NICOLAS POIRIER

INRAE - Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement [France] UMR 1324 CSGA - Centre des Sciences du Goût et de l'Alimentation [Dijon]
33%
Libre accès
40
Documents
Affiliation actuelle
  • Centre des Sciences du Goût et de l'Alimentation [Dijon] (CSGA)
Identifiants chercheurs

Présentation

Thèmes de recherche Assistant ingénieur INRAE Alimentation Humaine Mes recherches portent sur les mécanismes biochimiques de la flaveur : production, purification et caractérisation de protéines et enzymes impliquées dans le goût et l’'odorat.

Activités / CV Parcours universitaire (BAC + 3) Licence professionnelle UFR Sciences Exactes et Naturelles REIMS (51).

Programmes de recherche Participe aux programmes ANR FLAMME, ANR PIVERT, ANR NOEMI / ANR MOREAROMA, ANR NEONATOLF

Identifiants externes https://orcid.org/0000-0002-7701-4289 https://scholar.google.fr/citations?user=pDnmuXIAAAAJ&hl=fr&oi=ao https://www.scopus.com/authid/detail.uri?authorId=54943267400 https://www.lens.org/lens/profile/622128163/scholar

Domaines de recherche

Sciences du Vivant [q-bio] Alimentation et Nutrition Biochimie, Biologie Moléculaire Biotechnologies

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Publications

Image document

Inosine-5′-monophosphate interacts with the TAS1R3 subunit to enhance sweet taste detection

Christine Belloir , Lucie Moitrier , Adeline Karolkowski , Nicolas Poirier , F. Neiers et al.
Food Chemistry: Molecular Sciences, 2025, 10, pp.100246. ⟨10.1016/j.fochms.2025.100246⟩
Article dans une revue hal-04958107 v1

Crystallization and Preliminary X-ray Diffraction Study of a Putative β-glycosidase from the Oral Bacteria <i>Prevotella sp.</i>

Mariam Muradova , Nicolas Poirier , Jade Moreno , Alena Proskura , F. Lirussi et al.
Crystallography Reports, 2024, 69 (4), pp.507-512. ⟨10.1134/s1063774523601442⟩
Article dans une revue hal-04737369 v1

Molecular and Cellular Characterization of the Glutathione Transferases Involved in the Olfactory Metabolism of the Mammary Pheromone

Marie-Sabelle Hjeij , Franck Ménétrier , Isabelle Chauvel , Nicolas Poirier , Stéphane Fraichard et al.
Journal of Agricultural and Food Chemistry, 2024, 72 (44), pp.24724-24735. ⟨10.1021/acs.jafc.4c07000⟩
Article dans une revue hal-04761763 v1

<i>Rattus norvegicus</i> Glutathione Transferase Omega 1 Localization in Oral Tissues and Interactions with Food Phytochemicals

Nicolas Poirier , Franck Ménétrier , Jade Moreno , Valentin Boichot , Jean-Marie Heydel et al.
Journal of Agricultural and Food Chemistry, 2024, 72 (11), pp.5887-5897. ⟨10.1021/acs.jafc.4c00483⟩
Article dans une revue hal-04493038 v1
Image document

Microbial β C-S Lyases: Enzymes with Multifaceted Roles in Flavor Generation

Mathieu Schwartz , Nicolas Poirier , Jade Moreno , Alena Proskura , Mélanie Lelièvre et al.
International Journal of Molecular Sciences, 2024, 25 (12), pp.6412. ⟨10.3390/ijms25126412⟩
Article dans une revue (article de synthèse) hal-04642563 v2
Image document

Sweet-inhibiting effects of gurmarin on intake during repeated acute and long-term sugar exposure: A behavioural analysis using an animal model

Raquel Rayo-Morales , Antonio Segura-Carretero , Nicolas Poirier , Loïc Briand , David Garcia-Burgos
Journal of Functional Foods, 2023, 108, pp.105743. ⟨10.1016/j.jff.2023.105743⟩
Article dans une revue hal-04189403 v1
Image document

Comparison of different signal peptides for the efficient secretion of the sweet-tasting plant protein brazzein in Pichia pastoris

Fabrice Neiers , Christine Belloir , Nicolas Poirier , Christian Naumer , Michael Krohn et al.
Life, 2021, 11 (1), pp.46. ⟨10.3390/life11010046⟩
Article dans une revue hal-03144294 v1

The Drosophila odorant-binding protein 28a is involved in the detection of the floral odour ß-ionone

Daniel Gonzalez , Karen Rihani , Fabrice Neiers , Nicolas Poirier , Stéphane Fraichard et al.
Cellular and Molecular Life Sciences, 2020, 77 (13), pp.2565-2577. ⟨10.1007/s00018-019-03300-4⟩
Article dans une revue hal-02384074 v1

A conserved odorant binding protein is required for essential amino acid detection in Drosophila

Karen Rihani , Stéphane Fraichard , Isabelle Chauvel , Nicolas Poirier , Thomas Delompré et al.
Communications Biology, 2019, 2 (1), pp.425. ⟨10.1038/s42003-019-0673-2⟩
Article dans une revue hal-04524928 v1
Image document

A conserved odorant binding protein is required for essential amino acid detection in Drosophila

Karen Rihani , Stéphane Fraichard , Isabelle Chauvel , Nicolas Poirier , Thomas Delompré et al.
Communications Biology, 2019, 2 (1), pp.425. ⟨10.1038/s42003-019-0673-2⟩
Article dans une revue hal-02384207 v1
Image document

The crystal structure of gurmarin, a sweet taste-suppressing protein: Identification of the amino acid residues essential for inhibition

Maud Sigoillot , Anne Brockoff , Fabrice Neiers , Nicolas Poirier , Christine Belloir et al.
Chemical Senses, 2018, 43 (8), pp.635-643. ⟨10.1093/chemse/bjy054⟩
Article dans une revue hal-02626068 v1

Optimization of the production of gurmarin, a sweet-taste-suppressing protein, secreted by the methylotrophic yeast Pichia pastoris.

Maud Sigoillot , Anne Brockhoff , Ewen Lescop , Nicolas Poirier , Wolfgang Meyerhof et al.
Applied Microbiology and Biotechnology, 2012, 96 (5), pp.1253-63. ⟨10.1007/s00253-012-3897-3⟩
Article dans une revue istex hal-00763833 v1

Efficient production and characterization of the sweet-tasting brazzein secreted by the yeast [i]Pichia pastoris[/i]

Nicolas Poirier , Natacha Roudnitzky , Anne Brockhoff , Christine Belloir , Marie Maison et al.
Journal of Agricultural and Food Chemistry, 2012, 60 (39), pp.9807 - 9814. ⟨10.1021/jf301600m⟩
Article dans une revue hal-01223562 v1
Image document

Understanding the in-mouth release of aroma sulfur compounds from food precursors and the role of microbial C-S lyases

Mathieu Schwartz , Nicolas Poirier , Jade Moreno , Francis Canon , F. Neiers
2. international Meet on food science and technology, Aug 2023, Vancouver, Canada
Communication dans un congrès hal-04464859 v1

Metabolism of flavor sulfur precursors by the oral microbiota

Mathieu Schwartz , Nicolas Poirier , Valentin Boichot , Francis Canon , F. Neiers
Food Science Meeting, May 2022, Valence, Spain
Communication dans un congrès hal-03829017 v1
Image document

In-mouth metabolism and production of flavor sulfur compounds by oral microbiota enzymes

Mathieu Schwartz , Nicolas Poirier , Karine Gourrat , Francis Canon , F. Neiers
FCT2022 International Conference on Food chemistry and Technology, Oct 2022, Rome, Italy
Communication dans un congrès hal-03986310 v1

Metabolism of flavor sulfur precursors by the oral microbiota

Mathieu Schwartz , Nicolas Poirier , Valentin Boichot , Francis Canon , F. Neiers
IATA Conference, Instituto de Agroquímica y Tecnología de Alimentos, Jun 2022, Valence, Spain
Communication dans un congrès hal-03827341 v1

Implication de l’OBP19b dans la perception gustative des acides aminés chez <em>Drosophila melanogaster</em>

Karen Rihani , Stéphane Fraichard , Thomas Delompré , Nicolas Poirier , Isabelle Chauvel et al.
Colloque ARET 2018, May 2018, Dijon, France
Communication dans un congrès hal-02790748 v1

The implication of OBP28a in <em>Drosophila melanogaster</em> chemosensory perception

Karen Rihani , Daniel Gonzalez , Fabrice Neiers , Nicolas Poirier , Stéphane Fraichard et al.
31. French Drosophila Meeting (FDM 2017), Nov 2017, Presqu'île de Giens, France
Communication dans un congrès hal-02785694 v1

Function of odorant-binding proteins in the Drosophila melanogaster chemoreception

Karen Rihani , Stéphane Fraichard , Nicolas Poirier , Thomas Delompré , Isabelle Chauvel et al.
18. rencontre du Club de neurobiologie des invertébrés, Jun 2017, Dijon, France. 1 p
Communication dans un congrès hal-01575114 v1

Ligand binding properties of OBP28a, a recombinant odorant binding protein from Drosophila melanogaster

Daniel Gonzalez , Fabrice Neiers , Nicolas Poirier , Guillaume Gotthard , Stéphane Fraichard et al.
18. rencontre du Club de neurobiologie des invertébrés, Jun 2017, Dijon, France. 1 p
Communication dans un congrès hal-01575118 v1
Image document

Role of odorant binding protein 28a in <em>Drosophila melanogaster</em> chemosensory perception

Karen Rihani , Daniel Gonzalez , Fabrice Neiers , Nicolas Poirier , Stéphane Fraichard et al.
3. Réunion Annuelle du Groupement de Recherche Odorant-Odeur-Olfaction (GDR O3), Oct 2017, Paris, France
Communication dans un congrès hal-02788727 v1

Function of odorant-binding proteins in the Drosophila melanogaster chemoreception

Karen Rihani , Stéphane Fraichard , Nicolas Poirier , Thomas Delompré , Isabelle Chauvel et al.
23. forum des Jeunes chercheurs, Jun 2017, Dijon, France. 1 p
Communication dans un congrès hal-01575113 v1

Purification and characterization of recombinant gurmarin secreted by the yeast Pichia pastoris

Maud M. Sigoillot , Nicolas Poirier , Loïc Briand
20. Congress of the european chemoreception research organisation (ECRO), Sep 2010, Avignon, France. 1 p
Communication dans un congrès hal-02748655 v1

Optimization of the production of recombinant brazzein secreted by the yeast pichia pastoris

Antoine Rachid , Christine Belloir , Joëlle Chevalier , Catherine Desmetz , Marie-Louise Miller et al.
31. annual meeting - Association for chemoreception sciences (AChemS), Apr 2009, Sarasota, Floride, United States. 1 p
Communication dans un congrès hal-02754940 v1

Role of oral bacterial glycosidases in human flavor perception

Mariam Muradova , Alena Proskura , Nicolas Poirier , Francis Canon , Jean-Marie Heydel et al.
The International Symposium on Olfaction and Taste (ISOT), Jun 2024, Reykjavík, Iceland
Poster de conférence hal-04771642 v1

Purification and functional characterization of three human salivary proline-rich proteins involved in astringency

Alena Proskura , Mariam Muradova , Nicolas Poirier , Mathieu Schwartz , Francis Canon et al.
The International Symposium on Olfaction and Taste (ISOT), Jun 2024, Reykjavík, Iceland
Poster de conférence hal-04771592 v1

Rôle du microbiote oral dans la métabolisation de divers précurseurs aromatiques soufrés

Jade Moreno , Mélanie Lelièvre , Nicolas Poirier , Francis Canon , F. Neiers et al.
PIA4 « Excellences » HARMI: HARnessing MIcrobiomes for sustainable development, Sep 2024, Dole, France
Poster de conférence hal-04771730 v1

Characterization of the glutathione transferases involved in the olfactory metabolism of the mammary pheromone

Marie-Sabelle Hjeij , Franck Ménétrier , Isabelle Chauvel , Stéphane Fraichard , Quentin Bonnin et al.
The International Symposium on Olfaction and Taste (ISOT), Jun 2024, Reykjavík, Iceland
Poster de conférence hal-04771537 v1

Strategy for recombinant expression of soluble functional N-terminal domain of human sweet taste receptor produced in Escherichia coli

Christine Belloir , Nicolas Poirier , Lucie Moitrier , Fabrice Neiers , Loïc Briand
41. annual meeting - association for chemoreception sciences (AChemS), Apr 2019, Bonita Springs, Florida, United States. Oxford University Press, Chemical Senses, 44 (7), pp.E71-E71, 2019
Poster de conférence hal-02734758 v1

OBP19b is involved in the taste perception of amino acid in Drosophila melanogaster

Karen Rihani , Stéphane Fraichard , Thomas Delompré , Nicolas Poirier , Isabelle Chauvel et al.
17. European Drosophila Neurobiology Conference (Neurofly 2018), Sep 2018, Cracovie, Poland. , 1 p., 2018
Poster de conférence hal-01857676 v1

The X-ray structure of gurmarin provide new insights into amino acid residues essential for inhibition of the rat sweet taste receptor

Maud M. Sigoillot , Anne Brockoff , Fabrice Neiers , Nicolas Poirier , Christine Belloir et al.
28. Congress of the European Chemoreception Research Organization (ECRO 2018), Sep 2018, Wurtzbourg, Germany. Oxford University Press, Chemical Senses, 44 (3), 1 p., 2019
Poster de conférence hal-02735462 v1

Odorant-binding proteins mutants having novel binding properties

Emilie Barou , Christine Belloir , Nicolas Poirier , Fabrice Neiers , Loïc Briand
26. annual meeting of the european-chemoreception-research-organization (ECRO), Sep 2016, Dijon, France. Oxford University Press, Chemical Senses, 42 (2), 1 p., 2016, Chemical Senses. ⟨10.1093/chemse/bjw120⟩
Poster de conférence hal-01523754 v1

Engineering the sweet-tasting protein brazzein: analysis the effects on stability and sensory profile

Katja Riedel , Fabrice Neiers , Christine Belloir , Isabell Giestler-Al-Madani , Silke Meinecke et al.
The 17. international symposium on Olfaction and taste (ISOT), Jun 2016, Yokohama, Japan. 1 p
Poster de conférence hal-02918213 v1

Purification, biophysical characterization and first crystallization trials of the ligand-binding domain of the human T1R3 sweet taste receptor

Fabrice Neiers , Maud M. Sigoillot , Elodie Maitrepierre , Christine Belloir , Nicolas Poirier et al.
AChemS XXXV-35th Annual Meeting of the Association for Chemoreception Sciences, Apr 2013, Huntington beach, Californie, United States. 1 p., 2013
Poster de conférence hal-02805969 v1

Overexpression of recombinant gurmarin secreted by the yeast Pichia pastoris

Maud M. Sigoillot , Nicolas Poirier , Loïc Briand
AChemS XXXIII-33rd Annual Meeting of the Association for Chemoreception Sciences, Apr 2011, St Pete Beach, Floride, United States. 1 p., 2011
Poster de conférence hal-02807184 v1

P16 - Engineering the full sequence space of the sweet-tasting protein brazzein

Katja Reidel , Fabrice Neiers , Christine Belloir , Isabell Geistler-Al-Madani , Silke Meinecke et al.
/, Chemical Senses, 45 (2), pp.147-147 (P16), 2020, ECRO 2019, ⟨10.1093/chemse/bjaa007⟩
Proceedings/Recueil des communications hal-02885491 v1

Resolution of the X-ray structure of gurmarin: new insights into the molecular mechanism of sweet taste receptor inhibition

Maud Sigoillot , Anne A. Brockhoff , Fabrice Neiers , Nicolas Poirier , Christine Belloir et al.
/, Chemical Senses, 45 (2), pp.124-124, 2020, Abstracts of the 29. annual meeting of the European-Chemoreception-Research-Organization (ECRO)
Proceedings/Recueil des communications hal-02885406 v1