Access content directly

Philippe Lesot

150
Documents
Researcher identifiers

Presentation

### [**CNRS Director of research (DR-1 / INC, S-12)** ](../desktop) [(Research PI) "NMR methodologies and anisotropic deuterium NMR applications"](../desktop) #### *ORCID ID: 0000-0002-5811-7530 Researcher ID: M-3390-2017 Publons ID: Philippe Lesot* #### **RMN en Milieu Orienté, ICMMO, UMR-CNRS 8182, Bât. 410 Université Paris-Saclay 91405 Orsay cedex, Fra**nce **CONTACT &amp; WEBSITES :** Tél : ++ 33 (0)1 69 15 47 59 / 70 17 // Fax. : ++ 33 (0)1 69 15 81 05 E-mail: <philippe.lesot@u-psud.fr> ### [https://www.icmmo.u-psud.fr/fr/perso/philippe-lesot/ ](https://www.icmmo.u-psud.fr/fr/perso/philippe-lesot/)[https://www.researchgate.net/profile/Philippe\_Lesot ](https://www.researchgate.net/profile/Philippe_Lesot)<https://twitter.com/LesotPhilippe> ### [ ](https://twitter.com/LesotPhilippe)https://www.linkedin.com/in/philippe-lesot-47699b51/ **SHORT CV :** Dr. Philippe Lesot, born in October 1967, has been Research Director since 2007 at Institut de Chimie Moléculaire et des Materiaux d’Orsay (ICMMO) (France) located at Orsay (University of Paris-Sud/Paris-Saclay). He is affiliated to the french National Center for Scientific Research (CNRS since 1997. He received his Ph.D degree (cum laudae) at University of Paris-Sud (Orsay) in 1995 (supervisor: Prof. J. Courtieu), and then pursued his NMR research activities at University of Southampton (UK) with Prof. J.W. Emsley, awarded by both a grant from the Royal Society of London and the French Foreign Ministry (Lavoisier). After holding a temporary assistant professor position at Orsay for one year, he joined the CNRS in 1997. He was a recipient of the 2001 Bronze Medal from CNRS for young scientists for his pioneering work on the Natural abundance 2D-NMR spectroscopy in chiral liquid crystals. He has published over 110 publications in international, peer-review journals, 10 bbok chapters inclused two encyclopedian and given approx. 55 invited talks on the analytical and methodological developments in anisotropic NMR in collaboration with numerous (bio)chemists. His current research interests focus on the natural isotope fractionation of bioproducts by anisotropic NAD NMR and the fight against counterfeiting. **SCIENTIFIC MANAGEMENT ACTIVITY :** **\* Scientific board of the INC (CNRS)(2019-2022)** ``` <a href="http://www.cnrs.fr/comitenational/csi/csi_acc.htm">http://www.cnrs.fr/comitenational/csi/csi_acc.htm</a> <br></br><br></br> ``` #### Currently #### \* University office of Paris-Saclay (2020-2023) #### \* Board of the Academic Council of the Univeristy Paris-Saclay (2020-2023) #### \* Member of the CCSU ( 31-32-33) #### Previously : #### \* Board of the Academic Council of the COMUE Paris-Saclay (2015-2019) **\* Member of S-12 du CoNRS (2008-2012 / 2012-2016)** **\* Member of Chemistry Department COMUE Paris-Saclay (2015-2019)** **SCIENTIFIC EDITORIAL ACTIVITY :** **\* Associated Editors of Magnetic Resonance (MR) (2020-)** [https://www.magnetic-resonance-ampere.net/editorial\_board.html](http://www.magnetic-resonance-ampere.net/editorial_board.html) **\* Academic Editors of Concept in Magnetic Resonance A (2018-)** [\* https://www.hindawi.com/journals/cmra/editors/](https://www.hindawi.com/journals/cmra/editors/) ****\*** Member of editorial borad of "Spectra Analyse" PCI presse, (2014-2018)** **\* Board of the "Société Française des IsotopeS**" (SFIS) <https://www.sfis.eu> **\* Member of the India National Magnetic Resonance Society** (NMRS) [http://nmrs.iisc.ernet.in ](http://nmrs.iisc.ernet.in) #### **EXPERTISE COMMITMENT :** \* Expert for the French MESRI (BAP B) \* Expert for the «DFG» (Deutsche ForschungsGemeinschaft /Allemagne) \* Expert for the «Volskwagen Freigeist fellowships» (<http://www.volkswagenstiftung.de>) \* Expert «European Science Fundation » (<http://www..esf.org>) \* Expert «HCERES / AERES» \* Expert «ANR» \* Expert «Agences régionales» \* Chairman and expert of selection committees (ITRF, ITA, Assistant reader, **PREVIOUSLY :** \- DR1 at CNRS (2020-) \- DR2 at CNRS (2007-2019) \- CR1 at CNRS (1997 -2007) \- CR2 at CNRS (1997 -2000) \- Assistant lecturer (Univ Paris-Sud) (1996 -1997) \- Post-Doctoral researcher (University of Southamptopn, UK) (1995-1996) \- Thesis (1992-1995) **DISTINCTIONS :** \* Bronze medal of CNRS (2001) \* Royal Society of London fellowship (1995-1996) \* Lavoisier Grant (1995-1996) **SCIENTIFIC PRODUCTIONS :** \* Scientific book chapters : 8 \* Other book chapters : 2 \* Peer-reviewed articles : 114 \* Miscellaneous (large audience) articles: 13 \* Journal covers : 13 \* Cover profiles : 2 \* Invited talks: : 33 \* Seminars : 22 \* Oral communications : 67 \* Posters : 56 **CONFERENCE/WORKSHOP ORGANISATIONS :** \* "Thematic GBP NMR network" conference, France, Paris (2021) \* "GBP NMR network" Workshop, France, Orsay (2020) \* "7th Congress of SFIS, France (2019) \* "1st JFPSA", Marocco, Marrakesh, (2017) \* "Thematic GBP NMR network" conference ,France, Paris (2014) \* "GBP NMR network" Workshop, France, Orsay (2014)
Philippe Lesot, né en 1967, est directeur de recherche depuis 2007 à l'Institut de Chimie Moléculaire et des Matériaux d'Orsay (ICMMO) (France). Il est affilié au Centre National de la Recherche Scientifique (CNRS). Il a obtenu son doctorat (cum laudae) à l'Université de Paris-Sud (Orsay) en 1995 (superviseur : Prof. J. Courtieu), puis a poursuivi ses activités de recherche à l'Université de Southampton (UK) avec J.W. Emsley, grâce à une bourse de la Royal Society of London et du Ministère français des Affaires étrangères (Lavoisier). Après avoir occupé un poste de professeur assistant temporaire pendant un an, il a rejoint le CNRS en 1997. Il a reçu la Médaille de bronze 2001 du CNRS pour les jeunes scientifiques pour son travail de pionnier sur la RMN du NAD dans la CVX. Il a publié plus de 110 articles dans des revues internationales à comité de lecture, et a donné environ 55 conférences invitées sur les développements analytiques et méthodologiques de la RMN anisotrope en collaboration avec de nombreux (bio)chimistes. Ses intérêts de recherche actuels portent sur le fractionnement des isotopes naturels des bioproduits par RMN anisotrope NAD et la lutte contre la contrefaçon. Traduit avec www.DeepL.com/Translator

Publications

Image document

Spatially Resolved Anisotropic Natural Abundance Deuterium 2D-NMR Spectroscopy Using Bimesophasic Lyotropic Chiral Systems

Thomas Julien , Boris Gouilleux , Bernard Rousseau , Stefan Immel , Michael Reggelin
Journal of Physical Chemistry Letters, 2024, 15 (7), pp.2089-2095. ⟨10.1021/acs.jpclett.3c03302⟩
Journal articles hal-04471708v1
Image document

Potential and Performance of Anisotropic 19F NMR for the Enantiomeric Analysis of Fluorinated Chiral Active Pharmaceutical Ingredients

Boris Gouilleux , François-Marie Moussallieh , Philippe Lesot
Analyst, inPress, ⟨10.1039/d4an00237g⟩
Journal articles hal-04558310v1
Image document

Anisotropic 1H STD‐NMR Spectroscopy: Exploration of Enantiomer‐Polypeptide Interactions in Chiral Oriented Environments

Boris Gouilleux , Francois-Marie Moussallieh , Philippe Lesot
ChemPhysChem, 2022, 24 (4), pp.e202200508. ⟨10.1002/cphc.202200508⟩
Journal articles hal-03800520v1
Image document

Molecular enantiodiscrimination by NMR spectroscopy in chiral oriented systems: Concept, tools, and applications

Christie Aroulanda , Philippe Lesot
Chirality, 2022, 34, pp.182-244. ⟨10.1002/chir.23386⟩
Journal articles hal-03512385v1
Image document

Study and quantification of enantiodiscrimination power of four polymeric chiral LLCs using NAD 2D-NMR

Philippe Berdagué , Boris Gouilleux , Markus Noll , Stefan Immel , Michael Reggelin
Physical Chemistry Chemical Physics, 2022, 24 (12), pp.7338-7348. ⟨10.1039/D1CP04915A⟩
Journal articles hal-03586878v1
Image document

Exploring the enantiomeric 13C position-specific isotope fractionation: challenges and anisotropic NMR-based analytical strategy

Philippe Lesot , Philippe Berdagué , Virginie Silvestre , Gérald Remaud
Analytical and Bioanalytical Chemistry, 2021, 413 (25), pp.6379-6392. ⟨10.1007/s00216-021-03599-8⟩
Journal articles hal-03409628v1
Image document

Deuterium Residual Quadrupolar Couplings: Crossing the Current Frontiers in the Relative Configuration Analysis of Natural Products

Philippe Lesot , Roberto R. Gil , Philippe Berdague , Armando Navarro-Vázquez
Journal of Natural Products, 2020, 83 (10), pp.3141-3148. ⟨10.1021/acs.jnatprod.0c00745⟩
Journal articles hal-02949550v1
Image document

Determination of the natural deuterium distribution of fatty acids by application of 2H 2D-NMR in liquid crystals: fundamentals, advances, around and beyond

Philippe Lesot
Liquid Crystals, 2020, 47 (13), pp.1889-1910. ⟨10.1080/02678292.2019.1613685⟩
Journal articles hal-02308723v1
Image document

2H QUOSY 2D-NMR Experiments in Weakly Aligning Systems: From the Conventional to the UF Approach

Boris Gouilleux , Abdelkrim Meddour , Philippe Lesot
ChemPhysChem, 2020, 21, pp.1548-1563. ⟨10.1002/cphc.202000336⟩
Journal articles hal-02623845v1
Image document

Chemical Synthesis of [ 2 H]-Ethyl Tosylate and Exploration of Its Crypto-optically Active Character Combining Complementary Spectroscopic Tools

Timothée Naret , Philippe Lesot , Andrew Puente , Prasad Polavarapu , David-Alexandre Buisson
Organic Letters, 2020, 22 (22), pp.8846-8849. ⟨10.1021/acs.orglett.0c03219⟩
Journal articles hal-02987518v2
Image document

Hydrogen isotope exchange catalyzed by Ru nanocatalysts: labelling of complex molecules containing N-heterocycles and reaction mechanism insights

Viktor Pfeifer , Marie Certiat , Donia Bouzouita , Alberto Palazzolo , Sébastien Garcia-Argote
Chemistry - A European Journal, 2020, 26, pp.4988-4996. ⟨10.1002/chem.201905651⟩
Journal articles cea-02487414v1
Image document

Tuning the Reactivity of a Heterogeneous Catalyst using N‐Heterocyclic Carbene Ligands for C−H Activation Reactions

Alberto Palazzolo , Timothée Naret , Marion Daniel‐bertrand , David‐alexandre Buisson , Simon Tricard
Angewandte Chemie International Edition, 2020, 59 (47), pp.20879-20884. ⟨10.1002/anie.202009258⟩
Journal articles hal-03001484v1
Image document

2H and 13C NMR-Based Enantiodetection Using Polyacetylene versus Polypeptide Aligning Media: Versatile and Complementary Tools for Chemists

Philippe Lesot , Philippe Berdagué , Abdelkrim Meddour , Alexander Kreiter , Markus Noll
ChemPlusChem, 2019, 84 (2), pp.144-153. ⟨10.1002/cplu.201800493⟩
Journal articles hal-02308749v1
Image document

Designing and building a low-cost portable FT-NMR spectrometer in 2019: A modern challenge

Alain Louis-Joseph , Philippe Lesot
Comptes Rendus. Chimie, 2019, 22, pp.695-711. ⟨10.1016/j.crci.2019.07.001⟩
Journal articles hal-02308789v1

(Cover Profile) 2H and 13C NMR-Based Enantiodetection Using Polyacetylene versus Polypeptide Aligning Media: Versatile and Complementary Tools for Chemists

Philippe Lesot , Philippe Berdagué , Abdelkrim Meddour , Alexander Kreiter , Markus Noll
ChemPlusChem, 2019, pp.143-143. ⟨10.1002/cplu.201800584⟩
Journal articles hal-02308742v1
Image document

Multinuclear NMR in Polypeptide Liquid Crystals: Three Fertile Decades of Methodological Developments and Analytical Challenges

Philippe Lesot , Christie Aroulanda , Philippe Berdagué , Abdelkrim Meddour , Denis Merlet
Progress in Nuclear Magnetic Resonance Spectroscopy, 2019, Progress in Nuclear Magnetic Resonance Spectroscopy, 116, pp.85-154. ⟨10.1016/j.pnmrs.2019.10.001⟩
Journal articles hal-02351278v1

À MRFood 2018, les sciences slimentaires rencontrent la spectroscopie par résonance magnétique!

Philippe Lesot
Spectra Analyse, 2018, 323, pp.18-20
Journal articles hal-02317627v1

Analytical contribution of deuterium 2D-NMR in oriented media to H-2/H-1 isotopic characterization: the case of vanillin

Tristan Texier-Bonniot , Philippe Berdague , Richard J. Robins , Gérald Remaud , Philippe Lesot
Flavour and Fragrance Journal, 2018, 33 (3), pp.217-229. ⟨10.1002/ffj.3441⟩
Journal articles hal-02140951v1

Ruthenium-catalyzed hydrogen isotope exchange of C(sp3)–H bonds directed by a sulfur atom

Longhui Gao , Serge Perato , Sébastien Garcia-Argote , Céline Taglang , Luis Miguel Martinez-Pietro
Chemical Communications, 2018, 54 (24), pp.2986-2989. ⟨10.1039/C8CC00653A⟩
Journal articles hal-02308831v1

La “39th FGMR Annual Discussion Meeting 2017”: La Spectroscopie Magnétique Franco-Allemande dans tous ses “Etats”!

Philippe Lesot
Spectra Analyse, 2017, pp.12-14
Journal articles hal-02317591v1

Integrated Computational Protocol for the Analysis of Quadrupolar Splittings from Natural-Abundance Deuterium NMR Spectra in (Chiral) Oriented Media

Armando Navarro-Vázquez , Philippe Berdagué , Philippe Lesot
ChemPhysChem, 2017, 18 (10), pp.1252-1266. ⟨10.1002/cphc.201601423⟩
Journal articles hal-02308835v1

RMN de Paillasse à Transformée de Fourier: Le Renouveau de la RMN à Bas Champ.

Philippe Lesot
Spectra Analyse, 2017, 315, pp.32-62
Journal articles hal-02317538v1

(Cover profile) Integrated Computational Protocol for the Analysis of Quadrupolar Splittings from Natural-Abundance Deuterium NMR Spectra in (Chiral) Oriented Media

Armando Navarro-Vázquez , Philippe Berdagué , Philippe Lesot
ChemPhysChem, 2017, pp.1219-1219. ⟨10.1002/CPHC.201700454⟩
Journal articles hal-02308843v1
Image document

Contribution of NAD 2D-NMR in liquid crystals to the determination of hydrogen isotope profile of methyl groups in miliacin

Philippe Berdagué , Philippe Lesot , Jérémy Jacob , Valery T. Terwilliger , Claude Le Milbeau
Geochimica et Cosmochimica Acta, 2016, 173, pp.337-351. ⟨10.1016/j.gca.2015.10.004⟩
Journal articles insu-01225227v1
Image document

Detection of quadrupolar nuclei by ultrafast 2D NMR: exploring the case of deuterated analytes aligned in chiral oriented solvents

Philippe Lesot , Philippe Berdagué , Patrick Giraudeau
Chemical Communications, 2016, 52 (10), pp.2122-2125. ⟨10.1039/C5CC09409G⟩
Journal articles hal-02314360v1

Investigation of Solute-Fiber Affinity and Orientational Ordering of Norbornadiene Interacting with Two-Polypeptide Chiral Liquid Crystalline Solvents by Natural Abundance Deuterium (NAD) NMR

Zeinab Serhan , Christie Aroulanda , Philippe Lesot
Journal of Physical Chemistry A, 2016, 120 (30), pp.6076-6088. ⟨10.1021/acs.jpca.6b04254⟩
Journal articles hal-03004599v1

Fast acquisition of multidimensional NMR spectra of solids and mesophases using alternative sampling methods

Philippe Lesot , Krzysztof Kazimierczuk , Julien Trébosc , Jean-Paul Amoureux , Olivier Lafon
Magnetic Resonance in Chemistry, 2015, 53 (11), pp.927-939. ⟨10.1002/mrc.4290⟩
Journal articles hal-02314353v1

Enantiotopic discrimination in the NMR spectrum of prochiral solutes in chiral liquid crystals

Philippe Lesot , Christie Aroulanda , Herbert Zimmermann , Zeev Luz
Chemical Society Reviews, 2015, 44 (8), pp.2330-2375
Journal articles hal-02314352v1

Vladimir I. Bakhmutov: NMR spectroscopy in liquids and solids

Philippe Lesot
Analytical and Bioanalytical Chemistry, 2015, 407 (29), pp.8625-8626. ⟨10.1007/s00216-015-9061-z⟩
Journal articles hal-02314356v1

Synthesis and Stereochemical Assignment of Crypto-Optically Active 2-H6 -Neopentane

Ahmad Masarwa , Dennis Gerbig , Liron Oskar , Aharon Loewenstein , Hans Peter Reisenauer
Angewandte Chemie International Edition, 2015, 54 (44), pp.13106-13109. ⟨10.1002/anie.201505349⟩
Journal articles hal-03010704v1

Synthese und stereochemische Bestimmung von krypto-optisch-aktivem 2H6 -Neopentan

Ahmad Masarwa , Dennis Gerbig , Liron Oskar , Aharon Loewenstein , Hans Peter Reisenauer
Angewandte Chemie, 2015, 127 (44), pp.13298-13302. ⟨10.1002/ange.201505349⟩
Journal articles hal-02314354v1

Multi-nuclear NMR of axially chiral biaryls in polypeptide orienting solvents: spectral discriminations and enantiorecognition mechanisms

Philippe Berdagué , Jose-Enrique Herbert-Pucheta , Vishwajeet Jha , Armen Panossian , Frédéric Leroux
New Journal of Chemistry, 2015, 39 (12), pp.9504-9517. ⟨10.1039/c5nj01434d⟩
Journal articles hal-02314357v1

Chronique Littéraire: « NMR Spectroscopy in Liquid and Solids » de V. I. Bakhmutov

Philippe Lesot
Spectra Analyse, 2015, 306, pp.16-16
Journal articles hal-02317530v1

Correlation 2D-NMR experiments involving both $^{13}$C and $^{2}$H isotopes in oriented media: methodological developments and analytical applications

Philippe Lesot , Olivier Lafon , Philippe Berdagué
Magnetic Resonance in Chemistry, 2014, 52 (10), pp.595-613. ⟨10.1002/mrc.4118⟩
Journal articles hal-02314351v1

NMR discrimination in nonrigid prochiral solutes dissolved in chiral liquid crystals: symmetry considerations

Philippe Lesot , Zeev Luz , Christie Aroulanda , Herbert Zimmermann
Magnetic Resonance in Chemistry, 2014, 52 (10), pp.581-594. ⟨10.1002/mrc.4110⟩
Journal articles hal-02314350v1

RMN 2D DAN dans les CLC: de nouveaux outils pour l’étude du fractionnement isotopique naturel (2H/1H) d’acides gras et de triglycérides

Philippe Lesot
Spectra Analyse, 2014, 299 (62-72)
Journal articles hal-02317515v1

Criteria for sensitivity enhancement by compressed sensing: practical application to anisotropic NAD 2D-NMR spectroscopy

Krzysztof Kazimierczuk , Olivier Lafon , Philippe Lesot
Analyst, 2014, 139 (11), pp.2702. ⟨10.1039/c4an00381k⟩
Journal articles hal-02314349v1

Synthesis of a Mycobacterium tuberculosis tetra-acylated sulfolipid analogue and characterization of the chiral acyl chains using anisotropic NAD 2D-NMR spectroscopy.

Aurélie Lemétais , Yann Bourdreux , Philippe Lesot , Jonathan Farjon , Jean-Marie Beau
Journal of Organic Chemistry, 2013, 78 (15), pp.7648-57. ⟨10.1021/jo4012255⟩
Journal articles hal-00910978v1

Chiral solutes can seed the formation of enantiomorphic domains in a twist-bend nematic liquid crystal

James Emsley , Philippe Lesot , Geoffrey Luckhurst , Abdelkrim Meddour , Denis Merlet
Physical Review E : Statistical, Nonlinear, and Soft Matter Physics, 2013, 87 (4), ⟨10.1103/PhysRevE.87.040501⟩
Journal articles hal-02311510v1

Multiscale NMR investigation of mesogenic ionic-liquid electrolytes with strong anisotropic orientational and diffusional behaviour

Patrick Judeinstein , Stéphanie Huet , Philippe Lesot
RSC Advances, 2013, 3 (37), pp.16604. ⟨10.1039/C3RA00025G⟩
Journal articles hal-02311512v1

Synthesis of enones, pyrazolines and pyrrolines with gem-difluoroalkyl side chains

Assaad Nasr El Dine , Ali Khalaf , Danielle Gree , Olivier Tasseau , Fares Fares
Beilstein Journal of Organic Chemistry, 2013, 9, pp.1943-1948. ⟨10.3762/bjoc.9.230⟩
Journal articles hal-00871797v1

On-the-fly' Kinetics of Enzymatic Racemization using Deuterium NMR in DNA-based Chiral Oriented Media.

Monique Chan-Huot , Philippe Georges Julien Lesot , Philippe Pelupessy , Luminita Duma , Geoffrey Bodenhausen
Analytical Chemistry, 2013, 85 (9), pp.4694-4697. ⟨10.1021/ac4004002⟩
Journal articles hal-00807811v1

Analysis of NAD 2D-NMR Spectra of Saturated Fatty Acids in Polypeptide Aligning Media by Experimental and Modeling Approaches

Zeinab Serhan , Andrea Borgogno , Isabelle Billault , Alberta Ferrarini , Philippe Lesot
Chemistry - A European Journal, 2012, 18 (1), pp.117-126. ⟨10.1002/chem.201102775⟩
Journal articles hal-02143143v1

Probing substrate-product relationships by natural abundance deuterium 2D NMR spectroscopy in liquid-crystalline solvents: epoxidation of linoleate to vernoleate by two different plant enzymes

Isabelle Billault , Alicia Le Du , Minale Ouethrani , Zeinab Serhan , Philippe Lesot
Analytical and Bioanalytical Chemistry, 2012, 402 (9), pp.2985-2998. ⟨10.1007/s00216-012-5748-6⟩
Journal articles hal-02142700v1

Is Enantiomer Assignment Possible by NMR Spectroscopy Using Residual Dipolar Couplings from Chiral Nonracemic Alignment Media?-A Critical Assessment

Robert Berger , Jacques Courtieu , Roberto Gil , Christian Griesinger , Matthias Köck
Angewandte Chemie International Edition, 2012, 51 (33), pp.8388-8391. ⟨10.1002/anie.201107626⟩
Journal articles hal-02311507v1

Experimental Detection of Achiral and Chiral Naturally Abundant 13 C– 2 H Isotopomers by 2D-NMR in Liquids and Chiral Oriented Solvents

Philippe Lesot , Olivier Lafon
Analytical Chemistry, 2012, 84 (10), pp.4569-4573. ⟨10.1021/ac300667n⟩
Journal articles hal-02311506v1

Inside Cover: Analysis of NAD 2D-NMR Spectra of Saturated Fatty Acids in Polypeptide Aligning Media by Experimental and Modeling Approaches (Chem. Eur. J. 1/2012)

Zeinab Serhan , Andrea Borgogno , Isabelle Billault , Alberta Ferrarini , Philippe Lesot
Chemistry - A European Journal, 2012, 18 (1), pp.2-2. ⟨10.1002/chem.201190273⟩
Journal articles hal-02316063v1

Détection d’Isotopomères 2H-13C en Abondance Naturelle par RMN 2D Isotrope et Anisotrope, ou Comment Distinguer Expérimentalement une Molécule parmi 600 000?

Philippe Lesot , Olivier Lafon
Spectra Analyse, 2012, 287, pp.24-30
Journal articles hal-02317494v1

Analytical contribution of NAD 2D-NMR spectroscopy in polypeptide mesophases to the investigation of triglycerides

Philippe Lesot , Zeinab Serhan , Christie Aroulanda , Isabelle Billault
Magnetic Resonance in Chemistry, 2012, 50, pp.S2-S11. ⟨10.1002/mrc.3855⟩
Journal articles hal-02311508v1

La RMN en chimie organique

Jacques Courtieu , Nicolas Giraud , Olivier Lafon , Philippe Lesot , Jean-Marc Nuzillard
L'Actualité Chimique, 2012, 364-365, pp.30-41
Journal articles hal-02317465v1

Conformation and Dynamics of 18-Membered Hexathiametacyclophanes: A Two Step Racemization as Studied by Deuterium NMR in Chiral Lyotropic Liquid Crystals

Philippe Lesot , Christie Aroulanda , Philippe Berdagué , Herbert Zimmermann , Zeev Luz
Journal of Physical Chemistry B, 2011, 115 (41), pp.11793-11804. ⟨10.1021/jp205958k⟩
Journal articles hal-02311044v1

Exploring the spectral enantiodiscrimination potential of a DNA-based orienting medium using deuterium NMR spectroscopy

Philippe Lesot , U. Venkateswara Reddy , N. Suryaprakash
Chemical Communications, 2011, 47 (42), pp.11736. ⟨10.1039/C1CC15097A⟩
Journal articles hal-02311046v1

Recent advances in the analysis of the site-specific isotopic fractionation of metabolites such as fatty acids using anisotropic natural-abundance 2H NMR spectroscopy: application to conjugated linolenic methyl esters

Philippe Lesot , Zeinab Serhan , Isabelle Billault
Analytical and Bioanalytical Chemistry, 2011, 399 (3), pp.1187-1200. ⟨10.1007/s00216-010-4394-0⟩
Journal articles hal-02311033v1

Recent advances in the analysis of the site-specific isotopic fractionation of metabolites such as fatty acids using anisotropic natural-abundance H-2 NMR spectroscopy: application to conjugated linolenic methyl esters

Philippe Lesot , Zeinab Serhan , Isabelle Billault
Analytical and Bioanalytical Chemistry, 2011, 399 (3), pp.1187-1200. ⟨10.1007/s00216-010-4394-0⟩
Journal articles hal-02143481v1

Fast and High-Resolution Stereochemical Analysis by Nonuniform Sampling and Covariance Processing of Anisotropic Natural Abundance 2D 2H NMR Datasets

Olivier Lafon , Bingwen Hu , Jean-Paul Amoureux , Philippe Lesot
Chemistry - A European Journal, 2011, 17 (24), pp.6716-6724. ⟨10.1002/chem.201100461⟩
Journal articles hal-02311041v1

Enantiotopic discrimination in the deuterium NMR spectrum of solutes with S4 symmetry in chiral liquid crystals

Christie Aroulanda , Herbert Zimmermann , Zeev Luz , Philippe Lesot
The Journal of Chemical Physics, 2011, 134 (13), pp.134502. ⟨10.1063/1.3554640⟩
Journal articles hal-02311037v1

Dynamic kinetic resolution of α-chloro β-keto esters and phosphonates: hemisynthesis of Taxotere® through Ru-DIFLUORPHOS asymmetric hydrogenation

Sébastien Prevost , Sebastien Gauthier , Maria Cristina Caño de Andrade , Céline Mordant , Ali Rhida Touati
Tetrahedron: Asymmetry, 2010, 21 (11-12), pp.1436 - 1446. ⟨10.1016/j.tetasy.2010.05.017⟩
Journal articles hal-01664847v1

The conformation and orientational order of a 1,2-disubstituted ethane nematogenic molecule (I22) in liquid crystalline and isotropic phases studied by NMR spectroscopy

James Emsley , Philippe Lesot , Anne Lesage , Giuseppina de Luca , Denis Merlet
Physical Chemistry Chemical Physics, 2010, 12 (12), pp.2895. ⟨10.1039/b915587b⟩
Journal articles hal-02310986v1

Evolution of the Saupe order parameters of enantiomers from a racemic to a non-racemic liquid crystal solvent: an original light on the absolute configuration determination problem

J. Courtieu , C. Aroulanda , Philippe Lesot , A. Meddour , D. Merlet
Liquid Crystals, 2010, 37 (6-7), pp.903-912. ⟨10.1080/02678291003784164⟩
Journal articles hal-02311001v1

Cationic Planar Chiral (η 6 -Arene)Mn(CO) 3 + Complexes: Resolution, NMR Study in Chiral-Oriented Solvents, and Applications to the Enantioselective Synthesis of 4-Substituted Cyclohexenones and (η6 -Phosphinoarene)Mn(CO)3+ Complexes

Antoine Eloi , Françoise Rose-Munch , Eric Rose , Ariane Pille , Philippe Lesot
Organometallics, 2010, 29 (17), pp.3876-3886. ⟨10.1021/om100564v⟩
Journal articles hal-02316048v1

Complete determination of natural site-specific enantio-isotopomeric excesses in linoleic acid using natural abundance deuterium 2D NMR in polypeptide mesophases

Zeinab Serhan , Laura Martel , Isabelle Billault , Philippe Lesot
Chemical Communications, 2010, 46 (35), pp.6599-6601. ⟨10.1039/c0cc01486a⟩
Journal articles hal-02143503v1

Regio-defined amino[5]oxa- and thiahelicenes: A dramatic impact of the nature of the heteroatom on the helical shape and racemization barriers

Grégory Pieters , Anne Gaucher , Sylvain R A Marque , François Maurel , Philippe Lesot
Journal of Organic Chemistry, 2010, 75 (6), pp.2096-2098. ⟨10.1021/jo1000127⟩
Journal articles hal-02310992v1

Synthesis of 2-Trifluoromethyl-1,3-oxazolidines as Hydrolytically Stable Pseudoprolines

Grégory Chaume , Olivier Barbeau , Philippe Lesot , Thierry Brigaud
Journal of Organic Chemistry, 2010, 75 (12), pp.4135-4145. ⟨10.1021/jo100518t⟩
Journal articles hal-02310997v1

Enantiodiscrimination of Flexible Cyclic Solutes Using NMR Spectroscopy in Polypeptide Chiral Mesophases: Investigation of cis -Decalin and THF

Christie Aroulanda , Olivier Lafon , Philippe Lesot
Journal of Physical Chemistry B, 2009, 113 (31), pp.10628-10640. ⟨10.1021/jp902233m⟩
Journal articles hal-02310982v1

Natural abundance deuterium NMR spectroscopy: Developments and analytical applications in liquids, liquid crystals and solid phases

Philippe Lesot , Jacques Courtieu
Progress in Nuclear Magnetic Resonance Spectroscopy, 2009, 55 (2), pp.128-159. ⟨10.1016/j.pnmrs.2009.01.001⟩
Journal articles hal-02310981v1

Analysis of enantiotopic discrimination in the NMR spectra of prochiral solutes in chiral liquid crystals by symmetry factorization of the Saupe ordering matrix

Philippe Lesot , Christie Aroulanda , Zeev Luz
The Journal of Chemical Physics, 2009, 131 (10), pp.104501. ⟨10.1063/1.3197853⟩
Journal articles hal-02310983v1

Investigation of Fatty Acid Elongation and Desaturation Steps in Fusarium lateritium by Quantitative Two-dimensional Deuterium NMR Spectroscopy in Chiral Oriented Media

Vincent Baillif , Richard J. Robins , Steven Le Feunteun , Philippe Lesot , Isabelle Billault
Journal of Biological Chemistry, 2009, 284 (16), pp.10783-10792. ⟨10.1074/jbc.M807826200⟩
Journal articles hal-02143940v1

Enantiodiscrimination in Deuterium NMR Spectra of Flexible Chiral Molecules with Average Axial Symmetry Dissolved in Chiral Liquid Crystals: The Case of Tridioxyethylenetriphenylene

Philippe Lesot , Olivier Lafon , Herbert Zimmermann , Zeev Luz
Journal of the American Chemical Society, 2008, 130 (27), pp.8754-8761. ⟨10.1021/ja800957a⟩
Journal articles hal-02310973v1

Two aspects of the desymmetrization of selected prochiral aromatic or vinylic dihalides: enantioselective halogen–lithium exchange and prochiral recognition in chiral liquid crystals

Chun-An Fan , Benoit Ferber , Henri Kagan , Olivier Lafon , Philippe Lesot
Tetrahedron: Asymmetry, 2008, 19 (23), pp.2666-2677. ⟨10.1016/j.tetasy.2008.12.003⟩
Journal articles hal-02310976v1

2H NMR Studies on Two-Homopolypeptide Lyotropic Enantiodiscriminating Mesophases: Experimental Quantification of Solute-Fiber Affinities

Philippe Lesot , Olivier Lafon , Christie Aroulanda , Ronald Y. Dong
Chemistry - A European Journal, 2008, 14 (13), pp.4082-4092. ⟨10.1002/chem.200701543⟩
Journal articles hal-00298353v1

Combined analysis of C-18 unsaturated fatty acids using natural abundance deuterium 2D NMR spectroscopy in chiral oriented solvents

Philippe Lesot , Vincent Baillif , Isabelle Billault
Analytical Chemistry, 2008, 80 (8), pp.2963-2972. ⟨10.1021/ac702443b⟩
Journal articles hal-02143963v1

Enantiomeric analysis using natural abundance deuterium 3D NMR spectroscopy in polypeptide chiral oriented media

Philippe Lesot , Olivier Lafon
Chemical Physics Letters, 2008, 458 (1-3), pp.219-222. ⟨10.1016/j.cplett.2008.04.065⟩
Journal articles hal-02310970v1

RMN du deutérium en abondance naturelle dans les cristaux liquides chiraux : évolutions technologiques, avancées méthodologiques et nouvelles applications analytiques

Philippe Lesot
Spectra Analyse, 2008, 262, pp.16-22
Journal articles hal-02317421v1

Structure, Formation, and Dynamics of Mo12 and Mo16 Oxothiomolybdenum Rings Containing Terephtalate Derivatives

Jean-François Lemonnier , Sébastien Floquet , Jérôme Marrot , Emmanuel Terazzi , Claude Piguet
Chemistry - A European Journal, 2007, 13 (12), pp.3548-3557. ⟨10.1002/chem.200601369⟩
Journal articles hal-02310922v1

Homo- and heteronuclear 2D NMR approaches to analyse a mixture of deuterated unlike/like stereoisomers using weakly ordering chiral liquid crystals

Karim Ben Ali , Olivier Lafon , Herbert Zimmermann , Eric Guittet , Philippe Lesot
Journal of Magnetic Resonance, 2007, 187 (2), pp.205-215. ⟨10.1016/j.jmr.2007.04.007⟩
Journal articles hal-02310947v1

Empirical determination of the absolute configuration of small chiral molecules using natural abundance 2H NMR in chiral liquid crystals

Latifa Ziani , Philippe Lesot , Abdelkhrim Meddour , Jacques Courtieu
Chemical Communications, 2007, 45, pp.4737. ⟨10.1039/b711493a⟩
Journal articles hal-02310959v1

Chiral Discrimination in the 13 C and 2 H NMR of the Crown and Saddle Isomers of Nonamethoxy-Cyclotriveratrylene in Chiral Liquid-Crystalline Solutions

Olivier Lafon , Philippe Lesot , Herbert Zimmermann , Raphy Poupko , Zeev Luz
Journal of Physical Chemistry B, 2007, 111 (32), pp.9453-9467. ⟨10.1021/jp070564q⟩
Journal articles hal-02310954v1

Analysis of Intramolecular Dynamic Processes in Enantiomeric Diaryl Atropisomers and Related Derivatives by 2H NMR Spectroscopy in Polypeptide Liquid Crystals

Olivier Lafon , Philippe Lesot , Chun-An Fan , Henri b. Kagan
Chemistry - A European Journal, 2007, 13 (13), pp.3772-3786. ⟨10.1002/chem.200601284⟩
Journal articles hal-02310936v1

Enantioselective synthesis of methyl-5(R)-fluorohept-6-ynoate

Vijaya Lingam Manthati , A. Sai Krishna Murthy , Frédéric Caijo , Delphine Drouin , Philippe Lesot
Tetrahedron: Asymmetry, 2006, 17 (15), pp.2306-2310. ⟨10.1016/j.tetasy.2006.08.010⟩
Journal articles hal-02310918v1

Assignment of Absolute Configuration of Natural Abundance Deuterium Signals Associated with ( R )- and ( S )-Enantioisotopomers in a Fatty Acid Aligned in a Chiral Liquid Crystal: Enantioselective Synthesis and NMR Analysis

Vincent Baillif , Richard Robins , Isabelle Billault , Philippe Lesot
Journal of the American Chemical Society, 2006, 128 (34), pp.11180-11187. ⟨10.1021/ja0617892⟩
Journal articles hal-02310912v1

Study of molecular rotational isomerism using deuterium NMR in chiral oriented solvents

Philippe Lesot , Olivier Lafon , Henri Kagan , Chun-An Fan
Chemical Communications, 2006, 4, pp.389-391. ⟨10.1039/b514694a⟩
Journal articles hal-02310907v1

Enantiomeric Analysis of Planar Chiral (η 6 -Arene)chromium Tricarbonyl Complexes using NMR in Oriented Solvents

Olivier Lafon , Philippe Lesot , Françoise Rose-Munch , Eric Rose
Organometallics, 2005, 24 (16), pp.4021-4028. ⟨10.1021/om050239u⟩
Journal articles hal-02310905v1

Theoretical and experimental investigation of 13C relayed 2H–2H-COSY 2D experiments: Application to the analysis of weakly aligned solutes

Olivier Lafon , Philippe Lesot
Journal of Magnetic Resonance, 2005, 174 (2), pp.254-264. ⟨10.1016/j.jmr.2005.02.011⟩
Journal articles hal-02310894v1

Deuterium 3D NMR experiments for analysing weakly aligned, isotopically enriched solutes

Olivier Lafon , Philippe Lesot
Chemical Physics Letters, 2005, 404 (1-3), pp.90-94. ⟨10.1016/j.cplett.2005.01.040⟩
Journal articles hal-02310889v1

Enantiomeric Analysis of Planar Chiral (η6-Arene)chromium Tricarbonyl Complexes using NMR in Oriented Solvents

Olivier Lafon , Philippe Lesot , Michaël Rivard , Murielle Chavarot-Kerlidou , Françoise Rose-Munch
Organometallics, 2005, 24, pp.4021 - 4028. ⟨10.1021/om050239u⟩
Journal articles hal-04013449v1

Développement et Applications de la RMN du Deutérium en Abondance Naturelle dans les Cristaux Liquides Chiraux: Une autre Approche de l’Analyse en Chimie Organique

Philippe Lesot
Spectra Analyse, 2005, 242, pp.37-42
Journal articles hal-02317383v1

Modified z-gradient filtering as a mean to obtain phased deuterium autocorrelation 2D NMR spectra in oriented solvents

Olivier Lafon , Denis Merlet , Jacques Courtieu , Philippe Lesot
Journal of Magnetic Resonance, 2004, 171 (1), pp.135-142. ⟨10.1016/j.jmr.2004.08.010⟩
Journal articles hal-02310847v1

Heteronuclear selective refocusing 2D NMR experiments for the spectral analysis of enantiomers in chiral oriented solvents

Jonathan Farjon , Jean-Pierre Baltaze , Philippe Lesot , Denis Merlet , Jacques Courtieu
Magnetic Resonance in Chemistry, 2004, 42 (7), pp.594-599. ⟨10.1002/mrc.1399⟩
Journal articles hal-03008490v1

The orientational order and conformational distributions of the two enantiomers in a racemic mixture of a chiral, flexible molecule dissolved in a chiral nematic liquid crystalline solvent

James Emsley , Philippe Lesot , Denis Merlet
Physical Chemistry Chemical Physics, 2004, 6 (3), pp.522. ⟨10.1039/b312512b⟩
Journal articles hal-02310778v1

New amino acid-based anionic surfactants and their use as enantiodiscriminating lyotropic liquid crystalline NMR solvents

Krystyna Baczko , Chantal Larpent , Philippe Lesot
Tetrahedron: Asymmetry, 2004, 15 (6), pp.971-982. ⟨10.1016/j.tetasy.2004.01.022⟩
Journal articles hal-02310787v1

The effect of a chiral nematic solvent on the orientational order and conformational distribution of a flexible prochiral solute

James W. Emsley , Philippe Lesot , Jacques Courtieu , Denis Merlet
Physical Chemistry Chemical Physics, 2004, 6 (23), pp.5331. ⟨10.1039/b411203b⟩
Journal articles hal-02310857v1

Analysis of the13C NMR Spectra of Molecules, Chiral by Isotopic Substitution, Dissolved in a Chiral Oriented Environment: Towards the Absolute Assignment of the pro-R/pro-S Character of Enantiotopic Ligands in Prochiral Molecules

Philippe Lesot , Olivier Lafon , Jacques Courtieu , Philippe Berdagué
Chemistry - A European Journal, 2004, 10 (15), pp.3741-3746. ⟨10.1002/chem.200400065⟩
Journal articles hal-02310803v1

Exploring the Analytical Potential of NMR Spectroscopy in Chiral Anisotropic Media for the Study of the Natural Abundance Deuterium Distribution in Organic Molecules

Philippe Lesot , Christie Aroulanda , Isabelle Billault
Analytical Chemistry, 2004, 76 (10), pp.2827-2835. ⟨10.1021/ac030385e⟩
Journal articles hal-03008466v1

Efficient enantiodiscrimination of chiral monophosphine oxides and boranes by phosphorus coupled 13C NMR spectroscopy in the presence of chiral ordering agents

Michael Rivard , F. Guillen , Jean-Claude Fiaud , Christie Aroulanda , Philippe Lesot
Tetrahedron: Asymmetry, 2003, 14 (9), pp.1141-1152. ⟨10.1016/S0957-4166(03)00202-7⟩
Journal articles hal-02310631v1

Efficient enantiodiscrimination of chiral monophosphine oxides and boranes by phosphorus coupled 13C NMR spectroscopy in the presence of chiral ordering agents

Michaël Rivard , F. Guillen , Jean-Claude Fiaud , Christie Aroulanda , Philippe Lesot
Tetrahedron: Asymmetry, 2003, 14 (9), pp.1141. ⟨10.1016/S0957-4166(03)00202-7⟩
Journal articles hal-01146992v1

Structural Ambiguities Revisited in Two Bridged Ring Systems Exhibiting Enantiotopic Elements, Using Natural Abundance Deuterium NMR in Chiral Liquid Crystals

Christie Aroulanda , Denis Merlet , Jacques Courtieu , Philippe Lesot
Journal of Physical Chemistry A, 2003, 107 (50), pp.10911-10918. ⟨10.1021/jp030137m⟩
Journal articles hal-02310640v1

2D-NMR Strategy Dedicated to the Analysis of Weakly Ordered, Fully Deuterated Enantiomers in Chiral Liquid Crystals

Philippe Lesot , Muriel Sarfati , Denis Merlet , Bernard Ancian , James Emsley
Journal of the American Chemical Society, 2003, 125 (25), pp.7689-7695. ⟨10.1021/ja021277x⟩
Journal articles hal-02310635v1

Enantiomeric and Enantiotopic Analysis of Cone-Shaped Compounds with C 3 and C 3 v Symmetry Using NMR Spectroscopy in Chiral Anisotropic Solvents

Philippe Lesot , Denis Merlet , Muriel Sarfati , Jacques Courtieu , Herbert Zimmermann
Journal of the American Chemical Society, 2002, 124 (34), pp.10071-10082. ⟨10.1021/ja020269d⟩
Journal articles hal-02310599v1

Investigation of SmI2-mediated cyclisation of δ-iodo-α,β-unsaturated esters by deuterium 2D NMR in oriented solvents

Hélène Villar , François Guibé , Christie Aroulanda , Philippe Lesot
Tetrahedron: Asymmetry, 2002, 13 (14), pp.1465-1475. ⟨10.1016/S0957-4166(02)00259-8⟩
Journal articles hal-02310609v1

Résonance Magnétique Nucléaire du Deutérium en Abondance Naturelle dans les Cristaux Liquide Chiraux: Franchir une Nouvelle Frontière dans l'Analyse de la Chiralité

Philippe Lesot
Lettre du Département des Sciences Chimiques du CNRS, 2002, 78, pp.13-17
Journal articles hal-02321165v1

Routine Use of Natural Abundance Deuterium NMR in a Polypeptidic Chiral Oriented Solvent for the Determination of the Enantiomeric Composition of Chiral Building Blocks

Arnaud Parenty , Jean-Marc Campagne , Christie Aroulanda , Philippe Lesot
Organic Letters, 2002, 4 (10), pp.1663-1666. ⟨10.1021/ol020038b⟩
Journal articles hal-00165644v1

Enantiomeric excess measurements in weakly oriented chiral liquid crystal solvents through 2D 1H selective refocusing experiments

Jonathan Farjon , Denis Merlet , Philippe Lesot , Jacques Courtieu
Journal of Magnetic Resonance, 2002, 158 (1-2), pp.169-172. ⟨10.1016/S1090-7807(02)00070-8⟩
Journal articles hal-02310612v1

First successful enantiomeric discrimination of chiral alkanes using NMR spectroscopy

Muriel Sarfati , Jacques Courtieu , Philippe Lesot
Chemical Communications, 2001, 13, pp.1113-1114. ⟨10.1039/b002806l⟩
Journal articles hal-02309085v1

Enantiomeric recognition of chiral invertomers through NMR in chiral oriented phases: a study of cis-decalin

Muriel Sarfati , Christie Aroulanda , Jacques Courtieu , Philippe Lesot
Tetrahedron: Asymmetry, 2001, 12 (5), pp.737-744. ⟨10.1016/S0957-4166(01)00103-3⟩
Journal articles hal-02309129v1

Determining Enantiomeric Purity by NMR: Deuterium 2D NMR at Natural Abundance in Weakly Oriented Chiral Liquid Crystals

Philippe Lesot , Muriel Sarfati , Denis Merlet , Jacques Courtieu , Bernard Ancian
Bruker Report, 2001, 149, pp.29-33
Journal articles hal-02321012v1

NMR Experimental Evidence of the Differentiation of Enantiotopic Directions in Cs and C2v Molecules Using Partially Oriented, Chiral Media

Christie Aroulanda , Denis Merlet , Jacques Courtieu , Philippe Lesot
Journal of the American Chemical Society, 2001, 123 (48), pp.12059-12066. ⟨10.1021/ja011685l⟩
Journal articles hal-02309135v1

Enantiomeric recognition of chiral invertomers through NMR in chiral oriented phases: a study of cis-decalin

Muriel Sarfati , Christie Aroulanda , Jacques Courtieu , Philippe Lesot
Tetrahedron: Asymmetry, 2001, 12 (5), pp.737-744. ⟨10.1016/S0957-4166(01)00103-3⟩
Journal articles hal-02338088v1

Theoretical and experimental aspects of enantiomeric differentiation using natural abundance multinuclear nmr spectroscopy in chiral polypeptide liquid crystals

Muriel Sarfati , Philippe Lesot , Denis Merlet , Jacques Courtieu
Chemical Communications, 2000, 21, pp.2069-2081. ⟨10.1039/B006244H⟩
Journal articles hal-02309126v1

Highly enantioselective propargylic monofluorination established by carbon-13 and fluorine-19 NMR in chiral liquid crystals

Valérie Madiot , Philippe Lesot , Danielle Gree , Jacques Courtieu , René Grée
Chemical Communications, 2000, 2, pp.169-170. ⟨10.1039/A909012F⟩
Journal articles hal-02309109v1

Deuterium NMR stereochemical analysis of threo–erythro isomers bearing remote stereogenic centres in racemic and non-racemic liquid crystalline solvents

Cécile Canlet , Denis Merlet , Philippe Lesot , Abdelkrim Meddour , Jacques Courtieu
Tetrahedron: Asymmetry, 2000, 11 (9), pp.1911-1918. ⟨10.1016/S0957-4166(00)00125-7⟩
Journal articles hal-02309123v1

Description of natural abundance deuterium 2D-NMR experiments in weakly ordered liquid-crystalline solvents using a tailored cartesian spin-operator formalism

Denis Merlet , Muriel Sarfati , Bernard Ancian , Jacques Courtieu , Philippe Lesot
Physical Chemistry Chemical Physics, 2000, 2 (10), pp.2283-2290. ⟨10.1039/b000834f⟩
Journal articles hal-02309116v1

Two-Dimensional Deuterium NMR Spectroscopy of Chiral Molecules Oriented in a Polypeptide Liquid Crystal: Applications for the Enantiomeric Analysis through Natural Abundance Deuterium NMR

Denis Merlet , Bernard Ancian , Jacques Courtieu , Philippe Lesot
Journal of the American Chemical Society, 1999, 121 (22), pp.5249-5258. ⟨10.1021/ja9837699⟩
Journal articles hal-02309106v1

The relationship between molecular symmetry and second-rank orientational order parameters for molecules in chiral liquid crystalline solvents

Denis Merlet , James Emsley , Philippe Lesot , Jacques Courtieu
The Journal of Chemical Physics, 1999, 111 (15), pp.6890-6896. ⟨10.1063/1.479982⟩
Journal articles hal-02309108v1

Double diastereoselection in asymmetric [2+3] cycloaddition of chiral oxazoline N-oxides: application to the kinetic resolution of a racemic α,β-unsaturated δ-lactone

Olivier Dirat , Cyrille Kouklovsky , Yves Langlois , Philippe Lesot , Jacques Courtieu
Tetrahedron: Asymmetry, 1999, 10 (16), pp.3197-3207. ⟨10.1016/S0957-4166(99)00317-1⟩
Journal articles hal-02309107v1

Structural–dynamical relationship in silica PEG hybrid gels

Philippe Lesot , Séverin Chapuis , Jean Pierre Bayle , Jacques Rault , Eric Lafontaine
Journal of Materials Chemistry, 1998, 8 (1), pp.147-151. ⟨10.1039/A704983H⟩
Journal articles hal-02309086v1

Simplification of19F NMR Spectra of Liquid Crystalline Samples by Multiple-Pulse COSY Experiments

Philippe Lesot , James Emsley , Jean-Michel Ouvrard , Eirian Curzon
Journal of Magnetic Resonance, 1998, 133 (1), pp.166-172. ⟨10.1006/jmre.1998.1452⟩
Journal articles hal-02309101v1

Analysis of natural abundance deuterium NMR spectra of enantiomers in chiral liquid crystals via 2D auto-correlation experiments

Denis Merlet , Bernard Ancian , William Smadja , Jacques Courtieu , Philippe Lesot
Chemical Communications, 1998, 21, pp.2301-2302. ⟨10.1039/A805020A⟩
Journal articles hal-02309103v1

Quantitative Description of the Facial Discrimination of Molecules Containing a Prochiral Group by NMR in a Chiral Liquid Crystal

D. Merlet , A. Loewenstein , W. Smadja , J. Courtieu , Philippe Lesot
Journal of the American Chemical Society, 1998, 120 (5), pp.963-969. ⟨10.1021/ja9726466⟩
Journal articles hal-02309088v1

Enantiomeric visualization using proton-decoupled natural abundance deuterium NMR in poly(γ-benzyl-l-glutamate) liquid crystalline solutions

Philippe Lesot , Denis Merlet , Aharon Loewenstein , Jacques Courtieu
Tetrahedron: Asymmetry, 1998, 9 (11), pp.1871-1881. ⟨10.1016/S0957-4166(98)00179-7⟩
Journal articles hal-02309102v1

Calculation of the Molecular Ordering Parameters of (±)-3-Butyn-2-ol Dissolved in an Organic Solution of Poly(γ-benzyl- l -glutamate)

Philippe Lesot , Denis Merlet , Jacques Courtieu , James Emsley , Tapio Rantala
Journal of Physical Chemistry A, 1997, 101 (31), pp.5719-5724. ⟨10.1021/jp9709262⟩
Journal articles hal-02309087v1

Steric Hindrance Influence of a Diazo Link upon Mesogenic Properties of some Ligands and Related Copper Complexes

Philippe Lesot , Felix Perez , Patrick Judeinstein , Jean Pierre Bayle , Hassan Allouchi
Journal de Chimie Physique, 1997, 94, pp.1695-1714
Journal articles hal-02320964v1

Proton-decoupled carbon-13 NMR spectroscopy in a lyotropic chiral nematic solvent as an analytical tool for the measurement of the enantiomeric excess

A. Meddour , P. Berdague , A. Hedli , J. Courtieu , Philippe Lesot
Journal of the American Chemical Society, 1997, 119 (19), pp.4502-4508. ⟨10.1021/ja964002o⟩
Journal articles hal-02324618v1

Discrimination and analysis of the NMR spectra of enantiomers dissolved in chiral liquid crystal solvents through 2D correlation experiments

Philippe Lesot , Denis Merlet , Jacques Courtieu , J. Emsley
Liquid Crystals, 1996, 21 (3), pp.427-435. ⟨10.1080/02678299608032851⟩
Journal articles hal-02308703v1

Visualization of enantiomers in a polypeptide liquid-crystal solvent through carbon-13 NMR spectroscopy

Philippe Lesot , Denis Merlet , Abdelkrim Meddour , Jacques Courtieu , Aharon Loewenstein
Journal of the Chemical Society, Faraday Transactions, 1995, 91 (9), pp.1371. ⟨10.1039/ft9959101371⟩
Journal articles hal-02309082v1

Measurement and Analysis of the Molecular Ordering Tensors of Two Enantiomers Oriented in a Polypeptide Liquid Crystalline System

Philippe Lesot , Yves Gounelle , Denis Merlet , Aharon Loewenstein , Jacques Courtieu
The Journal of physical chemistry, 1995, 99 (40), pp.14871-14875. ⟨10.1021/j100040a042⟩
Journal articles hal-02309083v1

Coherent Reduction of Dipolar Interactions in Molecules Dissolved in Anisotropic Media Using a New Multiple-Pulse Sequence in a COSY Experiment

Philippe Lesot , J.M. Ouvrard , B.N. Ouvrard , J. Courtieu
Journal of magnetic resonance. Series A, 1994, 107 (2), pp.141-150. ⟨10.1006/jmra.1994.1061⟩
Journal articles hal-02309080v1

Multiple-pulse COSY NMR spectroscopy of oriented molecules in thermotropic cholesteric

Philippe Lesot , F. Nielsen , J. Ouvrard , J. Courtieu
The Journal of physical chemistry, 1994, 98 (49), pp.12849-12855. ⟨10.1021/j100100a009⟩
Journal articles hal-02309081v1

Acquisition rapide de spectres RMN multidimensionnels de solides en utilisant des échantillonnages alternatifs

Olivier Lafon , Julien Trebosc , Eriks Kupče , Philippe Lesot , Jean-Paul Amoureux
Groupement d'Etudes de Résonance Magnétique (GERM), May 2019, Saint Pierre d’Oléron, France
Conference papers hal-04438434v1

(D/H) Isotopic Fractionation by Anisotropic NAD 2D-NMR Spectroscopy: Exploiting the Analytical Wealth of Oriented Solvents to Investigate Molecules of Interest

Philippe Lesot , Philippe Berdagué , Jérémy Jacob
8th International Symposium on Isotopomers, Oct 2016, Nantes, France
Conference papers hal-01401863v1

Conditions environnementales, biosynthèses, diagenèse : contribution analytique de la RMN 2H en milieu anisotrope

Philippe Berdagué , Jérémy Jacob , Valery J. Terwilliger , Claude Le Milbeau , Philippe Lesot
4èmes Journées Climat et Impacts, Nov 2016, Orsay, France
Conference papers hal-01689725v1

Miliacin from broomcorn millet – a fossil molecule of multiple interests for archaeologists and paleoenvironmentalists

Jérémy Jacob , Anaëlle Simonneau , Nicolas Bossard , Claude Le Milbeau , Marlène Lavrieux
Millet Cultivation in the Caucasus from the 6th to the 2nd mill BC: Origin and Development, Nov 2015, Lyon, France
Conference papers hal-01400923v1
Image document

Chiral imines on the wave: reactivity of tert-butyl acrylate and stereoselectivity determination using NMR in liquid crystals

Lucie Vandromme , Li Chen , Lai Wei , Franck Le Bideau , André Loupy
MOL2NET, International Conference on Multidisciplinary Sciences, 2015, SCIForum, France. pp.1-18, ⟨10.3390/MOL2NET-1-a003⟩
Conference papers hal-02314359v1

Contribution de la RMN 2D DAN anisotrope à la détermination du profil isotopique (D/H) i dans des biomarqueurs: étude de la miliacine

Philippe Berdagué , Jérémy Jacob , Valerie Terwilliger , Claude Lemilbeau , Philippe Lesot
Colloque RMN GBP-Ile de France, May 2015, Gif-sur-Yvette, France
Conference papers hal-01400951v1
Image document

Hydrogen Isotope Profile of Methyl Groups in Miliacin (olean-18-en-3βol ME) by Natural Abundance Deuterium 2D-NMR Spectroscopy in liquid crystals

Philippe Berdagué , Philippe Lesot , Jérémy Jacob , Valery T. Terwilliger , Claude Le Milbeau
the 26th International Meeting on Organic Geochemistry (IMOG 2013), Sep 2013, Tenerife, Spain. 3p
Conference papers insu-00843521v1

Methodological Study of the Peptide Coupling of the N-desactivated Stable Proline Surrogate CF3-pseudoproline

Grégory Chaume , Olivier Barbeau , Philippe Lesot , Emeric Miclet , Thierry Brigaud
32nd European Peptide Symposium, 2012, Sitges, France. pp.S58-S200, ⟨10.1002/psc.2449⟩
Conference papers hal-02316083v1
Image document

Specific Natural Isotope Fractionation Studied by 2H Nuclear Magnetic Resonance (SNIF-NMR): History, Developments, and Applications

Philippe Lesot , Gérald Remaud , Ben-Li Zhang
Handbook of Isotopologue Biogeochemistry, Springer Nature Singapore, pp.1-41, 2023, ⟨10.1007/978-981-10-7048-8_38-1⟩
Book sections hal-04215287v1
Image document

Anisotropic 1D/2D NMR in Molecular Analysis

Philippe Lesot , Roberto R. Gil
K. Ivanov; P.K. Madhu; G. Rajalakshmi. Two-Dimensional (2D) NMR Methods, Wiley, pp.209-296, 2023, ⟨10.1002/9781119806721.ch9⟩
Book sections hal-04218745v1
Image document

Combining Fast 2D NMR Methods and Oriented Media

Philippe Lesot , Olivier Lafon
Jean-Nicolas Dumez; Patrick Giraudeau. Fast 2D Solution-state NMR: Concepts and Applications, 1, The Royal Society of Chemistry, 2023, 978-1-83916-400-2. ⟨10.1039/BK9781839168062-00441⟩
Book sections hal-04207389v1
Image document

Nuclear Magnetic Resonance Spectroscopy-Applicable Elements—Hydrogen Isotopes: 2 H NMR

Philippe Lesot
Reference Module in Chemistry, Molecular Sciences and Chemical Engineering, 7, Elsevier, pp.152-167, 2018, ⟨10.1016/B978-0-12-409547-2.14084-3⟩
Book sections hal-02334009v1

Isotope Ratio Monitoring by NMR. Part 1: Recent Advances

Gérald Remaud , Patrick Giraudeau , Philippe Lesot , Serge Akoka
Ed. G. Webb. Modern Magnetic Resonance, 2nd Edition, 1-25, Springer International Publishing, 2017, 978-3-319-28275-6. ⟨10.1007/978-3-319-28275-6⟩
Book sections hal-02308872v1

Isotope Ratio Monitoring by NMR. Part 2: New Applications in the Field of Defining Biosynthesis

Richard J. Robins , Gérald Remaud , Isabelle Billault , Philippe Lesot
Ed. G. Webb. Modern Magnetic Resonance, 2nd Edition, Springer International Publishing, pp.1-26, 2017, 978-3-319-28275-6. ⟨10.1007/978-3-319-28275-6_9-1⟩
Book sections hal-02321193v1

Natural Abundance Deuterium NMR Spectroscopy

Philippe Lesot , Olivier Lafon
Encyclopedia of Spectroscopy and Spectrometry, Elsevier, pp.1-14, 2016, ⟨10.1016/B978-0-12-409547-2.12110-9⟩
Book sections hal-02308860v1

Rapport de Conjoncture du CoNRS 2014 (INC / Section 12)

Chantal Andraud , Philippe Belmont , J.M. Campagne , Gaëlle Chouraqui , Emmanuel Gras
CNRS Editions, Paris,. Rapport de Conjoncture du CoNRS 2014, CNRS Editions, Paris,, pp.255-274, 2014, 978-2-271-08746-1
Book sections hal-02338362v1

Deuterium NMR of Liquid-crystalline Samples at Natural Abundance

Philippe Lesot
Encyclopedia of Magnetic Resonance (eMagRes, 2 (3), John Wiley & Sons, Ltd, pp.315-334, 2013, 780470034590. ⟨10.1002/9780470034590⟩
Book sections hal-02316109v1

Architectures moléculaires : synthèses, mécanismes et propriétés

Chantal Andraud , Janick Ardisson , Didier Bourissou , Elisabet Dunach , J.C. Guillemin
Rapport de Conjoncture du Comité national de la recherche scientifique 2010, CNRS éditions, pp.231-242, 2011, 978-2-271-07263-4
Book sections hal-02338332v1

Analytical Potentials of Natural Abundance Deuterium NMR Spectroscopy In Achiral Thermotropics and Polypeptide Chiral Liquid Crystals

Philippe Lesot , Christie Aroulanda
World Scientific Publishing Co. Pte. Ltd. NMR Spectroscopy of Liquid Crystals,, pp.37-78, 2010
Book sections hal-02317644v1

Deuterium NMR of Liquid-crystalline Samples at Natural Abundance

Philippe Lesot
EMagRes (Encyclopedia of Magnetic Resonance), 9 (37), John Wiley & Sons, Ltd, pp.1943-1948, 2007, ⟨10.1002/9780470034590.emrstm1318⟩
Book sections hal-03008886v1

Chiral Liquid Crystal NMR: a Tool for Enantiomeric Analysis

Jacques Courtieu , Philippe Lesot , Denis Merlet , Abdelkrim Meddour , Christie Aroulanda
Eds. D.M. Grant & R.K. Harris, J. Wiley & Sons. Encyclopedia of NMR: Advances in NMR", 1st print edition, 9, pp.497-505, 2002
Book sections hal-02321152v1