Nicolas Reynoird

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Publications

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Cytoskeleton remodeling induced by SMYD2 methyltransferase drives breast cancer metastasis

Alexandre Casanova , Gael Roth , Simone Hausmann , Xiaoyin Lu , Ludivine Bischoff et al.

Cell Discovery, 2024, 10 (1), pp.12. ⟨10.1038/s41421-023-00644-x⟩

Article dans une revue hal-04245506v1
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Methylation of ESCRT-III components regulates the timing of cytokinetic abscission

Aurélie Richard , Jérémy Berthelet , Delphine Judith , Tamara Advedissian , Javier Espadas et al.

Nature Communications, 2024, 15 (1), pp.4023. ⟨10.1038/s41467-024-47717-3⟩

Article dans une revue pasteur-04703348v1

Natural and Synthetic Anticancer Epidrugs Targeting the Epigenetic Integrator UHRF1

Waseem Ashraf , Tanveer Ahmad , Nicolas Reynoird , Ali Hamiche , Yves Mély et al.

Molecules, 2023, 28 (16), pp.5997. ⟨10.3390/molecules28165997⟩

Article dans une revue (article de synthèse) hal-04245609v1
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The SMYD3-MAP3K2 signaling axis promotes tumor aggressiveness and metastasis in prostate cancer

Sabeen Ikram , Apurv Rege , Maraki Y Negesse , Alexandre G Casanova , Nicolas Reynoird et al.

Science Advances , 2023, 9 (46), pp.eadi5921. ⟨10.1126/sciadv.adi5921⟩

Article dans une revue hal-04727403v1
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NUT Is a Driver of p300-Mediated Histone Hyperacetylation: From Spermatogenesis to Cancer

Sophie Rousseaux , Nicolas Reynoird , Saadi Khochbin

Cancers, 2022, 14 (9), pp.2234. ⟨10.3390/cancers14092234⟩

Article dans une revue hal-03759791v1
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SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk

Valentina Lukinović , Simone Hausmann , Gael S Roth , Clement Oyeniran , Tanveer Ahmad et al.

Cancer Discovery, 2022, 12 (9), pp.2158-2179. ⟨10.1158/2159-8290.CD-21-0205⟩

Article dans une revue hal-03759864v1

Structural insights into p300 regulation and acetylation-dependent genome organisation

Ziad Ibrahim , Tao Wang , Olivier Destaing , Nicola Salvi , Naghmeh Hoghoughi et al.

Nature Communications, 2022, 13 (1), pp.7759. ⟨10.1038/s41467-022-35375-2⟩

Article dans une revue hal-04245616v1
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Aberrant RNA methylation triggers recruitment of an alkylation repair complex

Ning Tsao , Joshua R Brickner , Rebecca Rodell , Adit Ganguly , Matthew Wood et al.

Molecular Cell, 2021, 81 (20), pp.4228-4242.e8. ⟨10.1016/j.molcel.2021.09.024⟩

Article dans une revue hal-03759772v1
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Lysine Methyltransferases Signaling: Histones are Just the Tip of the Iceberg

Valentina Lukinović , Alexandre Casanova , Gael S Roth , Florent Chuffart , Nicolas Reynoird

Current Protein and Peptide Science, 2020, 21 (7), pp.655-674. ⟨10.2174/1871527319666200102101608⟩

Article dans une revue hal-02989776v1
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Nut Directs p300-Dependent, Genome-Wide H4 Hyperacetylation in Male Germ Cells

Hitoshi Shiota , Sophie Barral , Thierry Buchou , Minjia Tan , Yohann Couté et al.

Cell Reports, 2018, 24 (13), pp.3477 - 3487.e6. ⟨10.1016/j.celrep.2018.08.069⟩

Article dans une revue hal-01887337v1

Lysine methylation signaling in pancreatic cancer

Gaël Roth , Alexandre Casanova , Nathanaël Lemonnier , Nicolas Reynoird

Current Opinion in Oncology, 2018, 30 (1), pp.30-37. ⟨10.1097/CCO.0000000000000421⟩

Article dans une revue hal-02989788v1

Bromodomain factors of BET family are new essential actors of pericentric heterochromatin transcriptional activation in response to heat shock

Edwige Col , Neda Hoghoughi , Solenne Dufour , Jessica Penin , Sivan Koskas et al.

Scientific Reports, 2017, 7 (1), pp.5418. ⟨10.1038/s41598-017-05343-8⟩

Article dans une revue hal-04980603v1
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Bromodomain factors of BET family are new essential actors of pericentric heterochromatin transcriptional activation in response to heat shock

Edwige Col , Neda Hoghoughi , Solenne Dufour , Jessica Penin , Sivan Koskas et al.

Scientific Reports, 2017, 7, pp.5418. ⟨10.1038/s41598-017-05343-8⟩

Article dans une revue hal-02989794v1

Novel insights into the oncogenic function of the SMYD3 lysine methyltransferase

Pawel Mazur , Or Gozani , Julien Sage , Nicolas Reynoird

Translational Cancer Research, 2016, 5 (3), pp.330-333. ⟨10.21037/tcr.2016.06.26⟩

Article dans une revue hal-02989799v1
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Coordination of stress signals by the lysine methyltransferase SMYD2 promotes pancreatic cancer

Nicolas Reynoird , Pawel Mazur , Timo Stellfeld , Natasha Flores , Shane Lofgren et al.

Genes and Development, 2016, 30 (7), pp.772-785. ⟨10.1101/gad.275529.115⟩

Article dans une revue hal-02989803v1

A Proteomic Strategy Identifies Lysine Methylation of Splicing Factor snRNP70 by the SETMAR Enzyme

Scott Carlson , Kaitlyn Moore , Saumya Sankaran , Nicolas Reynoird , Joshua Elias et al.

Journal of Biological Chemistry, 2015, 290 (19), pp.12040-12047. ⟨10.1074/jbc.M115.641530⟩

Article dans une revue hal-02989808v1

Nuclear PI5P, Uhrf1, and the Road Not Taken

Nicolas Reynoird , Or Gozani

Molecular Cell, 2014, 54 (6), pp.901-903. ⟨10.1016/j.molcel.2014.06.012⟩

Article dans une revue hal-02989812v1

SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer

Pawel Mazur , Nicolas Reynoird , Purvesh Khatri , Pascal Jansen , Alex Wilkinson et al.

Nature, 2014, 510 (7504), pp.283-287. ⟨10.1038/nature13320⟩

Article dans une revue hal-02989816v1

Smyd3 regulates cancer cell phenotypes and catalyzes histone H4 lysine 5 methylation

Glenn van Aller , Nicolas Reynoird , Olena Barbash , Michael Huddleston , Shichong Liu et al.

Epigenetics, 2012, 7 (4), pp.340-343. ⟨10.4161/epi.19506⟩

Article dans une revue hal-02989821v1

Molecular models for post-meiotic male genome reprogramming

Sophie Rousseaux , Fayçal Boussouar , Jonathan Gaucher , Nicolas Reynoird , Emilie Montellier et al.

Systems Biology in Reproductive Medicine, 2011, 57 (1-2), pp.50-53. ⟨10.3109/19396368.2010.498076⟩

Article dans une revue hal-05281279v1

Oncogenesis by sequestration of CBP/p300 in transcriptionally inactive hyperacetylated chromatin domains

Nicolas Reynoird , Brian Schwartz , Manuela Delvecchio , Karin Sadoul , David Meyers et al.

EMBO Journal, 2010, 29 (17), pp.2943-2952. ⟨10.1038/emboj.2010.176⟩

Article dans une revue hal-02989825v1

From meiosis to postmeiotic events: The secrets of histone disappearance

Jonathan Gaucher , Nicolas Reynoird , Emilie Montellier , Fayçal Boussouar , Sophie Rousseaux et al.

FEBS Journal, 2010, 277 (3), pp.599-604. ⟨10.1111/j.1742-4658.2009.07504.x⟩

Article dans une revue hal-05281286v1