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laurent Micouin
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Documents
Présentation
MICOUIN Laurent
CNRS Research Director first class, UMR 8601 Paris Descartes
Laboratoire de Chimie et de Biochimie pharmacologiques et toxicologiques
45, rue des Saints Pères, 75006 Paris, France
Phone + (33) 1 42 86 20 40, Fax + (33) 1 42 86 83 87
e-mail : laurent.micouin@parisdescartes.fr
Born on March 6th 1968, Clermont Ferrand, France
Academic and Professional Background :
2014- CNRS Research Director, first class (UMR 8601, University Paris Descartes)
2012-2014 CNRS Research Director, second class (UMR 8601, University Paris Descartes)
2005-2012 CNRS Research Director, second class (UMR 8638, University Paris Descartes)
2000-2005 CNRS Associate Scientist, first class (UMR 8638, University Paris Descartes)
2000 Habilitation, University Paris Descartes, Paris, France
1996-2000 CNRS Associate Scientist, second class (UMR 8638, University Paris Descartes)
1995- 1996 Post-Doctoral Fellow, University Marburg, Germany (with Prof. P.Knochel)
1992-1995 PhD in Chemistry, University Paris 5 (with Prof. J.-C. Quirion and Prof. H.-P. Husson)
1990-1992 Research Assistant, Institut Malardé, French Polynesia
1990 Master in Chemistry, University Paris 6 (With Prof. P. Cresson)
1990 Engineer in Chemistry, ENSCP (Chemistry National School), Paris.
**Scientific Record:**
96 publications, 8 patents, book chapters, 1 book co-editor (Patai), 66 invited conferences or seminars
**Scientific interests**
\- Diversity-oriented synthesis of bioactive compounds or tools for biological investigations.
\- New chemical methods for the fragment-based synthesis of RNA binders
\- New synthetic methods for the preparation of organoaluminum reagents
**Official capacities**
2019-
2016-
2015-2018
2012-2018
2011- 2013
2010- 2012
Director of UMR 8601
Member of the CNRS national Committee (section 16).
CNRS Deputy director of UMR 8601
Head of the Doctoral School 563 MTCI "Medecines, Toxicology, Chemistry, Imaging), board member of several doctoral schools.
CNRS Scientific Officer (chargé de mission), National Chemistry Institute, CNRS Deputy director of UMR 8638
**Honors and awards**
2007 Invited Professor (Puebla University, Mexico)
2005 French Chemical Society Acros prize
1996 Roussel (PhD) prize of Paris 5 University
1995 Alexander Von Humboldt post-doctoral fellowship
Publications
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Fragment-based design of small RNA binders: promising developments and contribution of NMR.Biochimie, 2012, 94 (7), pp.1607-1619. ⟨10.1016/j.biochi.2012.02.002⟩
Article dans une revue
hal-00692356v1
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Investigation of RNA-Ligand Interactions by (19) F NMR Spectroscopy Using Fluorinated Probes.Angewandte Chemie International Edition, 2012, 51 (38), pp.9530-9534. ⟨10.1002/anie.201204083⟩
Article dans une revue
hal-00724894v1
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Tether influence on the binding properties of tRNALys3 ligands designed by a fragment-based approach.Organic & Biomolecular Chemistry, 2010, 8 (5), pp.1154-9. ⟨10.1039/b921232a⟩
Article dans une revue
hal-00596199v1
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