïs Lemoine , Patrick Tounian , Karine Adel-Patient , Muriel Thomas
Nutrients, 2023, 15, ⟨10.3390/nu15051231⟩
Article dans une revue hal-04012865 v1
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Maternal Diet Quality during Pregnancy and Allergic and Respiratory Multimorbidity Clusters in Children from the EDEN Mother–Child Cohort

Rosalie Delvert , Manel Ghozal , Karine Adel-Patient , Manik Kadawathagedara , Barbara Heude et al.
Nutrients, 2023, 15 (1), pp.146. ⟨10.3390/nu15010146⟩
Article dans une revue hal-03949617 v1
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Assessment of local and systemic signature of eosinophilic esophagitis (EoE) in children through multi-omics approaches

Karine Adel-Patient , Florence Campeotto , Marta Grauso , Blanche Guillon , Marco Moroldo et al.
Frontiers in Immunology, 2023, 14, pp.1108895. ⟨10.3389/fimmu.2023.1108895⟩
Article dans une revue hal-04032831 v1
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Complementary feeding practices are related to the risk of food allergy in the ELFE cohort

T. Adam , A Divaret‐chauveau , C. Roduit , Karine Adel-Patient , A. Deschildre et al.
Allergy, 2023, 79 (9), pp.2456-2466. ⟨10.1111/all.15828⟩
Article dans une revue hal-04174304 v1
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Prenatal dietary exposure to chemicals and allergy or respiratory diseases in children in the EDEN mother–child cohort

Manel Ghozal , Manik Kadawathagedara , Rosalie Delvert , Karine Adel-Patient , Muriel Tafflet et al.
Environment International, 2023, 180, pp.108195. ⟨10.1016/j.envint.2023.108195⟩
Article dans une revue hal-04229520 v1
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The Human Meconium Metabolome and Its Evolution during the First Days of Life

Nihel Bekhti , Florence Castelli , Alain Paris , Blanche Guillon , Christophe Junot et al.
Metabolites, 2022, 12 (5), pp.414. ⟨10.3390/metabo12050414⟩
Article dans une revue hal-04008723 v1

Development of incurred chocolate bars and broth powder with six fully characterised food allergens as test materials for food allergen analysis

Anne-Catherine Huet , Melody Paulus , Jean Henrottin , Chantal Brossard , Olivier Tranquet et al.
Analytical and Bioanalytical Chemistry, 2022, 414 (8), pp.2553-2570. ⟨10.1007/s00216-022-03912-z⟩
Article dans une revue hal-03630067 v1
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Enrichment of Formula in Probiotics or Prebiotics and Risk of Infection and Allergic Diseases up to Age 5.5 Years in the Nationwide Etude Longitudinale Française depuis l'Enfance (ELFE) Cohort

Moufidath Adjibade , Camille Davisse-Paturet , Amandine Divaret-Chauveau , Karine Adel-Patient , Chantal Raherison et al.
Journal of Nutrition, Health & Aging, 2022, 152 (4), pp.1138-1148. ⟨10.1093/jn/nxac013⟩
Article dans une revue hal-03694295 v1
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Prevalence of Food Allergy in France up to 5.5 Years of Age: Results from the ELFE Cohort

Sarah Tamazouzt , Karine Adel-Patient , Antoine Deschildre , Caroline Roduit , Marie Aline Charles et al.
Nutrients, 2022, 14 (17), pp.3624. ⟨10.3390/nu14173624⟩
Article dans une revue hal-03786831 v1
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Role of dietary fiber in promoting immune health—An EAACI position paper

Carina Venter , Rosan Meyer , Matthew Greenhawt , Isabella Pali-Schöll , Bright Nwaru et al.
Allergy, 2022, 77 (11), pp.3185-3198. ⟨10.1111/all.15430⟩
Article dans une revue hal-04009145 v1
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Perinatal exposure to foodborne inorganic nanoparticles: A role in the susceptibility to food allergy?

Mohammad Issa , Gilles Rivière , Eric Houdeau , Karine Adel-Patient
Frontiers in Allergy, 2022, 3 (1067281), ⟨10.3389/falgy.2022.1067281⟩
Article dans une revue hal-03902955 v1
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Immunodominant conformational and linear IgE epitopes lie in a single segment of Ara h 2

Stéphane Hazebrouck , Sarita Patil , Blanche Guillon , Nicole Lahood , Stephen Dreskin et al.
Journal of Allergy and Clinical Immunology, 2022, 150 (1), pp.131-139. ⟨10.1016/j.jaci.2021.12.796⟩
Article dans une revue hal-03889685 v1
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Rapid structural characterization of human milk oligosaccharides and distinction of their isomers using trapped ion mobility spectrometry time‐of‐flight mass spectrometry

Estelle Rathahao-Paris , Aurélie Delvaux , Meijie Li , Blanche Guillon , Eric Venot et al.
Journal of Mass Spectrometry, 2022, 57 (10), 7 p. ⟨10.1002/JMS.4885⟩
Article dans une revue hal-03940699 v1

Discovery based high resolution MS/MS analysis for selection of allergen markers in chocolate and broth powder matrices

Rosa Pilolli , Christof van Poucke , Elisabetta de Angelis , Chiara Nitride , Marc de Loose et al.
Food Chemistry, 2021, 343, pp.128533. ⟨10.1016/j.foodchem.2020.128533⟩
Article dans une revue hal-03153322 v1
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A Comprehensive Analysis of Immune Constituents in Blood and Bronchoalveolar Lavage Allows Identification of an Immune Signature of Severe Asthma in Children

Karine Adel-Patient , Marta Grauso , Rola Abou-Taam , Blanche Guillon , Céline Dietrich et al.
Frontiers in Immunology, 2021, 12, pp.1071-1077. ⟨10.3389/fimmu.2021.700521⟩
Article dans une revue hal-03327837 v1
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Sensitization Potency of Sunflower Seed Protein in a Mouse Model: Identification of 2S‐Albumins More Allergenic Than SFA‐8

Jihana Achour , Marine Guinot , Blanche Guillon , Romain Kapel , Olivier Galet et al.
Molecular Nutrition and Food Research, 2021, 65 (18), ⟨10.1002/mnfr.202100369⟩
Article dans une revue hal-03322664 v1
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Trapped ion mobility spectrometry time-of-flight mass spectrometry for high throughput and high resolution characterization of human milk oligosaccharide isomers

Aurélie Delvaux , Estelle Rathahao-Paris , Blanche Guillon , Sophie Cholet , Karine Adel-Patient et al.
Analytica Chimica Acta, 2021, 1180, pp.338878. ⟨10.1016/j.aca.2021.338878⟩
Article dans une revue hal-03533998 v1
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Allergen risk assessment for specific allergy to small ruminant's milk: development of sensitive immunoassays to detect goat's and sheep's milk contaminations in dairy food matrices

Hervé Bernard , Stéphane Hazebrouck , Nicolas Gaiani , Karine Adel-Patient
Frontiers in Allergy, 2021, 2 (733875), ⟨10.3389/falgy.2021.733875⟩
Article dans une revue hal-03889673 v1
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Organic food consumption during the complementary feeding period and respiratory or allergic diseases up to age 5.5 years in the ELFE cohort

David Payet , Moufidath Adjibade , Julia Baudry , Manel Ghozal , Aurore Camier et al.
Frontiers in Nutrition, 2021, 8, pp.791430. ⟨10.3389/fnut.2021.791430⟩
Article dans une revue hal-03525019 v1
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Enrichment of infant formula with long-chain polyunsaturated fatty acids and risk of infection and allergy in the nationwide ELFE birth cohort

Moufidath Adjibade , Camille Davisse-Paturet , Jonathan Y Bernard , Karine Adel-Patient , Amandine Divaret-Chauveau et al.
Allergy, 2021, 77 (5), pp.1522-1533. ⟨10.1111/all.15137⟩
Article dans une revue hal-03693984 v1

Observational Study of Chlorpromazine in Hospitalized Patients with COVID-19

Karine Adel-Patient , Marta Grauso , Rola Abou-Taam , Blanche Guillon , Céline Dietrich et al.
Clinical Drug Investigation, 2021, 41 (3), pp.221-233. ⟨10.1007/s40261-021-01001-0⟩
Article dans une revue hal-04360161 v1
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Immune signatures distinguish frequent from non-frequent exacerbators among children with severe asthma

Karine Adel-Patient , Marta Grauso , Rola Abou Taam , Blanche Guillon , Céline Dietrich et al.
Allergy, 2021, 76 (7), pp.2261-2264. ⟨10.1111/all.14759⟩
Article dans une revue hal-03133856 v1
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Breastfeeding initiation or duration and longitudinal patterns of infections up to 2 years and skin rash and respiratory symptoms up to 8 years in the EDEN mother–child cohort

Camille Davisse-Paturet , Karine Adel-Patient , Anne Forhan , Sandrine Lioret , Isabella Annesi‐maesano et al.
Maternal and Child Nutrition, 2020, 16 (3), ⟨10.1111/mcn.12935⟩
Article dans une revue hal-02904859 v1

Immunological Outcomes of Allergen-Specific Immunotherapy in Food Allergy

Ann-Marie Malby Schoos , Dominique Bullens , Bo Lund Chawes , Joana Costa , Liselot de Vlieger et al.
Frontiers in Immunology, 2020, 11, ⟨10.3389/fimmu.2020.568598⟩
Article dans une revue (article de synthèse) hal-03349171 v1
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Circulating Ara h 6 as a marker of peanut protein absorption in tolerant and allergic humans following ingestion of peanut‐containing foods

Hervé Bernard , Paul J Turner , Sandrine Ah‐leung , Monica Ruiz‐garcia , Elizabeth Naomi Clare Mills et al.
Clinical and Experimental Allergy, 2020, 50 (9), pp.1093-1102. ⟨10.1111/cea.13706⟩
Article dans une revue hal-03349239 v1

The Effect of the Food Matrix on the In Vitro Bio‐Accessibility and IgE Reactivity of Peanut Allergens

Huan Rao , Ivona Baricevic , Hervé Bernard , Frances Smith , Rebekah Sayers et al.
Molecular Nutrition and Food Research, 2020, 64 (14), pp.1-9. ⟨10.1002/mnfr.201901093⟩
Article dans une revue hal-03349630 v1
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Basal Ti Level in the human placenta and meconium and evidence of a materno-foetal transfer of food-grade TiO2 nanoparticles in an ex vivo placental perfusion model

Adèle Guillard , Eric Gaultier , Christel Cartier , Laurent Devoille , Johanna Noireaux et al.
Particle and Fibre Toxicology, 2020, 17 (1), ⟨10.1186/s12989-020-00381-z⟩
Article dans une revue hal-02945928 v2
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Critical review on proteotypic peptide marker tracing for six allergenic ingredients in incurred foods by mass spectrometry

Rosa Pilolli , Chiara Nitride , Nathalie Gillard , Anne-Catherine Huet , Christof van Poucke et al.
Food Research International, 2020, 128, pp.108747. ⟨10.1016/j.foodres.2019.108747⟩
Article dans une revue hal-02410519 v1
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Administration of Extensive Hydrolysates From Caseins and Lactobacillus rhamnosus GG Probiotic Does Not Prevent Cow’s Milk Proteins Allergy in a Mouse Model

Karine Adel-Patient , Marine Guinot , Blanche Guillon , Hervé Bernard , Amina Chikhi et al.
Frontiers in Immunology, 2020, 11, ⟨10.3389/fimmu.2020.01700⟩
Article dans une revue hal-03346706 v1
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Reply to J. Heinrich

Camille Davisse‐paturet , Chantal Raherison , Karine Adel-Patient , Amandine Divaret-Chauveau , Marie‐noëlle Dufourg et al.
Pediatric Allergy and Immunology, 2020, 31 (1), pp.108-109. ⟨10.1111/pai.13146⟩
Article dans une revue hal-02898234 v1
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Prevention of Allergy to a Major Cow's Milk Allergen by Breastfeeding in Mice Depends on Maternal Immune Status and Oral Exposure During Lactation

Karine Adel-Patient , Hervé Bernard , François Fenaille , Stéphane Hazebrouck , Christophe Junot et al.
Frontiers in Immunology, 2020, 11, ⟨10.3389/fimmu.2020.01545⟩
Article dans une revue hal-03321788 v1
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Detection and quantification of allergens in foods and minimum eliciting doses in food-allergic individuals (Thrall)

E.N. Clare Mills , Karine Adel-Patient , Hervé Bernard , Marc de Loose , Nathalie Gillard et al.
Journal of AOAC INTERNATIONAL, 2019, 102 (5), pp.1346-1353. ⟨10.5740/jaoacint.19-0063⟩
Article dans une revue hal-02628572 v1
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Use of partially hydrolysed formula in infancy and incidence of eczema, respiratory symptoms or food allergies in toddlers from the ELFE cohort

Camille Davisse-Paturet , Chantal Raherison , Karine Adel-Patient , Amandine Divaret-Chauveau , Corinne Bois et al.
Pediatric Allergy and Immunology, 2019, ⟨10.1111/pai.13094⟩
Article dans une revue inserm-02305833 v1
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Variable IgE cross-reactivity between peanut 2S-albumins: The case for measuring IgE to both Ara h 2 and Ara h 6.

Stéphane Hazebrouck , Blanche Guillon , Evelyne Paty , Stephen C Dreskin , Karine Adel-Patient et al.
Clinical and Experimental Allergy, 2019, 49, ⟨10.1111/cea.13432⟩
Article dans une revue hal-02193907 v1

Eaaci position paper: Influence of dietary fatty acids on asthma, food allergy, and atopic dermatitis

Carina Venter , Rosan W. Meyer , Bright I. Nwaru , Caroline Roduit , Eva Untersmayr et al.
Allergy, 2019, 74 (8), pp.1429-1444. ⟨10.1111/all.13764⟩
Article dans une revue (article de synthèse) hal-02629196 v1
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Breastfeeding Status and Duration and Infections, Hospitalizations for Infections and Antibiotic Use in the First Two Years of Life in the ELFE Cohort

Camille Davisse-Paturet , Karine Adel-Patient , Amandine Divaret-Chauveau , Juliette Pierson , Sandrine Lioret et al.
Nutrients, 2019, 11 (7), pp.1607. ⟨10.3390/nu11071607⟩
Article dans une revue inserm-02305847 v1
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The relevance of a digestibility evaluation in the allergenicity risk assessment of novel proteins. Opinion of a joint initiative of COST action ImpARAS and COST action INFOGEST

Kitty Verhoeckx , Katrine Lindholm Bøgh , Didier Dupont , Lotti Egger , Gabriele Gadermaier et al.
Food and Chemical Toxicology, 2019, 129, pp.405-423. ⟨10.1016/j.fct.2019.04.052⟩
Article dans une revue hal-02154659 v1

Evaluation of the efficiency of hydrolyzed whey formula to prevent cow’s milk allergy in the BALB/c mouse model

Amina Chikhi , Kamel‐eddine Elmecherfi , Hervé Bernard , Naima Cortes Perez , Omar Kheroua et al.
Pediatric Allergy and Immunology, 2019, 30 (3), pp.370-377. ⟨10.1111/pai.13017⟩
Article dans une revue hal-02617719 v1

Immune components of early breastmilk: Association with maternal factors and with reported food allergy in childhood

Mikaïl Berdi , Blandine de Lauzon-Guillain , Anne Forhan , Florence Anne Castelli , François Fenaille et al.
Pediatric Allergy and Immunology, 2019, 30 (1), pp.107-116. ⟨10.1111/pai.12998⟩
Article dans une revue hal-02619781 v1

Evidence for a MAIT-17–high phenotype in children with severe asthma

Guillaume Lezmi , Rola Abou-Taam , Nicolas Garcelon , Céline Dietrich , François Machavoine et al.
Journal of Allergy and Clinical Immunology, 2019, ⟨10.1016/j.jaci.2019.08.003⟩
Article dans une revue hal-02324249 v1
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Les dosages d’IgG anti-aliments : méthodes et pertinence clinique des résultats. Position du groupe de travail de biologie de la Société française d’allergologie

H. Chabane , V Doyen , F. Bienvenu , Karine Adel-Patient , J. Vitte et al.
Revue Française d'Allergologie, 2018, 58 (4), pp.334-357. ⟨10.1016/j.reval.2018.01.007⟩
Article dans une revue hal-01858895 v1
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Humoral and cellular immune response in Wistar Han RCC rats fed two genetically modified maize MON810 varieties for 90 days (EU 7th Framework Programme project GRACE)

Jana Tulinska , Karine Adel-Patient , Hervé Bernard , Aurelia Liskova , Miroslava Kuricova et al.
Archives of Toxicology, 2018, 92, pp.2385-2399. ⟨10.1007/s00204-018-2230-z⟩
Article dans une revue hal-02621931 v1
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Deep analysis of immune response and metabolic signature in children with food protein induced enterocolitis to cow's milk

Karine Adel-Patient , Guillaume Lezmi , Florence Castelli , Sibylle Blanc , Hervé Bernard et al.
Clinical and Translational Allergy, 2018, 8, ⟨10.1186/s13601-018-0224-9⟩
Article dans une revue hal-02622128 v1

Integrating allergen analysis within a risk assessment framework: approaches to development of targeted mass spectrometry methods for allergen detection and quantification in the iFAAM project

Chiara Nitride , Victoria Lee , Ivona Baricevic-Jones , Karine Adel-Patient , Sabine Baumgartner et al.
Journal of AOAC INTERNATIONAL, 2018, 101 (1), pp.83-90. ⟨10.5740/jaoacint.17-0393⟩
Article dans une revue (article de synthèse) hal-02621143 v1
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Intragastric administration of Lactobacillus casei BL23 induces regulatory FoxP3+RORγt+ T cells subset in mice

Naima Bermudez , Daniel Lozano Ojalvo , Matieny Dite Aicha Maiga , Stéphane Hazebrouck , Karine Adel-Patient
Beneficial Microbes, 2017, ⟨10.3920/BM2016.0174⟩
Article dans une revue hal-01605163 v1
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Neonatal mono-colonization of germ-free mice with Lactobacillus casei enhances casein immunogenicity after oral sensitization to cow's milk

Matieny Dite Aicha Maiga , Stéphanie S. Morin , Hervé Bernard , Sylvie Rabot , Karine Adel-Patient et al.
Molecular Nutrition and Food Research, 2017, 61 (9), pp.1-10. ⟨10.1002/mnfr.201600862⟩
Article dans une revue hal-02624576 v1

Modifying the infant's diet to prevent food allergy

Kate Grimshaw , Kirsty Logan , Sinead O'Donovan , Mairead Kiely , Karine Adel-Patient et al.
Archives of Disease in Childhood, 2017, 102 (2), pp.179-186. ⟨10.1136/archdischild-2015-309770⟩
Article dans une revue (article de synthèse) hal-02619972 v1
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Current challenges facing the assessment of the allergenic capacity of food allergens in animal models

Katrine Lindholm Bøgh , Jolanda van Bilsen , Robert Głogowski , Iván López-Expósito , Grégory Bouchaud et al.
Clinical and Translational Allergy, 2016, 6 (1), ⟨10.1186/s13601-016-0110-2⟩
Article dans une revue (article de synthèse) hal-02639998 v1

Non-IgE mediated food allergy

Daniel Lozano Ojalvo , Guillaume Lezmi , Naima Bermudez , Karine Adel-Patient
Drug Discovery Today: Disease Models, 2016, 17-18, pp.45-53. ⟨10.1016/j.ddmod.2016.09.003⟩
Article dans une revue hal-01602218 v1
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One-year oral toxicity study on a genetically modified maize MON810 variety in Wistar Han RCC rats (EU 7th Framework Programme project GRACE)

Dagmar Zeljenková , Radka Alacova , Júlia Ondrejková , Katarína Ambrušová , Mária Bartušová et al.
Archives of Toxicology, 2016, 90 (10), ⟨10.1007/s00204-016-1798-4⟩
Article dans une revue hal-02639999 v1

Assessment of IgE and IgG4 binding capacities of cow's milk proteins selectively altered by proteases

Alexandre Charcosset , Karine Adel-Patient , Christophe Dupont , Hervé Bernard
Journal of Agricultural and Food Chemistry, 2016, 64 (17), pp.3394 - 3404. ⟨10.1021/acs.jafc.5b01782⟩
Article dans une revue hal-02634004 v1
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Allergies alimentaires: mécanismes, biomarqueurs et impact de différents facteurs environnementaux

Karine Adel-Patient
Innovations Agronomiques, 2016, 52, pp.1-14. ⟨10.15454/1.5133529105822612E12⟩
Article dans une revue (article de synthèse) hal-02630095 v1
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Heat processing of peanut seed enhances the sensitization potential of the major peanut allergen Ara h 6

Blanche Guillon , Hervé Bernard , Marie-Francoise Drumare , Stéphane Hazebrouck , Karine Adel-Patient
Molecular Nutrition and Food Research, 2016, 60 (12), pp.2722-2735. ⟨10.1002/mnfr.201500923⟩
Article dans une revue hal-02637546 v1

Épigénétique et allergie alimentaire

Karine Adel-Patient
Revue Française d'Allergologie, 2015, 55 (3), pp.121-122. ⟨10.1016/j.reval.2015.01.026⟩
Article dans une revue hal-02630868 v1
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Allergenicity of peanut component Ara h 2: Contribution of conformational versus linear hydroxyproline-containing epitopes

Hervé Bernard , Blanche Guillon , Marie-Francoise Drumare , Evelyne Paty , Stephen C. Dreskin et al.
Journal of Allergy and Clinical Immunology, 2015, 135 (5), pp.1267-1274. ⟨10.1016/j.jaci.2014.10.025⟩
Article dans une revue hal-02641509 v1
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Further studies on the biological activity of hazelnut allergens

Fany Blanc , Hervé Bernard , Sandrine Ah-Leung , Laetitia L. Przybylski-Nicaise , P. Stahl Skov et al.
Clinical and Translational Allergy, 2015, 5 (1), ⟨10.1186/s13601-015-0066-7⟩
Article dans une revue hal-02634236 v1
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Influence of the route of exposure and the matrix on the sensitisation potency of a major cows’ milk allergen

Sophie Wavrin , Hervé Bernard , Jean-Michel J.-M. Wal , Karine Adel-Patient
Clinical and Translational Allergy, 2015, 5 (1), ⟨10.1186/s13601-015-0047-x⟩
Article dans une revue hal-02631090 v1

Respiratory allergen from house dust mite is present in human milk and primes for allergic sensitization in a mouse model of asthma

Patricia Macchiaverni , Ahmed Rekima , Mathilde Turfkruyer , Laurent Mascarell , Sabi Airouche et al.
Allergy, 2014, 69 (3), pp.395 - 398. ⟨10.1111/all.12332⟩
Article dans une revue hal-02637721 v1
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Assessment of the sensitizing potential of processed peanut proteins in Brown Norway rats: roasting does not enhance allergenicity

Stine Kroghsbo , Neil M. Rigby , Philip E. Johnson , Karine Adel-Patient , Katrine L. Bogh et al.
PLoS ONE, 2014, 9 (5), ⟨10.1371/journal.pone.0096475⟩
Article dans une revue hal-02635349 v1

Cutaneous or respiratory exposures to peanut allergens in mice and their impacts on subsequent oral exposure

Sophie Wavrin , Hervé Bernard , Jean-Michel J.-M. Wal , Karine Adel-Patient
International Archives of Allergy and Immunology, 2014, 164 (3), pp.189-199. ⟨10.1159/000363444⟩
Article dans une revue hal-02636778 v1

Peanut allergens are rapidly transferred in human breast milk and can prevent sensitization in mice

Hervé Bernard , Sandrine Ah Leung , Marie-Francoise Drumare , C. Feraudet-Tarisse , V. Verhasselt et al.
Allergy, 2014, 69 (7), pp.888-897. ⟨10.1111/all.12411⟩
Article dans une revue hal-02631176 v1
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Goat's milk allergy without cow's milk allergy: suppression of non-cross-reactive epitopes on caprine beta-casein

Stéphane Hazebrouck , Sandrine Ah-Leung-Poullias , E. Bidat , E. Paty , Marie-Francoise Drumare et al.
Clinical and Experimental Allergy, 2014, 44 (4), pp.602-610. ⟨10.1111/cea.12261⟩
Article dans une revue istex hal-02639662 v1
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Ninety-day oral toxicity studies on two genetically modified maize MON810 varieties in Wistar Han RCC rats (EU 7th Framework Programme project GRACE)

Dagmar Zeljenková , Katarína Ambrušová , Mária Bartušová , Anton Kebis , Jevgenij Kovrižnych et al.
Archives of Toxicology, 2014, 88 (12), pp.2289-2314. ⟨10.1007/s00204-014-1374-8⟩
Article dans une revue hal-02633370 v1

Production of human antibodies by in vitro immunization using a fusion protein containing the transcriptional transactivator of HIV-1

Mazhoura Ait Mebarek , A. Wijkhuisen , Karine Adel-Patient , P. Lamourette , M. Léonetti et al.
Journal of Immunological Methods, 2013, 396 (1-2), pp.96-106. ⟨10.1016/j.jim.2013.07.015⟩
Article dans une revue istex hal-02649348 v1

Immunomodulatory Potential of Partially Hydrolyzed beta-Lactoglobulin and Large Synthetic Peptides

Karine Adel-Patient , Sophie Nutten , Hervé Bernard , Rodolphe Fritsche , Sandrine Ah-Leung-Poullias et al.
Journal of Agricultural and Food Chemistry, 2012, 60 (43), pp.10858 - 10866. ⟨10.1021/jf3031293⟩
Article dans une revue hal-02651963 v1

Effect of roasting on the allergenicity of major peanut allergens Ara h 1 and Ara h 2/6: the necessity of degranulation assays

Y. M. Vissers , M. Iwan , Karine Adel-Patient , P. Stahl Skov , N. M. Rigby et al.
Clinical and Experimental Allergy, 2011, 41 (11), pp.1631 - 1642. ⟨10.1111/j.1365-2222.2011.03830.x⟩
Article dans une revue istex hal-02646335 v1
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Immunological and metabolomic impacts of administration of Cry1Ab protein and MON 810 maize in mouse

Karine Adel-Patient , Odette Guimaraes , Alain Paris , Marie-Francoise Drumare , Sandrine Ah-Leung-Poullias et al.
PLoS ONE, 2011, 6 (1), pp.e16346. ⟨10.1371/journal.pone.0016346⟩
Article dans une revue hal-01019726 v1

Oral tolerance and Treg cells are induced in BALB/c mice after gavagewith bovine beta-lactoglobulin

Karine Adel-Patient , Sophie Wavrin , Hervé Bernard , Narimane Meziti , Sandrine Ah-Leung-Poullias et al.
Allergy, 2011, 66 (10), pp.1312 - 1321. ⟨10.1111/j.1398-9995.2011.02653.x⟩
Article dans une revue hal-02646694 v1

Regulatory T Cells Control Type I Food Allergy to Beta-Lactoglobulin in Mice

Reem Kanjarawi , Christophe Dercamp , Nathalie Etchart , Karine Adel-Patient , Jean-François Nicolas et al.
International Archives of Allergy and Immunology, 2011, 156 (4), pp.387 - 396. ⟨10.1159/000323940⟩
Article dans une revue hal-02645403 v1
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Boiling peanut Ara h 1 results in the formation of aggregates with reduced allergenicity

Fany Blanc , Yvonne M. Vissers , Karine Adel-Patient , Neil M. Rigby , Alan R. Mackie et al.
Molecular Nutrition and Food Research, 2011, 55 (12), pp.1887 - 1894. ⟨10.1002/mnfr.201100251⟩
Article dans une revue istex hal-02647106 v1
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Effect of Heating and Glycation on the Allergenicity of 2S Albumins (Ara h 2/6) from Peanut

Yvonne M. Vissers , Fany Blanc , Per Stahl Skov , Phil E. Johnson , Neil M. Rigby et al.
PLoS ONE, 2011, 6 (8), ⟨10.1371/journal.pone.0023998⟩
Article dans une revue hal-02649179 v1

Immunoglobulin-E-binding epitopes of wheat allergens in patients withfood allergy to wheat and in mice experimentally sensitized to wheat proteins

Sandra Denery-Papini , Marie Bodinier , Florence Pineau , Sylvie Triballeau , Olivier O. Tranquet et al.
Clinical and Experimental Allergy, 2011, 41 (10), pp.1478 - 1492. ⟨10.1111/j.1365-2222.2011.03808.x⟩
Article dans une revue istex hal-02649440 v1

In vitro digestion of Cry1Ab proteins and analysis of the impact on their immunoreactivity

Valeria Guimaraes , Marie-Francoise Drumare , Didier Lereclus , Michel Gohar , Patricia Lamourette et al.
Journal of Agricultural and Food Chemistry, 2010, 58 (5), pp.3222-3231. ⟨10.1021/jf903189j⟩
Article dans une revue hal-02660053 v1

Block Copolymers Have Differing Adjuvant Effects on the Primary Immune Response Elicited by Genetic Immunization and on Further Induced Allergy

Karine Adel-Patient , Laetitia Pothelune , Sandrine Ah-Leung , Jean-Michel Wal , Christophe Créminon et al.
Clinical and Vaccine Immunology, 2010, 17 (1), pp. 36-42. ⟨10.1128/CVI.00275-09⟩
Article dans une revue hal-04084105 v1

Allergy therapy by intranasal administration with recombinant Lactococcus lactis Producing bovine beta-lactoglobulin

Naima Bermudez , Sandrine Ah-Leung-Poullias , Luis Bermudez Humaran , Gerard Corthier , Philippe Langella et al.
International Archives of Allergy and Immunology, 2009, 150 (1), pp.25-31. ⟨10.1159/000210377⟩
Article dans une revue hal-01204327 v1

Capacity of purified peanut allergens to induce degranulation in a functional in vitro assay: Ara h 2 and Ara h 6 are the most efficient elicitors

Fany Blanc , Karine Adel-Patient , M.-F. Drumare , E. Paty , J.-M. Wal et al.
Clinical & Experimental Allergy, 2009, 39 (8), pp.1277-1285. ⟨10.1111/j.1365-2222.2009.03294.x⟩
Article dans une revue istex hal-03182707 v1

Sensitization and Elicitation of an Allergic Reaction to Wheat Gliadins in Mice

Marie Bodinier , Michael Leroy , Sandrine Ah-Leung , Fany Blanc , Olivier O. Tranquet et al.
Journal of Agricultural and Food Chemistry, 2009, 57 (4), pp.1219-1225. ⟨10.1021/jf802898u⟩
Article dans une revue hal-02663160 v1
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Influence of the route of administration on immunomodulatory properties of bovine beta-lactoglobulin-producing Lactobacillus casei

Stéphane Hazebrouck , Laetitia L. Przybylski-Nicaise , Sandrine Ah-Leung-Poullias , Karine Adel-Patient , Gerard G. Corthier et al.
Vaccine, 2009, 27 (42), pp.5800-5805. ⟨10.1016/j.vaccine.2009.07.064⟩
Article dans une revue istex hal-02661975 v1

Allergic sensitization to bovine beta-lactoglobulin: comparison between germ-free and conventional BALB/c mice

Stéphane Hazebrouck , Laetitia L. Przybylski-Nicaise , Sandrine Ah-Leung-Poullias , Karine Adel-Patient , Gerard G. Corthier et al.
International Archives of Allergy and Immunology, 2009, 148 (1), pp.65-72. ⟨10.1159/000151507⟩
Article dans une revue hal-02659705 v1

Animal models of food allergy. Application to wheat proteins

Marie Bodinier , Michael Leroy , Karine Adel-Patient
Revue Française d'Allergologie et d'Immunologie Clinique, 2008, 48 (8), pp.526-532. ⟨10.1016/j.allerg.2008.09.001⟩
Article dans une revue istex hal-02656942 v1

Current prophylactic and therapeutic uses of a recombinant lactococcus lactis strain secreting biologically active interleukin-12

Luis L. Bermudez Humaran , Naima G. Cortes-Perez , Sandrine Ah-Leung , Francois F. Lefèvre , Guang Yang et al.
Journal of Molecular Microbiology and Biotechnology, 2008, 14 (1-3), pp.80-89. ⟨10.1159/000106086⟩
Article dans une revue hal-02668362 v1

Update on optimized purification and characterization of natural milk allergens

Fany Blanc , Hervé Bernard , Stefano Alessandri , Merima Bublin , Evelyne Paty et al.
Molecular Nutrition & Food Research, 2008, ⟨10.1002/mnfr.200700283⟩
Article dans une revue istex hal-03182708 v1
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Intranasal coadministration of live lactococci producing interleukin-12 and a major cow's milk allergen inhibits allergic reaction in mice

Naima Bermudez , Sandrine Ah-Leung-Poullias , Luis Bermudez Humaran , Gerard Corthier , Jean-Michel Wal et al.
Clinical and Vaccine Immunology, 2007, 14 (3), pp.226-233. ⟨10.1128/CVI.00299-06⟩
Article dans une revue hal-01204326 v1

Influence of the route of immunization and the nature of the bacterial vector on immunogenicity of mucosal vaccines based on lactic acid bacteria

Naima G. Cortes-Perez , Francois F. Lefèvre , Gerard G. Corthier , Karine Adel-Patient , Philippe P. Langella et al.
Vaccine, 2007, 25 (36), pp.6581-6588. ⟨10.1016/j.vaccine.2007.06.062⟩
Article dans une revue istex hal-02658022 v1
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Constitutive delivery of bovine beta-lactoglobulin to the digestive tracts of gnotobiotic mice by engineered Lactobacillus casei

Stéphane Hazebrouck , Raish Oozeer , Karine Adel-Patient , Philippe P. Langella , Sylvie S. Rabot et al.
Applied and Environmental Microbiology, 2006, 72 (12), pp.7460-7467. ⟨10.1128/AEM.01032-06⟩
Article dans une revue hal-02659925 v1
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Improvement of bovine beta-lactoglobulin production and secretion by Lactococcus lactis

Sébastien Nouaille , Luis L. Bermudez Humaran , Karine Adel-Patient , J. Commissaire , Alexandra A. Gruss et al.
Brazilian Journal of Medical and Biological Research, 2005, 38 (3), pp.353-359. ⟨10.1590/S0100-879X2005000300005⟩
Article dans une revue hal-02680726 v1

Oral administration of recombinant Lactococcus lactis expressing bovine beta-lactoglobulin partially prevents mice from sensitization

Karine Adel-Patient , Sandrine Ah-Leung , Christophe Créminon , Sébastien Nouaille , Jean-Marc Chatel et al.
Clinical and Experimental Allergy, 2005, 35 (4), pp.539-546. ⟨10.1111/j.1365-2222.2005.02225.x⟩
Article dans une revue istex hal-02680347 v1

Characterization of a <em>Lactococcus lactis</em> strain that secretes a major epitope of bovine β-lactoglobulin and evaluation of its immunogenicity in mice.

Jean-Marc Chatel , Sébastien Nouaille , Karine Adel-Patient , Yves Le Loir , Herman Boe et al.
Applied and Environmental Microbiology, 2003, 69 (11), pp.6620-6627. ⟨10.1128/AEM.69.11.6620-6627.2003⟩
Article dans une revue hal-02677536 v1

Epitopic characterization of native bovine β-lactoglobulin

Gilles Clement , Didier Boquet , Yveline Frobert , Hervé Bernard , Luc Negroni et al.
Journal of Immunological Methods, 2002, 266 (1-2), pp. 67-78. ⟨10.1016/S0022-1759(02)00149-7⟩
Article dans une revue istex hal-04083984 v1

Genetic Immunisation with Bovine β-Lactoglobulin cDNA Induces a Preventive and Persistent Inhibition of Specific Anti-BLG IgE Response in Mice

Karine Adel-Patient , Christophe Creminon , Didier Boquet , Jean-Michel Wal , Jean-Marc Chatel
International Archives of Allergy and Immunology, 2001, 126 (1), pp. 59-67. ⟨10.1159/000049495⟩
Article dans une revue hal-04083981 v1

Characterization of allergens in milk

J.M. Wal , Hervé Bernard , Gilles G. Clément , Jean-Marc Chatel , Karine Adel-Patient
Current Allergy and Clinical Immunology, 2001, 14 (3), pp.4-10
Article dans une revue hal-02670593 v1

Induction of Mucosal Immune Response after Intranasal or Oral Inoculation of Mice with Lactococcus lactis Producing Bovine Beta-Lactoglobulin

Jean-Marc Chatel , Philippe Langella , Karine Adel-Patient , Jacqueline Commissaire , Jean-Michel Wal et al.
Clinical and Diagnostic Laboratory Immunology, 2001, 8 (3), pp. 545-551. ⟨10.1128/CDLI.8.3.545-551.2001⟩
Article dans une revue hal-04083978 v1

Genetic immunisation with bovine beta-lactoglobulin cDNA induces a preventive and persistent inhibition of specific anti-BLG IgE response in mice

Karine Adel-Patient , Christophe Créminon , D. Boquet , J.M. Wal , Jean-Marc Chatel
International Archives of Allergy and Immunology, 2001, 126, pp.59-67
Article dans une revue hal-02673675 v1

Induction of mucosal immune response after intranasal or oral inoculation of mice with Lactococcus lactis producing bovine beta-lactoglobulin

Jean-Marc Chatel , Philippe P. Langella , Karine Adel-Patient , J. Commissaire , J.M. Wal et al.
Clinical and Diagnostic Laboratory Immunology, 2001, 8 (3), pp.545-551
Article dans une revue hal-02673341 v1

Prévention d'une réponse IgE spécifique de la β-lactoglobuline bovine chez la souris par immunisation génique

Karine Adel-Patient , C Creminon , J Wal , Jean-Marc Chatel
Revue Française d'Allergologie et d'Immunologie Clinique, 2000, 40 (2), pp. 77-81. ⟨10.1016/S0335-7457(00)80005-2⟩
Article dans une revue istex hal-04083973 v1

Molecular basis of IgE cross-reactivity between human beta-casein and bovine beta-casein, a major allergen of milk

Hervé Bernard , Luc Négroni , Jean-Marc Chatel , Gilles G. Clément , Karine Adel-Patient et al.
Molecular Immunology, 2000, 37, pp.161-167
Article dans une revue hal-02688298 v1

Evaluation of a high IgE-responder mouse model of allergy to bovine beta-lactoglobulin (BLG) : development of sandwich immunoassays for total and allergen-specific IgE, IgG1 and IgG2a in BLG-sensitized mice

Karine Adel-Patient , Christophe Créminon , Hervé Bernard , Gilles G. Clément , Luc Négroni et al.
Journal of Immunological Methods, 2000, 235, pp.21-32
Article dans une revue hal-02694160 v1

Prévention d'une réponse IgE spécifique de la beta-lactoglobuline bovine chez la souris par immunisation génique

Karine Adel-Patient , Christophe Créminon , J.M. Wal , Jean-Marc Chatel
Revue Française d'Allergologie et d'Immunologie Clinique, 2000, 40, pp.171-184
Article dans une revue hal-02690357 v1

Molecular basis of IgE cross-reactivity between human β-casein and bovine β-casein, a major allergen of milk

Hervé Bernard , Luc Négroni , Jean-Marc Chatel , Karine Adel-Patient , G. Peltre et al.
Molecular Immunology, 2000, 37 (3-4), pp. 161-167. ⟨10.1016/S0022-1759(99)00210-0⟩
Article dans une revue istex hal-04083972 v1

Expression of a lipocalin in prokaryote and eukaryote cells : quantification and structural characterization of recombinant bovine beta-lactoglobulin

Jean-Marc Chatel , Karine Adel-Patient , Christophe Créminon , J.M. Wal
Protein Expression and Purification, 1999, 16, pp.70-75
Article dans une revue hal-02697400 v1

Expression of a Lipocalin in Prokaryote and Eukaryote Cells: Quantification and Structural Characterization of Recombinant Bovine β-Lactoglobulin

Jean-Marc Chatel , Karine Adel-Patient , Christophe Créminon , Jean-Michel Wal
Protein Expression and Purification, 1999, 16 (1), pp.70-75. ⟨10.1006/prep.1999.1055⟩
Article dans une revue istex hal-04083970 v1

Mécanisme d’induction de la tolérance orale aux antigènes alimentaires

Karine Adel-Patient
Allergies alimentaires : nouveaux concepts, affections actuelles, perspectives thérapeutiques, Elsevier Masson S.A.S, 2017
Chapitre d'ouvrage hal-02786706 v1