PK

Pascale Krejbich Trotot

MCU HDR section 65 du CNU Biologie Santé
48
Documents
Affiliations actuelles
  • Processus Infectieux en Milieu Insulaire Tropical (PIMIT)
  • Université de La Réunion - UFR Santé (UR UFRS)
Contact

Domaines de recherche

Sciences du Vivant [q-bio]

Compétences

interaction Hôte pathogène, mécanismes cellulaires et moléculaires et physiopathologie des arboviroses

Publications

Publications

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A GasPak-Based Ischemia Model for Studying ER Stress–Ischemia Interactions in Human Endothelial Cells

Mathilde Hoareau , Grégorie Lebeau , Luce Muzi , Jérémy Fontaine , Pascale Krejbich-Trotot et al.

Methods and Protocols, 2026, 9 (2), pp.39. ⟨10.3390/mps9020039⟩

Article dans une revue hal-05558009v1
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Exosome-Mediated Antigen Delivery: Unveiling Novel Strategies in Viral Infection Control and Vaccine Design

Daed El Safadi , Alexandre Mokhtari , Morgane Krejbich , Alisé Lagrave , Ugo Hirigoyen et al.

Vaccines, 2024, 12 (3), pp.280. ⟨10.3390/vaccines12030280⟩

Article dans une revue hal-04495903v1

Zika virus restriction of host antioxidant response is mediated by intracellular NS1 and reveals its ability to upregulate Bach1 expression

Grégorie Lebeau , Daed El Safadi , Mathilde Hoarau , Olivier Meilhac , Pascale Krejbich-Trotot et al.

Biochemical and Biophysical Research Communications, 2024, 690, pp.149312. ⟨10.1016/j.bbrc.2023.149312⟩

Article dans une revue hal-04496958v1
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The Antiviral Potential of AdipoRon, an Adiponectin Receptor Agonist, Reveals the Ability of Zika Virus to Deregulate Adiponectin Receptor Expression

Daed El Safadi , Grégorie Lebeau , Jonathan Turpin , Christian Lefebvre D’hellencourt , Nicolas Diotel et al.

Viruses, 2024, 16 (1), pp.24. ⟨10.3390/v16010024⟩

Article dans une revue hal-04496954v1

Cell cycle and mitosis progression during ZIKA virus infection: The viral non-structural protein NS5 as a master regulator of the APC/cyclosome?

Grégorie Lebeau , Mathilde Hoareau , Sébastien Rivière , Daed El Safadi , Christine Robert da Silva et al.

Biochimie, 2024, 221, pp.75-80. ⟨10.1016/j.biochi.2024.01.016⟩

Article dans une revue hal-04496951v1
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The Influence of Metabolism on Immune Response: A Journey to Understand Immunometabolism in the Context of Viral Infection

Daed El Safadi , Aurélie Paulo-Ramos , Mathilde Hoareau , Marjolaine Roche , Pascale Krejbich-Trotot et al.

Viruses, 2023, 15 (12), pp.2399. ⟨10.3390/v15122399⟩

Article dans une revue hal-04496978v1
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Extracellular Vesicles Are Conveyors of the NS1 Toxin during Dengue Virus and Zika Virus Infection

Daed El Safadi , Grégorie Lebeau , Alisé Lagrave , Julien Mélade , Lauriane Grondin et al.

Viruses, 2023, 15 (2), pp.364. ⟨10.3390/v15020364⟩

Article dans une revue hal-04052445v1
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Distribution of Adiponectin Receptors in the Brain of Adult Mouse: Effect of a Single Dose of the Adiponectin Receptor Agonist, AdipoRON, on Ischemic Stroke

Julien Clain , David Couret , Cynthia Planesse , Pascale Krejbich-Trotot , Olivier Meilhac et al.

Brain Sciences, 2022, 12 (5), pp.680. ⟨10.3390/brainsci12050680⟩

Article dans une revue hal-04227844v1
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Apoptosis during ZIKA Virus Infection: Too Soon or Too Late?

Jonathan Turpin , Daed El Safadi , Grégorie Lebeau , Morgane Krejbich , Camille Chatelain et al.

International Journal of Molecular Sciences, 2022, 23 (3), pp.1287. ⟨10.3390/ijms23031287⟩

Article dans une revue hal-03628596v1
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Evidence of RedOX Imbalance during Zika Virus Infection Promoting the Formation of Disulfide-Bond-Dependent Oligomers of the Envelope Protein

Grégorie Lebeau , Jonathan Turpin , Etienne Frumence , Daed El Safadi , Wissal Harrabi et al.

Viruses, 2022, 14 (6), pp.1131. ⟨10.3390/v14061131⟩

Article dans une revue hal-04496984v1
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The Efficient Antiviral Response of A549 Cells Is Enhanced When Mitochondrial Respiration Is Promoted

Grégorie Lebeau , Daed El Safadi , Aurélie Paulo-Ramos , Mathilde Hoareau , Philippe Desprès et al.

Pathogens, 2022, 11 (10), pp.1168. ⟨10.3390/pathogens11101168⟩

Article dans une revue hal-04206718v1
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CHOP Pro-Apoptotic Transcriptional Program in Response to ER Stress Is Hacked by Zika Virus

Jonathan Turpin , Daed El-Safadi , Grégorie Lebeau , Etienne Frumence , Philippe Desprès et al.

International Journal of Molecular Sciences, 2021, 22, pp.3750. ⟨10.3390/ijms22073750⟩

Article dans une revue hal-03702919v1
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Zika E Glycan Loop Region and Guillain–Barré Syndrome-Related Proteins: A Possible Molecular Mimicry to Be Taken in Account for Vaccine Development

Grégorie Lebeau , Etienne Frumence , Jonathan Turpin , Floran Begue , Jean-Jacques Hoarau et al.

Vaccines, 2021, 9 (3), pp.283. ⟨10.3390/vaccines9030283⟩

Article dans une revue hal-04188491v1
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Viral Toxin NS1 Implication in Dengue Pathogenesis Making It a Pivotal Target in Development of Efficient Vaccine

Grégorie Lebeau , Alisé Lagrave , Eva Ogire , Lauriane Grondin , Soundary Seriacaroupin et al.

Vaccines, 2021, 9 (9), ⟨10.3390/vaccines9090946⟩

Article dans une revue hal-03703022v1
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Improvement of immunodetection of the transcription factor C/EBP homologous protein by western blot

Jonathan Turpin , Étienne Frumence , Daed El Safadi , Olivier Meilhac , Pascale Krejbich-Trotot et al.

Analytical Biochemistry, 2020, 601, pp.113775. ⟨10.1016/j.ab.2020.113775⟩

Article dans une revue hal-03120150v1
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Zika virus subversion of chaperone GRP78/BiP expression in A549 cells during UPR activation

Jonathan Turpin , Étienne Frumence , Wissal Harrabi , Juliano Haddad , Chaker El Kalamouni et al.

Biochimie, 2020, 175, pp.99-105. ⟨10.1016/j.biochi.2020.05.011⟩

Article dans une revue hal-03119668v1
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The ZIKA Virus Delays Cell Death Through the Anti-Apoptotic Bcl-2 Family Proteins

Jonathan Turpin , Étienne Frumence , Philippe Desprès , Wildriss Viranaicken , Pascale Krejbich-Trotot

Cells, 2019, Special Issue "Zika Virus and Host Interactions", 8 (11), pp.1338. ⟨10.3390/cells8111338⟩

Article dans une revue hal-02988000v1
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The epidemic of Dengue virus type-2 Cosmopolitan genotype on Reunion Island relates to its active circulation in the Southwestern Indian Ocean neighboring islands

Hervé Pascalis , Jonathan Turpin , Marjolaine Roche , Pascale Krejbich , Gilles Gadea et al.

Heliyon, 2019, 5 (4), pp.e01455. ⟨10.1016/j.heliyon.2019.e01455⟩

Article dans une revue hal-02112801v1
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The Flavonoid Isoquercitrin Precludes Initiation of Zika Virus Infection in Human Cells

Arnaud Gaudry , Sandra Bos , Wildriss Viranaicken , Marjolaine Roche , Pascale Krejbich-Trotot et al.

International Journal of Molecular Sciences, 2018, 19 (4), pii: E1093. ⟨10.3390/ijms19041093⟩

Article dans une revue inserm-01767077v1
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Extract from <i>Aphloia theiformis</i>, an edible indigenous plant from Reunion Island, impairs Zika virus attachment to the host cell surface

Elodie Clain , Laura Sinigaglia , Andrea Cristine Koishi , Olivier Gorgette , Gilles Gadea et al.

Scientific Reports, 2018, 8 (1), pp.10856. ⟨10.1038/s41598-018-29183-2⟩

Article dans une revue hal-02273495v1
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Subversion of the Heme Oxygenase-1 Antiviral Activity by Zika Virus

Chaker El Kalamouni , Étienne Frumence , Sandra Bos , Jonathan Turpin , Brice Nativel et al.

Viruses, 2018, New Advances on Zika Virus Research, 11 (1), ⟨10.3390/v11010002⟩

Article dans une revue hal-02981535v1
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The structural proteins of epidemic and historical strains of Zika virus differ in their ability to initiate viral infection in human host cells

Sandra Bos , Wildriss Viranaicken , Jonathan Turpin , Chaker El Kalamouni , Marjolaine Roche et al.

Virology, 2018, 516, pp.265 - 273. ⟨10.1016/j.virol.2017.12.003⟩

Article dans une revue hal-01702657v1

ClearColi BL21(DE3)-based expression of Zika virus antigens illustrates a rapid method of antibody production against emerging pathogens

Wildriss Viranaicken , Brice Nativel , Pascale Krejbich-Trotot , Wissal Harrabi , Sandra Bos et al.

Biochimie, 2017, 142 (9), pp.179 - 182. ⟨10.1016/j.biochi.2017.09.011⟩

Article dans une revue hal-01689690v1
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Recombinant Zika NS1 protein secreted from Vero cells is efficient for inducing production of immune serum against NS1 dimer

Wildriss Viranaicken , Alexia Ndebo , Sandra Bos , Philippe Souque , Gilles Gadea et al.

International Journal of Molecular Sciences, 2017, 19 (1), pp.38. ⟨10.3390/ijms19010038⟩

Article dans une revue hal-01703097v1

The South Pacific epidemic strain of Zika virus replicates efficiently in human epithelial A549 cells leading to IFN-β production and apoptosis induction

Étienne Frumence , Marjolaine Roche , Pascale Krejbich-Trotot , Chaker El Kalamouni , Brice Nativel et al.

Virology, 2016, 493, pp.217-226. ⟨10.1016/j.virol.2016.03.006⟩

Article dans une revue hal-01980899v1
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The growth of arthralgic Ross River virus is restricted in human monocytic cells

Pascale Krejbich-Trotot , Essia Belarbi , Miora Ralambondrainy , Chaker El Kalamouni , Wildriss Viranaicken et al.

Virus Research, 2016, 225, pp.64-68. ⟨10.1016/j.virusres.2016.09.007⟩

Article dans une revue inserm-01375991v2
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Mutation in a primate-conserved retrotransposon reveals a noncoding RNA as a mediator of infantile encephalopathy

François Cartault , Patrick Munier , Edgar Benko , Isabelle Desguerre , Sylvain Hanein et al.

Proceedings of the National Academy of Sciences of the United States of America, 2012, 109 (13), pp.4980-4985. ⟨10.1073/pnas.1111596109⟩

Article dans une revue hal-01285444v1

Chikungunya virus mobilizes the apoptotic machinery to invade host cell defenses

Pascale Krejbich-Trotot , Melanie Denizot , Jean-Jacques Hoarau , Marie-Christine Jaffar-Bandjee , Trina Das et al.

FASEB Journal, 2011, 25 (1), pp.314--325. ⟨10.1096/fj.10-164178⟩

Article dans une revue hal-01274616v1
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Chikungunya triggers an autophagic process which promotes viral replication.

Pascale Krejbich-Trotot , Bernard Gay , Ghislaine Li-Pat-Yuen , Jean-Jacques Hoarau , Marie-Christine Jaffar-Bandjee et al.

Virology Journal, 2011, 8 (1), pp.432. ⟨10.1186/1743-422X-8-432⟩

Article dans une revue hal-00623020v1

Activation and Control of CNS Innate Immune Responses in Health and Diseases: A Balancing Act Finely Tuned by Neuroimmune Regulators (NIReg)

Jean-Jacques Hoarau , Pascale Krejbich-Trotot , Marie-Christine Jaffar-Bandjee , Trina Das , Gerard-Vincent Thon-Hon et al.

Current Drug Targets -CNS and Neurological Disorders-, 2011, 10 (1), pp.25--43. ⟨10.2174/187152711794488601⟩

Article dans une revue hal-01274615v1

Chikungunya fever: CNS infection and pathologies of a re-emerging arbovirus

Trina Das , Marie-Christine Jaffar-Bandjee , Jean-Jacques Hoarau , Pascale Krejbich-Trotot , Melanie Denizot et al.

Progress in Neurobiology, 2010, Neglected Infectious Diseases of the Nervous System: Pathogenesis and Global Impact, 91 (2), pp.121--129. ⟨10.1016/j.pneurobio.2009.12.006⟩

Article dans une revue istex hal-01274626v1

Emergence and clinical insights into the pathology of Chikungunya virus infection

Marie-Christine Jaffar-Bandjee , Duksha Ramful , Bernard-Alex Gaüzere , Jean-Jacques Hoarau , Pascale Krejbich-Trotot et al.

Expert Review of Anti-infective Therapy, 2010, 8 (9), pp.987--996. ⟨10.1586/eri.10.92⟩

Article dans une revue hal-01274634v1

Persistent Chronic Inflammation and Infection by Chikungunya Arthritogenic Alphavirus in Spite of a Robust Host Immune Response

Jean-Jacques Hoarau , Marie-Christine Jaffar-Bandjee , Pascale Krejbich-Trotot , Trina Das , Ghislaine Li-Pat-Yuen et al.

Journal of Immunology, 2010, 184 (10), pp.5914--5927. ⟨10.4049/jimmunol.0900255⟩

Article dans une revue hal-01285461v1

Chikungunya virus takes centre stage in virally induced arthritis: possible cellular and molecular mechanisms to pathogenesis

Marie-Christine Jaffar-Bandjee , Trina Das , Jean-Jacques Hoarau , Pascale Krejbich-Trotot , Mélanie Denizot et al.

Microbes and Infection, 2009, Forum on Chikungunya, 11 (14–15), pp.1206--1218. ⟨10.1016/j.micinf.2009.10.001⟩

Article dans une revue istex hal-01274636v1

The superoxide dismutase inhibitor diethyldithiocarbamate has antagonistic effects on apoptosis by triggering both cytochrome c release and caspase inhibition

Anne Dumay , Vincent Rincheval , Pascale Trotot , Bernard Mignotte , Jean-Luc Vayssière

Free Radical Biology and Medicine, 2006, 40 (8), pp.1377-1390. ⟨10.1016/j.freeradbiomed.2005.12.005⟩

Article dans une revue istex hal-04497237v1

Caspase-9 can antagonize p53-induced apoptosis by generating a p76Rb truncated form of Rb

Christophe Lemaire , Nelly Godefroy , Ioana Costina-Parvu , Vincent Rincheval , Flore Renaud et al.

Oncogene, 2005, 24 (20), pp.3297-3308. ⟨10.1038/sj.onc.1208493⟩

Article dans une revue hal-04497207v1
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Bcl-2 can promote p53-dependent senescence versus apoptosis without affecting the G1/S transition

Vincent Rincheval , Flore Renaud , Christophe Lemaire , Nelly Godefroy , Pascale Trotot et al.

Biochemical and Biophysical Research Communications, 2002, 298 (2), pp.282-288. ⟨10.1016/S0006-291X(02)02454-3⟩

Article dans une revue hal-03002751v1
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Aeromonas hydrophila Adenylyl Cyclase 2: a New Class of Adenylyl Cyclases with Thermophilic Properties and Sequence Similarities to Proteins from Hyperthermophilic Archaebacteria

Odile Sismeiro , Pascale Trotot , Francis Biville , Christian Vivares , Antoine Danchin

Journal of Bacteriology, 1998, 180 (13), pp.3339-3344. ⟨10.1128/JB.180.13.3339-3344.1998⟩

Article dans une revue hal-04497201v1

Comparative analysis of the cya locus in enterobacteria and related Gram-negative facultative anaerobes

P. Trotot , O. Sismeiro , C. Vivarès , P. Glaser , A. Bresson-Roy et al.

Biochimie, 1996, 78 (4), pp.277-287. ⟨10.1016/0300-9084(96)82192-4⟩

Article dans une revue istex hal-04497009v1

Transcriptional Activity in 3T3, F9, and PCC4 Embryonal Carcinoma Cells: A Systematic Deletion and Linker-Scanning Study of the Polyomavirus Enhancer

Pascale Trotot , Francisca Mechali , Daniel Blangy , Michel Lacasa

Virology, 1994, 202 (2), pp.724-734. ⟨10.1006/viro.1994.1394⟩

Article dans une revue istex hal-04497003v1

Dipeptidyl peptidase IV (CD 26) gene expression in enterocyte-like colon cancer cell lines HT-29 and Caco-2. Cloning of the complete human coding sequence and changes of dipeptidyl peptidase IV mRNA levels during cell differentiation.

D. Darmoul , M. Lacasa , L. Baricault , D. Marguet , Sapin Christian et al.

Journal of Biological Chemistry, 1992, 267 ((7)), pp.4824-33

Article dans une revue hal-00815247v1