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Michel Cogné

178
Documents

Présentation

Domaines de recherche


Compétences

Immunologie Génétique

Publications

NGFR regulates stromal cell activation in germinal centers

Alberto Hernández-Barranco , Vanesa Santos , Marina S Mazariegos , Eduardo Caleiras , Laura Nogués
Cell Reports, 2024, Cell Reports, 43 (2), pp.113705. ⟨10.1016/j.celrep.2024.113705⟩
Article dans une revue hal-04444626v1

Unique repetitive nucleic acid structures mirror switch regions in the human IgH locus

Ophelie Deze , Delfina Ordanoska , Delphine Rossille , Emma Miglierina , Brice Laffleur
Biochimie, 2023, 214, pp.167-175. ⟨10.1016/j.biochi.2023.08.017⟩
Article dans une revue hal-04212710v1
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Demultiplexing Ig repertoires by parallel mRNA/DNA sequencing shows major differential alterations in severe COVID-19

Virginie Pascal , Marine Dupont , Paco de Rouault , David Rizzo , Delphine Rossille
iScience, 2023, 26 (3), pp.106260. ⟨10.1016/j.isci.2023.106260⟩
Article dans une revue inserm-04041493v1
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Attempts to evaluate locus suicide recombination and its potential role in B cell negative selection in the mouse

Nicolas Denis-Lagache , Christelle Oblet , Tiffany Marchiol , Audrey Baylet , Ophélie Teteau
Frontiers in Immunology, 2023, 14, pp.1155906. ⟨10.3389/fimmu.2023.1155906⟩
Article dans une revue hal-04167864v1
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Roles of G4-DNA and G4-RNA in Class Switch Recombination and Additional Regulations in B-Lymphocytes

Ophelie Deze , Brice Laffleur , Michel Cogné
Molecules, 2023, 28 (3), ⟨10.3390/molecules28031159⟩
Article dans une revue hal-04059303v1
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Du self-control lymphocytaire B aux abords thérapeutiques, quelles voies « B-intrinsèques » pour tempérer les réponses et la mémoire IgE ?

Michel Cogné , Z. Dalloul , O. Dézé , M. Le Goff , S. Thomas
Revue francaise d'allergologie, 2022, 62 (5), pp.482-491. ⟨10.1016/j.reval.2021.10.012⟩
Article dans une revue hal-03520779v1
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Editorial: Germinal Centers in Lymphoid and Non-Lymphoid Tissues: Adaptive and Evolving Structures

Michel Cogné , Thierry Fest , Said Aoufouchi
Frontiers in Immunology, 2022, 13, ⟨10.3389/fimmu.2022.880733⟩
Article dans une revue hal-03798529v1
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Beneficial effects of citrulline enteral administration on sepsis-induced T cell mitochondrial dysfunction

Florian Reizine , Murielle Grégoire , Mathieu Lesouhaitier , Valentin Coirier , Juliette Gauthier
Proceedings of the National Academy of Sciences of the United States of America, 2022, 119 (8), pp.e2115139119. ⟨10.1073/pnas.2115139119⟩
Article dans une revue hal-03594344v1
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RNA-based immunoglobulin repertoire sequencing is a new tool for the management of monoclonal gammopathy of renal (kidney) significance

Vincent Javaugue , Virginie Pascal , Sébastien Bender , Sarah Nasraddine , Mathilde Dargelos
Kidney International, 2022, 101 (2), pp.331-337. ⟨10.1016/j.kint.2021.10.017⟩
Article dans une revue hal-03482172v1
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Targeting IgE polyadenylation signal with antisense oligonucleotides decreases IgE secretion and plasma cell viability

Anne Marchalot , Catherine Horiot , Jean-Marie Lambert , Claire Carrion , Christelle Oblet
Journal of Allergy and Clinical Immunology, 2022, 149 (5), pp.1795-1801. ⟨10.1016/j.jaci.2021.09.039⟩
Article dans une revue hal-03482143v1

Neutralizing antibodies against SARS-CoV-2 variants following mRNA booster vaccination in adults older than 65 years

Christine Durier , Laetitia Ninove , Maeva Lefebvre , Anne Radenne , Corinne Desaint
Scientific Reports, 2022, 12 (1), pp.20373. ⟨10.1038/s41598-022-24409-w⟩
Article dans une revue hal-04119081v1
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Distinct B-Cell Specific Transcriptional Contexts of the BCL2 Oncogene Impact Pre-Malignant Development in Mouse Models

Lina Zawil , Tiffany Marchiol , Baptiste Brauge , Alexis Saintamand , Claire Carrion
Cancers, 2022, 14 (21), pp.5337. ⟨10.3390/cancers14215337⟩
Article dans une revue hal-03888678v1

Transcription/Replication Conflicts in Tumorigenesis and Their Potential Role as Novel Therapeutic Targets in Multiple Myeloma

Laure Dutrieux , Yea-Lih Lin , Malik Lutzmann , Raphaël Rodriguez , Michel Cogné
Cancers, 2021, 13 (15), pp.3755. ⟨10.3390/cancers13153755⟩
Article dans une revue hal-04094386v1

Fam72a enforces error-prone DNA repair during antibody diversification

Mélanie Rogier , Jacques Moritz , Isabelle Robert , Chloé Lescale , Vincent Heyer
Nature, 2021, 600 (7888), pp.329-333. ⟨10.1038/s41586-021-04093-y⟩
Article dans une revue hal-03451745v1
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Comparative immune profiling of acute respiratory distress syndrome patients with or without SARS-CoV2 infection

Mikaël Roussel , J. Ferrant , F. Reizine , S. Le Gallou , J. Dulong
Cell Reports Medicine, 2021, 2 (6), pp.100291. ⟨10.1016/j.xcrm.2021.100291⟩
Article dans une revue hal-03229515v1
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Immunotherapy perspectives in the new era of B-cell editing

Natsuko Ueda , Marine Cahen , Yannic Danger , Jérôme Moreaux , Christophe Sirac
Blood Advances, 2021, 5 (6), pp.1770-1779. ⟨10.1182/bloodadvances.2020003792⟩
Article dans une revue hal-03202338v1
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Venoarterial extracorporeal membrane oxygenation induces early immune alterations

Aurelien Frerou , Mathieu Lesouhaitier , Murielle Gregoire , Fabrice Uhel , Arnaud Gacouin
Critical Care, 2021, 25 (1), pp.9. ⟨10.1186/s13054-020-03444-x⟩
Article dans une revue hal-03134918v1
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IgH 3’ regulatory region increases ectopic class switch recombination

Sandrine Le Noir , Amélie Bonaud , Bastien Hervé , Audrey Baylet , François Boyer
PLoS Genetics, 2021, 17 (2), pp.e1009288. ⟨10.1371/journal.pgen.1009288⟩
Article dans une revue hal-03371044v1
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Homéostasie de la réponse IgA et microbiote

Virginie Pascal , Margaux Hiblot , Batoul Wehbi , Jean-Claude Aldigier , Michel Cogné
Médecine/Sciences, 2021, 37 (1), pp.35-40. ⟨10.1051/medsci/2020258⟩
Article dans une revue hal-03120839v1
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Bromodomain and extraterminal (BET) protein inhibition of IgG/IgE production in murine B cells is counter-balanced by a strong Th2 bias

Zeinab Dalloul , Marie Best , Pauline Chenuet , Iman Dalloul , Sandrine Le Noir
Clinical and Translational Immunology, 2021, 10 (6), pp.e1280. ⟨10.1002/cti2.1280⟩
Article dans une revue hal-03283657v1
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Transcription/Replication Conflicts in Tumorigenesis and Their Potential Role as Novel Therapeutic Targets in Multiple Myeloma

Laure Dutrieux , Yea-Lih Lin , Malik Lutzmann , Raphaël Rodriguez , Michel Cogné
Cancers, 2021, 13 (15), pp.3755. ⟨10.3390/cancers13153755⟩
Article dans une revue hal-03365519v1
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Impact of HIV-1 Vpr manipulation of the DNA repair enzyme UNG2 on B lymphocyte class switch recombination

Patrick Eldin , Sophie Péron , Anastasia Galashevskaya , Nicolas Denis-Lagache , Michel Cogné
Journal of Translational Medicine, 2020, 18 (1), ⟨10.1186/s12967-020-02478-7⟩
Article dans une revue hal-02914967v1

Mesangial Deposition Can Strongly Involve Innate-Like IgA Molecules Lacking Affinity Maturation

Batoul Wehbi , Christelle Oblet , François Boyer , Arnaud Huard , Anne Druilhe
Journal of the American Society of Nephrology, 2019, 30 (7), pp.1238-1249. ⟨10.1681/ASN.2018111089⟩
Article dans une revue hal-02361794v1
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Locus suicide recombination actively occurs on the functionally rearranged IgH allele in B- cells from inflamed human lymphoid tissues

Iman Dalloul , François Boyer , Zeinab Dalloul , Amandine Pignarre , Gersende Caron
PLoS ONE, 2019, 15 (6), pp.e1007721. ⟨10.1371/journal.pgen.1007721⟩
Article dans une revue inserm-02273760v1

IgH locus suicide recombination does not depend on NHEJ in contrast to CSR in B cells

Nour Ghazzaui , Hussein Issaoui , Ophélie Alyssa Martin , Alexis Saintamand , Yves Denizot
Cellular and molecular immunology, 2019, 16 (2), pp.201-202. ⟨10.1038/s41423-018-0172-2⟩
Article dans une revue hal-02343984v1
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An Engineered Human Fc Domain that Behaves like a pH-Toggle Switch for Ultra-Long Circulation Persistence

Tae Hyun Kang , Chang-Han Lee , Tae Hyun Kang , Ophélie Godon , Makiko Watanabe
Nature Communications, 2019, 10 (1), pp.5031. ⟨10.1038/s41467-019-13108-2⟩
Article dans une revue pasteur-02448624v1

G-quadruplex DNA targeting alters class-switch recombination in B cells and attenuates allergic inflammation

Zeinab Dalloul , Pauline Chenuet , Iman Dalloul , François Boyer , Jean-Claude Aldigier
Journal of Allergy and Clinical Immunology, 2018, 142 (4), pp.1352-1355. ⟨10.1016/j.jaci.2018.06.011⟩
Article dans une revue hal-02343989v1

Detecting Rare AID-Induced Mutations in B-Lineage Oncogenes from High-Throughput Sequencing Data Using the Detection of Minor Variants by Error Correction Method

Ophélie Alyssa Martin , Armand Garot , Sandrine Le Noir , Jean-Claude Aldigier , Michel Cogné
Journal of Immunology, 2018, 201 (3), pp.950-956. ⟨10.4049/jimmunol.1800203⟩
Article dans une revue hal-02344000v1

Physiological and druggable skipping of immunoglobulin variable exons in plasma cells

Mohamad Omar Ashi , Nivine Srour , Jean-Marie Lambert , Anne Marchalot , Ophélie Martin
Cellular and molecular immunology, 2018, ⟨10.1038/s41423-018-0160-6⟩
Article dans une revue hal-02048156v1

PAX5A and PAX5B isoforms are both efficient to drive B cell differentiation

Charlotte Cresson , Sophie Péron , Laura Jamrog , Nelly Rouquié , Nais Prade
Oncotarget, 2018, 9 (67), ⟨10.18632/oncotarget.26003⟩
Article dans une revue hal-02343994v1
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PAX5A and PAX5B isoforms are both efficient to drive B cell differentiation

Charlotte Cresson , Sophie Péron , Laura Jamrog , Nelly Rouquié , Nais Prade
Oncotarget, 2018, 9 (67), pp.32841-32854. ⟨10.18632/oncotarget.26003⟩
Article dans une revue hal-02566158v1

Mediator contributes to IgH locus VDJ rearrangements by promoting usage of most distal V segments

Iman Dalloul , Zeinab Dalloul , Sandrine Le Noir , François Boyer , Bernardo Reina-San-Martin
Cellular and molecular immunology, 2018, ⟨10.1038/s41423-018-0175-z⟩
Article dans une revue hal-02343957v1

Comprehensive molecular characterization of a heavy chain deposition disease case

Sébastien Bender , Maria Victoria Ayala , Vincent Javaugue , Amélie Bonaud , Michel Cogné
Haematologica, 2018, 103 (11), pp.e557-e560. ⟨10.3324/haematol.2018.196113⟩
Article dans une revue hal-02343962v1

Animal models of monoclonal immunoglobulin-related renal diseases

Christophe Sirac , Guillermo Herrera , Paul Sanders , Vecihi Batuman , Sébastien Bender
Nature Reviews Nephrology, 2018, 14 (4), pp.246-264. ⟨10.1038/nrneph.2018.8⟩
Article dans une revue hal-02344013v1
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Eμ and 3'RR IgH enhancers show hierarchic unilateral dependence in mature B-cells

Alexis Saintamand , Christelle Vincent-Fabert , Marie Marquet , Nour Ghazzaui , Virginie Magnone
Scientific Reports, 2017, 7 (1), pp.442. ⟨10.1038/s41598-017-00575-0⟩
Article dans une revue hal-01517051v1
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Characterization of human FCRL4-positive B cells

Michel Jourdan , Nicolas Robert , Maïlys Cren , Coraline Thibaut , Christophe Duperray
PLoS ONE, 2017, 12 (6), pp.e0179793. ⟨10.1371/journal.pone.0179793⟩
Article dans une revue hal-01560458v1

Unravelling the immunopathological mechanisms of heavy chain deposition disease with implications for clinical management

Frank Bridoux , Vincent Javaugue , Sébastien Bender , Fannie Leroy , Pierre Aucouturier
Kidney International, 2017, 91 (2), pp.423-434. ⟨10.1016/j.kint.2016.09.004⟩
Article dans une revue hal-02364147v1
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The contribution of virtual reality to the diagnosis of spatial navigation disorders and to the study of the role of navigational aids: A systematic literature review.

Michel Cogné , Mathieu Taillade , Bernard N'Kaoua , Annabelle Tarruella , Evelyne Klinger
Annals of Physical and Rehabilitation Medicine, 2016, ⟨10.1016/j.rehab.2015.12.004⟩
Article dans une revue hal-01354011v1

IgA Structure Variations Associate with Immune Stimulations and IgA Mesangial Deposition

Zéliha Oruc , Christelle Oblet , Ahmed Boumédiène , Anne Druilhe , Virginie Pascal
Journal of the American Society of Nephrology, 2016, 27 (9), pp.2748-2761. ⟨10.1681/ASN.2015080911⟩
Article dans une revue hal-01269915v1

Sequential activation and distinct functions for distal and proximal modules within the IgH 3′ regulatory region

Armand Garot , Marie Marquet , Alexis Saintamand , Sébastien Bender , Sandrine Le Noir
Proceedings of the National Academy of Sciences of the United States of America, 2016, 113 (6), pp.1618-1623. ⟨10.1073/pnas.1514090113⟩
Article dans une revue hal-02364206v1
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Deciphering the importance of the palindromic architecture of the immunoglobulin heavy-chain 3’ regulatory region

Alexis Saintamand , Christelle Vincent-Fabert , Armand Garot , Pauline Rouaud , Zéliha Oruc
Nature Communications, 2016, 7, pp.10730. ⟨10.1038/ncomms10730⟩
Article dans une revue hal-01442466v1

First Membrane Proximal External Region-Specific Anti-HIV1 Broadly Neutralizing Monoclonal IgA1 Presenting Short CDRH3 and Low Somatic Mutations.

Fahd Benjelloun , Zéliha Oruc , Nicole M. Thielens , Bernard Verrier , Gael Champier
Journal of Immunology, 2016, 197 (5), pp.1979-88. ⟨10.4049/jimmunol.1600309⟩
Article dans une revue hal-01356638v1
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A plasma cell differentiation quality control ablates B cell clones with biallelic Ig rearrangements and truncated Ig production

Nivine Srour , Guillaume Chemin , Aurélien Tinguely , Mohamad Omar Ashi , Zéliha Oruc
Journal of Experimental Medicine, 2016, 213 (1), pp.109-122. ⟨10.1084/jem.20131511⟩
Article dans une revue hal-01501807v1

Loss of the HVEM Tumor Suppressor in Lymphoma and Restoration by Modified CAR-T Cells

Michael Boice , Darin Salloum , Frédéric Mourcin , Viraj Sanghvi , Rada Amin
Cell, 2016, 167 (2), pp.405-418 e13. ⟨10.1016/j.cell.2016.08.032⟩
Article dans une revue hal-01405853v1

Impaired Lysosomal Function Underlies Monoclonal Light Chain–Associated Renal Fanconi Syndrome

Alessandro Luciani , Christophe Sirac , Sara Terryn , Vincent Javaugue , Jenny Ann Prange
Journal of the American Society of Nephrology, 2016, 27 (7), pp.2049-2061. ⟨10.1681/ASN.2015050581⟩
Article dans une revue hal-02364437v1

Quand les gènes codant les anticorps s’adjoignent des fragments venus d’autres chromosomes

Brice Laffleur , Zeinab Dalloul , Iman Dalloul , Sandrine Le Noir , Michel Cogné
Médecine/Sciences, 2016, 32 (8-9), pp.677-680. ⟨10.1051/medsci/20163208006⟩
Article dans une revue hal-02364198v1

Efficient AID targeting of switch regions is not sufficient for optimal class switch recombination.

Amélie Bonaud , Fabien Lechouane , S Le Noir , O Monestier , Michel Cogné
Nature Communications, 2015
Article dans une revue hal-01212525v1

The IgH 3' regulatory region governs μ chain transcription in mature B lymphocytes and the B cell fate.

Alexis Saintamand , Pauline Rouaud , Armand Garot , Faten Saad , Claire Carrion
Oncotarget, 2015
Article dans une revue hal-01212314v1

Elucidation of IgH 3' region regulatory role during class switch recombination via germline deletion.

Alexis Saintamand , Pauline Rouaud , Faten Saad , G Rios , Michel Cogné
Nature Communications, 2015
Article dans une revue hal-01212563v1
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Developmental Switch in the Transcriptional Activity of a Long-Range Regulatory Element

Fatima-Zohra Braikia , Caroline Conte , Mohamed Moutahir , Yves Denizot , Michel Cogné
Molecular and Cellular Biology, 2015, 35 (19), pp.3370-3380. ⟨10.1128/mcb.00509-15⟩
Article dans une revue hal-01501824v1
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Self-Restrained B Cells Arise following Membrane IgE Expression

Brice Laffleur , Sophie Duchez , Karin Tarte , Nicolas Denis-Lagache , Sophie Péron
Cell Reports, 2015, 10 (6), pp.900-909. ⟨10.1016/j.celrep.2015.01.023⟩
Article dans une revue hal-01116949v1

Comment on "IgH chain class switch recombination: mechanism and regulation".

Alexis Saintamand , Jc Lecron , Frédéric Morel , Michel Cogné , Yves Denizot
Journal of Immunology, 2015
Article dans une revue hal-01212327v1

Self-control for IgE production.

Brice Laffleur , Michel Cogné
Oncotarget, 2015
Article dans une revue hal-01212546v1

A mouse model recapitulating human monoclonal heavy chain deposition disease evidences the relevance of proteasome inhibitor therapy.

Amélie Bonaud , Sébastien Bender , G Touchard , C Lacombe , Nivine Srour
Blood, 2015
Article dans une revue hal-01212560v1

The Eμ enhancer region influences H chain expression and B cell fate without impacting IgVH repertoire and immune response in vivo.

Marie Marquet , Armand Garot , Sébastien Bender , Claire Carrion , Pauline Rouaud
Journal of Immunology, 2014, 193 (3), pp.1171-83. ⟨10.4049/jimmunol.1302868⟩
Article dans une revue hal-01110453v1

Caractéristiques des IgA promptes à se déposer dans le mésangium

J.C. Aldigier , Zéliha Oruc , Christelle Oblet , Ahmed Boumédiène , Alexis Cuvillier
Néphrologie & Thérapeutique, 2014, 10 (5), pp.282. ⟨10.1016/j.nephro.2014.07.354⟩
Article dans une revue hal-01117015v1

Immunoglobulin genes undergo legitimate repair in human B cells not only after cis- but also frequent trans-class switch recombination.

Brice Laffleur , Sylvia M. Bardet , Armand Garot , M Brousse , A Baylet
Genes and Immunity, 2014, 15 (5), pp.341-6. ⟨10.1038/gene.2014.25⟩
Article dans une revue hal-01112042v1
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The class-specific BCR tonic signal modulates lymphomagenesis in a c-myc deregulation transgenic model.

Rada Amin , Abdelghafour Marfak , Céline Pangault , Christelle Oblet , Aurélie Chanut
Oncotarget, 2014, 5 (19), pp.8995-9006. ⟨10.18632/oncotarget.2297⟩
Article dans une revue hal-01067143v1

Elucidation of the enigmatic IgD class-switch recombination via germline deletion of the IgH 3' regulatory region

Pauline Rouaud , Alexis Saintamand , Faten Saad , Claire Carrion , Sandrine Lecardeur
Journal of Experimental Medicine, 2014
Article dans une revue hal-01212566v1

The IgH 3' regulatory region controls somatic hypermutation in germinal center B cells.

Pauline Rouaud , Christelle Vincent-Fabert , Alexis Saintamand , Rémi Fiancette , Marie Marquet
Journal of Experimental Medicine, 2013, 210 (8), pp.1501-7. ⟨10.1084/jem.20130072⟩
Article dans une revue hal-00903790v1

Abnormal apical-to-basal transport of dietary ovalbumin by secretory IgA stimulates a mucosal Th1 response.

J. Abed , C. Lebreton , G. Champier , Alexis Cuvillier , Michel Cogné
Mucosal Immunology, 2013, epub ahead of print. ⟨10.1038/mi.2013.49⟩
Article dans une revue hal-00903792v1

Flexible long-range loops in the VH gene region of the Igh locus facilitate the generation of a diverse antibody repertoire.

Jasna Medvedovic , Anja Ebert , Hiromi Tagoh , Ido M Tamir , Tanja A Schwickert
Immunity, 2013, 39 (2), pp.229-44. ⟨10.1016/j.immuni.2013.08.011⟩
Article dans une revue hal-00903793v1

Activation-induced deaminase in B lymphocyte maturation and beyond.

Michel Cogné
Biomed J, 2013, 36 (6), pp.259-68. ⟨10.4103/2319-4170.113191⟩
Article dans une revue hal-00945344v1

IGHV gene features and MYD88 L265P mutation separate the three marginal zone lymphoma entities and Waldenström macroglobulinemia/lymphoplasmacytic lymphomas.

Nathalie Gachard , M. Parrens , Isabelle Soubeyran , Barbara Petit , A. Marfak
Leukemia, 2013, 27 (1), pp.183-9. ⟨10.1038/leu.2012.257⟩
Article dans une revue hal-00779407v1

Class-specific effector functions of therapeutic antibodies.

Virginie Pascal , Brice Laffleur , Michel Cogné
Methods in Molecular Biology, 2012, 901, pp.295-317. ⟨10.1007/978-1-61779-931-0_19⟩
Article dans une revue hal-00779398v1

Cross talk between immunoglobulin heavy-chain transcription and RNA surveillance during B cell development.

Aurélien Tinguely , Guillaume Chemin , Sophie Péron , Christophe Sirac , Stéphane Reynaud
Molecular and Cellular Biology, 2012, 32 (1), pp.107-17. ⟨10.1128/MCB.06138-11⟩
Article dans une revue hal-00696497v1

Mantle cell lymphoma-like lymphomas in c-myc-3'RR/p53+/- mice and c-myc-3'RR/Cdk4R24C mice: differential oncogenic mechanisms but similar cellular origin.

Pauline Rouaud , Rémi Fiancette , Christelle Vincent-Fabert , Virginie Magnone , Michel Cogné
Oncotarget, 2012, 3 (5), pp.586-93
Article dans une revue hal-00779350v1

Anti-CD20 IgA can protect mice against lymphoma development: evaluation of the direct impact of IgA and cytotoxic effector recruitment on CD20 target cells.

Virginie Pascal , Brice Laffleur , Arnaud Debin , Armelle Cuvillier , Marjolein van Egmond
Haematologica, 2012, 97 (11), pp.1686-94. ⟨10.3324/haematol.2011.061408⟩
Article dans une revue hal-00779391v1

AID-Driven Deletion Causes Immunoglobulin Heavy Chain "Locus Suicide Recombination" in B Cells.

Sophie Péron , Brice Laffleur , Nicolas Denis-Lagache , Jeanne Cook-Moreau , Aurélien Tinguely
Science, 2012, epub ahead of print. ⟨10.1126/science.1218692⟩
Article dans une revue hal-00697665v1

B-cell receptor signal strength influences terminal differentiation.

Fabien Lechouane , Amélie Bonaud , Laurent Delpy , Stefano Casola , Zéliha Oruc
European Journal of Immunology, 2012, epub ahead of print. ⟨10.1002/eji.201242912⟩
Article dans une revue hal-00779414v1

Enhancers located in heavy chain regulatory region (hs3a, hs1,2, hs3b, and hs4) are dispensable for diversity of VDJ recombination.

Pauline Rouaud , Christelle Vincent-Fabert , Rémi Fiancette , Michel Cogné , Eric Pinaud
Journal of Biological Chemistry, 2012, 287 (11), pp.8356-60. ⟨10.1074/jbc.M112.341024⟩
Article dans une revue hal-00696502v1
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Transglutaminase is essential for IgA nephropathy development acting through IgA receptors.

Laureline Berthelot , Christina Papista , Thiago T Maciel , Martine Biarnes-Pelicot , Emilie Tissandie
Journal of Experimental Medicine, 2012, 209 (4), pp.793-806. ⟨10.1084/jem.20112005⟩
Article dans une revue hal-00903832v1

[IgH locus suicide recombination, or when B cells surrender!].

Sophie Péron , Brice Laffleur , Nicolas Denis-Lagache , Jeanne Cook-Moreau , Matthieu Filloux
Médecine/Sciences, 2012, 28 (5), pp.551-4. ⟨10.1051/medsci/2012285023⟩
Article dans une revue hal-00779352v1

A defect of the INK4-Cdk4 checkpoint and Myc collaborate in blastoid mantle cell lymphoma-like lymphoma formation in mice.

Christelle Vincent-Fabert , Rémi Fiancette , Pauline Rouaud , Christel Baudet , Véronique Truffinet
American Journal of Pathology, 2012, 180 (4), pp.1688-701. ⟨10.1016/j.ajpath.2012.01.004⟩
Article dans une revue hal-00696495v1

Specific impairment of proximal tubular cell proliferation by a monoclonal κ light chain responsible for Fanconi syndrome.

Chahrazed El Hamel , Jean-Claude Aldigier , Christelle Oblet , Brice Laffleur , Franck Bridoux
Nephrology Dialysis Transplantation, 2012, 27 (12), pp.4368-77. ⟨10.1093/ndt/gfs261⟩
Article dans une revue hal-00779410v1

Deletion of the α immunoglobulin chain membrane-anchoring region reduces but does not abolish IgA secretion.

Rada Amin , Claire Carrion , Catherine Decourt , Eric Pinaud , Michel Cogné
Immunology, 2012, 136 (1), pp.54-63. ⟨10.1111/j.1365-2567.2012.03557.x⟩
Article dans une revue hal-00696503v1

Production of human or humanized antibodies in mice.

Brice Laffleur , Virginie Pascal , Christophe Sirac , Michel Cogné
Methods in Molecular Biology, 2012, 901, pp.149-59. ⟨10.1007/978-1-61779-931-0_9⟩
Article dans une revue hal-00779395v1

Gammopathy with IgA mesangial deposition provides a monoclonal model of IgA nephritogenicity and offers new insights into its molecular mechanisms.

Ahmed Boumédiène , Christelle Oblet , Zéliha Oruc , Sophie Duchez , Willy Morelle
Nephrology Dialysis Transplantation, 2011, 26 (12), pp.3930-7. ⟨10.1093/ndt/gfr131⟩
Article dans une revue hal-00696463v1

Complexes between nuclear factor-κB p65 and signal transducer and activator of transcription 3 are key actors in inducing activation-induced cytidine deaminase expression and immunoglobulin A production in CD40L plus interleukin-10-treated human blood B cells.

S. Lafarge , H. Hamzeh-Cognasse , Y. Richard , B. Pozzetto , Michel Cogné
Clinical and Experimental Immunology, 2011, 166 (2), pp.171-83. ⟨10.1111/j.1365-2249.2011.04465.x⟩
Article dans une revue hal-00697663v1

Polymeric IgA1 controls erythroblast proliferation and accelerates erythropoiesis recovery in anemia.

S. Coulon , M. Dussiot , D. Grapton , Trovati Maciel T. , Huey Mei Wang P.
Nature Medicine, 2011, 17, pp.1456-1465
Article dans une revue hal-00617557v1

Polymeric IgA1 controls erythroblast proliferation and accelerates erythropoiesis recovery in anemia.

Séverine Coulon , Michaël Dussiot , Damien Grapton , Thiago Trovati Maciel , Pamella Huey Mei Wang
Nature Medicine, 2011, 17 (11), pp.1456-65. ⟨10.1038/nm.2462⟩
Article dans une revue hal-00696490v1

Glycotranscriptome study reveals an enzymatic switch modulating glycosaminoglycan synthesis during B cell development and activation.

Sophie Duchez , Virginie Pascal , Nadine Cogné , Chantal Jayat-Vignoles , Raymond Julien
European Journal of Immunology, 2011, 41 (12), epub ahead of print. ⟨10.1002/eji.201140865⟩
Article dans une revue hal-00696483v1

The IgH locus 3' regulatory region: pulling the strings from behind.

Eric Pinaud , Marie Marquet , Rémi Fiancette , Sophie Péron , Christelle Vincent-Fabert
Advances in immunology, 2011, 110, pp.27-70. ⟨10.1016/B978-0-12-387663-8.00002-8⟩
Article dans une revue hal-00696444v1

Strategies to model AL amyloidosis in mice.

Christophe Sirac , Sébastien Bender , Arnaud Jaccard , Franck Bridoux , C. Lacombe
Amyloid: The Journal of Protein Folding Disorders, 2011, 18 (Suppl 1), pp.45-47. ⟨10.3109/13506129.2011.574354016⟩
Article dans une revue hal-00617188v2

A p53 defect sensitizes various stages of B cell development to lymphomagenesis in mice carrying an IgH 3' regulatory region-driven c-myc transgene.

Rémi Fiancette , Pauline Rouaud , Christelle Vincent-Fabert , Brice Laffleur , Virginie Magnone
Journal of Immunology, 2011, 187 (11), pp.5772-82. ⟨10.4049/jimmunol.1102059⟩
Article dans une revue hal-00696493v1

Toward understanding renal Fanconi syndrome: step by step advances through experimental models.

Christophe Sirac , Franck Bridoux , Marie Essig , Olivier Devuyst , Guy Touchard
Contributions to Nephrology, 2011, 169, pp.247-61. ⟨10.1159/000313962⟩
Article dans une revue hal-00696465v1

Similarity of fine specificity of IgA anti-gliadin antibodies between patients with celiac disease and humanized α1KI mice.

Daniel Sánchez , Gaël Champier , Armelle Cuvillier , Michel Cogné , Aneta Pekáriková
Journal of Agricultural and Food Chemistry, 2011, 59 (7), pp.3092-100. ⟨10.1021/jf1044519⟩
Article dans une revue hal-00696473v1

Glycotranscriptome study reveals an enzymatic switch modulating glycosaminoglycan synthesis during B-cell development and activation

Sophie Duchez , Virginie Pascal , Nadine Cogné , Chantal Jayat-Vignoles , Raymond Julien
European Journal of Immunology, 2011, 41 (12), pp.3632-3644. ⟨10.1002/eji.201140865⟩
Article dans une revue hal-01211951v1

Crystal-storing histiocytosis with renal Fanconi syndrome: pathological and molecular characteristics compared with classical myeloma-associated Fanconi syndrome.

Chahrazed El Hamel , Antoine Thierry , Patrick Trouillas , Franck Bridoux , Claire Carrion
Nephrology Dialysis Transplantation, 2010, 25 (9), pp.2982-90. ⟨10.1093/ndt/gfq129⟩
Article dans une revue hal-00514235v1

Premature replacement of {micro} with {alpha} immunoglobulin chains impairs lymphopoiesis and mucosal homing but promotes plasma cell maturation.

Sophie Duchez , Rada Amin , Nadine Cogné , Laurent Delpy , Christophe Sirac
Proceedings of the National Academy of Sciences of the United States of America, 2010, epub ahead of print. ⟨10.1073/pnas.0912393107⟩
Article dans une revue hal-00454129v1

A myeloma translocation-like model associating CCND1 with the immunoglobulin heavy-chain locus 3' enhancers does not promote by itself B-cell malignancies.

Rémi Fiancette , Rada Amin , Véronique Truffinet , Christelle Vincent-Fabert , Nadine Cogné
Leukemia Research, 2010, 34 (8), pp.1043-51. ⟨10.1016/j.leukres.2009.11.017⟩
Article dans une revue hal-00514237v1

In vivo redundant function of the 3' IgH regulatory element HS3b in the mouse.

Anne-Gaëlle Bébin , Claire Carrion , Marie Marquet , Nadine Cogné , Sandrine Lecardeur
Journal of Immunology, 2010, 184 (7), pp.3710-7. ⟨10.4049/jimmunol.0901978⟩
Article dans une revue hal-00514232v1

The IgH 3' regulatory region and its implication in lymphomagenesis.

Christelle Vincent-Fabert , Rémi Fiancette , Michel Cogné , Eric Pinaud , Yves Denizot
European Journal of Immunology, 2010, 40 (12), pp.3306-11. ⟨10.1002/eji.201040778⟩
Article dans une revue hal-00559583v1

Genomic deletion of the whole IgH 3' regulatory region (hs3a, hs1,2, hs3b, hs4) dramatically affects class switch recombination and Ig secretion to all isotypes.

Christelle Vincent-Fabert , Rémi Fiancette , Eric Pinaud , Véronique Truffinet , Nadine Cogné
Blood, 2010, epub ahead of print. ⟨10.1182/blood-2010-01-264689⟩
Article dans une revue hal-00514236v1

Multiple RNA surveillance mechanisms cooperate to reduce the amount of nonfunctional Ig kappa transcripts.

Guillaume Chemin , Aurélien Tinguely , Christophe Sirac , Fabien Lechouane , Sophie Duchez
Journal of Immunology, 2010, 184 (9), pp.5009-17. ⟨10.4049/jimmunol.0902949⟩
Article dans une revue hal-00511941v1

Ig synthesis and class switching do not require the presence of the hs4 enhancer in the 3' IgH regulatory region.

Christelle Vincent-Fabert , Véronique Truffinet , Rémi Fiancette , Nadine Cogné , Michel Cogné
Journal of Immunology, 2009, 182 (11), pp.6926-32. ⟨10.4049/jimmunol.0900214⟩
Article dans une revue hal-00443742v1

Genetic background modulates susceptibility to oncogen-driven proliferation and lymphoma occurrence in mice carrying a deregulated c-myc transgene.

Christelle Vincent-Fabert , Rémi Fiancette , Véronique Truffinet , Nadine Cogné , Michel Cogné
Leukemia Research, 2009, 33 (11), pp.e203-6. ⟨10.1016/j.leukres.2009.05.018⟩
Article dans une revue hal-00514240v1

Long-range oncogenic activation of Igh-c-myc translocations by the Igh 3' regulatory region.

Monica Gostissa , Catherine T Yan , Julia M Bianco , Michel Cogné , Eric Pinaud
Nature, 2009, 462 (7274), pp.803-7. ⟨10.1038/nature08633⟩
Article dans une revue hal-00443754v1

Uncoupling between Ig somatic hypermutation and oncogene mutation in mouse lymphoma.

Christelle Vincent-Fabert , Véronique Truffinet , Rémi Fiancette , Barbara Petit , Nadine Cogné
Biochimica et Biophysica Acta - Molecular Cell Research, 2009, 1793 (2), pp.418-26. ⟨10.1016/j.bbamcr.2008.10.011⟩
Article dans une revue hal-00363954v1
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Transgenesis and humanization of murine antibodies.

Michel Cogné , Sophie Duchez , Virginie Pascal
Médecine/Sciences, 2009, 25 (12), pp.1149-54
Article dans une revue hal-00443792v1

[Physiopathology of bullous pemphigoid]

V. Doffoel-Hantz , Michel Cogné , M. Drouet , Agnès Sparsa , J.-M. Bonnetblanc
Annales de Dermatologie et de Vénéréologie, 2009, 136 (10), pp.740-7; quiz 739, 748. ⟨10.1016/j.annder.2008.10.044⟩
Article dans une revue hal-00452834v1

Splenic marginal zone lymphomas and lymphoplasmacytic lymphomas originate from B-cell compartments with two different antigen-exposure histories.

M. Parrens , Nathalie Gachard , Barbara Petit , A. Marfak , E. Troadec
Leukemia, 2008, 22 (8), pp.1621-4. ⟨10.1038/leu.2008.24⟩
Article dans une revue hal-00364488v1

[Physiopathology of herpetiform dermatitis. Current data]

V. Doffoel-Hantz , Michel Cogné , Agnès Sparsa , J.-M. Bonnetblanc , Mireille Drouet
Annales de Dermatologie et de Vénéréologie, 2008, 135 (11), pp.784-8; quiz 783. ⟨10.1016/j.annder.2008.02.030⟩
Article dans une revue hal-00363969v1

The 3' IgH locus control region is sufficient to deregulate a c-myc transgene and promote mature B cell malignancies with a predominant Burkitt-like phenotype.

Véronique Truffinet , Eric Pinaud , Nadine Cogné , Barbara Petit , Laurence Guglielmi
Journal of Immunology, 2007, 179 (9), pp.6033-6042
Article dans une revue hal-00181178v1

Use of both CD63 up regulation and IgE down regulation for the flow cytometric analysis of allergen induced basophil activation. Definition of an activation index.

Jean Sainte-Laudy , Ahmed Boumédiène , F. Touraine , Isabelle Orsel , C. Brianchon
Inflammation Research, 2007, 56 (7), pp.291-6. ⟨10.1007/s00011-007-7014-5⟩
Article dans une revue hal-00166018v1

Clinico-biological characteristics of flow cytometry applied to hypersensitivity to NSAIDs.

J. Sainte-Laudy , F. Touraine , Ahmed Boumédiène , F. Bonnaud , Michel Cogné
Inflammation Research, 2007, 56 Suppl 1, pp.S63-4
Article dans une revue hal-00452811v1

High-dose melphalan versus melphalan plus dexamethasone for AL amyloidosis.

Arnaud Jaccard , Philippe Moreau , Véronique Leblond , Xavier Leleu , Lofti Benboubker
New England Journal of Medicine, 2007, 357 (11), pp.1083-93
Article dans une revue hal-00172895v1

S-S synapsis during class switch recombination is promoted by distantly located transcriptional elements and activation-induced deaminase.

Robert Wuerffel , Lili Wang , Fernando Grigera , John Manis , Erik Selsing
Immunity, 2007, 27 (5), pp.711-22. ⟨10.1016/j.immuni.2007.09.007⟩
Article dans une revue hal-00363968v1

Platelet activation after aortic prosthetic valve surgery.

Alexandre Leguyader , Reina Watanabe , Julien Berbé , Ahmed Boumédiène , Michel Cogné
Interactive Cardiovascular and Thoracic Surgery, 2006, 5 (1), pp.60-4. ⟨10.1510/icvts.2005.115733⟩
Article dans une revue hal-00452815v1

Analysis of IgE down regulation induced by basophil activation. Application to the diagnosis of muscle relaxant allergic hypersensitivity by flow cytometry.

J. Sainte-Laudy , Ahmed Boumédiène , F. Touraine , I. Orsel , Michel Cogné
Inflammation Research, 2006, 55 Suppl 1, pp.S21-2. ⟨10.1007/s00011-005-0023-3⟩
Article dans une revue hal-00452816v1

Germ line transcription in mice bearing neor gene downstream of Igamma3 exon in the Ig heavy chain locus.

Maha Samara , Zéliha Oruc , Hei-Lanne Dougier , Tawer Essawi , Michel Cogné
International Immunology, 2006, 18 (4), pp.581-589. ⟨10.1093/intimm/dxh400⟩
Article dans une revue hal-00021571v1

Interallelic class switch recombination can reverse allelic exclusion and allow trans-complementation of an IgH locus switching defect.

Hei-Lanne Dougier , Stéphane Reynaud , Eric Pinaud , Claire Carrion , Laurent Delpy
European Journal of Immunology, 2006, 36 (8), pp.2181-91. ⟨10.1002/eji.200535529⟩
Article dans une revue hal-00088115v1

Polyclonal IgG4 hypergammaglobulinemia associated with plasmacytic lymphadenopathy, anemia and nephropathy.

Emmanuelle Boulanger , Vincent Fuentes , Véronique Meignin , Béatrice Mougenot , Sylvaine Labaume
Annals of Hematology, 2006, 85 (12), pp.833-40. ⟨10.1007/s00277-006-0158-5⟩
Article dans une revue hal-00451895v1

Light chain inclusion permits terminal B cell differentiation and does not necessarily result in autoreactivity.

Christophe Sirac , Claire Carrion , Sophie Duchez , Isabelle Comte , Michel Cogné
Proceedings of the National Academy of Sciences of the United States of America, 2006, 103 (20), pp.7747-52. ⟨10.1073/pnas.0509121103⟩
Article dans une revue hal-00073857v1

Role of the monoclonal kappa chain V domain and reversibility of renal damage in a transgenic model of acquired Fanconi syndrome.

Christophe Sirac , Franck Bridoux , Claire Carrion , Olivier Devuyst , Béatrice Fernandez
Blood, 2006, 108 (2), pp.536-543. ⟨10.1182/blood-2005-11-4419⟩
Article dans une revue hal-00085051v1
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The 5′HS4 insulator element is an efficient tool to analyse the transient expression of an Eμ-GFP vector in a transgenic mouse model

Laurence Guglielmi , Véronique Truffinet , Claire Carrion , Marc Le Bert , Nadine Cogné
Transgenic Research, 2005, 14(4), pp.361-364. ⟨10.1007/s11248-005-3239-7⟩
Article dans une revue hal-00023265v1

Indolent lymphoplasmacytic and marginal zone B-cell lymphomas: absence of both IRF4 and Ki67 expression identifies a better prognosis subgroup.

Barbara Petit , Mp Chaury , Arnaud Jaccard , Nathalie Gachard , S. Moalic-Judge
Haematologica, 2005, 90(2), pp.200-6
Article dans une revue hal-00022403v1

Interallelic class switch recombination contributes significantly to class switching in mouse B cells.

Stéphane Reynaud , Laurent Delpy , Laurence Fleury , Hei-Lanne Dougier , Christophe Sirac
Journal of Immunology, 2005, 174 (10), pp.6176-83
Article dans une revue hal-00458866v1

The chicken β-globin HS4 insulator is not a silver bullet to obtain copy-number dependent expression of transgenes in stable B cell transfectants

Véronique Truffinet , Laurence Guglielmi , Michel Cogné , Yves Denizot
Immunology Letters, 2005, 96(2), pp.303-4. ⟨10.1016/j.imlet.2004.09.002⟩
Article dans une revue hal-00022648v1

Interallelic Class Switch Recombination Contributes Significantly to Class Switching in Mouse B Cells

Stéphane Reynaud , Laurent Delpy , Laurence Fleury , Hei-Lanne Dougier , Christophe Sirac
Journal of Immunology, 2005, 174, pp.5905-5906
Article dans une revue hal-00022865v1

Fanconi's syndrome induced by a monoclonal Vkappa3 light chain in Waldenstrom's macroglobulinemia.

Franck Bridoux , Christophe Sirac , V. Hugue , Catherine Decourt , A. Thierry
American Journal of Kidney Diseases, 2005, 45 (4), pp.749-57. ⟨10.1053/j.ajkd.2004.12.020⟩
Article dans une revue hal-00022808v1

Immunoglobulin class-switch recombination in mice devoid of any S mu tandem repeat.

Ahmed Amine Khamlichi , Florence Glaudet , Zéliha Oruc , Vincent Denis , Marc Le Bert
Blood, 2004, 103 (10), pp.3828-36. ⟨10.1182/blood-2003-10-3470⟩
Article dans une revue hal-00023269v1

Immunologic basis for the rare occurrence of true nonsecretory plasma cell dyscrasias.

Catherine Decourt , Horia Radu Galea , Christophe Sirac , Michel Cogné
Journal of Leukocyte Biology, 2004, 76 (3), pp.528-36. ⟨10.1189/jlb.0803382⟩
Article dans une revue hal-00023271v1

Induction of somatic hypermutation by antigen-specific B cell receptors in the human BL2 cell line.

Florence Glaudet , Vincent Denis , Michel Cogné , Ahmed Amine Khamlichi
European Journal of Immunology, 2004, 34 (6), pp.1637-45. ⟨10.1002/eji.200324741⟩
Article dans une revue hal-00023350v1

The polymorphism of the locus control region lying downstream the human IgH locus is restricted to hs1,2 but not to hs3 and hs4 enhancers.

Laurence Guglielmi , Véronique Truffinet , Emmanuelle Magnoux , Michel Cogné , Yves Denizot
Immunology Letters, 2004, 94 (1-2), pp.77-81. ⟨10.1016/j.imlet.2004.04.003⟩
Article dans une revue hal-00023366v1

RNA surveillance down-regulates expression of nonfunctional kappa alleles and detects premature termination within the last kappa exon.

Laurent Delpy , Christophe Sirac , Emmanuelle Magnoux , Sophie Duchez , Michel Cogné
Proceedings of the National Academy of Sciences of the United States of America, 2004, 101 (19), pp.7375-80. ⟨10.1073/pnas.0305586101⟩
Article dans une revue hal-00023270v1

Transcription-dependent somatic hypermutation occurs at similar levels on functional and nonfunctional rearranged IgH alleles.

Laurent Delpy , Christophe Sirac , Caroline Le Morvan , Michel Cogné
Journal of Immunology, 2004, 173 (3), pp.1842-8
Article dans une revue hal-00023372v1

The immunoglobulin heavy-chain locus hs3b and hs4 3' enhancers are dispensable for VDJ assembly and somatic hypermutation.

Caroline Le Morvan , Eric Pinaud , Catherine Decourt , Armelle Cuvillier , Michel Cogné
Blood, 2003, 102 (4), pp.1421-7. ⟨10.1182/blood-2002-12-3827⟩
Article dans une revue hal-00023823v1

Combination of 3' and 5' IgH regulatory elements mimics the B-specific endogenous expression pattern of IgH genes from pro-B cells to mature B cells in a transgenic mouse model.

Laurence Guglielmi , Marc Le Bert , Isabelle Comte , Marie Laure Dessain , Mireille Drouet
Biochimica et Biophysica Acta - Molecular Cell Research, 2003, 1642 (3), pp.181-90. ⟨10.1016/j.bbamcr.2003.08.005⟩
Article dans une revue hal-00023378v1

Nuclear factors, hs1,2 enhancer and IgA nephropathy.

Barbara Bessette , Laurence Guglielmi , Michel Cogné , Yves Denizot
Kidney International, 2003, 63 (2), pp.767. ⟨10.1046/j.1523-1755.2003.00789.x⟩
Article dans une revue hal-00023525v1

A monoclonal V kappa l light chain responsible for incomplete proximal tubulopathy.

Catherine Decourt , Franck Bridoux , Guy Touchard , Michel Cogné
American Journal of Kidney Diseases, 2003, 41 (2), pp.497-504. ⟨10.1053/ajkd.2003.50062⟩
Article dans une revue hal-00023380v1

Insulators to improve expression of a 3(')IgH LCR-driven reporter gene in transgenic mouse models.

Laurence Guglielmi , Marc Le Bert , Véronique Truffinet , Michel Cogné , Yves Denizot
Biochemical and Biophysical Research Communications, 2003, 307 (3), pp.466-71. ⟨10.1016/S0006-291X(03)01185-9⟩
Article dans une revue hal-00023524v1

Germ-line transcription occurs on both the functional and the non-functional alleles of immunoglobulin constant heavy chain genes.

Laurent Delpy , Marc Le Bert , Michel Cogné , Ahmed Amine Khamlichi
European Journal of Immunology, 2003, 33 (8), pp.2108-13. ⟨10.1002/eji.200323969⟩
Article dans une revue hal-00023385v1

The beta-globin HS4 insulator confers copy-number dependent expression of IgH regulatory elements in stable B cell transfectants.

Laurence Guglielmi , Véronique Truffinet , Michel Cogné , Yves Denizot
Immunology Letters, 2003, 89 (2-3), pp.119-23. ⟨10.1016/S0165-2478(03)00126-3⟩
Article dans une revue hal-00023379v1

Effect of the Eμ IgH enhancer on expression of a GFP reporter gene in transfected B cells and transgenic mice

Laurence Guglielmi , Marc Le Bert , Michel Cogné , Yves Denizot
Immunology Letters, 2003, 86(1), pp.77-83. ⟨10.1016/S0165-2478(02)00264-X⟩
Article dans une revue hal-00023530v1

B cell development arrest upon insertion of a neo gene between JH and Emu: promoter competition results in transcriptional silencing of germline JH and complete VDJ rearrangements.

Laurent Delpy , Catherine Decourt , Marc Le Bert , Michel Cogné
Journal of Immunology, 2002, 169 (12), pp.6875-82
Article dans une revue hal-00023696v1

Implication of paraoxonase-1 polymorphism 192 in Alzheimer’s disease.

Thierry Dantoine , J. Debord , M. Drouet , Louis Merle , Michel Cogné
Annals of the New York Academy of Sciences, 2002
Article dans une revue hal-01335856v1

GM-CSF and IL-12 production by malignant plasma cells promotes cell-mediated immune responses against monoclonal Ig determinants in a light chain myeloma model.

H.R. Galea , Michel Cogné
Clinical and Experimental Immunology, 2002, 129 (2), pp.247-53. ⟨10.1046/j.1365-2249.2002.01929.x⟩
Article dans une revue hal-00023536v1

Implication des facteurs vasculaires dans les troubles cognitifs du sujet âgé : relation entre le polymorphisme 192 de la paraoxonase 1 et la maladie d’Alzheimer.

Thierry Dantoine , M Drouet , J. Debord , H Lacroix , Louis Merle
La Revue de Médecine Interne, 2002
Article dans une revue hal-01338479v1

Molecular study of an IgG1kappa cryoglobulin yielding organized microtubular deposits and glomerulonephritis in the course of chronic lymphocytic leukaemia.

H.R. Galea , Franck Bridoux , Jean-Claude Aldigier , François Paraf , Dominique Bordessoule
Clinical and Experimental Immunology, 2002, 129 (1), pp.113-8. ⟨10.1046/j.1365-2249.2002.01896.x⟩
Article dans une revue hal-00023688v1

Analysis of three genetic markers in IgA nephropathy patients from a single region.

Mireille Drouet , V. Aupetit , Yves Denizot , M. Bois , Franck Bridoux
Clinical Nephrology, 2002, 57 (4), pp.253-60. ⟨10.5414/cnp57253⟩
Article dans une revue hal-00023535v1

Light chain myeloma plasma cells induce a strong cell-mediated immune response mainly directed against the monoclonal light chain determinants in a murine experimental model.

Horia Galea , Yves Denizot , Michel Cogné
Cancer Immunology, Immunotherapy, 2002, 51 (4), pp.229-34. ⟨10.1007/s00262-002-0274-6⟩
Article dans une revue hal-00023825v1

192 and 55 paraoxonase-1 gene polymorphisms and coronary artery disease in Hemodialysis patients.

Thierry Dantoine , Michel Cogné , Jean-Pierre Charmes , Louis Merle , Mireille Drouet
Clinical Journal of the American Society of Nephrology, 2002
Article dans une revue hal-01336537v1

Characterization of the murine gene for subunit VIIaL of cytochrome c oxidase.

K. Chantrel-Groussard , Laurent Delpy , Marie-Hélène Ratinaud , Michel Cogné
Comptes rendus de l’Académie des sciences. Série III, Sciences de la vie, 2001, 324 (12), pp.1117-23
Article dans une revue hal-00458870v1

Localization of the 3′ IgH Locus Elements that Effect Long-Distance Regulation of Class Switch Recombination

Eric Pinaud , Ahmed Amine Khamlichi , Caroline Le Morvan , Mireille Drouet , Valérie Nalesso
Immunity, 2001, 15 (2), pp.187-199. ⟨10.1016/s1074-7613(01)00181-9⟩
Article dans une revue hal-03480612v1
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Heavy-Chain Deposition Disease

Pierre Aucouturier , Ahmed A Khamlichi , Guy Touchard , Eve Justrabo , Michel Cogné
New England Journal of Medicine, 1993, 329 (19), pp.1389 - 1393. ⟨10.1056/NEJM199311043291905⟩
Article dans une revue inserm-01876787v1
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Complementary DNA sequence of human amyloidogenic immunoglobulin light-chain precursors.

Pierre Aucouturier , Ahmed A Khamlichi , Jean-Louis Preud'Homme , Marc Bauwens , Guy Touchard
Biochemical Journal, 1992, 285, pp.149-52. ⟨10.1042/bj2850149⟩
Article dans une revue inserm-01876794v1
Image document

Structure of a monoclonal kappa chain of the V kappa IV subgroup in the kidney and plasma cells in light chain deposition disease.

Michel Cogné , Jean-Louis Preud'Homme , Marc Bauwens , Guy Touchard , Pierre Aucouturier
Journal of Clinical Investigation, 1991, 87 (6), pp.2186 - 2190. ⟨10.1172/JCI115252⟩
Article dans une revue inserm-01876801v1

Integrative Single-Cell RNA-Seq and Single-Cell ATAC-Seq Analysis of Human Plasma Cell Differentiation

Elina Alaterre , Sara Ovejero , Marion Espéli , Thierry Fest , Michel Cogné
65th Annual Meeting of the American-Society-of-Hematology (ASH), Dec 2023, San Diego, United States. ⟨10.1182/blood-2023-181507⟩
Communication dans un congrès hal-04513440v1

A Prospective Phase II Trial of Lenalidomide and Dexamethasone (Len-Dex) in POEMS Syndrome

Arnaud Jaccard , A. Danielou-Lazareth , L. Karlin , S. Choquet , L. Frenzel
15th International Myeloma Workshop, Sep 2015, Rome, Italy. pp.e57, ⟨10.1016/j.clml.2015.07.197⟩
Communication dans un congrès hal-01228183v1

BCR expression and B Cell Fate

Michel Cogné
French Hematology Society 2014 congress, Mar 2014, Paris, France
Communication dans un congrès hal-00949513v1

Control of B cell fate after AID-mediated modulation of BCR expression

Michel Cogné
Symposium "Antibodies: the good, the bad, and the promising, Feb 2014, Amsterdam, Netherlands
Communication dans un congrès hal-00949511v1

B cells switching to deadly paths

Michel Cogné
Henry Kunkel Society's 22nd Annual Meeting, "Human Immunology in Health and Disease, Apr 2014, New-York, United States
Communication dans un congrès hal-00949516v1

Breakthrough of high troughput studies in marginal zone lymphomas and Waldenström macroglobulinemia

Michel Cogné
3rd Workshop Normal and neoplastic B cells, Sep 2013, Oléron, France
Communication dans un congrès hal-00949548v1

Symposium "Allelic gene regulation in health and disease"

Michel Cogné
Fédération de Médecine Translationnelle de Strasbourg" (FMTS), Dec 2013, Strasbourg, France
Communication dans un congrès hal-00949510v1

Modulation of B cell fate upon AID-mediated Ig gene recombination

Michel Cogné
3rd workshop normal and neoplastic B cells, Sep 2013, Oléron, France
Communication dans un congrès hal-00949547v1

Immunoglobulin genes in mature B cells: from biallelic accessibility to monoallelic expression

Michel Cogné
Symposium "Allelic gene regulation in health and disease", Feb 2013, Toulouse, France
Communication dans un congrès hal-00949506v1

Locus suicide recombination in mature B cells

Michel Cogné
Mutations, Malignancy and Memory, Mar 2012, Boston, United States
Communication dans un congrès hal-00697686v1

Locus suicide recombination in mature B cells

Michel Cogné
Keystone meeting "Mutations, Malignancy and Memory, Mar 2012, Boston, United States
Communication dans un congrès hal-00949503v1

In vitro and in vivo evaluation of anti-CD20 antibodies shows the IgA class to surpass IgG for direct effect on target cells.

Michel Cogné
ACCITH Meeting "Antibodies and therapeutic targeting, Sep 2011, Strasbourg, France
Communication dans un congrès hal-00949494v1

Modèles murins d'étude mutationnelle du locus IgH et lymphomogenèse

Michel Cogné
1st French Lymphoma Workshop, Jan 2011, Rennes, France
Communication dans un congrès hal-00697680v1

In vitro and in vivo evaluation of anti-CD20 antibodies shows the IgA class to surpass IgG for direct effect on target cells.

Michel Cogné
Forum "Anticorps et ciblage thérapeutique" du GDR ACCITH, Sep 2011, Strasbourg, France
Communication dans un congrès hal-00697682v1

Modèles murins d'étude mutationnelle du locus IgH et lymphomogenèse

Michel Cogné
1st French Lymphoma Workshop, Rennes, 20-21 janvier 2011, Jan 2011, Rennes, France
Communication dans un congrès hal-00949493v1

Regulation of immunoglobulin expression in mature B cells

Michel Cogné
International meeting on "B cells and Antibodies", Jerusalem, October 23-26, 2011, Oct 2011, Jésuralem, Israel
Communication dans un congrès hal-00949500v1

Regulation of immunoglobulin expression in mature B cells

Michel Cogné
International meeting on "B cells and Antibodies, Oct 2011, Jérusalem, Israel
Communication dans un congrès hal-00697685v1

Régulation et dérégulation: les moteurs génétiques exposant le lymphocyte B à la perte de contrôle

Michel Cogné
21èmes journées de l'Association Nationale des Enseignants de Biologie Cellulaire, Sep 2010, Aubazine, France
Communication dans un congrès hal-00697678v1

Production of IgA antibodies and their variants.

Michel Cogné
9th International Congress on Recombinant Antibodies 2010, Jun 2010, Berlin, Germany
Communication dans un congrès hal-00697674v1

Régulation de l'expression du locus IGH et oncogenèse

Michel Cogné
Congrès 2010 du Club Hématopoièse et oncogenèse (CHO), Sep 2010, Giens, France
Communication dans un congrès hal-00697676v1

Applying Cutting-Edge Antibody Engineering For the Development of New Generation of Humanised Antibodies

Michel Cogné
IQPC meeting on Therapeutic antibodies, Sep 2009, London, United Kingdom
Communication dans un congrès hal-00697672v1

Autologus stern celle transplantation (ASCT) versus oral melphalan and high-dose dexamethasone in patients with AL (primary) amyloisdosis : results of the French multicentric randomized trial (MAG and IFM intergroup).

Arnaud Jaccard , P. Moreau , V. Leblond , X. Leleu , L Bennoubker
Communication orale présentée à 'The American Society of Hematology 47th Annual meeting and Exposition", Dec 2005, Nouvelle Orléans (Louisiane), United States
Communication dans un congrès hal-01135622v1

Démence du sujet âgé et polymorphisme génétique de la paraoxonase 1.

Thierry Dantoine , C Puech , Mireille Drouet , J. Debord , Laurence Bernard-Bourzeix
Société Française de Gériatrie et de Gérontologie, 2002, Limoges, France
Communication dans un congrès hal-01338464v1

Rôle du polymorphisme génétique de la paraoxonase 1 dans la maladie d’Alzheimer.

Thierry Dantoine , Mireille Drouet , J. Debord , Michel Cogné , Louis Merle
VIIème Congrès International Francophone de Gérontologie. Bruxelles, Belgique, 2002, Bruxelles, France
Communication dans un congrès hal-01336564v1

Polymorphisme génétique de la paraoxonase 1 et risque coronarien de l'insuffisant rénal chronique hémodialysé.

C Rebeyrotte , J. Debord , Mireille Drouet , Thierry Dantoine , Jean-Pierre Charmes
Société de Néphrologie, 2000, Tours, France
Communication dans un congrès hal-01337138v1

Atteintes uro-néphrologiques au cours des amyloses

Franck Bridoux , Arnaud Jaccard , Christophe Sirac , J. Gillmore , Michel Cogné
Atteintes uro-néphrologiques au cours des maladies systémiques, Flammarion Médecine Sciences, pp.1-22, 2009
Chapitre d'ouvrage hal-00453323v1

Renal disease in cryoglobulinemic vasculitis

Franck Bridoux , Christophe Sirac , Arnaud Jaccard , R. Abou Ayache , Jm Goujon
The kidney in systemic autoimmune diseases, Elsevier, pp.215-240, 2008
Chapitre d'ouvrage hal-00453329v1