Michel Cogné

182
Documents

Présentation


Compétences

Immunologie Génétique

Publications

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Publications

Image document

NGFR regulates stromal cell activation in germinal centers

Alberto Hernández-Barranco , Vanesa Santos , Marina S Mazariegos , Eduardo Caleiras , Laura Nogués et al.
Cell Reports, 2024, Cell Reports, 43 (2), pp.113705. ⟨10.1016/j.celrep.2024.113705⟩
Article dans une revue hal-04444626 v1
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Single-hit genome editing optimized for maturation in B cells redirects their specificity toward tumor antigens

Natsuko Ueda , Marine Cahen , Jenny Leonard , Laurent Deleurme , Stéphane Dreano et al.
Scientific Reports, 2024, 14 (1), pp.22432. ⟨10.1038/s41598-024-74005-3⟩
Article dans une revue hal-04723581 v1

Neutrophil phenotype, effector functions, and microbicidal activity in patients with SARS-CoV-2-associated ARDS

Quentin Quelven , Murielle Grégoire , Valentin Coirier , Arnaud Gacouin , Simon Le Gallou et al.
Journal of Leukocyte Biology, 2024, 117 (1), pp.qiae195. ⟨10.1093/jleuko/qiae195⟩
Article dans une revue hal-04721254 v1
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Unique repetitive nucleic acid structures mirror switch regions in the human IgH locus

Ophelie Deze , Delfina Ordanoska , Delphine Rossille , Emma Miglierina , Brice Laffleur et al.
Biochimie, 2023, 214, pp.167-175. ⟨10.1016/j.biochi.2023.08.017⟩
Article dans une revue hal-04212710 v1
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Demultiplexing Ig repertoires by parallel mRNA/DNA sequencing shows major differential alterations in severe COVID-19

Virginie Pascal , Marine Dupont , Paco de Rouault , David Rizzo , Delphine Rossille et al.
iScience, 2023, 26 (3), pp.106260. ⟨10.1016/j.isci.2023.106260⟩
Article dans une revue inserm-04041493 v1
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Roles of G4-DNA and G4-RNA in Class Switch Recombination and Additional Regulations in B-Lymphocytes

Ophelie Deze , Brice Laffleur , Michel Cogné
Molecules, 2023, 28 (3), ⟨10.3390/molecules28031159⟩
Article dans une revue hal-04059303 v1
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Attempts to evaluate locus suicide recombination and its potential role in B cell negative selection in the mouse

Nicolas Denis-Lagache , Christelle Oblet , Tiffany Marchiol , Audrey Baylet , Ophélie Teteau et al.
Frontiers in Immunology, 2023, 14, pp.1155906. ⟨10.3389/fimmu.2023.1155906⟩
Article dans une revue hal-04167864 v1
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Targeting IgE polyadenylation signal with antisense oligonucleotides decreases IgE secretion and plasma cell viability

Anne Marchalot , Catherine Horiot , Jean-Marie Lambert , Claire Carrion , Christelle Oblet et al.
Journal of Allergy and Clinical Immunology, 2022, 149 (5), pp.1795-1801. ⟨10.1016/j.jaci.2021.09.039⟩
Article dans une revue hal-03482143 v1
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Neutralizing antibodies against SARS-CoV-2 variants following mRNA booster vaccination in adults older than 65 years

Christine Durier , Laetitia Ninove , Maeva Lefebvre , Anne Radenne , Corinne Desaint et al.
Scientific Reports, 2022, 12 (1), pp.20373. ⟨10.1038/s41598-022-24409-w⟩
Article dans une revue hal-04119081 v1
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RNA-based immunoglobulin repertoire sequencing is a new tool for the management of monoclonal gammopathy of renal (kidney) significance

Vincent Javaugue , Virginie Pascal , Sébastien Bender , Sarah Nasraddine , Mathilde Dargelos et al.
Kidney International, 2022, 101 (2), pp.331-337. ⟨10.1016/j.kint.2021.10.017⟩
Article dans une revue hal-03482172 v1
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Beneficial effects of citrulline enteral administration on sepsis-induced T cell mitochondrial dysfunction

Florian Reizine , Murielle Grégoire , Mathieu Lesouhaitier , Valentin Coirier , Juliette Gauthier et al.
Proceedings of the National Academy of Sciences of the United States of America, 2022, 119 (8), pp.e2115139119. ⟨10.1073/pnas.2115139119⟩
Article dans une revue hal-03594344 v1
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Editorial: Germinal Centers in Lymphoid and Non-Lymphoid Tissues: Adaptive and Evolving Structures

Michel Cogné , Thierry Fest , Said Aoufouchi
Frontiers in Immunology, 2022, 13, pp.880733. ⟨10.3389/fimmu.2022.880733⟩
Article dans une revue hal-03798529 v2
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Du self-control lymphocytaire B aux abords thérapeutiques, quelles voies « B-intrinsèques » pour tempérer les réponses et la mémoire IgE ?

Michel Cogné , Z. Dalloul , O. Dézé , M. Le Goff , S. Thomas et al.
Revue Française d'Allergologie, 2022, 62 (5), pp.482-491. ⟨10.1016/j.reval.2021.10.012⟩
Article dans une revue hal-03520779 v1
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Distinct B-Cell Specific Transcriptional Contexts of the BCL2 Oncogene Impact Pre-Malignant Development in Mouse Models

Lina Zawil , Tiffany Marchiol , Baptiste Brauge , Alexis Saintamand , Claire Carrion et al.
Cancers, 2022, 14 (21), pp.5337. ⟨10.3390/cancers14215337⟩
Article dans une revue hal-03888678 v1
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Bromodomain and extraterminal (BET) protein inhibition of IgG/IgE production in murine B cells is counter-balanced by a strong Th2 bias

Zeinab Dalloul , Marie Best , Pauline Chenuet , Iman Dalloul , Sandrine Le Noir et al.
Clinical and Translational Immunology, 2021, 10 (6), pp.e1280. ⟨10.1002/cti2.1280⟩
Article dans une revue hal-03283657 v1
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Transcription/Replication Conflicts in Tumorigenesis and Their Potential Role as Novel Therapeutic Targets in Multiple Myeloma

Laure Dutrieux , Yea-Lih Lin , Malik Lutzmann , Raphaël Rodriguez , Michel Cogné et al.
Cancers, 2021, 13 (15), pp.3755. ⟨10.3390/cancers13153755⟩
Article dans une revue hal-03365519 v1
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Comparative immune profiling of acute respiratory distress syndrome patients with or without SARS-CoV2 infection

Mikaël Roussel , J. Ferrant , F. Reizine , S. Le Gallou , J. Dulong et al.
Cell Reports Medicine, 2021, 2 (6), pp.100291. ⟨10.1016/j.xcrm.2021.100291⟩
Article dans une revue hal-03229515 v1
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Immunotherapy perspectives in the new era of B-cell editing

Natsuko Ueda , Marine Cahen , Yannic Danger , Jérôme Moreaux , Christophe Sirac et al.
Blood Advances, 2021, 5 (6), pp.1770-1779. ⟨10.1182/bloodadvances.2020003792⟩
Article dans une revue hal-03202338 v1

Fam72a enforces error-prone DNA repair during antibody diversification

Mélanie Rogier , Jacques Moritz , Isabelle Robert , Chloé Lescale , Vincent Heyer et al.
Nature, 2021, 600 (7888), pp.329-333. ⟨10.1038/s41586-021-04093-y⟩
Article dans une revue hal-03451745 v1

Transcription/Replication Conflicts in Tumorigenesis and Their Potential Role as Novel Therapeutic Targets in Multiple Myeloma

Laure Dutrieux , Yea-Lih Lin , Malik Lutzmann , Raphaël Rodriguez , Michel Cogné et al.
Cancers, 2021, 13 (15), pp.3755. ⟨10.3390/cancers13153755⟩
Article dans une revue hal-04094386 v1
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Homéostasie de la réponse IgA et microbiote

Virginie Pascal , Margaux Hiblot , Batoul Wehbi , Jean-Claude Aldigier , Michel Cogné
Médecine/Sciences, 2021, 37 (1), pp.35-40. ⟨10.1051/medsci/2020258⟩
Article dans une revue hal-03120839 v1
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IgH 3’ regulatory region increases ectopic class switch recombination

Sandrine Le Noir , Amélie Bonaud , Bastien Hervé , Audrey Baylet , François Boyer et al.
PLoS Genetics, 2021, 17 (2), pp.e1009288. ⟨10.1371/journal.pgen.1009288⟩
Article dans une revue hal-03371044 v1
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Venoarterial extracorporeal membrane oxygenation induces early immune alterations

Aurelien Frerou , Mathieu Lesouhaitier , Murielle Gregoire , Fabrice Uhel , Arnaud Gacouin et al.
Critical Care, 2021, 25 (1), pp.9. ⟨10.1186/s13054-020-03444-x⟩
Article dans une revue hal-03134918 v1
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Impact of HIV-1 Vpr manipulation of the DNA repair enzyme UNG2 on B lymphocyte class switch recombination

Patrick Eldin , Sophie Péron , Anastasia Galashevskaya , Nicolas Denis-Lagache , Michel Cogné et al.
Journal of Translational Medicine, 2020, 18 (1), ⟨10.1186/s12967-020-02478-7⟩
Article dans une revue hal-02914967 v1
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An Engineered Human Fc Domain that Behaves like a pH-Toggle Switch for Ultra-Long Circulation Persistence

Tae Hyun Kang , Chang-Han Lee , Tae Hyun Kang , Ophélie Godon , Makiko Watanabe et al.
Nature Communications, 2019, 10 (1), pp.5031. ⟨10.1038/s41467-019-13108-2⟩
Article dans une revue pasteur-02448624 v1

IgH locus suicide recombination does not depend on NHEJ in contrast to CSR in B cells

Nour Ghazzaui , Hussein Issaoui , Ophélie Alyssa Martin , Alexis Saintamand , Yves Denizot et al.
Cellular and molecular immunology, 2019, 16 (2), pp.201-202. ⟨10.1038/s41423-018-0172-2⟩
Article dans une revue hal-02343984 v1
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Locus suicide recombination actively occurs on the functionally rearranged IgH allele in B- cells from inflamed human lymphoid tissues

Iman Dalloul , François Boyer , Zeinab Dalloul , Amandine Pignarre , Gersende Caron et al.
PLoS ONE, 2019, 15 (6), pp.e1007721. ⟨10.1371/journal.pgen.1007721⟩
Article dans une revue inserm-02273760 v1

Mesangial Deposition Can Strongly Involve Innate-Like IgA Molecules Lacking Affinity Maturation

Batoul Wehbi , Christelle Oblet , François Boyer , Arnaud Huard , Anne Druilhe et al.
Journal of the American Society of Nephrology, 2019, 30 (7), pp.1238-1249. ⟨10.1681/ASN.2018111089⟩
Article dans une revue hal-02361794 v1

Mediator contributes to IgH locus VDJ rearrangements by promoting usage of most distal V segments

Iman Dalloul , Zeinab Dalloul , Sandrine Le Noir , François Boyer , Bernardo Reina-San-Martin et al.
Cellular and molecular immunology, 2018, ⟨10.1038/s41423-018-0175-z⟩
Article dans une revue hal-02343957 v1

Comprehensive molecular characterization of a heavy chain deposition disease case

Sébastien Bender , Maria Victoria Ayala , Vincent Javaugue , Amélie Bonaud , Michel Cogné et al.
Haematologica, 2018, 103 (11), pp.e557-e560. ⟨10.3324/haematol.2018.196113⟩
Article dans une revue hal-02343962 v1
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<i>PAX5A</i> and <i>PAX5B</i> isoforms are both efficient to drive B cell differentiation

Charlotte Cresson , Sophie Péron , Laura Jamrog , Nelly Rouquié , Nais Prade et al.
Oncotarget, 2018, 9 (67), pp.32841-32854. ⟨10.18632/oncotarget.26003⟩
Article dans une revue hal-02566158 v1

<i>PAX5A</i> and <i>PAX5B</i> isoforms are both efficient to drive B cell differentiation

Charlotte Cresson , Sophie Péron , Laura Jamrog , Nelly Rouquié , Nais Prade et al.
Oncotarget, 2018, 9 (67), ⟨10.18632/oncotarget.26003⟩
Article dans une revue hal-02343994 v1

Detecting Rare AID-Induced Mutations in B-Lineage Oncogenes from High-Throughput Sequencing Data Using the Detection of Minor Variants by Error Correction Method

Ophélie Alyssa Martin , Armand Garot , Sandrine Le Noir , Jean-Claude Aldigier , Michel Cogné et al.
Journal of Immunology, 2018, 201 (3), pp.950-956. ⟨10.4049/jimmunol.1800203⟩
Article dans une revue hal-02344000 v1

G-quadruplex DNA targeting alters class-switch recombination in B cells and attenuates allergic inflammation

Zeinab Dalloul , Pauline Chenuet , Iman Dalloul , François Boyer , Jean-Claude Aldigier et al.
Journal of Allergy and Clinical Immunology, 2018, 142 (4), pp.1352-1355. ⟨10.1016/j.jaci.2018.06.011⟩
Article dans une revue hal-02343989 v1

Animal models of monoclonal immunoglobulin-related renal diseases

Christophe Sirac , Guillermo Herrera , Paul Sanders , Vecihi Batuman , Sébastien Bender et al.
Nature Reviews Nephrology, 2018, 14 (4), pp.246-264. ⟨10.1038/nrneph.2018.8⟩
Article dans une revue hal-02344013 v1

Physiological and druggable skipping of immunoglobulin variable exons in plasma cells

Mohamad Omar Ashi , Nivine Srour , Jean-Marie Lambert , Anne Marchalot , Ophélie Martin et al.
Cellular and molecular immunology, 2018, ⟨10.1038/s41423-018-0160-6⟩
Article dans une revue hal-02048156 v1

Unravelling the immunopathological mechanisms of heavy chain deposition disease with implications for clinical management

Frank Bridoux , Vincent Javaugue , Sébastien Bender , Fannie Leroy , Pierre Aucouturier et al.
Kidney International, 2017, 91 (2), pp.423-434. ⟨10.1016/j.kint.2016.09.004⟩
Article dans une revue hal-02364147 v1
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Eμ and 3'RR IgH enhancers show hierarchic unilateral dependence in mature B-cells

Alexis Saintamand , Christelle Vincent-Fabert , Marie Marquet , Nour Ghazzaui , Virginie Magnone et al.
Scientific Reports, 2017, 7 (1), pp.442. ⟨10.1038/s41598-017-00575-0⟩
Article dans une revue hal-01517051 v1
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Characterization of human FCRL4-positive B cells

Michel Jourdan , Nicolas Robert , Maïlys Cren , Coraline Thibaut , Christophe Duperray et al.
PLoS ONE, 2017, 12 (6), pp.e0179793. ⟨10.1371/journal.pone.0179793⟩
Article dans une revue hal-01560458 v1

Impaired Lysosomal Function Underlies Monoclonal Light Chain–Associated Renal Fanconi Syndrome

Alessandro Luciani , Christophe Sirac , Sara Terryn , Vincent Javaugue , Jenny Ann Prange et al.
Journal of the American Society of Nephrology, 2016, 27 (7), pp.2049-2061. ⟨10.1681/ASN.2015050581⟩
Article dans une revue hal-02364437 v1

Loss of the HVEM Tumor Suppressor in Lymphoma and Restoration by Modified CAR-T Cells

Michael Boice , Darin Salloum , Frédéric Mourcin , Viraj Sanghvi , Rada Amin et al.
Cell, 2016, 167 (2), pp.405-418 e13. ⟨10.1016/j.cell.2016.08.032⟩
Article dans une revue hal-01405853 v1
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A plasma cell differentiation quality control ablates B cell clones with biallelic Ig rearrangements and truncated Ig production

Nivine Srour , Guillaume Chemin , Aurélien Tinguely , Mohamad Omar Ashi , Zéliha Oruc et al.
Journal of Experimental Medicine, 2016, 213 (1), pp.109-122. ⟨10.1084/jem.20131511⟩
Article dans une revue hal-01501807 v1

First Membrane Proximal External Region-Specific Anti-HIV1 Broadly Neutralizing Monoclonal IgA1 Presenting Short CDRH3 and Low Somatic Mutations.

Fahd Benjelloun , Zéliha Oruc , Nicole M. Thielens , Bernard Verrier , Gael Champier et al.
Journal of Immunology, 2016, 197 (5), pp.1979-88. ⟨10.4049/jimmunol.1600309⟩
Article dans une revue hal-01356638 v1

Sequential activation and distinct functions for distal and proximal modules within the IgH 3′ regulatory region

Armand Garot , Marie Marquet , Alexis Saintamand , Sébastien Bender , Sandrine Le Noir et al.
Proceedings of the National Academy of Sciences of the United States of America, 2016, 113 (6), pp.1618-1623. ⟨10.1073/pnas.1514090113⟩
Article dans une revue hal-02364206 v1

IgA Structure Variations Associate with Immune Stimulations and IgA Mesangial Deposition

Zéliha Oruc , Christelle Oblet , Ahmed Boumédiène , Anne Druilhe , Virginie Pascal et al.
Journal of the American Society of Nephrology, 2016, 27 (9), pp.2748-2761. ⟨10.1681/ASN.2015080911⟩
Article dans une revue hal-01269915 v1
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The contribution of virtual reality to the diagnosis of spatial navigation disorders and to the study of the role of navigational aids: A systematic literature review.

Michel Cogné , Mathieu Taillade , Bernard N'Kaoua , Annabelle Tarruella , Evelyne Klinger et al.
Annals of Physical and Rehabilitation Medicine, 2016, ⟨10.1016/j.rehab.2015.12.004⟩
Article dans une revue hal-01354011 v1

Quand les gènes codant les anticorps s’adjoignent des fragments venus d’autres chromosomes

Brice Laffleur , Zeinab Dalloul , Iman Dalloul , Sandrine Le Noir , Michel Cogné
Médecine/Sciences, 2016, 32 (8-9), pp.677-680. ⟨10.1051/medsci/20163208006⟩
Article dans une revue hal-02364198 v1
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Deciphering the importance of the palindromic architecture of the immunoglobulin heavy-chain 3’ regulatory region

Alexis Saintamand , Christelle Vincent-Fabert , Armand Garot , Pauline Rouaud , Zéliha Oruc et al.
Nature Communications, 2016, 7, pp.10730. ⟨10.1038/ncomms10730⟩
Article dans une revue hal-01442466 v1

Self-control for IgE production.

Brice Laffleur , Michel Cogné
Oncotarget, 2015
Article dans une revue hal-01212546 v1

A mouse model recapitulating human monoclonal heavy chain deposition disease evidences the relevance of proteasome inhibitor therapy.

Amélie Bonaud , Sébastien Bender , G Touchard , C Lacombe , Nivine Srour et al.
Blood, 2015
Article dans une revue hal-01212560 v1

Comment on "IgH chain class switch recombination: mechanism and regulation".

Alexis Saintamand , Jc Lecron , Frédéric Morel , Michel Cogné , Yves Denizot
Journal of Immunology, 2015
Article dans une revue hal-01212327 v1
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Self-Restrained B Cells Arise following Membrane IgE Expression

Brice Laffleur , Sophie Duchez , Karin Tarte , Nicolas Denis-Lagache , Sophie Péron et al.
Cell Reports, 2015, 10 (6), pp.900-909. ⟨10.1016/j.celrep.2015.01.023⟩
Article dans une revue hal-01116949 v1

Efficient AID targeting of switch regions is not sufficient for optimal class switch recombination.

Amélie Bonaud , Fabien Lechouane , S Le Noir , O Monestier , Michel Cogné et al.
Nature Communications, 2015
Article dans une revue hal-01212525 v1

The IgH 3' regulatory region governs μ chain transcription in mature B lymphocytes and the B cell fate.

Alexis Saintamand , Pauline Rouaud , Armand Garot , Faten Saad , Claire Carrion et al.
Oncotarget, 2015
Article dans une revue hal-01212314 v1

Elucidation of IgH 3' region regulatory role during class switch recombination via germline deletion.

Alexis Saintamand , Pauline Rouaud , Faten Saad , G Rios , Michel Cogné et al.
Nature Communications, 2015
Article dans une revue hal-01212563 v1
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Developmental Switch in the Transcriptional Activity of a Long-Range Regulatory Element

Fatima-Zohra Braikia , Caroline Conte , Mohamed Moutahir , Yves Denizot , Michel Cogné et al.
Molecular and Cellular Biology, 2015, 35 (19), pp.3370-3380. ⟨10.1128/mcb.00509-15⟩
Article dans une revue hal-01501824 v1

Immunoglobulin genes undergo legitimate repair in human B cells not only after cis- but also frequent trans-class switch recombination.

Brice Laffleur , Sylvia M. Bardet , Armand Garot , M Brousse , A Baylet et al.
Genes and Immunity, 2014, 15 (5), pp.341-6. ⟨10.1038/gene.2014.25⟩
Article dans une revue hal-01112042 v1
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The class-specific BCR tonic signal modulates lymphomagenesis in a c-myc deregulation transgenic model.

Rada Amin , Abdelghafour Marfak , Céline Pangault , Christelle Oblet , Aurélie Chanut et al.
Oncotarget, 2014, 5 (19), pp.8995-9006. ⟨10.18632/oncotarget.2297⟩
Article dans une revue hal-01067143 v1

Caractéristiques des IgA promptes à se déposer dans le mésangium

J.C. Aldigier , Zéliha Oruc , Christelle Oblet , Ahmed Boumédiène , Alexis Cuvillier et al.
Néphrologie & Thérapeutique, 2014, 10 (5), pp.282. ⟨10.1016/j.nephro.2014.07.354⟩
Article dans une revue hal-01117015 v1

Elucidation of the enigmatic IgD class-switch recombination via germline deletion of the IgH 3' regulatory region

Pauline Rouaud , Alexis Saintamand , Faten Saad , Claire Carrion , Sandrine Lecardeur et al.
Journal of Experimental Medicine, 2014
Article dans une revue hal-01212566 v1

The Eμ enhancer region influences H chain expression and B cell fate without impacting IgVH repertoire and immune response in vivo.

Marie Marquet , Armand Garot , Sébastien Bender , Claire Carrion , Pauline Rouaud et al.
Journal of Immunology, 2014, 193 (3), pp.1171-83. ⟨10.4049/jimmunol.1302868⟩
Article dans une revue hal-01110453 v1

Activation-induced deaminase in B lymphocyte maturation and beyond.

Michel Cogné
Biomed J, 2013, 36 (6), pp.259-68. ⟨10.4103/2319-4170.113191⟩
Article dans une revue hal-00945344 v1

The IgH 3' regulatory region controls somatic hypermutation in germinal center B cells.

Pauline Rouaud , Christelle Vincent-Fabert , Alexis Saintamand , Rémi Fiancette , Marie Marquet et al.
Journal of Experimental Medicine, 2013, 210 (8), pp.1501-7. ⟨10.1084/jem.20130072⟩
Article dans une revue hal-00903790 v1

IGHV gene features and MYD88 L265P mutation separate the three marginal zone lymphoma entities and Waldenström macroglobulinemia/lymphoplasmacytic lymphomas.

Nathalie Gachard , M. Parrens , Isabelle Soubeyran , Barbara Petit , A. Marfak et al.
Leukemia, 2013, 27 (1), pp.183-9. ⟨10.1038/leu.2012.257⟩
Article dans une revue hal-00779407 v1

Flexible long-range loops in the VH gene region of the Igh locus facilitate the generation of a diverse antibody repertoire.

Jasna Medvedovic , Anja Ebert , Hiromi Tagoh , Ido M Tamir , Tanja A Schwickert et al.
Immunity, 2013, 39 (2), pp.229-44. ⟨10.1016/j.immuni.2013.08.011⟩
Article dans une revue hal-00903793 v1

Abnormal apical-to-basal transport of dietary ovalbumin by secretory IgA stimulates a mucosal Th1 response.

J. Abed , C. Lebreton , G. Champier , Alexis Cuvillier , Michel Cogné et al.
Mucosal Immunology, 2013, epub ahead of print. ⟨10.1038/mi.2013.49⟩
Article dans une revue hal-00903792 v1

Deletion of the α immunoglobulin chain membrane-anchoring region reduces but does not abolish IgA secretion.

Rada Amin , Claire Carrion , Catherine Decourt , Eric Pinaud , Michel Cogné
Immunology, 2012, 136 (1), pp.54-63. ⟨10.1111/j.1365-2567.2012.03557.x⟩
Article dans une revue hal-00696503 v1

Production of human or humanized antibodies in mice.

Brice Laffleur , Virginie Pascal , Christophe Sirac , Michel Cogné
Methods in Molecular Biology, 2012, 901, pp.149-59. ⟨10.1007/978-1-61779-931-0_9⟩
Article dans une revue hal-00779395 v1

Specific impairment of proximal tubular cell proliferation by a monoclonal κ light chain responsible for Fanconi syndrome.

Chahrazed El Hamel , Jean-Claude Aldigier , Christelle Oblet , Brice Laffleur , Franck Bridoux et al.
Nephrology Dialysis Transplantation, 2012, 27 (12), pp.4368-77. ⟨10.1093/ndt/gfs261⟩
Article dans une revue hal-00779410 v1

A defect of the INK4-Cdk4 checkpoint and Myc collaborate in blastoid mantle cell lymphoma-like lymphoma formation in mice.

Christelle Vincent-Fabert , Rémi Fiancette , Pauline Rouaud , Christel Baudet , Véronique Truffinet et al.
American Journal of Pathology, 2012, 180 (4), pp.1688-701. ⟨10.1016/j.ajpath.2012.01.004⟩
Article dans une revue hal-00696495 v1

[IgH locus suicide recombination, or when B cells surrender!].

Sophie Péron , Brice Laffleur , Nicolas Denis-Lagache , Jeanne Cook-Moreau , Matthieu Filloux et al.
Médecine/Sciences, 2012, 28 (5), pp.551-4. ⟨10.1051/medsci/2012285023⟩
Article dans une revue hal-00779352 v1

AID-Driven Deletion Causes Immunoglobulin Heavy Chain "Locus Suicide Recombination" in B Cells.

Sophie Péron , Brice Laffleur , Nicolas Denis-Lagache , Jeanne Cook-Moreau , Aurélien Tinguely et al.
Science, 2012, epub ahead of print. ⟨10.1126/science.1218692⟩
Article dans une revue hal-00697665 v1

Class-specific effector functions of therapeutic antibodies.

Virginie Pascal , Brice Laffleur , Michel Cogné
Methods in Molecular Biology, 2012, 901, pp.295-317. ⟨10.1007/978-1-61779-931-0_19⟩
Article dans une revue hal-00779398 v1

Cross talk between immunoglobulin heavy-chain transcription and RNA surveillance during B cell development.

Aurélien Tinguely , Guillaume Chemin , Sophie Péron , Christophe Sirac , Stéphane Reynaud et al.
Molecular and Cellular Biology, 2012, 32 (1), pp.107-17. ⟨10.1128/MCB.06138-11⟩
Article dans une revue hal-00696497 v1

Mantle cell lymphoma-like lymphomas in c-myc-3'RR/p53+/- mice and c-myc-3'RR/Cdk4R24C mice: differential oncogenic mechanisms but similar cellular origin.

Pauline Rouaud , Rémi Fiancette , Christelle Vincent-Fabert , Virginie Magnone , Michel Cogné et al.
Oncotarget, 2012, 3 (5), pp.586-93
Article dans une revue hal-00779350 v1

Anti-CD20 IgA can protect mice against lymphoma development: evaluation of the direct impact of IgA and cytotoxic effector recruitment on CD20 target cells.

Virginie Pascal , Brice Laffleur , Arnaud Debin , Armelle Cuvillier , Marjolein van Egmond et al.
Haematologica, 2012, 97 (11), pp.1686-94. ⟨10.3324/haematol.2011.061408⟩
Article dans une revue hal-00779391 v1

B-cell receptor signal strength influences terminal differentiation.

Fabien Lechouane , Amélie Bonaud , Laurent Delpy , Stefano Casola , Zéliha Oruc et al.
European Journal of Immunology, 2012, epub ahead of print. ⟨10.1002/eji.201242912⟩
Article dans une revue hal-00779414 v1

Enhancers located in heavy chain regulatory region (hs3a, hs1,2, hs3b, and hs4) are dispensable for diversity of VDJ recombination.

Pauline Rouaud , Christelle Vincent-Fabert , Rémi Fiancette , Michel Cogné , Eric Pinaud et al.
Journal of Biological Chemistry, 2012, 287 (11), pp.8356-60. ⟨10.1074/jbc.M112.341024⟩
Article dans une revue hal-00696502 v1
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Transglutaminase is essential for IgA nephropathy development acting through IgA receptors.

Laureline Berthelot , Christina Papista , Thiago T Maciel , Martine Biarnes-Pelicot , Emilie Tissandie et al.
Journal of Experimental Medicine, 2012, 209 (4), pp.793-806. ⟨10.1084/jem.20112005⟩
Article dans une revue hal-00903832 v1

Toward understanding renal Fanconi syndrome: step by step advances through experimental models.

Christophe Sirac , Franck Bridoux , Marie Essig , Olivier Devuyst , Guy Touchard et al.
Contributions to Nephrology, 2011, 169, pp.247-61. ⟨10.1159/000313962⟩
Article dans une revue hal-00696465 v1

A p53 defect sensitizes various stages of B cell development to lymphomagenesis in mice carrying an IgH 3' regulatory region-driven c-myc transgene.

Rémi Fiancette , Pauline Rouaud , Christelle Vincent-Fabert , Brice Laffleur , Virginie Magnone et al.
Journal of Immunology, 2011, 187 (11), pp.5772-82. ⟨10.4049/jimmunol.1102059⟩
Article dans une revue hal-00696493 v1

The IgH locus 3' regulatory region: pulling the strings from behind.

Eric Pinaud , Marie Marquet , Rémi Fiancette , Sophie Péron , Christelle Vincent-Fabert et al.
Advances in immunology, 2011, 110, pp.27-70. ⟨10.1016/B978-0-12-387663-8.00002-8⟩
Article dans une revue hal-00696444 v1

Glycotranscriptome study reveals an enzymatic switch modulating glycosaminoglycan synthesis during B cell development and activation.

Sophie Duchez , Virginie Pascal , Nadine Cogné , Chantal Jayat-Vignoles , Raymond Julien et al.
European Journal of Immunology, 2011, 41 (12), epub ahead of print. ⟨10.1002/eji.201140865⟩
Article dans une revue hal-00696483 v1

Strategies to model AL amyloidosis in mice.

Christophe Sirac , Sébastien Bender , Arnaud Jaccard , Franck Bridoux , C. Lacombe et al.
Amyloid: The Journal of Protein Folding Disorders, 2011, 18 (Suppl 1), pp.45-47. ⟨10.3109/13506129.2011.574354016⟩
Article dans une revue hal-00617188 v2

Glycotranscriptome study reveals an enzymatic switch modulating glycosaminoglycan synthesis during B-cell development and activation

Sophie Duchez , Virginie Pascal , Nadine Cogné , Chantal Jayat-Vignoles , Raymond Julien et al.
European Journal of Immunology, 2011, 41 (12), pp.3632-3644. ⟨10.1002/eji.201140865⟩
Article dans une revue hal-01211951 v1

Similarity of fine specificity of IgA anti-gliadin antibodies between patients with celiac disease and humanized α1KI mice.

Daniel Sánchez , Gaël Champier , Armelle Cuvillier , Michel Cogné , Aneta Pekáriková et al.
Journal of Agricultural and Food Chemistry, 2011, 59 (7), pp.3092-100. ⟨10.1021/jf1044519⟩
Article dans une revue hal-00696473 v1

Complexes between nuclear factor-κB p65 and signal transducer and activator of transcription 3 are key actors in inducing activation-induced cytidine deaminase expression and immunoglobulin A production in CD40L plus interleukin-10-treated human blood B cells.

S. Lafarge , H. Hamzeh-Cognasse , Y. Richard , B. Pozzetto , Michel Cogné et al.
Clinical and Experimental Immunology, 2011, 166 (2), pp.171-83. ⟨10.1111/j.1365-2249.2011.04465.x⟩
Article dans une revue hal-00697663 v1

Polymeric IgA1 controls erythroblast proliferation and accelerates erythropoiesis recovery in anemia.

S. Coulon , M. Dussiot , D. Grapton , Trovati Maciel T. , Huey Mei Wang P. et al.
Nature Medicine, 2011, 17, pp.1456-1465
Article dans une revue hal-00617557 v1

Gammopathy with IgA mesangial deposition provides a monoclonal model of IgA nephritogenicity and offers new insights into its molecular mechanisms.

Ahmed Boumédiène , Christelle Oblet , Zéliha Oruc , Sophie Duchez , Willy Morelle et al.
Nephrology Dialysis Transplantation, 2011, 26 (12), pp.3930-7. ⟨10.1093/ndt/gfr131⟩
Article dans une revue hal-00696463 v1

Polymeric IgA1 controls erythroblast proliferation and accelerates erythropoiesis recovery in anemia.

Séverine Coulon , Michaël Dussiot , Damien Grapton , Thiago Trovati Maciel , Pamella Huey Mei Wang et al.
Nature Medicine, 2011, 17 (11), pp.1456-65. ⟨10.1038/nm.2462⟩
Article dans une revue hal-00696490 v1

A myeloma translocation-like model associating CCND1 with the immunoglobulin heavy-chain locus 3' enhancers does not promote by itself B-cell malignancies.

Rémi Fiancette , Rada Amin , Véronique Truffinet , Christelle Vincent-Fabert , Nadine Cogné et al.
Leukemia Research, 2010, 34 (8), pp.1043-51. ⟨10.1016/j.leukres.2009.11.017⟩
Article dans une revue istex hal-00514237 v1

Premature replacement of {micro} with {alpha} immunoglobulin chains impairs lymphopoiesis and mucosal homing but promotes plasma cell maturation.

Sophie Duchez , Rada Amin , Nadine Cogné , Laurent Delpy , Christophe Sirac et al.
Proceedings of the National Academy of Sciences of the United States of America, 2010, epub ahead of print. ⟨10.1073/pnas.0912393107⟩
Article dans une revue hal-00454129 v1

Crystal-storing histiocytosis with renal Fanconi syndrome: pathological and molecular characteristics compared with classical myeloma-associated Fanconi syndrome.

Chahrazed El Hamel , Antoine Thierry , Patrick Trouillas , Franck Bridoux , Claire Carrion et al.
Nephrology Dialysis Transplantation, 2010, 25 (9), pp.2982-90. ⟨10.1093/ndt/gfq129⟩
Article dans une revue hal-00514235 v1

Multiple RNA surveillance mechanisms cooperate to reduce the amount of nonfunctional Ig kappa transcripts.

Guillaume Chemin , Aurélien Tinguely , Christophe Sirac , Fabien Lechouane , Sophie Duchez et al.
Journal of Immunology, 2010, 184 (9), pp.5009-17. ⟨10.4049/jimmunol.0902949⟩
Article dans une revue hal-00511941 v1

The IgH 3' regulatory region and its implication in lymphomagenesis.

Christelle Vincent-Fabert , Rémi Fiancette , Michel Cogné , Eric Pinaud , Yves Denizot
European Journal of Immunology, 2010, 40 (12), pp.3306-11. ⟨10.1002/eji.201040778⟩
Article dans une revue hal-00559583 v1

Genomic deletion of the whole IgH 3' regulatory region (hs3a, hs1,2, hs3b, hs4) dramatically affects class switch recombination and Ig secretion to all isotypes.

Christelle Vincent-Fabert , Rémi Fiancette , Eric Pinaud , Véronique Truffinet , Nadine Cogné et al.
Blood, 2010, epub ahead of print. ⟨10.1182/blood-2010-01-264689⟩
Article dans une revue hal-00514236 v1

In vivo redundant function of the 3' IgH regulatory element HS3b in the mouse.

Anne-Gaëlle Bébin , Claire Carrion , Marie Marquet , Nadine Cogné , Sandrine Lecardeur et al.
Journal of Immunology, 2010, 184 (7), pp.3710-7. ⟨10.4049/jimmunol.0901978⟩
Article dans une revue hal-00514232 v1

[Physiopathology of bullous pemphigoid]

V. Doffoel-Hantz , Michel Cogné , M. Drouet , Agnès Sparsa , J.-M. Bonnetblanc et al.
Annales de Dermatologie et de Vénéréologie, 2009, 136 (10), pp.740-7; quiz 739, 748. ⟨10.1016/j.annder.2008.10.044⟩
Article dans une revue hal-00452834 v1
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Transgenesis and humanization of murine antibodies.

Michel Cogné , Sophie Duchez , Virginie Pascal
Médecine/Sciences, 2009, 25 (12), pp.1149-54
Article dans une revue hal-00443792 v1

Uncoupling between Ig somatic hypermutation and oncogene mutation in mouse lymphoma.

Christelle Vincent-Fabert , Véronique Truffinet , Rémi Fiancette , Barbara Petit , Nadine Cogné et al.
Biochimica et Biophysica Acta - Molecular Cell Research, 2009, 1793 (2), pp.418-26. ⟨10.1016/j.bbamcr.2008.10.011⟩
Article dans une revue istex hal-00363954 v1

Ig synthesis and class switching do not require the presence of the hs4 enhancer in the 3' IgH regulatory region.

Christelle Vincent-Fabert , Véronique Truffinet , Rémi Fiancette , Nadine Cogné , Michel Cogné et al.
Journal of Immunology, 2009, 182 (11), pp.6926-32. ⟨10.4049/jimmunol.0900214⟩
Article dans une revue hal-00443742 v1

Genetic background modulates susceptibility to oncogen-driven proliferation and lymphoma occurrence in mice carrying a deregulated c-myc transgene.

Christelle Vincent-Fabert , Rémi Fiancette , Véronique Truffinet , Nadine Cogné , Michel Cogné et al.
Leukemia Research, 2009, 33 (11), pp.e203-6. ⟨10.1016/j.leukres.2009.05.018⟩
Article dans une revue istex hal-00514240 v1

Long-range oncogenic activation of Igh-c-myc translocations by the Igh 3' regulatory region.

Monica Gostissa , Catherine T Yan , Julia M Bianco , Michel Cogné , Eric Pinaud et al.
Nature, 2009, 462 (7274), pp.803-7. ⟨10.1038/nature08633⟩
Article dans une revue hal-00443754 v1

[Physiopathology of herpetiform dermatitis. Current data]

V. Doffoel-Hantz , Michel Cogné , Agnès Sparsa , J.-M. Bonnetblanc , Mireille Drouet et al.
Annales de Dermatologie et de Vénéréologie, 2008, 135 (11), pp.784-8; quiz 783. ⟨10.1016/j.annder.2008.02.030⟩
Article dans une revue hal-00363969 v1

Splenic marginal zone lymphomas and lymphoplasmacytic lymphomas originate from B-cell compartments with two different antigen-exposure histories.

M. Parrens , Nathalie Gachard , Barbara Petit , A. Marfak , E. Troadec et al.
Leukemia, 2008, 22 (8), pp.1621-4. ⟨10.1038/leu.2008.24⟩
Article dans une revue hal-00364488 v1

High-dose melphalan versus melphalan plus dexamethasone for AL amyloidosis.

Arnaud Jaccard , Philippe Moreau , Véronique Leblond , Xavier Leleu , Lofti Benboubker et al.
New England Journal of Medicine, 2007, 357 (11), pp.1083-93
Article dans une revue hal-00172895 v1

Clinico-biological characteristics of flow cytometry applied to hypersensitivity to NSAIDs.

J. Sainte-Laudy , F. Touraine , Ahmed Boumédiène , F. Bonnaud , Michel Cogné
Inflammation Research, 2007, 56 Suppl 1, pp.S63-4
Article dans une revue hal-00452811 v1

S-S synapsis during class switch recombination is promoted by distantly located transcriptional elements and activation-induced deaminase.

Robert Wuerffel , Lili Wang , Fernando Grigera , John Manis , Erik Selsing et al.
Immunity, 2007, 27 (5), pp.711-22. ⟨10.1016/j.immuni.2007.09.007⟩
Article dans une revue hal-00363968 v1

The 3' IgH locus control region is sufficient to deregulate a c-myc transgene and promote mature B cell malignancies with a predominant Burkitt-like phenotype.

Véronique Truffinet , Eric Pinaud , Nadine Cogné , Barbara Petit , Laurence Guglielmi et al.
Journal of Immunology, 2007, 179 (9), pp.6033-6042
Article dans une revue hal-00181178 v1

Use of both CD63 up regulation and IgE down regulation for the flow cytometric analysis of allergen induced basophil activation. Definition of an activation index.

Jean Sainte-Laudy , Ahmed Boumédiène , F. Touraine , Isabelle Orsel , C. Brianchon et al.
Inflammation Research, 2007, 56 (7), pp.291-6. ⟨10.1007/s00011-007-7014-5⟩
Article dans une revue istex hal-00166018 v1

Interallelic class switch recombination can reverse allelic exclusion and allow trans-complementation of an IgH locus switching defect.

Hei-Lanne Dougier , Stéphane Reynaud , Eric Pinaud , Claire Carrion , Laurent Delpy et al.
European Journal of Immunology, 2006, 36 (8), pp.2181-91. ⟨10.1002/eji.200535529⟩
Article dans une revue hal-00088115 v1

Polyclonal IgG4 hypergammaglobulinemia associated with plasmacytic lymphadenopathy, anemia and nephropathy.

Emmanuelle Boulanger , Vincent Fuentes , Véronique Meignin , Béatrice Mougenot , Sylvaine Labaume et al.
Annals of Hematology, 2006, 85 (12), pp.833-40. ⟨10.1007/s00277-006-0158-5⟩
Article dans une revue istex hal-00451895 v1

Germ line transcription in mice bearing neor gene downstream of Igamma3 exon in the Ig heavy chain locus.

Maha Samara , Zéliha Oruc , Hei-Lanne Dougier , Tawer Essawi , Michel Cogné et al.
International Immunology, 2006, 18 (4), pp.581-589. ⟨10.1093/intimm/dxh400⟩
Article dans une revue hal-00021571 v1

Light chain inclusion permits terminal B cell differentiation and does not necessarily result in autoreactivity.

Christophe Sirac , Claire Carrion , Sophie Duchez , Isabelle Comte , Michel Cogné
Proceedings of the National Academy of Sciences of the United States of America, 2006, 103 (20), pp.7747-52. ⟨10.1073/pnas.0509121103⟩
Article dans une revue hal-00073857 v1

Role of the monoclonal kappa chain V domain and reversibility of renal damage in a transgenic model of acquired Fanconi syndrome.

Christophe Sirac , Franck Bridoux , Claire Carrion , Olivier Devuyst , Béatrice Fernandez et al.
Blood, 2006, 108 (2), pp.536-543. ⟨10.1182/blood-2005-11-4419⟩
Article dans une revue hal-00085051 v1

Platelet activation after aortic prosthetic valve surgery.

Alexandre Leguyader , Reina Watanabe , Julien Berbé , Ahmed Boumédiène , Michel Cogné et al.
Interactive Cardiovascular and Thoracic Surgery, 2006, 5 (1), pp.60-4. ⟨10.1510/icvts.2005.115733⟩
Article dans une revue hal-00452815 v1

Analysis of IgE down regulation induced by basophil activation. Application to the diagnosis of muscle relaxant allergic hypersensitivity by flow cytometry.

J. Sainte-Laudy , Ahmed Boumédiène , F. Touraine , I. Orsel , Michel Cogné
Inflammation Research, 2006, 55 Suppl 1, pp.S21-2. ⟨10.1007/s00011-005-0023-3⟩
Article dans une revue istex hal-00452816 v1

Interallelic Class Switch Recombination Contributes Significantly to Class Switching in Mouse B Cells

Stéphane Reynaud , Laurent Delpy , Laurence Fleury , Hei-Lanne Dougier , Christophe Sirac et al.
Journal of Immunology, 2005, 174, pp.5905-5906
Article dans une revue hal-00022865 v1

Interallelic class switch recombination contributes significantly to class switching in mouse B cells.

Stéphane Reynaud , Laurent Delpy , Laurence Fleury , Hei-Lanne Dougier , Christophe Sirac et al.
Journal of Immunology, 2005, 174 (10), pp.6176-83
Article dans une revue hal-00458866 v1

Fanconi's syndrome induced by a monoclonal Vkappa3 light chain in Waldenstrom's macroglobulinemia.

Franck Bridoux , Christophe Sirac , V. Hugue , Catherine Decourt , A. Thierry et al.
American Journal of Kidney Diseases, 2005, 45 (4), pp.749-57. ⟨10.1053/j.ajkd.2004.12.020⟩
Article dans une revue hal-00022808 v1

Indolent lymphoplasmacytic and marginal zone B-cell lymphomas: absence of both IRF4 and Ki67 expression identifies a better prognosis subgroup.

Barbara Petit , Mp Chaury , Arnaud Jaccard , Nathalie Gachard , S. Moalic-Judge et al.
Haematologica, 2005, 90(2), pp.200-6
Article dans une revue hal-00022403 v1
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The 5′HS4 insulator element is an efficient tool to analyse the transient expression of an Eμ-GFP vector in a transgenic mouse model

Laurence Guglielmi , Véronique Truffinet , Claire Carrion , Marc Le Bert , Nadine Cogné et al.
Transgenic Research, 2005, 14(4), pp.361-364. ⟨10.1007/s11248-005-3239-7⟩
Article dans une revue hal-00023265 v1

The chicken β-globin HS4 insulator is not a silver bullet to obtain copy-number dependent expression of transgenes in stable B cell transfectants

Véronique Truffinet , Laurence Guglielmi , Michel Cogné , Yves Denizot
Immunology Letters, 2005, 96(2), pp.303-4. ⟨10.1016/j.imlet.2004.09.002⟩
Article dans une revue istex hal-00022648 v1

Transcription-dependent somatic hypermutation occurs at similar levels on functional and nonfunctional rearranged IgH alleles.

Laurent Delpy , Christophe Sirac , Caroline Le Morvan , Michel Cogné
Journal of Immunology, 2004, 173 (3), pp.1842-8
Article dans une revue hal-00023372 v1

RNA surveillance down-regulates expression of nonfunctional kappa alleles and detects premature termination within the last kappa exon.

Laurent Delpy , Christophe Sirac , Emmanuelle Magnoux , Sophie Duchez , Michel Cogné
Proceedings of the National Academy of Sciences of the United States of America, 2004, 101 (19), pp.7375-80. ⟨10.1073/pnas.0305586101⟩
Article dans une revue hal-00023270 v1

Induction of somatic hypermutation by antigen-specific B cell receptors in the human BL2 cell line.

Florence Glaudet , Vincent Denis , Michel Cogné , Ahmed Amine Khamlichi
European Journal of Immunology, 2004, 34 (6), pp.1637-45. ⟨10.1002/eji.200324741⟩
Article dans une revue hal-00023350 v1

The polymorphism of the locus control region lying downstream the human IgH locus is restricted to hs1,2 but not to hs3 and hs4 enhancers.

Laurence Guglielmi , Véronique Truffinet , Emmanuelle Magnoux , Michel Cogné , Yves Denizot
Immunology Letters, 2004, 94 (1-2), pp.77-81. ⟨10.1016/j.imlet.2004.04.003⟩
Article dans une revue istex hal-00023366 v1

Immunoglobulin class-switch recombination in mice devoid of any S mu tandem repeat.

Ahmed Amine Khamlichi , Florence Glaudet , Zéliha Oruc , Vincent Denis , Marc Le Bert et al.
Blood, 2004, 103 (10), pp.3828-36. ⟨10.1182/blood-2003-10-3470⟩
Article dans une revue hal-00023269 v1

Immunologic basis for the rare occurrence of true nonsecretory plasma cell dyscrasias.

Catherine Decourt , Horia Radu Galea , Christophe Sirac , Michel Cogné
Journal of Leukocyte Biology, 2004, 76 (3), pp.528-36. ⟨10.1189/jlb.0803382⟩
Article dans une revue hal-00023271 v1

Effect of the Eμ IgH enhancer on expression of a GFP reporter gene in transfected B cells and transgenic mice

Laurence Guglielmi , Marc Le Bert , Michel Cogné , Yves Denizot
Immunology Letters, 2003, 86(1), pp.77-83. ⟨10.1016/S0165-2478(02)00264-X⟩
Article dans une revue istex hal-00023530 v1

The beta-globin HS4 insulator confers copy-number dependent expression of IgH regulatory elements in stable B cell transfectants.

Laurence Guglielmi , Véronique Truffinet , Michel Cogné , Yves Denizot
Immunology Letters, 2003, 89 (2-3), pp.119-23. ⟨10.1016/S0165-2478(03)00126-3⟩
Article dans une revue istex hal-00023379 v1

Germ-line transcription occurs on both the functional and the non-functional alleles of immunoglobulin constant heavy chain genes.

Laurent Delpy , Marc Le Bert , Michel Cogné , Ahmed Amine Khamlichi
European Journal of Immunology, 2003, 33 (8), pp.2108-13. ⟨10.1002/eji.200323969⟩
Article dans une revue hal-00023385 v1

Insulators to improve expression of a 3(')IgH LCR-driven reporter gene in transgenic mouse models.

Laurence Guglielmi , Marc Le Bert , Véronique Truffinet , Michel Cogné , Yves Denizot
Biochemical and Biophysical Research Communications, 2003, 307 (3), pp.466-71. ⟨10.1016/S0006-291X(03)01185-9⟩
Article dans une revue istex hal-00023524 v1

Combination of 3' and 5' IgH regulatory elements mimics the B-specific endogenous expression pattern of IgH genes from pro-B cells to mature B cells in a transgenic mouse model.

Laurence Guglielmi , Marc Le Bert , Isabelle Comte , Marie Laure Dessain , Mireille Drouet et al.
Biochimica et Biophysica Acta - Molecular Cell Research, 2003, 1642 (3), pp.181-90. ⟨10.1016/j.bbamcr.2003.08.005⟩
Article dans une revue istex hal-00023378 v1

The immunoglobulin heavy-chain locus hs3b and hs4 3' enhancers are dispensable for VDJ assembly and somatic hypermutation.

Caroline Le Morvan , Eric Pinaud , Catherine Decourt , Armelle Cuvillier , Michel Cogné
Blood, 2003, 102 (4), pp.1421-7. ⟨10.1182/blood-2002-12-3827⟩
Article dans une revue hal-00023823 v1

Nuclear factors, hs1,2 enhancer and IgA nephropathy.

Barbara Bessette , Laurence Guglielmi , Michel Cogné , Yves Denizot
Kidney International, 2003, 63 (2), pp.767. ⟨10.1046/j.1523-1755.2003.00789.x⟩
Article dans une revue hal-00023525 v1

A monoclonal V kappa l light chain responsible for incomplete proximal tubulopathy.

Catherine Decourt , Franck Bridoux , Guy Touchard , Michel Cogné
American Journal of Kidney Diseases, 2003, 41 (2), pp.497-504. ⟨10.1053/ajkd.2003.50062⟩
Article dans une revue hal-00023380 v1

192 and 55 paraoxonase-1 gene polymorphisms and coronary artery disease in Hemodialysis patients.

Thierry Dantoine , Michel Cogné , Jean-Pierre Charmes , Louis Merle , Mireille Drouet et al.
Clinical Journal of the American Society of Nephrology, 2002
Article dans une revue hal-01336537 v1

Light chain myeloma plasma cells induce a strong cell-mediated immune response mainly directed against the monoclonal light chain determinants in a murine experimental model.

Horia Galea , Yves Denizot , Michel Cogné
Cancer Immunology, Immunotherapy, 2002, 51 (4), pp.229-34. ⟨10.1007/s00262-002-0274-6⟩
Article dans une revue hal-00023825 v1

Analysis of three genetic markers in IgA nephropathy patients from a single region.

Mireille Drouet , V. Aupetit , Yves Denizot , M. Bois , Franck Bridoux et al.
Clinical Nephrology, 2002, 57 (4), pp.253-60. ⟨10.5414/cnp57253⟩
Article dans une revue hal-00023535 v1

Implication des facteurs vasculaires dans les troubles cognitifs du sujet âgé : relation entre le polymorphisme 192 de la paraoxonase 1 et la maladie d’Alzheimer.

Thierry Dantoine , M Drouet , J. Debord , H Lacroix , Louis Merle et al.
La Revue de Médecine Interne, 2002
Article dans une revue hal-01338479 v1

GM-CSF and IL-12 production by malignant plasma cells promotes cell-mediated immune responses against monoclonal Ig determinants in a light chain myeloma model.

H.R. Galea , Michel Cogné
Clinical and Experimental Immunology, 2002, 129 (2), pp.247-53. ⟨10.1046/j.1365-2249.2002.01929.x⟩
Article dans une revue hal-00023536 v1

Implication of paraoxonase-1 polymorphism 192 in Alzheimer’s disease.

Thierry Dantoine , J. Debord , M. Drouet , Louis Merle , Michel Cogné
Annals of the New York Academy of Sciences, 2002
Article dans une revue hal-01335856 v1

B cell development arrest upon insertion of a neo gene between JH and Emu: promoter competition results in transcriptional silencing of germline JH and complete VDJ rearrangements.

Laurent Delpy , Catherine Decourt , Marc Le Bert , Michel Cogné
Journal of Immunology, 2002, 169 (12), pp.6875-82
Article dans une revue hal-00023696 v1

Molecular study of an IgG1kappa cryoglobulin yielding organized microtubular deposits and glomerulonephritis in the course of chronic lymphocytic leukaemia.

H.R. Galea , Franck Bridoux , Jean-Claude Aldigier , François Paraf , Dominique Bordessoule et al.
Clinical and Experimental Immunology, 2002, 129 (1), pp.113-8. ⟨10.1046/j.1365-2249.2002.01896.x⟩
Article dans une revue hal-00023688 v1

Localization of the 3′ IgH Locus Elements that Effect Long-Distance Regulation of Class Switch Recombination

Eric Pinaud , Ahmed Amine Khamlichi , Caroline Le Morvan , Mireille Drouet , Valérie Nalesso et al.
Immunity, 2001, 15 (2), pp.187-199. ⟨10.1016/s1074-7613(01)00181-9⟩
Article dans une revue hal-03480612 v1

Characterization of the murine gene for subunit VIIaL of cytochrome c oxidase.

K. Chantrel-Groussard , Laurent Delpy , Marie-Hélène Ratinaud , Michel Cogné
Comptes rendus de l’Académie des sciences. Série III, Sciences de la vie, 2001, 324 (12), pp.1117-23
Article dans une revue hal-00458870 v1
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Heavy-Chain Deposition Disease

Pierre Aucouturier , Ahmed A Khamlichi , Guy Touchard , Eve Justrabo , Michel Cogné et al.
New England Journal of Medicine, 1993, 329 (19), pp.1389 - 1393. ⟨10.1056/NEJM199311043291905⟩
Article dans une revue inserm-01876787 v1
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Complementary DNA sequence of human amyloidogenic immunoglobulin light-chain precursors.

Pierre Aucouturier , Ahmed A Khamlichi , Jean-Louis Preud'Homme , Marc Bauwens , Guy Touchard et al.
Biochemical Journal, 1992, 285, pp.149-52. ⟨10.1042/bj2850149⟩
Article dans une revue inserm-01876794 v1
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Structure of a monoclonal kappa chain of the V kappa IV subgroup in the kidney and plasma cells in light chain deposition disease.

Michel Cogné , Jean-Louis Preud'Homme , Marc Bauwens , Guy Touchard , Pierre Aucouturier
Journal of Clinical Investigation, 1991, 87 (6), pp.2186 - 2190. ⟨10.1172/JCI115252⟩
Article dans une revue inserm-01876801 v1

Integrative Single-Cell RNA-Seq and Single-Cell ATAC-Seq Analysis of Human Plasma Cell Differentiation

Elina Alaterre , Sara Ovejero , Marion Espéli , Thierry Fest , Michel Cogné et al.
65th Annual Meeting of the American-Society-of-Hematology (ASH), Dec 2023, San Diego, United States. ⟨10.1182/blood-2023-181507⟩
Communication dans un congrès hal-04513440 v1

A Prospective Phase II Trial of Lenalidomide and Dexamethasone (Len-Dex) in POEMS Syndrome

Arnaud Jaccard , A. Danielou-Lazareth , L. Karlin , S. Choquet , L. Frenzel et al.
15th International Myeloma Workshop, Sep 2015, Rome, Italy. pp.e57, ⟨10.1016/j.clml.2015.07.197⟩
Communication dans un congrès hal-01228183 v1

Control of B cell fate after AID-mediated modulation of BCR expression

Michel Cogné
Symposium "Antibodies: the good, the bad, and the promising, Feb 2014, Amsterdam, Netherlands
Communication dans un congrès hal-00949511 v1

BCR expression and B Cell Fate

Michel Cogné
French Hematology Society 2014 congress, Mar 2014, Paris, France
Communication dans un congrès hal-00949513 v1

B cells switching to deadly paths

Michel Cogné
Henry Kunkel Society's 22nd Annual Meeting, "Human Immunology in Health and Disease, Apr 2014, New-York, United States
Communication dans un congrès hal-00949516 v1

Immunoglobulin genes in mature B cells: from biallelic accessibility to monoallelic expression

Michel Cogné
Symposium "Allelic gene regulation in health and disease", Feb 2013, Toulouse, France
Communication dans un congrès hal-00949506 v1

Modulation of B cell fate upon AID-mediated Ig gene recombination

Michel Cogné
3rd workshop normal and neoplastic B cells, Sep 2013, Oléron, France
Communication dans un congrès hal-00949547 v1

Breakthrough of high troughput studies in marginal zone lymphomas and Waldenström macroglobulinemia

Michel Cogné
3rd Workshop Normal and neoplastic B cells, Sep 2013, Oléron, France
Communication dans un congrès hal-00949548 v1

Symposium "Allelic gene regulation in health and disease

Michel Cogné
Fédération de Médecine Translationnelle de Strasbourg" (FMTS), Dec 2013, Strasbourg, France
Communication dans un congrès hal-00949510 v1

Locus suicide recombination in mature B cells

Michel Cogné
Keystone meeting "Mutations, Malignancy and Memory, Mar 2012, Boston, United States
Communication dans un congrès hal-00949503 v1

Locus suicide recombination in mature B cells

Michel Cogné
Mutations, Malignancy and Memory, Mar 2012, Boston, United States
Communication dans un congrès hal-00697686 v1

Regulation of immunoglobulin expression in mature B cells

Michel Cogné
International meeting on "B cells and Antibodies", Jerusalem, October 23-26, 2011, Oct 2011, Jésuralem, Israel
Communication dans un congrès hal-00949500 v1

Modèles murins d'étude mutationnelle du locus IgH et lymphomogenèse

Michel Cogné
1st French Lymphoma Workshop, Rennes, 20-21 janvier 2011, Jan 2011, Rennes, France
Communication dans un congrès hal-00949493 v1

Modèles murins d'étude mutationnelle du locus IgH et lymphomogenèse

Michel Cogné
1st French Lymphoma Workshop, Jan 2011, Rennes, France
Communication dans un congrès hal-00697680 v1

In vitro and in vivo evaluation of anti-CD20 antibodies shows the IgA class to surpass IgG for direct effect on target cells.

Michel Cogné
ACCITH Meeting "Antibodies and therapeutic targeting, Sep 2011, Strasbourg, France
Communication dans un congrès hal-00949494 v1

Regulation of immunoglobulin expression in mature B cells

Michel Cogné
International meeting on "B cells and Antibodies, Oct 2011, Jérusalem, Israel
Communication dans un congrès hal-00697685 v1

In vitro and in vivo evaluation of anti-CD20 antibodies shows the IgA class to surpass IgG for direct effect on target cells.

Michel Cogné
Forum "Anticorps et ciblage thérapeutique" du GDR ACCITH, Sep 2011, Strasbourg, France
Communication dans un congrès hal-00697682 v1

Production of IgA antibodies and their variants.

Michel Cogné
9th International Congress on Recombinant Antibodies 2010, Jun 2010, Berlin, Germany
Communication dans un congrès hal-00697674 v1

Régulation et dérégulation: les moteurs génétiques exposant le lymphocyte B à la perte de contrôle

Michel Cogné
21èmes journées de l'Association Nationale des Enseignants de Biologie Cellulaire, Sep 2010, Aubazine, France
Communication dans un congrès hal-00697678 v1

Régulation de l'expression du locus IGH et oncogenèse

Michel Cogné
Congrès 2010 du Club Hématopoièse et oncogenèse (CHO), Sep 2010, Giens, France
Communication dans un congrès hal-00697676 v1

Applying Cutting-Edge Antibody Engineering For the Development of New Generation of Humanised Antibodies

Michel Cogné
IQPC meeting on Therapeutic antibodies, Sep 2009, London, United Kingdom
Communication dans un congrès hal-00697672 v1

Autologus stern celle transplantation (ASCT) versus oral melphalan and high-dose dexamethasone in patients with AL (primary) amyloisdosis : results of the French multicentric randomized trial (MAG and IFM intergroup).

Arnaud Jaccard , P. Moreau , V. Leblond , X. Leleu , L Bennoubker et al.
Communication orale présentée à 'The American Society of Hematology 47th Annual meeting and Exposition", Dec 2005, Nouvelle Orléans (Louisiane), United States
Communication dans un congrès hal-01135622 v1

Rôle du polymorphisme génétique de la paraoxonase 1 dans la maladie d’Alzheimer.

Thierry Dantoine , Mireille Drouet , J. Debord , Michel Cogné , Louis Merle et al.
VIIème Congrès International Francophone de Gérontologie. Bruxelles, Belgique, 2002, Bruxelles, France
Communication dans un congrès hal-01336564 v1

Démence du sujet âgé et polymorphisme génétique de la paraoxonase 1.

Thierry Dantoine , C Puech , Mireille Drouet , J. Debord , Laurence Bernard-Bourzeix et al.
Société Française de Gériatrie et de Gérontologie, 2002, Limoges, France
Communication dans un congrès hal-01338464 v1

Polymorphisme génétique de la paraoxonase 1 et risque coronarien de l'insuffisant rénal chronique hémodialysé.

C Rebeyrotte , J. Debord , Mireille Drouet , Thierry Dantoine , Jean-Pierre Charmes et al.
Société de Néphrologie, 2000, Tours, France
Communication dans un congrès hal-01337138 v1

Atteintes uro-néphrologiques au cours des amyloses

Franck Bridoux , Arnaud Jaccard , Christophe Sirac , J. Gillmore , Michel Cogné et al.
Atteintes uro-néphrologiques au cours des maladies systémiques, Flammarion Médecine Sciences, pp.1-22, 2009
Chapitre d'ouvrage hal-00453323 v1

Renal disease in cryoglobulinemic vasculitis

Franck Bridoux , Christophe Sirac , Arnaud Jaccard , R. Abou Ayache , Jm Goujon et al.
The kidney in systemic autoimmune diseases, Elsevier, pp.215-240, 2008
Chapitre d'ouvrage hal-00453329 v1