Nathalie Poupin

Documents

Publications

	Genome scale metabolic network modelling for metabolic profile predictions Juliette Cooke , Maxime Delmas , Cecilia Wieder , Pablo Rodríguez Mier , Clément Frainay PLoS Computational Biology, 2024, 20 (2), pp.e1011381. ⟨10.1371/journal.pcbi.1011381⟩ Journal articles hal-04596969v1
	PathIntegrate: Multivariate modelling approaches for pathway-based multi-omics data integration Cecilia Wieder , Juliette Cooke , Clement Frainay , Nathalie Poupin , Russell Bowler PLoS Computational Biology, 2024, 20 (3), pp.e1011814. ⟨10.1371/journal.pcbi.1011814⟩ Journal articles hal-04597222v1
	Weight of evidence evaluation of the metabolism disrupting effects of triphenyl phosphate using an expert knowledge elicitation approach Claire Beausoleil , Anne Thébault , Patrik Andersson , Nicolas Cabaton , Sibylle Ermler Toxicology and Applied Pharmacology, 2024, 489, pp.116995. ⟨10.1016/j.taap.2024.116995⟩ Journal articles anses-04629007v1
	A strategy to detect metabolic changes induced by exposure to chemicals from large sets of condition-specific metabolic models computed with enumeration techniques Louison Fresnais , Olivier Perin , Anne Riu , Romain Grall, , Alban Ott BMC Bioinformatics, 2024, 25 (1), pp.234. ⟨10.1186/s12859-024-05845-z⟩ Journal articles hal-04652792v1
	Challenges and perspectives for naming lipids in the context of lipidomics Michael Witting , Adnan Malik , Andrew Leach , Alan Bridge , Lucila Aimo Metabolomics, 2024, 20 (1), pp.15. ⟨10.1007/s11306-023-02075-x⟩ Journal articles hal-04596970v1
	Lipidomic Profiling of PFOA-Exposed Mouse Liver by Multi-Modal Mass Spectrometry Analysis Charlotte Stoffels , Tina Angerer , Hervé Robert , Nathalie Poupin , Laila Mselli-Lakhal Analytical Chemistry, 2023, 95 (16), pp.6568-6576. ⟨10.1021/acs.analchem.2c05470⟩ Journal articles hal-04102871v1
	Compared with Milk Protein, a Wheat and Pea Protein Blend Reduces High-Fat, High-Sucrose Induced Metabolic Dysregulations while Similarly Supporting Tissue Protein Anabolism in Rats Gaïa Lépine , Jean-François Huneau , Didier Remond , Véronique Mathé , Jérémie David Journal of Nutrition, 2023, 153 (3), pp.645-656. ⟨10.1016/j.tjnut.2022.12.029⟩ Journal articles hal-03940315v1
	Despite similar clinical features metabolomics reveals distinct signatures in insulin resistant and progressively obese minipigs Imene Bousahba , Jérémie David , Florence A Castelli , Céline Chollet , Sadia Ouzia Journal of Physiology and Biochemistry, 2023, 79 (2), pp.397-413. ⟨10.1007/s13105-022-00940-2⟩ Journal articles hal-03941308v1
	Avoiding the Misuse of Pathway Analysis Tools in Environmental Metabolomics Cecilia Wieder , Jacob Bundy , Clément Frainay , Nathalie Poupin , Pablo Rodríguez-Mier Environmental Science and Technology, inPress, ⟨10.1021/acs.est.2c05588⟩ Journal articles hal-03799270v1
	SOC-II-03 Zebrafish as a model for chemical induced adipogenesis and related metabolic diseases M. den Broeder , N. Habreaken , H. Farnezi , J. Massart , M. Stingl Toxicology Letters, 2022, 368, pp.S32. ⟨10.1016/j.toxlet.2022.07.106⟩ Journal articles hal-03811311v1
	How Does Your Body Deal With Fast-Food Meals? Nathalie Poupin , Sergio Polakof Frontiers for Young Minds, 2022, 10, ⟨10.3389/frym.2022.707736⟩ Journal articles hal-03805014v1
	Transgenerational metabolomic fingerprints in mice ancestrally exposed to the obesogen TBT Raquel Chamorro-García , Nathalie Poupin , Marie Tremblay-Franco , Cécile Canlet , Riann Egusquiza Environment International, 2021, 157, ⟨10.1016/j.envint.2021.106822⟩ Journal articles hal-03335779v1
	Mitochondrial metabolism supports resistance to IDH mutant inhibitors in acute myeloid leukemia Lucille Stuani , Marie Sabatier , Estelle Saland , Guillaume Cognet , Nathalie Poupin Journal of Experimental Medicine, 2021, 218 (5), pp.e20200924. ⟨10.1084/jem.20200924⟩ Journal articles hal-03563454v1
	DEXOM: Diversity-based enumeration of optimal context-specific metabolic networks Pablo Rodríguez-Mier , Nathalie Poupin , Carlo de Blasio , Laurent Le Cam , Fabien Jourdan PLoS Computational Biology, 2021, 17 (2), ⟨10.1371/journal.pcbi.1008730⟩ Journal articles hal-03154775v1
	Pathway analysis in metabolomics: Recommendations for the use of over-representation analysis Cecilia Wieder , Clément Frainay , Nathalie Poupin , Pablo Rodríguez-Mier , Florence Vinson PLoS Computational Biology, 2021, 17 (9), ⟨10.1371/journal.pcbi.1009105⟩ Journal articles hal-03344682v1
	Multiplatform metabolomics for an integrative exploration of metabolic syndrome in older men Blandine Comte , Stéphanie Monnerie , Marion Brandolini-Bunlon , Cécile Canlet , Florence Castelli EBioMedicine, 2021, 69, ⟨10.1016/j.ebiom.2021.103440⟩ Journal articles hal-03283772v1
	Improving lipid mapping in Genome Scale Metabolic Networks using ontologies Nathalie Poupin , Florence Vinson , Arthur Moreau , Aurélie Batut , Maxime Chazalviel Metabolomics, 2020, 16 (4), ⟨10.1007/s11306-020-01663-5⟩ Journal articles hal-02935172v1
	Postprandial NMR-Based Metabolic Exchanges Reflect Impaired Phenotypic Flexibility across Splanchnic Organs in the Obese Yucatan Mini-Pig Marie Tremblay-Franco , Nathalie Poupin , Aurélien Amiel , Cécile Canlet , Didier Remond Nutrients, 2020, 12 (8), pp.2442. ⟨10.3390/nu12082442⟩ Journal articles hal-02927174v1
	An Optimized Dual Extraction Method for the Simultaneous and Accurate Analysis of Polar Metabolites and Lipids Carried out on Single Biological Samples Joran Villaret-Cazadamont , Nathalie Poupin , Anthony Tournadre , Aurélie Batut , Lara Gales Metabolites, 2020, 10 (9), pp.338. ⟨10.3390/metabo10090338⟩ Journal articles hal-02927122v1
	Addendum: An Optimised Dual Extraction Method for the Simultaneous and Accurate Analysis of Polar Metabolites and Lipids Carried out on Single Biological Samples. Metabolites 2020, 10, 338 Joran Villaret-Cazadamont , Nathalie Poupin , Anthony Tournadre , Aurélie Batut , Lara Gales Metabolites, 2020, 10 (12), ⟨10.3390/metabo10120490⟩ Journal articles hal-03109907v1
	An Integrated Analysis of miRNA and Gene Expression Changes in Response to an Obesogenic Diet to Explore the Impact of Transgenerational Supplementation with Omega 3 Fatty Acids Karla Fabiola Corral-Jara , Laura Cantini , Nathalie Poupin , Tao Ye , Jean-Paul Rigaudière Nutrients, 2020, 12 (12), pp.3864. ⟨10.3390/nu12123864⟩ Journal articles hal-03100700v1
	Large-Scale Modeling Approach Reveals Functional Metabolic Shifts during Hepatic Differentiation Nathalie Poupin , Anne Corlu , Nicolas J. Cabaton , Hélène Dubois-Pot-Schneider , Cécile Canlet Journal of Proteome Research, 2019, 18 (1), pp.204-216. ⟨10.1021/acs.jproteome.8b00524⟩ Journal articles hal-01937261v1
	Arterio-venous metabolomics exploration reveals major changes across liver and intestine in the obese Yucatan minipig Nathalie Poupin , Marie Tremblay-Franco , Aurélien Amiel , Cécile Canlet , Didier Remond Scientific Reports, 2019, 9 (1), ⟨10.1038/s41598-019-48997-2⟩ Journal articles hal-02282295v1
	An untargeted metabolomics approach to explore the metabolic modulation of HepG2 cells exposed to low doses of bisphenol A and 17β-estradiol 2 Nicolas J. Cabaton , Nathalie Poupin , Cécile Canlet , Marie Tremblay-Franco , Marc Audebert Frontiers in Endocrinology, 2018, 9, ⟨10.3389/fendo.2018.00571⟩ Journal articles hal-02618654v1
	Early changes in tissue amino acid metabolism and nutrient routing in rats fed a high-fat diet: evidence from natural isotope abundances of nitrogen and carbon in tissue proteins Olivier Mantha , Sergio Polakof , Jean-François Huneau , François Mariotti , Nathalie Poupin British Journal of Nutrition, 2018, 119 (9), pp.981-991. ⟨10.1017/S0007114518000326⟩ Journal articles hal-01761202v1
	Integrated transcriptomics and metabolomics reveal signatures of lipid metabolism dysregulation in HepaRG liver cells exposed to PCB 126 Robin Mesnage , Martina Biserni , Sucharitha Balu , Clément Frainay , Nathalie Poupin Archives of Toxicology, 2018, 92 (8), pp.2533-2547. ⟨10.1007/s00204-018-2235-7⟩ Journal articles hal-02621552v1
	MetExploreViz: web component for interactive metabolic network visualization Maxime Chazalviel , Clément Frainay , Nathalie Poupin , Florence Vinson , Benjamin Merlet Bioinformatics, 2018, 34 (2), pp.312-313. ⟨10.1093/bioinformatics/btx588⟩ Journal articles hal-02621786v1
	MetExplore: collaborative edition and exploration of metabolic networks Ludovic Cottret , Clément Frainay , Maxime Chazalviel , Floréal Cabanettes , Yoann Gloaguen Nucleic Acids Research, 2018, 46 (W1), 8 p. ⟨10.1093/nar/gky301⟩ Journal articles hal-01886470v1
	A computational solution to automatically map metabolite libraries in the context of genome scale metabolic networks Benjamin Merlet , Nils Paulhe , Florence Vinson , Clément Frainay , Maxime Chazalviel Frontiers in Molecular Biosciences, 2016, 3, ⟨10.3389/fmolb.2016.00002⟩ Journal articles hal-02631089v1
	Effects of dark chocolate and cocoa consumption on endothelial function and arterial stiffness in overweight adults Sheila G. West , Molly D. Mcintyre , Matthew J. Piotrowski , Nathalie Poupin , Debra L. Miller British Journal of Nutrition, 2014, 111 (4), pp.653-661. ⟨10.1017/S0007114513002912⟩ Journal articles hal-02638645v1
	Natural Isotopic Signatures of Variations in Body Nitrogen Fluxes: A Compartmental Model Analysis Nathalie Poupin , François Mariotti , Jean-François Huneau , Dominique Hermier , Hélène Fouillet PLoS Computational Biology, 2014, 10 (10), ⟨10.1371/journal.pcbi.1003865⟩ Journal articles hal-01186909v1
	Isotopic and modeling investigation of long-term protein turnover in rat tissues Nathalie Poupin , Jean-François Huneau , François Mariotti , Daniel D. Tomé , Cecile C. Bos AJP - Regulatory, Integrative and Comparative Physiology, 2013, 304 (3), pp.R218 - R231. ⟨10.1152/ajpregu.00310.2012⟩ Journal articles hal-01001592v1
	Protein intake, calcium balance and health consequences J Calvez , Nathalie Poupin , C Chesneau , C Lassale , D Tomé European Journal of Clinical Nutrition, 2012, 66 (3), pp.281 - 295. ⟨10.1038/ejcn.2011.196⟩ Journal articles hal-01519022v1
	Impact of the diet on net endogenous acid production and acid–base balance Nathalie Poupin , Juliane Calvez , Camille Lassale , Caroline Chesneau , Daniel Tomé Clinical Nutrition, 2012, 31 (3), pp.313 - 321. ⟨10.1016/j.clnu.2012.01.006⟩ Journal articles hal-01519016v1
	The nature of the dietary protein impacts the tissue-to-diet N-15 discrimination factors in laboratory rats Nathalie Poupin , Cecile Bos , François Mariotti , Jean-François Huneau , Daniel Tomé PLoS ONE, 2011, 6 (11), ⟨10.1371/journal.pone.0028046⟩ Journal articles hal-01186796v1

	Exploration multi-omique et in silico des effets transgénérationels et sexe-spécifiques induits par le TBT, un composé obésogène, sur le métabolisme hépatique de la souris Nathalie Poupin , Fabien Jourdan , Raquel Chamorro-García , Toshi Shioda , Richard C Chang 15èmes journées scientifiques du Réseau Français de Métabolomique et Fluxomique (RFMF), May 2023, Perpignan, France Conference papers hal-04596856v1
	Exploring the impact of plant protein vs. animal protein-rich diets in men at cardiometabolic risk: insights from plasma metabolome signatures Gaïa Lépine , Marie Tremblay-Franco , François Mariotti , Jérémie David , Marion Courrent 3rd Nordic Metabolomics Conference, Oct 2023, Trondheim, Norway Conference papers hal-04354565v1
	Arteriovenous metabolomic approach reveals specific metabolite exchanges across organs and provides unique insights for understanding underlying metabolic perturbations in obese and insulin-resistant minipigs Imene Bousahba , Jérémie David , Florence Castelli , Céline Chollet , François Fenaille 15eme Journées Scienfitiques du Réseau Français de Métabolomique et Fluxomique, RFMF, May 2023, Perpignan, France Conference papers hal-04666938v1
	L’exploration des échanges inter-organes par métabolomique artérioveineuse offre une perspective unique pour comprendre les perturbations métaboliques sous-jacentes dans l’installation de l'obésité et de l'insulino-résistance chez les miniporcs Imene Bousahba , Jérémie David , Florence Castelli , Céline Chollet , François Fenaille Journées Francophones de Nutrition, SFN, Dec 2023, Marseille, France Conference papers hal-04667070v1
	SAMBA, a recommendation system for biomarker discovery using metabolic networks Juliette Cooke , Nathalie Poupin , Maxime Delmas , Clément Frainay , Florence Vinson 8th Conference on Constraint-Based reconstruction and Analysis (COBRA 2022), Sep 2022, Galway, Ireland Conference papers hal-03807772v1
	Modelling the muscle metabolic response in anabolic and catabolic states using arterio-venous blood metabolomics profiles Nathalie Poupin , Florence A Castelli , Emeline Chu-Van , Didier Remond , Dominique Dardevet 8. Conference on Constraint-Based reconstruction and Analysis (COBRA 2022), Sep 2022, Galway, Ireland Conference papers hal-03807737v1
	Making Sense of lipidomics analyses using metabolic networks Nathalie Poupin Journées des Lypidomistes, Oct 2021, Bordeaux, France Conference papers hal-03807711v1
	Multi-omics phenotyping highlights organ-specific metabolic and inflammatory shifts associated with differential plant and animal protein intake in high fat fed rats Gaïa Lépine , Hélène Fouillet , Marie Tremblay-Franco , Didier Remond , Nathalie Poupin eNuGOweek 2021, Sep 2021, Online, France Conference papers hal-03338806v1
	Modelling intrahepatic metabolic rewiring during the onset of obesity using arterio-venous blood metabolomics profiles & constraint-based modelling approaches Nathalie Poupin Workshop Modélisation du Métabolisme, Nov 2021, Bordeaux, France Conference papers hal-03807715v1
	Metabolic adaptations in insulin resistant and dyslipidemic minipigs ranging from lean to morbid obesity. Imene Bousahba , Jérémie David , Yves Guerin , Benoit Cohade , Didier Rémond 18. Conference on Trans-Pyrenean Investigations in Obesity and Diabetes, Nov 2021, Clermont-Ferrand, France Conference papers hal-03457729v1
	Modelling intrahepatic metabolic rewiring during the onset of obesity using arterio- venous blood metabolomics profiles Nathalie Poupin , Marie Tremblay-Franco , Cécile Canlet , Aurélien Amiel , Didier Rémond European RFMF Metabomeeting 2020, Jan 2020, Toulouse, France Conference papers hal-02948334v1
	Insights from metabolomic and molecular signatures to detect, in a blood sample, muscle anabolic resistance associated with catabolic situation. Case model of glucocorticoids effect in mini-pigs Sergio Polakof , Marie Tremblay-Franco , Nathalie Poupin , Florence Castelli , Jérémie David Fifth International Congress of Translational Research in Human Nutrition (ICTRHN), Jun 2019, Clermont-Ferrand, France Conference papers hal-02154641v1
	Analysis of OMICS data in the context of metabolic networks Nathalie Poupin Workshop "Analyse et interprétation des données en protéomique et métabolomique : points communs et spécificités", Mar 2018, Lyon, France Conference papers hal-02948297v1
	Modélisation du réseau métabolique des cellules de Leucémies Aiguës Myéloïdes pour comprendre les différences métaboliques liées à la mutation sur IDH1 Laurent Fernando , Lucille Stuani , Tony Lionel Palama , Tony Kaoma , Jean-Emmanuel Sarry Congrès de Spectrométrie de Masse, Métabolomique et Fluxomique (SMMAP), Oct 2017, Marne-la-Vallée, France Conference papers hal-02946080v1
	Exploring metabolic modulations using genome-scale network modelling and omics data Nathalie Poupin Workshop "Metabolism in Systems Biology", Nov 2016, Lille, France Conference papers hal-02948304v1
	Modélisation sous contraintes du métabolisme : une approche globale pour l’étude des modulations métaboliques Nathalie Poupin 1ères journées du club Métabo-Cancer GSO, Apr 2015, Toulouse, France Conference papers hal-02792590v1
	Les abondances isotopiques de l'azote comme marqueurs des adaptations métaboliques à la qualité de l'apport protéique : analyse et interprétation par modélisation chez le rat Nathalie Poupin , François Mariotti , Jean-François Huneau , Dominique D. Hermier , Hélène Fouillet 1er séminaire Abondances Isotopiques Naturelles en Nutrition et Santé, Jan 2014, Paris, France Conference papers hal-01598849v1
	Les signatures isotopiques des dérégulations du métabolisme protéino-énergétique lors du développement d'un syndrome métabolique chez le rat Nathalie Poupin , Jean-François Huneau , François Mariotti , Dominique D. Hermier , Tristan Mary-Huard 1er séminaire Abondances Isotopiques Naturelles en Nutrition et Santé, Jan 2014, Paris, France Conference papers hal-01598850v1
	d15N and d13C values in body pools are biomarkers of the protein-energy dysregulations of the metabolic syndrome onse Nathalie Poupin , J.F. Huneau , Tristan Mary-Huard , J.P. Godin , D. Hermier GEOMED 1st workshop on biomedical application of geochemistry, Aug 2013, Gargonza, Italy Conference papers hal-01562202v1
	Les abondances isotopiques naturelles témoignent de modulations nutritionnelles et physiopathologiques du métabolisme azoté : analyse par modélisation compartimentale Nathalie Poupin , François Mariotti , J.-F. Huneau , D. Hermier , Hélène Fouillet Journées francophones de Nutrition, Dec 2013, Bordeaux, France. pp.S29 - S30, ⟨10.1016/S0007-9960(13)70311-0⟩ Conference papers hal-01584713v1
	Les abondances isotopiques naturelles signent l’initiation nutritionnelle du syndrome métabolique. Nathalie Poupin , François Mariotti , Jean-François Huneau , Tristan Mary-Huard , Jean-Philippe Godin Journées Francophones de Nutrition, Dec 2012, Lyon, France Conference papers hal-01592265v1
	A new method for the multi-tissue estimation of protein turnover by compartmental analysis of the nitrogen isotope dynamics in rats fed a N-15-enriched diet Nathalie Poupin , Jean-François Huneau , François Mariotti , Cecile Bos , Daniel Tomé Experimental Biology Meeting 2011, Apr 2011, Washington D.C., France Conference papers hal-01186837v1

	Etude métabolomique par RMN de l'exposition chronique à faible dose de composés génotoxiques Cécile Canlet , Marie Tremblay-Franco , Roselyne Gautier , Yannick Brunato , Patricia Kembia-Kalombo 15èmes journées scientifiques du RFMF, May 2023, Perpignan, France Conference poster hal-04332320v1
	Métabolomique multiplateforme (MS, RMN) : étude de l’impact de l'ajout de TSP sur les données MS benedict Yanibada , Cécile Canlet , Carla Orlandi , Roselyne Gautier , Fabien Jourdan Congrès Analytics 2022, Sep 2022, Nantes, France Conference poster hal-04357965v1
	Characterization of human isogenic epithelial cell lines as a relevant tool to study colon carcinogenesis and interaction between genes and environment Arnaud Tête , Liana C. Arnaud , Hélène Le Mentec , Isabelle Gallais , Nathalie Poupin Society of Toxicology Annual Meeting (SOT 2022), Mar 2022, San Diego, United States. , 3579, pp.P204 Conference poster hal-03637792v1
	Study Protocol: A 2-Month Cross-Over Controlled Feeding Trial Investigating the Effect of Animal and Plant Protein Intake on the Metabolome and Cardiometabolic Health Gaïa Lépine , François Mariotti , Jean-François Huneau , Nathalie Poupin , Marie Tremblay-Franco Nutrition Live Online 2021, Jun 2021, Online, United States. 5 (Supplement_2), pp.1281, 2021, ⟨10.1093/cdn/nzab057_011⟩ Conference poster hal-03292189v1
	INPUT OF DEEP PHENOTYPING IN THE METABOLIC SYNDROME STRATIFICATION Stéphanie Monnerie , Mélanie Pétéra , Cécile Canlet , Florence Castelli , Benoit Colsch European RFMF Metabomeeting 2020, Jan 2020, Toulouse, France. , 262 p., 2020, Oral and Poster Abstracts European RMF Metabomeeting 2020 Conference poster hal-02505908v1
	MetExplore: Omics data analysis in the context of metabolic networks Maxime Chazalviel , Adrien Rohan , Nathalie Poupin , Florence Vinson , Clément Frainay European RFMF Metabomeeting 2020, Jan 2020, Toulouse, France. Conference poster hal-02948391v1
	Fast-Quenching Standard Comparison of two sampling and extraction protocols to perform metabolomic studies on human adherent cells Joran Villaret-Cazadamont , Noémie Butin , Jean-Francois Martin , Marie Tremblay-Franco , Cécile Canlet European RFMF Metabomeeting 2020, Jan 2020, Toulouse, France Conference poster hal-02948361v1
	Improving prediction of essential genes using context-specific metabolic network ensembles Pablo Rodríguez-Mier , Nathalie Poupin , Carlo de Blasio , Laurent Le Cam , Fabien Jourdan European RFMF Metabomeeting 2020, Jan 2020, Toulouse, France Conference poster hal-02948371v1
	Modelling hepatic metabolic changes during the onset of obesity using NMR metabolomics arterio-venous blood exploration in minipigs Nathalie Poupin , Marie Tremblay-Franco , Aurélien Amiel , Cécile Canlet , Didier Remond 12. Journées Scientifiques du Réseau Francophone de Métabolomique et Fluxomique RFMF, May 2019, Clermont-Ferrand, France. 168 p., 2019, Livre des résumés Conference poster hal-02162584v1
	Hepatic metabolomics and transcriptomics provide valuable insights on inflammatory and metabolic features in rats fed on a high fat diet but showing similar clinical phenotyping alterations Sergio Polakof , Marie Tremblay-Franco , Cécile Canlet , Jérémie David , Fabien Jourdan 12. Journées Scientifiques du Réseau Francophone de Métabolomique et Fluxomique RFMF, May 2019, Clermont-Ferrand, France. 168 p., 2019, Livre des résumés Conference poster hal-02162582v1
	Impaired postprandial skeletal muscle metabolism in a minipig model of insulin resistance: insights from arteriovenous and biopsy-based metabolomics analyses Marie Tremblay-Franco , Nathalie Poupin , Florence Castelli , Jérémie David , Marianne Jarzaguet 12. Journées Scientifiques du Réseau Francophone de Métabolomique et Fluxomique RFMF, May 2019, Clermont-Ferrand, France. 168 p., 2019, Livre des résumés Conference poster hal-02285596v1
	Un mélange équilibré de protéines végétales permet une homéostasie protéique tissulaire normale grâce à l’activation de remaniements métaboliques des acides aminés Hélène Fouillet , Didier Rémond , François Mariotti , Gaïa Lépine , Véronique Mathé Journées Francophones de Nutrition, Nov 2019, Rennes, France Conference poster hal-02948410v1
	Par rapport aux protéines de lait, un mélange de protéines de blé et de pois limite l’insulino-résistance et la lipogenèse de novo induites par un régime riche en lipides et saccharose Sergio Polakof , Jean-François Huneau , Dominique Hermier , Didier Remond , Gaîa Lépine Journées Francophones de Nutrition, Nov 2019, Rennes, France. 2019, JFN 2019 Livre des résumés Conference poster hal-02383599v1
	Compared to animal proteins, plant proteins induce metabolic reorientations that ensure protein homeostasis and are associated with a reduced high-fat-induced insulin resistance Sergio Polakof , Gaïa Lépine , Véronique Mathé , Jérémie David , Didier Remond NuGOweek 2019, Sep 2019, Berne, Switzerland Conference poster hal-04443316v1
	Study of the hepatic metabolic effects induced by PFOA exposure using a multiplatform metabolomics approach Joran Villaret-Cazadamont , Noemie Butin , Cécile Canlet , Marie Tremblay-Franco , Roselyne Gautier 55. Congress of the European-Societies-of-Toxicology (EUROTOX) - Toxicology - Science Providing Solutions, Sep 2019, Helsinki, Finland. ELSEVIER IRELAND LTD, 2019, TOXICOLOGY LETTERS Conference poster hal-02306108v1
	Exploration of the hepatic metabolic effects induced by PFOA exposure using global & combined metabolomics approaches Joran Villaret-Cazadamont , Noémie Butin , Floriant Bellvert , Cécile Canlet , Elodie Person Gordon Research Conference on Environmental Endocrine Disruptors, Jun 2018, Les Diablerets, Vaud, Switzerland Conference poster hal-04678711v1
	Modeling hepatic metabolic changes during the onset of obesity from metabolomics arterio-venous blood exploration in minipigs Nathalie Poupin , Marie Tremblay-Franco , Aurélien Amiel , Cécile Canlet , Didier Remond Copenhagen Bioscience Conference 2017: Where big-data gets translated into knowledge, May 2017, Copenhague, Netherlands. 2017, Bioscience Conference 2017 Conference poster hal-01606420v1
	Natural abundance of nitrogen isotopes in amino acids are biomarkers of the metabolic syndrome onset Jean-François Huneau , Klaus-Jürgen Petzke , Nathalie Poupin , Tristan Mary-Huard , Olivier Mantha 12th european nutrition conference, Oct 2015, Berlin, Germany. KARGER, 67, pp.1, 2015, Annals of Nutrition and Metabolism Conference poster hal-01572322v1

	Analysing human metabolic networks using metabolomics Nathalie Poupin , Fabien Jourdan Metabolomics as a Tool in Nutrition Research, Elsevier, pp.85-114, 2015, ⟨10.1016/B978-1-78242-084-2.00005-8⟩ Book sections hal-03318813v1
	Human metabolic networks and metabolomics Fabien Jourdan , Nathalie Poupin Metabolomics as tool in nutrition research, Woodhead publishing Limited, 2014 Book sections hal-01187878v1

	A strategy to detect metabolic changes induced by exposure to chemicals from large sets of condition-specific metabolic models computed with enumeration techniques Louison Fresnais , Olivier Perin , Anne Riu , Romain Grall , Alban Ott 2024 Preprints, Working Papers, ... hal-04188513v2
	Pathway analysis in metabolomics: pitfalls and best practice for the use of over-representation analysis Cecilia Wieder , Clément Frainay , Nathalie Poupin , Pablo Rodríguez-Mier , Florence Vinson 2021 Preprints, Working Papers, ... hal-03240376v1
	Combinatory therapy targeting mitochondrial oxidative phosphorylation improves efficacy of IDH mutant inhibitors in acute myeloid leukemia Lucille Stuani , Marie Sabatier , Feng Wang , Nathalie Poupin , Claudie Bosc 2020 Preprints, Working Papers, ... hal-02935177v1
	DEXOM: Diversity-based enumeration of optimal context-specific metabolic networks Pablo Rodríguez-Mier , Nathalie Poupin , Carlo de Blasio , Laurent Le Cam , Fabien Jourdan 2020 Preprints, Working Papers, ... hal-02935163v1

	Les abondances naturelles des isotopes stables de l'azote chez le rat : facteurs de variabilité et application pour l'étude des flux azotés et de l'impact métabolique de conditions nutritionnelles et physiopathologiques par modélisation compartimentale. Nathalie Poupin Sciences agricoles. AgroParisTech, 2013. Français. ⟨NNT : 2013AGPT0003⟩ Theses pastel-00927219v1

Nathalie Poupin

Publications

Genome scale metabolic network modelling for metabolic profile predictions

PathIntegrate: Multivariate modelling approaches for pathway-based multi-omics data integration

Weight of evidence evaluation of the metabolism disrupting effects of triphenyl phosphate using an expert knowledge elicitation approach

A strategy to detect metabolic changes induced by exposure to chemicals from large sets of condition-specific metabolic models computed with enumeration techniques

Challenges and perspectives for naming lipids in the context of lipidomics

Lipidomic Profiling of PFOA-Exposed Mouse Liver by Multi-Modal Mass Spectrometry Analysis

Compared with Milk Protein, a Wheat and Pea Protein Blend Reduces High-Fat, High-Sucrose Induced Metabolic Dysregulations while Similarly Supporting Tissue Protein Anabolism in Rats

Despite similar clinical features metabolomics reveals distinct signatures in insulin resistant and progressively obese minipigs

Avoiding the Misuse of Pathway Analysis Tools in Environmental Metabolomics

SOC-II-03 Zebrafish as a model for chemical induced adipogenesis and related metabolic diseases

How Does Your Body Deal With Fast-Food Meals?

Transgenerational metabolomic fingerprints in mice ancestrally exposed to the obesogen TBT

Mitochondrial metabolism supports resistance to IDH mutant inhibitors in acute myeloid leukemia

DEXOM: Diversity-based enumeration of optimal context-specific metabolic networks

Pathway analysis in metabolomics: Recommendations for the use of over-representation analysis

Multiplatform metabolomics for an integrative exploration of metabolic syndrome in older men

Improving lipid mapping in Genome Scale Metabolic Networks using ontologies

Postprandial NMR-Based Metabolic Exchanges Reflect Impaired Phenotypic Flexibility across Splanchnic Organs in the Obese Yucatan Mini-Pig

An Optimized Dual Extraction Method for the Simultaneous and Accurate Analysis of Polar Metabolites and Lipids Carried out on Single Biological Samples

Addendum: An Optimised Dual Extraction Method for the Simultaneous and Accurate Analysis of Polar Metabolites and Lipids Carried out on Single Biological Samples. Metabolites 2020, 10, 338

An Integrated Analysis of miRNA and Gene Expression Changes in Response to an Obesogenic Diet to Explore the Impact of Transgenerational Supplementation with Omega 3 Fatty Acids

Large-Scale Modeling Approach Reveals Functional Metabolic Shifts during Hepatic Differentiation

Arterio-venous metabolomics exploration reveals major changes across liver and intestine in the obese Yucatan minipig

An untargeted metabolomics approach to explore the metabolic modulation of HepG2 cells exposed to low doses of bisphenol A and 17β-estradiol 2

Early changes in tissue amino acid metabolism and nutrient routing in rats fed a high-fat diet: evidence from natural isotope abundances of nitrogen and carbon in tissue proteins

Integrated transcriptomics and metabolomics reveal signatures of lipid metabolism dysregulation in HepaRG liver cells exposed to PCB 126

MetExploreViz: web component for interactive metabolic network visualization

MetExplore: collaborative edition and exploration of metabolic networks

A computational solution to automatically map metabolite libraries in the context of genome scale metabolic networks

Effects of dark chocolate and cocoa consumption on endothelial function and arterial stiffness in overweight adults

Natural Isotopic Signatures of Variations in Body Nitrogen Fluxes: A Compartmental Model Analysis

Isotopic and modeling investigation of long-term protein turnover in rat tissues

Protein intake, calcium balance and health consequences

Impact of the diet on net endogenous acid production and acid–base balance

The nature of the dietary protein impacts the tissue-to-diet N-15 discrimination factors in laboratory rats

Exploration multi-omique et in silico des effets transgénérationels et sexe-spécifiques induits par le TBT, un composé obésogène, sur le métabolisme hépatique de la souris

Exploring the impact of plant protein vs. animal protein-rich diets in men at cardiometabolic risk: insights from plasma metabolome signatures

Arteriovenous metabolomic approach reveals specific metabolite exchanges across organs and provides unique insights for understanding underlying metabolic perturbations in obese and insulin-resistant minipigs

L’exploration des échanges inter-organes par métabolomique artérioveineuse offre une perspective unique pour comprendre les perturbations métaboliques sous-jacentes dans l’installation de l'obésité et de l'insulino-résistance chez les miniporcs

SAMBA, a recommendation system for biomarker discovery using metabolic networks

Modelling the muscle metabolic response in anabolic and catabolic states using arterio-venous blood metabolomics profiles

Making Sense of lipidomics analyses using metabolic networks

Multi-omics phenotyping highlights organ-specific metabolic and inflammatory shifts associated with differential plant and animal protein intake in high fat fed rats

Modelling intrahepatic metabolic rewiring during the onset of obesity using arterio-venous blood metabolomics profiles & constraint-based modelling approaches

Metabolic adaptations in insulin resistant and dyslipidemic minipigs ranging from lean to morbid obesity.

Modelling intrahepatic metabolic rewiring during the onset of obesity using arterio- venous blood metabolomics profiles

Insights from metabolomic and molecular signatures to detect, in a blood sample, muscle anabolic resistance associated with catabolic situation. Case model of glucocorticoids effect in mini-pigs

Analysis of OMICS data in the context of metabolic networks

Modélisation du réseau métabolique des cellules de Leucémies Aiguës Myéloïdes pour comprendre les différences métaboliques liées à la mutation sur IDH1

Exploring metabolic modulations using genome-scale network modelling and omics data

Modélisation sous contraintes du métabolisme : une approche globale pour l’étude des modulations métaboliques

Les abondances isotopiques de l'azote comme marqueurs des adaptations métaboliques à la qualité de l'apport protéique : analyse et interprétation par modélisation chez le rat

Les signatures isotopiques des dérégulations du métabolisme protéino-énergétique lors du développement d'un syndrome métabolique chez le rat

d15N and d13C values in body pools are biomarkers of the protein-energy dysregulations of the metabolic syndrome onse

Les abondances isotopiques naturelles témoignent de modulations nutritionnelles et physiopathologiques du métabolisme azoté : analyse par modélisation compartimentale

Les abondances isotopiques naturelles signent l’initiation nutritionnelle du syndrome métabolique.

A new method for the multi-tissue estimation of protein turnover by compartmental analysis of the nitrogen isotope dynamics in rats fed a N-15-enriched diet

Etude métabolomique par RMN de l'exposition chronique à faible dose de composés génotoxiques

Métabolomique multiplateforme (MS, RMN) : étude de l’impact de l'ajout de TSP sur les données MS

Characterization of human isogenic epithelial cell lines as a relevant tool to study colon carcinogenesis and interaction between genes and environment

Study Protocol: A 2-Month Cross-Over Controlled Feeding Trial Investigating the Effect of Animal and Plant Protein Intake on the Metabolome and Cardiometabolic Health

INPUT OF DEEP PHENOTYPING IN THE METABOLIC SYNDROME STRATIFICATION

MetExplore: Omics data analysis in the context of metabolic networks

Fast-Quenching Standard Comparison of two sampling and extraction protocols to perform metabolomic studies on human adherent cells

Improving prediction of essential genes using context-specific metabolic network ensembles

Modelling hepatic metabolic changes during the onset of obesity using NMR metabolomics arterio-venous blood exploration in minipigs

Hepatic metabolomics and transcriptomics provide valuable insights on inflammatory and metabolic features in rats fed on a high fat diet but showing similar clinical phenotyping alterations

Impaired postprandial skeletal muscle metabolism in a minipig model of insulin resistance: insights from arteriovenous and biopsy-based metabolomics analyses

Un mélange équilibré de protéines végétales permet une homéostasie protéique tissulaire normale grâce à l’activation de remaniements métaboliques des acides aminés

Par rapport aux protéines de lait, un mélange de protéines de blé et de pois limite l’insulino-résistance et la lipogenèse de novo induites par un régime riche en lipides et saccharose

Compared to animal proteins, plant proteins induce metabolic reorientations that ensure protein homeostasis and are associated with a reduced high-fat-induced insulin resistance

Study of the hepatic metabolic effects induced by PFOA exposure using a multiplatform metabolomics approach

Exploration of the hepatic metabolic effects induced by PFOA exposure using global & combined metabolomics approaches

Modeling hepatic metabolic changes during the onset of obesity from metabolomics arterio-venous blood exploration in minipigs

Natural abundance of nitrogen isotopes in amino acids are biomarkers of the metabolic syndrome onset

Analysing human metabolic networks using metabolomics

Human metabolic networks and metabolomics

A strategy to detect metabolic changes induced by exposure to chemicals from large sets of condition-specific metabolic models computed with enumeration techniques