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Nicolas Inguimbert

Since 2009 Full Professor at UPVD
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Publications

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Predatory and Defensive Strategies in Cone Snails

Zahrmina Ratibou , Nicolas Inguimbert , Sébastien Dutertre
Toxins, 2024, 16 (2), pp.94. ⟨10.3390/toxins16020094⟩
Article dans une revue hal-04549178v1

Bergofungin D, a peptaibol template for the introduction of chemical modifications, synthesis of analogs and comparative studies of their structures

Sanjit Das , Khoubaib Ben Haj Salah , Emmanuel Wenger , Baptiste Legrand , Claude Didierjean
Journal of Peptide Science, 2024, ⟨10.1002/psc.3598⟩
Article dans une revue hal-04549901v1

A new mitochondrial probe combining pyrene and a triphenylphosphonium salt for cellular oxygen and free radical detection via fluorescence lifetime measurements

Mohamad Jamal Wawi , Christoph Mahler , Nicolas Inguimbert , Todd Marder , Anne-Cécile Ribou
Free Radical Research, 2022, 56 (3-4), pp.258-272. ⟨10.1080/10715762.2022.2077202⟩
Article dans une revue hal-03969956v1

Mapping the N-Terminal Hexokinase-I Binding Site onto Voltage-Dependent Anion Channel-1 To Block Peripheral Nerve Demyelination

Benoit Gautier , Mélanie Forêt Jacquard , Sophie Guelfi , Scarlette Abbou , Elisa Gonzalez
Journal of Medicinal Chemistry, 2022, 65 (17), pp.11633-11647. ⟨10.1021/acs.jmedchem.2c00411⟩
Article dans une revue hal-03987562v1

Synthesis and Characterization of Bis‐1,2,3‐Triazole Ligand and its Corresponding Copper Complex for the Development of Electrochemical Affinity Biosensors

Hussein Kanso , Amani Ben Jrad , Nicolas Inguimbert , Wassim Rammal , Christian Philouze
Chemistry - A European Journal, 2021, ⟨10.1002/chem.202100250⟩
Article dans une revue hal-03270221v1
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D-Peptidase Activity in a Marine Mollusk Detoxifies a Nonribosomal Cyclic Lipopeptide: An Ecological Model to Study Antibiotic Resistance

Laurine Darcel , Louis Bornancin , Delphine Raviglione , Isabelle Bonnard , Suzanne Mills
Journal of Medicinal Chemistry, inPress, ⟨10.1021/acs.jmedchem.1c00249⟩
Article dans une revue hal-03212973v1

Peptide Vectors Carry Pyrene to Cell Organelles Allowing Real‐Time Quantification of Free Radicals in Mitochondria by Time‐Resolved Fluorescence Microscopy

Mohamad Jamal Wawi , Amandine Bijoux , Nicolas Inguimbert , Christoph Mahler , Stephan Wagner
ChemBioChem, 2021, 22, pp.1-11. ⟨10.1002/cbic.202000845⟩
Article dans une revue hal-03200462v1
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Thirtieth Anniversary of the Discovery of Laxaphycins. Intriguing Peptides Keeping a Part of Their Mystery

Laurine Darcel , Sanjit Das , Isabelle Bonnard , Bernard Banaigs , Nicolas Inguimbert
Marine drugs, 2021, 19 (9), pp.473. ⟨10.3390/md19090473⟩
Article dans une revue hal-03663487v1
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Insights into the Natural Defenses of a Coral Reef Fish Against Gill Ectoparasites: Integrated Metabolome and Microbiome Approach

Miriam Reverter , Pierre Sasal , Marcelino Suzuki , Delphine Raviglione , Nicolas Inguimbert
Metabolites, 2020, 10 (6), pp.227. ⟨10.3390/metabo10060227⟩
Article dans une revue hal-02994658v1
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Biological Activities of Cyclic and Acyclic B-Type Laxaphycins in SH-SY5Y Human Neuroblastoma Cells

Rebeca Alvariño , Eva Alonso , Louis Bornancin , Isabelle Bonnard , Nicolas Inguimbert
Marine drugs, 2020, 18 (7), pp.364. ⟨10.3390/md18070364⟩
Article dans une revue hal-02919925v1

Fe(III)-DOTA/Fe(III)-NOTA Complexes: Attractive Alternative Markers for Future Electrochemical Biosensors

Michel Gaillard , Hussein Kanso , Franck Denat , Carole Calas-Blanchard , Nicolas Inguimbert
Journal of The Electrochemical Society, 2020, 167 (11), pp.117502. ⟨10.1149/1945-7111/ab9e80⟩
Article dans une revue hal-03213493v1

Photodegradation of Myrigalone A, an Allelochemical from Myrica gale : Photoproducts and Effect of Terpenes

Amina Khaled , Mohamad Sleiman , Etienne Darras , Aurélien Trivella , Cédric Bertrand
Journal of Agricultural and Food Chemistry, 2019, 67 (26), pp.7258-7265. ⟨10.1021/acs.jafc.9b01722⟩
Article dans une revue hal-02190351v1

Salen/salan metallic complexes as redox labels for electrochemical aptasensors

Amani Ben Jrad , Hussein Kanso , Delphine Raviglione , Thierry Noguer , Nicolas Inguimbert
Chemical Communications, 2019, 55 (85), pp.12821-12824. ⟨10.1039/c9cc07575e⟩
Article dans une revue hal-02376397v1

Trichormamide C Structural Confirmation through Total Synthesis and Extension to Analogs

Laurine Darcel , Mahamadou Djibo , Michel Gaillard , Delphine Raviglione , Isabelle Bonnard
Organic Letters, 2019, 22 (1), pp.145-149. ⟨10.1021/acs.orglett.9b04064⟩
Article dans une revue hal-02473884v1
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Structure and biological evaluation of new cyclic and acyclic laxaphycin-A type peptides

Louis Bornancin , Eva Alonso , Rebeca Alvariño , Nicolas Inguimbert , Isabelle Bonnard
Bioorganic and Medicinal Chemistry, 2019, 27 (10), pp.1966-1980. ⟨10.1016/j.bmc.2019.03.046⟩
Article dans une revue hal-02130429v1

NI956/QGC006, a Potent Orally Active, Brain-Penetrating Aminopeptidase A Inhibitor for Treating Hypertension

Mathilde Keck , Hugo de Almeida , Delphine Compère , Nicolas Inguimbert , Adrien Flahault
Hypertension, 2019, 73 (6), pp.1300-1307. ⟨10.1161/HYPERTENSIONAHA.118.12499⟩
Article dans une revue hal-02265480v1
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Enhancing the Antimicrobial Activity of Alamethicin F50/5 by Incorporating N-terminal Hydrophobic Triazole Substituents.

Sanjit Das , Khoubaib Ben haj salah , Emmanuel Wenger , Jean Martinez , Jules Kotarba
Chemistry - A European Journal, 2017, 23 (71), pp.17964-17972. ⟨10.1002/chem.201703569⟩
Article dans une revue hal-03596125v1

Chemiluminescence immunoassays for estradiol and ethinylestradiol based on new biotinylated estrogen derivatives

Hussein Kanso , Nicolas Inguimbert , Georges Istamboulie , Lise Barthelmebs , Carole Calas-Blanchard
Analytical Biochemistry, 2017, 537, pp.63 - 68. ⟨10.1016/j.ab.2017.08.023⟩
Article dans une revue hal-01770955v1

Development and validation of LC–MS methods for peptaibol quantification in fungal extracts according to their lengths

Anne-Isaline van Bohemen , Aurore Zalouk-Vergnoux , Laurence Poirier , Nam Ngoc Phuong , Nicolas Inguimbert
Journal of Chromatography B Biomedical Sciences and Applications, 2016, 1009-1010, pp.Pages 25-33. ⟨10.1016/j.jchromb.2015.11.039⟩
Article dans une revue hal-03596091v1

A Straightforward Strategy to Substitute Amide Bonds by 1,2,3 Triazoles in Peptaibols Analogs Using Aibψ[Tz]-Xaa Dipeptides

Khoubaib Ben Haj Salah , Baptiste Legrand , Sanjit Das , Jean Martinez , Nicolas Inguimbert
Biopolymers, 2015, http://onlinelibrary.wiley.com/doi/10.1002/bip.22641/abstract. ⟨10.1002/bip.22641⟩
Article dans une revue hal-01140841v1

A new family of 1,2,5-thiadiazolidine 1,1-dioxides: Synthesis, structure and antibacterial activity

A. Amira , H. K’tir , I. Becheker , S. Ouarna , Nicolas Inguimbert
Der pharma chemica, 2015, 7 (7), pp.ePUB
Article dans une revue hal-01197166v1

Access to α,α-Disubstituted Disilylated Amino Acids and Their Use in Solid-Phase Peptide Synthesis

Roberto Fanelli , Khoubaib Ben Haj Salah , Nicolas Inguimbert , Claude Didierjean , Jean Martinez
Organic Letters, 2015, 17 (18), ⟨10.1021/acs.orglett.5b02175⟩
Article dans une revue hal-01212249v1

Synthesis, Characterization and Antibacterial Activity of Cyclic Sulfamide Linked to Tetrathiafulvalene (TTF)

Didier Villemin , Tahar Abbaz , Amel Bendjeddou , Abdelkrim Gouasmia , Djamel Bouchouk
Letters in Organic Chemistry, 2014, 11 (1), pp.59 - 63. ⟨10.2174/157017861101140113162502⟩
Article dans une revue hal-01829448v1

Targeting VEGFR1 on endothelial progenitors modulates their differentiation potential

Clément D’audigier , Benoit Gautier , Alexis Yon , Jean-Meidi Alili , Coralie L. Guérin
Angiogenesis, 2014, 17 (3), p. 603-616. ⟨10.1007/s10456-013-9413-2⟩
Article dans une revue hal-01300965v1

Synthesis, characterization and antibacterial activity of cyclic sulfamide linked to tetrathiafulvalene (TTF)

T. Abbaz , Amel Bendjeddou , Abdelkrim Gouasmia , Djamel Bouchouk , Chahinez Boualleg
Letters in Organic Chemistry, 2014, 11, pp.59-63
Article dans une revue hal-01100912v1

Efficient Microwave-Assisted One Shot Synthesis of Peptaibols Using Inexpensive Coupling Reagents

Khoubaib Ben Haj Salah , Nicolas Inguimbert
Organic Letters, 2014, 16 (6), pp.1783-1785. ⟨10.1021/ol5003253⟩
Article dans une revue hal-01140846v1

First total synthesis and stereochemical revision of laxaphycin B and its extension to lyngbyacyclamide A.

France Boyaud , Zahia Mahiout , Christine Lenoir , Shoubin Tang , Joanna Wdzieczak-Bakala
Organic Letters, 2013, 15 (15), pp.3898-901. ⟨10.1021/ol401645m⟩
Article dans une revue hal-00910980v1

Characterization of a New Anticancer Agent, EAPB0203, and Its Main Metabolites: Nuclear Magnetic Resonance and Liquid Chromatography−Mass Spectrometry Studies

Florian Lafaille , Bernard Banaigs , Nicolas Inguimbert , Christine Enjalbal , Pierre-Emmanuel Doulain
Analytical Chemistry, 2012, 84, pp.9865-9872. ⟨10.1021/ac3021483⟩
Article dans une revue hal-00771372v1

Orally active aminopeptidase A inhibitors reduce blood pressure: a new strategy for treating hypertension.

Laurence Bodineau , Alain Frugière , Yannick Marc , Nicolas Inguimbert , Céline Fassot
Hypertension, 2008, 51 (5), pp.1318-25. ⟨10.1161/HYPERTENSIONAHA.107.098772⟩
Article dans une revue inserm-00422685v1
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Asp-218 participates with asp-213 to bind a ca2+ atom into the S1 subsite of aminopeptidase A: a key element for substrate specificity

Cédric Claperon , Raphael Rozenfeld , Xavier Iturrioz , Nicolas Inguimbert , Mayumi Okada
Biochemical Journal, 2008, 416 (1), pp.37-46. ⟨10.1042/BJ20080471⟩
Article dans une revue hal-00478991v1

On-resin cyclization of peptide ligands of the Vascular Endothelial Growth Factor Receptor 1 by copper(I)-catalyzed 1,3-dipolar azide–alkyne cycloaddition

Victor Goncalves , Benoît Gautier , Anne Regazzetti , Pascale Coric , Serge Bouaziz
Bioorganic and Medicinal Chemistry Letters, 2007, 17 (20), pp.5590-5594. ⟨10.1016/j.bmcl.2007.07.087⟩
Article dans une revue hal-02122521v1

Rational Design, Structure, and Biological Evaluation of Cyclic Peptides Mimicking the Vascular Endothelial Growth Factor

Victor Goncalves , Benoît Gautier , Pascale Coric , Serge Bouaziz , Christine Lenoir
Journal of Medicinal Chemistry, 2007, 50 (21), pp.5135-5146. ⟨10.1021/jm0706970⟩
Article dans une revue hal-02122518v1

Unexpected formation of new chiral 3-amino-5-alkyl-2,5-dihydro-1H-pyrrolin-2-ones from N-Boc-α-amino esters

Nicolas Inguimbert , Hélène Dhotel , Pascale Coric , Bernard P. Roques
Tetrahedron Letters, 2005, 46 (20), pp.3517-3520. ⟨10.1016/j.tetlet.2005.03.067⟩
Article dans une revue hal-02461306v1

Synthesis and separation of tritiated inhibitors of aminopeptidase A and their prodrugs

Nicolas Inguimbert , Pascale Coric , Hélène Dhotel , Catherine Llorens-Cortès , Marie-Claude Fournie-Zaluski
Journal of Labelled Compounds and Radiopharmaceuticals, 2004, 47 (13), pp.997-1005. ⟨10.1002/jlcr.888⟩
Article dans une revue hal-02461363v1

Toward an optimal joint recognition of the S1' subsites of endothelin converting enzyme-1 (ECE-1), angiotensin converting enzyme (ACE), and neutral endopeptidase (NEP).

Nicolas Inguimbert , Pascale Coric , Hervé Poras , Hervé Meudal , Franck Teffot
Journal of Medicinal Chemistry, 2002, 45 (7), pp.1477-86
Article dans une revue hal-02122182v1
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Exploration of the S'1 subsite of neprilysin: a joined molecular modeling and site-directed mutagenesis study.

Cynthia Marie-Claire , Gilles Tiraboschi , Emmanuel Ruffet , Nicolas Inguimbert , Marie-Claude Fournie-Zaluski
Proteins - Structure, Function and Bioinformatics, 2000, 39 (4), pp.365-71
Article dans une revue inserm-00171018v1

20 000 molécules sous les mers et Invisible sous les toxines

Nicolas Inguimbert
Laetitia Hédouin. Étonnants récifs. Les écosystèmes coralliens, CNRS Editions, 2021, 978-2271139092
Chapitre d'ouvrage hal-03663520v1

Marine peptide secondary metabolites

Bernard Banaigs , Isabelle Bonnard , Anne Witczak , Nicolas Inguimbert
Stéphane La Barre; Jean-Michel Kornprobst. Outstanding Marine Molecules: Chemistry, Biology, Analysis, Wiley-VCH Verlag GmbH & Co, p. 285-318, 2014, 9783527681501. ⟨10.1002/9783527681501.ch13⟩
Chapitre d'ouvrage hal-01301162v1

S’adapter à un milieu toxique : l’exemple du lièvre de mer

Nicolas Inguimbert
50 ans du CRIOBE, CRIOBE, Jun 2021, Perpignan, France
Communication dans un congrès hal-03663501v1