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Laetitia Dou

Researcher identifiers
  • IdHAL laetitia-dou
  • ResearcherId : Q-4963-2017
  • ORCID 0000-0002-4594-4676
  • Google Scholar :
  • IdRef : 253123275
  • ResearcherId :


**C2VN** *Centre de Recherche en CardioVasculaire et Nutrition* Aix-Marseille université, INSERM, INRAE


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Systematic Comparison of Uremic Toxin Removal Using Different Hemodialysis Modes: A Single-Center Crossover Prospective Observational Study

Ariane Duval-Sabatier , Stephane Burtey , Marion Pelletier , Manon Laforet , Laetitia Dou
Biomedicines, 2023, 11 (2), pp.373. ⟨10.3390/biomedicines11020373⟩
Journal articles hal-04391251v1
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Indoxyl sulfate inhibits muscle cell differentiation via Myf6/MRF4 and MYH2 downregulation

Stanislas Bataille , Nathalie Mckay , Laetitia Koppe , Alice Beau , Bérengère Benoit
Nephrology Dialysis Transplantation, 2023, ⟨10.1093/ndt/gfad123⟩
Journal articles hal-04254193v1

CD146 at the Interface between Oxidative Stress and the Wnt Signaling Pathway in Systemic Sclerosis

Xavier Heim , Julien Bermudez , Ahmad Joshkon , Elise Kaspi , Richard Bachelier
Journal of Investigative Dermatology, 2022, 142 (12), pp.3200-3210.e5. ⟨10.1016/j.jid.2022.03.038⟩
Journal articles hal-03922484v1

Neutrophil:lymphocyte ratio correlates with the uremic toxin indoxyl sulfate and predicts the risk of death in patients on hemodialysis

Guillaume Lano , Marion Sallée , Marion Pelletier , Stanislas Bataille , Megan Fraisse
Nephrology Dialysis Transplantation, 2022, 37 (12), pp.2528-2537. ⟨10.1093/ndt/gfab350⟩
Journal articles hal-03670071v1
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Protein/Fiber Index Modulates Uremic Toxin Concentrations in Hemodialysis Patients

Manon Ebersolt , Tacy Santana Machado , Cecilia Mallmann , Nathalie Mc-Kay , Laetitia Dou
Toxins, 2022, 14 (9), pp.589. ⟨10.3390/toxins14090589⟩
Journal articles hal-03922171v1
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Mechanisms of myostatin and activin A accumulation in chronic kidney disease

Stanislas Bataille , Laetitia Dou , Marc Bartoli , Marion Sallée , Julien Aniort
Nephrology Dialysis Transplantation, 2022, 37 (7), pp.1249-1260. ⟨10.1093/ndt/gfac136⟩
Journal articles hal-03670060v1
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Reversing endothelial dysfunction with empagliflozin to improve cardiomyocyte function in cardiorenal syndrome

Laetitia Dou , Stéphane Burtey
Kidney International, 2021, 99 (5), pp.1062-1064. ⟨10.1016/j.kint.2021.01.008⟩
Journal articles hal-03256334v1
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Aryl Hydrocarbon Receptor Activation and Tissue Factor Induction by Fluid Shear Stress and Indoxyl Sulfate in Endothelial Cells

Guillaume Lano , Manon Laforêt , Clarissa Von Kotze , Justine Perrin , Tawfik Addi
International Journal of Molecular Sciences, 2020, 21 (7), pp.2392. ⟨10.3390/ijms21072392⟩
Journal articles hal-02526006v1
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toxins Endothelial Toxicity of High Glucose and its by-Products in Diabetic Kidney Disease

Laetitia Dou , Noemie Jourde-Chiche
Toxins, 2019, 11 (10), pp.578. ⟨10.3390/toxins11100578⟩
Journal articles hal-02708220v1
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Mechanisms of tissue factor induction by the uremic toxin indole-3 acetic acid through aryl hydrocarbon receptor/nuclear factor-kappa B signaling pathway in human endothelial cells

Tawfik Addi , Stéphane Poitevin , Nathalie Mckay , Kamel Eddine El Mecherfi , Omar Kheroua
Archives of Toxicology, 2019, 93 (1), pp.121-136. ⟨10.1007/s00204-018-2328-3⟩
Journal articles hal-02060898v1

Endothelium structure and function in kidney health and disease

Noemie Jourde-Chiche , Fadi Fakhouri , Laetitia Dou , Jeremy Bellien , Stéphane Burtey
Nature Reviews Nephrology, 2019, 15 (2), pp.87-108. ⟨10.1038/s41581-018-0098-z⟩
Journal articles inserm-02160201v1

Aryl hydrocarbon receptor is activated in patients and mice with chronic kidney disease

Laetitia Dou , Stéphane Poitevin , Marion Sallée , Tawfik Addi , Bertrand Gondouin
Kidney International, 2018, 93 (4), pp.986-999. ⟨10.1016/j.kint.2017.11.010⟩
Journal articles hal-02060310v1
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Tryptophan-Derived Uremic Toxins and Thrombosis in Chronic Kidney Disease

Tawfik Addi , Laetitia Dou , Stéphane Burtey
Toxins, 2018, 10 (10), ⟨10.3390/toxins10100412⟩
Journal articles hal-02068080v1

The harmful effect of indoxyl sulfate on neovascularization in chronic kidney disease

Laetitia Dou , Stéphane Burtey
Kidney International, 2016, 89, pp.532-534. ⟨10.1016/j.kint.2015.12.030⟩
Journal articles hal-01464929v1

Plasma Xanthine Oxidase Activity Is Predictive of Cardiovascular Disease in Patients with Chronic Kidney Disease, Independently of Uric Acid Levels

Bertrand Gondouin , Noemie Jourde-Chiche , Marion Sallée , Laetitia Dou , Claire Cerini
Nephron Physiology, 2015, 131 (3), pp.167-174. ⟨10.1159/000441091⟩
Journal articles hal-01610424v1
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The Cardiovascular Effect of the Uremic Solute Indole-3 Acetic Acid

Laetitia Dou , Marion Sallée , Claire Cerini , Stéphane Poitevin , Bertrand Gondouin
Journal of the American Society of Nephrology, 2015, 26 (4), pp.876-887. ⟨10.1681/ASN.2013121283⟩
Journal articles hal-01610425v1
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The Aryl Hydrocarbon Receptor-Activating Effect of Uremic Toxins from Tryptophan Metabolism: A New Concept to Understand Cardiovascular Complications of Chronic Kidney Disease

Marion Sallée , Laetitia Dou , Claire Cerini , Stéphane Poitevin , Philippe Brunet
Toxins, 2014, 6 (3), pp.934-949. ⟨10.3390/toxins6030934⟩
Journal articles hal-01610428v1

Indolic uremic solutes increase tissue factor production in endothelial cells by the aryl hydrocarbon receptor pathway

Bertrand Gondouin , Claire Cerini , Laetitia Dou , Marion Sallée , Ariane Duval-Sabatier
Kidney International, 2013, 84 (4), pp.733-744. ⟨10.1038/ki.2013.133⟩
Journal articles hal-01610430v1

Vascular Incompetence in Dialysis Patients-Protein-Bound Uremic Toxins and Endothelial Dysfunction

Noemie Jourde-Chiche , Laetitia Dou , Claire Cerini , Francoise Dignat-George , Philippe Brunet
Seminars in Dialysis, 2011, 24 (3), pp.327-337. ⟨10.1111/j.1525-139X.2011.00925.x⟩
Journal articles hal-01610435v1

Does Uremia Cause Vascular Dysfunction?

Philippe Brunet , Bertrand Gondouin , Ariane Duval-Sabatier , Laetitia Dou , Claire Cerini
Kidney and Blood Pressure Research, 2011, 34 (4), pp.284-290. ⟨10.1159/000327131⟩
Journal articles hal-01610434v1

Transplanted Late Outgrowth Endothelial Progenitor Cells as Cell Therapy Product for Stroke

Chahrazad Moubarik , Benjamin Guillet , Bennis Youssef , Jean-Laurent Codaccioni , Marie-Dominique Piercecchi
Stem Cell Reviews and Reports, 2011, 7 (1), pp.208-220. ⟨10.1007/s12015-010-9157-y⟩
Journal articles hal-03670118v1

Determination of uremic solutes in biological fluids of chronic kidney disease patients by HPLC assay

Raymond Calaf , Claire Cerini , Cecile Genovesio , Pierre Verhaeghe , Noemie Jourde-Chiche
Journal of Chromatography B - Analytical Technologies in the Biomedical and Life Sciences, 2011, 879 (23), pp.2281-2286. ⟨10.1016/j.jchromb.2011.06.014⟩
Journal articles hal-01460285v1

Guanidino Compounds as Cause of Cardiovascular Damage in Chronic Kidney Disease: An in vitro Evaluation

Eva Schepers , Griet Glorieux , Laetitia Dou , Claire Cerini , Nathalie Gayrard
Blood Purification, 2010, 30 (4), pp.277-287. ⟨10.1159/000320765⟩
Journal articles hal-01610436v1

Protein-Bound Toxins-Update 2009

Noemie Jourde-Chiche , Laetitia Dou , Claire Cerini , Francoise Dignat-George , Raymond Vanholder
Seminars in Dialysis, 2009, 22 (4), pp.334-339. ⟨10.1111/j.1525-139X.2009.00576.x⟩
Journal articles hal-01610438v1

Levels of circulating endothelial progenitor cells are related to uremic toxins and vascular injury in hemodialysis patients

Noemie Jourde-Chiche , Laetitia Dou , Florence Sabatier , R. Calaf , Claire Cerini
Journal of Thrombosis and Haemostasis, 2009, 7 (9), pp.1576-1584. ⟨10.1111/j.1538-7836.2009.03540.x⟩
Journal articles hal-01610439v1

Circulating microparticles in renal diseases

Laurent Daniel , Laetitia Dou , Yvon Berland , Philippe Lesavre , Lise Mecarelli-Halbwachs
Nephrology Dialysis Transplantation, 2008, 23 (7), pp.2129-2132. ⟨10.1093/ndt/gfn029⟩
Journal articles hal-01610440v1

The uremic solute indoxyl sulfate induces oxidative stress in endothelial cells

Laetitia Dou , Noemie Jourde-Chiche , V. Faure , Claire Cerini , Yvon Berland
Journal of Thrombosis and Haemostasis, 2007, 5 (6), pp.1302-1308. ⟨10.1111/j.1538-7836.2007.02540.x⟩
Journal articles hal-01610441v1

Review on uraemic toxins III: recommendations for handling uraemic retention solutes in vitro towards a standardized approach for research on uraemia

G. Cohen , G. Glorieux , P. Thornalley , E. Schepers , N. Meert
Nephrology Dialysis Transplantation, 2007, 22 (12), pp.3381-3390. ⟨10.1093/ndt/gfm210⟩
Journal articles hal-03670130v1

Adsorption of the uremic toxin p-cresol onto hemodialysis membranes and microporous adsorbent zeolite silicalite

Véronique Wernert , Oliver Schäf , Valérie Faure , Philippe Brunet , Laetitia Dou
African Journal of Biotechnology, 2006, 123 (2), pp.164-173. ⟨10.1016/j.jbiotec.2005.11.009⟩
Journal articles hal-02011745v1

Elevation of circulating endothelial microparticles in patients with chronic renal failure

V Faure , Laetitia Dou , F Sabatier , Claire Cerini , J Sampol
Journal of Thrombosis and Haemostasis, 2006, 4 (3), pp.566-573. ⟨10.1111/j.1538-7836.2005.01780.x⟩
Journal articles hal-01610442v1

The uremic solutes p-cresol and indoxyl sulfate inhibit endothelial proliferation and wound repair

Laetitia Dou , E Bertrand , Claire Cerini , V Faure , J Sampol
Kidney International, 2004, 65 (2), pp.442-451. ⟨10.1111/j.1523-1755.2004.00399.x⟩
Journal articles hal-01610444v1

P-cresol, a uremic retention solute, alters the endothelial barrier function in vitro

Claire Cerini , Laetitia Dou , F Anfosso , F Sabatier , S Moal
Thrombosis and Haemostasis, 2004, 92 (1), pp.140-150. ⟨10.1160/th03-07-0491⟩
Journal articles hal-01610445v1

Impaired expression of glycoproteins on resting and stimulated platelets in uraemic patients

Valérie Moal , Philippe Brunet , Laetitia Dou , S Morange , J Sampol
Nephrology Dialysis Transplantation, 2003, 18 (9), pp.1834-1841. ⟨10.1093/ndt/gfg185⟩
Journal articles hal-01610446v1

Protein-bound uremic retention solutes

Philippe Brunet , Laetitia Dou , Claire Cerini , Yvon Berland
Advances in Renal Replacement Therapy, 2003, 10 (4), pp.310-320. ⟨10.1053/j.arrt.2003.08.002⟩
Journal articles hal-01610447v1

P-cresol, a uremic toxin, decreases endothelial cell response to inflammatory cytokines

Laetitia Dou , Claire Cerini , Philippe Brunet , C Guilianelli , V Moal
Kidney International, 2002, 62 (6), pp.1999-2009. ⟨10.1046/j.1523-1755.2002.t01-1-00651.x⟩
Journal articles hal-01610448v1

Effect of uremia and hemodialysis on soluble L-selectin and leukocyte surface CD11b and L-selectin

Laetitia Dou , Philippe Brunet , Francoise Dignat-George , J Sampol , Yvon Berland
American Journal of Kidney Diseases, 1998, 31 (1), pp.67-73. ⟨10.1053/ajkd.1998.v31.pm9428454⟩
Journal articles hal-01610449v1

Role of Kaposi's sarcoma cells in recruitment of circulating leukocytes: implications in pathogenesis

P Galea , V Frances , Laetitia Dou , J Sampol , J Chermann
Journal of Human Virology, 1998, 1 (4), pp.273-81
Journal articles hal-03670152v1

Système d'étude du comportement cellulaire en condition de flux

S Fabregues , Laetitia Dou , Francine Anfosso , Jean Fuseri , P Poncelet
Innovation et Technologie en Biologie et Medecine, ITBM, 1998, 19 (1), pp.43-50
Journal articles hal-03670200v1

Quantitative Analysis of Leukocyte Membrane Antigen Expression on Human Fetal and Cord Blood: Normal Values and Changes during Development

Arsène Bikoue , Claude d'Ercole , Françoise George , Laetitia Dameche , Murielle Mutin
Clinical immunology and immunopathology, 1997, 84 (1), pp.56-64. ⟨10.1006/clin.1997.4366⟩
Journal articles hal-03670166v1

Meltspun cellulose diacetate and polysulfone membranes have the same effect on complement activation and expression of leukocyte adhesion molecules and complement receptors

Laetitia Dameche , Philippe Brunet , Francoise Dignat-George , S Andre-Pinon , D Bernard
Nephrology Dialysis Transplantation, 1995, 10 (10), pp.33-38
Journal articles hal-01610451v1

Polymorphonuclear activation measured by surface expression of CD11b and CD62L in uremic patients.

Philippe Brunet , Laetitia Dou , Francoise Dignat-George , J Sampol , Yvon Berland
France. pp.A0313
Conference papers hal-01610450v1

Indole-3 acetic acid predicts cardiovascular event and mortality in chronic kidney disease patients: evidence for an endothelial inflammatory and prooxidant effect

Marion Sallée , Laetitia Dou , Claire Cerini , Stéphane Poitevin , Bertrand Gondouin
51st Congress of the European-Renal-Association(ERA)/European-Dialysis-and-Transplant-Association (EDTA), May 2014, Amsterdam, Netherlands. pp.163
Conference papers hal-01610429v1

Role of indole-derived uremic solutes on tissue factor production via aryl hydrocarbon receptor pathway

Claire Cerini , Bertrand Gondouin , Laetitia Dou , Ariane Duval-Sabatier , Philippe Brunet
49th Congress of the European-Renal-Association/European-Dialysis-and-Transplant-Association (ERA-EDTA), May 2012, Paris, France. pp.77
Conference papers hal-01610432v1

The uremic toxin indole-3-acetic acid induces endothelial cox-2 expression by increasing oxidative stress

Laetitia Dou , Bertrand Gondouin , Claire Cerini , Stéphane Poitevin , Philippe Brunet
49th Congress of the European-Renal-Association/European-Dialysis-and-Transplant-Association (ERA-EDTA), May 2012, Paris, France. pp.84
Conference papers hal-01610431v1

Elevation of endothelial microparticles in chronic renal failure: Role of uremic toxins

V Faure , Laetitia Dou , F Sabatier , Claire Cerini , J Sampol
42nd Annual Meeting of the European-Renal-Association/European-Dialysis-and-Transplant-Association (ERA-EDTA), Jun 2005, Istanbul, Turkey. pp.V63-V64
Conference papers hal-01610443v1