Pierre-Emmanuel Gleizes

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Publications

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Off-axis electron holography of unstained bacteriophages: Towards electrostatic potential measurement of biological samples

Elio Karim , Christophe Gatel , Amélie Leforestier , Stéphanie Balor , Vanessa Soldan et al.
Journal of Structural Biology, 2025, 217 (1), pp.108169. ⟨10.1016/j.jsb.2025.108169⟩
Article dans une revue hal-04901847 v1
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SURF2 is a MDM2 antagonist in triggering the nucleolar stress response

Sophie Tagnères , Paulo Espirito Santo , Julie Radermecker , Dana Rinaldi , Carine Froment et al.
Nature Communications, 2024, 15 (1), pp.8404. ⟨10.1038/s41467-024-52659-x⟩
Article dans une revue hal-04739145 v1

Collectively building a mentor–mentee relationship through a one-day workshop

Sophie Tagnères , Paulo Espirito Santo , Julie Radermecker , Dana Rinaldi , Carine Froment et al.
Nature Biotechnology, 2023, 41 (12), pp.1829-1833. ⟨10.1038/s41587-023-02056-4⟩
Article dans une revue hal-04827523 v1
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HEATR3 variants impair nuclear import of uL18 (RPL5) and drive Diamond-Blackfan anemia

Marie-Françoise O'Donohue , Lydie da Costa , Marco Lezzerini , Sule Unal , Clément Joret et al.
Blood, 2022, 139 (21), pp.3111-3126. ⟨10.1182/blood.2021011846⟩
Article dans une revue hal-03664461 v1
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Functionally impaired RPL8 variants associated with Diamond–Blackfan anemia and a Diamond–Blackfan anemia‐like phenotype

Simon Lebaron , Marie-Françoise O'Donohue , Scott Smith , Kendra Engleman , Jane Juusola et al.
Human Mutation, 2022, 43 (3), pp.389-402. ⟨10.1002/humu.24323⟩
Article dans une revue hal-03664473 v1
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The final step of 40S ribosomal subunit maturation is controlled by a dual key lock

Laura Plassart , Ramtin Shayan , Christian Montellese , Dana Rinaldi , Natacha Larburu et al.
eLife, 2021, 10, pp.e61254. ⟨10.7554/eLife.61254⟩
Article dans une revue hal-03383808 v2

Human METTL18 is a histidine-specific methyltransferase that targets RPL3 and affects ribosome biogenesis and function

Jędrzej Małecki , Marie-Francoise Odonohue , Yeji Kim , Magnus Jakobsson , Luca Gessa et al.
Nucleic Acids Research, 2021, 49 (6), pp.3185-3203. ⟨10.1093/nar/gkab088⟩
Article dans une revue hal-03363245 v1

p53 activation during ribosome biogenesis regulates normal erythroid differentiation

Salomé Le Goff , Ismael Boussaid , Celia Floquet , Anna Raimbault , Isabelle Hatin et al.
Blood, 2021, 137 (1), pp.89-102. ⟨10.1182/blood.2019003439⟩
Article dans une revue hal-03442857 v1
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The human methyltransferase ZCCHC4 catalyses N6-methyladenosine modification of 28S ribosomal RNA

Rita Pinto , Cathrine B Vågbø , Magnus E Jakobsson , Yeji Kim , Marijke P Baltissen et al.
Nucleic Acids Research, 2020, 48 (2), pp.830 - 846. ⟨10.1093/nar/gkz1147⟩
Article dans une revue hal-02989962 v1
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Good Vibrations: Structural Remodeling of Maturing Yeast Pre-40S Ribosomal Particles Followed by Cryo-Electron Microscopy

Ramtin Shayan , Dana Rinaldi , Natacha Larburu , Laura Plassart , Stéphanie Balor et al.
Molecules, 2020, 25 (5), pp.1125. ⟨10.3390/molecules25051125⟩
Article dans une revue hal-02998843 v1

NHP2 deficiency impairs rRNA biogenesis and causes pulmonary fibrosis and Høyeraal-Hreidarsson syndrome

Maname Benyelles , Marie-Françoise O'Donohue , Laëtitia Kermasson , Elodie Lainey , Raphael Borie et al.
Human Molecular Genetics, 2020, 29 (6), pp.907-922. ⟨10.1093/hmg/ddaa011⟩
Article dans une revue hal-02458897 v1
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Ribosomal protein gene RPL9 variants can differentially impair ribosome function and cellular metabolism

Marco Lezzerini , Marianna Penzo , Marie-Françoise O'Donohue , Carolina Marques dos Santos Vieira , Manon Saby et al.
Nucleic Acids Research, 2020, 48 (2), pp.770-787. ⟨10.1093/nar/gkz1042⟩
Article dans une revue hal-02551186 v1
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Impaired telomere integrity and rRNA biogenesis in PARN‐deficient patients and knock‐out models

Maname Benyelles , Harikleia Episkopou , Marie-Françoise O'Donohue , Laetitia Kermasson , Pierre Frange et al.
EMBO Molecular Medicine, 2019, 11 (7), pp.e10201. ⟨10.15252/emmm.201810201⟩
Article dans une revue hal-02327835 v1
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Conformational proofreading of distant 40S ribosomal subunit maturation events by a long-range communication mechanism

Valentin Mitterer , Ramtin Shayan , Sébastien Ferreira-Cerca , Guillaume Murat , Tanja Enne et al.
Nature Communications, 2019, 10 (1), pp.2754. ⟨10.1038/s41467-019-10678-z⟩
Article dans une revue hal-02399643 v1
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Mammalian Hbs1L deficiency causes congenital anomalies and developmental delay associated with Pelota depletion and 80S monosome accumulation

Amy O'Connell , Maxim Gerashchenko , Marie-Françoise O'Donohue , Samantha Rosen , Eric Huntzinger et al.
PLoS Genetics, 2019, 15 (2), pp.e1007917. ⟨10.1371/journal.pgen.1007917⟩
Article dans une revue hal-02327840 v1
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The path of pre-ribosomes through the nuclear pore complex revealed by electron tomography

Franck Delavoie , Vanessa Soldan , Dana Rinaldi , Jean-Yves Dauxois , Pierre-Emmanuel Gleizes
Nature Communications, 2019, 10 (1), pp.497. ⟨10.1038/s41467-019-08342-7⟩
Article dans une revue hal-02000677 v1
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RPL13 Variants Cause Spondyloepimetaphyseal Dysplasia with Severe Short Stature

Cedric Le Caignec , Benjamin Ory , François Lamoureux , Marie-Françoise O'Donohue , Emilien Orgebin et al.
American Journal of Human Genetics, 2019, 105 (5), pp.1040-1047. ⟨10.1016/j.ajhg.2019.09.024⟩
Article dans une revue hal-02327833 v1
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Pre-Ribosomal RNA Processing in Human Cells: From Mechanisms to Congenital Diseases

Maxime Aubert , Marie-Françoise O'Donohue , Simon Lebaron , Pierre-Emmanuel Gleizes
Biomolecules, 2018, 8 (4), pp.123. ⟨10.3390/biom8040123⟩
Article dans une revue hal-02327845 v1

Cross talk between TP53 and c-Myc in the pathophysiology of Diamond-Blackfan anemia: Evidence from RPL11-deficient in vivo and in vitro models

Anirban Chakraborty , Tamayo Uechi , Yukari Nakajima , Hanna Gazda , Marie-Françoise O'Donohue et al.
Biochemical and Biophysical Research Communications, 2018, 495 (2), pp.1839-1845. ⟨10.1016/j.bbrc.2017.12.019⟩
Article dans une revue hal-02327850 v1

Maturation of pre‐40S particles in yeast and humans

Emilie Cerezo , Célia Plisson‐chastang , Anthony K Henras , Simon Lebaron , Pierre‐emmanuel Gleizes et al.
Wiley Interdisciplinary Reviews: RNA, 2018, 10 (1), pp.e1516. ⟨10.1002/WRNA.1516⟩
Article dans une revue hal-02399840 v1
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Recurring mutations in RPL15 are linked to hydrops fetalis and treatment independence in Diamond-Blackfan anemia

Marcin Wlodarski , Lydie da Costa , Marie-Françoise O'Donohue , Marc Gastou , Narjesse Karboul et al.
Haematologica, 2018, 103 (6), pp.949-958. ⟨10.3324/haematol.2017.177980⟩
Article dans une revue hal-02327846 v1
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The Genetic Landscape of Diamond-Blackfan Anemia

Jacob Ulirsch , Jeffrey Verboon , Shideh Kazerounian , Michael Guo , Daniel Yuan et al.
American Journal of Human Genetics, 2018, 103 (6), pp.930-947. ⟨10.1016/j.ajhg.2018.10.027⟩
Article dans une revue hal-02328160 v1
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RNA helicase, DDX27 regulates skeletal muscle growth and regeneration by modulation of translational processes

Alexis Bennett , Marie-Françoise O'Donohue , Stacey Gundry , Aye Chan , Jeffrey Widrick et al.
PLoS Genetics, 2018, 14 (3), pp.e1007226. ⟨10.1371/journal.pgen.1007226⟩
Article dans une revue hal-02327847 v1
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Molecular approaches to diagnose Diamond-Blackfan anemia: The EuroDBA experience

Lydie da Costa , Marie-Françoise O'Donohue , Birgit van Dooijeweert , Katarzyna Albrecht , Sule Unal et al.
European Journal of Medical Genetics, 2018, 61 (11), pp.664-673. ⟨10.1016/j.ejmg.2017.10.017⟩
Article dans une revue (article de synthèse) hal-02327861 v1
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A Ribosomopathy Reveals Decoding Defective Ribosomes Driving Human Dysmorphism

Nahuel Paolini , Martin Attwood , Samuel Sondalle , Carolina Marques dos Santos Vieira , Anita van Adrichem et al.
American Journal of Human Genetics, 2017, 100 (3), pp.506-522. ⟨10.1016/j.ajhg.2017.01.034⟩
Article dans une revue hal-02327866 v1
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Poly(A)-specific ribonuclease is a nuclear ribosome biogenesis factor involved in human 18S rRNA maturation

Christian Montellese , Nathalie Montel-Lehry , Anthony K Henras , Ulrike Kutay , Pierre-Emmanuel Gleizes et al.
Nucleic Acids Research, 2017, 45 (11), pp.6822-6836. ⟨10.1093/nar/gkx253⟩
Article dans une revue hal-02327863 v1

Characterization of the lipid envelope of exosome encapsulated HEV particles protected from the immune response

Sabine Chapuy-Regaud , Martine Dubois , Celia Plisson-Chastang , Tiffany Bonnefois , Sébastien Lhomme et al.
Biochimie, 2017, 141, pp.70-79. ⟨10.1016/J.BIOCHI.2017.05.003⟩
Article dans une revue hal-02399744 v1
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The NEDD8 inhibitor MLN4924 increases the size of the nucleolus and activates p53 through the ribosomal-Mdm2 pathway

Aymeric Bailly , Aurélien Perrin , Lara J. Bou Malhab , Emmanuelle Pion , Mark Larance et al.
Oncogene, 2016, 35 (4), pp.415--426. ⟨10.1038/onc.2015.104⟩
Article dans une revue hal-01878024 v1
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Structure of a human pre-40S particle points to a role for RACK1 in the final steps of 18S rRNA processing

Natacha Larburu , Christian Montellese , Marie-Françoise O'Donohue , Ulrike Kutay , Pierre-Emmanuel Gleizes et al.
Nucleic Acids Research, 2016, 44 (17), pp.8465-8478. ⟨10.1093/nar/gkw714⟩
Article dans une revue hal-02327869 v1

Ribosomal 60S-subunit production: the final scene

Celia Plisson-Chastang , Natacha Larburu , Pierre-Emmanuel Gleizes
Nature Structural and Molecular Biology, 2015, 22 (11), pp.837-838. ⟨10.1038/NSMB.3121⟩
Article dans une revue hal-02399901 v1
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An overview of pre-ribosomal RNA processing in eukaryotes

Anthony K Henras , Célia Plisson-Chastang , Marie-Françoise O'Donohue , Anirban Chakraborty , Pierre-Emmanuel Gleizes
Wiley Interdisciplinary Reviews: RNA, 2015, 6 (2), pp.225-242. ⟨10.1002/wrna.1269⟩
Article dans une revue hal-02327876 v1
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Germline Mutation of RPS20, Encoding a Ribosomal Protein, Causes Predisposition to Hereditary Nonpolyposis Colorectal Carcinoma Without DNA Mismatch Repair Deficiency

Taina T Nieminen , Marie-Françoise O'Donohue , Yunpeng Wu , Hannes H. Lohi , Stephen W. Scherer et al.
Gastroenterology, 2014, 147 (3), pp.595-598.e5. ⟨10.1053/j.gastro.2014.06.009⟩
Article dans une revue hal-02327878 v1

Gradual processing of the ITS1 from the nucleolus to the cytoplasm during synthesis of the human 18S rRNA

Milena Preti , Marie-Françoise O'Donohue , Nathalie Montel-Lehry , Marie-Line Bortolin-Cavaillé , Valérie Choesmel et al.
Nucleic Acids Research, 2013, 41 (8), pp.4709-4723. ⟨10.1093/nar/gkt160⟩
Article dans une revue hal-02327882 v1

Novel deletion of RPL15 identified by array-comparative genomic hybridization in Diamond–Blackfan anemia

Michael Landowski , Marie-Françoise O'Donohue , Christopher Buros , Roxanne Ghazvinian , Nathalie Montel-Lehry et al.
Human Genetics, 2013, 132 (11), pp.1265-1274. ⟨10.1007/s00439-013-1326-z⟩
Article dans une revue hal-02327880 v1

Frameshift mutation in p53 regulator RPL26 is associated with multiple physical abnormalities and a specific pre-rRNA processing defect in Diamond-Blackfan anemia.

Hanna T Gazda , Milena Preti , Mee Rie Sheen , Marie-Françoise O'Donohue , Adrianna Vlachos et al.
Human Mutation, 2012, epub ahead of print. ⟨10.1002/humu.22081⟩
Article dans une revue hal-00688367 v1

Diamond Blackfan anemia: ribosomal proteins going rogue.

Steven R Ellis , Pierre-Emmanuel Gleizes
Seminars in Hematology, 2011, 48 (2), pp.89-96. ⟨10.1053/j.seminhematol.2011.02.005⟩
Article dans une revue hal-00611893 v1

Analysis of two human pre-ribosomal factors, bystin and hTsr1, highlights differences in evolution of ribosome biogenesis between yeast and mammals.

Coralie Carron , Marie-Françoise O'Donohue , Valérie Choesmel , Marlène Faubladier , Pierre-Emmanuel Gleizes
Nucleic Acids Research, 2011, 39 (1), pp.280-91. ⟨10.1093/nar/gkq734⟩
Article dans une revue hal-00611891 v1

Ribosomal Protein Genes RPS10 and RPS26 Are Commonly Mutated in Diamond-Blackfan Anemia

Leana Doherty , Mee Rie Sheen , Adrianna Vlachos , Valérie Choesmel , Marie-Françoise O'Donohue et al.
American Journal of Human Genetics, 2010, 86 (2), pp.222-228. ⟨10.1016/j.ajhg.2009.12.015⟩
Article dans une revue hal-02328188 v1

Genetic interactions show the importance of rRNA modification machinery for the role of Rps15p during ribosome biogenesis in S. cerevisiae.

Clément Bellemer , Pauline Chabosseau , Franck Gallardo , Pierre-Emmanuel Gleizes , Guillaume Stahl
PLoS ONE, 2010, 5 (5), pp.e10472. ⟨10.1371/journal.pone.0010472⟩
Article dans une revue hal-00611838 v1

Functional dichotomy of ribosomal proteins during the synthesis of mammalian 40S ribosomal subunits.

Marie-Françoise O'Donohue , Valérie Choesmel , Marlène Faubladier , Gwennaële Fichant , Pierre-Emmanuel Gleizes
Journal of Cell Biology, 2010, 190 (5), pp.853-66. ⟨10.1083/jcb.201005117⟩
Article dans une revue hal-00611842 v1

[Diamond-Blackfan anemia reveals the dark side of ribosome biogenesis].

Almass-Houd Aguissa-Touré , Lydie da Costa , Thierry Leblanc , Gil Tchernia , Sébastien Fribourg et al.
Médecine/Sciences, 2009, 25 (1), pp.69-76. ⟨10.1051/medsci/200925169⟩
Article dans une revue hal-00611739 v1

Distinct cytoplasmic maturation steps of 40S ribosomal subunit precursors require hRio2

Ivo Zemp , Thomas Wild , Marie-Françoise O'Donohue , Franziska Wandrey , Barbara Widmann et al.
Journal of Cell Biology, 2009, 185 (7), pp.1167-1180. ⟨10.1083/jcb.200904048⟩
Article dans une revue hal-02328194 v1

Mutation of ribosomal protein RPS24 in Diamond-Blackfan anemia results in a ribosome biogenesis disorder

Valérie Choesmel , Sébastien Fribourg , Almass-Houd Aguissa-Touré , Noël Pinaud , Pierre Legrand et al.
Human Molecular Genetics, 2008, 17 (9), pp.1253-63. ⟨10.1093/hmg/ddn015⟩
Article dans une revue hal-00308960 v1

Ribosomal Protein L5 and L11 Mutations Are Associated with Cleft Palate and Abnormal Thumbs in Diamond-Blackfan Anemia Patients

Hanna Gazda , Mee Rie Sheen , Adrianna Vlachos , Valérie Choesmel , Marie-Françoise O'Donohue et al.
American Journal of Human Genetics, 2008, 83 (6), pp.769-780. ⟨10.1016/j.ajhg.2008.11.004⟩
Article dans une revue hal-02328204 v1

RPS19 mutations in patients with Diamond-Blackfan anemia

Maria Francesca Campagnoli , Ugo Ramenghi , Marta Armiraglio , Paola Quarello , Emanuela Garelli et al.
Human Mutation, 2008, 29 (7), pp.911-20. ⟨10.1002/humu.20752⟩
Article dans une revue hal-00308963 v1

Impaired ribosome biogenesis in Diamond-Blackfan anemia.

Valérie Choesmel , Daniel Bacqueville , Jacques Rouquette , Jacqueline Noaillac-Depeyre , Sébastien Fribourg et al.
Blood, 2007, 109 (3), pp.1275-83. ⟨10.1182/blood-2006-07-038372⟩
Article dans une revue hal-00308965 v1
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Molecular basis of Diamond Blackfan anemia: structure and function analysis of RPS19.

Lynn A. Gregory , Almass-Houd Aguissa-Touré , Noël Pinaud , Pierre Legrand , Pierre-Emmanuel Gleizes et al.
Nucleic Acids Research, 2007, 35 (17), pp.5913-5921. ⟨10.1093/nar/gkm626⟩
Article dans une revue inserm-00175611 v1

Expression of truncated latent TGF-beta-binding protein modulates TGF-beta signaling.

Roberta Mazzieri , Vladimir Jurukovski , Hiroto Obata , Joanne Sung , Alec Platt et al.
Journal of Cell Science, 2005, 119 (10), pp.2177-87. ⟨10.1242/jcs.02352⟩
Article dans une revue hal-00022334 v1

Nuclear export and cytoplasmic processing of precursors to the 40S ribosomal subunits in mammalian cells

Jacques Rouquette , Valérie Choesmel , Pierre-Emmanuel Gleizes
EMBO Journal, 2005, 24 (16), pp.2862-72. ⟨10.1038/sj.emboj.7600752⟩
Article dans une revue hal-00022340 v1
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Roles of eukaryotic ribosomal proteins in maturation and transport of pre-18S rRNA and ribosome function

S. Ferreira-Cerca , Gisela Pöll , Pierre-Emmanuel Gleizes , Herbert Tschochner , Philipp Milkereit
Molecular and Cellular Biology, 2005, 20 (2), pp.263-275. ⟨10.1016/j.molcel.2005.09.005⟩
Article dans une revue hal-00021190 v1

Specific Role for Yeast Homologs of the Diamond Blackfan Anemia associated Rps19 Protein in Ribosome Synthesis

Isabelle Léger-Silvestre , Jacqueline Marie Caffrey , Rosy Dawaliby , Diana Alehandrovna Alvarez-Arias , Nicole Gas et al.
Journal of biology and chemistry, 2005, 280 (46), pp.38177-85. ⟨10.1074/jbc.M506916200⟩
Article dans une revue hal-00022332 v1

The ribosomal protein Rps15p is required for nuclear exit of the 40S subunit precursors in yeast

Isabelle Léger-Silvestre , Philipp Milkereit , Sébastien Ferreira-Cerca , Cosmin Saveanu , Jean-Claude Rousselle et al.
EMBO Journal, 2004, 23 (12), pp.2336 - 2347. ⟨10.1038/sj.emboj.7600252⟩
Article dans une revue hal-00022401 v1

Late cytoplasmic maturation of the small ribosomal subunit requires RIO proteins in Saccharomyces cerevisiae

Emmanuel Vanrobays , Jean-Paul Gélugne , Pierre‐emmanuel Gleizes , Michele Caizergues-Ferrer
Molecular and Cellular Biology, 2003, 23 (6), pp.2083-95. ⟨10.1128/MCB.23.6.2083-2095.2003⟩
Article dans une revue hal-00022445 v1
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Sequential protein association with nascent 60S ribosomal particles

Cosmin Saveanu , Abdelkader Namane , Pierre-Emmanuel Gleizes , Alice Lebreton , Jean-Claude Rousselle et al.
Molecular and Cellular Biology, 2003, 23 (13), pp.4449-60. ⟨10.1128/MCB.23.13.4449-4460.2003⟩
Article dans une revue hal-01350680 v1
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Nog2p, a putative GTPase associated with pre-60S subunits and required for late 60S maturation steps

Cosmin Saveanu , D. Bienvenu , A. Namane , P. E. Gleizes , Nicole Gas et al.
EMBO Journal, 2001, 20 (22), pp.6475--6484. ⟨10.1093/emboj/20.22.6475⟩
Article dans une revue pasteur-01404705 v1

Hybrid and complex glycans are linked to the conserved N-glycosylation site of the third eight-cysteine domain of LTBP-1 in insect cells.

P Rudd , A.K Downing , Martine Cadene , D.J Harvey , M.R Wormald et al.
Biochemistry, 2000, 39 (7), pp.1596-1603. ⟨10.1021/bi9918285⟩
Article dans une revue istex hal-02150367 v1