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Luc Maroteaux

CV Luc Maroteaux
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**CURRICULUM VITAE** n **Nom, prénom :** MAROTEAUX, Luc **Date et lieu de naissance:** 14 Septembre 1955, Versailles, France **Grade :** Directeur de Recherche 1° Classe Emérite CNRS **Adresse Professionnelle :** INSERM U839-U1270 Institut du Fer à Moulin Rue du Fer à Moulin 75005 PARIS **Email :** **Tel :** 33 (0) **Fax :** 33 (0) **DEROULEMENT DE CARRIERE** 1976-1980 : Ecole Normale Supérieure St Cloud 1979 : DEA de Biologie Moléculaire - Univ.L. Pasteur Strasbourg. Biologie Moléculaire (P. Chambon) Séquence et identification de la première "TATA BOX" eucaryote. 1981-1983 : stage pré doctoral (laboratoire du Pr. M. Revel) Institut Weissman - Israël Clonage des interférons humains alpha et beta. 1984 : Thèse d'état en Biologie Moléculaire (Pr P. Chambon) - Université L. Pasteur - Strasbourg: Etude de la régulation de la transcription de l'interféron beta1 humain. 1984-1985 : Chargé de recherches 2° classe CNRS - Banyuls sur Mer. 1985-1987 : Chargé de recherches 2° classe CNRS - Banyuls sur Mer. Clonage des gènes ribosomiques de Dinoflagellés- Evolution moléculaire. 1987-1989 : Post-doctorat- en neurobiologie moléculaire (laboratoire R. Scheller) Université de Stanford, USA. Clonage et caractérisation des synucléines. 1989-1993 : Chargé de recherches 1° classe CNRS - Laboratoire du Pr P. Chambon - Strasbourg. Clonage de nouveaux GPCRs. 1993 : Directeur de recherches 2° classe CNRS - direction d'un groupe de recherche sur le rôle morphogène de la sérotonine à l’IGBMC Strasbourg. 2001 : Directeur de recherches 1° classe - CNRS à l’IGBMC Strasbourg. 2004: Mutation à Paris, Création de l’U616 Inserm Sérotonine et développement 2007: Création de l’U839 Inserm-Institut du Fer à Moulin Responsable de l'équipe 5 " Signalisation de la sérotonine dans la plasticité et la pathologie" 2019: Renouvellement-création de l’U1270 Inserm-Institut du Fer à Moulin Responsable de l'équipe 5 " Sérotonine, microglie, plasticité et la pathologie"

Research domains



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5-HT1A and 5-HT2B receptor interaction and co-clustering regulate serotonergic neuron excitability

Amina Benhadda , Célia Delhaye , Imane Moutkine , Xavier Marques , Marion Russeau
iScience, 2023, 26 (8), pp.107401. ⟨10.1016/j.isci.2023.107401⟩
Journal articles hal-04196168v1
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First quantitative dosages: Strong correlations between non-5-HT2Rs serotonin receptors on normal human heart valves

Olivier Schussler , Luc Maroteaux , Ramadan Jashari , Pierre Falcoz , Marco Alifano
Frontiers in Cardiovascular Medicine, 2022, 9, pp.897657. ⟨10.3389/fcvm.2022.897657⟩
Journal articles hal-03867505v1
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Serotonin 2B Receptor by Interacting with NMDA Receptor and CIPP Protein Complex May Control Structural Plasticity at Glutamatergic Synapses

Amina Benhadda , Emily Quentin , Imane Moutkine , Benjamin Chanrion , Marion Russeau
ACS Chemical Neuroscience, 2021, ⟨10.1021/acschemneuro.0c00638⟩
Journal articles hal-03176117v1
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Targeting 5-HT 2B Receptor Signaling Prevents Border Zone Expansion and Improves Microstructural Remodeling after Myocardial Infarction

J Caleb Snider , Lance A Riley , Noah T Mallory , Matthew R Bersi , Prachi Umbarkar
Journal articles hal-03121681v1
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The serotonin 2B receptor is required in neonatal microglia to limit neuroinflammation and sickness behavior in adulthood

Catherine Béchade , Ivana d'Andrea , Fanny Etienne , Franck Verdonk , Imane Moutkine
Journal articles hal-02978295v1
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A positive association between a polymorphism in the HTR2B gene and cocaine-crack in a French Caribbean population

Jérôme Lacoste , Sandrine Lamy , Nicolas Ramoz , Nicolas Ballon , Louis Jehel
World Journal of Biological Psychiatry, 2020, 21 (10), pp.784-789. ⟨10.1080/15622975.2018.1563721⟩
Journal articles hal-01971860v1
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International Union of Basic and Clinical Pharmacology. CX. Classification of Receptors for 5-hydroxytryptamine; Pharmacology and Function

Nicholas M Barnes , Gerard P Ahern , Carine Becamel , Joël Bockaert , Michael Camilleri
Pharmacological Reviews, 2020, 73 (1), pp.310-520. ⟨10.1124/pr.118.015552⟩
Journal articles hal-03099832v1
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Serotonin (5-HT) Shapes the Macrophage Gene Profile through the 5-HT2B –Dependent Activation of the Aryl Hydrocarbon Receptor

Concha Nieto , Ignacio Rayo , Mateo de Las Casas-Engel , Elena Izquierdo , Bárbara Alonso
Journal of Immunology, 2020, pp.ji1901531. ⟨10.4049/jimmunol.1901531⟩
Journal articles hal-02544960v1
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Evolutionary considerations on 5-HT2 receptors

Imane Moutkine , Emily Lauren Collins , Catherine Béchade , Luc Maroteaux
Pharmacological Research, 2019, 140, pp.14-20. ⟨10.1016/j.phrs.2018.09.014⟩
Journal articles hal-01890665v1
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Dimers of serotonin receptors: impact on ligand affinity and signaling

Luc Maroteaux , Catherine Béchade , Anne Roumier
Biochimie, 2019, 161, pp.23-33. ⟨10.1016/j.biochi.2019.01.009⟩
Journal articles hal-01996206v1
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Regulation of raphe serotonin neurons by serotonin 1A and 2B receptors

Arnauld Belmer , Luc Maroteaux
Neuropsychopharmacology, 2019, 44 (1), pp.218-219. ⟨10.1038/s41386-018-0214-6⟩
Journal articles hal-01890660v1
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Enhanced Renewal of Erythroid Progenitors in Myelodysplastic Anemia by Peripheral Serotonin

David Sibon , Tereza Coman , Julien Rossignol , Mathilde Lamarque , Olivier Kosmider
Cell Reports, 2019, 26 (12), pp.3246-3256.e4. ⟨10.1016/j.celrep.2019.02.071⟩
Journal articles hal-02086600v1
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Two-photon Imaging of Microglial Processes' Attraction Toward ATP or Serotonin in Acute Brain Slices

Fanny Etienne , Vincenzo Mastrolia , Luc Maroteaux , Jean‐antoine Girault , Nicolas Gervasi
Journal of visualized experiments : JoVE, 2019, 143, ⟨10.3791/58788⟩
Journal articles hal-02348070v1
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Morphine withdrawal recruits lateral habenula cytokine signaling to reduce synaptic excitation and sociability

Kristina Valentinova , Anna Tchenio , Massimo Trusel , Joseph Clerke , Arnaud Lalive
Nature Neuroscience, 2019, 22 (7), pp.1053-1056. ⟨10.1038/s41593-019-0421-4⟩
Journal articles hal-02348080v1
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Adiporon, an adiponectin receptor agonist acts as an antidepressant and metabolic regulator in a mouse model of depression

Sarah Nicolas , Delphine Debayle , Catherine Béchade , Luc Maroteaux , Anne-Sophie Gay
Translational Psychiatry, 2018, 8 (1), pp.159. ⟨10.1038/s41398-018-0210-y⟩
Journal articles inserm-02438258v1
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Frontiers of Serotonin Beyond the Brain

Luc Maroteaux , Fusun Kilic
Pharmacological Research, 2018, 140, pp.1-6. ⟨10.1016/j.phrs.2018.10.022⟩
Journal articles hal-01915456v1
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Adiporon, an adiponectin receptor agonist acts as an antidepressant and metabolic regulator in a mouse model of depression

Sarah Nicolas , Delphine Debayle , Catherine Béchade , Luc Maroteaux , Anne-Sophie Gay
Translational Psychiatry, 2018, 8, pp.159. ⟨10.1038/s41398-018-0210-y⟩
Journal articles hal-01868962v1
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Positive regulation of raphe serotonin neurons by serotonin 2B receptors

Arnauld Belmer , Emily Quentin , Silvina L. Diaz , Bruno Guiard , Sebastian P Fernandez
Neuropsychopharmacology, 2018, 43 (7), pp.1623-1633. ⟨10.1038/s41386-018-0013-0⟩
Journal articles hal-01703916v1
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Translational studies support a role for serotonin 2B receptor (HTR2B) gene in aggression-related cannabis response

Janitza L Montalvo-Ortiz , Hang Zhou , Ivana D 'Andrea , Luc Maroteaux , Adriana Lori
Molecular Psychiatry, 2018, 23 (12), pp.2277-2286. ⟨10.1038/s41380-018-0077-6⟩
Journal articles hal-01825924v1
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Somato-Dendritic Regulation of Raphe Serotonin Neurons; A Key to Antidepressant Action

Emily Quentin , Arnauld Belmer , Luc Maroteaux
Frontiers in Neuroscience, 2018, 12, pp.982. ⟨10.3389/fnins.2018.00982⟩
Journal articles hal-01980026v2
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Serotonergic 5-HT 2B receptors in mitral valvulopathy: bone marrow mobilization of endothelial progenitors

Estelle Ayme-Dietrich , Roland Lawson , Francine Côté , Claudia de Tapia , Sylvia da Silva
British Journal of Pharmacology, 2017, ⟨10.1111/bph.13981⟩
Journal articles hal-01593837v1

Serotonin transporter protects the placental cells against apoptosis in caspase 3-independent pathway

Coedy Hadden , Tariq Fahmi , Anthonya Cooper , Alena V. Savenka , Vladimir V. Lupashin
Journal of Cellular Physiology, 2017, 232 (12), pp.3520 - 3529. ⟨10.1002/jcp.25812⟩
Journal articles hal-01593857v1

Cardiovascular remodeling and the peripheral serotonergic system

Estelle Ayme-Dietrich , Gaëlle Aubertin-Kirch , Luc Maroteaux , Laurent Monassier
Archives of cardiovascular diseases, 2017, 110 (1), pp.51 - 59. ⟨10.1016/j.acvd.2016.08.002⟩
Journal articles hal-01593856v1
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Serotonin 2B receptors in mesoaccumbens dopamine pathway regulate cocaine responses

Stephane Doly , Emily Quentin , Raphaël Eddine , Stefania Tolu , Sebastian P Fernandez
Journal of Neuroscience, 2017, 37 (43), pp.10372-10388. ⟨10.1523/JNEUROSCI.1354-17.2017⟩
Journal articles hal-01593826v1
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Adaptive Control of Dorsal Raphe by 5-HT4 in the Prefrontal Cortex Prevents Persistent Hypophagia following Stress

Alexandra Jean , Laetitia Laurent , Sabira Delaunay , Stéphane Doly , Nicole Dusticier
Cell Reports, 2017, 21 (4), pp.901-909. ⟨10.1016/j.celrep.2017.10.003⟩
Journal articles hal-01667516v1
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Heterodimers of serotonin receptor subtypes 2 are driven by 5-HT 2C protomers

Imane Moutkine , Emily Quentin , Bruno P. Guiard , Luc Maroteaux , Stephane Doly
Journal of Biological Chemistry, 2017, 292 (15), pp.6352-6368. ⟨10.1074/jbc.M117.779041⟩
Journal articles hal-01593841v1
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New therapeutic opportunities for 5-HT2 receptor ligands

Luc Maroteaux , Estelle Ayme-Dietrich , Gaëlle Aubertin-Kirch , Sophie Banas , Emily Quentin
Pharmacology and Therapeutics, 2017, 170, pp.14 - 36. ⟨10.1016/j.pharmthera.2016.10.008⟩
Journal articles hal-01387994v1
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Hypertension artérielle pulmonaire, moelle osseuse, précurseurs endothéliaux et sérotonine

Estelle Ayme-Dietrich , Sophie M. Banas , Laurent Monassier , Luc Maroteaux
Biologie Aujourd'hui, 2016, 210 (2), pp.79-88. ⟨10.1051/jbio/2016012⟩
Journal articles hal-01593852v1
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Discrepancy in insulin regulation between GDM-platelets and -placenta

Yicong Li , Anthonya Cooper , Imelda N Odibo , Asli Ahmed , Pamela Murphy
Journal of Biological Chemistry, 2016, ⟨10.1074/jbc.M116.713693⟩
Journal articles hal-01280557v1
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Serotonin 2B receptor slows disease progression and prevents degeneration of spinal cord mononuclear phagocytes in amyotrophic lateral sclerosis.

Hajer El Oussini , Hanna Bayer , Jelena Scekic-Zahirovic , Pauline Vercruysse , Jérôme Sinniger
Acta Neuropathologica, 2016, 131 (3), pp.465-480. ⟨10.1007/s00401-016-1534-4⟩
Journal articles hal-01253857v1
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Serotonin Modulates Developmental Microglia via 5-HT2B Receptors: Potential Implication during Synaptic Refinement of Retinogeniculate Projections.

M Kolodziejczak , C Béchade , N Gervasi , T Irinopoulou , Sm Banas
ACS Chemical Neuroscience, 2015, 6 (7), pp.1219-1230. ⟨10.1021/cn5003489⟩
Journal articles hal-01224546v1
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Mice lacking the serotonin 5-HT2B receptor as an animal model of resistance to selective serotonin reuptake inhibitors antidepressants.

Silvina Laura Diaz , Nicolas Narboux-Nême , Katia Boutourlinsky , Stéphane Doly , Luc Maroteaux
European Neuropsychopharmacology, 2015, 26 (2), pp.265-279. ⟨10.1016/j.euroneuro.2015.12.012⟩
Journal articles hal-01253863v1
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Mice Lacking the Serotonin Htr2B Receptor Gene Present an Antipsychotic-Sensitive Schizophrenic-Like Phenotype.

Pothitos M Pitychoutis , Arnauld Belmer , Imane Moutkine , Joëlle Adrien , Luc Maroteaux
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology., 2015, 40 (12), pp.2764-73. ⟨10.1038/npp.2015.126⟩
Journal articles inserm-01149629v1
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Commentary: Chronic SSRI stimulation of astrocytic 5-HT2B receptors change multiple gene expressions/editings and metabolism of glutamate, glucose and glycogen: a potential paradigm shift

Sophie M. Banas , Silvina L. Diaz , Stéphane Doly , Arnauld Belmer , Luc Maroteaux
Frontiers in Behavioral Neuroscience, 2015, 9, pp.207. ⟨10.3389/fnbeh.2015.00207⟩
Journal articles hal-01225050v2

Contribution of serotonin to cardiac remodeling associated with hypertensive diastolic ventricular dysfunction in rats

Estelle Ayme-Dietrich , Halim Marzak , Roland Lawson , Walid Mokni , Olivia Wendling
Journal of Hypertension, 2015, 33 (11), pp.2310 - 2321. ⟨10.1097/HJH.0000000000000695⟩
Journal articles hal-01593863v1
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Role of the N-terminal region in G protein-coupled receptor functions: negative modulation revealed by 5-HT2B receptor polymorphisms.

Arnauld Belmer , Stephane Doly , Vincent Setola , Sophie M. Banas , Imane Moutkine
Molecular Pharmacology, 2014, 85 (1), pp.127-38. ⟨10.1124/mol.113.089086⟩
Journal articles inserm-00996746v1
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GDM-associated insulin deficiency hinders the dissociation of SERT from ERp44 and down-regulates placental 5-HT uptake.

Yicong Li , Coedy Hadden , Preeti Singh , Charles P Mercado , Pamela Murphy
Proceedings of the National Academy of Sciences of the United States of America, 2014, 111 (52), pp.E5697-705. ⟨10.1073/pnas.1416675112⟩
Journal articles hal-01225032v1
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A serotonin-induced N-glycan switch regulates platelet aggregation.

Charles P. Mercado , Maritza V. Quintero , Yicong Li , Preeti Singh , Alicia K. Byrd
Scientific Reports, 2013, 3, pp.2795. ⟨10.1038/srep02795⟩
Journal articles inserm-00996761v1
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Overexpression of 5-hydroxytryptamine 2B receptor gene in pulmonary hypertension: still a long way to understand its transcriptional regulation.

Luc Maroteaux
Hypertension, 2013, 61 (4), pp.e28-9. ⟨10.1161/HYPERTENSIONAHA.111.00702⟩
Journal articles inserm-00996750v1
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Paradoxical increase in survival of newborn neurons in the dentate gyrus of mice with constitutive depletion of serotonin.

Silvina L. Diaz , Nicolas Narboux-Nême , Sara Trowbridge , Sophie Scotto-Lomassese , Felix B. Kleine Borgmann
European Journal of Neuroscience, 2013, 38 (5), pp.2650-8. ⟨10.1111/ejn.12297⟩
Journal articles inserm-00996749v1
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Serotonin 5-HT2B receptors are required for bone-marrow contribution to pulmonary arterial hypertension.

Jean-Marie Launay , Philippe Hervé , Jacques Callebert , Ziad Mallat , Corinne Collet
Blood, 2012, 119 (7), pp.1772-80. ⟨10.1182/blood-2011-06-358374⟩
Journal articles inserm-00996752v1
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5-HT(2B) receptors are required for serotonin-selective antidepressant actions.

Silviana Laura Diaz , Stéphane Doly , Nicolas Narboux-Nême , Sébasatien Fernández , Pierre Mazot
Molecular Psychiatry, 2012, 17 (2), pp.154-63. ⟨10.1038/mp.2011.159⟩
Journal articles inserm-00652573v1
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Serotonin 2B receptor (5-HT2B R) signals through prostacyclin and PPAR-ß/δ in osteoblasts.

Yasmine Chabbi-Achengli , Jean-Marie Launay , Luc Maroteaux , Marie Christine de Vernejoul , Corinne Collet
PLoS ONE, 2012, 8 (9), pp.e75783. ⟨10.1371/journal.pone.0075783⟩
Journal articles hal-01225060v1
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Anti-nociceptive effect of peripheral serotonin 5-HT2B receptor activation on neuropathic pain.

Nataliya Urtikova , Nadège Berson , Juliette van Steenwinckel , Stéphane Doly , Jérémy Truchetto
Pain, 2012, 153 (6), pp.1320-31. ⟨10.1016/j.pain.2012.03.024⟩
Journal articles hal-01225065v1
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Deconstructing Antiobesity Compound Action: Requirement of Serotonin 5-HT(2B) Receptors for Dexfenfluramine Anorectic Effects.

Sophie M. Banas , Stéphane Doly , Katia Boutourlinsky , Silvina L. Diaz , Arnauld Belmer
Neuropsychopharmacology, 2011, 36 (2), pp.423-33. ⟨10.1038/npp.2010.173⟩
Journal articles hal-00583533v2
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Implication of 5-HT(2B) receptors in the serotonin syndrome.

Silvina Laura Diaz , Luc Maroteaux
Neuropharmacology, 2011, 61 (3), pp.495-502. ⟨10.1016/j.neuropharm.2011.01.025⟩
Journal articles inserm-00561473v1
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Stimulating healthy tissue regeneration by targeting the 5-HT₂B receptor in chronic liver disease.

Mohammad R. Ebrahimkhani , Fiona Oakley , Lindsay B. Murphy , Jelena Mann , Anna Moles
Nature Medicine, 2011, 17 (12), pp.1668-73. ⟨10.1038/nm.2490⟩
Journal articles inserm-00652584v1
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Platelet-derived serotonin links vascular disease and tissue fibrosis.

Clara Dees , Alfiya Akhmetshina , Pawel Zerr , Nicole Reich , Katrin Palumbo
Journal of Experimental Medicine, 2011, 208 (5), pp.961-972. ⟨10.1084/jem.20101629⟩
Journal articles inserm-00589662v1

Lack of serotonin 5-HT2B receptor alters proliferation and network volume of interstitial cells of Cajal in vivo.

V. S. Tharayil , M. M. Wouters , J. E. Stanich , J. L. Roeder , S. Lei
Neurogastroenterology & Motility, 2010, 22 (4), pp.462-9, e109-10. ⟨10.1111/j.1365-2982.2009.01435.x⟩
Journal articles inserm-00996753v1
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Contribution of gene-modified mice and rats to our understanding of the cardiovascular pharmacology of serotonin.

Laurent Monassier , Marc André Laplante , Tarak Ayadi , Stéphane Doly , Luc Maroteaux
Pharmacology and Therapeutics, 2010, 128 (3), pp.559-67. ⟨10.1016/j.pharmthera.2010.08.004⟩
Journal articles inserm-00549197v2
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A population-specific HTR2B stop codon predisposes to severe impulsivity.

Laura Bevilacqua , Stéphane Doly , Jaakko Kaprio , Qiaoping Yuan , Roope Tikkanen
Nature, 2010, 468 (7327), pp.1061-6. ⟨10.1038/nature09629⟩
Journal articles inserm-00550376v1
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Serotonin and angiotensin receptors in cardiac fibroblasts coregulate adrenergic-dependent cardiac hypertrophy.

Fabrice Jaffré , Philippe Bonnin , Jacques Callebert , Haythem Debbabi , Vincent Setola
Circulation Research, 2009, 104 (1), pp.113-23. ⟨10.1161/CIRCRESAHA.108.180976⟩
Journal articles inserm-00484528v1
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Role of serotonin via 5-HT2B receptors in the reinforcing effects of MDMA in mice.

Stéphane Doly , Jesus Bertran-Gonzalez , Jacques Callebert , Alexandra Bruneau , Sophie Marie Banas
PLoS ONE, 2009, 4 (11), pp.e7952. ⟨10.1371/journal.pone.0007952⟩
Journal articles inserm-00484504v1
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Serotonin 5-HT2B receptors are required for 3,4-methylenedioxymethamphetamine-induced hyperlocomotion and 5-HT release in vivo and in vitro.

Stéphane Doly , Emmanuel Valjent , Vincent Setola , Jacques Callebert , Denis Hervé
Journal of Neuroscience, 2008, 28 (11), pp.2933-40. ⟨10.1523/JNEUROSCI.5723-07.2008⟩
Journal articles inserm-00484533v1
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Serotonin 5-HT(2B) receptor blockade prevents reactive oxygen species-induced cardiac hypertrophy in mice.

Laurent Monassier , Marc-André Laplante , Fabrice Jaffré , Pascal Bousquet , Luc Maroteaux
Hypertension, 2008, 52 (2), pp.301-7. ⟨10.1161/HYPERTENSIONAHA.107.105551⟩
Journal articles inserm-00484531v1
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The serotonin 5-HT2B receptor controls bone mass via osteoblast recruitment and proliferation.

Corinne Collet , Corinne Schiltz , Valérie Geoffroy , Luc Maroteaux , Jean-Marie Launay
FASEB Journal, 2008, 22 (2), pp.418-27. ⟨10.1096/fj.07-9209com⟩
Journal articles inserm-00996758v1
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Gain of affinity point mutation in the serotonin receptor gene 5-HT2Dro accelerates germband extension movements during Drosophila gastrulation.

B Schaerlinger , J M Launay , J L Vonesch , Luc Maroteaux
Developmental Dynamics, 2007, 236 (4), pp.991-999. ⟨10.1002/dvdy.21110⟩
Journal articles hal-01274920v1
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Modified Receptor Internalization upon Co-expression of 5-HT1B Receptor and 5-HT2B Receptors.

Agnès Janoshazi , Maud Deraet , Jacques Callebert , Vincent Setola , Silke Guenther
Molecular Pharmacology, 2007, 71 (6), pp.1463-74. ⟨10.1124/mol.106.032656⟩
Journal articles hal-00135110v1
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Endogenous 5-HT2B receptor activation regulates neonatal respiratory activity in vitro

Silke Günther , Luc Maroteaux , Stephan W. Schwarzacher
Journal of Neurobiology, 2006, 66 (9), pp.949-961. ⟨10.1002/neu.20253⟩
Journal articles hal-01274950v1
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Evidence for a control of plasma serotonin levels by 5-hydroxytryptamine(2B) receptors in mice.

J Callebert , J M Esteve , P Hervé , K Peoc'H , C Tournois
Journal of Pharmacology and Experimental Therapeutics, 2006, 317 (2), pp.724-731. ⟨10.1124/jpet.105.098269⟩
Journal articles hal-01274937v1
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Functions of serotonin in hypoxic pulmonary vascular remodeling.

Juan M Esteve , Jean-Marie Launay , Odile Kellermann , Luc Maroteaux
Cell Biochemistry and Biophysics, 2006, 47 (1), pp.33-44. ⟨10.1385/CBB:47:1:33⟩
Journal articles hal-01274919v1
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The Natural Mutation Encoding a C Terminus-Truncated 5-Hydroxytryptamine2B Receptor Is a Gain of Proliferative Functions

Maud Deraet , Philippe Manivet , Agnes Janoshazi , Jacques Callebert , Silke Guenther
Molecular Pharmacology, 2005, 67 (4), pp.983 - 991. ⟨10.1124/mol.104.008268⟩
Journal articles hal-01596608v1
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Involvement of the serotonin 5-HT2B receptor in cardiac hypertrophy linked to sympathetic stimulation: control of interleukin-6, interleukin-1beta, and tumor necrosis factor-alpha cytokine production by ventricular fibroblasts.

Fabrice Jaffré , Jacques Callebert , Alexandre Sarre , Nelly Etienne , Canan G Nebigil
Circulation, 2004, 110 (8), pp.969-974. ⟨10.1161/01.CIR.0000139856.20505.57⟩
Journal articles hal-01274954v1
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Le récepteur 5-HT2B: une cible privilégiée de la sérotonine au niveau cardio-pulmonaire

Nelly Etienne , Bérénice Schaerlinger , Fabrice Jaffré , Luc Maroteaux
Journal de la Société de Biologie, 2004, 198 (1), pp.22-9
Journal articles hal-01274957v1

The developmental role of serotonin: news from mouse molecular genetics.

Patricia Gaspar , Olivier Cases , Luc Maroteaux
Nature Reviews Neuroscience, 2003, 4 (12), pp.1002-12. ⟨10.1038/nrn1256⟩
Journal articles hal-01274960v1
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Serotonin is a novel survival factor of cardiomyocytes: mitochondria as a target of 5-HT 2B receptor signaling

Canan G Nebigil , Nelly Etienne , Nadia Messaddeq , Luc Maroteaux
FASEB Journal, 2003, 17 (10), pp.1373-1375. ⟨10.1096/fj.02-1122fje⟩
Journal articles hal-01985091v1
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Function of the serotonin 5-hydroxytryptamine 2B receptor in pulmonary hypertension

L Launay , P. Herve , K. Peoc'H , C. Tournois , C Callebert
Nature Medicine, 2002, 8 (10), pp.1129-1135. ⟨10.1038/nm764⟩
Journal articles hal-01985063v1
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Ablation of serotonin 5-HT 2B receptors in mice leads to abnormal cardiac structure and function

Canan G Nebigil , Pierre Hickel , Nadia Messaddeq , Jean-Luc Vonesch , Marie P Douchet
Circulation, 2001, 103 (24), pp.2973-2979. ⟨10.1161/01.cir.103.24.2973⟩
Journal articles hal-03721232v1
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C.G. Nebigil , N. Etienne , B. Schaerlinger , P. Hickel , J.‐m. Launay
International Journal of Developmental Neuroscience, 2001, 19 (4), pp.365-372. ⟨10.1016/s0736-5748(01)00022-3⟩
Journal articles hal-03721220v1
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Functional consequence of serotonin/5-HT2B receptor signaling in heart: A role of mitochondria for transition between hypertrophy and heart failure?

Canan G Nebigil , Luc Maroteaux
Trends in Cardiovascular Medicine, 2001, 11 (8), pp.329-335. ⟨10.1016/s1050-1738(01)00135-9⟩
Journal articles hal-03721187v1
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5-Hydroxytryptamine 2B receptor regulates cell-cycle progression: Cross-talk with tyrosine kinase pathways

Canan G Nebigil , J.-M. Launay , Pierre Hickel , C. Tournois , Luc Maroteaux
Proceedings of the National Academy of Sciences of the United States of America, 2000, 97 (6), pp.2591-2596. ⟨10.1073/pnas.050282397⟩
Journal articles hal-02926507v1
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Serotonin 2B receptor is required for heart development

Canan G Nebigil , D.-S. Choi , André Dierich , Pierre Hickel , Marianne Le Meur
Proceedings of the National Academy of Sciences of the United States of America, 2000, 97 (17), pp.9508-9513. ⟨10.1073/pnas.97.17.9508⟩
Journal articles hal-02926424v1

Mouse 5-HT2B receptor-mediated serotonin trophic functions.

D S Choi , Odile Kellermann , S Richard , J F Colas , Francisco Bolaños-Jiménez
Annals of the New York Academy of Sciences, 1998, 861, pp.67-73. ⟨10.1111/j.1749-6632.1998.tb10174.x⟩
Journal articles hal-02693974v1

Preferential expression of 5-HT1D over 5-HT1B receptors during murine embryonic development.

Francisco Bolaños-Jiménez , D S Choi , L Maroteaux
Annals of the New York Academy of Sciences, 1998, 861, pp.238-239. ⟨10.1111/j.1749-6632.1998.tb10198.x⟩
Journal articles hal-02690436v1

Preferential expression of 5-HT1D over 5-HT1B receptors during early embryogenesis.

Francisco Bolaños-Jiménez , D S Choi , L Maroteaux
NeuroReport, 1997, 8 (17), pp.3655-3660. ⟨10.1097/00001756-199712010-00001⟩
Journal articles hal-02696479v1
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5-HT2B receptor-mediated serotonin morphogenetic functions in mouse cranial neural crest and myocardiac cells.

Doo-Sup Choi , Simon J Ward , Nadia Messaddeq , Jean-Marie Launay , Luc Maroteaux
Development (Cambridge, England), 1997, 124 (9), pp.1745-55
Journal articles hal-02926362v1
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Evolutionary conservation of the 5-HT 2B receptors

Jean-François Colas , D.-S. Choi , Jean-Marie Launay , Luc Maroteaux
Annals of the New York Academy of Sciences, 1997, 812 (1 Receptor Clas), pp.149-153. ⟨10.1111/j.1749-6632.1997.tb48157.x⟩
Journal articles hal-03721324v1
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The 5-HT2B Receptor Gene Maps to 2q36.3–2q37.1

Maryvonne Le Coniat , Doo-Sup Choi , Luc Maroteaux , Jean-Marie Launay , Roland Berger
Genomics, 1996, 32 (1), pp.172-173. ⟨10.1006/geno.1996.0101⟩
Journal articles hal-03721346v1

Behavioral outcomes of microglial dysfunction across the life span

Luc Maroteaux , Giulia Albertini , Ivana D’andrea , Anne Roumier
XV European Meeting on Glial Cells in Health and Disease,, Jul 2021, Marseille (On line), France
Conference papers hal-03960442v1
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Invalidation of 5-HT2B receptors on microglia impairs microglia processes motility

Fanny Etienne , Giulia Albertini , Ivana D’andrea , Imane Moutkine , Nicolas Gervasi
14th European Meeting on Glial Cells in Health and Disease (GLIA), Jul 2019, Porto,, Portugal
Conference papers hal-03960409v1
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Serotonin 2B receptor potentiates erythropoietin-induced mobilization of endothelial progenitor cells: contribution to hypoxic pulmonary arterial hypertension?

Estelle Ayme-Dietrich , Jerome Becker , Ghina Bou About , Luc Maroteaux , Lahcen El Fertak
Annual Meeting of French Society of Pharmacology and Therapeutics, and INSERM Clinical Research Centers (CIC), Jun 2018, Toulouse, France
Conference papers hal-03960373v1

Lack of serotonin 2B receptor gene drives depressive-like phenotype induced by chronic stress: a potential role for microglia?

I. D’andrea , Luc Maroteaux , A. Roumier
30th Congress of the European-College-of-Neuropsychopharmacology (ECNP), Sep 2017, Paris, France. pp.S676, ⟨10.1016/S0924-977X(17)31259-2⟩
Conference papers hal-03959743v1

Serotonergic 5-HT2B receptors in mitral valvulopathy: bone marrow mobilization of endothelial progenitors

Luc Maroteaux , Estelle Ayme-Dietrich , Roland Lawson , Laurent Monassier
Joint Meeting of the Federation of European Physiological Societies and the Austrian Physiological Society with Participation of the Czech, French, Italian, Slovak, Slovenian, Swiss and Turkish Physiological Societies,, Sep 2017, Vienna, Austria
Conference papers hal-03960331v1
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Gene Structure, Expression, and 5-HT2B Receptor Signaling

Luc Maroteaux
5-HT2B Receptors. The Receptors, vol 35., pp.1-32, 2021, ⟨10.1007/978-3-030-55920-5_1⟩
Book sections hal-03217218v1
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Serotonin and 5-HT2B receptors in microglia control of behavior

Ivana d'Andrea , Catherine Béchade , Luc Maroteaux
HANDBOOK OF THE BEHAVIORAL NEUROBIOLOGY OF SEROTONIN, pp.589-599, 2020, ⟨10.1016/B978-0-444-64125-0.00034-7⟩
Book sections hal-02544886v1
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Serotonin and Cardiovascular Diseases

Laurent Monassier , Luc Maroteaux
Paul M Pilowsky. Serotonin. The mediator that spans evolution, Elsevier, pp.203-238, 2019, 978-0-12-800050-2. ⟨10.1016/B978-0-12-800050-2.00012-7⟩
Book sections hal-03217295v1
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Serotonin and the Immune System

Anne Roumier , Catherine Béchade , Luc Maroteaux
Paul M Pilowsky. Serotonin. The Mediator That Spans Evolution, Elsevier, pp.181-196, 2019, 978-0-12-800050-2. ⟨10.1016/B978-0-12-800050-2.00010-3⟩
Book sections hal-03217301v1