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Pascale Krejbich Trotot

MCU HDR section 65 du CNU Biologie Santé
Current affiliations
  • 418783
  • 521260
Researcher identifiers
  • IdHAL pascale-krejbich-trotot
  • ORCID 0000-0001-7329-1716
  • Google Scholar :

Research domains

Life Sciences [q-bio]


interaction Hôte pathogène, mécanismes cellulaires et moléculaires et physiopathologie des arboviroses


Zika virus restriction of host antioxidant response is mediated by intracellular NS1 and reveals its ability to upregulate Bach1 expression

Grégorie Lebeau , Daed El Safadi , Mathilde Hoarau , Olivier Meilhac , Pascale Krejbich-Trotot
Biochemical and Biophysical Research Communications, 2024, 690, pp.149312. ⟨10.1016/j.bbrc.2023.149312⟩
Journal articles hal-04496958v1
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Exosome-Mediated Antigen Delivery: Unveiling Novel Strategies in Viral Infection Control and Vaccine Design

Daed El Safadi , Alexandre Mokhtari , Morgane Krejbich , Alisé Lagrave , Ugo Hirigoyen
Vaccines, 2024, 12 (3), pp.280. ⟨10.3390/vaccines12030280⟩
Journal articles hal-04495903v1
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The Antiviral Potential of AdipoRon, an Adiponectin Receptor Agonist, Reveals the Ability of Zika Virus to Deregulate Adiponectin Receptor Expression

Daed El Safadi , Grégorie Lebeau , Jonathan Turpin , Christian Lefebvre D’hellencourt , Nicolas Diotel
Viruses, 2024, 16 (1), pp.24. ⟨10.3390/v16010024⟩
Journal articles hal-04496954v1

Cell cycle and mitosis progression during ZIKA virus infection: The viral non-structural protein NS5 as a master regulator of the APC/cyclosome?

Grégorie Lebeau , Mathilde Hoareau , Sébastien Rivière , Daed El Safadi , Christine Robert da Silva
Biochimie, 2024, 221, pp.75-80. ⟨10.1016/j.biochi.2024.01.016⟩
Journal articles hal-04496951v1
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The Influence of Metabolism on Immune Response: A Journey to Understand Immunometabolism in the Context of Viral Infection

Daed El Safadi , Aurélie Paulo-Ramos , Mathilde Hoareau , Marjolaine Roche , Pascale Krejbich-Trotot
Viruses, 2023, 15 (12), pp.2399. ⟨10.3390/v15122399⟩
Journal articles hal-04496978v1
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Extracellular Vesicles Are Conveyors of the NS1 Toxin during Dengue Virus and Zika Virus Infection

Daed El Safadi , Grégorie Lebeau , Alisé Lagrave , Julien Mélade , Lauriane Grondin
Viruses, 2023, 15 (2), pp.364. ⟨10.3390/v15020364⟩
Journal articles hal-04052445v1
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Evidence of RedOX Imbalance during Zika Virus Infection Promoting the Formation of Disulfide-Bond-Dependent Oligomers of the Envelope Protein

Grégorie Lebeau , Jonathan Turpin , Etienne Frumence , Daed El Safadi , Wissal Harrabi
Viruses, 2022, 14 (6), pp.1131. ⟨10.3390/v14061131⟩
Journal articles hal-04496984v1
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Apoptosis during ZIKA Virus Infection: Too Soon or Too Late?

Jonathan Turpin , Daed El Safadi , Grégorie Lebeau , Morgane Krejbich , Camille Chatelain
International Journal of Molecular Sciences, 2022, 23 (3), pp.1287. ⟨10.3390/ijms23031287⟩
Journal articles hal-03628596v1
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The Efficient Antiviral Response of A549 Cells Is Enhanced When Mitochondrial Respiration Is Promoted

Grégorie Lebeau , Daed El Safadi , Aurélie Paulo-Ramos , Mathilde Hoareau , Philippe Desprès
Pathogens, 2022, 11 (10), pp.1168. ⟨10.3390/pathogens11101168⟩
Journal articles hal-04206718v1
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Distribution of Adiponectin Receptors in the Brain of Adult Mouse: Effect of a Single Dose of the Adiponectin Receptor Agonist, AdipoRON, on Ischemic Stroke

Julien Clain , David Couret , Cynthia Planesse , Pascale Krejbich-Trotot , Olivier Meilhac
Brain Sciences, 2022, 12 (5), pp.680. ⟨10.3390/brainsci12050680⟩
Journal articles hal-04227844v1
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Zika E Glycan Loop Region and Guillain–Barré Syndrome-Related Proteins: A Possible Molecular Mimicry to Be Taken in Account for Vaccine Development

Grégorie Lebeau , Etienne Frumence , Jonathan Turpin , Floran Begue , Jean-Jacques Hoarau
Vaccines, 2021, 9 (3), pp.283. ⟨10.3390/vaccines9030283⟩
Journal articles hal-04188491v1
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Viral Toxin NS1 Implication in Dengue Pathogenesis Making It a Pivotal Target in Development of Efficient Vaccine

Grégorie Lebeau , Alisé Lagrave , Eva Ogire , Lauriane Grondin , Soundary Seriacaroupin
Vaccines, 2021, 9 (9), ⟨10.3390/vaccines9090946⟩
Journal articles hal-03703022v1
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CHOP Pro-Apoptotic Transcriptional Program in Response to ER Stress Is Hacked by Zika Virus

Jonathan Turpin , Daed El-Safadi , Grégorie Lebeau , Etienne Frumence , Philippe Desprès
International Journal of Molecular Sciences, 2021, 22, pp.3750. ⟨10.3390/ijms22073750⟩
Journal articles hal-03702919v1
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Improvement of immunodetection of the transcription factor C/EBP homologous protein by western blot

Jonathan Turpin , Étienne Frumence , Daed El Safadi , Olivier Meilhac , Pascale Krejbich-Trotot
Analytical Biochemistry, 2020, 601, pp.113775. ⟨10.1016/j.ab.2020.113775⟩
Journal articles hal-03120150v1
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Zika virus subversion of chaperone GRP78/BiP expression in A549 cells during UPR activation

Jonathan Turpin , Étienne Frumence , Wissal Harrabi , Juliano Haddad , Chaker El Kalamouni
Biochimie, 2020, 175, pp.99-105. ⟨10.1016/j.biochi.2020.05.011⟩
Journal articles hal-03119668v1
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The epidemic of Dengue virus type-2 Cosmopolitan genotype on Reunion Island relates to its active circulation in the Southwestern Indian Ocean neighboring islands

Hervé Pascalis , Jonathan Turpin , Marjolaine Roche , Pascale Krejbich , Gilles Gadea
Heliyon, 2019, 5 (4), pp.e01455. ⟨10.1016/j.heliyon.2019.e01455⟩
Journal articles hal-02112801v1
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The ZIKA Virus Delays Cell Death Through the Anti-Apoptotic Bcl-2 Family Proteins

Jonathan Turpin , Étienne Frumence , Philippe Desprès , Wildriss Viranaicken , Pascale Krejbich-Trotot
Cells, 2019, Special Issue "Zika Virus and Host Interactions", 8 (11), pp.1338. ⟨10.3390/cells8111338⟩
Journal articles hal-02988000v1
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Extract from Aphloia theiformis, an edible indigenous plant from Reunion Island, impairs Zika virus attachment to the host cell surface

Elodie Clain , Laura Sinigaglia , Andrea Cristine Koishi , Olivier Gorgette , Gilles Gadea
Scientific Reports, 2018, 8 (1), pp.10856. ⟨10.1038/s41598-018-29183-2⟩
Journal articles hal-02273495v1
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Subversion of the Heme Oxygenase-1 Antiviral Activity by Zika Virus

Chaker El Kalamouni , Étienne Frumence , Sandra Bos , Jonathan Turpin , Brice Nativel
Viruses, 2018, New Advances on Zika Virus Research, 11 (1), ⟨10.3390/v11010002⟩
Journal articles hal-02981535v1
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The structural proteins of epidemic and historical strains of Zika virus differ in their ability to initiate viral infection in human host cells

Sandra Bos , Wildriss Viranaicken , Jonathan Turpin , Chaker El Kalamouni , Marjolaine Roche
Virology, 2018, 516, pp.265 - 273. ⟨10.1016/j.virol.2017.12.003⟩
Journal articles hal-01702657v1
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The Flavonoid Isoquercitrin Precludes Initiation of Zika Virus Infection in Human Cells

Arnaud Gaudry , Sandra Bos , Wildriss Viranaicken , Marjolaine Roche , Pascale Krejbich-Trotot
International Journal of Molecular Sciences, 2018, 19 (4), pii: E1093. ⟨10.3390/ijms19041093⟩
Journal articles inserm-01767077v1

ClearColi BL21(DE3)-based expression of Zika virus antigens illustrates a rapid method of antibody production against emerging pathogens

Wildriss Viranaicken , Brice Nativel , Pascale Krejbich-Trotot , Wissal Harrabi , Sandra Bos
Biochimie, 2017, 142 (9), pp.179 - 182. ⟨10.1016/j.biochi.2017.09.011⟩
Journal articles hal-01689690v1
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Recombinant Zika NS1 protein secreted from Vero cells is efficient for inducing production of immune serum against NS1 dimer

Wildriss Viranaicken , Alexia Ndebo , Sandra Bos , Philippe Souque , Gilles Gadea
International Journal of Molecular Sciences, 2017, 19 (1), pp.38. ⟨10.3390/ijms19010038⟩
Journal articles hal-01703097v1
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The growth of arthralgic Ross River virus is restricted in human monocytic cells

Pascale Krejbich-Trotot , Essia Belarbi , Miora Ralambondrainy , Chaker El Kalamouni , Wildriss Viranaicken
Virus Research, 2016, 225, pp.64-68. ⟨10.1016/j.virusres.2016.09.007⟩
Journal articles inserm-01375991v2

The South Pacific epidemic strain of Zika virus replicates efficiently in human epithelial A549 cells leading to IFN-β production and apoptosis induction

Étienne Frumence , Marjolaine Roche , Pascale Krejbich-Trotot , Chaker El Kalamouni , Brice Nativel
Virology, 2016, 493, pp.217-226. ⟨10.1016/j.virol.2016.03.006⟩
Journal articles hal-01980899v1
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Mutation in a primate-conserved retrotransposon reveals a noncoding RNA as a mediator of infantile encephalopathy

François Cartault , Patrick Munier , Edgar Benko , Isabelle Desguerre , Sylvain Hanein
Proceedings of the National Academy of Sciences of the United States of America, 2012, 109 (13), pp.4980-4985. ⟨10.1073/pnas.1111596109⟩
Journal articles hal-01285444v1

Activation and Control of CNS Innate Immune Responses in Health and Diseases: A Balancing Act Finely Tuned by Neuroimmune Regulators (NIReg)

Jean-Jacques Hoarau , Pascale Krejbich-Trotot , Marie-Christine Jaffar-Bandjee , Trina Das , Gerard-Vincent Thon-Hon
Current Drug Targets -CNS and Neurological Disorders-, 2011, 10 (1), pp.25--43. ⟨10.2174/187152711794488601⟩
Journal articles hal-01274615v1
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Chikungunya triggers an autophagic process which promotes viral replication.

Pascale Krejbich-Trotot , Bernard Gay , Ghislaine Li-Pat-Yuen , Jean-Jacques Hoarau , Marie-Christine Jaffar-Bandjee
Virology Journal, 2011, 8 (1), pp.432. ⟨10.1186/1743-422X-8-432⟩
Journal articles hal-00623020v1

Chikungunya virus mobilizes the apoptotic machinery to invade host cell defenses

Pascale Krejbich-Trotot , Melanie Denizot , Jean-Jacques Hoarau , Marie-Christine Jaffar-Bandjee , Trina Das
FASEB Journal, 2011, 25 (1), pp.314--325. ⟨10.1096/fj.10-164178⟩
Journal articles hal-01274616v1

Persistent Chronic Inflammation and Infection by Chikungunya Arthritogenic Alphavirus in Spite of a Robust Host Immune Response

Jean-Jacques Hoarau , Marie-Christine Jaffar-Bandjee , Pascale Krejbich-Trotot , Trina Das , Ghislaine Li-Pat-Yuen
Journal of Immunology, 2010, 184 (10), pp.5914--5927. ⟨10.4049/jimmunol.0900255⟩
Journal articles hal-01285461v1

Chikungunya fever: CNS infection and pathologies of a re-emerging arbovirus

Trina Das , Marie-Christine Jaffar-Bandjee , Jean-Jacques Hoarau , Pascale Krejbich-Trotot , Melanie Denizot
Progress in Neurobiology, 2010, Neglected Infectious Diseases of the Nervous System: Pathogenesis and Global Impact, 91 (2), pp.121--129. ⟨10.1016/j.pneurobio.2009.12.006⟩
Journal articles hal-01274626v1

Emergence and clinical insights into the pathology of Chikungunya virus infection

Marie-Christine Jaffar-Bandjee , Duksha Ramful , Bernard-Alex Gaüzere , Jean-Jacques Hoarau , Pascale Krejbich-Trotot
Expert Review of Anti-infective Therapy, 2010, 8 (9), pp.987--996. ⟨10.1586/eri.10.92⟩
Journal articles hal-01274634v1

Chikungunya virus takes centre stage in virally induced arthritis: possible cellular and molecular mechanisms to pathogenesis

Marie-Christine Jaffar-Bandjee , Trina Das , Jean-Jacques Hoarau , Pascale Krejbich-Trotot , Mélanie Denizot
Microbes and Infection, 2009, Forum on Chikungunya, 11 (14–15), pp.1206--1218. ⟨10.1016/j.micinf.2009.10.001⟩
Journal articles hal-01274636v1

The superoxide dismutase inhibitor diethyldithiocarbamate has antagonistic effects on apoptosis by triggering both cytochrome c release and caspase inhibition

Anne Dumay , Vincent Rincheval , Pascale Trotot , Bernard Mignotte , Jean-Luc Vayssière
Free Radical Biology and Medicine, 2006, 40 (8), pp.1377-1390. ⟨10.1016/j.freeradbiomed.2005.12.005⟩
Journal articles hal-04497237v1

Caspase-9 can antagonize p53-induced apoptosis by generating a p76Rb truncated form of Rb

Christophe Lemaire , Nelly Godefroy , Ioana Costina-Parvu , Vincent Rincheval , Flore Renaud
Oncogene, 2005, 24 (20), pp.3297-3308. ⟨10.1038/sj.onc.1208493⟩
Journal articles hal-04497207v1
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Bcl-2 can promote p53-dependent senescence versus apoptosis without affecting the G1/S transition

Vincent Rincheval , Flore Renaud , Christophe Lemaire , Nelly Godefroy , Pascale Trotot
Biochemical and Biophysical Research Communications, 2002, 298 (2), pp.282-288. ⟨10.1016/S0006-291X(02)02454-3⟩
Journal articles hal-03002751v1
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Aeromonas hydrophila Adenylyl Cyclase 2: a New Class of Adenylyl Cyclases with Thermophilic Properties and Sequence Similarities to Proteins from Hyperthermophilic Archaebacteria

Odile Sismeiro , Pascale Trotot , Francis Biville , Christian Vivares , Antoine Danchin
Journal of Bacteriology, 1998, 180 (13), pp.3339-3344. ⟨10.1128/JB.180.13.3339-3344.1998⟩
Journal articles hal-04497201v1

Comparative analysis of the cya locus in enterobacteria and related Gram-negative facultative anaerobes

P. Trotot , O. Sismeiro , C. Vivarès , P. Glaser , A. Bresson-Roy
Biochimie, 1996, 78 (4), pp.277-287. ⟨10.1016/0300-9084(96)82192-4⟩
Journal articles hal-04497009v1

Transcriptional Activity in 3T3, F9, and PCC4 Embryonal Carcinoma Cells: A Systematic Deletion and Linker-Scanning Study of the Polyomavirus Enhancer

Pascale Trotot , Francisca Mechali , Daniel Blangy , Michel Lacasa
Virology, 1994, 202 (2), pp.724-734. ⟨10.1006/viro.1994.1394⟩
Journal articles hal-04497003v1

Dipeptidyl peptidase IV (CD 26) gene expression in enterocyte-like colon cancer cell lines HT-29 and Caco-2. Cloning of the complete human coding sequence and changes of dipeptidyl peptidase IV mRNA levels during cell differentiation.

D. Darmoul , M. Lacasa , L. Baricault , D. Marguet , Sapin Christian
Journal of Biological Chemistry, 1992, 267 ((7)), pp.4824-33
Journal articles hal-00815247v1