Nicolas Delsuc

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Publications

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Arginine-Tryptophan Peptides Enhancing Antibacterial and Anticancer Effects of Ruthenium(II) Polypyridyl Complex Photosensitizers

Xiao Ying Ng , Kar Wai Fong , Lik Voon Kiew , Pooi Yin Chung , Yun Khoon Liew et al.
ACS Omega, 2025, 10 (29), pp.31452-31465. ⟨10.1021/acsomega.5c00997⟩
Article dans une revue hal-05213183 v1
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Angle-dependent spin crossover properties in polymorphic iron(ii) complexes based on pyridine-triazole derivatives

Emmelyne Cuza , Nicolas Delsuc , Jerôme Marrot , William Shepard , Clotilde Policar et al.
Dalton Transactions, 2025, ⟨10.1039/d4dt03376k⟩
Article dans une revue hal-05029258 v1
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Inorganic chemical biology and metal complexes in cells: from the design of cellular models to evaluate antioxidant activity to the characterization of metal complexes in cells

Clotilde Policar , Christine Rampon , Alice Balfourier , Michel Volovitch , Sophie Vriz et al.
Comptes Rendus. Chimie, 2025, 28 (G1), pp.397-421. ⟨10.5802/crchim.339⟩
Article dans une revue hal-05354269 v1
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SOD mimics delivered to the gut using lactic acid bacteria mitigate the colitis symptoms in a mouse model of Inflammatory Bowel Diseases

Gabrielle Schanne , Amandine Vincent , Florian Chain , Pauline Ruffié , Célia Carbonne et al.
Free Radical Research, In press, ⟨10.1080/10715762.2025.2478121⟩
Article dans une revue hal-04999251 v1
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Novel ruthenium(II) polypyridyl complexes conjugated with bis-dipicolylamine as antibacterial photosensitisers

Kar Wai Fong , Xiao Ying Ng , Lik Voon Kiew , Yun Khoon Liew , Pooi Yin Chung et al.
Photochemical & Photobiological Sciences , 2025, Online ahead of print. ⟨10.1007/s43630-025-00790-z⟩
Article dans une revue hal-05360617 v1
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Decoding the mechanism for cytotoxicity in thiolato-bridged triosmium carbonyl clusters: from serum reactivity to cellular impact

Xin Liang , Hélène C Bertrand , Nicolas Delsuc , Bohong Huang , Weng Kee Leong et al.
European Journal of Biochemistry, 2025, ⟨10.1007/s00775-025-02127-8⟩
Article dans une revue hal-05361708 v1
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Piezoelectric and microfluidic tuning of an infrared cavity for vibrational polariton studies

Wei Wang , Jaime de la Fuente Diez , Nicolas Delsuc , Juan Peng , Riccardo Spezia et al.
Lab on a Chip, 2024, 24 (9), pp.2497-2505. ⟨10.1039/D3LC01101A⟩
Article dans une revue hal-04572532 v1
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Metal complexes in cells: from design of catalytic antioxidants to imaging metal ions and designing metal-based probes in X-ray fluorescence and IR-imaging, a multidisciplinary collaborative journey in bioinorganic chemistry and inorganic chemical biology

Clotilde Policar , Nicolas Delsuc , Hélène Charlotte Bertrand
Comptes Rendus. Chimie, 2024, 27, pp.117-141. ⟨10.5802/crchim.295⟩
Article dans une revue hal-05354322 v1
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Cellular evaluation of superoxide dismutase mimics as catalytic drugs: Challenges and opportunities

Gabrielle Schanne , Sylvie Demignot , Clotilde Policar , Nicolas Delsuc
Coordination Chemistry Reviews, 2024, 514, pp.215906. ⟨10.1016/j.ccr.2024.215906⟩
Article dans une revue (article de synthèse) hal-04573377 v1
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Ruthenium(II) polypyridyl complexes as emerging photosensitisers for antibacterial photodynamic therapy

Ng Xiao Ying , Fong Kar Wai , Kiew Lik Voon , Katrina Chung Pooi Yin , Liew Yun Khoon et al.
Journal of Inorganic Biochemistry, 2023, pp.112425. ⟨10.1016/j.jinorgbio.2023.112425⟩
Article dans une revue hal-04274612 v1
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Improvement of Peptidyl Copper Complexes Mimicking Catalase: A Subtle Balance between Thermodynamic Stability and Resistance towards H2O2 Degradation

Yaqine Ben Hadj Hammouda , Koudedja Coulibaly , Alimatou Bathily , Magdalene Teoh Sook Han , Clotilde Policar et al.
Molecules, 2022, 27 (17), pp.5476. ⟨10.3390/molecules27175476⟩
Article dans une revue hal-03776249 v1
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Inertness of Superoxide Dismutase Mimics Mn(II) Complexes Based on an Open-Chain Ligand, Bioactivity, and Detection in Intestinal Epithelial Cells

Gabrielle Schanne , Martha Zoumpoulaki , Géraldine Gazzah , Amandine Vincent , Hugues Preud'Homme et al.
Oxidative Medicine and Cellular Longevity, 2022, 2022, pp.3858122. ⟨10.1155/2022/3858122⟩
Article dans une revue hal-03651845 v1
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Deciphering the Metal Speciation in Low‐Molecular‐Weight Complexes by IMS‐MS: Application to the Detection of Manganese Superoxide Dismutase Mimics in Cell Lysates

Martha Zoumpoulaki , Gabrielle Schanne , Nicolas Delsuc , Hugues Preud'Homme , Elodie Quévrain et al.
Angewandte Chemie International Edition, 2022, ⟨10.1002/anie.202203066⟩
Article dans une revue hal-03699781 v1
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SOD mimics: From the tool box of the chemists to cellular studies

Clotilde Policar , Jean Bouvet , Hélène C Bertrand , Nicolas Delsuc
Current Opinion in Chemical Biology, 2022, 67, pp.102109. ⟨10.1016/j.cbpa.2021.102109⟩
Article dans une revue hal-03834587 v1
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Cellular Detection of a Mitochondria Targeted Brominated Vinyl Triphenylamine Optical Probe (TP−Br) by X‐Ray Fluorescence Microscopy

Sounderya Nagarajan , Florent Poyer , Laura Fourmois , Delphine Naud-Martin , Kadda Medjoubi et al.
Chemistry - A European Journal, 2022, 28 (15), pp.e202104424. ⟨10.1002/chem.202104424⟩
Article dans une revue hal-03768555 v1
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Rhenium carbonyl complexes bearing methylated triphenylphosphonium cations as antibody-free mitochondria trackers for X-ray fluorescence imaging

Gabrielle Schanne , Lucas Henry , How Chee Ong , Andrea Somogyi , Kadda Medjoubi et al.
Inorganic Chemistry Frontiers, 2021, 8 (16), pp.3905-3915. ⟨10.1039/d1qi00542a⟩
Article dans une revue hal-03834592 v1
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A di-Copper Peptidyl Complex Mimics the Activity of Catalase, a Key Antioxidant Metalloenzyme

Koudedja Coulibaly , Marion Thauvin , Adyn Melenbacher , Clara Testard , Evangelia Trigoni et al.
Inorganic Chemistry, 2021, Online ahead of print. ⟨10.1021/acs.inorgchem.0c03718⟩
Article dans une revue hal-03262072 v1
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Evaluation of the compounds commonly known as superoxide dismutase and catalase mimics in cellular models

Amandine Vincent , Marion Thauvin , Elodie Quévrain , Emilie Mathieu , Sarah Layani-Moreno Layani et al.
Journal of Inorganic Biochemistry, 2021, 219, pp.111431. ⟨10.1016/j.jinorgbio.2021.111431⟩
Article dans une revue hal-03187067 v1
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Intracellular location matters: rationalization of the anti-inflammatory activity of a manganese( ii ) superoxide dismutase mimic complex

Emilie Mathieu , Anne-Sophie Bernard , Elodie Quévrain , Martha Zoumpoulaki , Sébastien Iriart et al.
Chemical Communications, 2020, 56 (57), pp.7885-7888. ⟨10.1039/d0cc03398g⟩
Article dans une revue hal-03180781 v1
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Anti-inflammatory activity of superoxide dismutase mimics functionalized with cell- penetrating peptides

Emilie Mathieu , Anne-Sophie Bernard , H. Y. Vincent Ching , Andrea Somogyi , Kadda Medjoubi et al.
Dalton Transactions, 2020, 49 (7), pp.2323-2330. ⟨10.1039/C9DT04619D⟩
Article dans une revue hal-02521252 v1
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Differentiation of neural-type cells on multi-scale ordered collagen-silica bionanocomposites

Nicolas Debons , Dounia Dems , Christophe Hélary , Sylvain Le Grill , Lise Picaut et al.
Biomaterials Science, 2020, ⟨10.1039/C9BM01029G⟩
Article dans une revue hal-02456407 v1
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An easy-to-implement combinatorial approach involving an activity-based assay for the discovery of a peptidyl copper complex mimicking superoxide dismutase

Amandine Vincent , Jennifer Rodon Fores , Elodie Tauziet , Elodie Quévrain , Ágnes Dancs et al.
Chemical Communications, 2020, 56 (3), pp.399-402. ⟨10.1039/C9CC07920C⟩
Article dans une revue hal-02378888 v1

Anti-inflammatory activity of superoxide dismutase mimics functionalized with cell-penetrating peptides

Emilie Mathieu , Anne-Sophie Bernard , H. Ching , Andrea Somogyi , Kadda Medjoubi et al.
Dalton Transactions, 2020, 49 (7), pp.2323-2330. ⟨10.1039/c9dt04619d⟩
Article dans une revue hal-04977335 v1
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Recent Emergence of Rhenium(I) Tricarbonyl Complexes as Photosensitisers for Cancer Therapy

Hui Shan Liew , Chun-Wai Mai , Mohd Zulkefeli , Thiagarajan Madheswaran , Lik Voon Kiew et al.
Molecules, 2020, 25 (18), pp.4176. ⟨10.3390/molecules25184176⟩
Article dans une revue hal-02988212 v1
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Labeling of Hyaluronic Acids with a Rhenium-Tricarbonyl Tag and Percutaneous Penetration Studied by Multimodal Imaging

Lucas Henry , Nicolas Delsuc , Cécile Laugel , François Lambert , Christophe Sandt et al.
Bioconjugate Chemistry, 2018, 29 (4), pp.987-991. ⟨10.1021/acs.bioconjchem.7b00825⟩
Article dans une revue hal-02009811 v1
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A metallo pro-drug to target Cu(II) in the context of Alzheimer's disease

Amandine Conte-Daban , Vinita Ambike , Régis Guillot , Nicolas Delsuc , Clotilde Policar et al.
Chemistry - A European Journal, 2018, 24 (20), pp.5095-5099. ⟨10.1002/chem.201706049⟩
Article dans une revue hal-01685637 v1
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Graftable SCoMPIs enable the labeling and X-ray fluorescence imaging of proteins

Sarah Hostachy , Marie Masuda , Takayuki Miki , Itaru Hamachi , Sandrine Sagan et al.
Chemical Science, 2018, 9 (19), pp.4483-4487. ⟨10.1039/C8SC00886H⟩
Article dans une revue hal-01905965 v1
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Host-Guest System Based on Collagen-Like Triple-Helix Hybridization

Nicolas Delsuc , Shohei Uchinomiya , Akio Ojida , Itaru Hamachi
Chemical Communications, 2017, 53, pp.6856-6859 ⟨10.1039/C7CC03055J⟩
Article dans une revue hal-01535603 v1
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Re(I) carbonyl complexes: Multimodal platforms for inorganic chemical biology

Sarah Hostachy , Clotilde Policar , Nicolas Delsuc
Coordination Chemistry Reviews, 2017, 351, pp.172-188. ⟨10.1016/j.ccr.2017.05.004⟩
Article dans une revue hal-01533375 v1
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An All-in-One Molecule for the One-Step Synthesis of Functional Hybrid Silica Particles with Tunable Sizes

Julien Graffion , Dounia Dems , Mesut Demirelli , Thibaud Coradin , Nicolas Delsuc et al.
European Journal of Inorganic Chemistry, 2017, 2017 (43), pp.5047-5051. ⟨10.1002/ejic.201701181⟩
Article dans une revue hal-02121324 v1
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A Cell-Penetrant Manganese SOD-Mimic Is Able To Complement MnSOD and Exerts an Antiinflammatory Effect on Cellular and Animal Models of Inflammatory Bowel Diseases

Emilie Mathieu , Anne-Sophie Bernard , Nicolas Delsuc , Elodie Quévrain , Géraldine Gazzah et al.
Inorganic Chemistry, 2017, 56 (5), pp.2545-2555. ⟨10.1021/acs.inorgchem.6b02695⟩
Article dans une revue hal-01473825 v1
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New insight into the structural, electrochemical and biological aspects of macroacyclic Cu(II) complexes derived from S-substituted dithiocarbazate schiff bases

May Lee Low , Laure Maigre , Mohamed Ibrahim M. Tahir , Edward R. T. Tiekink , Pierre Dorlet et al.
European Journal of Medicinal Chemistry, 2016, 120, pp.1-12. ⟨10.1016/j.ejmech.2016.04.027⟩
Article dans une revue hal-01362850 v1
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Bioinspired superoxide-dismutase mimics: The effects of functionalization with cationic polyarginine peptides

H.Y. Vincent Ching , Isabell Kenkel , Nicolas Delsuc , Emilie Mathieu , Ivana Ivanović-Burmazović et al.
Journal of Inorganic Biochemistry, 2016, 160, pp.172-179. ⟨10.1016/j.jinorgbio.2016.01.025⟩
Article dans une revue hal-01288188 v1
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Photophysical properties of single core multimodal probe for imaging (SCoMPI) in a membrane model and in cells.

S. Hostachy , J.-M. Swiecicki , C. Sandt , Nicolas Delsuc , Clotilde Policar
Dalton Transactions, 2016, 45 (4), pp.2791-2795. ⟨10.1093/ecco-jcc/jjw005⟩
Article dans une revue hal-01254689 v1

An easy-to-detect nona-arginine peptide for epidermal targeting.

Sylvain Clède , Nicolas Delsuc , Cécile Laugel , François Lambert , Christophe Sandt et al.
Chemical Communications, 2015, 51, pp.2687-2689. ⟨10.1039/C4CC08737B⟩
Article dans une revue hal-01103088 v1

Synthesis, characterization and biological activity of Cu(II), Zn(II) and Re(I) complexes derived from S-benzyldithiocarbazate and 3-acetylcoumarin.

May Lee Low , Georgiana Paulus , Pierre Dorlet , Régis Guillot , Rozita Rosli et al.
BioMetals, 2015, 28 (3), pp.553-566. ⟨10.1007/s10534-015-9831-2⟩
Article dans une revue hal-01120951 v1

Conjugation of a New Series of Dithiocarbazate Schiff Base Copper(II) Complexes with Vectors Selected to Enhance Antibacterial Activity.

May Lee Low , Laure Maigre , Pierre Dorlet , Régis Guillot , Jean-Marie Pagès et al.
Bioconjugate Chemistry, 2014, 25 (12), pp.2269-2284. ⟨10.1021/bc5004907⟩
Article dans une revue hal-01081881 v1

3-substituted prolines: from synthesis to structural applications, from peptides to foldamers.

Céline Mothes , Cécile Caumes , Alexandre Guez , Héloïse Boullet , Thomas Gendrineau et al.
Molecules, 2013, 18 ((2)), pp.2307-27. ⟨10.3390/molecules18022307⟩
Article dans une revue hal-00797316 v1

Homooligomers of substituted prolines and beta-prolines: syntheses and secondary structure investigation

Cécile Caumes , Nicolas Delsuc , Redouane Beni Azza , Isabelle Correia , Fabrice Chemla et al.
New Journal of Chemistry, 2013, 37 (5), pp.1312-1319. ⟨10.1039/c3nj00127j⟩
Article dans une revue hal-01362673 v1
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Assessing the folding propensity of aliphatic units within helical aromatic oligoamide foldamers

Nicolas Delsuc , Legiso Poniman , Jean-Michel Léger , Ivan Huc
Tetrahedron, 2012, 68 (23), pp.4464-4469. ⟨10.1016/j.tet.2011.11.097⟩
Article dans une revue istex hal-00695546 v1

Synchrotron radiation FTIR detection of a metal-carbonyl tamoxifen analog. Correlation with luminescence microscopy to study its subcellular distribution.

Sylvain Clède , François Lambert , Christophe Sandt , Zoher Gueroui , Nicolas Delsuc et al.
Biotechnology Advances, 2012, 51 (3), pp.393-395. ⟨10.1016/j.biotechadv.2012.01.023⟩
Article dans une revue istex hal-00680917 v1

Relative helix-helix conformations in branched aromatic oligoamide foldamers.

Nicolas Delsuc , Stéphane Massip , Jean-Michel Léger , Brice Kauffmann , Ivan Huc
Journal of the American Chemical Society, 2011, 133 ((9)), pp.3165-72. ⟨10.1021/ja110677a⟩
Article dans une revue hal-00723788 v1

Development of tools for tine tuning of peptide secondary structures, Syntheses, Structural and pharmacological applications

Roba Moumné , Nicolas Delsuc , Olivier Lequin , Karine Guitot , Céline Mothes et al.
Biopolymers, 2011, 96 ((4)), pp.459-459
Article dans une revue hal-00649139 v1

Cascading transformations within a dynamic self-assembled system.

Victoria E Campbell , Xavier de Hatten , Nicolas Delsuc , Brice Kauffmann , Ivan Huc et al.
Nature Chemistry, 2010, 2 (8), pp.684-7. ⟨10.1038/nchem.693⟩
Article dans une revue istex hal-00593183 v1

Helical aromatic oligoamide foldamers as organizational scaffolds for photoinduced charge transfer.

Martin Wolffs , Nicolas Delsuc , Dirk Veldman , Vân Anh Nguyên , René M Williams et al.
Journal of the American Chemical Society, 2009, 131 ((13)), pp.4819-29. ⟨10.1021/ja809367u⟩
Article dans une revue hal-00677462 v1

Interplay of interactions governing the dynamic conversions of acyclic and macrocyclic helicates.

Victoria E Campbell , Xavier de Hatten , Nicolas Delsuc , Brice Kauffmann , Ivan Huc et al.
Chemistry - A European Journal, 2009, 15 ((25)), pp.6138-42. ⟨10.1002/chem.200900693⟩
Article dans une revue hal-00733991 v1

Metal-directed dynamic formation of tertiary structure in foldamer assemblies: orienting helices at an angle.

Nicolas Delsuc , Marie Hutin , Victoria E Campbell , Brice Kauffmann , Jonathan R Nitschke et al.
Chemistry - A European Journal, 2008, 14 ((24)), pp.7140-3. ⟨10.1002/chem.200800988⟩
Article dans une revue istex hal-00733996 v1

Kinetics of helix-handedness inversion: folding and unfolding in aromatic amide oligomers.

Nicolas Delsuc , Takahiro Kawanami , Julien Lefeuvre , Atsuomi Shundo , Hirotaka Ihara et al.
ChemPhysChem, 2008, 9 ((13)), pp.1882-90. ⟨10.1002/cphc.200800310⟩
Article dans une revue istex hal-00733995 v1

Proteomorphous objects from abiotic backbones.

Nicolas Delsuc , J.M Leger , Stéphane Massip , Ivan Huc
Angewandte Chemie International Edition, 2007, 46, pp.214-217
Article dans une revue hal-00170390 v1

The herringbone helix: a noncanonical folding in aromatic-aliphatic peptides.

Nicolas Delsuc , Frédéric Godde , Brice Kauffmann , Jean-Michel Léger , Ivan Huc
Journal of the American Chemical Society, 2007, 129 ((37)), pp.11348-9. ⟨10.1021/ja074285s⟩
Article dans une revue istex hal-00689883 v1

Proteomorphous objects from abiotic backbones.

Nicolas Delsuc , Jean-Michel Léger , Stéphane Massip , Ivan Huc
Angewandte Chemie International Edition, 2007, 46 ((1)-(2)), pp.214-7. ⟨10.1002/anie.200603390⟩
Article dans une revue istex hal-00733997 v1

Vibrational circular dichroism and ab initio structure elucidation of an aromatic foldamer.

Thierry Buffeteau , Laurent Ducasse , Legiso Poniman , Nicolas Delsuc , Ivan Huc
Chemical Communications, 2006, (25), pp.2714-6. ⟨10.1039/b604462j⟩
Article dans une revue istex hal-00733998 v1

Probing helix propensity of monomers within a helical oligomer.

Christel Dolain , Jean-Michel Léger , Nicolas Delsuc , Heinz Gornitzka , Ivan Huc
Proceedings of the National Academy of Sciences of the United States of America, 2005, 102 ((45)), pp.16146-51. ⟨10.1073/pnas.0506262102⟩
Article dans une revue hal-00734000 v1

Probing helix propensity of monomers with in a helical oligomer

Heinz Gornitzka , Christel Dolain , Jean-Michel Leger , Nicolas Delsuc , Ivan Huc
Proceedings of the National Academy of Sciences of the United States of America, 2005, 102, pp.16146-16151
Article dans une revue hal-00361606 v1
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Engineering Peptidyl and Protein Glutathione Peroxidase Mimics

Nicolas Delsuc
Peptide and Protein Engineering for Biotechnological and Therapeutic Applications, WORLD SCIENTIFIC, pp.247-278, 2023, 978-981-12-6165-7. ⟨10.1142/9789811261664_0006⟩
Chapitre d'ouvrage hal-04274615 v1

Mimes synthétiques de structures tertiaires des proteines

Nicolas Delsuc , Ivan Huc , Brice Kauffmann , Jean-Michel Léger , Stéphane Massip
Mimes synthétiques de structures tertiaires des protéines, May 2007, Dinard, France
Communication dans un congrès hal-00786494 v1