Access content directly

marc pocard



Prof. Marc Pocard did his residency in the Paris Hospitals and during the same time studied colorectal cancer biology at the Curie Institut. He worked during 5 years as a surgeon at the Gustave Roussy Institute in Paris during which he also had the opportunity to work on peritoneal metastatic diseases. In 2006 he was nominated Professor in digestive surgery at the Paris Diderot University. He developed a peritoneal metastasis treatment program, in association with the French RENAPE network for rare peritoneal cancers. In 2009 he created a research Unit at the INSERM on Angiogenesis and again in 2019 a research Unit specifically devoted to basic and translational research on peritoneal metastasis. He practices HIPEC and PIPAC in a routine manner and is involved in clinical trials related to peritoneal metastasis. In 2018 he cofounded the International Society for the Study of Pleura and Peritoneum, named ISSPP and was elected as the first president of the ISSPP society. Subjects of interest on research are: \- Evaluation of new intraperitoneal drugs delivery using nanotechnology, gel as a drug carrier solution or PIPAC and associations for peritoneal metastasis \- Evaluation of new treatments in Pseudomyxoma animal model \- Comprehensive study on gastric adenocarcinoma with single ring cells \- Conception of global evaluation procedure for loco regional treatment in Cancer, including personal and societal aspect


PIPAC nebulizer : How to test the new devices in the market, expert recommendations

M Pocard , J B Y So , C Huchon , M Robella , Pascale Chavatte-Palmer
Journal of Visceral Surgery, 2023, 160 (1), pp.52-54. ⟨10.1016/j.jviscsurg.2022.10.001⟩
Journal articles hal-03826077v1
Image document

Nebulization is less effective than aerosolization, in PIPAC live animal drug delivery testing

Marc Pocard , Myriam Mimouni , Christophe Richard , Pierre Adenot , Cyrille Huchon
Surgery Open Digestive Advance, 2023, 9, pp.100078. ⟨10.1016/j.soda.2022.100078⟩
Journal articles hal-03984286v1
Image document

Panel gene profiling of small bowel adenocarcinoma, results from the NADEGE prospective cohort

Thomas Aparicio , Magali Svrcek , Julie Henriques , Pauline Afchain , Astrid Lièvre
International Journal of Cancer, 2021, 148 (7), pp.1731-1742. ⟨10.1002/ijc.33392⟩
Journal articles hal-03038573v1
Image document

Personal experience and/or shared experience in surgery?

Marc Pocard
Journal of Visceral Surgery, 2021, 158 (4), pp.287-288. ⟨10.1016/j.jviscsurg.2021.07.005⟩
Journal articles hal-03477809v1
Image document

Detection of Persistent Organic Pollutants in Omental Adipose Tissue from Patients with Diffuse-Gastric Cancer: A Pilot Study

Martine Perrot-Applanat , Cynthia Pimpie , Germán Cano-Sancho , Jean-Philippe Antignac , Marc Pocard
Cancers, 2021, 13 (19), pp.4874. ⟨10.3390/cancers13194874⟩
Journal articles hal-04000634v1

Half of Postoperative Deaths After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy Could be Preventable A French Root Cause Analysis on 5562 Patients

Constance Houlze-Laroye , Olivier Glehen , Olivia Sgarbura , Etienne Gayat , Isabelle Sourrouille
Annals of Surgery, 2021, 274 (5), pp.797-804. ⟨10.1097/SLA.0000000000005101⟩
Journal articles hal-03566161v1

Ovarian and peritoneal psammocarcinoma: Results of a multicenter study on 25 patients

Jean-Baptiste Delhorme , Jordan Ohayon , Sébastien Gouy , Catherine Genestie , Léopold Gaichies
EJSO - European Journal of Surgical Oncology, 2020, 46 (5), pp.862-867. ⟨10.1016/j.ejso.2019.12.005⟩
Journal articles hal-02533020v1

Small bowel adenocarcinoma: Results from a nationwide prospective ARCAD‐NADEGE cohort study of 347 patients

Thomas T. Aparicio , Julie Henriques , Sylvain Manfredi , David Tougeron , Olivier Bouche
International Journal of Cancer, 2020, ⟨10.1002/ijc.32860⟩
Journal articles hal-02532893v1

Differentiation of cancer cells upregulates HLA‑G and PD‑L1

Matti Ullah , Sarah Meziani , Shahid Shah , Rachid Kaci , Cynthia Pimpie
Oncology Reports, 2020, ⟨10.3892/or.2020.7572⟩
Journal articles hal-02551167v1
Image document

Multi-nanolayer drug delivery using radiofrequency plasma technology

Iman Al Dybiat , Alibi Baitukha , Cynthia Pimpie , Rachid Kaci , Marc Pocard
BMC Cancer, 2020, 20 (565), pp.11P. ⟨10.1186/s12885-020-06989-w⟩
Journal articles hal-02879735v1
Image document

Strategy for the practice of digestive and oncological surgery during the Covid-19 epidemic.

J.-J Tuech , A. Gangloff , F. Fiore , P. Michel , C. Brigand
Journal of Visceral Surgery, inPress, ⟨10.1016/j.jviscsurg.2020.03.008⟩
Journal articles hal-02552052v1
Image document

Development and internal validation of a diagnostic score for gastric linitis plastica

J. Vivier-Chicoteau , J. Lambert , R. Coriat , P. E Bonnot , D. Goéré
Gastric Cancer, inPress, ⟨10.1007/s10120-020-01051-x⟩
Journal articles hal-02555520v1

Can we cure patients with abdominal Desmoplastic Small Round Cell Tumor? Results of a retrospective multicentric study on 100 patients

C. Honore , J.B. Delhorme , E. Nassif , M. Faron , G. Ferron
Surgical Oncology, 2019, 29, pp.107-112. ⟨10.1016/j.suronc.2019.04.002⟩
Journal articles hal-02528457v1
Image document

Oxaliplatin use in pressurized intraperitoneal aerosol chemotherapy (PIPAC) is safe and effective: A multicenter study

Olivia Sgarbura , Martin Hübner , Mohammad Alyami , Clarisse Eveno , Johan Gagnière
EJSO - European Journal of Surgical Oncology, 2019, 45 (12), pp.2386-2391. ⟨10.1016/j.ejso.2019.05.007⟩
Journal articles hal-02432145v1
Image document

Resection of small bowel adenocarcinoma metastases: Results of the ARCAD-NADEGE cohort study

Pierre Rompteaux , Johan Gagniere , Jean-Marc Gornet , Romain Coriat , Isabelle Baumgaertner
EJSO - European Journal of Surgical Oncology, 2019, 45 (3), pp.331-335. ⟨10.1016/j.ejso.2018.11.012⟩
Journal articles hal-02180462v1
Image document

Adenocarcinoma of the oesophagogastric junction Siewert II: An oesophageal cancer better cured with total gastrectomy

Thibault Voron , Caroline Gronnier , Arnaud Pasquer , Jérémie Thereaux , Johan Gagnière
EJSO - European Journal of Surgical Oncology, 2019, 45 (12), pp.2473-2481. ⟨10.1016/j.ejso.2019.07.022⟩
Journal articles hal-02533008v1
Image document

Optimization of a low pressure plasma process for fabrication of a Drug Delivery System (DDS) for cancer treatment

Alibi Baitukha , Iman Al-Dybiat , Azadeh Valinataj Omran , Jérôme Pulpytel , Marc Pocard
Materials Science and Engineering: C, 2019, 105, pp.110089. ⟨10.1016/j.msec.2019.110089⟩
Journal articles hal-02289769v1

Iterative cytoreductive surgery with or without hyperthermic intraperitoneal chemotherapy for colorectal peritoneal metastases: A multi‐institutional experience

Nayef Alzahrani , Sarah Valle , Oliver Fisher , Paul H. Sugarbaker , Yutaka Yonemura
Journal of Surgical Oncology, 2019, 119 (3), pp.336-346. ⟨10.1002/jso.25277⟩
Journal articles hal-02060121v1

CHIP et cancer de l’ovaire

F. Lécuru , N. Bakrin , J.M. Classe , P.E. Colombo , G. Ferron
Gynécologie Obstétrique Fertilité & Sénologie, 2019, 47 (9), pp.617-618. ⟨10.1016/j.gofs.2019.06.007⟩
Journal articles hal-02343556v1

Low pressure plasma processing of collagen membranes for anti-cancer drug delivery

Alibi Baitukha , Farzaneh Arefi-Khonsari , Jérôme Pulpytel , Iman Al-Dybiat , Azadeh Valinataj-Omran
Journal of Material Sciences & Engineering, 2018, 7 (6), e1000499-(6p.). ⟨10.4172/2169-0022.1000499⟩
Journal articles hal-01989881v1

Cytoreductive Surgery Plus Hyperthermic Intraperitoneal Chemotherapy for Peritoneal Metastases From a Small Bowel Adenocarcinoma: Multi-Institutional Experience

Yang Liu , Yutaka Yonemura , Edward Levine , Olivier Glehen , Diane Goere
Annals of Surgical Oncology, 2018, 25 (5), pp.1184-1192. ⟨10.1245/s10434-018-6369-x⟩
Journal articles hal-02290071v1

Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for pseudomyxoma peritonei of appendicular and extra-appendicular origin

J.-B. Delhorme , F. Severac , G. Averous , O. Glehen , G. Passot
British Journal of Surgery, 2018, 105 (6), pp.668-676. ⟨10.1002/bjs.10716⟩
Journal articles hal-02264128v1

Impact of combination chemotherapy in peritoneal mesothelioma hyperthermic intraperitoneal chemotherapy (HIPEC): The RENAPE study

Brice Malgras , Etienne Gayat , Olivier Aoun , Réa Lo Dico , Clarisse Eveno
Annals of Surgical Oncology, 2018, 25 (11), pp.3271-3279. ⟨10.1245/s10434-018-6631-2⟩
Journal articles hal-02264137v1

Cytoreductive surgery and HIPEC improve survival compared to palliative chemotherapy for biliary carcinoma with peritoneal metastasis: A multi-institutional cohort from PSOGI and BIG RENAPE groups

I. Amblard , F. Mercier , D.L. Bartlett , S.A. Ahrendt , K.W. Lee
EJSO - European Journal of Surgical Oncology, 2018, 44 (9), pp.1378-1383. ⟨10.1016/j.ejso.2018.04.023⟩
Journal articles hal-02281342v1
Image document

CCL2/CCL5 secreted by the stroma induce IL-6/PYK2 dependent chemoresistance in ovarian cancer

Jennifer Pasquier , Marie Gosset , Caroline Geyl , Jessica Hoarau-Véchot , Audrey Chevrot
Revue Européenne des Éléments Finis, 2018, 17 (1), pp.47. ⟨10.1186/s12943-018-0787-z⟩
Journal articles inserm-01716892v1

Small bowel adenocarcinoma: French intergroup clinical practice guidelines for diagnosis, treatments and follow-up (SNFGE, FFCD, GERCOR, UNICANCER, SFCD, SFED, SFRO)

Christophe Locher , Blaise Batumona , Pauline Afchain , Nicolas Carrère , Emmanuelle Samalin
Digestive and Liver Disease, 2018, 50 (1), pp.15 - 19. ⟨10.1016/j.dld.2017.09.123⟩
Journal articles hal-01708040v1
Image document

What Is the most Important for Elite Control: Genetic Background of Patient, Genetic Background of Partner, both or neither? Description of Complete Natural History within a Couple of MSM

M. Bendenoun , A. Samri , V. Avettand-Fènoël , S. Cardinaud , B. Descours
EBioMedicine, 2018, 27, pp.51-60. ⟨10.1016/j.ebiom.2017.12.003⟩
Journal articles hal-01909034v1
Image document

Impact of MLH1 expression on tumor evolution after curative surgical tumor resection in a murine orthotopic xenograft model for human MSI colon cancer

Katy Meunier , Marianne Ferron , Claire Calmel , Jean-François Fléjou , Marc Pocard
Genes, Chromosomes & Cancer, 2017, ⟨10.1002/gcc.22472⟩
Journal articles hal-01548232v1

Immunohistochemical evaluation of two antibodies against PD-L1 and prognostic significance of PD-L1 expression in epithelioid peritoneal malignant mesothelioma: A RENAPE study

S. Valmary-Degano , P. Colpart , L. Villeneuve , F. Monnien , L. M'Hamdi
EJSO - European Journal of Surgical Oncology, 2017, 43 (10), pp.1915-1923. ⟨10.1016/j.ejso.2017.05.009⟩
Journal articles hal-02269932v1

One-month apparent diffusion coefficient correlates with response to radiofrequency ablation of hepatocellular carcinoma.

M Barat , A Fohlen , C Cassinotto , As Jannot , R Dautry
Journal of Magnetic Resonance Imaging, 2017, 45 (6), pp.1648-1658. ⟨10.1002/jmri.25521⟩
Journal articles hal-01576042v1

Organ preservation for rectal cancer (GRECCAR 2): a prospective, randomised, open-label, multicentre, phase 3 trial

Eric Rullier , Philippe Rouanet , Jean-Jacques Tuech , Alain Valverde , Bernard Lelong
The Lancet, 2017, 390 (10093), pp.469 - 479. ⟨10.1016/S0140-6736(17)31056-5⟩
Journal articles hal-01682165v1

Surgically treated oesophageal cancer developed in a radiated field: Impact on peri-operative and long-term outcomes

Sheraz Markar , Caroline Gronnier , Alain Duhamel , Hélène Behal , Jérémie Thereaux
European Journal of Cancer, 2017, 75, pp.179-189. ⟨10.1016/j.ejca.2016.12.036⟩
Journal articles hal-02050649v1

Incidence and Risk Factors Related to Symptomatic Venous Thromboembolic Events After Esophagectomy for Cancer

Styliani Mantziari , Caroline Gronnier , Arnaud Pasquer , Johan Gagnière , Jérémie Théreaux
Annals of Thoracic Surgery, 2016, ⟨10.1016/j.athoracsur.2016.03.093⟩
Journal articles hal-01563338v1
Image document

Diffuse malignant peritoneal mesothelioma: Evaluation of systemic chemotherapy with comprehensive treatment through the RENAPE Database Multi-Institutional Retrospective Study *, on behalf of the French Network for Rare Peritoneal Malignancies (RENAPE)

V Kepenekian , D Elias , G Passot , E Mery , D Goere
European Journal of Cancer, 2016, 65, pp.69-79. ⟨10.1016/j.ejca.2016.06.002⟩
Journal articles inserm-01368938v1

A new internet tool to report peritoneal malignancy extent. PeRitOneal MalIgnancy Stage Evaluation (PROMISE) application

L. Villeneuve , A. Thivolet , N. Bakrin , F. Mohamed , S. Isaac
EJSO - European Journal of Surgical Oncology, 2016, 42 (6), pp.877-882. ⟨10.1016/j.ejso.2016.03.015⟩
Journal articles hal-02297723v1

Prognostic and Therapeutic Markers in Chordomas: A Study of 287 Tumors

Arnault Tauziède-Espariat , Damien Bresson , Marc Polivka , Schahrazed Bouazza , François Labrousse
Journal of Neuropathology and Experimental Neurology, 2016, 75 (2), pp.111-120. ⟨10.1093/jnen/nlv010⟩
Journal articles hal-03172471v1
Image document

New Therapeutic Opportunities Based on DNA Mismatch Repair and BRAF Status in Metastatic Colorectal Cancer

Romain Cohen , Magali Svrcek , Chantal Dreyer , Pascale Cervera , Alex Duval
Current Oncology Reports, 2016, 18 (3), pp.18. ⟨10.1007/s11912-016-0504-2⟩
Journal articles hal-01310853v1

Early Enteral Versus Total Parenteral Nutrition in Patients Undergoing Pancreaticoduodenectomy: A Randomized Multicenter Controlled Trial (Nutri-DPC)

Julie Perinel , Christophe Mariette , Bertrand Dousset , Igor Sielezneff , Alain Gainant
Annals of Surgery, 2016, 264, pp.731-737
Journal articles hal-01466785v1

Role of neoadjuvant treatment in clinical T2N0M0 oesophageal cancer: results from a retrospective multi-center European study

Sheraz Markar , Caroline Gronnier , Arnaud Pasquer , Alain Duhamel , Hélène Beal
European Journal of Cancer, 2016, 56, pp.59-68. ⟨10.1016/j.ejca.2015.11.024⟩
Journal articles hal-01666517v1

Cytoreductive Surgery Combined with Hyperthermic Intraperitoneal Chemotherapy with Oxaliplatin Increases the Risk of Postoperative Hemorrhagic Complications: Analysis of Predictive Factors

T. Charrier , G. Passot , Julien Péron , C. Maurice , S. Gocevska
Annals of Surgical Oncology, 2016, 23, pp.2315-22. ⟨10.1245/s10434-016-5143-1⟩
Journal articles hal-02016407v1

Radio-frequency plasma polymerized biodegradable carrier for in vivo release of cis-platinum

Sudhir Bhatt , Fatemeh Valamanesh , Jérôme Pulpytel , Rea Lo Dico , Alibi Baitukha
Oncotarget, 2016, 7 (36), pp.58121-58132. ⟨10.18632/oncotarget.10932⟩
Journal articles hal-01414836v1
Image document

Activated protein C upregulates ovarian cancer cell migration and promotes unclottability of the cancer cell microenvironment

Hamda Althawadi , Halema Alfarsi , Samaher Besbes , Shahsoltan Mirshahi , Elodie Ducros
Oncology Reports, 2015, 34 (2), pp.603-609. ⟨10.3892/or.2015.4061⟩
Journal articles hal-03123258v1

Hypertension Accelerates the Progression of Alzheimer-Like Pathology in a Mouse Model of the Disease

Diana Cifuentes , Marine Poittevin , Ekrem Dere , Dong Broqueres-You , Philippe Bonnin
Hypertension, 2015, 65 (1), pp.218+. ⟨10.1161/HYPERTENSIONAHA.114.04139⟩
Journal articles hal-01545785v1

Professional risks when carrying out cytoreductive surgery for peritoneal malignancy with hyperthermic intraperitoneal chemotherapy (HIPEC): A French multicentric survey

G. Ferron , L. Simon , F. Guyon , O. Glehen , D. Goéré
EJSO - European Journal of Surgical Oncology, 2015, 41 (10), pp.1361-1367. ⟨10.1016/j.ejso.2015.07.012⟩
Journal articles hal-02334165v1

Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for First Relapse of Ovarian Cancer.

Jean-Marc Classe , Olivier Glehen , Evelyne Decullier , Jean Marc Bereder , Simon Msika
Anticancer Research, 2015, 35 (9), pp.4997-5005
Journal articles hal-02326390v1

Extra-intestinal malignancies in inflammatory bowel diseases: An update with emphasis on MDCT and MR imaging features.

A Dohan , S A Faraoun , M Barral , Y Guerrache , M Boudiaf
Diagnostic and Interventional Imaging, 2015, 96 (9), pp.871-883. ⟨10.1016/j.diii.2015.02.009⟩
Journal articles hal-01140967v1

The Lauren classification highlights the role of epithelial-to-mesenchymal transition in gastric carcinogenesis: an immunohistochemistry study of the STAT3 and adhesion molecules expression

Sergiu Susman , Raphaëlle Barnoud , Frederique Bibeau , Francesco Borini , Marc Pocard
Journal of Gastrointestinal and Liver Diseases, 2015, 24 (1), pp.77-83. ⟨10.15403/jgld.2014.1121.sus⟩
Journal articles hal-02283324v1

Dietary exposure in utero and during lactation to a mixture of genistein and an anti-androgen fungicide in a rat mammary carcinogenesis model

Pascal Phrakonkham , J.P. Brouland , H.E. Saad , Raymond Berges , C. Pimpie
Reproductive Toxicology, 2015, 54, pp.101-109. ⟨10.1016/j.reprotox.2014.05.016⟩
Journal articles hal-01207468v1

Practice patterns in complex ventral hernia repair and place of biological grafts: a national survey among French digestive academic surgeons

C Mariette , P Wind , Micelli Lupinacci , C Tresallet , M Adham
Journal of Visceral Surgery, 2014, 151 (1), pp.9-16. ⟨10.1016/j.jviscsurg.2013.12.001⟩
Journal articles hal-03269731v1
Image document

Intra-abdominal benign multicystic peritoneal mesothelioma.

Ingrid Jouvin , Anthony Dohan , P. Gergi , Marc Pocard
Journal of Visceral Surgery, 2014, epub ahead of print. ⟨10.1016/j.jviscsurg.2013.12.014⟩
Journal articles inserm-00937139v1

Peritoneal carcinomatosis treated with cytoreductive surgery and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for advanced ovarian carcinoma: A French multicentre retrospective cohort study of 566 patients.

Naoual Bakrin , Jean-Marc Bereder , Evelyne Decullier , Jean-Marc Classe , Simon Msika
EJSO - European Journal of Surgical Oncology, 2013, 39 (12), pp.1435-1443. ⟨10.1016/j.ejso.2013.09.030⟩
Journal articles hal-00919879v1
Image document

Inhaled nitric oxide reduces brain damage by collateral recruitment in a neonatal stroke model.

Christiane Charriaut-Marlangue , Philippe Bonnin , Abdallah Gharib , Pierre-Louis Leger , Sonia Villapol
Stroke, 2012, 43 (11), pp.3078-84. ⟨10.1161/STROKEAHA.112.664243⟩
Journal articles inserm-00740744v1

Pravastatin inhibits the Rho/CCN2/extracellular matrix cascade in human fibrosis explants and improves radiation-induced intestinal fibrosis in rats

V. Haydont , C. Bourgier , M. Pocard , A. Lusinchi , J. Aigueperse
Clinical Cancer Research, 2007, 13 (18), pp.5331-5340. ⟨10.1158/1078-0432.CCR-07-0625⟩
Journal articles hal-03015590v1