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Nicolas Savy

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Publications

Agent based modeling in health care economics: examples in the field of thyroid cancer

Romain Demeulemeester , Nicolas Savy , Pascale Grosclaude , Nadège Costa , Philippe Saint-Pierre
The international journal of biostatistics, 2023, 19 (2), pp.351-368. ⟨10.1515/ijb-2022-0107⟩
Journal articles hal-04474992v1
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OTrecod: An R Package for Data Fusion using Optimal Transportation Theory

Grégory Guernec , Valérie Garès , Jérémy Omer , Nicolas Savy , Philippe Saint-Pierre
R Journal, 2022, 14 (4), pp.195 - 222. ⟨10.32614/RJ-2023-006⟩
Journal articles hal-03827398v1
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Équiper et évaluer un « certificat de compétences cliniques »

Olivier Catteau , Anne Mayère , Nicolas Savy , Odile Beyne-Rauzy
STICEF (Sciences et Technologies de l'Information et de la Communication pour l'Éducation et la Formation), 2021, Numéro Spécial - Sélection de la conférence EIAH 2019, 27 (2), pp.1-28. ⟨10.23709/sticef.27.2.1⟩
Journal articles hal-03186732v1
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Guiding measurement protocols of connected medical devices using digital twins: A statistical methodology applied to detecting and monitoring lymphedema

Loic Bethencourt , Walid Dabachine , Vincent Dejouy , Zakaria Lalmiche , Karl Neuberger
IEEE Access, 2021, Online ahead of print. ⟨10.1109/ACCESS.2021.3063786⟩
Journal articles inserm-03167145v1

La fabrique des données à l’épreuve des programmes de big data

Nicolas Savy , Anne Mayère , Anja Martin-Scholz , François Lambotte
Actualité et dossier en santé publique, 2020, Dossier thématique Données massives et santé publique, 112, pp.27-29
Journal articles hal-03352270v1
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Real-world costs of illness of Hodgkin and the main B-Cell Non-Hodgkin lymphomas in France

Michael Mounie , Nadège Costa , Cécile Conte , Dominique Petiot , Didier Fabre
Journal of Medical Economics, 2020, 23 (3), pp.235-242. ⟨10.1080/13696998.2019.1702990⟩
Journal articles hal-02533775v1
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On the use of optimal transportation theory to recode variables and application to database merging

Valérie Garès , Chloé Dimeglio , Grégory Guernec , Romain Fantin , Benoit Lepage
The international journal of biostatistics, 2020, 16 (1), pp.article number : 20180106. ⟨10.1515/ijb-2018-0106⟩
Journal articles hal-01905857v2
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The GMO90+ Project: Absence of Evidence for Biologically Meaningful Effects of Genetically Modified Maize-based Diets on Wistar Rats After 6-Months Feeding Comparative Trial

Xavier Coumoul , Rémi Servien , Ludmila Juricek , Yael Kaddouch-Amar , Yannick Lippi
Toxicological Sciences, 2019, 168 (2), pp.315-338. ⟨10.1093/toxsci/kfy298⟩
Journal articles hal-02196332v1

Incremental Costs in Giant Cell Arteritis

Michael Mounié , Nadège Costa , Laurent Sailler , Maryse Lapeyre-Mestre , Robert Bourrel
Arthritis Care & Research = Arthritis Care and Research, 2018, 70 (7), pp.1074 - 1081. ⟨10.1002/acr.23429⟩
Journal articles hal-01864221v1

Évaluation du coût de la prise en charge des patients atteints de Leucémie Myéloïde Chronique (LMC) en Midi-Pyrénées : impact économique des différents Inhibiteurs de Protéines Kinases

Michael Mounié , Nadège Costa , Martin Gauthier , Aurore Palmaro , Cyrille Delpierre
Journal de gestion et d’économie médicales, 2018, 36 (2), pp.109
Journal articles hal-01976692v1

Stopping or maintaining oral anticoagulation in patients undergoing photoselective vaporization of the prostate (SOAP) surgery for benign prostate obstruction: study protocol for a multicentre randomized controlled trial

Hélène Charbonneau , Marie Pasquié , Benoit Peyronnet , Aurélien Descazeaud , Nicolas Barry-Delongchamps
Trials, 2018, 19 (1), ⟨10.1186/s13063-018-3066-9⟩
Journal articles hal-02180512v1

Anticipative Integrals with respect to a filtered Lévy Process and Lévy-Itô decomposition

Nicolas Savy , Josep Vives
Communications on Stochastic Analysis, 2017, 11 (1), pp.63-85
Journal articles hal-01864321v1

On the Fleming-Harrington test for late effects in prevention randomized controlled trials

Valérie Garès , Sandrine Andrieu , Jean-François Dupuy , Nicolas Savy
Journal of Statistical Theory and Practice, 2017, 11 (3), pp.418-435. ⟨10.1080/15598608.2017.1295889⟩
Journal articles hal-01539213v1

Interest of the trajectory method for the evaluation of outcomes after in utero drug exposure: example of anxiolytics and hypnotics

Caroline Hurault-Delarue , Cécile Chouquet , Nicolas Savy , Isabelle Lacroix , Anna-Belle Beau
Pharmacoepidemiology and Drug Safety, 2017, 26 (5), pp.561-569
Journal articles hal-01974892v1

The Authors Respond

Benoit Lepage , Sébastien Lamy , Nicolas Savy , Thierry Lang
Epidemiology, 2017, 28 (3), pp.e29. ⟨10.1097/EDE.0000000000000619⟩
Journal articles hal-01864253v1

Using Poisson-gamma model to evaluate the duration of recruitment process when historical trials are available

Nathan Minois , Valerie Lauwers-Cances , Stephanie Savy , Michel Attal , Sandrine Andrieu
Statistics in Medicine, 2017, 36 (23), pp.3605 - 3620. ⟨10.1002/sim.7365⟩
Journal articles hal-01864244v1

How to deal with the Poisson-gamma model to forecast patients' recruitment in clinical trials when there are pauses in recruitment dynamic?

Nathan Minois , Valerie Lauwers-Cances , Stephanie Savy , Michel Attal , Sandrine Andrieu
Contemporary Clinical Trials Communications, 2017, 5 (23), pp.144 - 152. ⟨10.1016/j.conctc.2017.01.003⟩
Journal articles hal-01864356v1

Additional costs of polymyalgia rheumatica with giant-cell arteritis

Michael Mounié , Grégory Pugnet , Nicolas Savy , Maryse Lapeyre-Mestre , Laurent Molinier
Arthritis Care & Research = Arthritis Care and Research, 2016, 11 (3), pp.418-435
Journal articles hal-01976676v1

Un vicomte rescapé, un comte retrouvé et un chevalier ruiné. Notes sur des prisonniers de la bataille de Poitiers

Françoise Lainé , Nicolas Savy
Annales du Midi : revue archéologique, historique et philologique de la France méridionale, 2016, 128 (293), pp.45-67
Journal articles hal-01477735v1

Estimation of a controlled direct effect when an effect of the exposure confounds the mediator-outcome relationship: a comparison of different methods.

Benoit Lepage , Dominique Dedieu , Nicolas Savy , Thierry Lang
Statistical Methods in Medical Research, 2016, 25 (2), pp.553-570
Journal articles hal-01864366v1

How to take into account exposure to drugs over time in pharmacoepidemiology studies of pregnant women?

Caroline Hurault-Delarue , Cécile Chouquet , Nicolas Savy , Isabelle Lacroix , Anna-Belle Beau
Pharmacoepidemiology and Drug Safety, 2016, 25 (7), pp.770 - 777. ⟨10.1002/pds.4000⟩
Journal articles hal-01864258v1

An omnibus test for several hazard alternatives in prevention randomized controlled clinical trials

Valérie Garès , Sandrine Andrieu , Jean-François Dupuy , Nicolas Savy
Statistics in Medicine, 2015, 34 (4), pp.541-557. ⟨10.1002/sim.6366⟩
Journal articles hal-01120983v1

Estimating the Causal Effect of an Exposure on Change from Baseline Using Directed Acyclic Graphs and Path Analysis

Benoit Lepage , Sébastien Lamy , Dominique Dedieu , Nicolas Savy , Thierry Lang
Epidemiology, 2015, 26 (1), pp.122 - 129. ⟨10.1097/EDE.0000000000000192⟩
Journal articles hal-01864260v1

Big Data et Santé publique : plus que jamais, les enjeux de la connaissance

Chloé Dimeglio , Cyrille Delpierre , Nicolas Savy , Thierry Lang
Actualité et dossier en santé publique, 2015, 93, pp.5-7
Journal articles hal-01864348v1
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On Ornstein-Uhlenbeck driven by Ornstein-Uhlenbeck processes

Bernard Bercu , Frédéric Proïa , Nicolas Savy
Statistics and Probability Letters, 2014, 85, pp.36-44. ⟨10.1016/j.spl.2013.11.002⟩
Journal articles hal-00915963v1

A comparison of the constant piecewise weighted logrank and Fleming-Harrington tests

Valérie Garès , Sandrine Andrieu , Jean-François Dupuy , Nicolas Savy
Electronic Journal of Statistics , 2014, 8, pp.841-860. ⟨10.2014/14-EJS911⟩
Journal articles hal-01056360v1

Mixed Hidden Markov Model for Heterogeneous Longitudinal Data with Missingness and Errors in the Outcome Variable

Dominique Dedieu , Cyrille Delpierre , Sébastien Gadat , Thierry Lang , Benoit Lepage
Journal de la Société Française de Statistique, 2014, 105 (1), pp.73-98
Journal articles hal-01864353v1

Deleterious impact of feto-maternal MHC compatibility on the success of pregnancy in a macaque model

Alice Aarnink , Edward Mee , Nicolas Savy , Nicola Congy-Jolivet , Nicola Rose
Immunogenetics, inPress, 66 (2), pp.105 - 113. ⟨10.1007/s00251-013-0752-3⟩
Journal articles hal-01864282v1

Estimation of the instantaneous volatility

Alexander Alvarez , Fabien Panloup , Monique Pontier , Nicolas Savy
Statistical Inference for Stochastic Processes, 2012, 15 (1), pp.27-59. ⟨10.1007/s11203-011-9062-2⟩
Journal articles hal-00761710v1

Models for patients' recruitment in clinical trials and sensitivity analysis

Guillaume Mijoule , Stéphanie Savy , Nicolas Savy
Statistics in Medicine, 2012, 31 (16), pp.1655-1674. ⟨10.1002/sim.4495⟩
Journal articles hal-00942867v1
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Sharp large deviations for the non-stationary Ornstein-Uhlenbeck process

Bernard Bercu , Laure Coutin , Nicolas Savy
Stochastic Processes and their Applications, 2012, 122, pp.3393-3424. ⟨10.1016/j.spa.2012.06.006⟩
Journal articles hal-00645074v1

Use of Cumulative Poisson Probability Distribution as an Estimator of the Recombination Rate in an Expanding Population: Example of the Macaca fascicularis Major Histocompatibility Complex

Antoine Blancher , Alice Aarnink , Nicolas Savy , Naoyuki Takahata
G3, 2012, 2, pp.123-130. ⟨10.1534/g3.111.001248⟩
Journal articles hal-01864345v1

Sharp large deviations for the fractional Ornstein-Uhlenbeck process

Bernard Bercu , Laure Coutin , Nicolas Savy
SIAM Theory of Probability and its Applications, 2011, 55 (4), pp.575-610
Journal articles hal-00386239v1

Sharp large deviations for the fractional Ornstein - Uhlenbeck process

Bernard Bercu , Laure Coutin , Nicolas Savy
Teoriya Veroyatnostei i ee Primeneniya, 2010, 55 (4), pp.732-771
Journal articles hal-01976746v1
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Upper bounds on Rubinstein distances on configuration spaces and applications

Laurent Decreusefond , Aldéric Joulin , Nicolas Savy
Communications on Stochastic Analysis, 2010, 4 (3), pp.377--399
Journal articles hal-00347899v2

Anticipative calculus with respect to filtered Poisson processes

L. Decreusefond , Nicolas Savy
Annales de l'Institut Henri Poincaré (B) Probabilités et Statistiques, 2006, 42 (3), pp.343 - 372. ⟨10.1016/j.anihpb.2005.03.005⟩
Journal articles hal-01864331v1
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A general model based on two mixed Weibull distributions of bacterial resistance, for fitting various shapes of inactivation curves

Louis Coroller , Ivan Leguérinel , Eric Mettler , Nicolas Savy , Pierre Mafart
Applied and Environmental Microbiology, 2006, 72 (10), pp.6493-6502. ⟨10.1128/AEM.00876-06⟩
Journal articles hal-00552093v1
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Filtered Brownian motions as weak limit of filtered Poisson processes

L. Decreusefond , Nicolas Savy
Bernoulli, 2005, 11 (2), pp.283-292
Journal articles hal-00841352v1
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Quantifying the combined effects of the heating time, the temperature and the recovery medium pH on the regrowth lag time of Bacillus cereus spores after a heat treatment

Stéphane Gaillard , Ivan Leguérinel , Nicolas Savy , Pierre Mafart
International Journal of Food Microbiology, 2005, pp.1-6
Journal articles hal-00653930v1
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Survival curves of heated bacterial spores: effect of environmental factors on Weibull parameters

Olivier Couvert , Stéphane Gaillard , Nicolas Savy , Pierre Mafart , Ivan Leguérinel
International Journal of Food Microbiology, 2005, 101 (1), pp.73-81. ⟨10.1016/j.ijfoodmicro.2004.10.048⟩
Journal articles hal-00560873v1

Filtered Brownian motions as weak limit of filtered Poisson processes

Laurent Decreusefond , Nicolas Savy
Bernoulli, 2005, 11 (2), pp.283-292
Journal articles hal-01864326v1
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Classification of the evolutionary trajectories of cognitive functions

Céline Bougel , Sébastien Déjean , Caroline Giulioli , Philippe Saint-Pierre , Nicolas Savy
Journées Ouvertes Biologie, Informatique et Mathématiques (JOBIM), Jul 2019, Nantes (44000), France
Conference poster hal-04315774v1

Performances of Poisson–Gamma Model for Patients’ Recruitment in Clinical Trials When There Are Pauses in Recruitment or When the Number of Centres is Small

Nathan Minois , Guillaume Mijoule , Stéphanie Savy , Valérie Lauwers-Cances , Sandrine Andrieu
Springer Proceedings in Mathematics & Statistics book series - Statistics and Simulation - IWS 8, Vienna, Austria, September 2015, 2015
Book sections hal-01976829v1

Simulated Clinical Trials: Principle, Good Practices, and Focus on Virtual Patients Generation

Nicolas Savy , Stéphanie Savy , Sandrine Andrieu , Sebastien Marque
Springer Proceedings in Mathematics & Statistics book series - statistics and simulation - IWS 8, Vienna, Austria, September 2015, 2015
Book sections hal-01976838v1

Additive Cost Modelling in Clinical Trial

Guillaume Mijoule , Nathan Minois , Vladimir Anisimov , Nicolas Savy
Springer Proceedings in Mathematics & Statistics book series (PROMS, volume 114) -, 2014
Book sections hal-01976846v1
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Investigations on Stochastic Calculus, Statistics of Processes Applied Statistics for Biology and Medical Research

Nicolas Savy
Applications [stat.AP]. Université de Toulouse 3 Paul Sabatier, 2014
Habilitation à diriger des recherches tel-01645597v1