patrice gouet

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Prix Nobel de chimie 2024: David Baker, Demis Hassabis et John M. Jumper

Stéphanie Aguéro-Pizzolo , Patrice Gouet , Emmanuel Bettler
Médecine/Sciences, 2025, 41 (4), pp.367-373. ⟨10.1051/medsci/2025060⟩
Article dans une revue hal-05050517 v1
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FoldScript: a web server for the efficient analysis of AI-generated 3D protein models

Xavier Robert , Christophe Guillon , Patrice Gouet
Nucleic Acids Research, 2025, 23rd annual Nucleic Acids Research Web Server Issue 2025, ⟨10.1093/nar/gkaf326⟩
Article dans une revue hal-05049646 v1
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“It’s Only a Model”: When Protein Structure Predictions Need Experimental Validation, the Case of the HTLV-1 Tax Protein

Christophe Guillon , Xavier Robert , Patrice Gouet
Pathogens, 2024, 13 (3), pp.241. ⟨10.3390/pathogens13030241⟩
Article dans une revue (article de synthèse) hal-04497855 v1
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Unveiling a Shield of Hope: A Novel Multiepitope-Based Immunogen for Cross-Serotype Cellular Defense against Dengue Virus

Nilanshu Manocha , Daphné Laubreton , Xavier Robert , Jacqueline Marvel , Virginie Gueguen-Chaignon et al.
Vaccines, 2024, 12 (3), pp.316. ⟨10.3390/vaccines12030316⟩
Article dans une revue hal-04902274 v1
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Tetanus Toxin Fragment C: Structure, Drug Discovery Research and Production

Caroline Bayart , Angélique Mularoni , Nada Hemmani , Soumeya Kerachni , Joachim Jose et al.
Pharmaceuticals, 2022, 15 (6), pp.756. ⟨10.3390/ph15060756⟩
Article dans une revue hal-03718458 v1
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The C-Terminal Domain of HIV-1 Integrase: A Swiss Army Knife for the Virus?

Cecilia Rocchi , Patrice Gouet , Vincent Parissi , Francesca Fiorini
Viruses, 2022, 14 (7), pp.1397. ⟨10.3390/v14071397⟩
Article dans une revue hal-03733732 v1
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Specific Xray diffraction patterns of membrane proteins caused by secondary structure collinearity

Juliette Martin , Xavier Robert , Patrice Gouet , Pierre Falson , Vincent Chaptal
Biochimica et Biophysica Acta:Biomembranes, 2022, pp.184065. ⟨10.1016/j.bbamem.2022.184065⟩
Article dans une revue hal-03796617 v1
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Structure–function analysis of pectate lyase Pel3 reveals essential facets of protein recognition by the bacterial type 2 secretion system.

Camille Pineau , Natalia Guschinskaya , Isabelle R Gonçalves , Florence Ruaudel , Xavier Robert et al.
Journal of Biological Chemistry, 2021, pp.100305. ⟨10.1016/j.jbc.2021.100305⟩
Article dans une revue hal-03143879 v1
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Identification of a Potential Inhibitor of the FIV p24 Capsid Protein and Characterization of Its Binding Site

Mathieu Long , François-Xavier Cantrelle , Xavier Robert , Emmanuelle Boll , Natalia Sierra et al.
Biochemistry, 2021, 60 (24), pp.1896-1908. ⟨10.1021/acs.biochem.1c00228⟩
Article dans une revue hal-03280829 v1
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In vitro, in cellulo and structural characterizations of the interaction between the integrase of Porcine Endogenous Retrovirus A/C and proteins of the BET family

Kathy Gallay , Guillaume Blot , Margaux Chahpazoff , Halima Yajjou-Hamalian , Marie-Pierre Confort et al.
Virology, 2019, 532, pp.69-81. ⟨10.1016/j.virol.2019.04.002⟩
Article dans une revue hal-02359028 v1
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Human H4 tail stimulates HIV-1 integration through binding to the carboxy-terminal domain of integrase

Eric Mauro , Paul Lesbats , Delphine Lapaillerie , Stéphane Chaignepain , Benoit Maillot et al.
Nucleic Acids Research, 2019, 47 (7), pp.3607-3618. ⟨10.1093/nar/gkz091⟩
Article dans une revue hal-02122315 v1

PASTA repeats of the protein kinase StkP interconnect cell constriction and separation of Streptococcus pneumoniae

L. Zucchini , C. Mercy , Ps. Garcia , C. Cluzel , V. Gueguen-Chaignon et al.
Nature Microbiology, 2018, 3 (2), pp.197-209. ⟨10.1038/s41564-017-0069-3⟩
Article dans une revue hal-01887855 v1
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Au courant computation of the PDB to audit diffraction anisotropy of soluble and membrane proteins

Xavier Robert , Josiane Kassis-Sahyoun , Nicoletta Ceres , Juliette Martin , Michael R Sawaya et al.
Data in Brief, 2018, 19, pp.753-757. ⟨10.1016/j.dib.2018.05.072⟩
Article dans une revue hal-02326014 v1
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Identification and visualization of protein binding regions with the ArDock server

Sébastien Reille , Mélanie Garnier , Xavier Robert , Patrice Gouet , Juliette Martin et al.
Nucleic Acids Research, 2018, 46 (W1), pp.W417-W422. ⟨10.1093/nar/gky472⟩
Article dans une revue hal-02344721 v1

Structural model of the full-length Ser/Thr protein kinase StkP from S . pneumoniae and its recognition of peptidoglycan fragments

Benedetta Righino , Frédéric Galisson , Davide Pirolli , Serena Vitale , Stéphane Réty et al.
Journal of Biomolecular Structure and Dynamics, 2017, 36 (14), pp.3666-3679. ⟨10.1080/07391102.2017.1395767⟩
Article dans une revue hal-02324061 v1
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Modulation of the functional association between the HIV-1 intasome and the nucleosome by histone amino-terminal tails

Mohamed S Benleulmi , Julien Matysiak , Xavier Robert , Csaba Miskey , Eric Mauro et al.
Retrovirology, 2017, 14 (1), pp.54. ⟨10.1186/s12977-017-0378-x⟩
Article dans une revue hal-03532360 v1
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X-ray diffraction reveals the intrinsic difference in the physical properties of membrane and soluble proteins

Xavier Robert , Josiane Kassis-Sahyoun , Nicoletta Ceres , Juliette Martin , Michael R Sawaya et al.
Scientific Reports, 2017, 7 (1), ⟨10.1038/s41598-017-17216-1⟩
Article dans une revue hal-02329431 v1
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The Substrate-free and -bound Crystal Structures of the Duplicated Taurocyamine Kinase from the Human Parasite Schistosoma mansoni

Romain Merceron , Ayman M Awama , Roland Montserret , Olivier Marcillat , Patrice Gouet
Journal of Biological Chemistry, 2015, 290 (20), ⟨10.1074/jbc.M114.628909⟩
Article dans une revue hal-04902020 v1

A Staggered Decameric Assembly of Human C-Reactive Protein Stabilized by Zinc Ions Revealed by X-ray Crystallography

Christophe Guillon , Ulrick Bigouagou , Christelle Folio , Pascale Jeannin , Yves Delneste et al.
Protein and Peptide Letters, 2015, 22 (3), pp.248 - 255. ⟨10.2174/0929866522666141231111226⟩
Article dans une revue hal-01392233 v1

Porcine endogenous retrovirus-A/C: biochemical properties of its integrase and susceptibility to raltegravir

A. Demange , Halima Yajjou-Hamalian , Kathy Gallay , Catherine Luengo , V. Beven et al.
Journal of General Virology, 2015, 96 (10), pp.3124-30. ⟨10.1099/jgv.0.000236⟩
Article dans une revue hal-02192915 v1

Substrate recognition by the bacterial type II secretion system: more than a simple interaction

C. Pineau , Natalia Guschinskaya , X. Robert , P. Gouet , L. Ballut et al.
Molecular Microbiology, 2014, 94 (1), pp.126-40. ⟨10.1111/mmi.12744⟩
Article dans une revue hal-02001308 v1
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Deciphering key features in protein structures with the new ENDscript server

Xavier Robert , Patrice Gouet
Nucleic Acids Research, 2014, Issue W1, 42 (W1), pp.W320-W324. ⟨10.1093/nar/gku316⟩
Article dans une revue hal-04909755 v1

Biophysical characterization and crystal structure of the Feline Immunodeficiency Virus p15 matrix protein

Jennifer Serrière , Xavier Robert , Magali Perez , Patrice Gouet , Christophe Guillon
Retrovirology, 2013, 10 (1), pp.64. ⟨10.1186/1742-4690-10-64⟩
Article dans une revue hal-02121708 v1

In vitro functional analyses of the human immunodeficiency virus type 1 (HIV-1) integrase mutants give new insights into the intasome assembly

Coralie Cellier , Karen Moreau , Kathy Gallay , Allison Ballandras , Patrice Gouet et al.
Virology, 2013, 439 (2), pp.97-104. ⟨10.1016/j.virol.2013.02.001⟩
Article dans une revue hal-02643414 v1

Biophysical characterization of the feline immunodeficiency virus p24 capsid protein conformation and in vitro capsid assembly.

Jennifer Serrière , Daphna Fenel , Guy Schoehn , Patrice Gouet , Christophe Guillon
PLoS ONE, 2012, 8 (2), pp.e56424. ⟨10.1371/journal.pone.0056424⟩
Article dans une revue hal-01179737 v1

Fab′-Induced Folding of Antigenic N-Terminal Peptides from Intrinsically Disordered HIV-1 Tat Revealed by X-ray Crystallography

Jennifer Serrière , Jean-Marc Dugua , Marc Bossus , Bernard Verrier , Richard Haser et al.
Journal of Molecular Biology, 2011, 405 (1), pp.33-42. ⟨10.1016/j.jmb.2010.10.033⟩
Article dans une revue istex hal-02121733 v1

Functional analyses of mutants of the central core domain of an Avian Sarcoma/Leukemia Virus integrase

Julie Charmetant , Karen Moreau , Kathy Gallay , Allison Ballandras , Patrice Gouet et al.
Virology, 2011, 421 (1), pp.42-50. ⟨10.1016/j.virol.2011.09.008⟩
Article dans une revue hal-02643492 v1
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A crystal structure of the catalytic core domain of an avian sarcoma and leukemia virus integrase suggests an alternate dimeric assembly

Allison Ballandras , Karen Moreau , Xavier Robert , Marie-Pierre Confort , Romain Merceron et al.
PLoS ONE, 2011, 6 (8), pp.1 - 10. ⟨10.1371/journal.pone.0023032⟩
Article dans une revue hal-02645754 v1

UV and X-ray structural studies of a 101-residue long Tat protein from a HIV-1 primary isolate and of its mutated, detoxified, vaccine candidate.

Marine Foucault , Katia Mayol , Véronique Receveur-Bréchot , Marie-Claire Bussat , Christine Klinguer-Hamour et al.
Proteins - Structure, Function and Bioinformatics, 2010, 78 (6), pp.1441-56. ⟨10.1002/prot.22661⟩
Article dans une revue istex hal-00473775 v1

The Extended Conformation of the 2.9-Å Crystal Structure of the Three-PASTA Domain of a Ser/Thr Kinase from the Human Pathogen Staphylococcus aureus

Patricia Paracuellos , Allison Ballandras , Xavier Robert , Richard Kahn , Mireille Hervé et al.
Journal of Molecular Biology, 2010, 404 (5), pp.847-858. ⟨10.1016/j.jmb.2010.10.012⟩
Article dans une revue istex hal-04246133 v1

Crystallization and initial X-ray diffraction study of the three PASTA domains of the Ser/Thr kinase Stk1 from the human pathogen Staphylococcus aureus

Patricia Paracuellos , Allison Ballandras , Xavier Robert , Alain Cozzone , Bertrand Duclos et al.
Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 2009, 65 (11), pp.1187-1189. ⟨10.1107/s174430910904250x⟩
Article dans une revue hal-04246128 v1

UV and X-ray structural studies of a 101-residue long Tat protein from a HIV-1 primary isolate and of its mutated, detoxified, vaccine candidate

Marine Foucault , Katia Mayol , Vã©ronique Receveur-Brã©chot , Marie-Claire Bussat , Christine Klinguer-Hamour et al.
Proteins - Structure, Function and Bioinformatics, 2009, pp.1441-1456. ⟨10.1002/prot.22661⟩
Article dans une revue istex hal-02121744 v1

Mapping of immunogenic and protein-interacting regions at the surface of the seven-bladed beta-propeller domain of the HIV-1 cellular interactor EED.

D. Rakotobe , S. Violot , Ss Hong , P. Gouet , P. Boulanger
Virol J, 2008, 5, pp.32-32
Article dans une revue hal-00315182 v1
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The crystal structure of pectate lyase peli from soft rot pathogen Erwinia chrysanthemi in complex with its substrate

Christophe Crezé , Sandra Castang , Emmanuel Derivery , Richard Haser , Nicole Hugouvieux-Cotte-Pattat et al.
Journal of Biological Chemistry, 2008, 283 (26), pp.18260-18268. ⟨10.1074/jbc.M709931200⟩
Article dans une revue hal-00315227 v1

Crystallization and X-ray analysis of the Schistosoma mansoni guanidino kinase

Ayman M. Awama , Patricia Paracuellos , Sabine Laurent , Colette Dissous , Olivier Marcillat et al.
Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 2008, 64 (9), pp.854-857. ⟨10.1107/S1744309108025979⟩
Article dans une revue hal-00445416 v1

Structure of a d(TGGGGT) quadruplex crystallized in the presence of Li(+) ions.

C. Creze , B. Rinaldi , R. Haser , Philippe Bouvet , P. Gouet
Acta crystallographica Section D : Structural biology [1993-..], 2007, 63 (Pt 6), pp.682-688
Article dans une revue hal-00337638 v1

Direct evidence for the modulation of the activity of the Erwinia chrysanthemi quorum-sensing regulator ExpR by acylhomoserine lactone pheromone.

S. Castang , S. Reverchon , P. Gouet , W. Nasser
Journal of Biological Chemistry, 2006, 281, pp.29972-29987
Article dans une revue hal-00315156 v1

Crystallization and preliminary X-ray diffraction studies of two thermostable alpha-galactosidases from glycoside hydrolase family 36.

M. Foucault , H. Watzlawick , R. Mattes , R. Haser , P. Gouet
Acta crystallographica Section F : Structural biology communications [2014-..], 2006, 62, pp.100-103
Article dans une revue hal-00313527 v1

Structure of a full length psychrophilic cellulase from Pseudoalteromonas haloplanktis revealed by X-ray diffraction and small angle X-ray scattering.

S. Violot , N. Aghajari , M. Czjzek , G. Feller , Gk Sonan et al.
Journal of Molecular Biology, 2005, 348, pp.1211-1224
Article dans une revue hal-00313535 v1

ESPript/ENDscript: sequence and 3D information from protein structures

Patrice Gouet , Xavier Robert , Emmanuel Courcelle
Acta Crystallographica Section A : Foundations of Crystallography [1968-2013], 2005, 61 (a1), pp.c42-c43. ⟨10.1107/S0108767305098211⟩
Article dans une revue hal-04909788 v1

N-Sulfonyl homoserine lactones as antagonists of bacterial quorum sensing.

S. Castang , B. Chantegrel , C. Deshayes , R. Dolmazon , P. Gouet et al.
Bioorganic and Medicinal Chemistry Letters, 2004, 14, pp.5145-5149
Article dans une revue hal-00313537 v1

Mutational analyses of the core domain of Avian Leukemia and Sarcoma Viruses integrase: critical residues for concerted integration and multimerization.

K. Moreau , C. Faure , S. Violot , P. Gouet , Ghislain Verdier et al.
Virology, 2004, 318, pp.566-581
Article dans une revue hal-00314279 v1

Mutational analyses of the core domain of Avian Leukemia and Sarcoma Viruses integrase : critical residues for concerted integration and multimerization

Karen Moreau , Claudine Faure , Sebastien Violot , Patrice Gouet , Gérard Verdier et al.
Virology, 2004, 318 (2), pp.566-581. ⟨10.1016/j.virol.2003.09.037⟩
Article dans une revue hal-02679348 v1

N-Sulfonyl homoserine lactones as antagonists of bacterial quorum sensing.

Sandra Castang , Bernard Chantegrel , Christian Deshayes , René Dolmazon , Patrice Gouet et al.
Bioorganic and Medicinal Chemistry Letters, 2004, 14, pp.5145-5149. ⟨10.1016/j.bmcl.2004.07.088⟩
Article dans une revue istex hal-00015818 v1

Structural studies of Proteus mirabilis catalase in its ground state, oxidized state and in complex with formic acid.

P. Andreoletti , A. Pernoud , G. Sainz , P. Gouet , Hm Jouve
Acta Crystallogr D Biol Crystallogr, 2003, 59, pp.2163-2168
Article dans une revue hal-00314280 v1

ESPript/ENDscript: Extracting and rendering sequence and 3D information from atomic structures of proteins.

P. Gouet , X. Robert , E. Courcelle
Nucleic Acids Research, 2003, 31, pp.3320-3323
Article dans une revue hal-00314281 v1

Probing the role of divalent metal ions in a bacterial psychrophilic metalloprotease: binding studies of an enzyme in the crystalline state by x-ray crystallography.

S. Ravaud , P. Gouet , R. Haser , N. Aghajari
Journal of Bacteriology, 2003, 185, pp.4195-4203
Article dans une revue hal-00313540 v1

ENDscript: a workflow to display sequence and structure information.

P. Gouet , E. Courcelle
Bioinformatics, 2002, 18, pp.767-768
Article dans une revue hal-00313126 v1

Further insights into the mechanism of function of the response regulator CheY from crystallographic studies of the CheY--CheA(124--257) complex.

P. Gouet , N. Chinardet , M. Welch , V. Guillet , S. Cabantous et al.
Acta Crystallogr D Biol Crystallogr, 2001, 57, pp.44-51
Article dans une revue hal-00314283 v1

Translocation portals for the substrates and products of a viral transcription complex: the bluetongue virus core.

Jm Diprose , Jn Burroughs , Gc Sutton , A. Goldsmith , P. Gouet et al.
EMBO Journal, 2001, 20, pp.7229-7239
Article dans une revue hal-00314282 v1

Functional dissection of the major structural protein of bluetongue virus: identification of key residues within VP7 essential for capsid assembly.

Ck Limn , N. Staeuber , K. Monastyrskaya , P. Gouet , Pascal Roy
Journal of Virology, 2000, 74, pp.8658-8669
Article dans une revue hal-00314284 v1

ESPript: analysis of multiple sequence alignments in PostScript.

P. Gouet , E. Courcelle , Di Stuart , F. Metoz
Bioinformatics, 1999, 15, pp.305-308
Article dans une revue hal-00314288 v1
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Conformational changes induced by phosphorylation of the FixJ receiver domain

Catherine Birck , Lionel Mourey , Patrice Gouet , Béatrice Fabry , Jörg Schumacher et al.
Structure, 1999, 7 (12), pp.1505-1515. ⟨10.1016/s0969-2126(00)88341-0⟩
Article dans une revue hal-03004414 v1

The highly ordered double-stranded RNA genome of bluetongue virus revealed by crystallography.

P. Gouet , Jm Diprose , Jm Grimes , R. Malby , Jn Burroughs et al.
Cell, 1999, 97, pp.481-490. ⟨10.1016/s0092-8674(00)80758-8⟩
Article dans une revue hal-00314287 v1
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Structural transitions in the FixJ receiver domain

Patrice Gouet , Béatrice Fabry , Valérie Guillet , Catherine Birck , Lionel Mourey et al.
Structure, 1999, 7 (12), pp.1517-1526. ⟨10.1016/S0969-2126(00)88342-2⟩
Article dans une revue hal-03004398 v1

Bluetongue virus: the role of synchrotron radiation

Jm Diprose , Jm Grimes , P. Gouet , R. Malby , Jn Burroughs et al.
Journal of Synchrotron Radiation, 1999, 6, pp.865-874
Article dans une revue hal-00314577 v1

The atomic structure of the bluetongue virus core.

Jm Grimes , Jn Burroughs , P. Gouet , Jm Diprose , R. Malby et al.
Nature, 1998, 395, pp.470-478. ⟨10.1038/26694⟩
Article dans une revue hal-00314291 v1

Structural studies of orbivirus particles.

Di Stuart , P. Gouet , J. Grimes , R. Malby , J. Diprose et al.
Arch Virol Suppl, 1998, 14, pp.235-250
Article dans une revue hal-00314290 v1

Structures of orbivirus VP7: implications for the role of this protein in the viral life cycle.

Ak Basak , Jm Grimes , P. Gouet , Pascal Roy , Di Stuart
Structure, 1997, 5, pp.871-883
Article dans une revue hal-00314293 v1

Structural analysis of compound I in hemoproteins: study on Proteus mirabilis catalase.

Hm Jouve , P. Andreoletti , P. Gouet , J. Hajdu , J. Gagnon
Biochimie, 1997, 79, pp.667-671
Article dans une revue hal-00314292 v1

Crystal structure of the top domain of African horse sickness virus VP7: comparisons with bluetongue virus VP7.

Ak Basak , P. Gouet , J. Grimes , Pascal Roy , D. Stuart
Journal of Virology, 1996, 70, pp.3797-3806
Article dans une revue hal-00314295 v1

Ferryl intermediates of catalase captured by time-resolved Weissenberg crystallography and UV-VIS spectroscopy.

P. Gouet , Hm Jouve , Pa Williams , I. Andersson , P. Andreoletti et al.
Nat Struct Biol, 1996, 3, pp.951-956
Article dans une revue hal-00314294 v1

Simulations of electron transfer in the NADPH-bound catalase from Proteus mirabilis PR.

Dj Bicout , Mj Field , P. Gouet , Hm Jouve
BBA - Biochimica et Biophysica Acta, 1995, 1252, pp.172-176
Article dans une revue hal-00314296 v1

Crystal structure of Proteus mirabilis PR catalase with and without bound NADPH.

P. Gouet , Hm Jouve , O. Dideberg
Journal of Molecular Biology, 1995, 249, pp.933-954
Article dans une revue hal-00314298 v1

Viral envelope glycoproteins swing into action.

D. Stuart , P. Gouet
Structure, 1995, 3, pp.645-648
Article dans une revue hal-00314297 v1

Pressure and propylene carbonate denaturation of native and "aged" phosphorylated cholinesterase.

P. Masson , P. Gouet , C. Clery
Journal of Molecular Biology, 1994, 238, pp.466-478
Article dans une revue hal-00314299 v1

Recombinant human butyrylcholinesterase G390V, the fluoride-2 variant, expressed in Chinese hamster ovary cells, is a low affinity variant.

P. Masson , S. Adkins , P. Gouet , O. Lockridge
Journal of Biological Chemistry, 1993, 268, pp.14329-14341
Article dans une revue hal-00314300 v1

Crystallization and crystal packing of Proteus mirabilis PR catalase

Hélène-Marie Jouve , Patrice Gouet , Nassira Boudjada , Georges Buisson , Richard Kahn et al.
Journal of Molecular Biology, 1991, 221 (4), pp.1075-1077. ⟨10.1016/0022-2836(91)90918-V⟩
Article dans une revue istex hal-04541774 v1

Crystallization and crystal packing of Proteus mirabilis PR catalase.

Hm Jouve , P. Gouet , N. Boudjada , G. Buisson , R. Kahn et al.
Journal of Molecular Biology, 1991, 221, pp.1075-1077
Article dans une revue hal-00314301 v1

Blood poisonings at slaughter and their consequences

Jean-Claude Labadie , P. Gouet , J. Fournaud
Zentralblatt für Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. 1. Abteilung. Originale. Reihe B, Hygiene, Präventive Medizin, 1977, 1B (164), pp.390-396
Article dans une revue hal-02731380 v1