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pascal fender

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Virologie Vectorologie Récepteur Biochimie


Toward the understanding of DSG2 and CD46 interaction with HAdV-11 fiber, a super-complex analysis

Gregory Effantin , Marc-André Hograindleur , Daphna Fenel , Pascal Fender , Emilie Vassal-Stermann
Journal of Virology, 2023, 97 (11), pp.e0091023. ⟨10.1128/jvi.00910-23⟩
Journal articles hal-04426117v1
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Adenovirus-Inspired Virus-like-Particles Displaying Melanoma Tumor Antigen Specifically Target Human DC Subsets and Trigger Antigen-Specific Immune Responses

Solène Besson , David Laurin , Cyrielle Chauvière , Michel Thépaut , Jean-Philippe Kleman
Biomedicines, 2022, 10 (11), pp.2881. ⟨10.3390/biomedicines10112881⟩
Journal articles hal-04027183v1
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The Adenovirus Dodecahedron: Beyond the Platonic Story

Solène Besson , Charles Vragniau , Emilie Vassal-Stermann , Marie Claire Dagher , Pascal Fender
Viruses, 2020, 12 (7), pp.718. ⟨10.3390/v12070718⟩
Journal articles hal-02993412v1
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Binding Mechanism Elucidation of the Acute Respiratory Disease Causing Agent Adenovirus of Serotype 7 to Desmoglein-2

Marc-André Hograindleur , Gregory Effantin , Daphna Fenel , Caroline Mas , André Lieber
Viruses, 2020, 12 (10), pp.1075. ⟨10.3390/v12101075⟩
Journal articles hal-02972725v1
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CryoEM structure of adenovirus type 3 fibre with desmoglein 2 shows an unusual mode of receptor engagement

Emilie Vassal-Stermann , Grégory Effantin , Chloe Zubieta , Wim P Burmeister , Frédéric Iseni
Nature Communications, 2019, 10 (1), pp.1181. ⟨10.1038/s41467-019-09220-y⟩
Journal articles hal-02085944v1

Intermediate-resolution crystal structure of the human adenovirus B serotype 3 fibre knob in complex with the EC2-EC3 fragment of desmoglein 2

Emilie Vassal-Stermann , Stephanie Hutin , Pascal Fender , Wim P Burmeister
Acta crystallographica Section F : Structural biology communications [2014-..], 2019, 75 (12), pp.750-757. ⟨10.1107/S2053230X19015784⟩
Journal articles hal-02413063v1
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Synthetic self-assembling ADDomer platform for highly efficient vaccination by genetically encoded multiepitope display

Charles Vragniau , Joshua Bufton , Frédéric Garzoni , Emilie Stermann , Fruzsina Rabi
Science Advances , 2019, 5 (9), pp.eaaw2853. ⟨10.1126/sciadv.aaw2853⟩
Journal articles hal-02333174v1

Structure-based Design of JOC-x, a Conjugatable Tumor Tight Junction Opener to Enhance Cancer Therapy

Ragan Pitner , Jiho Kim , Jenn Davis-Bergthold , Cheri Turner , Emilie Vassal-Stermann
Scientific Reports, 2019, 9 (1), pp.6169. ⟨10.1038/s41598-019-42229-3⟩
Journal articles hal-02273505v1
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Remodeling of the Actin Network Associated with the Non-Structural Protein 1 (NS1) of West Nile Virus and Formation of NS1-Containing Tunneling Nanotubes

Wilhelm Furnon , Pascal Fender , Marie-Pierre Confort , Sophie Desloire , Sawitree Nangola
Viruses, 2019, 11 (10), pp.901. ⟨10.3390/v11100901⟩
Journal articles hal-02361065v1

Mapping of Adenovirus of serotype 3 fibre interaction to desmoglein 2 revealed a novel ‘non-classical’ mechanism of viral receptor engagement

Emilie Vassal-Stermann , Manon Mottet , Corinne N Ducournau , Frédéric Iseni , Charles Vragniau
Scientific Reports, 2018, 8 (1), pp.8381. ⟨10.1038/s41598-018-26871-x⟩
Journal articles hal-01810699v1

Studies on the Interaction of Tumor-Derived HD5 Alpha Defensins with Adenoviruses and Implications for Oncolytic Adenovirus Therapy.

Charles Vragniau , Jens-Martin Hübner , Peter Beidler , Sucheol Gil , Kamola Saydaminova
Journal of Virology, 2017, 91 (6), pii: e02030-16. ⟨10.1128/JVI.02030-16⟩
Journal articles hal-01497685v1

The Use of Adenovirus Dodecahedron in the Delivery of an Enzymatic Activity in the Cell.

Sudir Sumarheni , Benoit Gallet , Pascal Fender
Biotechnology research international, 2016, 2016, pp.5030589. ⟨10.1155/2016/5030589⟩
Journal articles hal-01341081v1
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New insights into HCV replication in original cells from Aedes mosquitoes

Catherine Fallecker , Alban Caporossi , Yassine Rechoum , Frederic Garzoni , Sylvie Larrat
Virology Journal, 2016, 14 (1), pp.161. ⟨10.1186/s12985-017-0828-z⟩
Journal articles inserm-01577634v1

Intracellular Signaling and Desmoglein 2 Shedding Triggered by Human Adenoviruses Ad3, Ad14, and Ad14P1.

Hongjie Wang , Corinne Ducournau , Kamola Saydaminova , Maximilian Richter , Roma Yumul
Journal of Virology, 2015, 89 (21), pp.10841-59
Journal articles hal-01219724v1

In Vivo Quantification of 5-HT2A Brain Receptors in Mdr1a KO Rats with 123I-R91150 Single-Photon Emission Computed Tomography.

Noé Dumas , Marcelle Moulin-Sallanon , Pascal Fender , Benjamin B Tournier , Nathalie Ginovart
Molecular Imaging, 2015, 14
Journal articles hal-01219727v1

Crystal Structure of the Vaccinia Virus Uracil-DNA Glycosylase in Complex with DNA.

Wim P Burmeister , Nicolas Tarbouriech , Pascal Fender , Céline Contesto-Richefeu , Christophe N Peyrefitte
Journal of Biological Chemistry, 2015, 290 (29), pp.17923-34
Journal articles hal-01219729v1

Preclinical safety and efficacy studies with an affinity-enhanced epithelial junction opener and PEGylated liposomal doxorubicin.

Maximilian Richter , Roma Yumul , Hongjie Wang , Kamola Saydaminova , Martin Ho
Molecular Therapy - Methods and Clinical Development, 2015, 2, pp.15005. ⟨10.1038/mtm.2015.5⟩
Journal articles hal-01162665v1

Human full-length coagulation factor X and a GLA domain-derived 40-mer polypeptide bind to different regions of the adenovirus serotype 5 hexon capsomer.

Sudir Sumarheni , Saw See Hong , Véronique Josserand , Jean-Luc Coll , Pierre Boulanger
Human Gene Therapy, 2014, 25 (4), pp.339-49. ⟨10.1089/hum.2013.222⟩
Journal articles hal-01100391v1

Use of dodecahedron "VLPs" as an alternative to the whole adenovirus.

Pascal Fender
Methods in Molecular Biology, 2014, pp.61-70
Journal articles hal-01100400v1

Structural and functional studies on the interaction of adenovirus fiber knobs and desmoglein 2.

Hongjie Wang , Roma Yumul , Hua Cao , Liang Ran , Xiaolong Fan
Journal of Virology, 2013, 87 (21), pp.11346-62
Journal articles hal-01243502v1

Penton-dodecahedral particles trigger opening of intercellular junctions and facilitate viral spread during adenovirus serotype 3 infection of epithelial cells.

Zhuo-Zhuang Lu , Hongjie Wang , Yiyi Zhang , Hua Cao , Zongyi Li
PLoS Pathogens, 2013, 9 (10), pp.e1003718
Journal articles hal-01243498v1

Impact of human adenovirus type 3 dodecahedron on host cells and its potential role in viral infection.

Pascal Fender , Kathryn Hall , Guy Schoehn , G Eric Blair
Journal of Virology, 2012, 86 (9), pp.5380-5
Journal articles hal-01243638v1

Functional characterisation of the WW minimal domain for delivering therapeutic proteins by adenovirus dodecahedron.

Ana Villegas-Méndez , Pascal Fender , Marina I. Garin , Romy Rothe , Lavinia Liguori
PLoS ONE, 2012, 7 (9), pp.e45416. ⟨10.1371/journal.pone.0045416⟩
Journal articles hal-00821155v1

The structural basis for the integrity of adenovirus Ad3 dodecahedron.

Ewa Szolajska , Wim P Burmeister , Monika Zochowska , Barbara Nerlo , Igor Andreev
PLoS ONE, 2012, 7 (9), pp.e46075. ⟨10.1371/journal.pone.0046075⟩
Journal articles hal-00821152v1
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A fiber-modified adenoviral vector interacts with immunoevasion molecules of the B7 family at the surface of murine leukemia cells derived from dormant tumors.

Elodie Grellier , Katia Lécolle , Sophie Rogée , Cyril Couturier , Jean-Claude d'Halluin
Molecular Cancer, 2011, 10 (1), pp.105. ⟨10.1186/1476-4598-10-105⟩
Journal articles inserm-00626714v1

The adenovirus type 3 dodecahedron's RGD loop comprises an HSPG binding site that influences integrin binding.

Evelyne Gout , Guy Schoehn , Daphna Fenel , Hugues Lortat-Jacob , Pascal Fender
Journal of Biomedicine and Biotechnology, 2010, 2010, pp.541939. ⟨10.1155/2010/541939⟩
Journal articles hal-01063051v1

In vivo delivery of antigens by adenovirus dodecahedron induces cellular and humoral immune responses to elicit antitumor immunity.

Ana Villegas-Mendez , Marina I. Garin , Estela Pineda-Molina , Eugenia Veratti , Juan A. Bueren
Molecular Therapy, 2010, 18 (5), pp.1046-53. ⟨10.1038/mt.2010.16⟩
Journal articles hal-00821159v1

Adenovirus dodecahedron cell attachment and entry are mediated by heparan sulfate and integrins and vary along the cell cycle.

Pascal Fender , Guy Schoehn , Françoise Perron-Sierra , Gordon C Tucker , Hugues Lortat-Jacob
Virology, 2008, 371 (1), pp.155-64. ⟨10.1016/j.virol.2007.09.026⟩
Journal articles hal-00274496v1

Heparan sulphate proteoglycans and viral vectors : ally or foe?

Romain R Vivès , Hugues Lortat-Jacob , Pascal Fender
Current Gene Therapy, 2006, 6 (1), pp.35-44
Journal articles hal-01062653v1

Heparan sulfate proteoglycan mediates the selective attachment and internalization of serotype 3 human adenovirus dodecahedron.

Romain R Vivès , Hugues Lortat-Jacob , Jadwiga Chroboczek , Pascal Fender
Virology, 2004, 321 (2), pp.332-40. ⟨10.1016/j.virol.2004.01.015⟩
Journal articles hal-01061438v1
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Les multiples facettes des adénovirus : Focus à travers les dodécaèdres de l'Ad3 humain

Pascal Fender
Sciences du Vivant [q-bio]. Université de Grenoble, 2006
Habilitation à diriger des recherches tel-01063446v1