Nicolas JAULIN

Nicolas JAULIN
17
Documents
Affiliations actuelles
  • Laboratoire de Thérapie Génique Translationnelle des Maladies Génétiques / Translational Research in Gene Therapy - UMR_S 1089 (TARGET)
  • Centre Hospitalier Universitaire de Nantes = Nantes University Hospital (CHU Nantes)
Identifiants chercheurs
Contact

Présentation

Domaines de recherche

Sciences du Vivant [q-bio]

Compétences

Flow cytometry ELISA ELISpot Fluorospot Cell isolation Cell sorting

Publications

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Publications

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Advancing liver gene therapy: Enhanced transduction with GalNAc-bioconjugated rAAV capsids

Pierre-Alban Lalys , Audrey Bourdon , Mohammed Bouzelha , Dimitri Alvarez-Dorta , Karine Pavageau et al.

Biomedicine and Pharmacotherapy, 2025, 189, pp.118300. ⟨10.1016/j.biopha.2025.118300⟩

Article dans une revue hal-05263420v1
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Prevalence Study of Cellular Capsid-Specific Immune Responses to AAV2, 4, 5, 8, 9, and rh10 in Healthy Donors

Rebecca Xicluna , Allan Avenel , Céline Vandamme , Marie Devaux , Nicolas Jaulin et al.

Human Gene Therapy, 2024, 35 (9-10), pp.355-364. ⟨10.1089/hum.2023.225⟩

Article dans une revue hal-04809731v1
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Transcriptomic Analysis Reveals the Inability of Recombinant AAV8 to Activate Human Monocyte-Derived Dendritic Cells

Samer Masri , Laure Carré , Nicolas Jaulin , Céline Vandamme , Célia Couzinié et al.

International Journal of Molecular Sciences, 2023, 24 (13), pp.10447. ⟨10.3390/ijms241310447⟩

Article dans une revue hal-04193929v1
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AAV8 locoregional delivery induces long-term expression of an immunogenic transgene in macaques despite persisting local inflammation

Gwladys Gernoux , Mickaël Guilbaud , Marie Devaux , Malo Journou , Virginie Pichard et al.

Molecular Therapy - Methods and Clinical Development, 2021, 20, pp.660 - 674. ⟨10.1016/j.omtm.2021.02.003⟩

Article dans une revue inserm-03172941v1
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Tetramer-Based Enrichment of Preexisting Anti-AAV8 CD8 + T Cells in Human Donors Allows the Detection of a T EMRA Subpopulation

Celine Vandamme , Rebecca Xicluna , Leslie Hesnard , Marie Devaux , Nicolas Jaulin et al.

Frontiers in Immunology, 2020, 10, pp.3110. ⟨10.3389/fimmu.2019.03110⟩

Article dans une revue inserm-02447186v1

5 years of successful inducible transgene expression following locoregional AAV delivery in nonhuman primates with no detectable immunity

Mickaël Guilbaud , Marie Devaux , Célia Couzinié , Johanne Le Duff , Alice Toromanoff et al.

Human Gene Therapy, 2019

Article dans une revue inserm-02052292v1
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Cross-Packaging and Capsid Mosaic Formation in Multiplexed AAV Libraries

Pauline F Schmit , Simon Pacouret , Eric Zinn , Elizabeth Telford , Fotini Nicolaou et al.

Molecular Therapy - Methods and Clinical Development, 2019, 17, pp.107-121. ⟨10.1016/j.omtm.2019.11.014⟩

Article dans une revue inserm-02448091v1
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Vascular Delivery of Allogeneic MuStem Cells in Dystrophic Dogs Requires Only Short-Term Immunosuppression to Avoid Host Immunity and Generate Clinical/Tissue Benefits

Judith Lorant , Thibaut Larcher , Nicolas Jaulin , Benoit Hedan , Aurélie Lardenois et al.

Cell Transplantation, 2018, 27 (7), pp.1096-1110. ⟨10.1177/0963689718776306⟩

Article dans une revue hal-01812518v1
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Early Interaction of Adeno-Associated Virus Serotype 8 Vector with the Host Immune System Following Intramuscular Delivery Results in Weak but Detectable Lymphocyte and Dendritic Cell Transduction

Gwladys Gernoux , Mickaël Guilbaud , Laurence Dubreil , Thibaut Larcher , Candice Babarit et al.

Human Gene Therapy, 2015, 26 (1), pp.1 - 13. ⟨10.1089/hum.2014.070⟩

Article dans une revue inserm-01734763v1
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Generation and in vivo evaluation of IL10-treated dendritic cells in a nonhuman primate model of AAV-based gene transfer.

Aurélie Moreau , Céline Vandamme , Mercedes Segovia , Marie Devaux , Mickaël Guilbaud et al.

Molecular Therapy - Methods and Clinical Development, 2014, 1, ⟨10.1038/mtm.2014.28⟩

Article dans une revue hal-01222897v1

Locoregional intravenous delivery of AAV vector in macaque results in persistent transgene expression despite a dedicated humoral and cellular immune responses

Gwladys Gernoux , Marie Devaux , Laurence Dubreil , Nicolas Jaulin , Mickaël Guilbaud et al.

16. Annual Meeting of the American Society of Gene and Cell Therapy (ASGCT), May 2013, Salt Lake City, Utah, United States

Communication dans un congrès hal-02749165v1

Macaque immune responses following AAV-based gene transfer to the skeletal muscle: addressing the method of vector delivery

Gwladys Gernoux , Marie Devaux , Laurence Dubreil , Nicolas Jaulin , Mickaël Guilbaud et al.

European Society of Gene and Cell Therapy/French Society of Cell and Gene Therapy Collaborative Congress, Oct 2012, Versailles, France

Communication dans un congrès hal-02747277v1

Human MuStem cells: a cell-based therapy candidate for Duchenne Muscular Dystrophy, with immunomodulatory properties.

Judith Lorant , Nicolas Jaulin , Isabelle Leroux , Céline Zuber , Cindy Schleder et al.

5th International congress of Myology, 2016, Lyon, France. 2016

Poster de conférence hal-02740840v1

Human MuStem cells, a promising therapeutic candidate for muscular dystrophies with immunomodulatory properties

Judith Lorant , Nicolas Jaulin , Marine Charrier , Blandine Lieubeau-Teillet , Isabelle Leroux et al.

Nantes Actualités Transplantation, Jun 2016, Nantes, France. 2016

Poster de conférence hal-01595625v1
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Immunomodulatory properties of human MuStem cells: assessing their impact on adaptive and innate immunity

Judith Lorant , Nicolas Jaulin , Isabelle Leroux , Cindy Schleder , Céline Zuber et al.

ESGCT and FSGT Collaborative Congress, Sep 2015, Helsinki, Finland. Human Gene Therapy, 26 (10), 2015, Human Gene Therapy

Poster de conférence hal-01242346v1

<em>In vitro</em> and <em>in vivo</em> characterization of immunomodulatory properties of MuStem cells

Judith Lorant , Nicolas Jaulin , Thibaut T. Larcher , Benoît Hédan , Jack-Yves Deschamps et al.

Annual Congress of the European Society of Gene and Cell Therapy (ESGCT), Oct 2014, The Hague, Netherlands. 2014

Poster de conférence hal-02742740v1
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Locoregional intravenous delivery of AAV vector in macaque results in persistent transgene expression despite a dedicated humoral and cellular immune response

Gwaldys Gernoux , Marie Devaux , Laurence Dubreil , Nicolas Jaulin , Mickaël Guilbaud et al.

16th annual meeting, May 2013, Salt Lake City, United States. 2013

Poster de conférence hal-01190314v1