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Mario Gomes-Pereira

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MBNL‐dependent impaired development within the neuromuscular system in myotonic dystrophy type 1

Julie Tahraoui-Bories , Antoine Mérien , Anchel González-Barriga , Jeanne Lainé , Céline Leteur
Neuropathology and Applied Neurobiology, 2023, 49 (1), ⟨10.1111/nan.12876⟩
Journal articles hal-03992575v1
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DM1 Transgenic Mice Exhibit Abnormal Neurotransmitter Homeostasis and Synaptic Plasticity in Association with RNA Foci and Mis-Splicing in the Hippocampus

Brigitte Potier , Louison Lallemant , Sandrine Parrot , Aline Huguet-Lachon , Geneviève Gourdon
International Journal of Molecular Sciences, 2022, 23 (2), pp.592. ⟨10.3390/ijms23020592⟩
Journal articles hal-03542361v1
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Myotonic dystrophy RNA toxicity alters morphology, adhesion and migration of mouse and human astrocytes

Diana Dincã , Louison Lallemant , Anchel González-Barriga , Noémie Cresto , Sandra Braz
Nature Communications, 2022, 13 (1), pp.3841. ⟨10.1038/s41467-022-31594-9⟩
Journal articles hal-03715682v1
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Chronic Exposure to Cadmium and Antioxidants Does Not Affect the Dynamics of Expanded CAG•CTG Trinucleotide Repeats in a Mouse Cell Culture System of Unstable DNA

Mário Gomes-Pereira , Darren G Monckton
Frontiers in Cellular Neuroscience, 2021, 14, pp.606331. ⟨10.3389/fncel.2020.606331⟩
Journal articles hal-03148527v1
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Integrative Cell Type-Specific Multi-Omics Approaches Reveal Impaired Programs of Glial Cell Differentiation in Mouse Culture Models of DM1

Anchel González-Barriga , Louison Lallemant , Diana M Dincã , Sandra O Braz , Hélène Polvèche
Frontiers in Cellular Neuroscience, 2021, 15, pp.662035. ⟨10.3389/fncel.2021.662035⟩
Journal articles hal-03235993v1
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Defects in Mouse Cortical Glutamate Uptake Can Be Unveiled In Vivo by a Two-in-One Quantitative Microdialysis

Sandrine Parrot , Alex Corscadden , Louison Lallemant , Hélène Benyamine , Jean-Christophe Comte
ACS Chemical Neuroscience, 2021, 13 (1), pp.134 - 142. ⟨10.1021/acschemneuro.1c00634⟩
Journal articles hal-03753548v1
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Real Time Videomicroscopy and Semiautomated Analysis of Brain Cell Culture Models of Trinucleotide Repeat Expansion Diseases

Sandra O Braz , Diana M Dinca , Geneviève Gourdon , Mário Gomes-Pereira
Methods in Molecular Biology, 2019, Trinucleotide Repeats. Methods and Protocols, 2056, pp.217 - 240. ⟨10.1007/978-1-4939-9784-8_14⟩
Journal articles hal-03753559v1
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Of Mice and Men: Advances in the Understanding of Neuromuscular Aspects of Myotonic Dystrophy

Sandra O Braz , Julien Acquaire , Geneviève Gourdon , Mário Gomes-Pereira
Frontiers in Neurology, 2018, 9, ⟨10.3389/fneur.2018.00519⟩
Journal articles hal-03753310v1
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Downregulation of the Glial GLT1 Glutamate Transporter and Purkinje Cell Dysfunction in a Mouse Model of Myotonic Dystrophy

Géraldine Sicot , Laurent Servais , Diana Dinca , Axelle M Leroy , Cynthia Prigogine
Cell Reports, 2017, 19 (13), pp.2718-2729. ⟨10.1016/j.celrep.2017.06.006⟩
Journal articles hal-03164812v1
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Ethidium Bromide Modifies The Agarose Electrophoretic Mobility of CAG•CTG Alternative DNA Structures Generated by PCR

Mário Gomes-Pereira , Darren G Monckton
Frontiers in Cellular Neuroscience, 2017, 11, ⟨10.3389/fncel.2017.00153⟩
Journal articles hal-03164849v1

Disease-associated CAG{middle dot}CTG triplet repeats expand rapidly in non-dividing mouse cells, but cell cycle arrest is insufficient to drive expansion

Mário Gomes-Pereira , J. Hilley , F. Morales , B. Adam , H. James
Nucleic Acids Research, 2014, 42 (11), pp.7047-7056. ⟨10.1093/nar/gku285⟩
Journal articles hal-03164860v1

Non-Radioactive Detection of Trinucleotide Repeat Size Variability

Stéphanie Tomé , Annie Nicole , Mario Gomes-Pereira , Genevieve Gourdon
Journal articles hal-03545527v1
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Myotonic dystrophy CTG expansion affects synaptic vesicle proteins, neurotransmission and mouse behaviour.

Oscar Hernández-Hernández , Céline Guiraud-Dogan , Géraldine Sicot , Aline Huguet , Sabrina Luilier
Brain - A Journal of Neurology , 2013, 136 (Pt 3), pp.957-70. ⟨10.1093/brain/aws367⟩
Journal articles inserm-00795195v1

Molecular, Physiological, and Motor Performance Defects in DMSXL Mice Carrying > 1,000 CTG Repeats from the Human DM1 Locus

Aline Huguet , Fadia Medja , Annie Nicole , Alban Vignaud , Celine Guiraud-Dogan
PLoS Genetics, 2012, 8 (11), pp.e1003043. ⟨10.1371/journal.pgen.1003043⟩
Journal articles hal-01544072v1
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DM1 CTG expansions affect insulin receptor isoforms expression in various tissues of transgenic mice

Céline Guiraud-Dogan , Aline Huguet , Mário Gomes-Pereira , Edith Brisson , Guillaume Bassez
Biochimica et Biophysica Acta - Molecular Basis of Disease, 2007, 1772 (11-12), pp.1183. ⟨10.1016/j.bbadis.2007.08.004⟩
Journal articles hal-00501551v1

Toxic RNA and glial cell pathology: deciphering brain dysfunction in myotonic dystrophy

Mário Gomes-Pereira
9th Molecular and Cell Biology Symposium, Feb 2023, Porto, Portugal
Conference papers hal-04007409v1

Dystrophie myotonique: de la pathophysiologie aux approaches thérapeutiques

Mário Gomes-Pereira , Arnaud F Klein
Société Française de Thérapie Cellulaire et Génique, Apr 2022, Webinar, France
Conference papers hal-04007420v1

Glial cell dysfunction in myotonic dystrophy brain disease

Dm Dinca , So Braz , Louison Lallemant , A Gonzalez-Barriga , B Potier
12th Japanese-French Workshop: New insights in personalized medicine for neuromuscular diseases: From Basic to Applied Myology, Sep 2022, Giverny, France
Conference papers hal-04004421v1

Myotonic dystrophy type 1: from DNA repeat expansion and toxic RNA to the development of new therapeutic approaches

Mário Gomes-Pereira , Arnaud F Klein
European reference network for rare and low prevalence complex diseases, Jul 2022, Webinar, France
Conference papers hal-04007414v1

Astrocytes, the unusual suspects in myotonic dystrophy

Mário Gomes-Pereira
Seminar, Institute for Stem Cell and Exploration of Monogenic Diseases (I-STEM), May 2021, Evry, France
Conference papers hal-04007468v1

Myotonic dystrophy: Toxic RNA and glia cell disease

Mário Gomes-Pereira
Seminar, Radboud University, May 2021, Radboud, Netherlands
Conference papers hal-04007513v1

Real-time monitoring of brain cell models for neuromuscular and neurodegenerative disorders

A Gonzalez-Barriga , D Dinca , So Braz , Geneviève Gourdon , Mário Gomes-Pereira
Incucyte User Meeting, Nov 2019, Paris, France
Conference papers hal-04003539v1

Mouse models of brain disease in myotonic dystrophy

Mário Gomes-Pereira
ENMC International Workshop on Myotonic Dystrophies, Oct 2019, Amsterdam, Netherlands
Conference papers hal-04003506v1

Investigating oligodendrocyte dysfunction in DM1 brain disease

So Braz , Aline Huguet-Lachon , C Chhuon , A Schmitt , C Guerrera
4th Congress of the Young Researchers of Imagine Institute, May 2018, Paris, France
Conference papers hal-04003498v1

Investigating oligodendrocyte dysfunction in DM1 brain disease

So Braz , Aline Huguet-Lachon , C Chhuon , A Schmitt , C Guerrera
International Conference on Unstable Microsatellites and Human Disease, Apr 2018, Capri (IT), Italy
Conference papers hal-04003486v1

CUG RNA toxicity in astrocytes is associated with adhesion and migration deficits and affects neuritogenesis

D Dinca , G Sicot , Aline Huguet-Lachon , So Braz , C Chhuon
International Myotonic Dystrophy consortium Meeting 11, Sep 2017, San Francisco (CA, USA), United States
Conference papers hal-04003470v1

Investigating oligodendrocyte dysfunction in DM1 brain disease

Sandra Braz , Diana Dinca , Aline Huguet-Lachon , Geneviève Gourdon , Mário Gomes-Pereira
Imagine Young Researcher Seminars, Feb 2017, Paris, France
Conference papers hal-04001598v1

Investigating the mechanisms of brain disease in a mouse model of myotonic dystrophy

Diana Dinca , Sandra Braz , Geneviève Gourdon , Mário Gomes-Pereira
MDRU meeting, Mar 2017, Munich, Germany
Conference papers hal-04001746v1

Abnormal neuroglial interactions in myotonic dystrophy

Diana Dinca , Géraldine Sicot , Aline Huguet-Lachon , Noémie Gueriba , Geneviève Gourdon
 Young Researchers in Life Sciences, May 2017, Paris, France
Conference papers hal-04001772v1

Cytoskeleton abnormalities triggered by toxic CUG RNA repeats in DM1 astrocytes.

Paul Magneron , Louison Lallemant , Luis Guillermo Correa Parra , Mário Gomes-Pereira , Geneviève Gourdon
NeuroFrance, May 2023, Lyon20, France
Conference poster hal-04005541v1

DM1 transgenic mice exhibit abnormal neurotransmitter homeostasis and synaptic plasticity in association with RNA mis-splicing in the hippocampus.

B Potier , Louison Lallemant , Sandrine Parrot , Aline Huguet-Lachon , Geneviève Gourdon
NeuroFrance, May 2023, Lyon, France
Conference poster hal-04005556v1

Toxic CUG RNA repeats disrupt developmentally-regulated splicing in oligodendrocytes causing transient hypomyelination in a mouse model of myotonic dystrophy.

Louison Lallemant , Sandra Braz , Anchel González-Barriga , Paul Magneron , Aurélien Cordier
The European Meeting on Glial Cells in Health and Disease, Jul 2023, Berlin, France
Conference poster hal-04005524v1

Defects in mouse cortical glutamate uptake can be unveiled in vivo by a two-in-one quantitative microdialysis.

Alex Corscadden , Louison Lallemant , Hélène Benyamine , Jean-Christophe Comte , Aline Huguet-Lachon
NeuroFrance, May 2023, Lyon, France
Conference poster hal-04005564v1

Cytoskeleton abnormalities triggered by toxic CUG RNA repeats in DM1 astrocytes.

Paul Magneron , Louison Lallemant , Luis Guillermo Correa Parra , Geneviève Gourdon , Mário Gomes-Pereira
French Glial Cell Club, May 2023, Lyon, France
Conference poster hal-04005531v1

Myotonic dystrophy RNA toxicity alters morphology, adhesion and migration of mouse and human astrocytes

Diana Mihaela Dincã , Louison Lallemant , Anchel González-Barriga , Noemie Cresto , Sandra Braz
International Myotonic Dystrophy Consortium Meeting, Jun 2022, Osaka, Japan
Conference poster hal-04006873v1

Toxic RNA impairs synaptic function and vesicle transport in myotonic dystrophy type 1.

Louison Lallemant , B Potier , Baptiste Grimaud , Sandra Braz , Diana Mihaela Dincã
Mechanisms of Neuronal Connectivity Meeting, Sep 2022, New York (NY), France
Conference poster hal-04005617v1

Defects in mouse cortical glutamate uptake can be unveiled in vivo by a two-in-one quantitative microdialysis.

Alex Corscadden , Louison Lallemant , Hélène Benyamine , Jean-Christophe Comte , Aline Huguet-Lachon
Monitoring Molecules in Neuroscience, Jun 2022, Lyon, France
Conference poster hal-04006970v1
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DM1 transgenic mice exhibit abnormal neurotransmitter homeostasis and synaptic plasticity in association with RNA mis-splicing in the hippocampus

Brigitte Potier , Louison Lallemant , Sandrine Parrot , Aline Huguet-Lachon , Geneviève Gourdon
18th International Conference - Monitoring Molecules in Neuroscience, Jun 2022, Lyon, France. , ⟨10.3390/ijms2302059⟩
Conference poster hal-04006990v1

MBNL-dependent impaired development connectivity within neuromuscular circuits in myotonic dystrophy type 1

Julie Tahraoui-Bories , Antoine Mérien , Florine Roussange , Anchel González-Barriga , Jeanne Lainé
International Myotonic Dystrophy Consortium Meeting, Jun 2022, Osaka, Japan
Conference poster hal-04006954v1

MBNL dependent-impaired development connectivity within neuromuscular circuits in Myotonic Dystrophy type.

Julie Tahraoui-Bories , Antoine Mérien , Jeanne Lainé , Florine Roussange , Anchel González-Barriga
Myology 2022, Sep 2022, Nice, France
Conference poster hal-04005593v1

Study of axonal transport in myotonic dystrophy Type 1

Lallemant Louison , Gourdon Genevieve , Mário Gomes-Pereira
Journée Boris Ephrussi, May 2021, Paris, France
Conference poster hal-04009795v1

RNA toxicity in myotonic dystrophy causes pronounced spliceopathy in astrocytes, in association with defective cell adhesion and morphology, erratic migration and impaired polarization

Diana Mihaela Dincã , Anchel González-Barriga , Sandra Braz , Laure-Elise Pillet , Noémie Cresto
Cold Spring Harbor Laboratory Meeting on Glia in Health and Disease, Jul 2020, Cold Spring Harbor (New York), United States
Conference poster hal-04009836v1

Investigating oligodendrocyte dysfunction in DM1 brain disease

Sandra Braz , Raphael Blain , Cyril F Bourgeois , Aline Huguet-Lachon , Alain Schmitt
The European Meeting on Glial Cells in Health and Disease, Jul 2019, Porto, Portugal
Conference poster hal-04010005v1

Toxic RNA affects astrocyte adhesion, spreading and migration in myotonic dystrophy, and impacts neuritogenesis through abnormal glial-neuronal interactions

Diana Mihaela Dincã , Anchel González-Barriga , Sandra Braz , Cyril F Bourgeois , Géraldine Sicot
The European Meeting on Glial Cells in Health and Disease, Jul 2019, Porto, Portugal
Conference poster hal-04009975v1

Glutamate dysfunction at extrasynaptic site in hippocampus of mice model of myotonic dystrophy type 1 (DM1) disease

B Potier , Aline Huguet-Lachon , Geneviève Gourdon , Mário Gomes-Pereira , Patrick Dutar
NeuroFrance, May 2019, Marseille, France
Conference poster hal-04009926v1

Combination of Omics Approaches to Study Molecular Abnormalities in Individual Brain Cell Types of a DM1 Mouse Model

Anchel González-Barriga , Diana Mihaela Dincã , Sandra Braz , Aurélien Cordier , Cerina Chhuon
International Myotonic Dystrophy Consortium Meeting (IDMC-12), Jun 2019, Gothenburg, Sweden.
Conference poster hal-04009963v1

Upregulation of glial GLT1 glutamate transporter corrects Purkinje cell dysfunction and cerebellum-dependent motor incoordination in a mouse model of myotonic dystrophy

Diana Mihaela Dincã , Laurent Servais , Géraldine Sicot , Axelle Leroy , Cynthia Prigogine
SAB Meeting, Apr 2017, Paris, France
Conference poster hal-04010282v1

Impact of the CTG repeat expansion on neuronal and astroglial physiology in myotonic dystrophy

Diana Mihaela Dincã , Géraldine Sicot , Aline Huguet-Lachon , Noémie Gueriba , Geneviève Gourdon
Colloque des Jeunes Chercheurs, Jun 2017, Paris, France
Conference poster hal-04010254v1