Saida MEBAREK

Documents

Affiliations actuelles

Institut de Chimie et Biochimie Moléculaires et Supramoléculaires (ICBMS)
Institut National des Sciences Appliquées (INSA)
Université Claude Bernard Lyon 1 (UCBL)
Centre National de la Recherche Scientifique (CNRS)
École Supérieure de Chimie Physique Électronique de Lyon (CPE)

Compétences

métabolisme lipidique

Publications

	Assessment of a beta-metastable titanium alloy for orthopedic use: Corrosion in biomimetic synovial fluid and biocompatibility Paulo Vitor Fedri Carvalho , Lea Cassulino , Hugo Forest , Doina-Margareta Gordin , Thierry Granjon et al. Journal of Materials Research and Technology, 2026, 42, pp.3737-3752. ⟨10.1016/j.jmrt.2026.04.052⟩ Article dans une revue hal-05622146v1
	Blocking Sphingosine 1‐phosphate Metabolism With Fingolimod Prevents the Progression of Vascular Smooth Muscle Cells Calcification in Chronic Kidney Disease Najwa Skafi , Solenne Pelletier , Christophe Soulage , Sarah Nahle , Beatriz da Cruz et al. Journal of Cellular Physiology, 2026, 241 (1), ⟨10.1002/jcp.70137⟩ Article dans une revue hal-05469143v1
	Liposome‐Based Potential Vaccines Platforms that Are Noncytotoxic Saida Mebarek , Killian Jacob , Carmela Ilaria Pierro , Davide Romanini , Michele Fiore ChemistryOpen, 2026, 15 (1), ⟨10.1002/open.202500530⟩ Article dans une revue hal-05461295v1
	Strontium Changes Lipid Profile, Release, and Function of Matrix Vesicles Produced by Mineralization-Competent Cells Larwsk Null Hayann , Mairobys Null Socorro , Adriana Ferreira Lopes Null Vilela , Juçara Gastaldi Null Cominal , Luiz Henrique da Silva Null Andrilli et al. Frontiers in Bioscience-Landmark, 2025, 30 (12), pp.47664. ⟨10.31083/FBL47664⟩ Article dans une revue hal-05445251v1
	Modulation of TNAP activity and apatite formation in biomimetic matrix vesicles studied by 31P solid-state NMR B.Z. Favarin , N. Nassif , T. Azaïs , J. Guignier , S. Mebarek et al. Biochimica et Biophysica Acta:Biomembranes, 2025, 1867 (8), pp.184446. ⟨10.1016/j.bbamem.2025.184446⟩ Article dans une revue hal-05296725v1
	Cathepsin K Inhibitors as Potential Drugs for the Treatment of Osteoarthritis Leyre Brizuela , Rene Buchet , Carole Bougault , Saida Mebarek International Journal of Molecular Sciences, 2025, 26 (7), pp.2896. ⟨10.3390/ijms26072896⟩ Article dans une revue hal-05186321v1
	A protein corona modulates the function of mineralization-competent matrix vesicles Juçara Gastaldi Cominal , Heitor Gobbi Sebinelli , Larwsk Hayann , Lucas Fabrício Bahia Nogueira , Marcos Antonio Eufrásio Cruz et al. JBMR Plus, 2025, 9 (2), ⟨10.1093/jbmrpl/ziae168⟩ Article dans une revue hal-04942759v1
	Space radiation damage rescued by inhibition of key spaceflight associated miRNAs J. Tyson Mcdonald , Jangkeun Kim , Lily Farmerie , Meghan Johnson , Nidia Trovao et al. Nature Communications, 2024, 15 (1), pp.4825. ⟨10.1038/s41467-024-48920-y⟩ Article dans une revue hal-04626278v1
	Brazil nut–enriched diet modulates bone mineral density and body composition in an experimental model of chronic kidney disease Beatriz Oliveira da Cruz , Patricia Pereira Almeida , Nathalia Silva-Costa , Michele Lima Brito , Viviane Alexandre Nunes Degani et al. Nutrition, 2024, 125, pp.112482. ⟨10.1016/j.nut.2024.112482⟩ Article dans une revue hal-04942776v1
	The surface proteomic profile of serum extracellular vesicles as a diagnostic and prognostic tool in breast cancer Giada Corti , Rene Buchet , Andrea Magrini , Pietro Ciancaglini , Saida Mebarek et al. Current Opinion in Physiology, 2024, 37, pp.100734. ⟨10.1016/j.cophys.2023.100734⟩ Article dans une revue hal-05445261v1
	Positive impact of pyrocarbon and mechanical loading on cartilage-like tissue synthesis in a scaffold-free process Imbert de Gaudemaris , Amira Hannoun , Rémy Gauthier , Nina Attik , Leyre Brizuela et al. Journal of Bioscience and Bioengineering, 2024, 139 (1), pp.53-59. ⟨10.1016/j.jbiosc.2024.09.005⟩ Article dans une revue hal-04733370v1
	NOT ALL EXTRACELLULAR VESICLES ARE MADE EQUAL: COMPARISON OF MATRIX BINDING AND MEDIA VESICLES FOR HARD TISSUE REGENERATION G. Anghileri , W. Devoogt , C.S. Seinen , S. Mebarek , P. Vader et al. Cytotherapy, 2024, 26 (6), pp.S74. ⟨10.1016/j.jcyt.2024.03.133⟩ Article dans une revue hal-05445276v1
	Targeting Sphingosine 1-Phosphate Metabolism as a Therapeutic Avenue for Prostate Cancer Saida Mebarek , Najwa Skafi , Leyre Brizuela Cancers, 2023, 15 (10), pp.2732. ⟨10.3390/cancers15102732⟩ Article dans une revue hal-04948262v1
	Do Media Extracellular Vesicles and Extracellular Vesicles Bound to the Extracellular Matrix Represent Distinct Types of Vesicles? Saida Mebarek , Rene Buchet , Slawomir Pikula , Agnieszka Strzelecka-Kiliszek , Leyre Brizuela et al. Biomolecules, 2023, 14 (1), pp.42. ⟨10.3390/biom14010042⟩ Article dans une revue hal-04948247v1
	Microwave‐Assisted Syntheses of Rhodamine, Rhodol, and Fluorescein Derivatives Carolina Chieffo , Emiliano Altamura , Guillaume Pilet , Saida Mebarek , Peter Strazewski et al. ChemPlusChem, 2023, 88 (7), ⟨10.1002/cplu.202300189⟩ Article dans une revue hal-04942792v1
	Nano/micro implant debris affect osteogenesis by chondrocytes: Comparison between ceramic and UHMWPE from hip walking simulator Marwa Ben Braham , Ana-Maria Trunfio-Sfarghiu , Leyre Brizuela , Saida Mebarek , Ines Essefi et al. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2022, 110 (2), pp.338-349. ⟨10.1002/jbm.b.34910⟩ Article dans une revue hal-03659792v1
	Shedding Light on the Role of Na,K-ATPase as a Phosphatase during Matrix-Vesicle-Mediated Mineralization Heitor Gobbi Sebinelli , Luiz Henrique Silva Andrilli , Bruno Zoccaratto Favarin , Marcos Aantonio Eufrasio Cruz , Maytê Bolean et al. International Journal of Molecular Sciences, 2022, 23 (23), pp.15072. ⟨10.3390/ijms232315072⟩ Article dans une revue hal-04942795v1
	Prostate cancer-derived exosomes promote osteoblast differentiation and activity through phospholipase D2 Mathieu Borel , Giovanna Lollo , David Magne , René Buchet , Leyre Brizuela et al. Biochimica et Biophysica Acta - Molecular Basis of Disease, 2020, 1866 (12), pp.165919. ⟨10.1016/j.bbadis.2020.165919⟩ Article dans une revue hal-02925416v1
	Increased phospholipase D activity contributes to tumorigenesis in prostate cancer cell models Mathieu Borel , Olivier Cuvillier , David Magne , Saida Mebarek , Leyre Brizuela Molecular and Cellular Biochemistry, 2020, 473 (1-2), pp.263-279. ⟨10.1007/s11010-020-03827-2⟩ Article dans une revue hal-03019019v1
	The role of sphingosine 1-phosphate metabolism in bone and joint pathologies and ectopic calcification Alaeddine El Jamal , Carole Bougault , Saida Mebarek , David Magne , Olivier Cuvillier et al. BONE, 2020, 130, pp.115087 -. ⟨10.1016/j.bone.2019.115087⟩ Article dans une revue hal-03489320v1
	Phospholipase D: A new mediator during high phosphate-induced vascular calcification associated with chronic kidney disease Najwa Skafi , Dina Abdallah , Christophe Soulage , Sophie Reibel , Nicolas Vitale et al. Journal of Cellular Physiology, 2019, 234 (4), pp.4825--4839. ⟨10.1002/jcp.27281⟩ Article dans une revue hal-02195193v1
	Effects of phospholipase D during cultured osteoblast mineralization and bone formation. Dina Abdallah , Najwa Skafi , Eva Hamade , Mathieu Borel , Sophie Reibel Foisset et al. Journal of Cellular Biochemistry, 2019, 120 (4), pp.5923-5935. ⟨10.1002/jcb.27881⟩ Article dans une revue hal-02975745v1
	Involvement of phospholipase D in mineralization process in cultured osteoblasts. D. Abdallah , N. Skafi , E. Hamade , S. Reibel , N. Vitale et al. Journal of Cellular Biochemistry, 2019 Article dans une revue hal-02132504v1
	Multi-physical characterization of chondrocyte cultures in contact with different orthopaedic implants biomaterials A. Hannoun , G. Ouenzer , S. Mebarek , C. Bougault , M. Hassler et al. European Cells Materials, 2019 Article dans une revue hal-02132650v1
	Pyrocarbon versus cobalt-chromium in the context of spherical interposition implants: an in vitro study on cultured chondrocytes A Hannoun , G Ouenzerfi , L. Brizuela , S. Mebarek , C Bougault et al. eCells and Materials Journal, 2019, 37, pp.1-15. ⟨10.22203/eCM.v037a01⟩ Article dans une revue hal-02133470v1
	Multi-scale mechanical characterization of prostate cancer cell lines : relevant biological markers to evaluate the cell metastatic potential J. Zouaoui , A. Trunfio-Sfarghiu , L. Brizuela , Agnès Piednoir , O. Maniti et al. Biochimica et Biophysica Acta (BBA) - Specialized Section on Biophysical Subjects, 2017, 1861 (12), pp.3109 - 3119. ⟨10.1016/j.bbagen.2017.09.003⟩ Article dans une revue hal-01739046v1
	Involvement of sphingosine kinase/sphingosine 1-phosphate metabolic pathway in spondyloarthritis Carole Bougault , A El El Jamal , Anne Briolay , Saida Mebarek , Marie-Astrid Boutet et al. BONE, 2017, 103, pp.150 - 158. ⟨10.1016/j.bone.2017.07.002⟩ Article dans une revue inserm-01670760v1
	Synthesis of benzofuran derivatives as selective inhibitors of tissue-nonspecific alkaline phosphatase : effects on cell toxicity and osteoblast-induced mineralization S. Marques , R. Buchet , F. Popowycz , M. Lemaire , S. Mebarek Bioorganic and Medicinal Chemistry Letters, 2016, 24 (5), pp.1457-1459 Article dans une revue hal-01312906v1
	Direct determination of phosphatase activity from physiological substrates in cells Z. Ren , D. Do Le , G. Bechkoff , S. Mebarek , S. Ahamada et al. PLoS ONE, 2015, 10 (3), pp.e0120087. ⟨10.1371/journal.pone.0120087⟩ Article dans une revue hal-01414271v1
	Azanitrile cathepsin K Inhibitors : Effects on cell toxicity ; osteoblast-induced mineralization and osteoclast-mediated bone resorption Zhongyuan Ren , Irma Machuca-Gayet , Chantal Domenget , René Buchet , Yuqing Wu et al. PLoS ONE, 2015, 10 (7), pp.e0132513. ⟨10.1371/journal.pone.0132513⟩ Article dans une revue hal-01414415v1
	Inhibitors : effects on cell toxicity ; osteoblast-induced mineralization and osteoclast-mediated bone resorption. Zhong-Yuan Ren , Irma Machuca-Gayet , Chantal Domenget , Rene Buchet , Yuqing Wu et al. PLoS ONE, 2015, 10 (7), pp.e132513 Article dans une revue hal-01485048v1
	Phospholipases of mineralization competent cells and matrix vesicles: roles in physiological and pathological mineralizations. Saida Mebarek , Abdelkarim Abousalham , David Magne , Le Duy Do , Joanna Bandorowicz-Pikula et al. International Journal of Molecular Sciences, 2013, 14 (3), pp.5036-129. ⟨10.3390/ijms14035036⟩ Article dans une revue hal-00917256v1
	Direct determination of phospholipase D activity by infrared spectroscopy. Le Duy Do , René Buchet , Slawomir Pikula , Abdelkarim Abousalham , Saida Mebarek Analytical Biochemistry, 2012, 430 (1), pp.32-8. ⟨10.1016/j.ab.2012.07.017⟩ Article dans une revue istex hal-00917259v1
	Ankylosing spondylitis, late osteoarthritis, vascular calcification, chondrocalcinosis and pseudo gout: toward a possible drug therapy. S. Mebarek , E. Hamade , C. Thouverey , J. Bandorowicz-Pikula , S. Pikula et al. Current Medicinal Chemistry, 2011, 18 (14), pp.2196-203 Article dans une revue hal-00599331v1
	Necdin Plays a Role in the Serotonergic Modulation of the Mouse Respiratory Network: Implication for Prader-Willi Syndrome S. Zanella , F. Watrin , S. Mebarek , F. Marly , M. Roussel et al. Journal of Neuroscience, 2008, 28 (7), pp.1745-1755. ⟨10.1523/JNEUROSCI.4334-07.2008⟩ Article dans une revue hal-03437048v1

	Enhancing PEEK Implant Performance: Role of Hydroxyapatite Coatings and Mechanotransduction in Osseointegration and Cell Response Cérine Labadi , Nina Attik , Michal Ruzek , Clément Deschamps , Pierre Bertrand et al. 12th European Solid Mechanics Conference, Jul 2025, Lyon, France Poster de conférence hal-05346002v1

Chargement...

Saida MEBAREK

Compétences

Publications

Publications

Assessment of a beta-metastable titanium alloy for orthopedic use: Corrosion in biomimetic synovial fluid and biocompatibility

Blocking Sphingosine 1‐phosphate Metabolism With Fingolimod Prevents the Progression of Vascular Smooth Muscle Cells Calcification in Chronic Kidney Disease

Liposome‐Based Potential Vaccines Platforms that Are Noncytotoxic

Strontium Changes Lipid Profile, Release, and Function of Matrix Vesicles Produced by Mineralization-Competent Cells

Modulation of TNAP activity and apatite formation in biomimetic matrix vesicles studied by 31P solid-state NMR

Cathepsin K Inhibitors as Potential Drugs for the Treatment of Osteoarthritis

A protein corona modulates the function of mineralization-competent matrix vesicles

Space radiation damage rescued by inhibition of key spaceflight associated miRNAs

Brazil nut–enriched diet modulates bone mineral density and body composition in an experimental model of chronic kidney disease

The surface proteomic profile of serum extracellular vesicles as a diagnostic and prognostic tool in breast cancer

Positive impact of pyrocarbon and mechanical loading on cartilage-like tissue synthesis in a scaffold-free process

NOT ALL EXTRACELLULAR VESICLES ARE MADE EQUAL: COMPARISON OF MATRIX BINDING AND MEDIA VESICLES FOR HARD TISSUE REGENERATION

Targeting Sphingosine 1-Phosphate Metabolism as a Therapeutic Avenue for Prostate Cancer

Do Media Extracellular Vesicles and Extracellular Vesicles Bound to the Extracellular Matrix Represent Distinct Types of Vesicles?

Microwave‐Assisted Syntheses of Rhodamine, Rhodol, and Fluorescein Derivatives

Nano/micro implant debris affect osteogenesis by chondrocytes: Comparison between ceramic and UHMWPE from hip walking simulator

Shedding Light on the Role of Na,K-ATPase as a Phosphatase during Matrix-Vesicle-Mediated Mineralization

Prostate cancer-derived exosomes promote osteoblast differentiation and activity through phospholipase D2

Increased phospholipase D activity contributes to tumorigenesis in prostate cancer cell models

The role of sphingosine 1-phosphate metabolism in bone and joint pathologies and ectopic calcification

Phospholipase D: A new mediator during high phosphate-induced vascular calcification associated with chronic kidney disease

Effects of phospholipase D during cultured osteoblast mineralization and bone formation.

Involvement of phospholipase D in mineralization process in cultured osteoblasts.

Multi-physical characterization of chondrocyte cultures in contact with different orthopaedic implants biomaterials

Pyrocarbon versus cobalt-chromium in the context of spherical interposition implants: an in vitro study on cultured chondrocytes

Multi-scale mechanical characterization of prostate cancer cell lines : relevant biological markers to evaluate the cell metastatic potential

Involvement of sphingosine kinase/sphingosine 1-phosphate metabolic pathway in spondyloarthritis

Synthesis of benzofuran derivatives as selective inhibitors of tissue-nonspecific alkaline phosphatase : effects on cell toxicity and osteoblast-induced mineralization

Direct determination of phosphatase activity from physiological substrates in cells

Azanitrile cathepsin K Inhibitors : Effects on cell toxicity ; osteoblast-induced mineralization and osteoclast-mediated bone resorption

Inhibitors : effects on cell toxicity ; osteoblast-induced mineralization and osteoclast-mediated bone resorption.

Phospholipases of mineralization competent cells and matrix vesicles: roles in physiological and pathological mineralizations.

Direct determination of phospholipase D activity by infrared spectroscopy.

Ankylosing spondylitis, late osteoarthritis, vascular calcification, chondrocalcinosis and pseudo gout: toward a possible drug therapy.

Necdin Plays a Role in the Serotonergic Modulation of the Mouse Respiratory Network: Implication for Prader-Willi Syndrome

Enhancing PEEK Implant Performance: Role of Hydroxyapatite Coatings and Mechanotransduction in Osseointegration and Cell Response