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Michel Cogné

10
Documents

Présentation

Domaines de recherche


Compétences

Immunologie Génétique

Publications

"Alleles"

Cross talk between immunoglobulin heavy-chain transcription and RNA surveillance during B cell development.

Aurélien Tinguely , Guillaume Chemin , Sophie Péron , Christophe Sirac , Stéphane Reynaud
Molecular and Cellular Biology, 2012, 32 (1), pp.107-17. ⟨10.1128/MCB.06138-11⟩
Article dans une revue hal-00696497v1

Multiple RNA surveillance mechanisms cooperate to reduce the amount of nonfunctional Ig kappa transcripts.

Guillaume Chemin , Aurélien Tinguely , Christophe Sirac , Fabien Lechouane , Sophie Duchez
Journal of Immunology, 2010, 184 (9), pp.5009-17. ⟨10.4049/jimmunol.0902949⟩
Article dans une revue hal-00511941v1

Interallelic class switch recombination can reverse allelic exclusion and allow trans-complementation of an IgH locus switching defect.

Hei-Lanne Dougier , Stéphane Reynaud , Eric Pinaud , Claire Carrion , Laurent Delpy
European Journal of Immunology, 2006, 36 (8), pp.2181-91. ⟨10.1002/eji.200535529⟩
Article dans une revue hal-00088115v1

Interallelic class switch recombination contributes significantly to class switching in mouse B cells.

Stéphane Reynaud , Laurent Delpy , Laurence Fleury , Hei-Lanne Dougier , Christophe Sirac
Journal of Immunology, 2005, 174 (10), pp.6176-83
Article dans une revue hal-00458866v1

Transcription-dependent somatic hypermutation occurs at similar levels on functional and nonfunctional rearranged IgH alleles.

Laurent Delpy , Christophe Sirac , Caroline Le Morvan , Michel Cogné
Journal of Immunology, 2004, 173 (3), pp.1842-8
Article dans une revue hal-00023372v1

RNA surveillance down-regulates expression of nonfunctional kappa alleles and detects premature termination within the last kappa exon.

Laurent Delpy , Christophe Sirac , Emmanuelle Magnoux , Sophie Duchez , Michel Cogné
Proceedings of the National Academy of Sciences of the United States of America, 2004, 101 (19), pp.7375-80. ⟨10.1073/pnas.0305586101⟩
Article dans une revue hal-00023270v1

The immunoglobulin heavy-chain locus hs3b and hs4 3' enhancers are dispensable for VDJ assembly and somatic hypermutation.

Caroline Le Morvan , Eric Pinaud , Catherine Decourt , Armelle Cuvillier , Michel Cogné
Blood, 2003, 102 (4), pp.1421-7. ⟨10.1182/blood-2002-12-3827⟩
Article dans une revue hal-00023823v1

Germ-line transcription occurs on both the functional and the non-functional alleles of immunoglobulin constant heavy chain genes.

Laurent Delpy , Marc Le Bert , Michel Cogné , Ahmed Amine Khamlichi
European Journal of Immunology, 2003, 33 (8), pp.2108-13. ⟨10.1002/eji.200323969⟩
Article dans une revue hal-00023385v1

Analysis of three genetic markers in IgA nephropathy patients from a single region.

Mireille Drouet , V. Aupetit , Yves Denizot , M. Bois , Franck Bridoux
Clinical Nephrology, 2002, 57 (4), pp.253-60. ⟨10.5414/cnp57253⟩
Article dans une revue hal-00023535v1

B cell development arrest upon insertion of a neo gene between JH and Emu: promoter competition results in transcriptional silencing of germline JH and complete VDJ rearrangements.

Laurent Delpy , Catherine Decourt , Marc Le Bert , Michel Cogné
Journal of Immunology, 2002, 169 (12), pp.6875-82
Article dans une revue hal-00023696v1