Nadir Bettache

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Publications

FRET-based mesoporous organosilica nanoplatforms for in vitro and in vivo anticancer two-photon photodynamic therapy

Nicolas Bondon , Clément Charlot , Lamiaa Ali , Alexandre Barras , Nicolas Richy et al.
Journal of materials chemistry‎ B, 2025, ⟨10.1039/D4TB02103G⟩
Article dans une revue hal-04863058 v1
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Self-assembled porphyrin–peptide cages for photodynamic therapy

Chandramouli Ghosh , Lamiaa Ali , Yannick Bessin , Sébastien Clément , Sébastien Richeter et al.
Organic & Biomolecular Chemistry, 2024, 22 (7), pp.1484-1494. ⟨10.1039/d3ob01887c⟩
Article dans une revue hal-04560453 v1
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Amphiphilic dynamic covalent polymer vectors of siRNA

José García Coll , Pauline Trousselier , Sachin Dattram Pawar , Yannick Bessin , Laure Lichon et al.
Chemical Science, 2024, 16 (5), pp.2413-2419. ⟨10.1039/D4SC07668K⟩
Article dans une revue hal-05048015 v1

Antioxidant, antiproliferative, anti-inflammatory, and enzyme inhibition potentials of Ficus carica wood bark and related bioactive phenolic metabolites

Sonia Yahiaoui , Djamel-Edine Kati , Makhlouf Chaalal , Lamiaa Mohamed Ahmed Ali , Khaled El Cheikh et al.
Wood Science and Technology, 2024, 58 (3), pp.1051-1075. ⟨10.1007/s00226-024-01549-y⟩
Article dans une revue hal-04818306 v1
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Synthesis, photophysical characterization, and integration of two-photon-responsive fluorophores in mesoporous organosilica nanoparticles for biological imaging use

Nicolas Bondon , Nicolas Richy , Lamiaa M.A. Ali , Denis Durand , Magali Gary-Bobo et al.
Tetrahedron, 2023, 144, pp.133577. ⟨10.1016/j.tet.2023.133577⟩
Article dans une revue hal-04186939 v1
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Two‐photon Light Trigger Sirna Transfection of Cancer Cells Using Non‐Toxic Porous Silicon Nanoparticles

Arnaud Chaix , Eduardo Cueto-Díaz , Sofia Dominguez-Gil , Chantelle Spiteri , Laure Lichon et al.
Advanced Healthcare Materials, 2023, ⟨10.1002/adhm.202301052⟩
Article dans une revue hal-04179256 v1

In Vitro Anti-inflammatory Activity of Three Inula Species Essential Oils in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages

Nawres Gharred , Lamiaa Mohamed Ahmed Ali , Nadir Bettache , Sonia Dridi-Dhaouadi , Alain Morère et al.
Chemistry Africa, 2023, 6 (4), pp.1933-1942. ⟨10.1007/s42250-023-00641-3⟩
Article dans une revue hal-04612722 v1
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Wound Dressings Based on Sodium Alginate–Polyvinyl Alcohol–Moringa oleifera Extracts

Samir Kamel , Sawsan Dacrory , Peter Hesemann , Nadir Bettache , Lamiaa M A Ali et al.
Pharmaceutics, 2023, 15 (4), pp.1270. ⟨10.3390/pharmaceutics15041270⟩
Article dans une revue hal-04090038 v1
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Periodic mesoporous ionosilica nanoparticles for dual cancer therapy: Two-photon excitation siRNA gene silencing in cells and photodynamic therapy in zebrafish embryos

Braham Mezghrani , Lamiaa M.A. Ali , Nicolas Cubedo , Mireille Rossel , Peter Hesemann et al.
International Journal of Pharmaceutics, 2023, 641, pp.123083. ⟨10.1016/j.ijpharm.2023.123083⟩
Article dans une revue hal-04121650 v1
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Periodic Mesoporous Ionosilica Nanoparticles for BODIPY Delivery and Photochemical Internalization of siRNA

Braham Mezghrani , Lamiaa Ali , Sara Jakimoska , Frédérique Cunin , Peter Hesemann et al.
ChemPlusChem, 2023, 88 (3), pp.e202300021. ⟨10.1002/cplu.202300021⟩
Article dans une revue hal-04062152 v1
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A triazolium‐anchored self‐immolative linker enables self‐assembly‐driven siRNA binding and esterase‐induced release

Selina Hollstein , Lamiaa Ali , Maëva Coste , Julian Vogel , Nadir Bettache et al.
Chemistry - A European Journal, 2023, 29 (8), pp.e202203311. ⟨10.1002/chem.202203311⟩
Article dans une revue hal-03854124 v1
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Photosensitivity of Different Nanodiamond–PMO Nanoparticles in Two-Photon-Excited Photodynamic Therapy

Nicolas Bondon , Denis Durand , Kamel Hadj-Kaddour , Lamiaa M A Ali , Rabah Boukherroub et al.
Life, 2022, This article belongs to the Special Issue Photodynamic Diagnosis and Therapy, 12 (12), pp.2044. ⟨10.3390/life12122044⟩
Article dans une revue hal-03896140 v2

Phytochemical profile and biological effects of essential oils from three Inula species grown in Tunisia

Nawres Gharred , Lamiaa Ali , Nadir Bettache , Alain Morere , Chantal Menut et al.
Journal of Essential Oil Research, 2022, 34 (5), pp.405-415. ⟨10.1080/10412905.2022.2075479⟩
Article dans une revue hal-03854083 v1
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Structure‐Activity Relationships in Nucleic‐Acid‐Templated Vectors Based on Peptidic Dynamic Covalent Polymers

Dan-Dan Su , Lamiaa Ali , Maëva Coste , Nabila Laroui , Yannick Bessin et al.
Chemistry - A European Journal, 2022, ⟨10.1002/chem.202202921⟩
Article dans une revue hal-03854114 v1

Assessment of antioxidant, antiproliferative, anti-inflammatory, and enzyme inhibition activities and UPLC-MS phenolic determination of Ficus carica latex

Sonia Yahiaoui , Djamel-Edine Kati , Lamiaa M.A. Ali , Khaled El Cheikh , Alain Morère et al.
Industrial Crops and Products, 2022, 178, pp.114629. ⟨10.1016/j.indcrop.2022.114629⟩
Article dans une revue hal-03854081 v1
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Vegetable oil-based hybrid microparticles as a green and biocompatible system for subcutaneous drug delivery

Koceïla Doufène , Ilaria Basile , Aurélien Lebrun , Nelly Pirot , Aurélie Escande et al.
International Journal of Pharmaceutics, 2021, 592, pp.120070. ⟨10.1016/j.ijpharm.2020.120070⟩
Article dans une revue hal-03110144 v1
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Cell‐selective siRNA delivery using glycosylated dynamic covalent polymers self‐assembled in situ by RNA‐templating

Nabila Laroui , Maëva Coste , Dandan Su , Lamiaa Ali , Yannick Bessin et al.
Angewandte Chemie International Edition, 2021, 60 (11), pp.5783-5787. ⟨10.1002/anie.202014066⟩
Article dans une revue hal-03113520 v1
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Periodic Mesoporous Ionosilica Nanoparticles for Green Light Photodynamic Therapy and Photochemical Internalization of siRNA

Braham Mezghrani , Lamiaa M A Ali , Sébastien Richeter , Jean-Olivier Durand , Peter Hesemann et al.
ACS Applied Materials & Interfaces, 2021, 13 (25), pp.29325-29339. ⟨10.1021/acsami.1c05848⟩
Article dans une revue hal-03279491 v1
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Modified Indulines: From Dyestuffs to in vivo Theranostic Agents

Zhongrui Chen , Simon Pascal , Morgane Daurat , Laure Lichon , Christophe Nguyen et al.
ACS Applied Materials & Interfaces, 2021, ⟨10.1021/acsami.1c05933⟩
Article dans une revue hal-03269501 v1
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Wastewater to Ecological Dyeing Process and Bioactive Compounds Resources: Case Study of Dittrichia graveolens Hydrodistillation Aqueous Residue

Nawres Gharred , Noureddine Baaka , Nadir Bettache , Assia Hamdi , Amal Dbeibia et al.
Waste and Biomass Valorization, 2021, 12 (9), pp.5065-5077. ⟨10.1007/s12649-021-01375-4⟩
Article dans une revue hal-04578734 v1
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A rational study of the influence of Mn(2+)-insertion in Prussian blue nanoparticles on their photothermal properties

Maëlle Cahu , Lamiaa Mohamed Ahmed Ali , Saad Sene , Jérôme Long , Franck Camerel et al.
Journal of materials chemistry‎ B, 2021, 9 (47), pp.9670-9683. ⟨10.1039/d1tb00888a⟩
Article dans une revue hal-03414675 v1
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Cytotoxic activities of Psidium guajava and Mangifera indica plant extracts on human healthy skin fibroblasts and human hepatocellular carcinoma

Gislaine Aurelie Kemegne , Nadir Bettache , Maximilienne Ascension Nyegue , François-Xavier Etoa , Chantal Menut
Issues in Biological Sciences and Pharmaceutical Research, 2020, 8 (4), pp.58-64. ⟨10.15739/ibspr.20.007⟩
Article dans une revue hal-03114647 v1

Improvement of Cell Penetrating Peptide for Efficient siRNA Targeting of Tumor Xenografts in Zebrafish Embryos

Nabila Laroui , Nicolas Cubedo , Anne-Marinette Cao , Mireille Rossel , Nadir Bettache
Advanced Therapeutics, 2020, 3 (2), pp.1900204. ⟨10.1002/adtp.201900204⟩
Article dans une revue hal-02460044 v1
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Sequential delivery of synergistic drugs by silica nanocarriers for enhanced tumour treatment

Albane Birault , Simon Giret , Christophe Théron , Audrey Gallud , Afitz da Silva et al.
Journal of materials chemistry‎ B, 2020, 8 (7), pp.1472-1480. ⟨10.1039/c9tb02225b⟩
Article dans une revue hal-03096456 v1

Pyclen-Based Ln(III) Complexes as Highly Luminescent Bioprobes for In Vitro and In Vivo One- and Two-Photon Bioimaging Applications

Nadège Hamon , Amandine Roux , Maryline Beyler , Jean-Christophe Mulatier , Chantal Andraud et al.
Journal of the American Chemical Society, 2020, ⟨10.1021/jacs.0c03496⟩
Article dans une revue hal-02616978 v1
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Degradable double hydrophilic block copolymers and tripartite polyionic complex micelles thereof for small interfering ribonucleic acids (siRNA) delivery

Ayman El Jundi , Marie Morille , Nadir Bettache , Audrey Bethry , Jade Berthelot et al.
Journal of Colloid and Interface Science, 2020, 580, pp.449-459. ⟨10.1016/j.jcis.2020.07.057⟩
Article dans une revue hal-03025049 v1
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Hydrocarbon-Stapled Peptide Based-Nanoparticles for siRNA Delivery

Matthieu Simon , Nabila Laroui , Marianne Heyraud , Guillaume Laconde , Lamiaa Mohamed Ahmed Ali et al.
Nanomaterials, 2020, 10 (12), pp.2334. ⟨10.3390/nano10122334⟩
Article dans une revue hal-03053993 v1

Organosilica Nanoparticles for Gemcitabine Monophosphate Delivery in Cancer Cells

Morgane Daurat , Saher Rahmani , Roza Bouchal , Alia Akrout , Jelena Budimir et al.
ChemNanoMat, 2019, 5 (7), pp.888-896. ⟨10.1002/cnma.201900202⟩
Article dans une revue hal-02347901 v1
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Porphyrin‐based bridged silsesquioxane nanoparticles for targeted two‐photon photodynamic therapy of zebrafish xenografted with human tumor

Soraya Dib , Dina Aggad , Chiara Mauriello Jimenez , Ahmed Lakrafi , Guillaume Héry et al.
Cancer reports, 2019, 2 (5), pp.e1186. ⟨10.1002/cnr2.1186⟩
Article dans une revue hal-02355962 v1

Front Cover: Organosilica Nanoparticles for Gemcitabine Monophosphate Delivery in Cancer Cells (ChemNanoMat 7/2019)

Morgane Daurat , Saher Rahmani , Roza Bouchal , Alia Akrout , Jelena Budimir et al.
ChemNanoMat, 2019, 5 (7), pp.858-858. ⟨10.1002/cnma.201900267⟩
Article dans une revue hal-02989376 v1
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The Syk Kinase Promotes Mammary Epithelial Integrity and Inhibits Breast Cancer Invasion by Stabilizing the E-Cadherin/Catenin Complex

Toufic Kassouf , Romain Maxime Larive , Anne Morel , Serge Urbach , Nadir Bettache et al.
Cancers, 2019, 11 (12), pp.1974. ⟨10.3390/cancers11121974⟩
Article dans une revue hal-02401110 v1
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Combination of photodynamic therapy and gene silencing achieved through the hierarchical self-assembly of porphyrin-siRNA complexes

Nabila Laroui , Maëva Coste , Laure Lichon , Yannick Bessin , Magali Gary-Bobo et al.
International Journal of Pharmaceutics, 2019, 569, pp.118585. ⟨10.1016/j.ijpharm.2019.118585⟩
Article dans une revue hal-02322136 v1
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Biomolecular dynamic covalent polymers for DNA complexation and siRNA delivery

Camille Bouillon , Yannick Bessin , Florian Poncet , Magali Gary-Bobo , Pascal Dumy et al.
Journal of materials chemistry‎ B, 2018, 6 (44), pp.7239-7246. ⟨10.1039/C8TB01278D⟩
Article dans une revue hal-01944488 v1

Porous Porphyrin-Based Organosilica Nanoparticles for NIR Two-Photon Photodynamic Therapy and Gene Delivery in Zebrafish

Chiara Mauriello Jimenez , Dina Aggad , Jonas Croissant , Karen Tresfield , Danielle Laurencin et al.
Advanced Functional Materials, 2018, 28 (21), pp.1800235. ⟨10.1002/adfm.201800235⟩
Article dans une revue hal-01973302 v1

Indoloazepinone-Constrained Oligomers as Cell-Penetrating and Blood-Brain-Barrier-Permeating Compounds

Olivier van Der Poorten , Baptiste Legrand , Lubomir Vezenkov , Júlia García-Pindado , Nadir Bettache et al.
ChemBioChem, 2018, 19 (7), pp.696-705. ⟨10.1002/cbic.201700678⟩
Article dans une revue hal-03564881 v1

Indoloazepinone-Containing Oligomers as Cell-Penetrating (Non)Peptides: Synthesis, Structuration and Internalization

Olivier van Der Poorten , Baptiste Legrand , Lubomir Vezenkov , Jean Martinez , Nadir Bettache et al.
Journal of Peptide Science, 2018, 22 (S2), pp.S117. ⟨10.1002/psc.2950⟩
Article dans une revue hal-03576982 v1

Ribbon-like Foldamers for Cellular Uptake and Drug Delivery

Lubomir L. Vezenkov , Vincent Martin , Nadir Bettache , Matthieu Simon , Alexandre Messerschmitt et al.
ChemBioChem, 2017, 18 (21), pp.2110-2114. ⟨10.1002/cbic.201700455⟩
Article dans une revue hal-01944639 v1
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20-nm-sized mesoporous silica nanoparticles with porphyrin photosensitizers for in vitro photodynamic therapy

Chiara Mauriello Jimenez , Yolanda Galàn Rubio , Valentin Saunier , David Warther , Vanja Stojanovic et al.
Journal of Sol-Gel Science and Technology, 2016, 79 (3), pp.447-456. ⟨10.1007/s10971-016-3991-6⟩
Article dans une revue hal-01569372 v1

Structure-Activity Relationships of JMV4463, a Vectorized Cathepsin D Inhibitor with Antiproliferative Properties: The Unique Role of the AMPA-Based Vector

Lubomir Vezenkov , Clément Sanchez , Virginie Bellet , Vincent Martin , Marie Maynadier et al.
ChemMedChem, 2016, 11 (3), pp.302-308. ⟨10.1002/cmdc.201500457⟩
Article dans une revue istex hal-02388735 v1
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Multivalent DNA recognition by self-assembled clusters: deciphering structural effects by fragments screening and evaluation as siRNA vectors

Eline Bartolami , Yannick Bessin , Nadir Bettache , Magali Gary-Bobo , Marcel Garcia et al.
Organic & Biomolecular Chemistry, 2015, 13 (36), pp.9427 - 9438. ⟨10.1039/c5ob01404b⟩
Article dans une revue hal-03116768 v1

Abstract 1978: The tyrosine kinase Syk plays a role in the maintenance of intercellular adhesive junctions in human breast cancer cells

Toufic Kassouf , Philippe Montcourrier , Romain Larive , Nadir Bettache , Anne Morel et al.
Cancer Research, 2014, 74 (19S), pp.1978-1978. ⟨10.1158/1538-7445.AM2014-1978⟩
Article dans une revue hal-03575279 v1
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Pro-cathepsin D interacts with the extracellular domain of the {beta} chain of LRP1 and promotes LRP1-dependent fibroblast outgrowth.

Mélanie Beaujouin , Christine Prébois , Danielle Derocq , Valérie Laurent-Matha , Olivier Masson et al.
Journal of Cell Science, 2010, 123 (19), pp.3336-3346. ⟨10.1242/jcs.070938⟩
Article dans une revue inserm-00518213 v1

The gelsolin:calponin complex nucleates actin filaments with distinct morphologies.

Imen Ferjani , Abdellatif Fattoum , Nadir Bettache , Bastien Seantier , Pierre-Emmanuel Milhiet et al.
Biochemical and Biophysical Research Communications, 2010, 392 (2), pp.118-23. ⟨10.1016/j.bbrc.2009.12.103⟩
Article dans une revue istex hal-00491991 v1

Cell membrane extensions, generated by mechanical constraint, are associated with a sustained lipid raft patching and an increased cell signaling.

Romain M Larive , Laurent Baisamy , Serge Urbach , Peter Coopman , Nadir Bettache
Biochimica et Biophysica Acta:Biomembranes, 2010, 1798 (3), pp.389-400. ⟨10.1016/j.bbamem.2009.11.016⟩
Article dans une revue hal-00492403 v1

Phosphoproteomic analysis of Syk kinase signaling in human cancer cells reveals its role in cell-cell adhesion.

R. M. Larive , Serge Urbach , Joël Poncet , Patrick Jouin , G. Mascré et al.
Oncogene, 2009, 28 (24), pp.2337-47. ⟨10.1038/onc.2009.99⟩
Article dans une revue hal-00400163 v1

Mechanical model of cytoskeleton structuration during cell adhesion and spreading

Bernard Maurin , Patrick Cañadas , Haimad Baudriller , Philippe Montcourrier , Nadir Bettache
Journal of Biomechanics, 2008, 41, pp.2036-2041. ⟨10.1016/j.jbiomech.2008.03.011⟩
Article dans une revue istex hal-00665316 v1
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Form-finding of complex tensegrity structures: application to cell cytoskeleton modelling

Haimad Baudriller , Bernard Maurin , Patrick Cañadas , Philippe Montcourrier , Andrea Parmeggiani et al.
Comptes Rendus Mécanique, 2006, 334, pp.662-668. ⟨10.1016/j.crme.2006.08.004⟩
Article dans une revue istex hal-00559870 v1

Gelsolin binds to polyphosphoinositide-free lipid vesicles and simultaneously to actin microfilaments

Jocelyn Méré , Anne Chahinian , Sutherland K. Maciver , Abdellatif Fattoum , Nadir Bettache et al.
Biochemical Journal, 2005, 386 (1), pp.47-56. ⟨10.1042/BJ20041054⟩
Article dans une revue hal-04122268 v1

HIV-1 Tat Enters T Cells Using Coated Pits before Translocating from Acidified Endosomes and Eliciting Biological Responses

Agnès Vendeville , Fabienne Rayne , Anne Bonhoure , Nadir Bettache , Philippe Montcourrier et al.
Molecular Biology of the Cell, 2004, 15 (5), pp.2347-2360. ⟨10.1091/mbc.e03-12-0921⟩
Article dans une revue hal-02137162 v1

Mechanical constraint imposed on plasma membrane through transverse phospholipid imbalance induces reversible actin polymerization via phosphoinositide 3-kinase activation

Nadir Bettache , Laurent Baisamy , Stephen Baghdiguian , Bernard Payrastre , Paul Mangeat et al.
Journal of Cell Science, 2003, 116 (11), pp.2277-2284. ⟨10.1242/jcs.00424⟩
Article dans une revue hal-04122099 v1

Impaired redistribution of aminophospholipids with distinctive cell shape change during Ca 2+ -induced activation of platelets from a patient with Scott syndrome

Nadir Bettache , Patrick Gaffet , Nicolas Allegre , Lucien Maurin , Florence Toti et al.
British Journal of Haematology, 1998, 101 (1), pp.50-58. ⟨10.1046/j.1365-2141.1998.00658.x⟩
Article dans une revue hal-04122263 v1

Potency and kinetics of nitric oxide-mediated vascular smooth muscle relaxation determined with flash photolysis of ruthenium nitrosyl chlorides

T. Carter , N. Bettache , D. Ogden
British Journal of Pharmacology, 1997, 122 (6), pp.971-973. ⟨10.1038/sj.bjp.0701549⟩
Article dans une revue hal-04122064 v1

Transverse Redistribution of Phospholipids during Human Platelet Activation: Evidence for a Vectorial Outflux Specific to Aminophospholipids

Patrick Gaffet , Nadir Bettache , Alain Bienvenuee
Biochemistry, 1995, 34 (20), pp.6762-6769. ⟨10.1021/bi00020a022⟩
Article dans une revue istex hal-04122071 v1

Photolytic release of nitric oxide modulates NMDA receptor-mediated transmission but does not induce long-term potentiation at hippocampal synapses

K.P.S.J. Murphy , J.H. Williams , N. Bettache , T.V.P. Bliss
Neuropharmacology, 1994, 33 (11), pp.1375-1385. ⟨10.1016/0028-3908(94)90039-6⟩
Article dans une revue istex hal-04122083 v1

Specific cross-linking of the SH1 thiol of skeletal myosin subfragment 1 to F-actin and G-actin

Nadir Bettache , Raoul Bertrand , Ridha Kassab
Biochemistry, 1992, 31 (2), pp.389-395. ⟨10.1021/bi00117a012⟩
Article dans une revue istex hal-04122292 v1

Maleimidobenzoyl-G-actin: structural properties and interaction with skeletal myosin subfragment-1

Nadir Bettache , Raoul Bertrand , Ridha Kassab
Biochemistry, 1990, 29 (38), pp.9085-9091. ⟨10.1021/bi00490a028⟩
Article dans une revue istex hal-04122282 v1

Coupling of nonpolymerizable monomeric actin to the F-actin binding region of the myosin head.

Nadir Bettache , R Bertrand , R Kassab
Proceedings of the National Academy of Sciences of the United States of America, 1989, 86 (16), pp.6028-6032. ⟨10.1073/pnas.86.16.6028⟩
Article dans une revue hal-04122260 v1

Bioimaging and two-photon photodynamic therapy with innovative multifunctional organosilica nanoparticles

Clarence Charnay , Nicolas Bondon , Lamiaa M.A. Ali , Christophe Nguyen , Jean-Olivier Durand et al.
12th International Mesostructured Materials Symposium (IMMS12), Jul 2024, MONTPELLIER, France
Communication dans un congrès hal-04708972 v1

Two-photon responsive fluorophore-porphyrin biodegradable PMO nanoparticles for FRET-enhanced PDT and antibiotic encapsulation

Nicolas Bondon , Clement Charlot , Alexandre Barras , Christophe Nguyen , Lamiaa Ali et al.
4th PDT/PDD Symposium, Oct 2022, Nancy, France. pp.103391, ⟨10.1016/j.pdpdt.2023.103391⟩
Communication dans un congrès hal-04257900 v1

Multi-lactamization reaction for the conception of foldamers and cell penetrating vectors

Lubomir Vezenkov , Alexandre Messerschmitt , Baptiste Legrand , Vincent Martin , Nadir Bettache et al.
Proceedings of the 2nd International Multidisciplinary event in Chemistry Between Balard Institut and K.N. Toosi University, Jan 2022, Teheran-Montpellier (Webinaire), France
Communication dans un congrès hal-04851702 v1
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Numerical model of the cytoskeleton structuration during cell spreading

Patrick Cañadas , Bernard Maurin , Haimad Baudriller , Philippe Montcourrier , Nadir Bettache
16th Congress ESB, Jul 2008, Lucerne, Switzerland. pp.Cd-Rom
Communication dans un congrès hal-00582903 v1

Form-finding of the cytoskeleton structuration during cell adhesion

Patrick Cañadas , Bernard Maurin , Haimad Baudriller , P. Montcourrier , Nadir Bettache
2nd European Meeting on Cell Mechanics (CellMech-2007), 2007, Barcelona, Spain
Communication dans un congrès hal-00582935 v1