LK

Lucie KARAYAN-TAPON

56
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Publications

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PFMG2025–integrating genomic medicine into the national healthcare system in France

Caroline Abadie , Aldja Abderrahmane , Ouarda Abdous , Carine Abel , Oanez Ackermann et al.
The Lancet Regional Health - Europe, 2025, 50, ⟨10.1016/j.lanepe.2024.101183⟩
Article dans une revue hal-04988732 v1

An Innovative and Accurate Next-Generation Sequencing–Based Microsatellite Instability Detection Method for Colorectal and Endometrial Tumors

Camille Evrard , Ulrich Cortes , Birama Ndiaye , Justine Bonnemort , Marine Martel et al.
Laboratory Investigation, 2024, 104 (2), pp.100297. ⟨10.1016/j.labinv.2023.100297⟩
Article dans une revue hal-04648827 v1
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VC-resist glioblastoma cell state: vessel co-option as a key driver of chemoradiation resistance

Cathy Pichol-Thievend , Oceane Anezo , Aafrin Pettiwala , Guillaume Bourmeau , Remi Montagne et al.
Nature Communications, 2024, 15 (1), pp.3602. ⟨10.1038/s41467-024-47985-z⟩
Article dans une revue hal-04648492 v1

The Vitamin K-Dependent Anticoagulant Factor, Protein S, Regulates Vascular Permeability

Aurélie Joussaume , Chryso Kanthou , Olivier Pardo , Lucie Karayan-Tapon , Omar Benzakour et al.
Current Issues in Molecular Biology, 2024, 46 (4), pp.3278-3293. ⟨10.3390/cimb46040205⟩
Article dans une revue hal-05038293 v1
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Yes-Associated Protein Nuclear Translocation Is Regulated by Epidermal Growth Factor Receptor Activation Through Phosphatase and Tensin Homolog/AKT Axis in Glioblastomas

Konstantin Masliantsev , Margaux Mordrel , Tania Banor , Amandine Desette , Julie Godet et al.
Laboratory Investigation, 2023, 103 (5), pp.100053. ⟨10.1016/j.labinv.2022.100053⟩
Article dans une revue hal-04098700 v1

Immunohistochemistry, Molecular Biology, and Clinical Scoring for the Detection of Muir-Torre Syndrome in Cutaneous Sebaceous Tumors: Which Strategy?

Hélinie Sinson , Lucie Karayan-tapon , Julie Godet , Pierre Rivet , Camille Alleyrat et al.
Dermatology, 2023, 239 (6), pp.889-897. ⟨10.1159/000534126⟩
Article dans une revue hal-04487948 v1
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Deciphering Brain Metastasis Stem Cell Properties From Colorectal Cancer Highlights Specific Stemness Signature and Shared Molecular Features

Amandine Desette , Pierre-Olivier Guichet , Sheik Emambux , Konstantin Masliantsev , Ulrich Cortes et al.
Cellular and Molecular Gastroenterology and Hepatology, 2023, 16 (5), pp.757-782. ⟨10.1016/j.jcmgh.2023.07.008⟩
Article dans une revue hal-04302791 v1
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Circulating tumor DNA in unresectable pancreatic cancer is a strong predictor of first-line treatment efficacy: The KRASCIPANC prospective study

Camille Evrard , Pierre Ingrand , Tristan Rochelle , Marine Martel , Gaëlle Tachon et al.
Digestive and Liver Disease, 2023, 55 (11), pp.1562-1572. ⟨10.1016/j.dld.2023.03.011⟩
Article dans une revue hal-04648773 v1

The M2 macrophages infiltration of sebaceous tumors is linked to the aggressiveness of tumors but not to the mismatch repair pathway

Eric Frouin , Camille Alleyrat , Julie Godet , Lucie Karayan-Tapon , Hélinie Sinson et al.
Journal of Cancer Research and Clinical Oncology, 2023, 149 (9), pp.6445-6454. ⟨10.1007/s00432-023-04629-x⟩
Article dans une revue hal-04185363 v1
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HSP110 as a Diagnostic but Not a Prognostic Biomarker in Colorectal Cancer With Microsatellite Instability

Gaelle Tachon , Arnaud Chong-Si-Tsaon , Thierry Lecomte , Audelaure Junca , Éric Frouin et al.
Frontiers in Genetics, 2022, 12, pp.769281. ⟨10.3389/fgene.2021.769281⟩
Article dans une revue hal-04343223 v1
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The Long Non-Coding RNA HOXA-AS2 Promotes Proliferation of Glioma Stem Cells and Modulates Their Inflammation Pathway Mainly through Post-Transcriptional Regulation

Elisa Le Boiteux , Pierre-Olivier Guichet , Konstantin Masliantsev , Bertille Montibus , Catherine Vaurs-Barriere et al.
International Journal of Molecular Sciences, 2022, 23 (9), pp.4743. ⟨10.3390/ijms23094743⟩
Article dans une revue hal-03668886 v1
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L1 chimeric transcripts are expressed in healthy brain and their deregulation in glioma follows that of their host locus

Marie-Elisa Pinson , Franck Court , Aymeric Masson , Yoan Renaud , Allison Fantini et al.
Human Molecular Genetics, 2022, 31 (15), pp.2606-2622. ⟨10.1093/hmg/ddac056⟩
Article dans une revue hal-03631345 v1
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MEOX2 Transcription Factor Is Involved in Survival and Adhesion of Glioma Stem-like Cells

Gaëlle Tachon , Konstantin Masliantsev , Pierre Rivet , Amandine Desette , Serge Milin et al.
Cancers, 2021, 13 (23), pp.5943. ⟨10.3390/cancers13235943⟩
Article dans une revue hal-04098666 v1

Le Conseil national des universités en cancérologie-radiothérapie : actualisation des critères de sélection présentés aux lecteurs du Bulletin du Cancer

Gilles Calais , Jean-Marc Classe , Michel Ducreux , Christophe Hennequin , Florence Joly et al.
Bulletin du Cancer, 2021, 108 (10), pp.895 - 899. ⟨10.1016/j.bulcan.2021.08.005⟩
Article dans une revue hal-03603935 v1
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Standardisation of pathogenicity classification for somatic alterations in solid tumours and haematologic malignancies

Florence Koeppel , Etienne Muller , Alexandre Harlé , Celine Guien , Pierre Sujobert et al.
European Journal of Cancer, 2021, 159, pp.1-15. ⟨10.1016/j.ejca.2021.08.047⟩
Article dans une revue hal-03408473 v1
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Discordance between immunochemistry of mismatch repair proteins and molecular testing of microsatellite instability in colorectal cancer

A. Guyot d'Asnières de Salins , G. Tachon , R. Cohen , L. Karayan-Tapon , A. Junca et al.
ESMO Open, 2021, 6 (3), pp.100120. ⟨10.1016/j.esmoop.2021.100120⟩
Article dans une revue hal-03215245 v1
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Phase 1 trial of ralimetinib (LY2228820) with radiotherapy plus concomitant temozolomide in the treatment of newly diagnosed glioblastoma

J. Biau , E. Thivat , E. Chautard , D. Stefan , Mathieu Boone et al.
Radiotherapy & Oncology, 2021, 154 (227-234), ⟨10.1016/j.radonc.2020.09.036⟩
Article dans une revue hal-02954534 v1

New Artificial Intelligence Score and Immune Infiltrates as Prognostic Factors in Colorectal Cancer With Brain Metastases

Violaine Randrian , Amandine Desette , Sheik Emambux , Valentin Derangere , Pauline Roussille et al.
Frontiers in Immunology, 2021, 12, ⟨10.3389/fimmu.2021.750407⟩
Article dans une revue hal-04098709 v1
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Widespread overexpression from the four DNA hypermethylated HOX clusters in aggressive (IDHwt) glioma is associated with H3K27me3 depletion and alternative promoter usage

Elisa Le Boiteux , Franck Court , Pierre‐Olivier Guichet , Catherine Vaurs-Barrière , Isabelle Vaillant et al.
Molecular Oncology, 2021, ⟨10.1002/1878-0261.12944⟩
Article dans une revue hal-03172071 v1

Hippo Signaling Pathway in Gliomas

Konstantin Masliantsev , Lucie Karayan-Tapon , Pierre-Olivier Guichet
Cells, 2021, 10 (1), pp.184. ⟨10.3390/cells10010184⟩
Article dans une revue hal-04099076 v1
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New Insights into Expression of Hormonal Receptors by Meningiomas

Sylvain Portet , Tania Banor , Jonathan Bousquet , Adrien Simonneau , Marie Flores et al.
World Neurosurgery, 2020, 140, pp.e87 - e96. ⟨10.1016/j.wneu.2020.04.168⟩
Article dans une revue hal-03491283 v1

A Comparative Study of Anoikis Resistance Assays for Tumor Cells

Aurélie Joussaume , Lucie Karayan-tapon , Omar Benzakour , Fatima Dkhissi
Biomedical Journal of Scientific & Technical Research, 2020, 29 (2), ⟨10.26717/BJSTR.2020.29.004767⟩
Article dans une revue hal-05038514 v1
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Transcriptional alterations in glioma result primarily from DNA methylation independent mechanisms

Franck Court , Elisa Le Boiteux , Anne Fogli , Mélanie Müller-Barthélémy , Catherine Vaurs-Barrière et al.
Genome Research, 2019, 29 (10), pp.1605-1621. ⟨10.1101/gr.249219.119⟩
Article dans une revue hal-02304180 v2

Prognostic significance of MEOX2 in gliomas

Gaelle Tachon , Konstantin Masliantsev , Pierre Rivet , Christos Petropoulos , Julie Godet et al.
Modern Pathology, 2019, 32 (6), pp.774-786. ⟨10.1038/s41379-018-0192-6⟩
Article dans une revue hal-04098976 v1

Cell Cycle Changes after Glioblastoma Stem Cell Irradiation: The Major Role of RAD51

Gaelle Tachon , Ulrich Cortes , Pierre-Olivier Guichet , Pierre Rivet , Anais Balbous et al.
International Journal of Molecular Sciences, 2018, 19 (10), pp.3018. ⟨10.3390/ijms19103018⟩
Article dans une revue hal-02538718 v1

Impact of STAT3 phosphorylation in glioblastoma stem cells radiosensitization and patient outcome

Konstantin Masliantsev , Baptiste Pinel , Anais Balbous , Pierre-Olivier Guichet , Gaelle Tachon et al.
Oncotarget, 2018, 9 (3), pp.3968-3979. ⟨10.18632/oncotarget.23374⟩
Article dans une revue hal-02538688 v1

Functional invadopodia formed in glioblastoma stem cells are important regulators of tumor angiogenesis

Christos Petropoulos , Pierre-Olivier Guichet , Konstantin Masliantsev , Michel Wager , Lucie Karayan-Tapon
Oncotarget, 2018, 9 (29), pp.20640-20657. ⟨10.18632/oncotarget.25045⟩
Article dans une revue hal-04099011 v1

Fatal correlation between YAP1 expression and glioma aggressiveness: clinical and molecular evidence

Pierre-Olivier Guichet , Konstantin Masliantsev , Gaëlle Tachon , Christos Petropoulos , Julie Godet et al.
The Journal of pathology and bacteriology, 2018, 246 (2), pp.205-216. ⟨10.1002/path.5133⟩
Article dans une revue hal-04098987 v1

Crizotinib targets in glioblastoma stem cells

Audelaure Junca , Claire Villalva , Gaelle Tachon , Pierre Rivet , Ulrich Cortes et al.
Cancer Medicine, 2017, 6 (11), pp.2625-2634. ⟨10.1002/cam4.1167⟩
Article dans une revue hal-02538685 v1
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Clinical validation of the CE-IVD marked Therascreen MGMT kit in a cohort of glioblastoma patients

Véronique Quillien , Audrey Lavenu , François Ducray , David Meyronet , Olivier Chinot et al.
Cancer Biomarkers, 2017, 20 (4), pp.435-441. ⟨10.3233/CBM-170191⟩
Article dans une revue hal-01680957 v1

A radiosensitizing effect of RAD51 inhibition in glioblastoma stem-like cells

Anais Balbous , Ulrich Cortes , Karline Guilloteau , Pierre Rivet , Baptiste Pinel et al.
BMC Cancer, 2016, 16 (1), ⟨10.1186/s12885-016-2647-9⟩
Article dans une revue hal-02538679 v1

The tumoral A genotype of the MGMT rs34180180 single-nucleotide polymorphism in aggressive gliomas is associated with shorter patients’ survival

Anne Fogli , Emmanuel Chautard , Catherine Vaurs-Barrière , Bruno Pereira , Mélanie Müller-Barthélémy et al.
Carcinogenesis, 2016, 37 (2), pp.169 - 176. ⟨10.1093/carcin/bgv251⟩
Article dans une revue hal-01629349 v1
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Validation of the high-performance of pyrosequencing for clinical MGMT testing on a cohort of glioblastoma patients from a prospective dedicated multicentric trial

Véronique Quillien , Audrey Lavenu , François Ducray , Marie-Odile Joly , Olivier Chinot et al.
Oncotarget, 2016, 7 (38), pp.61916-61929. ⟨10.18632/oncotarget.11322⟩
Article dans une revue hal-01358205 v1
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IL22/IL-22R Pathway Induces Cell Survival in Human Glioblastoma Cells

Hussein Akil , Amazigh Abbaci , Barbara Bessette , Lea Costes , Linda Domballe et al.
PLoS ONE, 2015, 10 (3), pp.e0119872. ⟨10.1371/journal.pone.0119872⟩
Article dans une revue hal-01704496 v1
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Outcome-based determination of optimal pyrosequencing assay for MGMT methylation detection in glioblastoma patients.

Véronique Quillien , Audrey Lavenu , Marc Sanson , Michèle Legrain , Pierre Dubus et al.
Journal of Neuro-Oncology, 2014, 116 (3), pp.487-496. ⟨10.1007/s11060-013-1332-y⟩
Article dans une revue hal-00935512 v1

A mesenchymal glioma stem cell profile is related to clinical outcome

A Balbous , U Cortes , K Guilloteau , C Villalva , S. Flamant et al.
Oncogenesis, 2014, 3 (3), pp.e91-e91. ⟨10.1038/oncsis.2014.5⟩
Article dans une revue hal-02530857 v1
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DGKI Methylation Status Modulates the Prognostic Value of MGMT in Glioblastoma Patients Treated with Combined Radio-Chemotherapy with Temozolomide

Amandine Etcheverry , Marc Aubry , Ahmed Idbaih , Elodie Vauleon , Yannick Marie et al.
PLoS ONE, 2014, 9 (9), pp.e104455. ⟨10.1371/journal.pone.0104455⟩
Article dans une revue hal-01358132 v1

Selective Release of a Cyclopamine Glucuronide Prodrug toward Stem-like Cancer Cell Inhibition in Glioblastoma

Anais Balbous , Brigitte Renoux , Ulrich Cortes , Serge Milin , Karline Guilloteau et al.
Molecular Cancer Therapeutics, 2014, 13 (9), pp.2159-2169. ⟨10.1158/1535-7163.MCT-13-1038⟩
Article dans une revue hal-01313891 v1

Comparative assessment of 5 methods (methylation-specific polymerase chain reaction, methylight, pyrosequencing, methylation-sensitive high-resolution melting, and immunohistochemistry) to analyze O6-methylguanine-DNA-methyltranferase in a series of 100 glioblastoma patients.

Véronique Quillien , Audrey Lavenu , Lucie Karayan-Tapon , Catherine Carpentier , Marianne Labussière et al.
Cancer, 2012, 118 (17), pp.4201-4211. ⟨10.1002/cncr.27392⟩
Article dans une revue inserm-00667080 v1

Altered expression of the gap junction protein connexin43 is associated with papillary thyroid carcinomas when compared with other noncancer pathologies of the thyroid.

Claudia Dominguez , Lucie Karayan-Tapon , Thibault Desurmont , Hélène Gibelin , Sophie Crespin et al.
Thyroid, 2011, 21 (10), pp.1057-66. ⟨10.1089/thy.2011.0041⟩
Article dans une revue hal-00993028 v1

Glycosylation-related gene expression is linked to differentiation status in glioblastomas undifferentiated cells

Mathilde Cheray , Daniel Petit , Lionel Forestier , Lucie Karayan-Tapon , Abderrahman A. Maftah et al.
Cancer Letters, 2011, 312 (1), pp.24-32. ⟨10.1016/j.canlet.2011.07.027⟩
Article dans une revue istex hal-02888191 v1

Glycosylation-related gene expression is linked to differentiation status in glioblastomas undifferentiated cells.

Mathilde Cheray , Daniel Petit , Lionel Forestier , Lucie Karayan-Tapon , Abderrahman Maftah et al.
Cancer Letters, 2011, 312 (1), pp.24-32. ⟨10.1016/j.canlet.2011.07.027⟩
Article dans une revue istex hal-00873130 v1

STAT3 is essential for the maintenance of neurosphere-initiating tumor cells in patients with glioblastomas: A potential for targeted therapy?

Claire Villalva , Severine Martin-Lannerée , Ulrich Cortes , Fatima Dkhissi , Michel Wager et al.
International Journal of Cancer, 2011, 128 (4), pp.826-838. ⟨10.1002/ijc.25416⟩
Article dans une revue hal-04033986 v1

Prognostic value of O6-methylguanine-DNA methyltransferase status in glioblastoma patients, assessed by five different methods.

Lucie Karayan-Tapon , Véronique Quillien , Joëlle Guilhot , Michel Wager , Gaëlle Fromont et al.
Journal of Neuro-Oncology, 2010, 97 (3), pp.311-22. ⟨10.1007/s11060-009-0031-1⟩
Article dans une revue istex inserm-00435222 v1
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An ANOCEF genomic and transcriptomic microarray study of the response to radiotherapy or to alkylating first-line chemotherapy in glioblastoma patients.

François Ducray , Aurélien de Reyniès , Olivier Chinot , Ahmed Idbaih , Dominique Figarella-Branger et al.
Molecular Cancer, 2010, 9 (1), pp.234. ⟨10.1186/1476-4598-9-234⟩
Article dans une revue inserm-00668209 v1
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Increasing the Number of Thyroid Lesions Classes in Microarray Analysis Improves the Relevance of Diagnostic Markers

Jean-Fred Fontaine , Delphine Mirebeau-Prunier , Mahatsangy Raharijaona , Brigitte Franc , Stéphane Triau et al.
PLoS ONE, 2009, 4 (10), pp.e7632. ⟨10.1371/journal.pone.0007632⟩
Article dans une revue hal-03275613 v1
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Prognostic molecular markers with no impact on decision-making: the paradox of gliomas based on a prospective study

Michel Wager , Philippe Menei , Joëlle Guilhot , Pierre Levillain , Sophie Michalak et al.
British Journal of Cancer, 2008, 98 (11), pp.1830-8. ⟨10.1038/sj.bjc.6604378⟩
Article dans une revue hal-03171814 v1

Semaphorin, neuropilin and VEGF expression in glial tumours: SEMA3G, a prognostic marker?

Lucie Karayan-Tapon , Michel Wager , Joëlle Guilhot , Pierre Levillain , C. Marquant et al.
British Journal of Cancer, 2008, 99 (7), pp.1153-1160. ⟨10.1038/sj.bjc.6604641⟩
Article dans une revue hal-00458867 v1

Recent acquisitions on functional properties of the p14/p19ARF tumor suppressor protein and its importance in oncohaematology

Lucie Karayan-tapon , Paule Séité , Olivier Ayrault , Christian-Jacques Larsen
Hématologie, 2002, 8 (6), pp.427-438
Article dans une revue hal-04654438 v1
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Human ARF binds E2F1 and inhibits its transcriptional activity

Béatrice Eymin , Lucie Karayan , Paule Séité , Christian Brambilla , Elisabeth Brambilla et al.
Oncogene, 2001, 20 (9), pp.1033-41. ⟨10.1038/sj.onc.1204220⟩
Article dans une revue inserm-02345407 v1

Human ARF protein interacts with Topoisomerase I and stimulates its activity

Lucie Karayan , Jean-François Riou , Paule Séité , Julien Migeon , Anne Cantereau et al.
Oncogene, 2001, 20 (7), pp.836-848. ⟨10.1038/sj.onc.1204170⟩
Article dans une revue hal-04654393 v1

Radiosensitization of Glioblastoma Stem Cells by inhibition of STAT3

Konstantin Masliantsev , Baptiste Pinel , Anais Balbous , Pierre-Olivier Guichet , Serge Milin et al.
Canceropole Grand Sud-Ouest, Nov 2016, Montpellier, France
Poster de conférence hal-02538770 v1

Analyse protéomique des glioblastones: Quel est le meilleur contrôle?

Jean-Michel Lemée , Emmanuelle Com , Anne Clavreul , Tony Avril , V Quillien et al.
7èmes journées du Cancérôpole Grand Ouest, 2013, Les Sables d'Olonne, France. 2013
Poster de conférence hal-03180645 v1

Etude de l’effet du premier vecteur glucuronylé de la cyclopamine sur les cellules initiatrices de glioblastomes

Anais Balbous , Brigitte Renoux , Ulrich Cortes , Serge Milin , Karline Guilloteau et al.
6ème journée de la Recherche Tours-Poitiers, Nov 2013, Poitiers, France
Poster de conférence hal-02538758 v1

Etude de l’effet du premier vecteur glucuronylé de la cyclopamine sur les cellules initiatrices de glioblastomes

Anais Balbous , Thibaut Legigan , Brigitte Renoux , Ulrich Cortes , Pierre Rivet et al.
6ème colloque du Cancéropole PACA- Glioblastomes, Feb 2012, Marseille, France
Poster de conférence hal-02538740 v1

Etude de l’effet du premier vecteur glucuronylé de la cyclopamine sur les cellules initiatrices de glioblastomes

Anais Balbous , Thibaut Legigan , Brigitte Renoux , Ulrich Cortes , Pierre Rivet et al.
6ème journée du Cancéropole Grand-Ouest Tours-Poitiers, Angers, Jun 2012, Angers, France
Poster de conférence hal-02538745 v1