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Karine Adel-Patient

Directrice de Recherche INRAE Université Paris-Saclay, CEA, INRAE Unité Médicaments et Technologies pour la Santé DRF/Institut Joliot/MTS/SPI/Laboratoire d'ImmunoAllergie Alimentaire
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Publications

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Prenatal dietary exposure to mixtures of chemicals is associated with allergy or respiratory diseases in children in the ELFE nationwide cohort

Manel Ghozal , Manik Kadawathagedara , Rosalie Delvert , Amandine Divaret-Chauveau , Chantal Raherison
Environmental Health, 2024, 23 (1), pp.5. ⟨10.1186/s12940-023-01046-y⟩
Journal articles anses-04426377v1
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Long-term exposure from perinatal life to food-grade TiO$_2$ alters intestinal homeostasis and predisposes to food allergy in young mice

Mohammad Issa , Chloé Michaudel , Marine Guinot , Marta Grauso‐culetto , Blanche Guillon
Allergy, 2024, 79 (2), pp.471-484. ⟨10.1111/all.15960⟩
Journal articles hal-04334514v1
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Optimization of a sample preparation workflow based on UHPLC-MS/MS method for multi-allergen detection in chocolate: An outcome of the ThRAll project

Jean Henrottin , Rosa Pilolli , Anne-Catherine Huet , Christof van Poucke , Chiara Nitride
Food Control, 2023, 143, pp.109256. ⟨10.1016/j.foodcont.2022.109256⟩
Journal articles hal-03761018v1
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Maternal Diet Quality during Pregnancy and Allergic and Respiratory Multimorbidity Clusters in Children from the EDEN Mother–Child Cohort

Rosalie Delvert , Manel Ghozal , Karine Adel-Patient , Manik Kadawathagedara , Barbara Heude
Nutrients, 2023, 15 (1), pp.146. ⟨10.3390/nu15010146⟩
Journal articles hal-03949617v1
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Pre-, pro-, syn-, and Postbiotics in Infant Formulas: What Are the Immune Benefits for Infants?

Anaïs Lemoine , Patrick Tounian , Karine Adel-Patient , Muriel Thomas
Nutrients, 2023, 15, ⟨10.3390/nu15051231⟩
Journal articles hal-04012865v1
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Assessment of local and systemic signature of eosinophilic esophagitis (EoE) in children through multi-omics approaches

Karine Adel-Patient , Florence Campeotto , Marta Grauso , Blanche Guillon , Marco Moroldo
Frontiers in Immunology, 2023, 14, pp.1108895. ⟨10.3389/fimmu.2023.1108895⟩
Journal articles hal-04032831v1

Long‐term exposure from perinatal life to food‐grade TiO 2 alters intestinal homeostasis and predisposes to food allergy in young mice

Mohammad Issa , Chloé Michaudel , Marine Guinot , Marta Grauso-Culetto , Blanche Guillon
Allergy, 2023, 79 (2), pp.471-484. ⟨10.1111/all.15960⟩
Journal articles hal-04466073v1
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Complementary feeding practices are related to the risk of food allergy in the ELFE cohort

T. Adam , A Divaret‐chauveau , C. Roduit , Karine Adel-Patient , A. Deschildre
Allergy, 2023, 79 (9), pp.2456-2466. ⟨10.1111/all.15828⟩
Journal articles hal-04174304v1
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Prenatal dietary exposure to chemicals and allergy or respiratory diseases in children in the EDEN mother–child cohort

Manel Ghozal , Manik Kadawathagedara , Rosalie Delvert , Karine Adel-Patient , Muriel Tafflet
Environment International, 2023, 180, pp.108195. ⟨10.1016/j.envint.2023.108195⟩
Journal articles hal-04229520v1
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Enrichment of Formula in Probiotics or Prebiotics and Risk of Infection and Allergic Diseases up to Age 5.5 Years in the Nationwide Etude Longitudinale Française depuis l'Enfance (ELFE) Cohort

Moufidath Adjibade , Camille Davisse-Paturet , Amandine Divaret-Chauveau , Karine Adel-Patient , Chantal Raherison
Journal of Nutrition, Health & Aging, 2022, 152 (4), pp.1138-1148. ⟨10.1093/jn/nxac013⟩
Journal articles hal-03694295v1
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Route of Sensitization to Peanut Influences Immune cell recruitment at various mucosal sites in mouse: An integrative analysis

Mélanie Briard , Marine Guinot , Marta Grauso , Blanche Guillon , Stéphane Hazebrouck
Nutrients, 2022, 14 (4), pp.790. ⟨10.3390/nu14040790⟩
Journal articles hal-03589190v1
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Prevalence of Food Allergy in France up to 5.5 Years of Age: Results from the ELFE Cohort

Sarah Tamazouzt , Karine Adel-Patient , Antoine Deschildre , Caroline Roduit , Marie Aline Charles
Nutrients, 2022, 14 (17), pp.3624. ⟨10.3390/nu14173624⟩
Journal articles hal-03786831v1
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Perinatal exposure to foodborne inorganic nanoparticles: A role in the susceptibility to food allergy?

Mohammad Issa , Gilles Rivière , Eric Houdeau , Karine Adel-Patient
Frontiers in Allergy, 2022, 3 (1067281), ⟨10.3389/falgy.2022.1067281⟩
Journal articles hal-03902955v1
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Rapid structural characterization of human milk oligosaccharides and distinction of their isomers using trapped ion mobility spectrometry time‐of‐flight mass spectrometry

Estelle Rathahao-Paris , Aurélie Delvaux , Meijie Li , Blanche Guillon , Eric Venot
Journal of Mass Spectrometry, 2022, 57 (10), 7 p. ⟨10.1002/JMS.4885⟩
Journal articles hal-03940699v1
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Immunodominant conformational and linear IgE epitopes lie in a single segment of Ara h 2

Stéphane Hazebrouck , Sarita Patil , Blanche Guillon , Nicole Lahood , Stephen Dreskin
Journal of Allergy and Clinical Immunology, 2022, 150 (1), pp.131-139. ⟨10.1016/j.jaci.2021.12.796⟩
Journal articles hal-03889685v1
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Role of dietary fiber in promoting immune health—An EAACI position paper

Carina Venter , Rosan Meyer , Matthew Greenhawt , Isabella Pali-Schöll , Bright Nwaru
Allergy, 2022, 77 (11), pp.3185-3198. ⟨10.1111/all.15430⟩
Journal articles hal-04009145v1
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The Human Meconium Metabolome and Its Evolution during the First Days of Life

Nihel Bekhti , Florence Castelli , Alain Paris , Blanche Guillon , Christophe Junot
Metabolites, 2022, 12 (5), pp.414. ⟨10.3390/metabo12050414⟩
Journal articles hal-04008723v1

Development of incurred chocolate bars and broth powder with six fully characterised food allergens as test materials for food allergen analysis

Anne-Catherine Huet , Melody Paulus , Jean Henrottin , Chantal Brossard , Olivier Tranquet
Analytical and Bioanalytical Chemistry, 2022, 414 (8), pp.2553-2570. ⟨10.1007/s00216-022-03912-z⟩
Journal articles hal-03630067v1
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Sensitization Potency of Sunflower Seed Protein in a Mouse Model: Identification of 2S‐Albumins More Allergenic Than SFA‐8

Jihana Achour , Marine Guinot , Blanche Guillon , Romain Kapel , Olivier Galet
Molecular Nutrition and Food Research, 2021, 65 (18), ⟨10.1002/mnfr.202100369⟩
Journal articles hal-03322664v1

Observational Study of Chlorpromazine in Hospitalized Patients with COVID-19

Karine Adel-Patient , Marta Grauso , Rola Abou-Taam , Blanche Guillon , Céline Dietrich
Clinical Drug Investigation, 2021, 41 (3), pp.221-233. ⟨10.1111/all.14759⟩
Journal articles hal-04360161v1
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Organic food consumption during the complementary feeding period and respiratory or allergic diseases up to age 5.5 years in the ELFE cohort

David Payet , Moufidath Adjibade , Julia Baudry , Manel Ghozal , Aurore Camier
Frontiers in Nutrition, 2021, 8, pp.791430. ⟨10.3389/fnut.2021.791430⟩
Journal articles hal-03525019v1
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Enrichment of infant formula with long-chain polyunsaturated fatty acids and risk of infection and allergy in the nationwide ELFE birth cohort

Moufidath Adjibade , Camille Davisse-Paturet , Jonathan Y Bernard , Karine Adel-Patient , Amandine Divaret-Chauveau
Allergy, 2021, 77 (5), pp.1522-1533. ⟨10.1111/all.15137⟩
Journal articles hal-03693984v1
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Immune signatures distinguish frequent from non-frequent exacerbators among children with severe asthma

Karine Adel-Patient , Marta Grauso , Rola Abou Taam , Blanche Guillon , Céline Dietrich
Allergy, 2021, 76 (7), pp.2261-2264. ⟨10.1111/all.14759⟩
Journal articles hal-03133856v1

Immune signatures distinguish frequent from non‐frequent exacerbators among children with severe asthma

Karine Adel-Patient , Marta Grauso , Rola Abou-Taam , Blanche Guillon , Céline Dietrich
Allergy, 2021, 76 (7), pp.2261-2264. ⟨10.1111/all.14759⟩
Journal articles hal-03887168v1
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A Comprehensive Analysis of Immune Constituents in Blood and Bronchoalveolar Lavage Allows Identification of an Immune Signature of Severe Asthma in Children

Karine Adel-Patient , Marta Grauso , Rola Abou-Taam , Blanche Guillon , Céline Dietrich
Frontiers in Immunology, 2021, 12, ⟨10.3389/fimmu.2021.700521⟩
Journal articles hal-03327837v1

Discovery based high resolution MS/MS analysis for selection of allergen markers in chocolate and broth powder matrices

Rosa Pilolli , Christof van Poucke , Elisabetta de Angelis , Chiara Nitride , Marc de Loose
Food Chemistry, 2021, 343, pp.128533. ⟨10.1016/j.foodchem.2020.128533⟩
Journal articles hal-03153322v1

A Comprehensive Analysis of Immune Constituents in Blood and Bronchoalveolar Lavage Allows Identification of an Immune Signature of Severe Asthma in Children

Karine Adel-Patient , Marta Grauso , Rola Abou-Taam , Blanche Guillon , Céline Dietrich
Frontiers in Immunology, 2021, 12 (12), pp.1071-1077. ⟨10.3389/fimmu.2021.700521⟩
Journal articles hal-03887070v1
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Allergen risk assessment for specific allergy to small ruminant's milk: development of sensitive immunoassays to detect goat's and sheep's milk contaminations in dairy food matrices

Hervé Bernard , Stéphane Hazebrouck , Nicolas Gaiani , Karine Adel-Patient
Frontiers in Allergy, 2021, 2 (733875), ⟨10.3389/falgy.2021.733875⟩
Journal articles hal-03889673v1
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Trapped ion mobility spectrometry time-of-flight mass spectrometry for high throughput and high resolution characterization of human milk oligosaccharide isomers

Aurélie Delvaux , Estelle Rathahao-Paris , Blanche Guillon , Sophie Cholet , Karine Adel-Patient
Analytica Chimica Acta, 2021, 1180, pp.338878. ⟨10.1016/j.aca.2021.338878⟩
Journal articles hal-03533998v1

The Effect of the Food Matrix on the In Vitro Bio‐Accessibility and IgE Reactivity of Peanut Allergens

Huan Rao , Ivona Baricevic , Hervé Bernard , Frances Smith , Rebekah Sayers
Molecular Nutrition and Food Research, 2020, 64 (14), pp.1-9. ⟨10.1002/mnfr.201901093⟩
Journal articles hal-03349630v1
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Prevention of Allergy to a Major Cow's Milk Allergen by Breastfeeding in Mice Depends on Maternal Immune Status and Oral Exposure During Lactation

Karine Adel-Patient , Hervé Bernard , François Fenaille , Stéphane Hazebrouck , Christophe Junot
Frontiers in Immunology, 2020, 11, ⟨10.3389/fimmu.2020.01545⟩
Journal articles hal-03321788v1
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Administration of Extensive Hydrolysates From Caseins and Lactobacillus rhamnosus GG Probiotic Does Not Prevent Cow’s Milk Proteins Allergy in a Mouse Model

Karine Adel-Patient , Marine Guinot , Blanche Guillon , Hervé Bernard , Amina Chikhi
Frontiers in Immunology, 2020, 11, ⟨10.3389/fimmu.2020.01700⟩
Journal articles hal-03346706v1
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Circulating Ara h 6 as a marker of peanut protein absorption in tolerant and allergic humans following ingestion of peanut‐containing foods

Hervé Bernard , Paul J Turner , Sandrine Ah‐leung , Monica Ruiz‐garcia , Elizabeth Naomi Clare Mills
Clinical and Experimental Allergy, 2020, 50 (9), pp.1093-1102. ⟨10.1111/cea.13706⟩
Journal articles hal-03349239v1

Immunological Outcomes of Allergen-Specific Immunotherapy in Food Allergy

Ann-Marie Malby Schoos , Dominique Bullens , Bo Lund Chawes , Joana Costa , Liselot de Vlieger
Frontiers in Immunology, 2020, 11, ⟨10.3389/fimmu.2020.568598⟩
Journal articles hal-03349171v1
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Breastfeeding initiation or duration and longitudinal patterns of infections up to 2 years and skin rash and respiratory symptoms up to 8 years in the EDEN mother–child cohort

Camille Davisse-Paturet , Karine Adel-Patient , Anne Forhan , Sandrine Lioret , Isabella Annesi‐maesano
Maternal and Child Nutrition, 2020, 16 (3), ⟨10.1111/mcn.12935⟩
Journal articles hal-02904859v1
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Critical review on proteotypic peptide marker tracing for six allergenic ingredients in incurred foods by mass spectrometry

Rosa Pilolli , Chiara Nitride , Nathalie Gillard , Anne-Catherine Huet , Christof van Poucke
Food Research International, 2020, 128, pp.108747. ⟨10.1016/j.foodres.2019.108747⟩
Journal articles hal-02410519v1
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Basal Ti Level in the human placenta and meconium and evidence of a materno-foetal transfer of food-grade TiO2 nanoparticles in an ex vivo placental perfusion model

Adèle Guillard , Eric Gaultier , Christel Cartier , Laurent Devoille , Johanna Noireaux
Particle and Fibre Toxicology, 2020, 17 (1), ⟨10.1186/s12989-020-00381-z⟩
Journal articles hal-02945928v2
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Detection and quantification of allergens in foods and minimum eliciting doses in food-allergic individuals (Thrall)

E.N. Clare Mills , Karine Adel-Patient , Hervé Bernard , Marc de Loose , Nathalie Gillard
Journal of AOAC INTERNATIONAL, 2019, 102 (5), pp.1346-1353. ⟨10.5740/jaoacint.19-0063⟩
Journal articles hal-02628572v1

Eaaci position paper: Influence of dietary fatty acids on asthma, food allergy, and atopic dermatitis

Carina Venter , Rosan W. Meyer , Bright I. Nwaru , Caroline Roduit , Eva Untersmayr
Allergy, 2019, 74 (8), pp.1429-1444. ⟨10.1111/all.13764⟩
Journal articles hal-02629196v1
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Variable IgE cross-reactivity between peanut 2S-albumins: The case for measuring IgE to both Ara h 2 and Ara h 6.

Stéphane Hazebrouck , Blanche Guillon , Evelyne Paty , Stephen C Dreskin , Karine Adel-Patient
Clinical and Experimental Allergy, 2019, 49, ⟨10.1111/cea.13432⟩
Journal articles hal-02193907v1

Evidence for a MAIT-17–high phenotype in children with severe asthma

Guillaume Lezmi , Rola Abou-Taam , Nicolas Garcelon , Céline Dietrich , François Machavoine
Journal of Allergy and Clinical Immunology, 2019, ⟨10.1016/j.jaci.2019.08.003⟩
Journal articles hal-02324249v1
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Reply to J. Heinrich

Camille Davisse‐paturet , Chantal Raherison , Karine Adel-Patient , Amandine Divaret-Chauveau , Marie‐noëlle Dufourg
Pediatric Allergy and Immunology, 2019, 31, pp.108-109. ⟨10.1111/pai.13146⟩
Journal articles hal-02898234v1
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Breastfeeding Status and Duration and Infections, Hospitalizations for Infections and Antibiotic Use in the First Two Years of Life in the ELFE Cohort

Camille Davisse-Paturet , Karine Adel-Patient , Amandine Divaret-Chauveau , Juliette Pierson , Sandrine Lioret
Nutrients, 2019, 11 (7), pp.1607. ⟨10.3390/nu11071607⟩
Journal articles inserm-02305847v1

Evaluation of the efficiency of hydrolyzed whey formula to prevent cow’s milk allergy in the BALB/c mouse model

Amina Chikhi , Kamel‐eddine Elmecherfi , Hervé Bernard , Naima Cortes Perez , Omar Kheroua
Pediatric Allergy and Immunology, 2019, 30 (3), pp.370-377. ⟨10.1111/pai.13017⟩
Journal articles hal-02617719v1

Immune components of early breastmilk: Association with maternal factors and with reported food allergy in childhood

Mikaïl Berdi , Blandine de Lauzon-Guillain , Anne Forhan , Florence Anne Castelli , François Fenaille
Pediatric Allergy and Immunology, 2019, 30 (1), pp.107-116. ⟨10.1111/pai.12998⟩
Journal articles hal-02619781v1
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The relevance of a digestibility evaluation in the allergenicity risk assessment of novel proteins. Opinion of a joint initiative of COST action ImpARAS and COST action INFOGEST

Kitty Verhoeckx , Katrine Lindholm Bøgh , Didier Dupont , Lotti Egger , Gabriele Gadermaier
Food and Chemical Toxicology, 2019, 129, pp.405-423. ⟨10.1016/j.fct.2019.04.052⟩
Journal articles hal-02154659v1
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Use of partially hydrolysed formula in infancy and incidence of eczema, respiratory symptoms or food allergies in toddlers from the ELFE cohort

Camille Davisse-Paturet , Chantal Raherison , Karine Adel-Patient , Amandine Divaret-Chauveau , Corinne Bois
Pediatric Allergy and Immunology, 2019, ⟨10.1111/pai.13094⟩
Journal articles inserm-02305833v1
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Humoral and cellular immune response in Wistar Han RCC rats fed two genetically modified maize MON810 varieties for 90 days (EU 7th Framework Programme project GRACE)

Jana Tulinska , Karine Adel-Patient , Hervé Bernard , Aurelia Liskova , Miroslava Kuricova
Archives of Toxicology, 2018, 92, pp.2385-2399. ⟨10.1007/s00204-018-2230-z⟩
Journal articles hal-02621931v1

Integrating allergen analysis within a risk assessment framework: approaches to development of targeted mass spectrometry methods for allergen detection and quantification in the iFAAM project

Chiara Nitride , Victoria Lee , Ivona Baricevic-Jones , Karine Adel-Patient , Sabine Baumgartner
Journal of AOAC INTERNATIONAL, 2018, 101 (1), pp.83-90. ⟨10.5740/jaoacint.17-0393⟩
Journal articles hal-02621143v1
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Deep analysis of immune response and metabolic signature in children with food protein induced enterocolitis to cow's milk

Karine Adel-Patient , Guillaume Lezmi , Florence Castelli , Sibylle Blanc , Hervé Bernard
Clinical and Translational Allergy, 2018, 8, ⟨10.1186/s13601-018-0224-9⟩
Journal articles hal-02622128v1
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Les dosages d’IgG anti-aliments : méthodes et pertinence clinique des résultats. Position du groupe de travail de biologie de la Société française d’allergologie

H. Chabane , V Doyen , F. Bienvenu , Karine Adel-Patient , J. Vitte
Revue francaise d'allergologie, 2018, 58 (4), pp.334-357. ⟨10.1016/j.reval.2018.01.007⟩
Journal articles hal-01858895v1
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Neonatal mono-colonization of germ-free mice with Lactobacillus casei enhances casein immunogenicity after oral sensitization to cow's milk

Matieny Dite Aicha Maiga , Stéphanie S. Morin , Hervé Bernard , Sylvie Rabot , Karine Adel-Patient
Molecular Nutrition and Food Research, 2017, 61 (9), pp.1-10. ⟨10.1002/mnfr.201600862⟩
Journal articles hal-02624576v1

Modifying the infant's diet to prevent food allergy

Kate Grimshaw , Kirsty Logan , Sinead O'Donovan , Mairead Kiely , Karine Adel-Patient
Archives of Disease in Childhood, 2017, 102 (2), pp.179-186. ⟨10.1136/archdischild-2015-309770⟩
Journal articles hal-02619972v1
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Intragastric administration of Lactobacillus casei BL23 induces regulatory FoxP3+RORγt+ T cells subset in mice

Naima Bermudez , Daniel Lozano Ojalvo , Matieny Dite Aicha Maiga , Stéphane Hazebrouck , Karine Adel-Patient
Beneficial Microbes, 2017, ⟨10.3920/BM2016.0174⟩
Journal articles hal-01605163v1
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Heat processing of peanut seed enhances the sensitization potential of the major peanut allergen Ara h 6

Blanche Guillon , Hervé Bernard , Marie-Francoise Drumare , Stéphane Hazebrouck , Karine Adel-Patient
Molecular Nutrition and Food Research, 2016, 60 (12), pp.2722-2735. ⟨10.1002/mnfr.201500923⟩
Journal articles hal-02637546v1
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One-year oral toxicity study on a genetically modified maize MON810 variety in Wistar Han RCC rats (EU 7th Framework Programme project GRACE)

Dagmar Zeljenková , Radka Alacova , Júlia Ondrejková , Katarína Ambrušová , Mária Bartušová
Archives of Toxicology, 2016, 90 (10), ⟨10.1007/s00204-016-1798-4⟩
Journal articles hal-02639999v1

Assessment of IgE and IgG4 binding capacities of cow's milk proteins selectively altered by proteases

Alexandre Charcosset , Karine Adel-Patient , Christophe Dupont , Hervé Bernard
Journal of Agricultural and Food Chemistry, 2016, 64 (17), pp.3394 - 3404. ⟨10.1021/acs.jafc.5b01782⟩
Journal articles hal-02634004v1
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Allergies alimentaires: mécanismes, biomarqueurs et impact de différents facteurs environnementaux

Karine Adel-Patient
Innovations Agronomiques, 2016, 52, pp.1-14. ⟨10.15454/1.5133529105822612E12⟩
Journal articles hal-02630095v1

Non-IgE mediated food allergy

Daniel Lozano Ojalvo , Guillaume Lezmi , Naima Bermudez , Karine Adel-Patient
Drug Discovery Today: Disease Models, 2016, 17-18, pp.45-53. ⟨10.1016/j.ddmod.2016.09.003⟩
Journal articles hal-01602218v1
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Current challenges facing the assessment of the allergenic capacity of food allergens in animal models

Katrine Lindholm Bøgh , Jolanda van Bilsen , Robert Głogowski , Iván López-Expósito , Grégory Bouchaud
Clinical and Translational Allergy, 2016, 6 (1), ⟨10.1186/s13601-016-0110-2⟩
Journal articles hal-02639998v1
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Further studies on the biological activity of hazelnut allergens

Fany Blanc , Hervé Bernard , Sandrine Ah-Leung , Laetitia L. Przybylski-Nicaise , P. Stahl Skov
Clinical and Translational Allergy, 2015, 5 (1), ⟨10.1186/s13601-015-0066-7⟩
Journal articles hal-02634236v1

Épigénétique et allergie alimentaire

Karine Adel-Patient
Revue francaise d'allergologie, 2015, 55 (3), pp.121-122. ⟨10.1016/j.reval.2015.01.026⟩
Journal articles hal-02630868v1
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Influence of the route of exposure and the matrix on the sensitisation potency of a major cows’ milk allergen

Sophie Wavrin , Hervé Bernard , Jean-Michel J.-M. Wal , Karine Adel-Patient
Clinical and Translational Allergy, 2015, 5 (1), ⟨10.1186/s13601-015-0047-x⟩
Journal articles hal-02631090v1
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Allergenicity of peanut component Ara h 2: Contribution of conformational versus linear hydroxyproline-containing epitopes

Hervé Bernard , Blanche Guillon , Marie-Francoise Drumare , Evelyne Paty , Stephen C. Dreskin
Journal of Allergy and Clinical Immunology, 2015, 135 (5), pp.1267-1274. ⟨10.1016/j.jaci.2014.10.025⟩
Journal articles hal-02641509v1
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Goat's milk allergy without cow's milk allergy: suppression of non-cross-reactive epitopes on caprine beta-casein

Stéphane Hazebrouck , Sandrine Ah-Leung-Poullias , E. Bidat , E. Paty , Marie-Francoise Drumare
Clinical and Experimental Allergy, 2014, 44 (4), pp.602-610. ⟨10.1111/cea.12261⟩
Journal articles hal-02639662v1
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Ninety-day oral toxicity studies on two genetically modified maize MON810 varieties in Wistar Han RCC rats (EU 7th Framework Programme project GRACE)

Dagmar Zeljenková , Katarína Ambrušová , Mária Bartušová , Anton Kebis , Jevgenij Kovrižnych
Archives of Toxicology, 2014, 88 (12), pp.2289-2314. ⟨10.1007/s00204-014-1374-8⟩
Journal articles hal-02633370v1

Cutaneous or respiratory exposures to peanut allergens in mice and their impacts on subsequent oral exposure

Sophie Wavrin , Hervé Bernard , Jean-Michel J.-M. Wal , Karine Adel-Patient
International Archives of Allergy and Immunology, 2014, 164 (3), pp.189-199. ⟨10.1159/000363444⟩
Journal articles hal-02636778v1

Respiratory allergen from house dust mite is present in human milk and primes for allergic sensitization in a mouse model of asthma

Patricia Macchiaverni , Ahmed Rekima , Mathilde Turfkruyer , Laurent Mascarell , Sabi Airouche
Allergy, 2014, 69 (3), pp.395 - 398. ⟨10.1111/all.12332⟩
Journal articles hal-02637721v1
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Assessment of the sensitizing potential of processed peanut proteins in Brown Norway rats: roasting does not enhance allergenicity

Stine Kroghsbo , Neil M. Rigby , Philip E. Johnson , Karine Adel-Patient , Katrine L. Bogh
PLoS ONE, 2014, 9 (5), ⟨10.1371/journal.pone.0096475⟩
Journal articles hal-02635349v1

Peanut allergens are rapidly transferred in human breast milk and can prevent sensitization in mice

Hervé Bernard , Sandrine Ah Leung , Marie-Francoise Drumare , C. Feraudet-Tarisse , V. Verhasselt
Allergy, 2014, 69 (7), pp.888-897. ⟨10.1111/all.12411⟩
Journal articles hal-02631176v1

Production of human antibodies by in vitro immunization using a fusion protein containing the transcriptional transactivator of HIV-1

Mazhoura Ait Mebarek , A. Wijkhuisen , Karine Adel-Patient , P. Lamourette , M. Léonetti
Journal of Immunological Methods, 2013, 396 (1-2), pp.96-106. ⟨10.1016/j.jim.2013.07.015⟩
Journal articles hal-02649348v1

Immunomodulatory Potential of Partially Hydrolyzed beta-Lactoglobulin and Large Synthetic Peptides

Karine Adel-Patient , Sophie Nutten , Hervé Bernard , Rodolphe Fritsche , Sandrine Ah-Leung-Poullias
Journal of Agricultural and Food Chemistry, 2012, 60 (43), pp.10858 - 10866. ⟨10.1021/jf3031293⟩
Journal articles hal-02651963v1

Oral tolerance and Treg cells are induced in BALB/c mice after gavagewith bovine beta-lactoglobulin

Karine Adel-Patient , Sophie Wavrin , Hervé Bernard , Narimane Meziti , Sandrine Ah-Leung-Poullias
Allergy, 2011, 66 (10), pp.1312 - 1321. ⟨10.1111/j.1398-9995.2011.02653.x⟩
Journal articles hal-02646694v1

Regulatory T Cells Control Type I Food Allergy to Beta-Lactoglobulin in Mice

Reem Kanjarawi , Christophe Dercamp , Nathalie Etchart , Karine Adel-Patient , Jean-François Nicolas
International Archives of Allergy and Immunology, 2011, 156 (4), pp.387 - 396. ⟨10.1159/000323940⟩
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Boiling peanut Ara h 1 results in the formation of aggregates with reduced allergenicity

Fany Blanc , Yvonne M. Vissers , Karine Adel-Patient , Neil M. Rigby , Alan R. Mackie
Molecular Nutrition and Food Research, 2011, 55 (12), pp.1887 - 1894. ⟨10.1002/mnfr.201100251⟩
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Immunoglobulin-E-binding epitopes of wheat allergens in patients withfood allergy to wheat and in mice experimentally sensitized to wheat proteins

Sandra S. Denery-Papini , Marie Bodinier , Florence Pineau , Sylvie Triballeau , Olivier O. Tranquet
Clinical and Experimental Allergy, 2011, 41 (10), pp.1478 - 1492. ⟨10.1111/j.1365-2222.2011.03808.x⟩
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Effect of Heating and Glycation on the Allergenicity of 2S Albumins (Ara h 2/6) from Peanut

Yvonne M. Vissers , Fany Blanc , Per Stahl Skov , Phil E. Johnson , Neil M. Rigby
PLoS ONE, 2011, 6 (8), ⟨10.1371/journal.pone.0023998⟩
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Effect of roasting on the allergenicity of major peanut allergens Ara h 1 and Ara h 2/6: the necessity of degranulation assays

Y. M. Vissers , M. Iwan , Karine Adel-Patient , P. Stahl Skov , N. M. Rigby
Clinical and Experimental Allergy, 2011, 41 (11), pp.1631 - 1642. ⟨10.1111/j.1365-2222.2011.03830.x⟩
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Immunological and metabolomic impacts of administration of Cry1Ab protein and MON 810 maize in mouse

Karine Adel-Patient , Odette Guimaraes , Alain Paris , Marie-Francoise Drumare , Sandrine Ah-Leung-Poullias
PLoS ONE, 2011, 6 (1), pp.e16346. ⟨10.1371/journal.pone.0016346⟩
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Block Copolymers Have Differing Adjuvant Effects on the Primary Immune Response Elicited by Genetic Immunization and on Further Induced Allergy

Karine Adel-Patient , Laetitia Pothelune , Sandrine Ah-Leung , Jean-Michel Wal , Christophe Créminon
Clinical and Vaccine Immunology, 2010, 17 (1), pp. 36-42. ⟨10.1128/CVI.00275-09⟩
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In vitro digestion of Cry1Ab proteins and analysis of the impact on their immunoreactivity

Valeria Guimaraes , Marie-Francoise Drumare , Didier Lereclus , Michel Gohar , Patricia Lamourette
Journal of Agricultural and Food Chemistry, 2010, 58 (5), pp.3222-3231. ⟨10.1021/jf903189j⟩
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Allergy therapy by intranasal administration with recombinant Lactococcus lactis Producing bovine beta-lactoglobulin

Naima Bermudez , Sandrine Ah-Leung-Poullias , Luis Bermudez Humaran , Gerard Corthier , Philippe Langella
International Archives of Allergy and Immunology, 2009, 150 (1), pp.25-31. ⟨10.1159/000210377⟩
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Capacity of purified peanut allergens to induce degranulation in a functional in vitro assay: Ara h 2 and Ara h 6 are the most efficient elicitors

Fany Blanc , Karine Adel-Patient , M.-F. Drumare , E. Paty , J.-M. Wal
Clinical & Experimental Allergy, 2009, 39 (8), pp.1277-1285. ⟨10.1111/j.1365-2222.2009.03294.x⟩
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Allergic sensitization to bovine beta-lactoglobulin: comparison between germ-free and conventional BALB/c mice

Stéphane Hazebrouck , Laetitia L. Przybylski-Nicaise , Sandrine Ah-Leung-Poullias , Karine Adel-Patient , Gerard G. Corthier
International Archives of Allergy and Immunology, 2009, 148 (1), pp.65-72. ⟨10.1159/000151507⟩
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Influence of the route of administration on immunomodulatory properties of bovine beta-lactoglobulin-producing Lactobacillus casei

Stéphane Hazebrouck , Laetitia L. Przybylski-Nicaise , Sandrine Ah-Leung-Poullias , Karine Adel-Patient , Gerard G. Corthier
Vaccine, 2009, 27 (42), pp.5800-5805. ⟨10.1016/j.vaccine.2009.07.064⟩
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Sensitization and Elicitation of an Allergic Reaction to Wheat Gliadins in Mice

Marie Bodinier , Michael Leroy , Sandrine Ah-Leung , Fany Blanc , Olivier O. Tranquet
Journal of Agricultural and Food Chemistry, 2009, 57 (4), pp.1219-1225. ⟨10.1021/jf802898u⟩
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Update on optimized purification and characterization of natural milk allergens

Fany Blanc , Hervé Bernard , Stefano Alessandri , Merima Bublin , Evelyne Paty
Molecular Nutrition & Food Research, 2008, ⟨10.1002/mnfr.200700283⟩
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Animal models of food allergy. Application to wheat proteins

Marie Bodinier , Michael Leroy , Karine Adel-Patient
Revue Française d'Allergologie et d'Immunologie Clinique, 2008, 48 (8), pp.526-532. ⟨10.1016/j.allerg.2008.09.001⟩
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Current prophylactic and therapeutic uses of a recombinant lactococcus lactis strain secreting biologically active interleukin-12

Luis L. Bermudez Humaran , Naima G. Cortes-Perez , Sandrine Ah-Leung , Francois F. Lefèvre , Guang Yang
Journal of Molecular Microbiology and Biotechnology, 2008, 14 (1-3), pp.80-89. ⟨10.1159/000106086⟩
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Influence of the route of immunization and the nature of the bacterial vector on immunogenicity of mucosal vaccines based on lactic acid bacteria

Naima G. Cortes-Perez , Francois F. Lefèvre , Gerard G. Corthier , Karine Adel-Patient , Philippe P. Langella
Vaccine, 2007, 25 (36), pp.6581-6588. ⟨10.1016/j.vaccine.2007.06.062⟩
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Intranasal coadministration of live lactococci producing interleukin-12 and a major cow's milk allergen inhibits allergic reaction in mice

Naima Bermudez , Sandrine Ah-Leung-Poullias , Luis Bermudez Humaran , Gerard Corthier , Jean-Michel Wal
Clinical and Vaccine Immunology, 2007, 14 (3), pp.226-233. ⟨10.1128/CVI.00299-06⟩
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Constitutive delivery of bovine beta-lactoglobulin to the digestive tracts of gnotobiotic mice by engineered Lactobacillus casei

Stéphane Hazebrouck , Raish Oozeer , Karine Adel-Patient , Philippe P. Langella , Sylvie S. Rabot
Applied and Environmental Microbiology, 2006, 72 (12), pp.7460-7467. ⟨10.1128/AEM.01032-06⟩
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Oral administration of recombinant Lactococcus lactis expressing bovine beta-lactoglobulin partially prevents mice from sensitization

Karine Adel-Patient , Sandrine Ah-Leung , Christophe Créminon , Sébastien Nouaille , Jean-Marc J.-M. Chatel
Clinical and Experimental Allergy, 2005, 35 (4), pp.539-546. ⟨10.1111/j.1365-2222.2005.02225.x⟩
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Improvement of bovine beta-lactoglobulin production and secretion by Lactococcus lactis

Sébastien Nouaille , Luis L. Bermudez Humaran , Karine Adel-Patient , J. Commissaire , Alexandra A. Gruss
Brazilian Journal of Medical and Biological Research, 2005, 38 (3), pp.353-359. ⟨10.1590/S0100-879X2005000300005⟩
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Characterization of a Lactococcus lactis strain that secretes a major epitope of bovine β-lactoglobulin and evaluation of its immunogenicity in mice.-

Jean-Marc J.-M. Chatel , Sébastien Nouaille , Karine Adel-Patient , Yves Le Loir , Herman Boe
Applied and Environmental Microbiology, 2003, 69 (11), pp.6620-6627. ⟨10.1128/AEM.69.11.6620-6627.2003⟩
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Epitopic characterization of native bovine β-lactoglobulin

Gilles Clement , Didier Boquet , Yveline Frobert , Hervé Bernard , Luc Negroni
Journal of Immunological Methods, 2002, 266 (1-2), pp. 67-78. ⟨10.1016/S0022-1759(02)00149-7⟩
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