PL

Patrice Le Pape

134
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Publications

Publications

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Respiratory management of critically ill pneumocystis pneumonia patients: a multicenter retrospective study

Florian Reizine , Vicky Stiegler , Romain Lécuyer , Benoit Tessoulin , Marie Gallais et al.

Annals of Intensive Care, 2025, 15, pp.114. ⟨10.1186/s13613-025-01503-6⟩

Article dans une revue hal-05334494v1

Pharmacophore-guided optimization of the hit compound CTN1122 in the design of promising imidazo[1,2- a ]pyrazine derivatives targeting the casein kinase 1 for antileishmanial therapy

Lhana Tisseur , Cédric Logé , Sandrine Cojean , Khadidiatou Gassama , Lilian Karcher et al.

RSC Medicinal Chemistry, 2025, 16, pp.3746-3763. ⟨10.1039/d5md00257e⟩

Article dans une revue hal-05173262v1
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Synthesis and Biological Evaluation of Itraconazole Derivatives: Design in an Old Scaffold

Shuai Zhong , Apollonia Kalamatianou , Gonzalo Scalese , Cillian O’beirne , Marta Redrado et al.

Inorganic Chemistry, 2025, 64 (31), pp.16192-16203. ⟨10.1021/acs.inorgchem.5c02730⟩

Article dans une revue hal-05211856v1
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Hyperinfection with Anisakis simplex sensu stricto: observations from a cluster of two cases in France

Manon Robert , Maureen Duflot , Fakhri Jeddi , Carelle Koudougou , Louise Durand et al.

Food and Waterborne Parasitology, 2025, 40, pp.e00282. ⟨10.1016/j.fawpar.2025.e00282⟩

Article dans une revue hal-05295420v1

Elevating fungal care: bridging Brazil’s healthcare practices to global standards

Jon Salmanton-García , Diego Falci , Oliver Cornely , Alessandro Pasqualotto , Afonso Barth et al.

Microbiology Spectrum, 2025, 13 (4), pp.102799. ⟨10.1128/spectrum.02112-24⟩

Article dans une revue hal-05169393v1
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Clade Distinction and Tracking of Clonal Spread by Fourier‐Transform Infrared Spectroscopy in Multicenter <i>Candida</i> (<i>Candidozyma</i>) <i>auris</i> Outbreak

Camylla C de Melo , Halana L N L de Oliveira , Bruna R Souza , Carla V R Moura , Rodrigo Oliveira et al.

Mycoses, 2025, 68 (7), pp.e70085. ⟨10.1111/myc.70085⟩

Article dans une revue hal-05334348v1
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A one health perspective on Diutina catenulata: Phenotypic traits, stress sensitivity, and virulence across diverse isolates

Ianca Karine Prudencio de Albuquerque , Florent Morio , Marjorie Albassier , Luc Baron , Léa Duchesne et al.

Journal of Medical Mycology = Journal de Mycologie Médicale, 2025, 35, pp.101583. ⟨10.1016/j.mycmed.2025.101583⟩

Article dans une revue hal-05329491v1

Investigating the C2 Modulation of the Imidazo[1,2‐ a ]pyrazine‐Based Hit Compound CTN1122: Synthesis, in vitro Antileishmanial Activity, Cytotoxicity and Casein Kinase 1 Inhibition

Lhana Tisseur , Sandrine Cojean , Khadidiatou Gassama , Cédric Logé , Fabrice Pagniez et al.

ChemMedChem, 2025, 20 (6), pp.e202400862. ⟨10.1002/cmdc.202400862⟩

Article dans une revue hal-05181232v1

Chemical Composition, Antifungal, Antioxidant, and Hemolytic Activities of Moroccan Thymus capitatus Essential Oil

Amina Amakran , Meriem Hamoudane , Fabrice Pagniez , Ahmed Lamarti , Carine Picot et al.

Chemistry and Biodiversity, 2024, 21 (9), pp.e202300563. ⟨10.1002/cbdv.202300563⟩

Article dans une revue hal-04805121v1

Precise genome editing underlines the distinct contributions of mutations in ERG11 , ERG3 , MRR1 , and TAC1 genes to antifungal resistance in Candida parapsilosis

Sophie Hartuis , Isabelle Ourliac-Garnier , Estelle Robert , Marjorie Albassier , Léa Duchesne et al.

Antimicrobial Agents and Chemotherapy, 2024, 68 (6), ⟨10.1128/aac.00022-24⟩

Article dans une revue hal-04879909v1

Antifungal efficacy of imidazo[1,2- a]pyrazine-based thiosemicarbazones and thiazolidinediones against Sporothrix species

Reginaldo Lima-Neto , Marlene Sa Neta , Carlos At Valeriano , Rejane Neves , Armando Lacerda et al.

Future Microbiology, 2023, 18 (17), pp.1225-1233. ⟨10.2217/fmb-2023-0044⟩

Article dans une revue hal-04809019v1
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Is the C-Terminal Domain an Effective and Selective Target for the Design of Hsp90 Inhibitors against Candida Yeast?

Célia Rouges , Mohammad Asad , Adèle D Laurent , Pascal Marchand , Patrice Le Pape

Microorganisms, 2023, 11 (12), pp.2837. ⟨10.3390/microorganisms11122837⟩

Article dans une revue hal-04805310v1
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The Mortality Attributable to Candidemia in C. auris Is Higher than That in Other Candida Species: Myth or Reality?

Carlos A Alvarez-Moreno , Soraya Morales-López , Gerson J Rodriguez , Jose Y Rodriguez , Estelle Robert et al.

Journal of Fungi, 2023, 9 (4), pp.430. ⟨10.3390/jof9040430⟩

Article dans une revue hal-04809127v1
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Acquired fluconazole resistance and genetic clustering in Diutina (Candida) catenulata from clinical samples

Céline Nourrisson , Maxime Moniot , Rose-Anne Lavergne , Estelle Robert , Virginie Bonnin et al.

Clinical Microbiology and Infection, 2023, 29 (2), pp.257.e7-257.e11. ⟨10.1016/j.cmi.2022.09.021⟩

Article dans une revue hal-04758751v1
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Discovery of New Broad-Spectrum Anti-Infectives for Eukaryotic Pathogens Using Bioorganometallic Chemistry

Yan Lin , Hyeim Jung , Christina Bulman , James Ng , Robin Vinck et al.

Journal of Medicinal Chemistry, 2023, 66 (23), ⟨10.1021/acs.jmedchem.3c01333⟩

Article dans une revue hal-04311470v1
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Impact of TR34/L98H, TR46/Y121F/T289A and TR53 Alterations in Azole-Resistant Aspergillus fumigatus on Sterol Composition and Modifications after In Vitro Exposure to Itraconazole and Voriconazole

Rose-Anne Lavergne , Marjorie Albassier , Jean-Benoît Hardouin , Carlos Alvarez-Moreno , Fabrice Pagniez et al.

Microorganisms, 2022, 10 (1), pp.104. ⟨10.3390/microorganisms10010104⟩

Article dans une revue hal-03778408v1
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Prototheca Infections and Ecology from a One Health Perspective

Balázs Libisch , Carine Picot , Andrés Ceballos-Garzon , Monika Moravkova , Marcela Klimesová et al.

Microorganisms, 2022, 10 (5), pp.938. ⟨10.3390/microorganisms10050938⟩

Article dans une revue (article de synthèse) hal-03825222v1

Lethal destructive sinusopathy due to amphotericin B-resistant Aspergillus flavus: A case report.

Tiago Luiz Lagedo Ferraz , Eduardo Marques De Araújo , Rodolfo Froes Calixto , Monique Lima Martins Sampaio , Luciana Rezende Bandeira de Mello et al.

Revista Iberoamericana de Micología, 2022, 39 (1), pp.21-24. ⟨10.1016/j.riam.2022.01.001⟩

Article dans une revue hal-04753932v1
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Highly Conserved gsc1 Gene of Pneumocystis jirovecii in Patients with or without Prior Exposure to Echinocandins

Pierre Bonnet , Solène Le Gal , Claire Hoffmann , Florent Morio , Fouleymata Diabira et al.

Antimicrobial Agents and Chemotherapy, 2022, 66 (1), ⟨10.1128/AAC.01563-21⟩

Article dans une revue hal-04301232v1

Otomycosis Caused by the Cryptic and Emerging Species Aspergillus sydowii : Two Case Reports

Maria Ds Buonafina-Paz , Franz Ag Santos , Melyna Leite-Andrade , Adryelle Is Alves , Jadson Dp Bezerra et al.

Future Microbiology, 2022, 17 (18), pp.1437-1443. ⟨10.2217/fmb-2022-0137⟩

Article dans une revue hal-04759034v1
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The Novodiag® Stool parasites assay, an innovative high-plex technique for fast detection of protozoa, helminths and microsporidia in stool samples: a retrospective and prospective study

Sophie Hartuis , Rose-Anne Lavergne , Céline Nourrisson , Jaco Verweij , Guillaume Desoubeaux et al.

Parasite, 2022, 29, pp.1-8. ⟨10.1051/parasite/2022026⟩

Article dans une revue hal-03668002v1
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Fungal infections in mechanically ventilated patients with COVID-19 during the first wave: the French multicentre MYCOVID study

Jean-Pierre Gangneux , Eric Dannaoui , Arnaud Fekkar , Charles-Edouard Luyt , Françoise Botterel et al.

The Lancet Respiratory Medicine, 2022, 10 (2), pp.180-190. ⟨10.1016/s2213-2600(21)00442-2⟩

Article dans une revue inserm-03587204v1

Contribution of the anaerobic blood culture vial for the recovery of Candida glabrata : A retrospective multicentric study

Eric Farfour , Cecile Le Brun , Assaf Mizrahi , Pauline Bargain , Marie-Fleur Durieux et al.

Medical Mycology, 2022, 60 (4), ⟨10.1093/mmy/myac021⟩

Article dans une revue hal-04316567v1

Head‐to‐head comparison of CLSI, EUCAST, Etest and VITEK®2 results for Candida auris susceptibility testing

Andrés Ceballos-Garzon , Guillermo Garcia-Effron , Susana Cordoba , Jose Rodriguez , Carlos Alvarez-Moreno et al.

International Journal of Antimicrobial Agents, 2022, 59 (4), pp.106558. ⟨10.1016/j.ijantimicag.2022.106558⟩

Article dans une revue hal-04753908v1
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CRISPR-Cas9 approach confirms Calcineurin-responsive zinc finger 1 (Crz1) transcription factor as a promising therapeutic target in echinocandin-resistant Candida glabrata

Andres Ceballos-Garzon , Elvira Roman , Jesús Pla , Fabrice Pagniez , Daniela Amado et al.

PLoS ONE, 2022, 17 (3), pp.e0265777. ⟨10.1371/journal.pone.0265777⟩

Article dans une revue hal-04753979v1
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Selecting a multiplex PCR panel for accurate molecular diagnosis of intestinal protists: a comparative study of Allplex ® (Seegene ® ), G-DiaParaTrio (Diagenode ® ), and RIDA ® GENE (R-Biopharm ® ) assays and microscopic examination

Nicolas Argy , Céline Nourrisson , Ahmed Aboubacar , Philippe Poirier , Stéphane Valot et al.

Parasite, 2022, 29, pp.5. ⟨10.1051/parasite/2022003⟩

Article dans une revue hal-03572136v1
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Active Surveillance Program to Increase Awareness on Invasive Fungal Diseases: the French RESSIF Network (2012 to 2018)

Stéphane Bretagne , Karine Sitbon , Marie Desnos-Ollivier , Dea Garcia-Hermoso , Valérie Letscher-Bru et al.

mBio, 2022, 13 (3), pp.e0092022. ⟨10.1128/mbio.00920-22⟩

Article dans une revue hal-03658122v1

Une expulsion bien singulière d'un ver adulte de Loa loa

Arthur Aubry , Charles Hervochon , Marie Chauveau , Marie Denis-Musquer , Fakhri Jeddi et al.

Revue Francophone des Laboratoires, 2022, 538, pp.72-75. ⟨10.1016/S1773-035X(21)00381-6⟩

Article dans une revue hal-03630278v1
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In vitro identification of imidazo[1,2-a]pyrazine-based antileishmanial agents and evaluation of L. major casein kinase 1 inhibition

Marc-Antoine Bazin , Sandrine Cojean , Fabrice Pagniez , Guillaume Bernadat , Christian Cavé et al.

European Journal of Medicinal Chemistry, 2021, 210, pp.112956. ⟨10.1016/j.ejmech.2020.112956⟩

Article dans une revue pasteur-03108849v1
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Characterisation of the antifungal effects of a plant-based compound, CIN-102, on the main septal filamentous fungi involved in human pathology

Maurine d'Agostino , Nicolas Tesse , Rose‐anne Lavergne , Patrice Le Pape , Jean Philippe Bouchara et al.

Journal of Global Antimicrobial Resistance, 2021, 25, pp.171-180. ⟨10.1016/j.jgar.2021.03.017⟩

Article dans une revue hal-03210125v1
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Hygienic Perspectives of Wood in Healthcare Buildings

Muhammad Tanveer Munir , Muhammad Tanveer Munir , Hélène Pailhoriès , Florence Aviat , Didier Lepelletier et al.

Mental hygiene, 2021, 1 (1), pp.12-23. ⟨10.3390/hygiene1010002⟩

Article dans une revue (article de synthèse) hal-03338877v1
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In vitro antifungal effect of a plant-based product, CIN-102, on antifungal resistant filamentous fungi and their biofilms

Maurine d'Agostino , Nicolas Tesse , Rose‐anne Lavergne , Patrice Le Pape , Jean Pol Frippiat et al.

Journal of Medical Microbiology, 2021, 70 (9), pp.768-773. ⟨10.1099/jmm.0.001399⟩

Article dans une revue hal-04482563v1

Collateral consequences of agricultural fungicides on pathogenic yeasts: A One Health perspective to tackle azole resistance

Débora Castelo‐branco , Shawn Lockhart , Yee‐chun Chen , Daniel Santos , Ferry Hagen et al.

Mycoses, 2021, 65, pp.303 - 311. ⟨10.1111/myc.13404⟩

Article dans une revue hal-03630279v1
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Genotypic, proteomic, and phenotypic approaches to decipher the response to caspofungin and calcineurin inhibitors in clinical isolates of echinocandin-resistant<i>Candida glabrata</i>

Andres Ceballos-Garzon , Lucia Monteoliva , Concha Gil , Carlos Alvarez-Moreno , Nelson E Vega-Vela et al.

Journal of Antimicrobial Chemotherapy, 2021, 77, pp.585 - 597. ⟨10.1093/jac/dkab454⟩

Article dans une revue hal-04725773v1
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Anti-protozoal and anti-fungal evaluation of 3,5-disubstituted 1,2-dioxolanes

Alexis Pinet , Sandrine Cojean , Linh Thuy Nguyen , Pedro Vásquez-Ocmín , Alexandre Maciuk et al.

Bioorganic and Medicinal Chemistry Letters, 2021, 47, pp.128196. ⟨10.1016/j.bmcl.2021.128196⟩

Article dans une revue hal-03320600v1
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Multicenter Evaluation of an ELISA for the Detection of Cryptosporidium spp. Antigen in Clinical Human Stool Samples

Romy Razakandrainibe , Célia Mérat , Nathalie Kapel , Marc Sautour , Karine Guyot et al.

Microorganisms, 2021, 9 (2), pp.209. ⟨10.3390/microorganisms9020209⟩

Article dans une revue hal-03152175v1
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Confocal spectral microscopy, a non-destructive approach to follow contamination and biofilm formation of mCherry Staphylococcus aureus on solid surfaces

Muhammad Tanveer Munir , Nattar Maneewan , Julien Pichon , Mohammed Gharbia , Ismael Oumarou-Mahamane et al.

Scientific Reports, 2021, 11 (1), pp.1-11. ⟨10.1038/s41598-021-94939-2⟩

Article dans une revue hal-03338868v1

Candida auris : A Latent Threat to Critically Ill Patients With Coronavirus Disease 2019

Jose Rodriguez , Patrice Le Pape , Olga Lopez , Kelin Esquea , Anny Labiosa et al.

Clinical Infectious Diseases, 2021, 73 (9), pp.e2836-e2837. ⟨10.1093/cid/ciaa1595⟩

Article dans une revue hal-04719737v1

The Extend of Aspergillosis in Critically Ill Patients With Severe Influenza Pneumonia: A Multicenter Cohort Study

Anne Coste , Aurélien Frérou , Anaïs Raute , Francis Couturaud , Jean Morin et al.

Critical Care Medicine, 2021, Publish Ahead of Print (6), ⟨10.1097/CCM.0000000000004861⟩

Article dans une revue hal-03229050v1
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Synthesis, Optimization, Antifungal Activity, Selectivity, and CYP51 Binding of New 2-Aryl-3-azolyl-1-indolyl-propan-2-ols

Nicolas Lebouvier , Fabrice Pagniez , Young Min Na , Da Shi , Patricia Pinson et al.

Pharmaceuticals, 2020, 13 (8), 186 (32 p.). ⟨10.3390/ph13080186⟩

Article dans une revue hal-02913479v2

Invasive aspergillosis due to Aspergillus section Usti: a multicenter retrospective study

Emmanouil Glampedakis , Sophie Cassaing , Arnaud Fekkar , Eric Dannaoui , Marie-Elisabeth Bougnoux et al.

Clinical Infectious Diseases, 2020, 72, pp.1379-1385. ⟨10.1093/cid/ciaa230⟩

Article dans une revue hal-02543503v1
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Biological exploration of a novel 1,2,4-triazole-indole hybrid molecule as antifungal agent

Fabrice Pagniez , Nicolas Lebouvier , Young Min Na , Isabelle Ourliac-Garnier , Carine Picot et al.

Journal of Enzyme Inhibition and Medicinal Chemistry, 2020, 35 (1), pp.398-403. ⟨10.1080/14756366.2019.1705292⟩

Article dans une revue hal-02455791v2
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New azole antifungals with a fused triazinone scaffold

David Montoir , Rémi Guillon , Sophie Gazzola , Isabelle Ourliac-Garnier , Kossi Efouako Soklou et al.

European Journal of Medicinal Chemistry, 2020, 189, pp.112082. ⟨10.1016/j.ejmech.2020.112082⟩

Article dans une revue hal-03412473v1
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Determination of antifungal caspofungin in RPMI-1640 cell culture medium by column-switching HPLC-FLD

B. Uribe , O. González , Isabelle Ourliac-Garnier , Patrice Le Pape , B.B. Ba et al.

Journal of Pharmaceutical and Biomedical Analysis, 2020, 188, pp.113366 -. ⟨10.1016/j.jpba.2020.113366⟩

Article dans une revue hal-03490720v1
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Survival of Bacterial Strains on Wood (Quercus petraea) Compared to Polycarbonate, Aluminum and Stainless Steel

Ju-Chi Chen , Muhammad Tanveer Munir , Florence Aviat , Didier Lepelletier , Patrice Le Pape et al.

Antibiotics, 2020, 9 (11), pp.1-9. ⟨10.3390/antibiotics9110804⟩

Article dans une revue hal-03133972v1

Impact of calmodulin inhibition by fluphenazine on susceptibility, biofilm formation and pathogenicity of caspofungin-resistant Candida glabrata

Andrés Ceballos-Garzón , Daniela Amado , Estelle Robert , Claudia Parra Giraldo , Patrice Le Pape

Journal of Antimicrobial Chemotherapy, 2020, 75 (5), pp.1187-1193. ⟨10.1093/jac/dkz565⟩

Article dans une revue hal-04719001v1
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Impact of fecal microbiota transplantation on chronic recurrent pouchitis in ulcerative colitis with ileo-anal anastomosis: study protocol for a prospective, multicenter, double-blind, randomized, controlled trial

Caroline Trang-Poisson , Elise Kerdreux , Alexandra Poinas , Lucie Planche , Harry Sokol et al.

Trials, 2020, 21 (1), ⟨10.1186/s13063-020-04330-1⟩

Article dans une revue hal-03379520v1

Pneumocystis Infection Outbreaks in Organ Transplantation Units in France: A Nation-Wide Survey

Solène Le Gal , Dominique Toubas , Anne Totet , Frédéric Dalle , Ahmed Abou Bacar et al.

Clinical Infectious Diseases, 2020, 70 (10), pp.2216-2220. ⟨10.1093/cid/ciz901⟩

Article dans une revue hal-02543278v1
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A One Health Perspective to Recognize Fusarium as Important in Clinical Practice

Valeri Sáenz , Carlos Alvarez-Moreno , Patrice Le Pape , Silvia Restrepo , Josep Guarro et al.

Journal of Fungi, 2020, 6 (4), pp.235. ⟨10.3390/jof6040235⟩

Article dans une revue hal-03808025v2
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In vitro immune responses of human PBMCs against Candida albicans reveals fungal and leucocyte phenotypes associated with fungal persistence

Nidia ALVAREZ RUEDA , Célia Rouges , Adel Touahri , Barbara Misme-Aucouturier , Marjorie Albassier et al.

Scientific Reports, 2020, 10 (1), ⟨10.1038/s41598-020-63344-6⟩

Article dans une revue hal-04125813v2

Palindromic Peptide LfcinB (21‐25) Pal Exhibited Antifungal Activity against Multidrug‐Resistant Candida

Yerly Vargas-Casanova , Jean Carlos Villamil Poveda , Zuly Jenny Rivera-Monroy , Andrés Ceballos-Garzón , Ricardo Fierro-Medina et al.

ChemistrySelect, 2020, 5 (24), pp.7236-7242. ⟨10.1002/slct.202001329⟩

Article dans une revue hal-04719734v1

Wood materials for limiting the bacterial reservoir on surfaces in hospitals: would it be worthwhile to go further?

Muhammad T munir , Florence Aviat , Didier Lepelletier , Patrice Le Pape , Laurence Dubreil et al.

Future Microbiology, 2020, 15 (15), pp.1431-1437. ⟨10.2217/fmb-2019-0339⟩

Article dans une revue hal-03133969v1
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Medicopsis romeroi nodular subcutaneous infection in a kidney transplant recipient

Fakhri Jeddi , Charlotte Paugam , Sophie Hartuis , Marie Denis-Musquer , Marcela Sabou et al.

International Journal of Infectious Diseases, 2020, 95, pp.262 - 264. ⟨10.1016/j.ijid.2020.04.028⟩

Article dans une revue hal-04719518v1

Mucorales DNA detection in serum specimens for early diagnosis of mucormycosis

Claire Hoffmann , Gaëlle Guillerm , Patrice Le Pape , Liana Carausu , Rose-Anne Lavergne et al.

Diagnostic Microbiology and Infectious Disease, 2020, 97 (2), pp.115004. ⟨10.1016/j.diagmicrobio.2020.115004⟩

Article dans une revue hal-02507424v1
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Ibrutinib, a Bruton's tyrosine kinase inhibitor, a new risk factor for cryptococcosis

Julia Brochard , Florent Morio , Julien Mahe , Patrice Le Pape , T. Guimard et al.

Médecine et Maladies Infectieuses (1971-2020), 2020, 50, pp.742 - 745. ⟨10.1016/j.medmal.2020.07.005⟩

Article dans une revue hal-03492593v1
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Persistence of clonal azole-resistant isolates of Candida albicans from a patient with chronic mucocutaneous candidiasis in Colombia

Andrés Ceballos-Garzón , Luz M Wintaco-Martínez , Norida Velez , Catalina Hernandez-Padilla , Alejandro De la Hoz et al.

Journal of Global Infectious Diseases, 2020, 12, pp.16-20. ⟨10.4103/jgid.jgid_74_19⟩

Article dans une revue hal-04719445v1
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Species Distribution and Comparison between EUCAST and Gradient Concentration Strips Methods for Antifungal Susceptibility Testing of 112 Aspergillus Section Nigri Isolates

B. Carrara , R. Richards , S. Imbert , Florent Morio , Milène Sasso et al.

Antimicrobial Agents and Chemotherapy, 2020, 64 (7), ⟨10.1128/AAC.02510-19⟩

Article dans une revue (data paper) hal-04850428v1
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Comparison of MultiLocus Sequence Typing (MLST) and Microsatellite Length Polymorphism (MLP) for Pneumocystis jirovecii genotyping

Maud Gits-Muselli , Pascal Campagne , Marie Desnos-Ollivier , Patrice Le Pape , Stéphane Bretagne et al.

Computational and Structural Biotechnology Journal, 2020, 18, pp.2890-2896. ⟨10.1016/j.csbj.2020.10.005⟩

Article dans une revue pasteur-03243552v1

Antimicrobial and antileishmanial activities of extracts and some constituents from the leaves of Solanum chrysotrichum Schldl

Guillermo Núñez-Mojica , Verónica Rivas-Galindo , Elvira Garza-González , Luis Miranda , Adriana Romo-Pérez et al.

Medicinal Chemistry Research, 2020, 30 (1), pp.152-162. ⟨10.1007/s00044-020-02648-8⟩

Article dans une revue hal-04721673v1

Assessment of the first commercial multiplex PCR kit (ParaGENIE Crypto-Micro Real-Time PCR) for the detection of Cryptosporidium spp., Enterocytozoon bieneusi, and Encephalitozoon intestinalis from fecal samples

Florent Morio , Philippe Poirier , Yohann Le Govic , Adrien Laude , Stephane Valot et al.

Diagnostic Microbiology and Infectious Disease, 2019, 95 (1), pp.34-37. ⟨10.1016/j.diagmicrobio.2019.04.004⟩

Article dans une revue istex hal-02483139v1
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Prevalence, geographic risk factor, and development of a standardized protocol for fungal isolation in cystic fibrosis: Results from the international prospective study “MFIP”

Laurence Delhaes , Kada Touati , Muriel Cornet , Rafael Cantón , Françoise Botterel et al.

Journal of Cystic Fibrosis, 2019, 18 (2), pp.212-220. ⟨10.1016/j.jcf.2018.10.001⟩

Article dans une revue hal-02316590v1

Candida auris : faut-il redouter l'émergence d'un champignon hautement résistant ?

Patrice Le Pape , Carlos Alvarez-Moreno

La Lettre de l'Infectiologue, 2019, 36, pp.234-235

Article dans une revue hal-04718771v1

Fungicide-driven alterations in azole-resistant Aspergillus fumigatus are related to vegetable crops in Colombia, South America

Carlos Alvarez-Moreno , Rose-Anne Lavergne , Ferry Hagen , Florent Morio , Jacques Meis et al.

Mycologia, 2019, 111 (2), pp.217-224. ⟨10.1080/00275514.2018.1557796⟩

Article dans une revue hal-04712281v1

Disseminated mucormycosis due to Lichtheimia corymbifera during ibrutinib treatment for relapsed chronic lymphocytic leukaemia: a case report

Olivier Grossi , Samuel Pineau , Sophie Sadot-Lebouvier , B. Hay , J. Delaunay et al.

Clinical Microbiology and Infection, 2019, 25 (2), pp.261-263. ⟨10.1016/j.cmi.2018.10.004⟩

Article dans une revue hal-04712256v1
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First case of Aspergillus caelatus airway colonization in a Chronic Obstructive Pulmonary Disease patient

Patrice Le Pape , Rafael Matos Ximenes , Beatriz Ariza , Juan Iriarte , Jaime Alvarado et al.

International Journal of Infectious Diseases, 2019, 81, pp. 85-90. ⟨10.1016/j.ijid.2019.01.043⟩

Article dans une revue hal-03823684v1

Rapid diagnostic tests relying on antigen detection from stool as an efficient point of care testing strategy for giardiasis and cryptosporidiosis? Evaluation of a new immunochromatographic duplex assay

Adeline Goudal , Adrien Laude , Stéphane Valot , Guillaume Desoubeaux , Nicolas Argy et al.

Diagnostic Microbiology and Infectious Disease, 2019, 93 (1), pp.33-36. ⟨10.1016/j.diagmicrobio.2018.07.012⟩

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Pharmaceuticals, 2019, 12, ⟨10.3390/ph12040182⟩

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Double positive CD4+CD8+ T cells are part of the adaptive immune response against Candida albicans

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Human Immunology, 2019, 80, pp.999 - 1005. ⟨10.1016/j.humimm.2019.09.008⟩

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Brain abscess to Rasamsonia argillacea in a patient with chronic granulomatous disease

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Comparison between MALDI-TOF MS and MicroScan in the identification of emerging and multidrug resistant yeasts in a fourth-level hospital in Bogotá, Colombia

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BMC Microbiology, 2019, 19 (1), pp.106. ⟨10.1186/s12866-019-1482-y⟩

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Florent Morio , Lisa Lombardi , Ulrike Binder , Cédric Logé , Estelle Robert et al.

Journal of Antimicrobial Chemotherapy, 2019, 74 (8), pp.2230-2238. ⟨10.1093/jac/dkz204⟩

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PCR-based detection of Aspergillus fumigatus and absence of azole resistance due to TR 34 /L98H in a french multicenter cohort of 137 patients with fungal rhinosinusitis

Florent Morio , Eric Dannaoui , Taieb Chouaki , Estelle Cateau , Olivier Malard et al.

Mycoses, 2018, 61 (1), pp.30 - 34. ⟨10.1111/myc.12702⟩

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Bioorganic and Medicinal Chemistry, 2018, 28 (13), pp.2250-2255. ⟨10.1016/j.bmcl.2018.05.044⟩

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Chemistry - A European Journal, 2018, 24 (72), pp.19243-19249. ⟨10.1002/chem.201803602⟩

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Clinical Microbiology and Infection, 2018, 24 (11), pp.1205-1209. ⟨10.1016/j.cmi.2018.02.007⟩

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First report of sporadic cases of Candida auris in Colombia

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International Journal of Infectious Diseases, 2018, 69, pp.63-67. ⟨10.1016/j.ijid.2018.01.034⟩

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Azole Resistance in Aspergillus fumigatus in Patients with Cystic Fibrosis: A Matter of Concern?

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Mycopathologia, 2018, 183 (1), pp.151-160. ⟨10.1007/s11046-017-0162-4⟩

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Gene flow contributes to diversification of the major fungal pathogen $Candida\ albicans$

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Nature Communications, 2018, 9 (1), pp.2253. ⟨10.1038/s41467-018-04787-4⟩

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Molecular basis of antifungal drug resistance in yeasts

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Emergence of Aspergillus fumigatus azole resistance in azole-naïve patients with chronic obstructive pulmonary disease and their homes

C. Dauchy , N. Bautin , S. Nseir , G. Reboux , R. Wintjens et al.

Indoor Air, 2017, 28, pp.298-306. ⟨10.1111/ina.12436⟩

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Home Environment as a Source of Life-Threatening Azole-Resistant Aspergillus fumigatus in Immunocompromised Patients

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Clinical Infectious Diseases, 2017, 64 (1), pp.76-78. ⟨10.1093/cid/ciw664⟩

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Specific Human and Candida Cellular Interactions Lead to Controlled or Persistent Infection Outcomes during Granuloma-Like Formation

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Is real-time PCR-based diagnosis similar in performance to routine parasitological examination for the identification of Giardia intestinalis , Cryptosporidium parvum / Cryptosporidium hominis and Entamoeba histolytica from stool samples? Evaluation of a new commercial multiplex PCR assay and literature review

A. Laude , S. Valot , Guillaume Desoubeaux , N. Argy , C. Nourrisson et al.

Clinical Microbiology and Infection, 2016, 22 (2), pp.190.e1-190.e8. ⟨10.1016/j.cmi.2015.10.019⟩

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Diagnostic Microbiology and Infectious Disease, 2016, 86 (4), pp.385 - 386. ⟨10.1016/j.diagmicrobio.2016.08.028⟩

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Epidemiology, risk factor, species distribution, antifungal resistance and outcome of Candidemia at a single French hospital: a 7-year study

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Mycoses, 2016, 59 (5), pp.296-303. ⟨10.1111/myc.12470⟩

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Econazole imprinted textiles with antifungal activity

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European Journal of Pharmaceutics and Biopharmaceutics, 2016, ⟨10.1016/j.ejpb.2016.02.003⟩

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Saksenaea erythrospora infection after medical tourism for esthetic breast augmentation surgery

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International Journal of Infectious Diseases, 2016, 49, pp.107-110. ⟨10.1016/j.ijid.2016.05.032⟩

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Answer to May 2016 Photo Quiz

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First Description of Azole-Resistant Aspergillus fumigatus Due to TR 46 /Y121F/T289A Mutation in France

Rose-Anne Lavergne , Florent Morio , Loïc Favennec , Stéphane Dominique , Jacques Meis et al.

Antimicrobial Agents and Chemotherapy, 2015, 59 (7), pp.4331-4335. ⟨10.1128/AAC.00127-15⟩

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Is procalcitonin increased in cases of invasive amoebiasis? A retrospective, observational study

Guillaume Recipon , Eric Piver , Agnès Caille , Patrice Le Pape , Marc Pihet et al.

Diagnostic Microbiology and Infectious Disease, 2015, 83 (4), pp.395-399. ⟨10.1016/j.diagmicrobio.2015.08.014⟩

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Synthesis, antileishmanial activity and cytotoxicity of 2,3-diaryl- and 2,3,8-trisubstituted imidazo[1,2-a]pyrazines

Pascal Marchand , Marc-Antoine Bazin , Fabrice Pagniez , Guillaume Rivière , Lizeth Bodero et al.

European Journal of Medicinal Chemistry, 2015, 103, pp.381-395. ⟨10.1016/j.ejmech.2015.09.002⟩

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European Journal of Medicinal Chemistry, 2014, 81, pp.378-393. ⟨10.1016/j.ejmech.2014.05.037⟩

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Discovery of a Novel Broad-Spectrum Antifungal Agent Derived from Albaconazole

Rémi Guillon , Fabrice Pagniez , Carine Picot , Damien Hédou , Alain Tonnerre et al.

ACS Medicinal Chemistry Letters, 2013, 4 (2), pp.288-292. ⟨10.1021/ml300429p⟩

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Anti-AGEs and antiparasitic activity of an original prenylated isoflavonoid and flavanones isolated from Derris ferruginea

Sylvie Morel , Jean-Jacques Helesbeux , Denis Séraphin , Séverine Derbré , Julia Gatto et al.

Phytochemistry Letters, 2013, 6 (3), pp.498-503. ⟨10.1016/j.phytol.2013.06.002⟩

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Deciphering azole resistance mechanisms with a focus on transcription factor-encoding genes TAC1, MRR1 and UPC2 in a set of fluconazole-resistant clinical isolates of Candida albicans

Florent Morio , Fabrice Pagniez , Myriam Besse , Françoise Gay-Andrieu , Michel Miegeville et al.

International Journal of Antimicrobial Agents, 2013, 42 (5), pp.410-415. ⟨10.1016/j.ijantimicag.2013.07.013⟩

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Anti-AGEs and antiparasitic activity of an original prenylated isoflavonoid and flavanones isolated from Derris ferruginea

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Phytochemistry Letters, 2013, 6 (3), pp.498-503. ⟨10.1016/j.phytol.2013.06.002⟩

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Multiplexed infectious protein microarray immunoassay suitable for the study of the specificity of monoclonal immunoglobulins

Delphine Feron , Cathy Charlier , Victor Gourain , Laurent Garderet , Marianne Coste-Burel et al.

Analytical Biochemistry, 2013, 433, pp.202 - 209. ⟨10.1016/j.ab.2012.10.012⟩

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High prevalence of triazole resistance in Aspergillus fumigatus, especially mediated by TR/L98H, in a French cohort of patients with cystic fibrosis

Florent Morio , Guillaume Ghislain Aubin , Isabelle Danner-Boucher , Alain Haloun , Emilie Sacchetto et al.

Journal of Antimicrobial Chemotherapy, 2012, 67 (8), pp.1870-1873. ⟨10.1093/jac/dks160⟩

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Synthesis and biological evaluation of 2,3-diarylimidazo[1,2-a]pyridines as antileishmanial agents

Sophie Marhadour , Pascal Marchand , Fabrice Pagniez , Marc-Antoine Bazin , Carine Picot et al.

European Journal of Medicinal Chemistry, 2012, 58, pp.543-556. ⟨10.1016/j.ejmech.2012.10.048⟩

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Preparative Isolation, Fast Centrifugal Partition Chromatography Purification and Biological Activity of Cajaflavanone from Derris ferruginea Stems

Sylvie Morel , Anne Landreau , van Hung Nguyen , Séverine Derbré , Philippe Grellier et al.

Phytochemical Analysis, 2012, 23 (2), pp.152-158. ⟨10.1002/pca.1336⟩

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Amino acid substitutions in the Candida albicans sterol 5,6-desaturase (Erg3p) confer azole resistance: characterization of two novel mutants with impaired virulence

Florent Morio , Fabrice Pagniez , C. Lacroix , Michel Miegeville , Patrice Le Pape

Journal of Antimicrobial Chemotherapy, 2012, 67 (9), pp.2131-2138. ⟨10.1093/jac/dks186⟩

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Design, Synthesis, and in vitro Antifungal Activity of 1-[(4-Substituted-benzyl)methylamino]-2-(2,4-difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ols

Rémi Guillon , Fabrice Pagniez , Francis Giraud , Damien Crépin , Carine Picot et al.

ChemMedChem, 2011, 6 (5), pp.816 - 825. ⟨10.1002/cmdc.201000530⟩

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Fatal Invasive Infection with Fungemia Due to Microascus cirrosus after Heart and Lung Transplantation in a Patient with Cystic Fibrosis

Charline Miossec , Florent Morio , Thierry Lepoivre , Patrice Le Pape , Dea Garcia-Hermoso et al.

Journal of Clinical Microbiology, 2011, 49 (7), pp.2743-2747. ⟨10.1128/JCM.00127-11⟩

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A novel large regulator RNA, B2, partially overlaps the HEF1/NEDD9/Cas-L gene

Marine Malleter , Catherine Jacquot , Dimitri Moreau , Christophe Tomasoni , Ioanna Chinou et al.

International Journal of Molecular Medicine, 2010, 25 (6), pp.897-903. ⟨10.3892/ijmm_00000420⟩

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Isoquinolines from the Roots of Thalictrum flavum L. and Their Evaluation as Antiparasitic Compounds

Jacqueline Ropivia , Séverine Derbré , Caroline Rouger , Fabrice Pagniez , Patrice Le Pape et al.

Molecules, 2010, 15 (9), pp.6476-6484. ⟨10.3390/molecules15096476⟩

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Synthesis and in vitro antifungal evaluation of 2-(2,4-difluorophenyl)-1-[(1 H -indol-3-ylmethyl)methylamino]-3-(1 H -1,2,4-triazol-1-yl)propan-2-ols

Rémi Guillon , Cédric Logé , Fabrice Pagniez , Véronique Ferchaud-Roucher , Muriel Duflos et al.

Journal of Enzyme Inhibition and Medicinal Chemistry, 2010, 26 (2), pp.261-269. ⟨10.3109/14756366.2010.503607⟩

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Disseminated Scedosporium/Pseudallescheria Infection after Double-Lung Transplantation in Patients with Cystic Fibrosis

Florent Morio , Delphine Horeau-Langlard , Françoise Gay-Andrieu , Jean-Philippe Talarmin , Alain Haloun et al.

Journal of Clinical Microbiology, 2010, 48 (5), pp.1978 - 1982. ⟨10.1128/JCM.01840-09⟩

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Screening for amino acid substitutions in the Candida albicans Erg11 protein of azole-susceptible and azole-resistant clinical isolates: new substitutions and a review of the literature

Florent Morio , Cédric Logé , Bernard Besse , Christophe Hennequin , Patrice Le Pape

Diagnostic Microbiology and Infectious Disease, 2010, 66 (4), pp.373-384. ⟨10.1016/j.diagmicrobio.2009.11.006⟩

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Design of new antifungal agents: synthesis and evaluation of 1-[(1H-indol-5-ylmethyl)amino]-2-phenyl-3-(1H-1,2,4-triazol-1-yl)propan-2-ols

Rémi Guillon , Francis Giraud , Cédric Logé , Marc Le Borgne , Carine Picot et al.

Bioorganic and Medicinal Chemistry Letters, 2009, 19 (20), pp.5833 - 5836. ⟨10.1016/j.bmcl.2009.08.089⟩

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Synthesis and structure–activity relationships of 2-phenyl-1-[(pyridinyl- and piperidinylmethyl)amino]-3-(1H-1,2,4-triazol-1-yl)propan-2-ols as antifungal agents

Francis Giraud , Rémi Guillon , Cédric Logé , Fabrice Pagniez , Carine Picot et al.

Bioorganic and Medicinal Chemistry Letters, 2009, 19 (2), pp.301 - 304. ⟨10.1016/j.bmcl.2008.11.101⟩

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Design, synthesis and evaluation of 3-(imidazol- 1-ylmethyl)indoles as antileishmanial agents. Part II

Francis Giraud , Cédric Logé , Fabrice Pagniez , Damien Crépin , Sophie Barres et al.

Journal of Enzyme Inhibition and Medicinal Chemistry, 2009, 24 (5), pp.1067 - 1075. ⟨10.1080/14756360802610795⟩

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Design, synthesis, and evaluation of 1-(N-benzylamino)-2-phenyl-3-(1H-1,2,4-triazol-1-yl)propan-2-ols as antifungal agents

Francis Giraud , Cédric Logé , Fabrice Pagniez , Damien Crépin , Patrice Le Pape et al.

Bioorganic and Medicinal Chemistry Letters, 2008, 18 (6), pp.1820 - 1824. ⟨10.1016/j.bmcl.2008.02.027⟩

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Antileishmanial polyphenols from Garcinia vieillardii.

Anne-Emmanuelle Hay , Joumaa Merza , Anne Landreau , Marc Litaudon , Fabrice Pagniez et al.

Fitoterapia, 2008, 79 (1), pp.42-46. ⟨10.1016/j.fitote.2007.07.005⟩

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Synthesis and antifungal activities of new fluconazole analogues with azaheterocycle moiety

Nicolas Lebouvier , Fabrice Pagniez , Muriel Duflos , Patrice Le Pape , Young Min Na et al.

Bioorganic and Medicinal Chemistry Letters, 2007, 17 (13), pp.3686 - 3689. ⟨10.1016/j.bmcl.2007.04.038⟩

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Antileishmanial activities and mechanisms of action of indole-based azoles

Fabrice Pagniez , Hiam Abdala-Valencia , Pascal Marchand , Marc Le Borgne , Guillaume Le Baut et al.

Journal of Enzyme Inhibition and Medicinal Chemistry, 2006, 21 (3), pp.277 - 283. ⟨10.1080/14756360600700517⟩

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A 3D-QSAR CoMSIA study on 3-azolylmethylindoles as anti-leishmanial agents

Francis Giraud , Cédric Logé , Marc Le Borgne , Fabrice Pagniez , Young Min Na et al.

SAR and QSAR in Environmental Research, 2006, 17 (3), pp.299 - 309. ⟨10.1080/10659360600787494⟩

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Synthesis and Antileishmanial Activity of 3-Imidazolylalkylindoles. Part I

Young Min Na , Nicolas Lebouvier , Marc Le Borgne , Fabrice Pagniez , Nidia Alvarez et al.

Journal of Enzyme Inhibition and Medicinal Chemistry, 2004, 19 (6), pp.451 - 457. ⟨10.1080/14756360412331280509⟩

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Synthesis and antileishmanial activity of new imidazolidin-2-one derivatives

Jean-Michel Robert , Caroline Sabourin , Nidia Alvarez , Sylvie Robert-Piessard , Guillaume Le Baut et al.

European Journal of Medicinal Chemistry, 2003, 38 (7-8), pp.711-718. ⟨10.1016/s0223-5234(03)00119-3⟩

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Synthesis and antifungal activity of new 1-halogenobenzyl-3-imidazolylmethylindole derivatives

Young Min Na , Marc Le Borgne , Fabrice Pagniez , Guillaume Le Baut , Patrice Le Pape

European Journal of Medicinal Chemistry, 2003, 38 (1), pp.75 - 87. ⟨10.1016/S0223-5234(02)00005-3⟩

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Synthesis and Antileishmanial Activity of 3-(α-Azolylbenzyl)indoles

Pascal Marchand , Marc Le Borgne , Young Min Na , Fabrice Pagniez , Hiam Abdala et al.

Journal of Enzyme Inhibition and Medicinal Chemistry, 2002, 17 (6), pp.353 - 358. ⟨10.1080/1475636021000005613⟩

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In Vitro Activity of a New Antifungal Azolyl-substituted Indole Against Aspergillus fumigatus

Fabrice Pagniez , Marc Le Borgne , Pascal Marchand , Young Min Na , Guillaume Le Baut et al.

Journal of Enzyme Inhibition and Medicinal Chemistry, 2002, 17 (6), pp.425 - 429. ⟨10.1080/1475636021000005686⟩

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Potential application of plant lipid transfer proteins for drug delivery

Christine Pato , Marc Le Borgne , Guillaume Le Baut , Patrice Le Pape , Didier Marion et al.

Biochemical Pharmacology, 2001, 62 (5), pp.555 - 560. ⟨10.1016/S0006-2952(01)00708-0⟩

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