Saida MEBAREK

30
Documents
Affiliations actuelles
  • Institut de Chimie et Biochimie Moléculaires et Supramoléculaires (ICBMS)
  • Institut National des Sciences Appliquées (INSA)
  • Université Claude Bernard Lyon 1 (UCBL)
  • Centre National de la Recherche Scientifique (CNRS)
  • École Supérieure de Chimie Physique Électronique de Lyon (CPE)

Présentation


Compétences

métabolisme lipidique

Publications

Publications

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Modulation of TNAP activity and apatite formation in biomimetic matrix vesicles studied by 31P solid-state NMR

B.Z. Favarin , N. Nassif , T. Azaïs , J. Guignier , S. Mebarek et al.
Biochimica et Biophysica Acta:Biomembranes, 2025, 1867 (8), pp.184446. ⟨10.1016/j.bbamem.2025.184446⟩
Article dans une revue hal-05296725 v1

Cathepsin K Inhibitors as Potential Drugs for the Treatment of Osteoarthritis

Leyre Brizuela , Rene Buchet , Carole Bougault , Saida Mebarek
International Journal of Molecular Sciences, 2025, 26 (7), pp.2896. ⟨10.3390/ijms26072896⟩
Article dans une revue hal-05186321 v1

A protein corona modulates the function of mineralization-competent matrix vesicles

Juçara Gastaldi Cominal , Heitor Gobbi Sebinelli , Larwsk Hayann , Lucas Fabrício Bahia Nogueira , Marcos Antonio Eufrásio Cruz et al.
JBMR Plus, 2025, 9 (2), ⟨10.1093/jbmrpl/ziae168⟩
Article dans une revue hal-04942759 v1

Positive impact of pyrocarbon and mechanical loading on cartilage-like tissue synthesis in a scaffold-free process

Imbert de Gaudemaris , Amira Hannoun , Rémy Gauthier , Nina Attik , Leyre Brizuela et al.
Journal of Bioscience and Bioengineering, 2024, 139 (1), pp.53-59. ⟨10.1016/j.jbiosc.2024.09.005⟩
Article dans une revue hal-04733370 v1

Space radiation damage rescued by inhibition of key spaceflight associated miRNAs

J. Tyson Mcdonald , Jangkeun Kim , Lily Farmerie , Meghan Johnson , Nidia Trovao et al.
Nature Communications, 2024, 15 (1), pp.4825. ⟨10.1038/s41467-024-48920-y⟩
Article dans une revue hal-04626278 v1

Brazil nut–enriched diet modulates bone mineral density and body composition in an experimental model of chronic kidney disease

Beatriz Oliveira da Cruz , Patricia Pereira Almeida , Nathalia Silva-Costa , Michele Lima Brito , Viviane Alexandre Nunes Degani et al.
Nutrition, 2024, 125, pp.112482. ⟨10.1016/j.nut.2024.112482⟩
Article dans une revue hal-04942776 v1

Targeting Sphingosine 1-Phosphate Metabolism as a Therapeutic Avenue for Prostate Cancer

Saida Mebarek , Najwa Skafi , Leyre Brizuela
Cancers, 2023, 15 (10), pp.2732. ⟨10.3390/cancers15102732⟩
Article dans une revue hal-04948262 v1

Do Media Extracellular Vesicles and Extracellular Vesicles Bound to the Extracellular Matrix Represent Distinct Types of Vesicles?

Saida Mebarek , Rene Buchet , Slawomir Pikula , Agnieszka Strzelecka-Kiliszek , Leyre Brizuela et al.
Biomolecules, 2023, 14 (1), pp.42. ⟨10.3390/biom14010042⟩
Article dans une revue hal-04948247 v1

Microwave‐Assisted Syntheses of Rhodamine, Rhodol, and Fluorescein Derivatives

Carolina Chieffo , Emiliano Altamura , Guillaume Pilet , Saida Mebarek , Peter Strazewski et al.
ChemPlusChem, 2023, 88 (7), ⟨10.1002/cplu.202300189⟩
Article dans une revue hal-04942792 v1
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Nano/micro implant debris affect osteogenesis by chondrocytes: Comparison between ceramic and UHMWPE from hip walking simulator

Marwa Ben Braham , Ana-Maria Trunfio-Sfarghiu , Leyre Brizuela , Saida Mebarek , Ines Essefi et al.
Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2022, 110 (2), pp.338-349. ⟨10.1002/jbm.b.34910⟩
Article dans une revue hal-03659792 v1

Shedding Light on the Role of Na,K-ATPase as a Phosphatase during Matrix-Vesicle-Mediated Mineralization

Heitor Gobbi Sebinelli , Luiz Henrique Silva Andrilli , Bruno Zoccaratto Favarin , Marcos Aantonio Eufrasio Cruz , Maytê Bolean et al.
International Journal of Molecular Sciences, 2022, 23 (23), pp.15072. ⟨10.3390/ijms232315072⟩
Article dans une revue hal-04942795 v1
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Prostate cancer-derived exosomes promote osteoblast differentiation and activity through phospholipase D2

Mathieu Borel , Giovanna Lollo , David Magne , René Buchet , Leyre Brizuela et al.
Biochimica et Biophysica Acta - Molecular Basis of Disease, 2020, 1866 (12), pp.165919. ⟨10.1016/j.bbadis.2020.165919⟩
Article dans une revue hal-02925416 v1

Increased phospholipase D activity contributes to tumorigenesis in prostate cancer cell models

Mathieu Borel , Olivier Cuvillier , David Magne , Saida Mebarek , Leyre Brizuela
Molecular and Cellular Biochemistry, 2020, 473 (1-2), pp.263-279. ⟨10.1007/s11010-020-03827-2⟩
Article dans une revue hal-03019019 v1
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The role of sphingosine 1-phosphate metabolism in bone and joint pathologies and ectopic calcification

Alaeddine El Jamal , Carole Bougault , Saida Mebarek , David Magne , Olivier Cuvillier et al.
BONE, 2020, 130, pp.115087 -. ⟨10.1016/j.bone.2019.115087⟩
Article dans une revue hal-03489320 v1

Phospholipase D: A new mediator during high phosphate-induced vascular calcification associated with chronic kidney disease

Najwa Skafi , Dina Abdallah , Christophe Soulage , Sophie Reibel , Nicolas Vitale et al.
Journal of Cellular Physiology, 2019, 234 (4), pp.4825--4839. ⟨10.1002/jcp.27281⟩
Article dans une revue hal-02195193 v1

Effects of phospholipase D during cultured osteoblast mineralization and bone formation.

Dina Abdallah , Najwa Skafi , Eva Hamade , Mathieu Borel , Sophie Reibel Foisset et al.
Journal of Cellular Biochemistry, 2019, 120 (4), pp.5923-5935. ⟨10.1002/jcb.27881⟩
Article dans une revue hal-02975745 v1

Multi-physical characterization of chondrocyte cultures in contact with different orthopaedic implants biomaterials

A. Hannoun , G. Ouenzer , S. Mebarek , C. Bougault , M. Hassler et al.
European Cells Materials, 2019
Article dans une revue hal-02132650 v1

Involvement of phospholipase D in mineralization process in cultured osteoblasts.

D. Abdallah , N. Skafi , E. Hamade , S. Reibel , N. Vitale et al.
Journal of Cellular Biochemistry, 2019
Article dans une revue hal-02132504 v1

Pyrocarbon versus cobalt-chromium in the context of spherical interposition implants: an in vitro study on cultured chondrocytes

A Hannoun , G Ouenzerfi , L. Brizuela , S. Mebarek , C Bougault et al.
eCells and Materials Journal, 2019, 37, pp.1-15. ⟨10.22203/eCM.v037a01⟩
Article dans une revue hal-02133470 v1

Multi-scale mechanical characterization of prostate cancer cell lines : relevant biological markers to evaluate the cell metastatic potential

J. Zouaoui , A. Trunfio-Sfarghiu , L. Brizuela , Agnès Piednoir , O. Maniti et al.
Biochimica et Biophysica Acta (BBA) - Specialized Section on Biophysical Subjects, 2017, 1861 (12), pp.3109 - 3119. ⟨10.1016/j.bbagen.2017.09.003⟩
Article dans une revue hal-01739046 v1
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Involvement of sphingosine kinase/sphingosine 1-phosphate metabolic pathway in spondyloarthritis

Carole Bougault , A El El Jamal , Anne Briolay , Saida Mebarek , Marie-Astrid Boutet et al.
BONE, 2017, 103, pp.150 - 158. ⟨10.1016/j.bone.2017.07.002⟩
Article dans une revue inserm-01670760 v1

Synthesis of benzofuran derivatives as selective inhibitors of tissue-nonspecific alkaline phosphatase : effects on cell toxicity and osteoblast-induced mineralization

S. Marques , R. Buchet , F. Popowycz , M. Lemaire , S. Mebarek
Bioorganic and Medicinal Chemistry Letters, 2016, 24 (5), pp.1457-1459
Article dans une revue hal-01312906 v1
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Direct determination of phosphatase activity from physiological substrates in cells

Z. Ren , D. Do Le , G. Bechkoff , S. Mebarek , S. Ahamada et al.
PLoS ONE, 2015, 10 (3), pp.e0120087. ⟨10.1371/journal.pone.0120087⟩
Article dans une revue hal-01414271 v1
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Azanitrile cathepsin K Inhibitors : Effects on cell toxicity ; osteoblast-induced mineralization and osteoclast-mediated bone resorption

Zhongyuan Ren , Irma Machuca-Gayet , Chantal Domenget , René Buchet , Yuqing Wu et al.
PLoS ONE, 2015, 10 (7), pp.e0132513. ⟨10.1371/journal.pone.0132513⟩
Article dans une revue hal-01414415 v1

Inhibitors : effects on cell toxicity ; osteoblast-induced mineralization and osteoclast-mediated bone resorption.

Zhong-Yuan Ren , Irma Machuca-Gayet , Chantal Domenget , Rene Buchet , Yuqing Wu et al.
PLoS ONE, 2015, 10 (7), pp.e132513
Article dans une revue hal-01485048 v1

Phospholipases of mineralization competent cells and matrix vesicles: roles in physiological and pathological mineralizations.

Saida Mebarek , Abdelkarim Abousalham , David Magne , Le Duy Do , Joanna Bandorowicz-Pikula et al.
International Journal of Molecular Sciences, 2013, 14 (3), pp.5036-129. ⟨10.3390/ijms14035036⟩
Article dans une revue hal-00917256 v1

Direct determination of phospholipase D activity by infrared spectroscopy.

Le Duy Do , René Buchet , Slawomir Pikula , Abdelkarim Abousalham , Saida Mebarek
Analytical Biochemistry, 2012, 430 (1), pp.32-8. ⟨10.1016/j.ab.2012.07.017⟩
Article dans une revue istex hal-00917259 v1

Ankylosing spondylitis, late osteoarthritis, vascular calcification, chondrocalcinosis and pseudo gout: toward a possible drug therapy.

S. Mebarek , E. Hamade , C. Thouverey , J. Bandorowicz-Pikula , S. Pikula et al.
Current Medicinal Chemistry, 2011, 18 (14), pp.2196-203
Article dans une revue hal-00599331 v1

Necdin Plays a Role in the Serotonergic Modulation of the Mouse Respiratory Network: Implication for Prader-Willi Syndrome

S. Zanella , F. Watrin , S. Mebarek , F. Marly , M. Roussel et al.
Journal of Neuroscience, 2008, 28 (7), pp.1745-1755. ⟨10.1523/JNEUROSCI.4334-07.2008⟩
Article dans une revue hal-03437048 v1