Pierre Daumar

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Publications

P-gp quantification for cell resistance studies in leukemia cells using the innovative LightSpot-FL-1 fluorescent conjugate

Maxime Dubois , Antoine Goisnard , Céline Bourgne , Elodie Gay , Marie Depresle et al.

Scientific Reports, 2025, 15 (1), pp.18173. ⟨10.1038/s41598-025-03370-4⟩

Article dans une revue hal-05423039v1

Development of a liquid overlay-based three-dimensional cell culture panel for drug screening applications

Marie Depresle , Pierre Daumar , Antoine Goisnard , Manon Roux , Corinne Aubel et al.

Scientific Reports, 2025, 15 (1), pp.42989. ⟨10.1038/s41598-025-26985-z⟩

Article dans une revue hal-05423211v1

LightSpot Fluorescent Conjugates as Highly Efficient Tools for Lysosomal P-gp Quantification in Olaparib-Treated Triple-Negative Breast Cancer Cells

Antoine Goisnard , Pierre Daumar , Maxime Dubois , Elodie Gay , Manon Roux et al.

International Journal of Molecular Sciences, 2025, 26 (14), pp.6675. ⟨10.3390/ijms26146675⟩

Article dans une revue hal-05423415v1
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Chemical biology fluorescent tools for in vitro investigation of the multidrug resistant P-glycoprotein (P-gp) expression in tumor cells

Pierre Daumar , Antoine Goisnard , Clémence Dubois , Manon Roux , Marie Depresle et al.

RSC Advances, 2023, 13 (39), pp.27016-27035. ⟨10.1039/d3ra05093a⟩

Article dans une revue hal-04204514v1
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LightSpot®-FL-1 Fluorescent Probe: An Innovative Tool for Cancer Drug Resistance Analysis by Direct Detection and Quantification of the P-glycoprotein (P-gp) on Monolayer Culture and Spheroid Triple Negative Breast Cancer Models

Antoine Goisnard , Pierre Daumar , Clémence Dubois , Corinne Aubel , Manon Roux et al.

Cancers, 2021, 13 (16), pp.4050. ⟨10.3390/cancers13164050⟩

Article dans une revue hal-03333862v1
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The New Serum-Free OptiPASS® Medium in Cold and Oxygen-Free Conditions: An Innovative Conservation Method for the Preservation of MDA-MB-231 Triple Negative Breast Cancer Spheroids

Antoine Goisnard , Clémence Dubois , Pierre Daumar , Corinne Aubel , Marie Depresle et al.

Cancers, 2021, 13 (8), pp.1945. ⟨10.3390/cancers13081945⟩

Article dans une revue hal-03220635v1

The New Synthetic Serum-Free Medium OptiPASS Promotes High Proliferation and Drug Efficacy Prediction on Spheroids from MDA-MB-231 and SUM1315 Triple-Negative Breast Cancer Cell Lines

Clémence Dubois , Pierre Daumar , Corinne Aubel , Jean Gauthier , Bernard Vidalinc et al.

Journal of Clinical Medicine Research, 2019, 8 (3), pp.397. ⟨10.3390/jcm8030397⟩

Article dans une revue hal-02091079v1
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Low-Dose and Long-Term Olaparib Treatment Sensitizes MDA-MB-231 and SUM1315 Triple-Negative Breast Cancers Spheroids to Fractioned Radiotherapy

Clémence Dubois , Fanny Martin , Chervin Hassel , Florian Magnier , Pierre Daumar et al.

Journal of Clinical Medicine, 2019, 9 (1), pp.64. ⟨10.3390/jcm9010064⟩

Article dans une revue hal-03121822v1
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Cytotoxicity Study of Gold Nanoparticles on the Basal-Like Triple-Negative HCC-1937 Breast Cancer Cell Line

Christophe Massard , Clémence Dubois , Vincent Raspal , Pierre Daumar , Yves Sibaud et al.

Journal of Biomaterials and Nanobiotechnology, 2018, 09 (01), pp.13 - 25. ⟨10.4236/jbnb.2018.91002⟩

Article dans une revue hal-01829452v1
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Development and validation of a high-performance liquid chromatography method for the quantitation of intracellular PARP inhibitor Olaparib in cancer cells

Pierre Daumar , Robin Dufour , Clémence Dubois , Frédérique Penault-Llorca , Mahchid Bamdad et al.

Journal of Pharmaceutical and Biomedical Analysis, 2018, 152, pp.74-80. ⟨10.1016/j.jpba.2018.01.036⟩

Article dans une revue hal-03121699v1
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Development and cytotoxic response of two proliferative MDA- MB-231 and non-proliferative SUM1315 three-dimensional cell culture models of triple-negative basal-like breast cancer cell lines

Clémence Dubois , Robin Dufour , Pierre Daumar , Corinne Aubel , Claire Szczepaniak et al. Article dans une revue hal-01651313v1
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BCRP and P-gp relay overexpression in triple negative basal-like breast cancer cell line: a prospective role in resistance to Olaparib

Robin Dufour , Pierre Daumar , Emmanuelle Mounetou , Corinne Aubel , Fabrice Kwiatkowski et al.

Scientific Reports, 2015, 5 (1), ⟨10.1038/srep12670⟩

Article dans une revue hal-03124552v1

Synthesis and evaluation of 18F-labeled ATP competitive inhibitors of topoisomerase II as probes for imaging topoisomerase II expression

Pierre Daumar , Brian Zeglis , Nicholas Ramos , Vadim Divilov , Kuntal Kumar Sevak et al.

European Journal of Medicinal Chemistry, 2014, 86, pp.769-781. ⟨10.1016/j.ejmech.2014.09.019⟩

Article dans une revue hal-03121843v1

Efficient 18 F-Labeling of Large 37-Amino-Acid pHLIP Peptide Analogues and Their Biological Evaluation

Pierre Daumar , Cindy Wanger-Baumann , Nagavarakishore Pillarsetty , Laura Fabrizio , Sean Carlin et al.

Bioconjugate Chemistry, In press, 23 (8), pp.1557-1566. ⟨10.1021/bc3000222⟩

Article dans une revue hal-03121688v1

The Next Generation of Positron Emission Tomography Radiopharmaceuticals in Oncology

Samuel Rice , Celeste Roney , Pierre Daumar , Jason Lewis

Seminars in Nuclear Medicine, 2011, 41 (4), pp.265-282. ⟨10.1053/j.semnuclmed.2011.02.002⟩

Article dans une revue hal-03121722v1

Design, synthesis and in vitro drug release investigation of new potential 5-FU prodrugs

Pierre Daumar , Caroline Decombat , Jean-Michel Chezal , Eric Debiton , Michel Madesclaire et al.

European Journal of Medicinal Chemistry, 2011, 46 (7), pp.2867-2879. ⟨10.1016/j.ejmech.2011.04.010⟩

Article dans une revue istex hal-03121824v1