NICOLAS POIRIER

INRAE - Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement [France] UBE - Université Bourgogne Europe UMR 1324 CSGA - Centre des Sciences du Goût et de l'Alimentation [Dijon]
29%
Libre accès
41
Documents
Affiliation actuelle
  • Centre des Sciences du Goût et de l'Alimentation [Dijon] (CSGA)
Identifiants chercheurs

Présentation

Thèmes de recherche Assistant ingénieur INRAE Alimentation Humaine Mes recherches portent sur les mécanismes biochimiques de la flaveur : production, purification et caractérisation de protéines et enzymes impliquées dans le goût et l’'odorat.

Activités / CV Parcours universitaire (BAC + 3) Licence professionnelle UFR Sciences Exactes et Naturelles REIMS (51).

Programmes de recherche Participe aux programmes ANR FLAMME, ANR PIVERT, ANR NOEMI / ANR MOREAROMA, ANR NEONATOLF

Identifiants externes https://orcid.org/0000-0002-7701-4289 https://scholar.google.fr/citations?user=pDnmuXIAAAAJ&hl=fr&oi=ao https://www.scopus.com/authid/detail.uri?authorId=54943267400 https://www.lens.org/lens/profile/622128163/scholar

Domaines de recherche

Sciences du Vivant [q-bio] Alimentation et Nutrition Biochimie, Biologie Moléculaire Biotechnologies

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Publications

The Ability of Basic and Glycosylated Proline-Rich Proteins to Protect Oral Enzymes from Polyphenol Inhibition

Alena Proskura , Mariam Muradova , Nicolas Poirier , Victoria Ilina , Jeanne Chaloyard et al.
Journal of Agricultural and Food Chemistry, 2025, ⟨10.1021/acs.jafc.5c00821⟩
Article dans une revue hal-05203028 v1
Image document

Inosine-5′-monophosphate interacts with the TAS1R3 subunit to enhance sweet taste detection

Christine Belloir , Lucie Moitrier , Adeline Karolkowski , Nicolas Poirier , F. Neiers et al.
Food Chemistry: Molecular Sciences, 2025, 10, pp.100246. ⟨10.1016/j.fochms.2025.100246⟩
Article dans une revue hal-04958107 v1

Molecular and Cellular Characterization of the Glutathione Transferases Involved in the Olfactory Metabolism of the Mammary Pheromone

Marie-Sabelle Hjeij , Franck Ménétrier , Isabelle Chauvel , Nicolas Poirier , Stéphane Fraichard et al.
Journal of Agricultural and Food Chemistry, 2024, 72 (44), pp.24724-24735. ⟨10.1021/acs.jafc.4c07000⟩
Article dans une revue hal-04761763 v1

Crystallization and Preliminary X-ray Diffraction Study of a Putative β-glycosidase from the Oral Bacteria <i>Prevotella sp.</i>

Mariam Muradova , Nicolas Poirier , Jade Moreno , Alena Proskura , F. Lirussi et al.
Crystallography Reports, 2024, 69 (4), pp.507-512. ⟨10.1134/s1063774523601442⟩
Article dans une revue hal-04737369 v1

<i>Rattus norvegicus</i> Glutathione Transferase Omega 1 Localization in Oral Tissues and Interactions with Food Phytochemicals

Nicolas Poirier , Franck Ménétrier , Jade Moreno , Valentin Boichot , Jean-Marie Heydel et al.
Journal of Agricultural and Food Chemistry, 2024, 72 (11), pp.5887-5897. ⟨10.1021/acs.jafc.4c00483⟩
Article dans une revue hal-04493038 v1
Image document

Microbial β C-S Lyases: Enzymes with Multifaceted Roles in Flavor Generation

Mathieu Schwartz , Nicolas Poirier , Jade Moreno , Alena Proskura , Mélanie Lelièvre et al.
International Journal of Molecular Sciences, 2024, 25 (12), pp.6412. ⟨10.3390/ijms25126412⟩
Article dans une revue (article de synthèse) hal-04642563 v2
Image document

Sweet-inhibiting effects of gurmarin on intake during repeated acute and long-term sugar exposure: A behavioural analysis using an animal model

Raquel Rayo-Morales , Antonio Segura-Carretero , Nicolas Poirier , Loïc Briand , David Garcia-Burgos
Journal of Functional Foods, 2023, 108, pp.105743. ⟨10.1016/j.jff.2023.105743⟩
Article dans une revue hal-04189403 v1
Image document

Comparison of different signal peptides for the efficient secretion of the sweet-tasting plant protein brazzein in Pichia pastoris

Fabrice Neiers , Christine Belloir , Nicolas Poirier , Christian Naumer , Michael Krohn et al.
Life, 2021, 11 (1), pp.46. ⟨10.3390/life11010046⟩
Article dans une revue hal-03144294 v1

The Drosophila odorant-binding protein 28a is involved in the detection of the floral odour ß-ionone

Daniel Gonzalez , Karen Rihani , Fabrice Neiers , Nicolas Poirier , Stéphane Fraichard et al.
Cellular and Molecular Life Sciences, 2020, 77 (13), pp.2565-2577. ⟨10.1007/s00018-019-03300-4⟩
Article dans une revue hal-02384074 v1
Image document

A conserved odorant binding protein is required for essential amino acid detection in Drosophila

Karen Rihani , Stéphane Fraichard , Isabelle Chauvel , Nicolas Poirier , Thomas Delompré et al.
Communications Biology, 2019, 2 (1), pp.425. ⟨10.1038/s42003-019-0673-2⟩
Article dans une revue hal-02384207 v1
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The crystal structure of gurmarin, a sweet taste-suppressing protein: Identification of the amino acid residues essential for inhibition

Maud Sigoillot , Anne Brockoff , Fabrice Neiers , Nicolas Poirier , Christine Belloir et al.
Chemical Senses, 2018, 43 (8), pp.635-643. ⟨10.1093/chemse/bjy054⟩
Article dans une revue hal-02626068 v1

Efficient production and characterization of the sweet-tasting brazzein secreted by the yeast [i]Pichia pastoris[/i]

Nicolas Poirier , Natacha Roudnitzky , Anne Brockhoff , Christine Belloir , Marie Maison et al.
Journal of Agricultural and Food Chemistry, 2012, 60 (39), pp.9807 - 9814. ⟨10.1021/jf301600m⟩
Article dans une revue hal-01223562 v1

Optimization of the production of gurmarin, a sweet-taste-suppressing protein, secreted by the methylotrophic yeast Pichia pastoris.

Maud Sigoillot , Anne Brockhoff , Ewen Lescop , Nicolas Poirier , Wolfgang Meyerhof et al.
Applied Microbiology and Biotechnology, 2012, 96 (5), pp.1253-63. ⟨10.1007/s00253-012-3897-3⟩
Article dans une revue istex hal-00763833 v1
Image document

Understanding the in-mouth release of aroma sulfur compounds from food precursors and the role of microbial C-S lyases

Mathieu Schwartz , Nicolas Poirier , Jade Moreno , Francis Canon , F. Neiers
2. international Meet on food science and technology, Aug 2023, Vancouver, Canada
Communication dans un congrès hal-04464859 v1
Image document

In-mouth metabolism and production of flavor sulfur compounds by oral microbiota enzymes

Mathieu Schwartz , Nicolas Poirier , Karine Gourrat , Francis Canon , F. Neiers
FCT2022 International Conference on Food chemistry and Technology, Oct 2022, Rome, Italy
Communication dans un congrès hal-03986310 v1

Metabolism of flavor sulfur precursors by the oral microbiota

Mathieu Schwartz , Nicolas Poirier , Valentin Boichot , Francis Canon , F. Neiers
Food Science Meeting, May 2022, Valence, Spain
Communication dans un congrès hal-03829017 v1

Metabolism of flavor sulfur precursors by the oral microbiota

Mathieu Schwartz , Nicolas Poirier , Valentin Boichot , Francis Canon , F. Neiers
IATA Conference, Instituto de Agroquímica y Tecnología de Alimentos, Jun 2022, Valence, Spain
Communication dans un congrès hal-03827341 v1

Implication de l’OBP19b dans la perception gustative des acides aminés chez <em>Drosophila melanogaster</em>

Karen Rihani , Stéphane Fraichard , Thomas Delompré , Nicolas Poirier , Isabelle Chauvel et al.
Colloque ARET 2018, May 2018, Dijon, France
Communication dans un congrès hal-02790748 v1

Ligand binding properties of OBP28a, a recombinant odorant binding protein from Drosophila melanogaster

Daniel Gonzalez , Fabrice Neiers , Nicolas Poirier , Guillaume Gotthard , Stéphane Fraichard et al.
18. rencontre du Club de neurobiologie des invertébrés, Jun 2017, Dijon, France. 1 p
Communication dans un congrès hal-01575118 v1

Function of odorant-binding proteins in the Drosophila melanogaster chemoreception

Karen Rihani , Stéphane Fraichard , Nicolas Poirier , Thomas Delompré , Isabelle Chauvel et al.
18. rencontre du Club de neurobiologie des invertébrés, Jun 2017, Dijon, France. 1 p
Communication dans un congrès hal-01575114 v1

The implication of OBP28a in <em>Drosophila melanogaster</em> chemosensory perception

Karen Rihani , Daniel Gonzalez , Fabrice Neiers , Nicolas Poirier , Stéphane Fraichard et al.
31. French Drosophila Meeting (FDM 2017), Nov 2017, Presqu'île de Giens, France
Communication dans un congrès hal-02785694 v1

Function of odorant-binding proteins in the Drosophila melanogaster chemoreception

Karen Rihani , Stéphane Fraichard , Nicolas Poirier , Thomas Delompré , Isabelle Chauvel et al.
23. forum des Jeunes chercheurs, Jun 2017, Dijon, France. 1 p
Communication dans un congrès hal-01575113 v1
Image document

Role of odorant binding protein 28a in <em>Drosophila melanogaster</em> chemosensory perception

Karen Rihani , Daniel Gonzalez , Fabrice Neiers , Nicolas Poirier , Stéphane Fraichard et al.
3. Réunion Annuelle du Groupement de Recherche Odorant-Odeur-Olfaction (GDR O3), Oct 2017, Paris, France
Communication dans un congrès hal-02788727 v1

Purification and characterization of recombinant gurmarin secreted by the yeast Pichia pastoris

Maud M. Sigoillot , Nicolas Poirier , Loïc Briand
20. Congress of the european chemoreception research organisation (ECRO), Sep 2010, Avignon, France. 1 p
Communication dans un congrès hal-02748655 v1

Optimization of the production of recombinant brazzein secreted by the yeast pichia pastoris

Antoine Rachid , Christine Belloir , Joëlle Chevalier , Catherine Desmetz , Marie-Louise Miller et al.
31. annual meeting - Association for chemoreception sciences (AChemS), Apr 2009, Sarasota, Floride, United States. 1 p
Communication dans un congrès hal-02754940 v1

Valoriser les variétés anciennes d'orge brassicole et utiliser les biotechnologies microbiennes pour réduire la teneur en sucre et en alcool des bières tout en préservant l'acceptabilité du consommateur

Hélène Montaz , Olivier Devêvre , Rémi Héliot , Adrien Darphin , Marion Curé et al.
Symposium Harnessing Microbiomes for Sustainable Development (HARMI 2025), Sep 2025, DOLE, France
Poster de conférence hal-05204300 v1

Purification and functional characterization of three human salivary proline-rich proteins involved in astringency

Alena Proskura , Mariam Muradova , Nicolas Poirier , Mathieu Schwartz , Francis Canon et al.
The International Symposium on Olfaction and Taste (ISOT), Jun 2024, Reykjavík, Iceland
Poster de conférence hal-04771592 v1

Role of oral bacterial glycosidases in human flavor perception

Mariam Muradova , Alena Proskura , Nicolas Poirier , Francis Canon , Jean-Marie Heydel et al.
The International Symposium on Olfaction and Taste (ISOT), Jun 2024, Reykjavík, Iceland
Poster de conférence hal-04771642 v1

Rôle du microbiote oral dans la métabolisation de divers précurseurs aromatiques soufrés

Jade Moreno , Mélanie Lelièvre , Nicolas Poirier , Francis Canon , F. Neiers et al.
PIA4 « Excellences » HARMI: HARnessing MIcrobiomes for sustainable development, Sep 2024, Dole, France
Poster de conférence hal-04771730 v1

Characterization of the glutathione transferases involved in the olfactory metabolism of the mammary pheromone

Marie-Sabelle Hjeij , Franck Ménétrier , Isabelle Chauvel , Stéphane Fraichard , Quentin Bonnin et al.
The International Symposium on Olfaction and Taste (ISOT), Jun 2024, Reykjavík, Iceland
Poster de conférence hal-04771537 v1

Strategy for recombinant expression of soluble functional N-terminal domain of human sweet taste receptor produced in Escherichia coli

Christine Belloir , Nicolas Poirier , Lucie Moitrier , Fabrice Neiers , Loïc Briand
41. annual meeting - association for chemoreception sciences (AChemS), Apr 2019, Bonita Springs, Florida, United States. Oxford University Press, Chemical Senses, 44 (7), pp.E71-E71, 2019
Poster de conférence hal-02734758 v1

OBP19b is involved in the taste perception of amino acid in Drosophila melanogaster

Karen Rihani , Stéphane Fraichard , Thomas Delompré , Nicolas Poirier , Isabelle Chauvel et al.
17. European Drosophila Neurobiology Conference (Neurofly 2018), Sep 2018, Cracovie, Poland. , 1 p., 2018
Poster de conférence hal-01857676 v1

The X-ray structure of gurmarin provide new insights into amino acid residues essential for inhibition of the rat sweet taste receptor

Maud M. Sigoillot , Anne Brockoff , Fabrice Neiers , Nicolas Poirier , Christine Belloir et al.
28. Congress of the European Chemoreception Research Organization (ECRO 2018), Sep 2018, Wurtzbourg, Germany. Oxford University Press, Chemical Senses, 44 (3), 1 p., 2019
Poster de conférence hal-02735462 v1

Odorant-binding proteins mutants having novel binding properties

Emilie Barou , Christine Belloir , Nicolas Poirier , Fabrice Neiers , Loïc Briand
26. annual meeting of the european-chemoreception-research-organization (ECRO), Sep 2016, Dijon, France. Oxford University Press, Chemical Senses, 42 (2), 1 p., 2016, Chemical Senses. ⟨10.1093/chemse/bjw120⟩
Poster de conférence hal-01523754 v1

Engineering the sweet-tasting protein brazzein: analysis the effects on stability and sensory profile

Katja Riedel , Fabrice Neiers , Christine Belloir , Isabell Giestler-Al-Madani , Silke Meinecke et al.
The 17. international symposium on Olfaction and taste (ISOT), Jun 2016, Yokohama, Japan. 1 p
Poster de conférence hal-02918213 v1

Purification, biophysical characterization and first crystallization trials of the ligand-binding domain of the human T1R3 sweet taste receptor

Fabrice Neiers , Maud M. Sigoillot , Elodie Maitrepierre , Christine Belloir , Nicolas Poirier et al.
AChemS XXXV-35th Annual Meeting of the Association for Chemoreception Sciences, Apr 2013, Huntington beach, Californie, United States. 1 p., 2013
Poster de conférence hal-02805969 v1

Overexpression of recombinant gurmarin secreted by the yeast Pichia pastoris

Maud M. Sigoillot , Nicolas Poirier , Loïc Briand
AChemS XXXIII-33rd Annual Meeting of the Association for Chemoreception Sciences, Apr 2011, St Pete Beach, Floride, United States. 1 p., 2011
Poster de conférence hal-02807184 v1

P16 - Engineering the full sequence space of the sweet-tasting protein brazzein

Katja Reidel , Fabrice Neiers , Christine Belloir , Isabell Geistler-Al-Madani , Silke Meinecke et al.
/, Chemical Senses, 45 (2), pp.147-147 (P16), 2020, ECRO 2019, ⟨10.1093/chemse/bjaa007⟩
Proceedings/Recueil des communications hal-02885491 v1

Resolution of the X-ray structure of gurmarin: new insights into the molecular mechanism of sweet taste receptor inhibition

Maud Sigoillot , Anne A. Brockhoff , Fabrice Neiers , Nicolas Poirier , Christine Belloir et al.
/, Chemical Senses, 45 (2), pp.124-124, 2020, Abstracts of the 29. annual meeting of the European-Chemoreception-Research-Organization (ECRO)
Proceedings/Recueil des communications hal-02885406 v1