Accéder directement au contenu
PT

Pierre-Louis Tharaux

83%
Libre accès
24
Documents
Affiliations actuelles
  • 1004693
  • 303623
  • 1042190
Identifiants chercheurs
Contact
Site web
  • http://parcc.inserm.fr/research-teams/team/tharaux-camerer/

Présentation

Domaines de recherche

Sciences du Vivant [q-bio] Médecine humaine et pathologie

Compétences

Biologie vasculaire Auto-immunité maladies rares Néphrologie Hypertension Fibrose Drépanocytose Maladies métaboliques cardiovasculaire diabète

Publications

"olivia-lenoir"

BMP9 is a key player in endothelial identity and its loss is sufficient to induce arteriovenous malformations

Agnes Desroches-Castan , Dzenis Koca , Hequn Liu , Caroline Roelants , Léa Resmini
Cardiovascular Research, 2024, ⟨10.1093/cvr/cvae052⟩
Article dans une revue hal-04543282v1

Podocyte Injury in Diabetic Kidney Disease in Mouse Models Involves TRPC6-mediated Calpain Activation Impairing Autophagy

Yann Salemkour , Dilemin Yildiz , Léa Dionet , Kim A.T. Verheijden , Ryuta Saito
Journal of the American Society of Nephrology, 2023, 34 (11), pp.1823-1842. ⟨10.1681/ASN.0000000000000212⟩
Article dans une revue hal-04361228v1
Image document

ScoMorphoFISH: A deep learning enabled toolbox for single‐cell single‐mRNA quantification and correlative (ultra‐)morphometry

Florian Siegerist , Eleonora Hay , Juan Saydou Dikou , Marion Pollheimer , Anja Büscher
Journal of Cellular and Molecular Medicine, 2022, 26 (12), pp.3513-3526. ⟨10.1111/jcmm.17392⟩
Article dans une revue inserm-03788311v1

Should we consider calcimimetics as a therapeutic option for nephrotic syndrome?

Olivia Lenoir , Pierre-Louis Tharaux
Kidney International, 2022, 101 (6), pp.1110-1112. ⟨10.1016/j.kint.2022.04.008⟩
Article dans une revue inserm-03788305v1

FIBER-ML, an Open-Source Supervised Machine Learning Tool for Quantification of Fibrosis in Tissue Sections

Caterina Facchin , Anais Certain , Thulaciga Yoganathan , Clement Delacroix , Alicia Arevalo Garcia
American Journal of Pathology, 2022, 192 (5), pp.783-793. ⟨10.1016/j.ajpath.2022.01.013⟩
Article dans une revue inserm-03788337v1

MicroRNAs in kidney injury and disease

Nassim Mahtal , Olivia Lenoir , Claire Tinel , Dany Anglicheau , Pierre-Louis Tharaux
Nature Reviews Nephrology, 2022, 18 (10), pp.643-662. ⟨10.1038/s41581-022-00608-6⟩
Article dans une revue inserm-03787575v1
Image document

Calpastatin prevents Angiotensin II–mediated podocyte injury through maintenance of autophagy

Imane Bensaada , Blaise Robin , Joëlle Perez , Yann Salemkour , Anna Chipont
Kidney International, 2021, 100 (1), pp.90 - 106. ⟨10.1016/j.kint.2021.02.024⟩
Article dans une revue hal-03918903v1

Effect of Tocilizumab vs Usual Care in Adults Hospitalized With COVID-19 and Moderate or Severe Pneumonia

Olivier Hermine , Xavier Mariette , Pierre-Louis Tharaux , Matthieu Resche-Rigon , Raphaël Porcher
JAMA Internal Medicine, 2021, 181 (1), pp.32-40. ⟨10.1001/jamainternmed.2020.6820⟩
Article dans une revue hal-03579175v1

Effect of anakinra versus usual care in adults in hospital with COVID-19 and mild-to-moderate pneumonia (CORIMUNO-ANA-1): a randomised controlled trial

Pierre-Louis Tharaux , Gilles Pialoux , Arthur Pavot , Xavier Mariette , Olivier Hermine
The Lancet Respiratory Medicine, 2021, 9 (3), pp.295-304. ⟨10.1016/S2213-2600(20)30556-7⟩
Article dans une revue hal-03579180v1

Deletion of the myeloid endothelin-B receptor confers long-term protection from angiotensin II-mediated kidney, eye and vessel injury

Léa Guyonnet , Alicja Czopek , Tariq Farrah , Véronique Baudrie , Philippe Bonnin
Kidney International, 2020, 98 (5), pp.1193-1209. ⟨10.1016/j.kint.2020.05.042⟩
Article dans une revue hal-03832377v1

Podocytes maintain high basal levels of autophagy independent of mtor signaling

Tillmann Bork , Wei Liang , Kosuke Yamahara , Philipp Lee , Zhejia Tian
Autophagy, 2020, 16 (11), pp.1932-1948. ⟨10.1080/15548627.2019.1705007⟩
Article dans une revue hal-03832381v1
Image document

Deletion of the myeloid endothelin-B receptor confers long-term protection from angiotensin II-mediated kidney, eye and vessel injury

Léa Guyonnet , Alicja Czopek , Tariq E Farrah , Véronique Baudrie , Philippe Bonnin
Kidney International, 2020, 98 (5), pp.1193-1209. ⟨10.1016/j.kint.2020.05.042⟩
Article dans une revue hal-03268543v1
Image document

Rôle pathogénique de l’expression anormale de la tétraspanine CD9 par les cellules épithéliales pariétales dans les glomérulopathies extracapillaires

Hélène Lazareth , Olivia Lenoir , Carole Hénique , Cédric Bouzigues , Claude Boucheix
Médecine/Sciences, 2020, 36 (10), pp.852-855. ⟨10.1051/medsci/2020154⟩
Article dans une revue hal-02960790v1
Image document

Podocytes maintain high basal levels of autophagy independent of mtor signaling

Tillmann Bork , Wei Liang , Kosuke Yamahara , Philipp Lee , Zhejia Tian
Autophagy, 2019, 23, pp.1-17. ⟨10.1080/15548627.2019.1705007⟩
Article dans une revue inserm-02439016v1
Image document

Local miscommunications between glomerular cells as potential therapeutic targets for crescentic glomerulonephritides

Carole Hénique , Olivia Lenoir , Alexandre Karras , Pierre-Louis Tharaux
Néphrologie & Thérapeutique, 2019, 15, pp.S1 - S5. ⟨10.1016/j.nephro.2019.03.006⟩
Article dans une revue hal-03485068v1
Image document

A novel role for myeloid endothelin-B receptors in hypertension

Alicja Czopek , Rebecca Moorhouse , Léa Guyonnet , Tariq Farrah , Olivia Lenoir
European Heart Journal, 2019, 40 (9), pp.768-784. ⟨10.1093/eurheartj/ehy881⟩
Article dans une revue inserm-02439065v1
Image document

The tetraspanin CD9 controls migration and proliferation of parietal epithelial cells and glomerular disease progression

Hélène Lazareth , Carole Henique , Olivia Lenoir , Victor Puelles , Martin Flamant
Nature Communications, 2019, 10 (1), pp.3303. ⟨10.1038/s41467-019-11013-2⟩
Article dans une revue inserm-02439082v1
Image document

A novel role for myeloid endothelin-B receptors in hypertension

Alicja Czopek , Rebecca Moorhouse , Léa Guyonnet , Tariq Farrah , Olivia Lenoir
European Heart Journal, 2019, 40 (9), pp.768 - 784. ⟨10.1093/eurheartj/ehy881⟩
Article dans une revue hal-03918917v1
Image document

Hmox1 Deficiency Sensitizes Mice to Peroxynitrite Formation and Diabetic Glomerular Microvascular Injuries

Olivia Lenoir , François Gaillard , Hélène Lazareth , Blaise Robin , Pierre-Louis Tharaux
Journal of diabetes research, 2017, 2017, pp.1-7. ⟨10.1155/2017/9603924⟩
Article dans une revue hal-03832394v1
Image document

The endothelin B receptor plays a crucial role in the adhesion of neutrophils to the endothelium in sickle cell disease

Bérengère Koehl , Pierre Nivoit , Wassim El Nemer , Olivia Lenoir , Patricia Hermand
Haematologica, 2017, 102 (7), pp.1161-1172. ⟨10.3324/haematol.2016.156869⟩
Article dans une revue hal-03832400v1
Image document

Endothelial Epas1 Deficiency Is Sufficient To Promote Parietal Epithelial Cell Activation and FSGS in Experimental Hypertension

Yosu Luque , Olivia Lenoir , Philippe Bonnin , Lise Hardy , Anna Chipont
Journal of the American Society of Nephrology, 2017, 28 (12), pp.3563-3578. ⟨10.1681/ASN.2016090960⟩
Article dans une revue hal-01713482v1
Image document

Genetic and pharmacological inhibition of microRNA-92a maintains podocyte cell cycle quiescence and limits crescentic glomerulonephritis

Carole Henique , Guillaume Bollée , Xavier Loyer , Florian F. Grahammer , Neeraj Dhaun
Nature Communications, 2017, 8 (1), pp.1829. ⟨10.1038/s41467-017-01885-7⟩
Article dans une revue inserm-02439029v1

Endothelial cell and podocyte autophagy synergistically protect from diabetes-induced glomerulosclerosis

Olivia Lenoir , Magali Jasiek , Carole Henique , Lea Guyonnet , Bjoern Hartleben
Autophagy, 2015, 11 (7), pp.1130-1145. ⟨10.1080/15548627.2015.1049799⟩
Article dans une revue hal-01539607v1
Image document

Direct Action of Endothelin-1 on Podocytes Promotes Diabetic Glomerulosclerosis

Olivia Lenoir , Marine Milon , Anne Virsolvy , Carole Henique , Alain Schmitt
Journal of the American Society of Nephrology, 2014, 25 (5), pp.1050-1062. ⟨10.1681/ASN.2013020195⟩
Article dans une revue hal-02542297v1