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Nathalie Poupin

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Avoiding the Misuse of Pathway Analysis Tools in Environmental Metabolomics

Cecilia Wieder , Jacob Bundy , Clément Frainay , Nathalie Poupin , Pablo Rodríguez-Mier et al.
Environmental Science and Technology, inPress, ⟨10.1021/acs.est.2c05588⟩
Journal articles hal-03799270v1

Despite similar clinical features metabolomics reveals distinct signatures in insulin resistant and progressively obese minipigs

Imene Bousahba , Jérémie David , Florence A Castelli , Céline Chollet , Sadia Ouzia et al.
Journal of Physiology and Biochemistry, 2022, ⟨10.1007/s13105-022-00940-2⟩
Journal articles hal-03941308v1
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How Does Your Body Deal With Fast-Food Meals?

Nathalie Poupin , Sergio Polakof
Frontiers for Young Minds, 2022, 10, ⟨10.3389/frym.2022.707736⟩
Journal articles hal-03805014v1

SOC-II-03 Zebrafish as a model for chemical induced adipogenesis and related metabolic diseases

M. den Broeder , N. Habreaken , H. Farnezi , J. Massart , M. Stingl et al.
Toxicology Letters, 2022, 368, pp.S32. ⟨10.1016/j.toxlet.2022.07.106⟩
Journal articles hal-03811311v1
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Multiplatform metabolomics for an integrative exploration of metabolic syndrome in older men

Blandine Comte , Stéphanie Monnerie , Marion Brandolini-Bunlon , Cécile Canlet , Florence Castelli et al.
EBioMedicine, 2021, 69, ⟨10.1016/j.ebiom.2021.103440⟩
Journal articles hal-03283772v1
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Pathway analysis in metabolomics: Recommendations for the use of over-representation analysis

Cecilia Wieder , Clément Frainay , Nathalie Poupin , Pablo Rodríguez-Mier , Florence Vinson et al.
PLoS Computational Biology, 2021, 17 (9), ⟨10.1371/journal.pcbi.1009105⟩
Journal articles hal-03344682v1
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Transgenerational metabolomic fingerprints in mice ancestrally exposed to the obesogen TBT

Raquel Chamorro-García , Nathalie Poupin , Marie A Tremblay-Franco , Cécile Canlet , Riann Egusquiza et al.
Environment International, 2021, 157, ⟨10.1016/j.envint.2021.106822⟩
Journal articles hal-03335779v1
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DEXOM: Diversity-based enumeration of optimal context-specific metabolic networks

Pablo Rodríguez-Mier , Nathalie Poupin , Carlo de Blasio , Laurent Le Cam , Fabien Jourdan et al.
PLoS Computational Biology, 2021, 17 (2), ⟨10.1371/journal.pcbi.1008730⟩
Journal articles hal-03154775v1
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Mitochondrial metabolism supports resistance to IDH mutant inhibitors in acute myeloid leukemia

Lucille Stuani , Marie Sabatier , Estelle Saland , Guillaume Cognet , Nathalie Poupin et al.
Journal of Experimental Medicine, 2021, 218 (5), pp.e20200924. ⟨10.1084/jem.20200924⟩
Journal articles hal-03563454v1
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Postprandial NMR-Based Metabolic Exchanges Reflect Impaired Phenotypic Flexibility across Splanchnic Organs in the Obese Yucatan Mini-Pig

Marie A Tremblay-Franco , Nathalie Poupin , Aurélien Amiel , Cécile Canlet , Didier Remond et al.
Nutrients, 2020, 12 (8), pp.2442. ⟨10.3390/nu12082442⟩
Journal articles hal-02927174v1
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An Optimized Dual Extraction Method for the Simultaneous and Accurate Analysis of Polar Metabolites and Lipids Carried out on Single Biological Samples

Joran Villaret-Cazadamont , Nathalie Poupin , Anthony Tournadre , Aurélie Batut , Lara Gales et al.
Metabolites, 2020, 10 (9), pp.338. ⟨10.3390/metabo10090338⟩
Journal articles hal-02927122v1
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An Integrated Analysis of miRNA and Gene Expression Changes in Response to an Obesogenic Diet to Explore the Impact of Transgenerational Supplementation with Omega 3 Fatty Acids

Karla Fabiola Corral-Jara , Laura Cantini , Nathalie Poupin , Tao Ye , Jean-Paul Rigaudière et al.
Nutrients, 2020, 12 (12), pp.3864. ⟨10.3390/nu12123864⟩
Journal articles hal-03100700v1

Improving lipid mapping in Genome Scale Metabolic Networks using ontologies

Nathalie Poupin , Florence Vinson , Arthur Moreau , Aurélie Batut , Maxime Chazalviel et al.
Metabolomics, 2020, 16 (4), ⟨10.1007/s11306-020-01663-5⟩
Journal articles hal-02935172v1
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Addendum: An Optimised Dual Extraction Method for the Simultaneous and Accurate Analysis of Polar Metabolites and Lipids Carried out on Single Biological Samples. Metabolites 2020, 10, 338

Joran Villaret-Cazadamont , Nathalie Poupin , Anthony Tournadre , Aurélie Batut , Lara Gales et al.
Metabolites, 2020, 10 (12), ⟨10.3390/metabo10120490⟩
Journal articles hal-03109907v1
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Arterio-venous metabolomics exploration reveals major changes across liver and intestine in the obese Yucatan minipig

Nathalie Poupin , Marie A Tremblay-Franco , Aurélien Amiel , Cécile Canlet , Didier Remond et al.
Scientific Reports, 2019, 9 (1), ⟨10.1038/s41598-019-48997-2⟩
Journal articles hal-02282295v1
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Large-Scale Modeling Approach Reveals Functional Metabolic Shifts during Hepatic Differentiation

Nathalie Poupin , Anne Corlu , Nicolas J. Cabaton , Hélène Dubois-Pot-Schneider , Cécile Canlet et al.
Journal of Proteome Research, 2019, 18 (1), pp.204-216. ⟨10.1021/acs.jproteome.8b00524⟩
Journal articles hal-01937261v1
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An untargeted metabolomics approach to explore the metabolic modulation of HepG2 cells exposed to low doses of bisphenol A and 17β-estradiol 2

Nicolas J. Cabaton , Nathalie Poupin , Cécile Canlet , Marie A Tremblay-Franco , Marc Audebert et al.
Frontiers in Endocrinology, 2018, 9, ⟨10.3389/fendo.2018.00571⟩
Journal articles hal-02618654v1

Early changes in tissue amino acid metabolism and nutrient routing in rats fed a high-fat diet: evidence from natural isotope abundances of nitrogen and carbon in tissue proteins

Olivier Mantha , Sergio Polakof , Jean-François Huneau , François Mariotti , Nathalie Poupin et al.
British Journal of Nutrition, 2018, 119 (9), pp.981-991. ⟨10.1017/S0007114518000326⟩
Journal articles hal-01761202v1

Integrated transcriptomics and metabolomics reveal signatures of lipid metabolism dysregulation in HepaRG liver cells exposed to PCB 126

Robin Mesnage , Martina Biserni , Sucharitha Balu , Clément Frainay , Nathalie Poupin et al.
Archives of Toxicology, 2018, 92 (8), pp.2533-2547. ⟨10.1007/s00204-018-2235-7⟩
Journal articles hal-02621552v1
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MetExploreViz: web component for interactive metabolic network visualization

Maxime Chazalviel , Clément Frainay , Nathalie Poupin , Florence Vinson , Benjamin Merlet et al.
Bioinformatics, 2018, 34 (2), pp.312-313. ⟨10.1093/bioinformatics/btx588⟩
Journal articles hal-02621786v1
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MetExplore: collaborative edition and exploration of metabolic networks

Ludovic Cottret , Clément Frainay , Maxime Chazalviel , Floréal Cabanettes , Yoann Gloaguen et al.
Nucleic Acids Research, 2018, 46 (W1), 8 p. ⟨10.1093/nar/gky301⟩
Journal articles hal-01886470v1
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A computational solution to automatically map metabolite libraries in the context of genome scale metabolic networks

Benjamin Merlet , Nils Paulhe , Florence Vinson , Clément Frainay , Maxime Chazalviel et al.
Frontiers in Molecular Biosciences, 2016, 3, ⟨10.3389/fmolb.2016.00002⟩
Journal articles hal-02631089v1
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Natural Isotopic Signatures of Variations in Body Nitrogen Fluxes: A Compartmental Model Analysis

Nathalie Poupin , François Mariotti , Jean-François Huneau , Dominique Hermier , Hélène Fouillet et al.
PLoS Computational Biology, 2014, 10 (10), ⟨10.1371/journal.pcbi.1003865⟩
Journal articles hal-01186909v1

Effects of dark chocolate and cocoa consumption on endothelial function and arterial stiffness in overweight adults

Sheila G. West , Molly D. Mcintyre , Matthew J. Piotrowski , Nathalie Poupin , Debra L. Miller et al.
British Journal of Nutrition, 2014, 111 (4), pp.653-661. ⟨10.1017/S0007114513002912⟩
Journal articles hal-02638645v1
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Isotopic and modeling investigation of long-term protein turnover in rat tissues

Nathalie Poupin , Jean-François Huneau , François Mariotti , Daniel D. Tomé , Cecile C. Bos et al.
AJP - Regulatory, Integrative and Comparative Physiology, 2013, 304 (3), pp.R218 - R231. ⟨10.1152/ajpregu.00310.2012⟩
Journal articles hal-01001592v1

Impact of the diet on net endogenous acid production and acid–base balance

Nathalie Poupin , Juliane Calvez , Camille Lassale , Caroline Chesneau , Daniel Tomé et al.
Clinical Nutrition, 2012, 31 (3), pp.313 - 321. ⟨10.1016/j.clnu.2012.01.006⟩
Journal articles hal-01519016v1

Protein intake, calcium balance and health consequences

J Calvez , Nathalie Poupin , C Chesneau , C Lassale , D Tomé et al.
European Journal of Clinical Nutrition, 2012, 66 (3), pp.281 - 295. ⟨10.1038/ejcn.2011.196⟩
Journal articles hal-01519022v1
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The nature of the dietary protein impacts the tissue-to-diet N-15 discrimination factors in laboratory rats

Nathalie Poupin , Cecile Bos , François Mariotti , Jean-François Huneau , Daniel Tomé et al.
PLoS ONE, 2011, 6 (11), ⟨10.1371/journal.pone.0028046⟩
Journal articles hal-01186796v1
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Modelling the muscle metabolic response in anabolic and catabolic states using arterio-venous blood metabolomics profiles

Nathalie Poupin , Florence A Castelli , Emeline Chu-Van , Didier Remond , Dominique Dardevet et al.
8. Conference on Constraint-Based reconstruction and Analysis (COBRA 2022), Sep 2022, Galway, Ireland
Conference papers hal-03807737v1
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SAMBA, a recommendation system for biomarker discovery using metabolic networks

Juliette Cooke , Nathalie Poupin , Maxime Delmas , Clément Frainay , Florence Vinson et al.
8th Conference on Constraint-Based reconstruction and Analysis (COBRA 2022), Sep 2022, Galway, Ireland
Conference papers hal-03807772v1

Making Sense of lipidomics analyses using metabolic networks

Nathalie Poupin
Journées des Lypidomistes, Oct 2021, Bordeaux, France
Conference papers hal-03807711v1
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Metabolic adaptations in insulin resistant and dyslipidemic minipigs ranging from lean to morbid obesity.

Imene Bousahba , Jérémie David , Yves Guerin , Benoit Cohade , Didier Rémond et al.
18. Conference on Trans-Pyrenean Investigations in Obesity and Diabetes, Nov 2021, Clermont-Ferrand, France
Conference papers hal-03457729v1

Modelling intrahepatic metabolic rewiring during the onset of obesity using arterio-venous blood metabolomics profiles & constraint-based modelling approaches

Nathalie Poupin
Workshop Modélisation du Métabolisme, Nov 2021, Bordeaux, France
Conference papers hal-03807715v1
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Multi-omics phenotyping highlights organ-specific metabolic and inflammatory shifts associated with differential plant and animal protein intake in high fat fed rats

Gaïa Lépine , Hélène Fouillet , Marie A Tremblay-Franco , Didier Remond , Nathalie Poupin et al.
eNuGOweek 2021, Sep 2021, Online, France
Conference papers hal-03338806v1
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Modelling intrahepatic metabolic rewiring during the onset of obesity using arterio- venous blood metabolomics profiles

Nathalie Poupin , Marie A Tremblay-Franco , Cécile Canlet , Aurélien Amiel , Didier Rémond et al.
European RFMF Metabomeeting 2020, Jan 2020, Toulouse, France
Conference papers hal-02948334v1
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Insights from metabolomic and molecular signatures to detect, in a blood sample, muscle anabolic resistance associated with catabolic situation. Case model of glucocorticoids effect in mini-pigs

Sergio Polakof , Marie A Tremblay-Franco , Nathalie Poupin , Florence Castelli , Jérémie David et al.
Fifth International Congress of Translational Research in Human Nutrition (ICTRHN), Jun 2019, Clermont-Ferrand, France
Conference papers hal-02154641v1

Analysis of OMICS data in the context of metabolic networks

Nathalie Poupin
Workshop "Analyse et interprétation des données en protéomique et métabolomique : points communs et spécificités", Mar 2018, Lyon, France
Conference papers hal-02948297v1
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Modélisation du réseau métabolique des cellules de Leucémies Aiguës Myéloïdes pour comprendre les différences métaboliques liées à la mutation sur IDH1

Laurent Fernando , Lucille Stuani , Tony Lionel Palama , Tony Kaoma , Jean-Emmanuel Sarry et al.
Congrès de Spectrométrie de Masse, Métabolomique et Fluxomique (SMMAP), Oct 2017, Marne-la-Vallée, France
Conference papers hal-02946080v1

Exploring metabolic modulations using genome-scale network modelling and omics data

Nathalie Poupin
Workshop "Metabolism in Systems Biology", Nov 2016, Lille, France
Conference papers hal-02948304v1

Modélisation sous contraintes du métabolisme : une approche globale pour l’étude des modulations métaboliques

Nathalie Poupin
1ères journées du club Métabo-Cancer GSO, Apr 2015, Toulouse, France
Conference papers hal-02792590v1

Les abondances isotopiques de l'azote comme marqueurs des adaptations métaboliques à la qualité de l'apport protéique : analyse et interprétation par modélisation chez le rat

Nathalie Poupin , François Mariotti , Jean-François Huneau , Dominique D. Hermier , Hélène Fouillet et al.
1er séminaire Abondances Isotopiques Naturelles en Nutrition et Santé, Jan 2014, Paris, France
Conference papers hal-01598849v1

Les signatures isotopiques des dérégulations du métabolisme protéino-énergétique lors du développement d'un syndrome métabolique chez le rat

Nathalie Poupin , Jean-François Huneau , François Mariotti , Dominique D. Hermier , Tristan Mary-Huard et al.
1er séminaire Abondances Isotopiques Naturelles en Nutrition et Santé, Jan 2014, Paris, France
Conference papers hal-01598850v1

d15N and d13C values in body pools are biomarkers of the protein-energy dysregulations of the metabolic syndrome onse

Nathalie Poupin , J.F. Huneau , Tristan Mary-Huard , J.P. Godin , D. Hermier et al.
GEOMED 1st workshop on biomedical application of geochemistry, Aug 2013, Gargonza, Italy
Conference papers hal-01562202v1

Les abondances isotopiques naturelles témoignent de modulations nutritionnelles et physiopathologiques du métabolisme azoté : analyse par modélisation compartimentale

Nathalie Poupin , François Mariotti , J.-F. Huneau , D. Hermier , Hélène Fouillet et al.
Journées francophones de Nutrition, Dec 2013, Bordeaux, France. pp.S29 - S30, ⟨10.1016/S0007-9960(13)70311-0⟩
Conference papers hal-01584713v1

Les abondances isotopiques naturelles signent l’initiation nutritionnelle du syndrome métabolique.

Nathalie Poupin , François Mariotti , Jean-François Huneau , Tristan Mary-Huard , Jean-Philippe Godin et al.
Journées Francophones de Nutrition, Dec 2012, Lyon, France
Conference papers hal-01592265v1

A new method for the multi-tissue estimation of protein turnover by compartmental analysis of the nitrogen isotope dynamics in rats fed a N-15-enriched diet

Nathalie Poupin , Jean-François Huneau , François Mariotti , Cecile Bos , Daniel Tomé et al.
Experimental Biology Meeting 2011, Apr 2011, Washington D.C., France
Conference papers hal-01186837v1

Characterization of human isogenic epithelial cell lines as a relevant tool to study colon carcinogenesis and interaction between genes and environment

Arnaud Tête , Liana C. Arnaud , Hélène Le Mentec , Isabelle Gallais , Nathalie Poupin et al.
Society of Toxicology Annual Meeting (SOT 2022), Mar 2022, San Diego, United States. , 3579, pp.P204
Conference poster hal-03637792v1
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Study Protocol: A 2-Month Cross-Over Controlled Feeding Trial Investigating the Effect of Animal and Plant Protein Intake on the Metabolome and Cardiometabolic Health

Gaïa Lépine , François Mariotti , Jean-François Huneau , Nathalie Poupin , Marie A Tremblay-Franco et al.
Nutrition Live Online 2021, Jun 2021, Inconnu, United States. Current Developments in Nutrition, 5 (Supplement_2), pp.1281, 2021, ⟨10.1093/cdn/nzab057_011⟩
Conference poster hal-03292189v1
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Improving prediction of essential genes using context-specific metabolic network ensembles

Pablo Rodríguez-Mier , Nathalie Poupin , Carlo de Blasio , Laurent Le Cam , Fabien Jourdan et al.
European RFMF Metabomeeting 2020, Jan 2020, Toulouse, France
Conference poster hal-02948371v1
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MetExplore: Omics data analysis in the context of metabolic networks

Maxime Chazalviel , Adrien Rohan , Nathalie Poupin , Florence Vinson , Clément Frainay et al.
European RFMF Metabomeeting 2020, Jan 2020, Toulouse, France.
Conference poster hal-02948391v1
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INPUT OF DEEP PHENOTYPING IN THE METABOLIC SYNDROME STRATIFICATION

Stéphanie Monnerie , Mélanie Pétéra , Cécile Canlet , Florence Castelli , Benoit Colsch et al.
European RFMF Metabomeeting 2020, Jan 2020, Toulouse, France. , 262 p., 2020, Oral and Poster Abstracts European RMF Metabomeeting 2020
Conference poster hal-02505908v1
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Fast-Quenching Standard Comparison of two sampling and extraction protocols to perform metabolomic studies on human adherent cells

Joran Villaret-Cazadamont , Noémie Butin , Jean-Francois Martin , Marie A Tremblay-Franco , Cécile Canlet et al.
European RFMF Metabomeeting 2020, Jan 2020, Toulouse, France
Conference poster hal-02948361v1

Study of the hepatic metabolic effects induced by PFOA exposure using a multiplatform metabolomics approach

Joran Villaret-Cazadamont , Noemie Butin , Cécile Canlet , Marie A Tremblay-Franco , Roselyne Gautier et al.
55. Congress of the European-Societies-of-Toxicology (EUROTOX) - Toxicology - Science Providing Solutions, Sep 2019, Helsinki, Finland. ELSEVIER IRELAND LTD, 2019, TOXICOLOGY LETTERS
Conference poster hal-02306108v1

Par rapport aux protéines de lait, un mélange de protéines de blé et de pois limite l’insulino-résistance et la lipogenèse de novo induites par un régime riche en lipides et saccharose

Sergio Polakof , Jean-François Huneau , Dominique Hermier , Didier Remond , Gaîa Lépine et al.
Journées Francophones de Nutrition, Nov 2019, Rennes, France. 2019, JFN 2019 Livre des résumés
Conference poster hal-02383599v1
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Impaired postprandial skeletal muscle metabolism in a minipig model of insulin resistance: insights from arteriovenous and biopsy-based metabolomics analyses

Marie A Tremblay-Franco , Nathalie Poupin , Florence Castelli , Jérémie David , Marianne Jarzaguet et al.
12. Journées Scientifiques du Réseau Francophone de Métabolomique et Fluxomique RFMF, May 2019, Clermont-Ferrand, France. 168 p., 2019, Livre des résumés
Conference poster hal-02285596v1
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Un mélange équilibré de protéines végétales permet une homéostasie protéique tissulaire normale grâce à l’activation de remaniements métaboliques des acides aminés

Hélène Fouillet , Didier Rémond , François Mariotti , Gaïa Lépine , Véronique Mathé et al.
Journées Francophones de Nutrition, Nov 2019, Rennes, France
Conference poster hal-02948410v1

Modelling hepatic metabolic changes during the onset of obesity using NMR metabolomics arterio-venous blood exploration in minipigs

Nathalie Poupin , Marie A Tremblay-Franco , Aurélien Amiel , Cécile Canlet , Didier Remond et al.
12. Journées Scientifiques du Réseau Francophone de Métabolomique et Fluxomique RFMF, May 2019, Clermont-Ferrand, France. 168 p., 2019, Livre des résumés
Conference poster hal-02162584v1
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Hepatic metabolomics and transcriptomics provide valuable insights on inflammatory and metabolic features in rats fed on a high fat diet but showing similar clinical phenotyping alterations

Sergio Polakof , Marie A Tremblay-Franco , Cécile Canlet , Jérémie David , Fabien Jourdan et al.
12. Journées Scientifiques du Réseau Francophone de Métabolomique et Fluxomique RFMF, May 2019, Clermont-Ferrand, France. 168 p., 2019, Livre des résumés
Conference poster hal-02162582v1

Modeling hepatic metabolic changes during the onset of obesity from metabolomics arterio-venous blood exploration in minipigs

Nathalie Poupin , Marie A Tremblay-Franco , Aurélien Amiel , Cécile Canlet , Didier Remond et al.
Copenhagen Bioscience Conference 2017: Where big-data gets translated into knowledge, May 2017, Copenhague, Netherlands. 2017, Bioscience Conference 2017
Conference poster hal-01606420v1
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Natural abundance of nitrogen isotopes in amino acids are biomarkers of the metabolic syndrome onset

Jean-François Huneau , Klaus-Jürgen Petzke , Nathalie Poupin , Tristan Mary-Huard , Olivier Mantha et al.
12th european nutrition conference, Oct 2015, Berlin, Germany. KARGER, 67, pp.1, 2015, Annals of Nutrition and Metabolism
Conference poster hal-01572322v1

Analysing human metabolic networks using metabolomics

Nathalie Poupin , Fabien Jourdan
Metabolomics as a Tool in Nutrition Research, Elsevier, pp.85-114, 2015, ⟨10.1016/B978-1-78242-084-2.00005-8⟩
Book sections hal-03318813v1

Human metabolic networks and metabolomics

Fabien Jourdan , Nathalie Poupin
Metabolomics as tool in nutrition research, Woodhead publishing Limited, 2014
Book sections hal-01187878v1