PW

Pascale Winckler

Research engineer at Institut Agro Dijon
56
Documents
Affiliations actuelles
  • Institut Agro Dijon
  • Procédés Alimentaires et Microbiologiques [Dijon] (PAM)
  • Procédés Microbiologiques et Biotechnologiques (PMB)
  • Dispositif Inter-régional d'Imagerie Cellulaire [Dijon] (DImaCell)

Présentation

Domaines de recherche

Physique [physics] Sciences du Vivant [q-bio]

Compétences

Fluorescence microscopy Vibrationnal spectroscopy OPTIR

Publications

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Publications

Optical photothermal infrared (OPTIR) spectroscopy assisted by machine learning for lactic acid bacteria identification at strain level

Paul Lagneaux , Nathan Widjaja , Bastien Lagneaux , Thi Kim Chi Nguyen , Hélène Licandro et al.

Analyst, In press, ⟨10.1039/D5AN01093D⟩

Article dans une revue hal-05478813v1
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The nuclear dynamic of CDC48 is affected during the immune response in plants

Damien Inès , Aymeric Leray , Pascale Winckler , Pierre-Emmanuel Courty , David Wendehenne et al.

Plant Signaling and Behavior, 2025, 20 (1), pp.2488104. ⟨10.1080/15592324.2025.2488104⟩

Article dans une revue hal-05023684v1
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Influence of hydration on calcium dipicolinate (CaDPA) during UVb and UVc exposure studied via Raman, FTIR and O-PTIR spectroscopy

Jonathan Dikec , Maxime Pacheco , Laurence Dujourdy , Christophe Sandt , Pascale Winckler et al.

Journal of Photochemistry and Photobiology A: Chemistry, 2023, 443, pp.114823. ⟨10.1016/j.jphotochem.2023.114823⟩

Article dans une revue hal-04098103v1
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The grapevine LysM receptor-like kinase VvLYK5-1 recognizes chitin oligomers through its association with VvLYK1-1

Thibault Roudaire , Tania Marzari , David Landry , Birgit Löffelhardt , Andrea A Gust et al.

Frontiers in Plant Science, 2023, 14, ⟨10.3389/fpls.2023.1130782⟩

Article dans une revue hal-03976584v1
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Membrane protective role of autophagic machinery during infection of epithelial cells by Candida albicans

Pierre Lapaquette , Amandine Ducreux , Louise Basmaciyan , Tracy Paradis , Fabienne Bon et al.

Gut microbes, 2022, 14 (1), pp.2004798. ⟨10.1080/19490976.2021.2004798⟩

Article dans une revue hal-03553809v1
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Multispectral fluorescence sensitivity to acidic and polyphenolic changes in Chardonnay wines – The case study of malolactic fermentation

Maxime Pacheco , Pascale Winckler , Ambroise Marin , Jean-Marie Perrier-Cornet , Christian Coelho

Food Chemistry, 2022, 370, pp.131370. ⟨10.1016/j.foodchem.2021.131370⟩

Article dans une revue hal-03430039v1

New insights into moisture sorption characteristics, nutritional composition, and antioxidant and morphological properties of dried duckweed [ Wolffia arrhiza (L.) Wimm]

Supuksorn Masavang , Pascale Winckler , Arak Tira‐umphon , Traiphop Phahom

Journal of the Science of Food and Agriculture, 2022, 102 (5), pp.2135-2143. ⟨10.1002/jsfa.11555⟩

Article dans une revue hal-03394345v1

Uptake of UVc induced photoproducts of dipicolinic acid by Bacillus subtilis spores – Effects on the germination and UVc resistance of the spores

Jonathan Dikec , Maxime Pacheco , M. Lavaud , Pascale Winckler , Jean-Marie Perrier-Cornet

Journal of Photochemistry and Photobiology B: Biology, 2022, 236, pp.112569. ⟨10.1016/j.jphotobiol.2022.112569⟩

Article dans une revue hal-03792017v1
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Spectroscopic and microscopic characterization of dipicolinic acid and its salt photoproducts – A UVc effect study on DPA in solution and in bacterial spores

Maxime Pacheco , Jonathan Dikec , Pascale Winckler , Jean-Marie Perrier-Cornet , Christian Coelho

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy [1994-..], 2022, 280, pp.121502. ⟨10.1016/j.saa.2022.121502⟩

Article dans une revue hal-03761812v1

Effects of pulsed near infrared light (NIR) on Bacillus subtilis spores

Jonathan Dikec , Shaliha Bechoua , Pascale Winckler , Jean-Marie Perrier-Cornet

Journal of Photochemistry and Photobiology B: Biology, 2022, 234, pp.112530. ⟨10.1016/j.jphotobiol.2022.112530⟩

Article dans une revue hal-03762800v1

The chaperone‐like protein Cdc48 regulates ubiquitin‐proteasome system in plants

Claire Rosnoblet , Pauline Chatelain , Agnès Klinguer , Hervé Bègue , Pascale Winckler et al.

Plant, Cell and Environment, 2021, 44 (8), pp.2636-2655. ⟨10.1111/pce.14073⟩

Article dans une revue hal-03216083v1

Shedding Light on the Formation and Structure of Kombucha Biofilm Using Two-Photon Fluorescence Microscopy

Thierry Tran , Cosette Grandvalet , Pascale Winckler , François Verdier , Antoine Martin et al.

Frontiers in Microbiology, 2021, 12, pp.725379. ⟨10.3389/fmicb.2021.725379⟩

Article dans une revue hal-03338898v1

The chaperone-like protein CDC48 regulates ascorbate peroxidase in tobacco

Hervé Begue , Angelique Besson-Bard , Cécile Blanchard , Pascale Winckler , Stéphane Bourque et al.

Journal of Experimental Botany, 2019, 70 (10), pp.2665-2681. ⟨10.1093/jxb/erz097⟩

Article dans une revue hal-02292582v1

Analysis of multivariate images in fluorescence microscopy

Caroline Peltier , Pascale Winckler , Laurence Dujourdy , Shaliha Bechoua , Jean-Marie Perrier-Cornet

Methods and Applications in Fluorescence, 2019, 7 (3), pp.035004. ⟨10.1088/2050-6120/ab1886⟩

Article dans une revue hal-02173638v1
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Four hundred years of cork imaging: New advances in the characterization of the cork structure

Kevin Crouvisier-Urion , Julie Chanut , Aurélie Lagorce , Pascale Winckler , Zi Wang et al.

Scientific Reports, 2019, 9 (1), pp.19682. ⟨10.1038/s41598-019-55193-9⟩

Article dans une revue hal-02430216v1
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Resveratrol-Induced Xenophagy Promotes Intracellular Bacteria Clearance in Intestinal Epithelial Cells and Macrophages

Jana Al Azzaz , Aurélie Rieu , Virginie Aires , Dominique Delmas , Johanna Chluba et al.

Frontiers in Immunology, 2019, 9, pp.3149. ⟨10.3389/fimmu.2018.03149⟩

Article dans une revue hal-02014598v1

Effect of high hydrostatic pressure on extraction of B-phycoerythrin from Porphyridium cruentum: Use of confocal microscopy and image processing

Thierry Tran , Emmanuel Denimal , Céline Lafarge , Ludovic Journaux , John Aldo Lee et al.

Algal Research - Biomass, Biofuels and Bioproducts, 2019, 38 (UNSP 101394), pp.1-8. ⟨10.1016/j.algal.2018.101394⟩

Article dans une revue hal-02173597v1
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Ex situ and in situ investigation of protein/exopolysaccharide complex in Porphyridium cruentum biomass resuspension

Thierry Tran , Céline Lafarge , Pascale Winckler , Rémi Pradelles , Nathalie Cayot et al.

Algal Research - Biomass, Biofuels and Bioproducts, 2019, 41, pp.101544. ⟨10.1016/j.algal.2019.101544⟩

Article dans une revue hal-02173261v1
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Time-resolved Fluorescence and Generalized Polarization: Innovative tools to assess bull sperm membrane dynamics during slow freezing

Shaliha Bechoua , Pascale Winckler , Audrey Jossier , Caroline Peltier , Frédéric Delize et al.

Cryobiology, 2019, 91, pp.69-76. ⟨10.1016/j.cryobiol.2019.10.196⟩

Article dans une revue hal-02354329v1
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Cell Death Mechanisms Induced by Photo-Oxidation Studied at the Cell Scale in the Yeast Saccharomyces cerevisiae

Cédric Grangeteau , Florine Lepinois , Pascale Winckler , Jean-Marie Perrier-Cornet , Sébastien Dupont et al.

Frontiers in Microbiology, 2018, 9, ⟨10.3389/fmicb.2018.02640⟩

Article dans une revue hal-01950369v1

Fluorescence lifetime and UV-Vis spectroscopy to evaluate the interactions between quercetin and its yeast microcapsule

Bao-Ngoc Pham-Hoang , Pascale Winckler , Yves Waché

Biotechnology Journal, 2018, 13 (1), ⟨10.1002/biot.201700389⟩

Article dans une revue hal-01620011v1

Interaction between Cork and Yeast: Application to Sparkling Wine Processing

Kevin Crouvisier-Urion , Pascale Winckler , Aurélie Lagorce-Tachon , Hervé Alexandre , Thomas Karbowiak

American Journal of Enology and Viticulture, 2018, 69 (2), pp.182-187. ⟨10.5344/ajev.2017.17080⟩

Article dans une revue hal-02484229v1
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The vesicular transfer of CLIC1 from glioblastoma to microvascular endothelial cells requires TRPM7

Dominique Thuringer , Gaetan Chanteloup , Pascale Winckler , Carmen Garrido

Oncotarget, 2018, 9 (70), pp.33302-33311. ⟨10.18632/oncotarget.26048⟩

Article dans une revue hal-02348814v1

Cellular imaging using BODIPY-, pyrene- and phthalocyanine- based conjugates

Faustine Bizet , Martin Ipuy , Yann Bernhard , Vivian Lioret , Pascale Winckler et al.

Bioorganic and Medicinal Chemistry, 2018, 26 (2), pp.413 - 420. ⟨10.1016/j.bmc.2017.11.050⟩

Article dans une revue hal-01687238v1

Impact of the homogenization process on the structure and antioxidant properties of chitosan-lignin composite films

Kevin Crouvisier-Urion , Aurélie Lagorce-Tachon , Camille Lauquin , Pascale Winckler , Wirongrong Tongdeesoontorn et al.

Food Chemistry, 2017, 236, pp.120-126. ⟨10.1016/j.foodchem.2017.03.094⟩

Article dans une revue hal-01510433v1

Biobased Composite Films from Chitosan and Lignin: Antioxidant Activity Related to Structure and Moisture

Kevin Crouvisier-Urion , Philippe Bodart , Pascale Winckler , Jésus Raya , Régis D. Gougeon et al.

ACS Sustainable Chemistry & Engineering, 2016, 4 (12), pp.6371 - 6381. ⟨10.1021/acssuschemeng.6b00956⟩

Article dans une revue hal-01468831v1

Surviving the heat: heterogeneity of response in S accharomyces cerevisiae provides insight into thermal damage to the membrane

Stéphane Guyot , Patrick Gervais , Michael Young , Pascale Winckler , Jennifer Dumont et al.

Environmental Microbiology, 2015, 17 (8), pp.2982-2992. ⟨10.1111/1462-2920.12866⟩

Article dans une revue hal-02290604v1

Visualization of RNA-Quadruplexes in Live Cells

Aurélien Laguerre , Kyle Hukezalie , Pascale Winckler , Fares Katranji , Gaëtan Chanteloup et al.

Journal of the American Chemical Society, 2015, 137 (26), pp.8521-8525. ⟨10.1021/jacs.5b03413⟩

Article dans une revue hal-02125776v1

Physico-chemical state influences in vitro release profile of curcumin from pectin beads

an Thi-Binh Nguyen , Pascale Winckler , Pauline Loison , Yves Waché , Odile Chambin

Colloids and Surfaces B: Biointerfaces, 2014, 121, pp.290-298. ⟨10.1016/j.colsurfb.2014.05.023⟩

Article dans une revue istex hal-02877714v1

Harnessing medically relevant metals onto water-soluble subphthalocyanines: towards bimodal imaging and theranostics

Yann Bernhard , Pascale Winckler , Jean-Marie Perrier-Cornet , Richard A Decréau

Dalton Transactions, 2014, 44 (7), pp.3200 - 3208. ⟨10.1039/c4dt03536d⟩

Article dans une revue hal-03263267v1

Subphthalocyanines: addressing water-solubility, nano-encapsulation, and activation for optical imaging of B16 melanoma cells

Yann Bernhard , Pascale Winckler , Remi Chassagnon , Philippe Richard , Élodie Gigot et al.

Chemical Communications, 2014, 50 (90), pp.13975-13978. ⟨10.1039/c4cc05503a⟩

Article dans une revue hal-03262940v1
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Identification and super-resolution imaging of ligand-activated receptor dimers in live cells

Pascale Winckler , Lydia Lartigue , Gregory Giannone , Francesca de Giorgi , François Ichas et al.

Scientific Reports, 2013, 3, pp.2387. ⟨10.1038/srep02387⟩

Article dans une revue hal-00909281v1

Multiphoton Cascade Absorption in Single Molecule Fluorescence Saturation Spectroscopy

Pascale Winckler , Rodolphe Jaffiol

Analytical Chemistry, 2013, 85 (9), pp.4735-4744. ⟨10.1021/ac400454f⟩

Article dans une revue hal-02404888v1

Microfluidity mapping using fluorescence correlation spectroscopy: A new way to investigate plasma membrane microorganization of living cells

Pascale Winckler , Aurélie Cailler , Régis Deturche , Pierre Jeannesson , Hamid Morjani et al.

Biochimica et Biophysica Acta:Biomembranes, 2012, 1818 (11), pp.2477-2485. ⟨10.1016/j.bbamem.2012.05.018⟩

Article dans une revue hal-02383196v1

Microscopie OPTIR pour la caractérisation des microorganismes d'intérêt alimentaire.

Pascale Winckler , Maxime Pacheco , Matéo Lavaud , Jonathan Dikec , Jean-Marie Perrier-Cornet

Journées Spectroscopie infrarouge O-PTIR, Jul 2025, Le Mans, France

Communication dans un congrès hal-05264282v1

Microscopie OPTIR : application à la microspectroscopie des microorganismes.

Pascale Winckler , Maxime Pacheco , Matéo Lavaud , Jonathan Dikec , Jean-Marie Perrier-Cornet

31ièmes Journées scientifiques 2025 du GFSV, May 2025, St Malo, France

Communication dans un congrès hal-05264297v1

The pore-forming toxin Candidalysin dampens the autophagy-related plasma membrane stress response during Candida albicans invasion of epithelial cells.

Pierre Lapaquette , Amandine Ducreux , Louise Basmaciyan , Fabienne Bon , Pascale Winckler et al.

Symposium HARMI, Sep 2025, Dijon, France

Communication dans un congrès hal-05515819v1

Exploration of the mechanisms leading to the cell death of Brettanomyces bruxellensis induced by amphidinols derived from marine microalgae.

Chloé Abry , Pascale Winckler , Laure Avoscan , Aline Bonnotte , Emmanuel Denimal et al.

Cytométrie (AFC), Nov 2025, Dijon, France

Communication dans un congrès hal-05515560v1

MICROSCOPIE VIBRATIONNELLE OPTIR : APPLICATION A LA CARACTERISATION DE LA GRAINE DE BRASSICA JUNCEA.

Pascale Winckler , Bonnot Emma , Lavaud Matéo , Jean-Marie Perrier-Cornet , Dominique Champion

Congrès annuel de l'Association Française d'Histotechnologie 2023, Plateforme DImaCell; Association Française d'histotechnologie, Jun 2023, Dijon, France. pp.93-106, ⟨10.25830/afh.rfh.2024.36.1.93⟩

Communication dans un congrès hal-05264308v1

Heterogeneity of response to heat stress in Saccharomyces cerevisiae

Stéphane Guyot , Dumont, J , Patrick Gervais , Young, M , Pascale Winckler et al.

32nd International Specialized Symposium on Yeasts, Sep 2015, Perugia, France

Communication dans un congrès hal-05289791v1

How dehydration with glycerol protects bacteria cell membranes against deleterious effects of supercooling

Hélène Simonin , Pascale Winckler , Alexis Gros , Jean-Marie Perrier-Cornet , Patrick Gervais

Cryo 2015, 52nd annual meeting of the society for cryobiology, Jun 2015, Ostrava, Czech Republic. pp.549, ⟨10.1016/j.cryobiol.2015.10.051⟩

Communication dans un congrès istex hal-02316221v1

Nonradiative Excitation Fluorescence Correlation Spectroscopy

Rodolphe Jaffiol , Cyrille Vézy , Pascale Winckler

1st Annual Conference of the COST Action MP1302 Nanospectroscopy, Mar 2014, Tübingen, Germany

Communication dans un congrès hal-02531271v1

Single molecule fluorescence saturation spectroscopy

Rodolphe Jaffiol , Pascale Winckler

SPIE BiOS, Feb 2014, San Francisco, United States. pp.89500C, ⟨10.1117/12.2037029⟩

Communication dans un congrès hal-02531216v1

Multiphoton Cascade Absorption in Single Molecule Fluorescence Saturation Spectroscopy

Pascale Winckler , Rodolphe Jaffiol

International Conference of Photochemistry (ICP) 2013, Jul 2013, Leuven, Belgium

Communication dans un congrès hal-02531233v1

Multi-photon cascade absorption in single molecule fluorescence saturation spectroscopy

Rodolphe Jaffiol , Pascale Winckler

US-French nanooptics workshop, Nov 2013, Troyes, France

Communication dans un congrès hal-02531273v1

Non-radiative Excitation Fluorescence Microscopy

Rodolphe Jaffiol , Pascale Winckler , Cyrille Vézy , Marcelina Cardoso dos Santos

4ème Colloque du club de l'Adhérence Cellulaire, May 2012, Talence, France

Communication dans un congrès hal-02531279v1

Non-radiative Excitation Fluorescence Microscopy

Rodolphe Jaffiol , Pascale Winckler , Cyrille Vézy , Marcelina Cardoso dos Santos

1st Workshop Cancer Cells on-Chip: State of the Art and future developments, Jun 2012, Lyon, France

Communication dans un congrès hal-02531275v1
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Rapid identification of bacterial spores by Raman and OPTIR infrared spectroscopy using chemometrics and machine learning

Elie Sarkees , Marie-Claire de Vos Franzin , Pascale Winckler , Jean-Marie Perrier-Cornet

Chimiométrie XXVeme, Feb 2026, Nancy, France

Poster de conférence hal-05512962v1

Microscopic and spectroscopic exploration of brewer’s spent grain fermentation by Aspergillus oryzae for kojic acid synthesis

Paul Lagneaux , Nathan Widjaja , Muhammad Hassan , Pascale Winckler , Yves Waché

Forum des Jeunes Chercheurs, Jun 2025, Besançon, France

Poster de conférence hal-05318276v1
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Microscopic and Spectroscopic exploration of brewer’s spent grain fermentation by Aspergillus oryzae for kojic acid synthesis

Paul Lagneaux , Nathan Widjaja , Muhammad Hassan , Pascale Winckler , Yves Waché

Cosm'ing 2025, Jun 2025, Saint-Malo, France

Poster de conférence hal-05172760v1

The pore-forming toxin Candidalysin dampens the autophagy-related plasma membrane stress response during Candida albicans invasion of epithelial cells

Pierre Lapaquette , Amandine Ducreux , Louise Basmaciyan , Fabienne Bon , Pascale Winckler et al.

CFATG12, 12th Scientific days on Autophagy, Mar 2025, Dijon, France

Poster de conférence hal-05515811v1

OPTIR : infrared microspectroscopy for advanced characterization of microorganisms

Pascale Winckler , Maxime Pacheco , Elie Sarkees , Jonathan Dikec , Jean-Marie Perrier-Cornet

Symposium HARMI 2025, Sep 2025, Dole, France

Poster de conférence hal-05264271v1
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Using CRISPR/Cas platform for Genetic Modification of Commercial Saccharomyces cerevisiae strains

C. Eicher , Géraldine L. Klein , Pascale Winckler , Jean-Luc Parrou , Hervé Alexandre et al.

OENO-IVAS 2019, Jun 2019, Bordeaux, France

Poster de conférence hal-02466806v1

Milk protein-pectin beads : a novel means for curcumin encapsulation.

Nguyen T.A , Huynh T.U , Pascale Winckler , Yves Waché , M. Subirade et al.

1st European Conference on Pharmaceutics – Drug Delivery, Apr 2015, Reims, France

Poster de conférence hal-05272787v1

Comparison of m-PEG-PCL polymersomes size measurements by 3 optical techniques : DLS, NTA and two-photon microscopy.

Inkichari M , C.H. Brachais , Bouvier C , Ali Assifaoui , Pascale Winckler et al.

1st European Conference on Pharmaceutics – Drug Delivery, Apr 2015, Reims, France

Poster de conférence hal-05272798v1