Laure Favot Laforge

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Publications

λ-CO, an oligosaccharide with anti-inflammatory properties

Clément Daviaud , Hugo Main , Damien Chassaing , Rachel Havret , Benjamin Musnier et al.

Biomedicine and Pharmacotherapy, 2026, 195, pp.118954. ⟨10.1016/j.biopha.2025.118954⟩

Article dans une revue hal-05468537v1
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Metabolism-based scoring of cutaneous squamous cell carcinoma to predict tumour features and responses to treatment with dihydroorotate dehydrogenase inhibitors

Lea Dousset , Ferial Khalife , Domitille Chalopin-Fillot , Benjamin Dartigues , Fatima Naji et al.

British Journal of Dermatology, 2025, 193 (5), pp.936-947. ⟨10.1093/bjd/ljaf253⟩

Article dans une revue hal-05338862v1

Energy metabolism rewiring following acute UVB irradiation is largely dependent on nuclear DNA damage

Léa Dousset , Walid Mahfouf , Hadi Younes , Hala Fatrouni , Corinne Faucheux et al.

Free Radical Biology and Medicine, 2025, 227, pp.459-471. ⟨10.1016/j.freeradbiomed.2024.12.030⟩

Article dans une revue hal-04894605v1

Heparanase 1 produced by keratinocytes contributes to psoriatic inflammation by promoting neutrophil infiltration

Hugo Main , Flavie Lobreau , Damien Chassaing , Sandrine Clarhault , Ewa Wierzbicka-Hainaut et al.

International Immunopharmacology, 2025, 167, pp.115742. ⟨10.1016/j.intimp.2025.115742⟩

Article dans une revue hal-05376775v1

Immune signatures across different stages of cutaneous squamous cell carcinoma

Laure Favot-Laforge , Elodie Muzotte , Walid Mahfouf , Jérome Rambert , Muriel Cario et al.

Journal of Dermatological Science, 2025, 118 (2), pp.79-82. ⟨10.1016/j.jdermsci.2025.03.002⟩

Article dans une revue hal-05442573v1
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The Pathophysiological Functions of Heparanases: From Evolution, Structural and Tissue‐Specific Perspectives

Elham Vahdatahar , Clément Daviaud , Hugo Main , Rachel Havret , Claire Debarnot et al.

FASEB Journal, 2025, 39 (17), ⟨10.1096/fj.202501859R⟩

Article dans une revue hal-05251863v1

TSLP and Nasal Epithelium: A Missing Link in Tezepelumab's Mechanism

Maxime Fieux , Yvan Bellanger , André Coste , Bruno Louis , Emilie Béquignon et al.

International Forum of Allergy and Rhinology, 2025, 15 (10), pp.1187-1188. ⟨10.1002/alr.70006⟩

Article dans une revue hal-05462770v1

Immunohistochemistry, Molecular Biology, and Clinical Scoring for the Detection of Muir-Torre Syndrome in Cutaneous Sebaceous Tumors: Which Strategy?

Hélinie Sinson , Lucie Karayan-tapon , Julie Godet , Pierre Rivet , Camille Alleyrat et al.

Dermatology, 2023, 239 (6), pp.889-897. ⟨10.1159/000534126⟩

Article dans une revue hal-04487948v1

Oncostatin M Contributes to Airway Epithelial Cell Dysfunction in Chronic Rhinosinusitis with Nasal Polyps

Florent Carsuzaa , Emilie Bequignon , Sophie Bartier , André Coste , Xavier Dufour et al.

International Journal of Molecular Sciences, 2023, 24 (7), pp.6094. ⟨10.3390/ijms24076094⟩

Article dans une revue hal-04185359v1
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Interleukin 34 exerts anti-inflammatory activities on keratinocytes and is down-regulated in psoriatic-inflamed skin

Magali Croquette , Alicia Faugeroux , Clémence Fonlupt , Julie Godet , Éric Frouin et al.

Journal of Investigative Dermatology, 2023, ⟨10.1016/j.jid.2023.05.023⟩

Article dans une revue hal-04133828v1

The M2 macrophages infiltration of sebaceous tumors is linked to the aggressiveness of tumors but not to the mismatch repair pathway

Eric Frouin , Camille Alleyrat , Julie Godet , Lucie Karayan-Tapon , Hélinie Sinson et al.

Journal of Cancer Research and Clinical Oncology, 2023, 149 (9), pp.6445-6454. ⟨10.1007/s00432-023-04629-x⟩

Article dans une revue hal-04185363v1

Cytokine Signature and Involvement in Chronic Rhinosinusitis with Nasal Polyps

Florent Carsuzaa , Émilie Béquignon , Xavier Dufour , Guillaume de Bonnecaze , Jean-Claude Lecron et al.

International Journal of Molecular Sciences, 2022, 23 (1), pp.417. ⟨10.3390/ijms23010417⟩

Article dans une revue hal-04185366v1
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IL-17 and IL-22 are pivotal cytokines to delay wound healing of S. aureus and P. aeruginosa infected skin

Jean-Claude Lecron , Sandrine Clarhaut-Charreau , Laure Favot-Laforge , Jean-François Jégou , Charles Bodet et al.

Frontiers in Immunology, 2022, 13, ⟨10.3389/fimmu.2022.984016⟩

Article dans une revue hal-04185385v1
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Oncostatin M Counteracts the Fibrotic Effects of TGF-β1 and IL-4 on Nasal-Polyp-Derived Fibroblasts: A Control of Fibrosis in Chronic Rhinosinusitis with Nasal Polyps?

Florent Carsuzaa , Émilie Béquignon , Matthieu Bainaud , Jean-François Jégou , Xavier Dufour et al.

International Journal of Molecular Sciences, 2022, 23 (11), pp.6308. ⟨10.3390/ijms23116308⟩

Article dans une revue hal-03801056v1
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Skin inflammatory response and efficacy of anti-epidermal growth factor receptor therapy in metastatic colorectal cancer (CUTACETUX)

David Tougeron , Sheik Emambux , Laure Favot , Thierry Lecomte , Ewa Wierzbicka-Hainaut et al.

OncoImmunology, 2020, 9 (1), pp.1848058. ⟨10.1080/2162402X.2020.1848058⟩

Article dans une revue hal-03149030v1
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Oncostatin M exerts a protective effect against excessive scarring by counteracting the inductive effect of TGFβ1 on fibrosis markers

Vincent Huguier , Jean-Philippe Giot , Marie Simonneau , Pierre Levillain , Sandrine Charreau et al.

Scientific Reports, 2019, 9 (1), pp.2113. ⟨10.1038/s41598-019-38572-0⟩

Article dans une revue hal-04184816v1
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Development of a new model of reconstituted mouse epidermis and characterization of its response to proinflammatory cytokines

Mathilde Pohin , Carolina Veaute , Julien Garnier , Christine Barrault , Laure Cronier et al.

Journal of Tissue Engineering and Regenerative Medicine, 2018, 12, pp.e1098- e1107. ⟨10.1002/term.2442⟩

Article dans une revue hal-01699562v1
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Oncostatin M is overexpressed in skin squamous-cell carcinoma and promotes tumor progression

Marie Simonneau , Eric Frouin , Vincent Huguier , Cynthia Jermidi , Jean François Jégou et al.

Oncotarget, 2018, 9 (92), pp.36457-36473. ⟨10.18632/oncotarget.26355⟩

Article dans une revue hal-04186396v1
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Liver fibrosis is associated with cutaneous inflammation in the imiquimod-induced murine model of psoriasiform dermatitis

P. Vasseur , M. Pohin , Jf. Jégou , L. Favot , N. Venisse et al.

British Journal of Dermatology, 2018, 179, pp.101-109. ⟨10.1111/bjd.16137⟩

Article dans une revue hal-01699551v1
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Persistent Neuroadaptations in the Expression of Genes Involved in Cholesterol Homeostasis Induced by Chronic, Voluntary Alcohol Intake in Rats

Josette Alsebaaly , Emilie Dugast , Laure Favot , Lydia Rabbaa Khabbaz , Marcello Solinas et al.

Frontiers in Molecular Neuroscience, 2018, 11, pp.457. ⟨10.3389/fnmol.2018.00457⟩

Article dans une revue inserm-02350853v1

VEGF-induced HUVEC migration and proliferation are decreased by PDE2 and PDE4 inhibitors

Laure Favot , Thérèse Keravis , Vincent Holl , Alain Le Bec , Claire Lugnier

Thrombosis and Haemostasis, 2017, 90 (08), pp.334-343. ⟨10.1160/TH03-02-0084⟩

Article dans une revue hal-04186086v1

Characterization of skin Th17 transcriptional profiles in psoriatic patients under adalimumab biotherapy

Amandine Buffière-Morgado , Elodie Couderc , Adriana Delwail , Laure Favot , Jean-François Jégou et al.

European Journal of Dermatology, 2017, ⟨10.1684/ejd.2017.3127⟩

Article dans une revue hal-01705097v1
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Interleukin-17A-induced production of acute serum amyloid A by keratinocytes contributes to psoriasis pathogenesis

Elodie Couderc , Franck Morel , Pierre Levillain , Amandine Buffière-Morgado , Magalie Camus et al.

PLoS ONE, 2017, 12 (7), pp.e0181486. ⟨10.1371/journal.pone.0181486⟩

Article dans une revue hal-01703911v1

Modulation of VEGF-induced endothelial cell cycle protein expression through cyclic AMP hydrolysis by PDE2 and PDE4

Laure Favot , Thérèse Keravis , Claire Lugnier

Thrombosis and Haemostasis, 2017, 92 (09), pp.634-645. ⟨10.1160/TH03-12-0768⟩

Article dans une revue hal-04186127v1

High-Fat Diet-Induced IL-17A Exacerbates Psoriasiform Dermatitis in a Mouse Model of Steatohepatitis

Philippe Vasseur , Laura Serres , Jean-Francois Jegou , Mathilde Pohin , Adriana Delwail et al.

American Journal of Pathology, 2016, 186 (9), pp.2292--2301. ⟨10.1016/j.ajpath.2016.05.012⟩

Article dans une revue hal-01390977v1
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Oncostatin M overexpression induces skin inflammation but is not required in the mouse model of imiquimod-induced psoriasis-like inflammation

Mathilde Pohin , William Guesdon , Andela Andrine Mekouo , Hanitriniaina Rabeony , Isabelle Petit-Paris et al.

European Journal of Immunology, 2016, 46 (7), pp.1737 - 1751. ⟨10.1002/eji.201546216⟩

Article dans une revue inserm-01701320v1

IL-17A EXACERBATES PSORIASIFORM DERMATITIS IN A MOUSE MODEL OF HIGH-FAT DIET-INDUCED STEATOHEPATITIS

J.-C. Lecron , P. Vasseur , L. Serres , J.-F. Jégou , M. Pohin et al.

Cytokine, 2016, 87, pp.51--51. ⟨10.1016/j.cyto.2016.07.020⟩

Article dans une revue istex hal-01485264v1

IMQ-induced skin inflammation in mice is dependent on IL-1R1 and MyD88 signaling but independent of the NLRP3 inflammasome

Hanitriniaina Rabeony , Mathilde Pohin , Philippe Vasseur , Isabelle Petit-Paris , Jean-François Jégou et al.

European Journal of Immunology, 2015, 45 (10), pp.2847 - 2857. ⟨10.1002/eji.201445215⟩

Article dans une revue hal-01702889v1
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Delphinidin inhibits tumor growth by acting on VEGF signalling in endothelial cells

T. Keravis , L. Favot , A.A. Abusnina , A. Anton , H. Justiniano et al.

PLoS ONE, 2015, 10 (12), pp.e0145291. ⟨10.1371/journal.pone.0145291⟩

Article dans une revue hal-01280466v1

Erratum: Loss of Environmental Enrichment Increases Vulnerability to Cocaine Addiction

Joelle Nader , Claudia Chauvet , Rana El Rawas , Laure Favot , Mohamed Jaber et al.

Neuropsychopharmacology, 2014, 39 (3), pp.780-780. ⟨10.1038/npp.2013.303⟩

Article dans une revue hal-04686832v1

Loss of Environmental Enrichment Increases Vulnerability to Cocaine Addiction

Joëlle Nader , Chauvet Claudia , Rana El Rawas , Laure Favot , Mohamed Jaber et al.

Neuropsychopharmacology, 2014, 37 (3), pp.1579-1587. ⟨10.1038/npp.2012.2⟩

Article dans une revue hal-04393339v1

Involvement of IL-1 and Oncostatin M in Acanthosis Associated With Hypertensive Leg Ulcer

Jean-Philippe Giot , Isabelle Petit-Paris , Pierre Levillain , Vincent Huguier , Sandrine Charreau et al.

American Journal of Pathology, 2013, 182 (3), pp.806 - 818. ⟨10.1016/j.ajpath.2012.11.030⟩

Article dans une revue hal-01703039v1

Design, synthesis and biological evaluation of new thalidomide analogues as TNF-alpha and IL-6 production inhibitors

Charlotte Chaulet , Cecile Croix , David Alagille , Sylvain Normand , Adriana Delwail et al.

Bioorganic and Medicinal Chemistry Letters, 2011, 21 (3), pp.1019-1022. ⟨10.1016/j.bmcl.2010.12.031⟩

Article dans une revue istex hal-00610445v1

Specific increase in caspase-1 activity and secretion of IL-1 family cytokines: a putative link between mevalonate kinase deficiency and inflammation

Sylvain Normand , Benoit Massonnet , Adriana Delwail , Laure Favot , Laurence Cuisset et al.

European Cytokine Network, 2009, 20 (3), pp.101-107. ⟨10.1684/ecn.2009.0163⟩

Article dans une revue (article de synthèse) hal-04927562v1

Pharmacological inhibitors of the mevalonate pathway activate pro-IL-1 processing and IL-1 release by human monocytes.

Benoit Massonnet , Sylvain Normand , Reinhard Moschitz , Adriana Delwail , Laure Favot et al.

European citokine Network, 2009, 20 (3), pp.112-120. ⟨10.1684/ecn.2009.0162⟩

Article dans une revue hal-00466975v1

Cytoplasmic YY1 Is Associated with Increased Smooth Muscle-Specific Gene Expression

Laure Favot , Susan Hall , Sheila Haworth , Paul Kemp

American Journal of Pathology, 2005, 167 (6), pp.1497-1509. ⟨10.1016/S0002-9440(10)61236-9⟩

Article dans une revue hal-04186093v1

Overexpression of a family of RPEL proteins modifies cell shape

Laure Favot Laforge , Marc Gillingwater , Caroline Scott , Paul Kemp

FEBS Letters, 2005, 579 (1), pp.100-104. ⟨10.1016/j.febslet.2004.11.054⟩

Article dans une revue hal-04186122v1

Involvement of cyclin-dependent pathway in the inhibitory effect of delphinidin on angiogenesis

L. Favot , S. Martin , T. Keravis , R. Andriantsitohaina , C. Lugnier

Cardiovascular Research, 2003, 59 (2), pp.479-487. ⟨10.1016/s0008-6363(03)00433-4⟩

Article dans une revue hal-02463117v1

Delphinidin inhibits endothelial cell proliferation and cell cycle progression through a transient activation of ERK-1/-2

Sophie Martin , Laure Favot , Rachel Matz , Claire Lugnier , Ramaroson Andriantsitohaina

Biochemical Pharmacology, 2003, 65 (4), pp.669-675. ⟨10.1016/S0006-2952(02)01568-X⟩

Article dans une revue istex hal-02463110v1

Cyclic Nucleotide Phosphodiesterases in Health and Disease

Joseph Beavo , Sharron Francis , Miles Houslay , L. Favot

Cyclic Nucleotide Phosphodiesterases in Health and Disease, 1, CRC Press, 2006, ⟨10.1201/9781420020847⟩

Chapitre d'ouvrage hal-05462842v1